Q:

Disable Taskbar in Windows 10

Is there any way to completely disable the taskbar in Windows 10 Home?  I have a C# app that I want to display fullscreen on clients' displays without any sign of it running on Windows.  It's supposed to run on startup and display a website.  
I created a setup that changes most of the Windows settings via registry, like hiding desktop icons and altering logon view, but the taskbar remains visible.  Auto hide doesn't satisfy me, because after the system boots the taskbar is still visible until you actually click somewhere on the desktop, and it takes a while for my app to run.  I'd really appreciate some help. 

A:

When explorer is running, there taskbar will always be visible in some kind (even if it's a small border). 
If you want to achieve something like a digital signage solution, you may replace the shell.  Changing the shell will also provide some other benefits (most popups / balloontips won't occur anymore). 
Be aware that this configuration is effective for all users on the system. 
Path to the shell is available at
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows NT\CurrentVersion\WinLogon\Shell

Update:
Just to hightlight: 
It is indeed possible to have custom shells per user (see comments). 
This is done by specifying a custom location of the shell path that is located in the registry for a given user.