Non-alcoholic fatty liver disease (NAFLD) refers to fat accumulation in the liver that is not related to alcohol consumption.  Fat may accumulate as a result of obesity, diabetes or other conditions.  In a small number of people, NAFLD progresses to liver inflammation, scarring and, eventually, liver failure.  This serious form of the disease is sometimes called non-alcoholic steatohepatitis (NASH).  NAFLD and NASH, and conditions leading to or arising from one or more of them, are a growing problem worldwide, affecting people of every age.  NAFLD and NASH are currently the fastest-rising indicator for liver transplant.