Combined experimental and theoretical study of long-range H-F interactions in α-fluoro amides. 
A combined experimental and computational approach provided insight into the nature and conformational dependence of long-range 4JHF couplings in α-fluoro amides.  The dependence of 4JHF on substituents and the solvent was investigated.  H-F coupling constants determined by NMR spectroscopy are in agreement with DFT calculations.  NBO analysis revealed that a favourable nF→σNH* interaction correlates with the magnitude of 4JHF.