Famo.us - SF Fulltime (<a href="http://www.famo.us" >http://www.famo.us</a>)
We make 3D interfaces and cross-platform apps on top of WebKit browsers. We're a big javascript house, and don't use any 3rd party libraries for our main platform, though experience with MVC libraries, three.js, D3.js, Node are all pluses.
If you want to replace jQuery, send me an email: REDACTED_EMAIL