Datasets:
chintagunta85
/
bionlp2

Dataset card Viewer Files Community
id
stringlengths
1
5
tokens
sequence
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sequence
0
[ "Since", "HUVECs", "released", "superoxide", "anions", "in", "response", "to", "TNF", ",", "and", "H2O2", "induces", "VCAM-1", ",", "PDTC", "may", "act", "as", "a", "radical", "scavenger", "." ]
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[ "Although", "ICAM-1", "induction", "was", "unaffected", ",", "inhibitors", "of", "NADPH", "oxidase", "(", "apocynin", ")", "or", "cytochrome", "P-450", "(", "SKF525a", ")", "suppressed", "VCAM-1", "induction", "by", "TNF", ",", "revealing", "that", "several", "radical-generating", "systems", "are", "involved", "in", "its", "regulation", "." ]
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[ "PDTC", ",", "apocynin", ",", "or", "SKF525a", "decreased", "adhesion", "of", "monocytic", "U937", "cells", "to", "TNF-treated", "HUVECs", "(", "by", "75", "%", "at", "100", "mumol/L", "PDTC", ")", "." ]
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[ "Inhibition", "by", "anti-VCAM-1", "monoclonal", "antibody", "1G11", "indicated", "that", "U937", "adhesion", "was", "VCAM-1", "dependent", "and", "suppression", "by", "antioxidants", "was", "due", "to", "reduced", "VCAM-1", "induction", "." ]
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[ "(", "ABSTRACT", "TRUNCATED", "AT", "250", "WORDS", ")" ]
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[ "Displacement", "of", "an", "E-box-binding", "repressor", "by", "basic", "helix-loop-helix", "proteins", ":", "implications", "for", "B-cell", "specificity", "of", "the", "immunoglobulin", "heavy-chain", "enhancer", "." ]
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[ "The", "activity", "of", "the", "immunoglobulin", "heavy-chain", "(", "IgH", ")", "enhancer", "is", "restricted", "to", "B", "cells", ",", "although", "it", "binds", "both", "B-cell-restricted", "and", "ubiquitous", "transcription", "factors", "." ]
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[ "Activation", "of", "the", "enhancer", "in", "non-B", "cells", "upon", "overexpression", "of", "the", "basic", "helix-loop-helix", "(", "bHLH", ")", "protein", "E2A", "appears", "to", "be", "mediated", "not", "only", "by", "the", "binding", "of", "E2A", "to", "its", "cognate", "E", "box", "but", "also", "by", "the", "resulting", "displacement", "of", "a", "repressor", "from", "that", "same", "site", "." ]
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[ "We", "have", "identified", "a", "``", "two-handed", "''", "zinc", "finger", "protein", ",", "denoted", "ZEB", ",", "the", "DNA-binding", "specificity", "of", "which", "mimics", "that", "of", "the", "cellular", "repressor", "." ]
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[ "By", "employing", "a", "derivative", "E", "box", "that", "binds", "ZEB", "but", "not", "E2A", ",", "we", "have", "shown", "that", "the", "repressor", "is", "active", "in", "B", "cells", "and", "the", "IgH", "enhancer", "is", "silenced", "in", "the", "absence", "of", "binding", "competition", "by", "bHLH", "proteins", "." ]
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[ "Hence", ",", "we", "propose", "that", "a", "necessary", "prerequisite", "of", "enhancer", "activity", "is", "the", "B-cell-specific", "displacement", "of", "a", "ZEB-like", "repressor", "by", "bHLH", "proteins", "." ]
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[ "Inhibition", "of", "NF-kappa", "B", "by", "sodium", "salicylate", "and", "aspirin", "[", "see", "comments", "]" ]
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[ "The", "transcription", "factor", "nuclear", "factor-kappa", "B", "(", "NF-kappa", "B", ")", "is", "critical", "for", "the", "inducible", "expression", "of", "multiple", "cellular", "and", "viral", "genes", "involved", "in", "inflammation", "and", "infection", "including", "interleukin-1", "(", "IL-1", ")", ",", "IL-6", ",", "and", "adhesion", "molecules", "." ]
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[ "Effects", "of", "the", "antisense", "myb", "expression", "on", "hemin-", "and", "erythropoietin-", "induced", "erythroid", "differentiation", "of", "K562", "cells", "." ]
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[ "The", "amount", "of", "c-myb", "mRNA", "in", "K562", "cells", "was", "reduced", "during", "the", "differentiation", "induced", "by", "Epo", "." ]
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[ "Expression", "of", "GATA-1", "mRNA", "was", "almost", "constant", "during", "Hm", "-induced", "differentiation", ",", "but", "increased", "during", "Epo", "treatment", "." ]
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[ "Prenatal", "immune", "challenge", "alters", "the", "hypothalamic-pituitary-adrenocortical", "axis", "in", "adult", "rats", "." ]
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