The outbreak and the warnings come as a potential blow to tourism in one of the world's busiest travel hubs, which is already struggling to recover from a slump amid tepid global growth.

Singapore reported its first case of locally-transmitted Zika at the weekend, and the number of reported infections of the mosquito-borne virus has since jumped to 56. At least three dozen of those have since made a full recovery.

The Zika virus was detected in Brazil last year and has since spread across the Americas. It poses a risk to pregnant women because it can cause severe birth defects. It has been linked in Brazil to more than 1,800 cases of microcephaly, a rare birth defect where babies are born with abnormally small heads and brains.

The 56 confirmed cases in Singapore include only one woman.

Taiwan, Australia and South Korea advised pregnant women and those planning pregnancy to postpone trips to Singapore. Those returning from the country should avoid pregnancy for two months. South Korean travelers will receive text messages with the warning when they arrive in Singapore.

Malaysia and Indonesia, Singapore's closest neighbors, have stepped up protective measures following the outbreak, introducing thermal scanners at airports and border checkpoints.

Singapore's Tourism Board said it was monitoring developments, adding the city state remained a "safe travel destination", and it was premature to consider any impact.

More than 55 million people pass through Singapore's Changi airport every year. In the first half of this year, tourism arrivals reached almost 8.2 million, compared with around 7.3 million in the same period of last year.

Online retailer Lazada Singapore said on Tuesday it has seen sales of mosquito repellent and other deterrent products rise fivefold over the past three days compared to a week ago.

Authorities continued to inspect thousands of homes in seven parts of Singapore, including five foreign worker dormitories, on Tuesday. Officials sprayed insecticide and removed potential mosquito breeding habitats such as stagnant water and moist dirt from drains.

The majority of those infected with Zika in Singapore were foreign workers, but the government has not disclosed their nationalities. The High Commission of Bangladesh, which represents the largest community of foreign workers, said none of the workers were Bangladeshis.

The Chinese and Myanmar embassies in Singapore said they had not been notified by Singapore whether their citizens were among those infected. The Thai embassy did not immediately return a call seeking comment.

Foreign workers in Singapore, employed mostly in the construction and marine industries, can earn as little as S$2 ($1.47) an hour, often work 12-14 hours a day and take few days off. They are unlikely to travel often.

The GuocoLand construction site, where the infected workers were found, remained closed on Tuesday morning, according to a Reuters photographer at the scene. It was ordered on Sunday to halt work and rectify the conditions that allowed mosquitoes to breed.

Regional health experts said the Zika virus is likely to be significantly under-reported across tropical Southeast Asia as local health authorities fail to conduct adequate screening. </s> KUALA LUMPUR/SINGAPORE, Sept 1 (Reuters) - Malaysia reported its first case of Zika on Thursday, a woman who tested positive for the mosquito-borne virus after a visit to neighbouring Singapore, where 115 people have so far been infected, many of them foreigners.

The 58-year-old victim had shown signs of a rash and fever one week after her return from Singapore on August 21, said Malaysian Health Minister Subramaniam Sathasivam.

"We are carrying out control measures against aedes mosquitoes near the woman's home to prevent the spread of the virus," he told a news conference.

The Zika virus, which has spread through the Americas and the Caribbean since late last year, is generally a mild disease but is a particular risk to pregnant women. It has been linked to microcephaly - a severe birth defect in which babies are born with abnormally small heads and underdeveloped brains.

The U.S. Centers for Disease Control and Prevention had said Singapore is the only Asian nation with an active Zika virus transmission. Officials in the city-state, one of the world's largest financial centres and busiest travel hubs, reported the first locally transmitted infection on Saturday and said on Wednesday the number had jumped to 115.

Singapore authorities detected infections in people living outside the initial outbreak area and have identified a potential second cluster. A pregnant woman was among the victims, they said.

"Over time, we expect Zika cases to emerge from more areas," Singapore's Minister for Health Gan Kim Yong said in a statement on Wednesday. "We must work and plan on the basis that there is Zika transmission in other parts of Singapore and extend our vector control efforts beyond the current affected areas."

Five Malaysians in Singapore had tested positive for Zika, including the latest victim's adult daughter, who works in Singapore, the Malaysian minister said.

Twenty-one Chinese nationals, 13 Indians, six Bangladeshis, and an Indonesian are also among the 115 cases of Zika reported in Singapore, foreign officials said.

Many are believed to be overseas workers at building sites in Singapore, although the Singapore government has not given details of the victims by nationality.

The United States, Australia, Taiwan, South Korea and Indonesia have warned pregnant women not to travel to Singapore.

The outbreak and advisories come as the tourism industry in Singapore already faces weak global economic growth. Singapore's Tourism Board said it was premature to consider any impact on the sector, adding it remained a "safe travel destination".

More than 55 million people pass through Singapore's Changi airport every year. In the first half of this year, tourism arrivals topped 8 million, around 1 million more than a year earlier.

Malaysia has asked people visiting Singapore to use repellent and cover up to avoid mosquito bites. Tens of thousands of people travel between the two nations each day, by boat, air and across two land border crossings.

Both Malaysia and neighbouring Indonesia have stepped up protective measures following the Singapore outbreak, intensifying checks on people arriving from Singapore, introducing thermal scanners and posting paramedics at airports and border checkpoints.

Zika is carried by mosquitoes, which transmit the virus to humans, but a small number of cases of sexual transmission have been reported in the United States and elsewhere. A case of suspected transmission through a blood transfusion in Brazil has raised questions about other ways Zika may spread.

There is no vaccine or treatment for Zika, which is a close cousin of dengue and chikungunya and causes mild fever, rash and red eyes. An estimated 80 percent of people infected have no symptoms, however. </s> SINGAPORE, Aug 30 (Reuters) - The number of confirmed cases of Zika virus in Singapore rose to 82 on Tuesday, with some of the latest infections detected beyond the area of the initial outbreak.

Several countries advised pregnant women or those trying to conceive to avoid travelling to the city-state.

The mosquito-borne Zika virus was detected in Brazil last year and has since spread across the Americas. It poses a risk to pregnant women as it can cause severe birth defects. It has been linked in Brazil to more than 1,800 cases of microcephaly, a rare birth defect where babies are born with abnormally small heads and brains.

At least five of 26 new cases confirmed late on Tuesday were detected outside the initial cluster in the Aljunied area in the southeast of Singapore, the health ministry and National Environment Agency (NEA) said in a joint statement.

Australia, Taiwan and South Korea issued travel warnings, and Singapore advised pregnant women to take a free Zika test if they showed any symptoms or if their partners tested positive.

"This is regardless of whether they have been to Zika-affected areas," the statement said.

The outbreak and advisories come as the tourism industry in one of the world's busiest travel hubs already faces weak global economic growth. Singapore's Tourism Board said it was premature to consider any impact on the sector, adding it remained a "safe travel destination".

More than 55 million people pass through Singapore's Changi airport every year. In the first half of this year, tourism arrivals topped 8 million, around 1 million more than a year earlier.

Singapore reported its first case of locally-transmitted Zika at the weekend, and the number of confirmed infections has risen steadily since then. At least three dozen patients have made a full recovery.

Neighbouring Malaysia and Indonesia have stepped up protective measures, introducing thermal scanners at airports and border checkpoints with the island state.

Singapore residents responded to government calls to be vigilant and to take precautions against mosquito bites.

Online retailer Lazada Singapore said sales of insect repellents jumped fivefold in the past three days. FairPrice supermarkets and Watsons pharmacies said their sales of such products had doubled.

Most of the early infections were among foreign workers, hundreds of thousands of whom, mainly from the Asian sub-continent, work on Singapore's construction sites and in the marine sector.

The Singapore government has not said where the infected foreign workers are from. The foreign ministry directed queries to the health ministry, which did not respond to Reuters questions on the issue. The Ministry of Manpower also did not respond to a request for comment made outside working hours.

The High Commission of Bangladesh, which represents the largest community of foreign workers, said none of those infected were Bangladeshis, and the Thai foreign ministry said none were from Thailand. The embassies of China, India, Sri Lanka and Myanmar said they had not been notified by Singapore whether their citizens were among those infected.

Authorities inspected thousands of homes in seven parts of Singapore, including five foreign worker dormitories, spraying insecticide and removing potential mosquito breeding habitats.

The NEA has inspected about 5,000 premises in and around the initial outbreak area, issuing 400 notices to owners of buildings they could not access. The NEA can force entry into those premises if needed. </s> SINGAPORE (Reuters) - Confirmed cases of Zika virus in Singapore rose to 82 on Tuesday, as the United States joined a growing list of countries warning pregnant women or those trying to get pregnant to avoid travel to the city-state.

The mosquito-borne Zika virus, which has caused explosive outbreaks in the Americas and the Caribbean since late last year, poses a particular risk to pregnant women because it can cause microcephaly, a severe birth defect in which babies are born with abnormally small heads and underdeveloped brains.

On Tuesday, the United States warned pregnant women not to travel to Singapore, joining Australia, Taiwan and South Korea.

The warnings followed news that Zika transmission appears to be occurring outside of the original cluster, with at least five of 26 new cases confirmed late on Tuesday detected in the Aljunied area in the southeast of Singapore, the health ministry and National Environment Agency (NEA) said in a joint statement.

Singapore has advised pregnant women to take a free Zika test if they showed any symptoms or if their partners tested positive. “This is regardless of whether they have been to Zika-affected areas,” health officials said in a statement.

The outbreak and advisories come as the tourism industry in one of the world’s busiest travel hubs already faces weak global economic growth. Singapore’s Tourism Board said it was premature to consider any impact on the sector, adding it remained a “safe travel destination”.

Related Coverage CDC adds Zika-hit Singapore to interim travel guidance list

More than 55 million people pass through Singapore’s Changi airport every year. In the first half of this year, tourism arrivals topped 8 million, around 1 million more than a year earlier.

MOZZIE SPRAY SALES

Singapore reported its first case of locally-transmitted Zika at the weekend, and the number of confirmed infections has risen steadily since then. At least three dozen patients have made a full recovery.

Neighboring Malaysia and Indonesia have stepped up protective measures, introducing thermal scanners at airports and border checkpoints with the island state. Such measures, however, will only identify symptomatic cases of Zika, but only one in five people have symptoms of the virus, which include fever, rash, joint pain and pink eye.

Singapore residents responded to government calls to be vigilant and to take precautions against mosquito bites.

Online retailer Lazada Singapore said sales of insect repellents jumped five-fold in the past three days. FairPrice supermarkets and Watsons pharmacies said their sales of such products had doubled.

Airplane passengers walks through feverscan camera system used to detect human temperature shortly after arriving from Singapore at the Soekarno-Hatta airport in Jakarta, Indonesia, August 30, 2016. REUTERS/Beawiharta

Most of the early infections were among foreign workers, hundreds of thousands of whom, mainly from the Asian sub-continent, work on Singapore’s construction sites and in the marine sector.

The Singapore government has not said where the infected foreign workers are from. The foreign ministry directed queries to the health ministry, which did not respond to Reuters questions on the issue. The Ministry of Manpower also did not respond to a request for comment made outside working hours.

The High Commission of Bangladesh, which represents the largest community of foreign workers, said none of those infected were Bangladeshis, and the Thai foreign ministry said none were from Thailand. The embassies of China, India, Sri Lanka and Myanmar said they had not been notified by Singapore whether their citizens were among those infected.

Authorities inspected thousands of homes in seven parts of Singapore, including five foreign worker dormitories, spraying insecticide and removing potential mosquito breeding habitats.

The NEA has inspected about 5,000 premises in and around the initial outbreak area, issuing 400 notices to owners of buildings they could not access. The NEA can force entry into those premises if needed.

Zika was first discovered in Uganda in 1947. It caused clusters of human infections from the 1960s to 1980s across Africa and Asia, according to the World Health Organization.

The outbreak in the Americas was caused by a Zika strain from Asia, possibly carried to Brazil through travel to a sporting event. Many experts believe once infected, Zika produces lifelong immunity.

Slideshow (4 Images)

“Unfortunately, it is not clear the level of immunity that is currently in Asia,” said Alessandro Vespignani of Northeastern University in Boston.

WHO declared Zika a global health emergency because of its link with microcephaly. In Brazil, Zika has been linked to more than 1,800 cases of microcephaly. </s> JAKARTA, Indonesia (AP) — Indonesia is screening travelers from neighboring Singapore for the mosquito-borne Zika virus as the city-state reports a growing number of infections and its first case of a pregnant woman testing positive.

Indonesian Health Ministry spokesman Oscar Primadi said Thursday that health officials are recommending that the Foreign Ministry issue an advisory against nonessential travel to Singapore, particularly for pregnant women.

Singapore issued a statement on Wednesday evening saying it had identified 22 new Zika cases in one particular area of the city and its first case involving a pregnant woman.

Zika has mild effects for most people but doctors believe infection during pregnancy can result in babies with small heads, which is known as microcephaly, and other serious developmental disorders. Singapore had 155 cases as of Wednesday.

The U.S. Centers for Disease Control and Prevention is advising travelers to Singapore to take precautions such as protecting themselves against mosquito bites, and because the virus can also be sexually transmitted, to use condoms or not have sex.

Primadi said thermal imaging equipment to detect abnormal body temperatures was installed at eight Indonesian ports with routes serving Singapore, including the capital Jakarta's airport.

He said travelers will also be given a health questionnaire so they will recognize symptoms and know to immediately report to health authorities.

On Thursday, Malaysia's Health Ministry said a 58-year-old woman who traveled to Singapore had become that country's first Zika case.

Health Minister S. Subramaniam said the woman and her husband visited Singapore for three days from Aug. 19. The woman developed a rash a week after her return and later tested positive for Zika in her urine, he said. Her daughter in Singapore tested positive for Zika on Tuesday.

"We can conclude that it is rather easy to get infected by the virus when visiting places that has outbreak, including Singapore," he said. "Proactive action from the community can help stop the spread of Zika virus in Malaysia."

Subramaniam said the virus was believed to be imported from Singapore because the woman started experiencing symptoms on the same day as her daughter.

The ministry has started control activities such as eliminating mosquito breeding sites and fog spraying in her residential area and other places that the patient had visited.

Indonesia has not yet reported any local Zika infections but an Indonesian woman in Singapore is among those infected there.

Associated Press writer Eileen Ng in Kuala Lumpur, Malaysia contributed to this story. </s> SINGAPORE (AP) — Singapore said Tuesday it is investigating the severity of its locally transmitted Zika virus, amid a rising number of cases.

Researchers concluded last week that the strain of Zika found in two patients in Singapore was not from South America, but was similar to those found in the region decades ago.

“We cannot tell at this moment whether the viruses found here cause more or less severe disease than those in South America. Further research will be needed to shed light on this,” Health Minister Gan Kim Yong told Parliament.

Singapore announced its first confirmed Zika infection in May, with the virus imported by a 48-year-old man who had traveled to Brazil.

On Monday, the Ministry of Health and National Environment Agency confirmed four more locally transmitted cases, bringing the total to 333, including eight pregnant women.

“It is still early days to ascertain what the long-term trend of Zika infection will be,” Gan said, stopping short of labeling the outbreak an epidemic.

“Even if we can control the present outbreak, we will need to continue to guard against imported cases as the Zika virus is still circulating among many countries, including several in this region,” he said.

Last week, Gan told Channel NewsAsia that Singapore will no longer isolate all Zika patients, except when the infection is “severe or unless they have other conditions that require medical attention.”

The mosquito-borne Zika virus has mild effects on most people, but can be fatal for unborn children. Infection during pregnancy is believed to result in babies with small heads — a condition called microcephaly — and other brain defects.

Every day, about 850 workers in Singapore inspect homes and worksites for possible mosquito breeding grounds. From January to July, 748,000 inspections were conducted and more than 10,000 breeding habitats were destroyed, according to official statistics.

Despite government efforts, the island nation has been included in several travel advisories because of the Zika cases, with experts fearing this will cause a dip in tourism revenue. </s> Hong Kong (CNN) The Zika virus is on a rampage in Singapore, with 82 locally-transmitted cases confirmed late Tuesday by the country's Ministry of Health (MOH).

The MOH warns that the figures are likely set to rise, but why is Zika spreading so fast in the city state?

"The proportion of our population that are immune to the Zika virus is likely to be low in Singapore and if you don't have the immunity to provide the roadblocks, then it's likely that the virus will spread fast," Ooi Eng Eong, the deputy director of the Emerging Infectious Disease program at Duke-NUS Medical School in Singapore, told CNN.

Everything you need to know about Zika

Everything you need to know about Zika 01:42

Everything you need to know about Zika

The majority of reported cases are among foreign construction workers based in the residential Aljunied Crescent neighborhood in Singapore. Though cases were limited to this area on Monday, by late Tuesday the MOH reported 26 new cases that showed how the Zika virus had spread to nearby residential areas, raising concerns that the virus could travel even further afield.

While Malaysia and Indonesia announced they would be implementing additional passenger screening procedures at its airports, foreign ministries in the US, Australia, Taiwan and South Korea have all issued alerts, advising pregnant women against traveling to Singapore.

Singapore is known to suffer widely from dengue virus, a mosquito-borne tropical disease that triggers high fevers, headaches, vomiting and skin rashes in those infected.

In 2016, the MOH announced that it expected as many as 30,000 cases in the country.

Ooi explained that the Zika virus' rapid spread in Singapore was likely down to its similarities with the dengue virus.

"Zika is very closely related to dengue. It has all the genetic traits that would allow it to spread where dengue thrives -- the virus can infect and spread through the same Aedes aegypti mosquitoes that spread dengue virus," said Ooi.

With its 5.7 million-strong population packed mostly in crowded urban areas, containing Zika's spread in Singapore is a challenge.

"In Singapore, many people live in densely packed apartment blocks so it's easy for high numbers of people to get infected even if there are only a few mosquitoes flying around," explained Ooi.

As of August 29, Singapore's MOH had screened roughly 5,000 premises out of an estimated 6,000 in the Aljunied Crescent neighborhood to check for mosquito breeding grounds. So far, the agency has detected and destroyed 39 breeding habitats.

The MOH is also urging local residents to play an active role in stopping Zika's spread by distributing information leaflets and advising residents to apply repellent as a precaution.

Jaspar Fuk-Woo Chan, an infectious disease specialist and assistant professor at the University of Hong Kong, supported the MOH's efforts to reduce Zika's spread in Singapore.

"The government are making information on the Zika virus' spread readily available. They've also reacted very quickly to the first local cases by collecting information on the infected people," Chan told CNN.

He added, however, that it would take several weeks to grasp the extent of the outbreak. In the meantime, efforts to curb Zika's spread in the city state, he said, hinged on all citizens using insect repellent and making sure there were no potential mosquito breeding areas around their residential areas.

'Repellents are flying off the shelves'

In a joint statement released Wednesday, Singapore's MOH and the the Clinical Advisory Group (CAG) advised all pregnant women with symptoms of Zika, or with Zika-positive male partners to be tested for the infection.

But not every woman is letting the recent outbreak get to them.

"I'm conscious that I have to be more careful now," Su San, a 30-year-old mother trying for a second child, told CNN. "I'm applying ointments so that I don't get bitten, but I haven't put my plans to have another child on hold."

Rather than locking herself indoors, San said she would avoid areas like parks where mosquitoes were likely to be, and spend recreational time in libraries and museums instead.

For others, the Zika outbreak in Singapore has become an unlikely boon.

Theodore Khng, CEO of mosquito repellent startup Theo10, told CNN that sales of his natural deet-free product had tripled in the last three days.

Khng initially manufactured his product to combat mosquitoes carrying the dengue virus, but admitted that the recent Zika scare had boosted sales.

"People who have used the products before have been buying in bulk for others," said Khng. "The repellents are flying off the shelves." </s> Singapore has confirmed 41 cases of locally-transmitted Zika virus, mostly among foreign construction workers, and said it expected more cases to be identified.

All but seven of those infected have fully recovered, the health ministry and the National Environment Agency (NEA) said in a joint statement on Sunday. Those seven remain in hospital.

On Saturday, authorities had confirmed a 47-year-old Malaysian woman living in southeastern Singapore as the city-state's first case of a local transmission of the virus - which in Brazil has been linked to a rare birth defect.

The authorities said they tested 124 people, primarily foreign construction workers employed on a site in the same part of Singapore.

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That site has been ordered to halt work, and workers' dormitories are being inspected. Seventy-eight people tested negative and five cases were pending. Thirty-four patients had fully recovered.

Four Singaporean men had developed symptoms of the virus in the past week and were hospitalised on Saturday. It was not clear where the foreign workers were from or when their cases were detected. Singapore hosts a large contingent of workers from the Asian sub-continent.

None of those infected had travelled recently to Zika-affected areas. "This confirms that local transmission of Zika virus infection has taken place," the statement said.

The ministry "cannot rule out further community transmission since some of those tested positive also live or work in other parts of Singapore," the statement said. "We expect to identify more positive cases."

Singapore, a major regional financial centre and busy transit hub, which maintains a constant vigil against the mosquito-borne dengue virus, reported its first case of the Zika virus in May, brought in by a middle-aged man who had been to Brazil.

Singapore deployed around 200 NEA officers to clean drains and spray insecticide in the mainly residential area early on Sunday to counter mosquito breeding grounds, and volunteers and contractors handed out leaflets and insect repellent.

Zika, carried by some mosquitoes, was detected in Brazil last year and has since spread across the Americas. The virus poses a risk to pregnant women because it can cause severe birth defects. It has been linked in Brazil to more than 1,600 cases of microcephaly - where babies are born with small heads.

All medical services in Singapore had been alerted "to be extra vigilant" and immediately report any Zika-associated symptoms to the health ministry.

"I'm very scared of mosquitoes because they always seem to bite me, they never bite my husband," Janice, 31, who gave only her first name, told Reuters. "This concerns me because maybe in a couple of years I want to have another (child)."

Singapore said there were "ongoing local transmission" cases in Indonesia, Thailand and Vietnam. Other countries in the region to have detected the Zika virus since 2013 include Bangladesh, Cambodia, Laos, Malaysia, Maldives and the Philippines, according to the World Health Organisation (WHO).

Malaysia said on Sunday it stepped up surveillance at main transit points with Singapore - handing out leaflets on Zika prevention and having paramedics ready to handle visitors with potential symptoms of the virus.

In Thailand, where close to 100 cases of Zika have been recorded across 10 provinces this year, the Department of Disease Control (DDC) was screening athletes returning from the Olympic Games in Brazil, but was not otherwise changing its prevention measures.

"Every country in this region has Zika transmission cases," said Prasert Thongcharoen, an adviser to the DDC. "Thailand has, however, managed to contain the problem through early detection."

A foreign ministry spokesman said Indonesia was "following developments". Oskar Pribadi, a health ministry official, said there had been no recent Zika cases in the country.

Vietnam has to date reported three cases of locally-transmitted Zika infection.

The current strain of Zika sweeping through Latin America and the Caribbean originated in Asia, where people may have built up greater immunity.

The WHO has said there is strong scientific consensus that Zika can also cause Guillain-Barre, a rare neurological syndrome that causes temporary paralysis in adults. </s> Local administrative offices across the country have enacted measures against the spread of Zika virus after a slew of infections were reported.

Ang Thong Municipality has begun spraying against mosquitoes following news 94 people in the province of Bueng Kan contracted the disease with one still recovering.

According to Bueng Kan public health officer Dr. Wissanu Wittayabumrung, the 94 were found in 5 districts of the province. He affirmed 93 are completely recovered and that monitoring practices are being maintained in all susceptible areas.

Ang Thong public health officer Dr. Songwuth Hutamai let on that an order has been issued for all public health offices to enact precautionary measures against Zika, including in areas where no infections have yet been found.

The action comes ahead of a World Health Organization emergency meeting prompted by an outbreak of Zika in Singapore, which also led to travel warnings against the country being issued by nations such as Australia, Taiwan and the US.

While Zika is relatively minor among other viruses, it has been tied to a fetal condition seen when pregnant mothers contract the illness.
Australia, South Korea and Taiwan issue travel advisories concerning Singapore after cases of Zika virus infection in the city-state passes 50.