anchor
large_stringlengths 18
1.31k
| positive
large_stringlengths 0
284
| class
class label 3
classes |
|---|---|---|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. | microtubule cytoskeleton organization and biogenesis | 0biological_process
|
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. | nuclear interphase chromosome | 1cellular_component
|
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. | spliceosome assembly | 0biological_process
|
The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism. | allantoin metabolism | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. | allantoin breakdown | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. | allantoin catabolism | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. | allantoin degradation | 0biological_process
|
Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. | acetonitrilase activity | 2molecular_function
|
Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. | benzonitrilase activity | 2molecular_function
|
Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. | nitrile aminohydrolase activity | 2molecular_function
|
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. | mitochondrial division | 0biological_process
|
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. | mitochondrial proliferation | 0biological_process
|
Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome. | peroxisome targeting signal receptor | 2molecular_function
|
Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome. | PTS binding | 2molecular_function
|
Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome. | PTS receptor | 2molecular_function
|
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. | murein metabolic process | 0biological_process
|
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. | murein metabolism | 0biological_process
|
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. | peptidoglycan metabolism | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | glycan biosynthesis | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | glycan biosynthetic process | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide anabolism | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide biosynthesis | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide formation | 0biological_process
|
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide synthesis | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | multicellular organismal polysaccharide catabolic process | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide breakdown | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide catabolism | 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. | polysaccharide degradation | 0biological_process
|
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. | mitosis | 0biological_process
|
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. | M-phase | 0biological_process
|
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. | karyokinesis | 0biological_process
|
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. | cytokinesis after mitosis | 0biological_process
|
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae. | bud site selection/establishment of cell polarity | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | deadenylation-dependent mRNA decay | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA breakdown, deadenylation-dependent decay | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA catabolic process, deadenylation-dependent | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA catabolic process, deadenylylation-dependent | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA catabolism, deadenylation-dependent | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA catabolism, deadenylylation-dependent | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | mRNA degradation, deadenylation-dependent decay | 0biological_process
|
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. | nuclear mRNA catabolic process, deadenylation-dependent decay | 0biological_process
|
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. | 3\' to 5\' mRNA deadenylation | 0biological_process
|
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. | mRNA deadenylation | 0biological_process
|
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. | nuclear mRNA poly(A) tail shortening | 0biological_process
|
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. | deadenylation-dependent decapping of nuclear mRNA | 0biological_process
|
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. | deadenylylation-dependent decapping | 0biological_process
|
Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe2+-siderophore + electron acceptor. | ferric chelate reductase activity | 2molecular_function
|
Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe2+-siderophore + electron acceptor. | iron chelate reductase activity | 2molecular_function
|
The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi. | retrograde (vesicle recycling within Golgi) transport | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to active oxygen species | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to AOS | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to reactive oxidative species | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to reactive oxygen intermediate | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to ROI | 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. | response to ROS | 0biological_process
|
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner. | CDK holoenzyme | 1cellular_component
|
The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. | sulphite transport | 0biological_process
|
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. | vacuole, cell cycle-correlated morphology | 1cellular_component
|
A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. | vacuole, cell cycle-independent morphology | 1cellular_component
|
The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana. | lumen of vacuole with cell cycle-independent morphology | 1cellular_component
|
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory. | central bladder | 1cellular_component
|
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory. | central vacuole | 1cellular_component
|
The removal of a ubiquitin-like protein of the NEDD8 type from a protein. | cullin deneddylation | 0biological_process
|
Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. | binding to mRNA cap | 2molecular_function
|
Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. | mRNA cap binding | 2molecular_function
|
Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. | snRNA cap binding | 2molecular_function
|
The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans. | TREX complex | 1cellular_component
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | catalytic spliceosome assembly for second transesterification step | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | formation of catalytic spliceosome for second transesterification step | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | formation of catalytic U12-type spliceosome for second transesterification step | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | formation of catalytic U2-type spliceosome for second transesterification step | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | formation of spliceosomal A2-2 complex | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | formation of spliceosomal C1 complex | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | lariat formation, 5\'-splice site cleavage | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | spliceosomal A2-3 complex biosynthesis | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | spliceosomal A2-3 complex formation | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | spliceosomal C2 complex biosynthesis | 0biological_process
|
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. | spliceosomal C2 complex formation | 0biological_process
|
The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. | nuclear mRNA trans splicing, via spliceosome | 0biological_process
|
The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. | nuclear mRNA trans splicing, via U2-type spliceosome | 0biological_process
|
Splicing of RNA via a series of two transesterification reactions. | pre-mRNA splicing factor activity | 0biological_process
|
Splicing of RNA via a series of two transesterification reactions. | RNA splicing factor activity, transesterification mechanism | 0biological_process
|
Splicing of RNA via a series of two transesterification reactions. | spliceosomal catalysis | 0biological_process
|
Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure. | lariat RNA biosynthesis | 0biological_process
|
Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure. | lariat RNA formation | 0biological_process
|
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition. | alternative nuclear mRNA splicing, via spliceosome | 0biological_process
|
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition. | splice site selection | 0biological_process
|
The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome. | spliceosomal snRNP biogenesis | 0biological_process
|
Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. | nuclear mRNA 3\'-splice site recognition | 0biological_process
|
Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. | U12-type nuclear mRNA 3\'-splice site recognition | 0biological_process
|
Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. | U2-type nuclear mRNA 3\'-splice site recognition | 0biological_process
|
Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation. | 3\'-splice site cleavage, exon ligation | 0biological_process
|
Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. | mRNA splicing | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | nuclear mRNA 5\' splice site recognition | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | nuclear mRNA 5\'-splice site recognition | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | spliceosomal CC complex biosynthesis | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | spliceosomal CC complex formation | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | spliceosomal commitment complex biosynthesis | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | spliceosomal commitment complex formation | 0biological_process
|
Recognition of the intron 5'-splice site by components of the assembling spliceosome. | spliceosomal E complex biosynthesis | 0biological_process
|