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The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | histidine biosynthesis | 0biological_process
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The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | histidine biosynthetic process | 0biological_process
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The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | histidine formation | 0biological_process
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The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | histidine synthesis | 0biological_process
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Any complex formed of proteins that act in nucleotide-excision repair. | UvrB-UvrC complex | 1cellular_component
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Any complex formed of proteins that act in nucleotide-excision repair. | UvrBC complex | 1cellular_component
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One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p). | NEF3 complex | 1cellular_component
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A protein complex that possesses histone deacetylase activity. | HDAC complex | 1cellular_component
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A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I. | RNA polymerase I transcription factor complex | 1cellular_component
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | down regulation of global transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | down regulation of transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | down-regulation of global transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | down-regulation of transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | downregulation of global transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | downregulation of transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | inhibition of global transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | inhibition of transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | negative regulation of gene-specific transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | negative regulation of global transcription from Pol II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | negative regulation of transcription from Pol II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | negative regulation of transcription from RNA polymerase II promoter | 0biological_process
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Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. | negative regulation of transcription from RNA polymerase II promoter, global | 0biological_process
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A protein complex that possesses histone acetyltransferase activity. | histone acetylase complex | 1cellular_component
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | cell-cell adhesion involved in flocculation | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | co-flocculation | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | coflocculation | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | coflocculation via lectin-mannose interaction | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | coflocculation via protein-carbohydrate interaction | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | flocculation via cell wall protein-carbohydrate interaction | 0biological_process
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The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. | flocculation via extracellular polymer | 0biological_process
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A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. | establishment of spindle orientation during mitosis | 0biological_process
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A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. | establishment of spindle orientation involved in mitotic cell cycle | 0biological_process
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A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. | mitotic spindle orientation | 0biological_process
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A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. | orienting of mitotic spindle | 0biological_process
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A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. | alpha-1,6-mannosyltransferase complex | 1cellular_component
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The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER. | Golgi apparatus cis cisterna | 1cellular_component
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The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. | late Golgi | 1cellular_component
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The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | Golgi apparatus membrane | 1cellular_component
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | actin filament motor activity | 2molecular_function
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | actin-activated ATPase activity | 2molecular_function
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | actin-dependent ATPase activity | 2molecular_function
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | actin-filament motor activity | 2molecular_function
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | muscle motor activity | 2molecular_function
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A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. | myosin ATPase activity | 2molecular_function
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Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. | SNAP receptor binding | 2molecular_function
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The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically. | rRNA editing | 0biological_process
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A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. | histidyl-aspartyl phosphorelay | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | ERK/MAPK cascade | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAP kinase cascade | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAP kinase kinase kinase cascade | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAPK signal transduction | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAPK signaling | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAPK signalling | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAPKKK cascade | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | MAPKKK cascade during sporulation | 0biological_process
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An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. | mitogen-activated protein kinase cascade | 0biological_process
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Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. | 3\'-5\' exoribonuclease activity | 2molecular_function
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Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. | 3\'-5\'-exoribonuclease activity | 2molecular_function
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A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | eukaryotic exosome multienzyme ribonuclease complex | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | nuclear exosome (ribonuclease complex) | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | nuclear exosome multienzyme ribonuclease complex | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | cytoplasmic exosome (ribonuclease complex) | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | cytoplasmic exosome multienzyme ribonuclease complex | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | prokaryotic exosome multienzyme ribonuclease complex | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | exosome (ribonucleasease complex) | 1cellular_component
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A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. | exosome multienzyme ribonuclease complex | 1cellular_component
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Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor. | 18S rRNA dimethylase activity | 2molecular_function
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Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor. | dimethyladenosine transferase activity | 2molecular_function
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Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor. | S-adenosylmethionine-6-N\', N\'-adenosyl(rRNA) dimethyltransferase activity | 2molecular_function
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Binding to a DNA sequence encoding a ribosomal RNA. | ribosomal DNA binding | 2molecular_function
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The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3. | chromatin silencing at rDNA | 0biological_process
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The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3. | chromatin silencing at ribosomal DNA | 0biological_process
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The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3. | heterochromatic silencing at rDNA | 0biological_process
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The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3. | rDNA chromatin silencing | 0biological_process
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The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3. | rDNA heterochromatin assembly | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | mRNA breakdown, nonsense-mediated decay | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | mRNA catabolic process, nonsense-mediated | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | mRNA catabolism, nonsense-mediated | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | mRNA degradation, nonsense-mediated decay | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | nonsense-mediated mRNA decay | 0biological_process
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The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | nuclear mRNA catabolic process, nonsense-mediated decay | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | cell integrity MAPK pathway | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | cell wall integrity MAPK cascade | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | CWI pathway | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | Mpk1 cascade | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | Pmk1 MAPK cell integrity signaling | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway | 0biological_process
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A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | PMK1-MAPK signal transduction pathway | 0biological_process
|
A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs. | Slt2 cascade | 0biological_process
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Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. | polyubiquitin | 0biological_process
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Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. | protein polyubiquitinylation | 0biological_process
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Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. | protein polyubiquitylation | 0biological_process
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. | meiotic spindle organisation | 0biological_process
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. | meiotic spindle organization and biogenesis | 0biological_process
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. | meiotic spindle stabilization | 0biological_process
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. | spindle organization during meiosis | 0biological_process
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The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. | vacuolar hydrogen ion-transporting ATPase V0 domain | 1cellular_component
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The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. | vacuolar hydrogen ion-transporting ATPase V1 domain | 1cellular_component
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. | microtubule cytoskeleton organisation | 0biological_process
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