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JerrySiRi

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SWN_Bert_based_2019_2023_100

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[ { "contexts": [ "The differentially expressed genes (DEGs) associated with R‑CHOP therapy were identified using limma. " ], "name": "limma" } ]

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[ { "contexts": [ "Development of a CRISPR/Cas9-Based Tool for Gene Deletion in Issatchenkia orientalis. ", "Here we report that the autonomously replicating sequence (ARS) from Saccharomyces cerevisiae (ScARS) was functional for plasmid replication in I. orientalis, and the resulting episomal plasmid enabled efficient genome editing by the CRISPR/Cas9 system. ", "The optimized CRISPR/Cas9-based system employed a fusion RPR1'-tRNA promoter for single guide RNA (sgRNA) expression and could attain greater than 97% gene disruption efficiency for various gene targets. ", "The results outlined in this paper describe a stable episomal ARS-containing plasmid and the first CRISPR/Cas9-based system for gene disruptions in I. orientalis, paving the way for applying genome engineering and metabolic engineering strategies and tools in this microorganism for production of fuels and chemicals." ], "name": "CRISPR/Cas9" } ]

[ { "contexts": [ "Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed using Database for Annotation, Visualization and Integrated Discovery (DAVID). " ], "name": "DAVID" }, { "contexts": [ "The Gene Expression Profiling Interactive Analysis (GEPIA) was further performed in order to valid the mRNA levels of top5 up-regulated and top5 down-regualted DEGs, apart from exploring their association with survival rate as well as tumor stage. " ], "name": "GEPIA" } ]

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[ { "contexts": [ "Data-independent mass spectrometry enabled the unbiased quantitative characterization of 841 significant MWCNT-responses within an enriched peptide fraction, with 567 of these factors demonstrating significant correlation across animal-paired bronchoalveolar lavage and serum biofluids. " ], "name": "Data-independent mass spectrometry" } ]

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[ { "contexts": [ "They completed a questionnaire about family socio-demographic characteristics, HIV disclosure, and child demographic and clinical characteristics, as well as the Strengths and Difficulties Questionnaire, Life Stress Scale, Support Function Scale, and Impact on Family Scale which were pre-tested and translated into the local Chichewa language. ", "Using the newer band categorisations of the Strengths and Difficulties Questionnaire, parent version, 31% of primary caregivers reported that their child had a slightly raised to very high level of total difficulties. " ], "name": "Strengths and Difficulties Questionnaire" }, { "contexts": [ "They completed a questionnaire about family socio-demographic characteristics, HIV disclosure, and child demographic and clinical characteristics, as well as the Strengths and Difficulties Questionnaire, Life Stress Scale, Support Function Scale, and Impact on Family Scale which were pre-tested and translated into the local Chichewa language. " ], "name": "Life Stress Scale" }, { "contexts": [ "They completed a questionnaire about family socio-demographic characteristics, HIV disclosure, and child demographic and clinical characteristics, as well as the Strengths and Difficulties Questionnaire, Life Stress Scale, Support Function Scale, and Impact on Family Scale which were pre-tested and translated into the local Chichewa language. " ], "name": "Support Function Scale" }, { "contexts": [ "They completed a questionnaire about family socio-demographic characteristics, HIV disclosure, and child demographic and clinical characteristics, as well as the Strengths and Difficulties Questionnaire, Life Stress Scale, Support Function Scale, and Impact on Family Scale which were pre-tested and translated into the local Chichewa language. " ], "name": "Impact on Family Scale" } ]

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[ { "contexts": [ "mRNA sequence data from high‑risk WT and adjacent normal samples were downloaded from The Cancer Genome Atlas to screen for differentially expressed genes (DEGs) using R software. " ], "name": "R software" }, { "contexts": [ "The Search Tool for the Retrieval of Interacting Genes was used to construct a protein‑protein interaction network for the identified DEGs, and the hub genes of WGCNA modules were identified using the Cytohubb plugin with Cytoscape software. " ], "name": "Cytoscape software" } ]

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[ { "contexts": [ "A meta-analysis was conducted using Review Manager software to create forest plots and calculate odds ratios and mean differences.\n\n\n" ], "name": "Review Manager software" } ]

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[ { "contexts": [ "All statistical analyses were done using the Microsoft Excel and SPSS version 25.\n\n\n" ], "name": "Microsoft Excel" }, { "contexts": [ "All statistical analyses were done using the Microsoft Excel and SPSS version 25.\n\n\n" ], "name": "SPSS version 25" }, { "contexts": [ "Network analysis through VOSviewer was used for mapping the characteristics of the retrieved articles. " ], "name": "VOSviewer" } ]

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