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<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
D: interferon regulatory factor 1 (homo sapiens) (aka inte... | B |
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'type i interferon'. Answer using one of the provided options. | <Options>: A: ifn-alphaa (homo sapiens) (aka interferon alpha 2)
B: infe1 (homo sapiens) (interferon kappa (homo sapiens)) (aka interferon kappa)
C: ifn-e1 (homo sapiens) (aka interferon epsilon)
D: interferon (gallus gallus) (aka interferon)
E: interferon, alpha 1 (rattus norvegicus) (aka interferon, alpha 1)
F: ifn-a... | K |
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
B: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
C: cd8b2 (homo sapiens) (aka cd8b family member 2)
D: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
E: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
F: cd8a (hom... | D |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'interferon (ifn) consensus sequence-... | <Options>: A: interferon regulatory factor 6 (mus caroli) (aka interferon regulatory factor 6)
B: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
C: interferon regulatory factor 3 (homo sapiens) (aka interferon regulatory factor 3)
D: interferon regulatory factor 4 (homo sapiens) (aka... | F |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the prov... | <Options>: A: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
B: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
C: icsbp (mus musculus) (aka interferon regulatory factor 8)
D: interferon regulatory factor 5 (homo sapiens) (aka inte... | C |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'transcription factor'. Answer using ... | <Options>: A: transcription factor ec (xenopus tropicalis) (aka transcription factor ec)
B: transcription factor ec (mus musculus) (aka transcription factor ec)
C: transcription factor ec (gallus gallus) (aka transcription factor ec)
D: tcf-1 (homo sapiens) (hnf1 homeobox a (homo sapiens)) (aka hnf1 homeobox a)
E: tran... | K |
<Instruct>: Given the context 'In this study, we have characterized the phenotype and activation pattern of subsets of dendritic cells (DCs) in ICSBP(-/-) mice.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp (homo sapiens) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
D: interferon regulatory factor 2 binding protein 1... | B |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'ifn'. Answer using one of the provided op... | <Options>: A: ifnan (homo sapiens) (aka interferon lambda 4 (gene/pseudogene))
B: inf (homo sapiens) (aka cobalamin binding intrinsic factor)
C: ifnb (homo sapiens) (aka interferon beta 1)
D: ifna (homo sapiens) (interferon, type 1, cluster (homo sapiens)) (aka interferon, type 1, cluster)
E: ifn (xenopus laevis) (unch... | K |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided ... | <Options>: A: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
B: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
C: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
D: icsbp1 (mus musculus) (aka i... | D |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'cd11c'. Answer using one of the provided ... | <Options>: A: orphan cd11c (drosophila melanogaster) (aka ncrna)
B: cd11c (homo sapiens) (aka integrin subunit alpha x)
C: leukocyte receptor cluster member 1 (homo sapiens) (aka leukocyte receptor cluster member 1)
D: itgax (canis lupus familiaris) (aka integrin subunit alpha x)
E: cd11b (homo sapiens) (aka integrin s... | F |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'b220'. Answer using one of the provided o... | <Options>: A: cd45-ap (homo sapiens) (aka protein tyrosine phosphatase receptor type c associated protein)
B: protein tyrosine phosphatase, receptor type a (gallus gallus) (aka protein tyrosine phosphatase, receptor type a)
C: mb1 (homo sapiens) (cd79a molecule (homo sapiens)) (aka cd79a molecule)
D: cd45 (mus musculus... | D |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'ly6c'. Answer using one of the provided o... | <Options>: A: ly6c (mus musculus) (aka lymphocyte antigen 6 family member c1)
B: ly6s (homo sapiens) (aka lymphocyte antigen 6 family member s)
C: ly6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
D: ly6c2 (mus musculus) (aka lymphocyte antigen 6 family memberc2)
E: ly6l (mus musculus) (aka lymphocyte anti... | A |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'cd11b'. Answer using one of the provided ... | <Options>: A: cd11b (gallus gallus) (aka integrin, alpha d)
B: cd11b (bos taurus) (aka integrin subunit alpha m)
C: integrin alpha l (mus musculus) (aka integrin alpha l)
D: integrin subunit alpha l (homo sapiens) (aka integrin subunit alpha l)
E: mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integ... | H |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'cd11c'. Answer using one of the provided options. | <Options>: A: alpha7 (mus musculus) (integrin alpha 7 (mus musculus)) (aka integrin alpha 7)
B: itgax (mus musculus) (aka integrin alpha x)
C: cd103 (homo sapiens) (aka integrin subunit alpha e)
D: cd11a (mus musculus) (aka integrin alpha l)
E: cd1c (homo sapiens) (aka cd1c molecule)
F: leu1 (homo sapiens) (cd5 molecul... | B |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
B: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
C: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
D: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
E: ... | J |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'type i ifns'. Answer using one of the provided options. | <Options>: A: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
B: ifn-e1 (homo sapiens) (aka interferon epsilon)
C: ifn-alphai (homo sapiens) (interferon alpha 17 (homo sapiens)) (aka interferon alpha 17)
D: interferon alpha 1 (homo sapiens) (aka interferon alpha 1)
E: interferon omega 1 (homo sapiens) (aka inter... | K |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
B: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
C: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s h... | E |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
B: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
C: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
D: cd8beta (homo sapiens) (aka cd8 subunit beta)
E: cd8 subunit alpha... | F |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
B: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
C: cd8b family member 2 (homo sapiens) (aka cd8b family member 2)
D: cd8alpha (homo sapiens) (a... | H |
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
D: icsbp1 (xenopus laevis) (interferon regulator... | B |
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8b1 (homo sapiens) (aka cd8 subunit beta)
B: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
C: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
D: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s ... | E |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: icam-1 (canis lupus familiaris) (aka intercellular adhesion molecule 1)
B: intercellular adhesion molecule 1 (mus musculus) (aka intercellular adhesion molecule 1)
C: intercellular adhesion molecule 3 (homo sapiens) (aka intercellular adhesion molecule 3)
D: icam-4 (mus musculus) (aka intercellular adhesi... | B |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: cd40 (canis lupus familiaris) (aka cd40 molecule)
B: cd40l (homo sapiens) (aka cd40 ligand)
C: tnf receptor superfamily member 4 (homo sapiens) (aka tnf receptor superfamily member 4)
D: cd40 molecule (homo sapiens) (aka cd40 molecule)
E: p50 (mus musculus) (cd40 antigen (mus musculus)) (aka cd40 antigen)... | E |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: cd80 molecule l homeolog (xenopus laevis) (aka cd80 molecule l homeolog)
B: b7 (mus musculus) (cd86 antigen (mus musculus)) (aka cd86 antigen)
C: cd80 molecule (canis lupus familiaris) (aka cd80 molecule)
D: cd80 (oryctolagus cuniculus) (aka cd80 molecule)
E: bb1 (homo sapiens) (cd80 molecule (homo sapien... | J |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: t-lymphocyte activation antigen cd86 l homeolog (xenopus laevis) (aka t-lymphocyte activation antigen cd86 l homeolog)
B: cd86 antigen (mus musculus) (aka cd86 antigen)
C: bb1 (homo sapiens) (cd80 molecule (homo sapiens)) (aka cd80 molecule)
D: cd86 molecule (homo sapiens) (aka cd86 molecule)
E: cd86 mole... | B |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: ccr7 (mus musculus) (aka c-c motif chemokine receptor 7)
B: c-c motif chemokine receptor 7 (xenopus tropicalis) (aka c-c motif chemokine receptor 7)
C: cd191 (homo sapiens) (aka c-c motif chemokine receptor 1)
D: c-c motif chemokine receptor 7 (bos taurus) (aka c-c motif chemokine receptor 7)
E: c-c motif... | A |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: ccbp2 (homo sapiens) (atypical chemokine receptor 2 (homo sapiens)) (aka atypical chemokine receptor 2)
B: cc-ckr-2 (xenopus laevis) (chemokine (c-c motif) receptor 2 l homeolog (xenopus laevis)) (aka chemokine (c-c motif) receptor 2 l homeolog)
C: c-c motif chemokine receptor-like 2 (mus musculus) (aka c... | D |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct ... | <Options>: A: ccr3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: c-c motif chemokine receptor 6 (homo sapiens) (aka c-c motif chemokine receptor 6)
C: ccr-2a (homo sapiens) (aka c-c motif chemokine receptor 2)
D: ccr10 (homo sapiens) (c-c motif chemokine receptor 10 (homo sapiens)) (aka c-c motif chemokine rec... | F |
<Instruct>: Given the context 'In addition, these cells were unable to undergo full phenotypic activation upon in vitro culture in presence of maturation stimuli such as lipopolysaccharide or poly (I:C), which paralleled with lack of Toll-like receptor (TLR)3 mRNA expression.', select the correct biomedical concept cor... | <Options>: A: toll like receptor 3 (xenopus tropicalis) (aka toll like receptor 3)
B: toll3 (drosophila melanogaster) (aka mstprox)
C: toll like receptor 7 (homo sapiens) (aka toll like receptor 7)
D: toll like receptor 3 (canis lupus familiaris) (aka toll like receptor 3)
E: toll like receptor 3 (bos taurus) (aka toll... | F |
<Instruct>: Given the context 'Finally, cytokine expression pattern was also altered in ICSBP(-/-)', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (mus musculus) (aka interferon regulatory factor 8)
B: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
C: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
D: icsbp1 (xenopus tropic... | A |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'interleukin (il)-12p40'. Answer using one of the provided options. | <Options>: A: interleukin 12a (canis lupus familiaris) (aka interleukin 12a)
B: p40 (mus musculus) (interleukin 12b (mus musculus)) (aka interleukin 12b)
C: p600 (homo sapiens) (interleukin 13 (homo sapiens)) (aka interleukin 13)
D: p40 (mus musculus) (interleukin 9 (mus musculus)) (aka interleukin 9)
E: p40 (homo sapi... | B |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'il-15'. Answer using one of the provided options. | <Options>: A: interleukin-15 (gallus gallus) (aka interleukin 15)
B: interleukin 15-like (ovis aries) (aka interleukin 15-like)
C: interleukin 15 (ovis aries) (aka interleukin 15)
D: il-15 (xenopus laevis) (interleukin 15 s homeolog (xenopus laevis)) (aka interleukin 15 s homeolog)
E: il-15 (xenopus laevis) (interleuki... | G |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'il-4'. Answer using one of the provided options. | <Options>: A: interleukin 4 (gallus gallus) (aka interleukin 4)
B: il-4 (mus musculus) (aka interleukin 4)
C: interleukin 5 (homo sapiens) (aka interleukin 5)
D: il4 (canis lupus familiaris) (aka interleukin 4)
E: interleukin 4 (cricetulus griseus) (aka interleukin 4)
F: il-4 (homo sapiens) (aka interleukin 4)
G: inter... | B |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of ... | <Options>: A: icsbp1 (mus musculus) (aka interferon regulatory factor 8)
B: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
C: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
D: ilbp (homo sapiens) (aka fatty acid binding protein 6)
E: icsbp (homo sapiens) (aka interferon regulatory factor 8)
F:... | A |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of ... | <Options>: A: h-icsbp (homo sapiens) (aka interferon regulatory factor 8)
B: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
C: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
D: interferon regulatory factor 2 binding protei... | E |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of ... | <Options>: A: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
B: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
C: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
D: cd8 subunit alpha (mus musculus) (aka cd8 subunit alph... | D |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of ... | <Options>: A: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
B: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
C: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
D: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog... | G |
<Instruct>: Given the context 'Sarco(endo)plasmic reticulum Ca2+-ATPase-2 gene: structure and transcriptional regulation of the human gene.', select the correct biomedical concept corresponding to 'sarco(endo)plasmic reticulum ca2+-atpase-2'. Answer using one of the provided options. | <Options>: A: dd (homo sapiens) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
B: atp2b (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting,... | A |
<Instruct>: Given the context 'The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) belong to a family of active calcium transport enzymes encoded by the SERCA1, 2, and 3 genes.', select the correct biomedical concept corresponding to 'serca1, 2, and 3'. Answer using one of the provided options. | <Options>: A: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
B: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
C: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog (xenopus laevis)) (aka atpase, ca++... | B |
<Instruct>: Given the context 'In this study, we describe the complete structure of the human SERCA2 gene and its 5 -regulatory region.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
B: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
C: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog (xenopus laevis)) (aka atpase, c... | H |
<Instruct>: Given the context 'The hSERCA2 gene is located in chromosome 12 position q24.1 in Contig NT_009770.8, spans 70 kb, and is organized in 21 exons intervened by 20 introns.', select the correct biomedical concept corresponding to 'hserca2'. Answer using one of the provided options. | <Options>: A: cest-2.2 (caenorhabditis elegans) (aka carboxylesterase type b domain-containing protein)
B: establishment of sister chromatid cohesion n-acetyltransferase 2 (homo sapiens) (aka establishment of sister chromatid cohesion n-acetyltransferase 2)
C: ce-a2 (drosophila melanogaster) (aka cecropin a2)
D: tcea2 ... | K |
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept corresponding to 'serca2a'. Answer using one of the provided options. | <Options>: A: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
B: serca2b (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
C: serca3 (xenopus laevis) (atpase sarcoplasmi... | G |
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept corresponding to 'serca2b'. Answer using one of the provided options. | <Options>: A: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
B: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
C: serca1 (homo sapiens) (aka atpase sarco... | G |
<Instruct>: Given the context 'The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
B: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
C: serca2 (homo sapiens) (aka atpase sarco... | C |
<Instruct>: Given the context 'It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE).', select the correct biomedical concept corresponding to 'sp1'. Answer using one of the provided options. | <Options>: A: sp1 transcription factor (xenopus tropicalis) (aka sp1 transcription factor)
B: sp1-like factor for pairing sensitive-silencing (drosophila melanogaster) (aka sp1-like factor for pairing sensitive-silencing)
C: sp1 transcription factor s homeolog (xenopus laevis) (aka sp1 transcription factor s homeolog)
... | I |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'gata-4, -5, -6'. Answer using one of the provi... | <Options>: A: gata binding protein 4 (homo sapiens) (aka gata binding protein 4)
B: gata6 (xenopus laevis) (gata binding protein 6 s homeolog (xenopus laevis)) (aka gata binding protein 6 s homeolog)
C: gata binding protein 4 (mus musculus) (aka gata binding protein 4)
D: gata binding protein 4 (xenopus tropicalis) (ak... | K |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'nkx-2.5'. Answer using one of the provided opt... | <Options>: A: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog)
B: nkx-2.5 (xenopus tropicalis) (aka nk2 homeobox 5)
C: nkx-2.3b (xenopus laevis) (aka nk2 homeobox 3 l homeolog)
D: nkx-1.2 (mus musculus) (aka nk1 homeobox 2)
E: nkx-2.5 (mus musculus) (aka nk2 homeobox... | E |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'csx'. Answer using one of the provided options... | <Options>: A: csx (mus musculus) (aka nk2 homeobox 5)
B: csl (xenopus laevis) (small muscle protein x-linked l homeolog (xenopus laevis)) (aka small muscle protein x-linked l homeolog)
C: csx2 (homo sapiens) (aka nk2 homeobox 6)
D: csx1-a (xenopus tropicalis) (aka nk2 homeobox 5)
E: csx1 (schizosaccharomyces pombe) (ak... | A |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'otf-1'. Answer using one of the provided optio... | <Options>: A: otf-6 (mus musculus) (aka pou domain, class 3, transcription factor 1)
B: otf1 (homo sapiens) (aka pou class 2 homeobox 1)
C: otf3 (homo sapiens) (pou class 5 homeobox 1 (homo sapiens)) (aka pou class 5 homeobox 1)
D: pou1f1 (homo sapiens) (aka pou class 1 homeobox 1)
E: otf-7 (mus musculus) (aka pou doma... | B |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'srf'. Answer using one of the provided options... | <Options>: A: srf (drosophila melanogaster) (surf wings (drosophila melanogaster)) (aka surf wings)
B: serum response factor homolog (caenorhabditis elegans) (aka serum response factor homolog)
C: srf-3 (caenorhabditis elegans) (aka udp-galactose/udp-n-acetylglucosamine transporter srf-3)
D: srf (mus musculus) (aka ser... | E |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'ap-2'. Answer using one of the provided option... | <Options>: A: ap-1/2beta (drosophila melanogaster) (aka adaptor protein complex 1/2, beta subunit)
B: ap2 (drosophila melanogaster) (adaptor protein complex 2, sigma subunit (drosophila melanogaster)) (aka adaptor protein complex 2, sigma subunit)
C: transcription factor ap-2 beta (mus musculus) (aka transcription fact... | I |
<Instruct>: Given the context 'Upstream from position -1.5 kb, there is no significant homology among the SERCA2 genes cloned.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
B: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog (xenopus laevis... | D |
<Instruct>: Given the context 'In this study, we report the cloning of 2.4 kb of 5-regulatory region and demonstrate that the proximal promoter region is sufficient for expression in cardiac myocytes, and the region from -225 to -1232 bp contains regulatory DNA elements which down-regulate the expression of the SERCA2 ... | <Options>: A: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
B: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
C: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
D: serca2a (drosophila melanogaster... | E |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'nfkappab'. Answer... | <Options>: A: nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis)) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog)
B: nfkappab (drosophila melanogaster) (dorsal-related immunity factor (drosophila melanogaster)... | E |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'rage'. Answer usi... | <Options>: A: rage-1 (homo sapiens) (aka mok protein kinase)
B: rage (canis lupus familiaris) (advanced glycosylation end-product specific receptor (canis lupus familiaris)) (aka advanced glycosylation end-product specific receptor)
C: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (ratt... | J |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'receptor for adva... | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: advanced glycosylation end-product specific receptor (cricetulus griseus) (aka advanced glycosylation end-product specific receptor)
C: rage (su... | G |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'r... | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor... | C |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 's... | <Options>: A: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
B: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
E: s100 calcium binding protein ... | B |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 's... | <Options>: A: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
B: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
C: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
D: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
E: s100a6 (homo sapiens) (aka s100 calcium bi... | F |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'r... | <Options>: A: rage1 (xenopus laevis) (aka mok protein kinase l homeolog)
B: ragef2 (homo sapiens) (aka rap guanine nucleotide exchange factor 6)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: rage (canis lupus fa... | C |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'n... | <Options>: A: nf-kappa-b (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis)) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog)
B: nfkappab (drosophila melanogaster) (dorsal (drosophila melanogaster)) (aka dorsal)
C: nf-k... | I |
<Instruct>: Given the context 'Human umbilical vein endothelial cells (HUVEC) were preincubated for 72 h with AGE-albumin or unmodified albumin for control, whereas AGE-albumin induction resulted in an upregulation of RAGE.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provide... | <Options>: A: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sap... | C |
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a18 (homo sapiens) (aka hornerin)
B: s100a (homo sapiens) (aka s100 calcium binding protein a1)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8)
E: s100a12 (homo sapiens) (aka s100... | D |
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
C: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
D: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
E: s100a8 (homo sapiens) (aka s100 calcium binding protei... | A |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
B: s100al (homo sapiens) (aka sentan, cilia apical structure protein)
C: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
D: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
E: s100a3 (homo sapiens) (aka s100 calcium bin... | H |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
E: s100al (homo sapien... | B |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'il-6'. Answer using one of the provided options. | <Options>: A: interleukin 6 (canis lupus familiaris) (aka interleukin 6)
B: interleukin 6 (rattus norvegicus) (aka interleukin 6)
C: interleukin 6 (ovis aries) (aka interleukin 6)
D: cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens)) (aka lif interleukin 6 family cytokine)
E: hgf (homo sapiens) (inte... | E |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'icam-1'. Answer using one of the provided options. | <Options>: A: icam1 (oryctolagus cuniculus) (intercellular adhesion molecule-1 (oryctolagus cuniculus)) (aka intercellular adhesion molecule-1)
B: icam-4 (mus musculus) (aka intercellular adhesion molecule 4, landsteiner-wiener blood group)
C: intercellular adhesion molecule 1 (mus musculus) (aka intercellular adhesion... | I |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'vcam-1'. Answer using one of the provided options. | <Options>: A: vcam1 (bos taurus) (aka vascular cell adhesion molecule 1)
B: platelet and endothelial cell adhesion molecule 1 (homo sapiens) (aka platelet and endothelial cell adhesion molecule 1)
C: vascular cell adhesion molecule 1 (homo sapiens) (aka vascular cell adhesion molecule 1)
D: vascular cell adhesion molec... | C |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'mcp1'. Answer using one of the provided options. | <Options>: A: mcp-1 (caenorhabditis elegans) (aka gdp-d-glucose phosphorylase 1)
B: scya1 (homo sapiens) (aka c-c motif chemokine ligand 1)
C: mcp-2 (homo sapiens) (aka c-c motif chemokine ligand 8)
D: c-x-c motif chemokine ligand 1 (homo sapiens) (aka c-x-c motif chemokine ligand 1)
E: ncc-1 (homo sapiens) (aka c-c mo... | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a18 (homo sapiens) (aka hornerin)
E: s100a1 (homo sapiens) (aka s100 calcium binding protein a1)
F: s100a4 (hom... | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
D: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
E: s100a4 (homo sapiens)... | B |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a1'. Answer using one of the provided options. | <Options>: A: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
B: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
C: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
D: s100a (xenopus laevis) (s100 calcium binding protein a1 l homeolog (xenopus laevis)) (aka s100 calcium binding prot... | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100b'. Answer using one of the provided options. | <Options>: A: protein s100-b-like (xenopus laevis) (aka protein s100-b-like)
B: s100p (homo sapiens) (aka s100 calcium binding protein p)
C: s100l (homo sapiens) (aka s100 calcium binding protein a2)
D: s100b (gallus gallus) (aka s100 calcium binding protein b)
E: s100-alpha (homo sapiens) (aka s100 calcium binding pro... | J |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
B: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
C: s100a18 (homo sapiens) (aka hornerin)
D: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
E: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
F: s100-a8 (ho... | F |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
C: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
D: s100a (homo sapiens) (aka s100 calcium binding protein a1)
E: s100a (xenopus laevis) (s100 calcium binding protein ... | A |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 'p38'. Answer using one of the provided options. | <Options>: A: p38b (homo sapiens) (aka mitogen-activated protein kinase 11)
B: p38 (drosophila melanogaster) (p38b map kinase (drosophila melanogaster)) (aka p38b map kinase)
C: p38gamma (homo sapiens) (aka mitogen-activated protein kinase 12)
D: p38mapk (drosophila melanogaster) (p38a map kinase (drosophila melanogast... | E |
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of t... | <Options>: A: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
B: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8)
C: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
D: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
E: s100a4 (homo sapiens) (aka s1... | B |
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of t... | <Options>: A: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
D: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
E: s100a4 (homo sapiens) (aka ... | B |
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
B: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a18 (homo sapiens) (aka hornerin)
D: s100a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
E: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
F: s10... | A |
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a1 (homo sapiens) (aka s100 calcium binding protein a1)
B: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
C: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
D: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
E: s100 calcium binding protein a9 (homo sapiens)... | E |
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept corresponding to 'growth hormone'. Answer using one of the provided options. | <Options>: A: gh2 (homo sapiens) (aka growth hormone 2)
B: ghl (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: growth hormone 1 (rattus norvegicus) (aka growth hormone 1)
D: growth hormone (gallus gallus) (aka growth hormone)
E: ghn (xenopus laevis) (growth hormone 1... | F |
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: gh1-a (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
B: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
C: gh (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
D: growth hormone 1 (homo sapiens) (aka growt... | D |
<Instruct>: Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
B: gh1 (homo sapiens) (aka growth hormone 1)
C: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
D: ghl (homo sapiens) (aka growth hormone 2)
E: ghs (homo sapiens) (aka goldenhar syndrome)
F: gh-n (xenopus laevis) (growth hormone 1 s... | B |
<Instruct>: Given the context 'The aim of the study was to establish the complete map of GH1 gene SNPs in our control normal population and to analyse its association with adult height.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: ghs (homo sapiens) (aka goldenhar syndrome)
B: gh1-a (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
C: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
D: gh-n (homo sapiens) (aka growth hormone 1)
E:... | D |
<Instruct>: Given the context 'DESIGN, SUBJECTS AND MEASUREMENTS: A systematic GH1 gene analysis was designed in a control population of 307 adults of both sexes with height normally distributed within normal range for the same population: -2 standard deviation scores (SDS) to +2 SDS.', select the correct biomedical co... | <Options>: A: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
B: gh1-a (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
D: gha1 (homo sapiens) (aka prolactin)
E: gh1 (drosophila melanogaster) (aka mitoc... | F |
<Instruct>: Given the context 'This study established the GH1 gene sequence variation map in a normal adult height control population confirming the high density of SNPs in a relatively small gene.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: ghs (homo sapiens) (aka goldenhar syndrome)
B: gh1-b (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
D: gha1 (homo sapiens) (aka prolactin)
E: gh (homo sapiens) (growth hormone 1 (homo sapi... | E |
<Instruct>: Given the context 'Systematic GH1 gene analysis in patients with growth delay and suspected GH deficiency/insufficiency will clarify whether different SNP frequencies and/or the presence of different sequence changes may be associated with phenotypes in them.', select the correct biomedical concept correspo... | <Options>: A: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
B: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
C: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
D: gh1 (homo sapiens) (aka growth hormone 1)
E: gh1-b (xenopus laevis) (gr... | D |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ccr2'. Answer using one of the pro... | <Options>: A: c-c motif chemokine receptor-like 2 (mus musculus) (aka c-c motif chemokine receptor-like 2)
B: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2)
C: c-c motif chemokine receptor 2 (mus musculus) (aka c-c motif chemokine receptor 2)
D: mcp-1-r (xenopus laevis) (chemokine (c-c motif) receptor 2 s ho... | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ccr5'. Answer using one of the pro... | <Options>: A: c-c chemokine receptor type 5 (mus caroli) (aka c-c chemokine receptor type 5)
B: ckr5 (homo sapiens) (aka c-c motif chemokine receptor 5)
C: ccr5as (homo sapiens) (aka ccr5 antisense rna)
D: cc-ckr-7 (homo sapiens) (aka c-c motif chemokine receptor 7)
E: ccr5 (sus scrofa) (aka c-c motif chemokine recepto... | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'cox1'. Answer using one of the pro... | <Options>: A: cox1 (xenopus laevis) (cytochrome c oxidase subunit i (xenopus laevis)) (aka cytochrome c oxidase subunit i)
B: cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase i)
C: cox10 (homo sapiens) (aka cytochrome c oxidase assembl... | D |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'cox2'. Answer using one of the pro... | <Options>: A: cox2 (oryctolagus cuniculus) (aka cytochrome c oxidase subunit ii)
B: cox25 (homo sapiens) (aka cytochrome c oxidase assembly factor 3)
C: cox23 (homo sapiens) (aka coiled-coil-helix-coiled-coil-helix domain containing 7)
D: cox2 (drosophila melanogaster) (aka mitochondrial cytochrome c oxidase subunit ii... | G |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'crp'. Answer using one of the prov... | <Options>: A: crp-1 (caenorhabditis elegans) (aka cdc-42 related protein)
B: crp1 (mus musculus) (cysteine-rich protein 1 (mus musculus)) (aka cysteine-rich protein 1)
C: crp3 (homo sapiens) (cysteine and glycine rich protein 3 (homo sapiens)) (aka cysteine and glycine rich protein 3)
D: crp2 (homo sapiens) (cysteine r... | F |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'csf1'. Answer using one of the pro... | <Options>: A: csf2 (homo sapiens) (aka colony stimulating factor 2)
B: colony stimulating factor 1 (cricetulus griseus) (aka colony stimulating factor 1)
C: csf-3 (xenopus laevis) (colony stimulating factor 3 s homeolog (xenopus laevis)) (aka colony stimulating factor 3 s homeolog)
D: csf1 (gallus gallus) (aka colony s... | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'csf2'. Answer using one of the pro... | <Options>: A: colony stimulating factor 2 (canis lupus familiaris) (aka colony stimulating factor 2)
B: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
C: colony stimulating factor 2 (sus scrofa) (aka colony stimulating factor 2)
D: interleukin 2 (homo sapiens) (aka int... | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ifng'. Answer using one of the pro... | <Options>: A: ifn (xenopus laevis) (uncharacterized loc108702184 (xenopus laevis)) (aka uncharacterized loc108702184)
B: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
C: ifngm2 (homo sapiens) (aka interferon production regulator)
D: ifng (cricetulus griseus) (aka interferon gamma)
E: ifna5 (homo sapiens) (aka ... | G |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il1a'. Answer using one of the pro... | <Options>: A: il1a (canis lupus familiaris) (aka interleukin 1 alpha)
B: il1f11 (homo sapiens) (aka interleukin 33)
C: il-1h (homo sapiens) (aka interleukin 37)
D: il1-eta (homo sapiens) (aka interleukin 36 beta)
E: il1h1 (homo sapiens) (aka interleukin 36 gamma)
F: il1f2 (homo sapiens) (aka interleukin 1 beta)
G: il1l... | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il1b'. Answer using one of the pro... | <Options>: A: il1b (canis lupus familiaris) (aka interleukin 1 beta)
B: il1f11 (homo sapiens) (aka interleukin 33)
C: il1h2 (homo sapiens) (aka interleukin 36 beta)
D: il1f3 (homo sapiens) (aka interleukin 1 receptor antagonist)
E: il1f1 (homo sapiens) (aka interleukin 1 alpha)
F: il1hy2 (homo sapiens) (aka interleukin... | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il2'. Answer using one of the prov... | <Options>: A: interleukin 2 (homo sapiens) (aka interleukin 2)
B: il26 (homo sapiens) (aka interleukin 26)
C: il25 (homo sapiens) (interleukin 25 (homo sapiens)) (aka interleukin 25)
D: interleukin 2 (canis lupus familiaris) (aka interleukin 2)
E: il25 (homo sapiens) (myeloid derived growth factor (homo sapiens)) (aka ... | A |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il4'. Answer using one of the prov... | <Options>: A: interleukin-4 (gallus gallus) (aka interleukin 4)
B: il3 (homo sapiens) (aka interleukin 3)
C: interleukin 4 (ovis aries) (aka interleukin 4)
D: il-4 (homo sapiens) (aka interleukin 4)
E: il4 (bos taurus) (aka interleukin 4)
F: interleukin 4 (cricetulus griseus) (aka interleukin 4)
G: il-4 (canis lupus fa... | D |
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