{'id': 'HP_0010864', 'url': 'http://purl.obolibrary.org/obo/HP_0010864', 'lbl': 'Intellectual disability, severe', 'desc': 'label: Intellectual disability, severe\ndefinition : Severe mental retardation is defined as an intelligence quotient (IQ) in the range of 20-34.\nsynonyms :Early and severe mental retardation; Intellectual disability, severe; Mental retardation, severe; Severe mental retardation\n'}


{'id': 'HP_0010865', 'url': 'http://purl.obolibrary.org/obo/HP_0010865', 'lbl': 'Oppositional defiant disorder', 'desc': "label: Oppositional defiant disorder\ndefinition : An enduring pattern of uncooperative, defiant, and hostile behavior toward authority figures that does not involve major antisocial violations, is not accounted for by the child's developmental stage, and results in significant functional impairment. A certain level of oppositional behavior is common in children and adolescents.\nsynonyms :\n"}


{'id': 'HP_0010866', 'url': 'http://purl.obolibrary.org/obo/HP_0010866', 'lbl': 'Abdominal wall defect', 'desc': 'label: Abdominal wall defect\ndefinition : An incomplete closure of the abdominal wall.\nsynonyms :Abdominal wall defect; Congenital anterior abdominal wall defect\n'}


{'id': 'HP_0010867', 'url': 'http://purl.obolibrary.org/obo/HP_0010867', 'lbl': 'Dyssynergia', 'desc': 'label: Dyssynergia\ndefinition : A type of ataxia characterized by the impairment of the ability to smoothly perform the elements of a voluntary movement in the appropriate order and speed. With dyssynergia, a voluntary movement appears broken down into its component parts.\nsynonyms :\n'}


{'id': 'HP_0010868', 'url': 'http://purl.obolibrary.org/obo/HP_0010868', 'lbl': 'Ocular dyssynergia', 'desc': 'label: Ocular dyssynergia\ndefinition : A type of dyssynergia affecting eye movements and characterized by the inability to smoothly follow a visual target across the visual field.\nsynonyms :\n'}


{'id': 'HP_0010869', 'url': 'http://purl.obolibrary.org/obo/HP_0010869', 'lbl': 'Asynergia', 'desc': 'label: Asynergia\ndefinition : A type of dyssynergy characterized by the lack of the ability to smoothly perform the elements of a voluntary movement in the appropriate order and speed.\nsynonyms :\n'}


{'id': 'HP_0010871', 'url': 'http://purl.obolibrary.org/obo/HP_0010871', 'lbl': 'Sensory ataxia', 'desc': 'label: Sensory ataxia\ndefinition : Incoordination of movement caused by a deficit in the sensory nervous system. Sensory ataxia can be distinguished from cerebellar ataxia by asking the patient to close his or her eyes. Persons with cerebellar ataxia show only a minimal worsening of symptoms, whereas persons with sensory ataxia show a marked worsening of symptoms.\nsynonyms :Afferent ataxia; Ataxia, sensory; Spinal ataxia\n'}


{'id': 'HP_0010872', 'url': 'http://purl.obolibrary.org/obo/HP_0010872', 'lbl': 'T-wave inversion', 'desc': 'label: T-wave inversion\ndefinition : An inversion of the T-wave (which is normally positive).\nsynonyms :EKG: T-wave inversion\n'}


{'id': 'HP_0010873', 'url': 'http://purl.obolibrary.org/obo/HP_0010873', 'lbl': 'Cervical spinal cord atrophy', 'desc': 'label: Cervical spinal cord atrophy\ndefinition : Atrophy of the cervical segment of the spinal cord.\nsynonyms :\n'}


{'id': 'HP_0010874', 'url': 'http://purl.obolibrary.org/obo/HP_0010874', 'lbl': 'Tendon xanthomatosis', 'desc': 'label: Tendon xanthomatosis\ndefinition : The presence of xanthomas (intra-and extra-cellular accumulations of cholesterol) extensor tendons (typically over knuckles, Achilles tendon, knee, and elbows).\nsynonyms :Tendon xanthomas\n'}


{'id': 'HP_0010875', 'url': 'http://purl.obolibrary.org/obo/HP_0010875', 'lbl': 'Chaddock reflex', 'desc': 'label: Chaddock reflex\ndefinition : A diagnostic reflex elicited by stimulation of the skin over the surface of the lateral malleolus of the foot. The Chaddock refelx is present if there is extension of one or more or all of the toes with or without fanning of them when the external inframalleolar skin is stimulated. The Chaddock sign, similar to the Babinski sign, is taken to be an indication of disease of the spinocortical (pyramidal) tract.\nsynonyms :\n'}


{'id': 'HP_0010876', 'url': 'http://purl.obolibrary.org/obo/HP_0010876', 'lbl': 'Abnormal circulating protein concentration', 'desc': 'label: Abnormal circulating protein concentration\ndefinition : An abnormal level of a circulating protein in the blood.\nsynonyms :Abnormal circulating protein level; Abnormality of circulating protein level; Blood protein disease; Serum protein abnormality\n'}


{'id': 'HP_0010877', 'url': 'http://purl.obolibrary.org/obo/HP_0010877', 'lbl': 'Monocular strabismus', 'desc': "label: Monocular strabismus\ndefinition : A type of strabismus in which the fixating eye is always the same one, while the other eye is constantly deviated. Monocular strabismus is to be distinguished from alternating strabismus, in which either of the eyes 'squints' at different times.\nsynonyms :Unilateral strabismus\n"}


{'id': 'HP_0010878', 'url': 'http://purl.obolibrary.org/obo/HP_0010878', 'lbl': 'Fetal cystic hygroma', 'desc': 'label: Fetal cystic hygroma\ndefinition : The presence during the prenatal period of a cystic mass with multiple septa with multiple, asymmetric, thin-walled cysts near the posterior aspect of the neck. Fetal cystic hygroma can be defined as nuchal translucency with or without septations measuring greater than 3.0 mm. Increased NT refers to a measurement above the 95th centile, and the term is used irrespective of whether the collection of fluid is septated or not, and whether it is confined to the neck or envelopes the whole fetus. After 14 weeks, increased NT usually resolves, but in some cases it evolves into nuchal edema or cystic hygromas.\nsynonyms :Foetal cystic hygroma\n'}


{'id': 'HP_0010879', 'url': 'http://purl.obolibrary.org/obo/HP_0010879', 'lbl': 'Postnatal cystic hygroma', 'desc': 'label: Postnatal cystic hygroma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0010880', 'url': 'http://purl.obolibrary.org/obo/HP_0010880', 'lbl': 'Increased nuchal translucency', 'desc': 'label: Increased nuchal translucency\ndefinition : Nuchal translucency is the sonographic appearance of subcutaneous accumulation of liquid in the back of the fetal neck in the first trimester of pregnancy (11-14 gestational weeks of pregnancy).\nsynonyms :\n'}


{'id': 'HP_0010881', 'url': 'http://purl.obolibrary.org/obo/HP_0010881', 'lbl': 'Abnormality of the umbilical cord', 'desc': 'label: Abnormality of the umbilical cord\ndefinition : An abnormality of the umbilical cord, which is the cord connecting the developing embryo or fetus to the placenta.\nsynonyms :Umbilical cord issue\n'}


{'id': 'HP_0010882', 'url': 'http://purl.obolibrary.org/obo/HP_0010882', 'lbl': 'Pulmonary valve atresia', 'desc': 'label: Pulmonary valve atresia\ndefinition : A congenital disorder of the pulmonary valve in which the orifice of the valve fails to develop.\nsynonyms :\n'}


{'id': 'HP_0010883', 'url': 'http://purl.obolibrary.org/obo/HP_0010883', 'lbl': 'Aortic valve atresia', 'desc': 'label: Aortic valve atresia\ndefinition : A congenital disorder of the aortic valve in which the orifice of the valve fails to develop.\nsynonyms :Aortic atresia\n'}


{'id': 'HP_0010884', 'url': 'http://purl.obolibrary.org/obo/HP_0010884', 'lbl': 'Acromelia', 'desc': 'label: Acromelia\ndefinition : Shortening of the extremities affecting primarily the distal parts of the limbs (hands and feet) in relation to the other segments of the limbs.\nsynonyms :\n'}


{'id': 'HP_0010885', 'url': 'http://purl.obolibrary.org/obo/HP_0010885', 'lbl': 'Avascular necrosis', 'desc': 'label: Avascular necrosis\ndefinition : A disease where there is cellular death (necrosis) of bone components due to interruption of the blood supply.\nsynonyms :Aseptic bone necrosis; Aseptic necrosis; Bone infarction; Death of bone due to decreased blood supply; Ischaemic bone necrosis; Ischemic bone necrosis; Osteochondronecrosis; Osteonecrosis\n'}


{'id': 'HP_0010886', 'url': 'http://purl.obolibrary.org/obo/HP_0010886', 'lbl': 'Osteochondritis dissecans', 'desc': 'label: Osteochondritis dissecans\ndefinition : A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage.\nsynonyms :Osteochondrosis dissecans\n'}


{'id': 'HP_0010888', 'url': 'http://purl.obolibrary.org/obo/HP_0010888', 'lbl': 'Morbus Koehler', 'desc': 'label: Morbus Koehler\ndefinition : Morbus Koehler is a Juvenile aseptic necrosis affecting the Os naviculare pedis.\nsynonyms :\n'}


{'id': 'HP_0010889', 'url': 'http://purl.obolibrary.org/obo/HP_0010889', 'lbl': 'Morbus Kienboeck', 'desc': "label: Morbus Kienboeck\ndefinition : Morbus Kienboeck is a Juvenile aseptic necrosis affecting the Os lunatum.\nsynonyms :Kienboeck's disease; Kienböck's disease; Lunatomalacia\n"}


{'id': 'HP_0010890', 'url': 'http://purl.obolibrary.org/obo/HP_0010890', 'lbl': 'Morbus Osgood-Schlatter', 'desc': 'label: Morbus Osgood-Schlatter\ndefinition : Morbus Osgood-Schlatter is a Juvenile aseptic necrosis affecting the Tuberositas tibiae.\nsynonyms :Osgood Schlatter disease\n'}


{'id': 'HP_0010891', 'url': 'http://purl.obolibrary.org/obo/HP_0010891', 'lbl': 'Morbus Scheuermann', 'desc': "label: Morbus Scheuermann\ndefinition : A developmental growth retardation of the vertebral end plates that may lead to secondary destruction of the vertebral end plates and protrusion of the nucleus pulposus into the vertebral body (so called Schmorl's nodes as seen on x-rays).\nsynonyms :Calve disease; Juvenile osteochondrosis of the spine; Scheuermann disease; Scheuermann kyphosis; Sherman's Disease\n"}


{'id': 'HP_0010892', 'url': 'http://purl.obolibrary.org/obo/HP_0010892', 'lbl': 'Abnormal circulating branched chain amino acid concentration', 'desc': 'label: Abnormal circulating branched chain amino acid concentration\ndefinition : Any deviation from the normal concentration of a branched chain family amino acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010893', 'url': 'http://purl.obolibrary.org/obo/HP_0010893', 'lbl': 'Abnormal circulating phenylalanine concentration', 'desc': 'label: Abnormal circulating phenylalanine concentration\ndefinition : Any deviation from the normal concentration of phenylalanine in the blood circulation.\nsynonyms :Abnormality of phenylalanine metabolism\n'}


{'id': 'HP_0010894', 'url': 'http://purl.obolibrary.org/obo/HP_0010894', 'lbl': 'Abnormal circulating serine family amino acid concentration', 'desc': 'label: Abnormal circulating serine family amino acid concentration\ndefinition : Any deviation from the normal concentration of a serine family amino acid in the blood circulation.\nsynonyms :Abnormality of serine family amino acid metabolism\n'}


{'id': 'HP_0010895', 'url': 'http://purl.obolibrary.org/obo/HP_0010895', 'lbl': 'Abnormal circulating glycine concentration', 'desc': 'label: Abnormal circulating glycine concentration\ndefinition : Any deviation from the normal concentration of glycine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010896', 'url': 'http://purl.obolibrary.org/obo/HP_0010896', 'lbl': 'Hypersarcosinemia', 'desc': 'label: Hypersarcosinemia\ndefinition : An elevated plasma concentration of sarcosine.\nsynonyms :High plasma sarcosine levels\n'}


{'id': 'HP_0010897', 'url': 'http://purl.obolibrary.org/obo/HP_0010897', 'lbl': 'Hypersarcosinuria', 'desc': 'label: Hypersarcosinuria\ndefinition : An elevated urinary concentration of sarcosine.\nsynonyms :High urine sarcosine levels\n'}


{'id': 'HP_0010898', 'url': 'http://purl.obolibrary.org/obo/HP_0010898', 'lbl': 'Abnormal circulating sarcosine concentration', 'desc': 'label: Abnormal circulating sarcosine concentration\ndefinition : An deviation from the normal concentration of sarcosine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010899', 'url': 'http://purl.obolibrary.org/obo/HP_0010899', 'lbl': 'Abnormal circulating aspartate family amino acid concentration', 'desc': 'label: Abnormal circulating aspartate family amino acid concentration\ndefinition : Any deviation from the normal concentration of an aspartate family amino acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010900', 'url': 'http://purl.obolibrary.org/obo/HP_0010900', 'lbl': 'Abnormal circulating threonine concentration', 'desc': 'label: Abnormal circulating threonine concentration\ndefinition : Any deviation from the normal concentration of threonine in the blood circulation.\nsynonyms :Abnormality of threonine metabolism\n'}


{'id': 'HP_0010901', 'url': 'http://purl.obolibrary.org/obo/HP_0010901', 'lbl': 'Abnormal circulating methionine concentration', 'desc': 'label: Abnormal circulating methionine concentration\ndefinition : Any deviation from the normal concentration of methionine in the blood circulation.\nsynonyms :Abnormality of methionine metabolism\n'}


{'id': 'HP_0010902', 'url': 'http://purl.obolibrary.org/obo/HP_0010902', 'lbl': 'Abnormal circulating glutamine family amino acid concentration', 'desc': 'label: Abnormal circulating glutamine family amino acid concentration\ndefinition : Any deviation from the normal concentration of a glutamine family amino acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010903', 'url': 'http://purl.obolibrary.org/obo/HP_0010903', 'lbl': 'Abnormal circulating glutamine concentration', 'desc': 'label: Abnormal circulating glutamine concentration\ndefinition : Any deviation from the normal concentration of glutamine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010904', 'url': 'http://purl.obolibrary.org/obo/HP_0010904', 'lbl': 'Abnormal circulating histidine concentration', 'desc': 'label: Abnormal circulating histidine concentration\ndefinition : An abnormality of a histidine metabolic process.\nsynonyms :Abnormality of histidine metabolism\n'}


{'id': 'HP_0010905', 'url': 'http://purl.obolibrary.org/obo/HP_0010905', 'lbl': 'obsolete Abnormality of histidine metabolism', 'desc': 'label: obsolete Abnormality of histidine metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0010906', 'url': 'http://purl.obolibrary.org/obo/HP_0010906', 'lbl': 'Hyperhistidinemia', 'desc': 'label: Hyperhistidinemia\ndefinition : An increased concentration of histidine in the blood.\nsynonyms :High blood histidine level; Histidinemia\n'}


{'id': 'HP_0010907', 'url': 'http://purl.obolibrary.org/obo/HP_0010907', 'lbl': 'Abnormal circulating proline concentration', 'desc': 'label: Abnormal circulating proline concentration\ndefinition : Any deviation from the normal concentration of proline or a proline metabolite in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010908', 'url': 'http://purl.obolibrary.org/obo/HP_0010908', 'lbl': 'Abnormal circulating lysine concentration', 'desc': 'label: Abnormal circulating lysine concentration\ndefinition : Any deviation from the normal concentration of lysine in the blood circulation.\nsynonyms :Abnormality of lysine metabolism\n'}


{'id': 'HP_0010909', 'url': 'http://purl.obolibrary.org/obo/HP_0010909', 'lbl': 'Abnormal circulating arginine concentration', 'desc': 'label: Abnormal circulating arginine concentration\ndefinition : Any deviation from the normal concentration of arginine in the blood circulation.\nsynonyms :Abnormality of arginine metabolism\n'}


{'id': 'HP_0010910', 'url': 'http://purl.obolibrary.org/obo/HP_0010910', 'lbl': 'Hypervalinemia', 'desc': 'label: Hypervalinemia\ndefinition : An increased concentration of valine in the blood.\nsynonyms :High blood valine concentration\n'}


{'id': 'HP_0010911', 'url': 'http://purl.obolibrary.org/obo/HP_0010911', 'lbl': 'Hyperleucinemia', 'desc': 'label: Hyperleucinemia\ndefinition : An increased concentration of leucine in the blood.\nsynonyms :High blood leucine concentration\n'}


{'id': 'HP_0010912', 'url': 'http://purl.obolibrary.org/obo/HP_0010912', 'lbl': 'Abnormal circulating isoleucine concentration', 'desc': 'label: Abnormal circulating isoleucine concentration\ndefinition : Any deviation from the normal concentration of isoleucine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010913', 'url': 'http://purl.obolibrary.org/obo/HP_0010913', 'lbl': 'Hyperisoleucinemia', 'desc': 'label: Hyperisoleucinemia\ndefinition : An increased concentration of isoleucine in the blood.\nsynonyms :High blood isoleucine concentration\n'}


{'id': 'HP_0010914', 'url': 'http://purl.obolibrary.org/obo/HP_0010914', 'lbl': 'Abnormal circulating valine concentration', 'desc': 'label: Abnormal circulating valine concentration\ndefinition : Any deviation from the normal circulation of valine in the blood circulation.\nsynonyms :Abnormality of valine metabolism\n'}


{'id': 'HP_0010915', 'url': 'http://purl.obolibrary.org/obo/HP_0010915', 'lbl': 'Abnormal circulating pyruvate family amino acid concentration', 'desc': 'label: Abnormal circulating pyruvate family amino acid concentration\ndefinition : An abnormality of a pyruvate family amino acid metabolic process.\nsynonyms :Abnormality of pyruvate family amino acid metabolism\n'}


{'id': 'HP_0010916', 'url': 'http://purl.obolibrary.org/obo/HP_0010916', 'lbl': 'Abnormal circulating alanine concentration', 'desc': 'label: Abnormal circulating alanine concentration\ndefinition : An abnormality of an alanine metabolic process.\nsynonyms :Abnormality of alanine metabolism\n'}


{'id': 'HP_0010917', 'url': 'http://purl.obolibrary.org/obo/HP_0010917', 'lbl': 'Abnormal circulating tyrosine concentration', 'desc': 'label: Abnormal circulating tyrosine concentration\ndefinition : Any deviation from the normal concentration of tyrosine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010918', 'url': 'http://purl.obolibrary.org/obo/HP_0010918', 'lbl': 'Abnormal circulating cysteine concentration', 'desc': 'label: Abnormal circulating cysteine concentration\ndefinition : An abnormality of a cysteine metabolic process.\nsynonyms :\n'}


{'id': 'HP_0010919', 'url': 'http://purl.obolibrary.org/obo/HP_0010919', 'lbl': 'Abnormal circulating homocysteine concentration', 'desc': 'label: Abnormal circulating homocysteine concentration\ndefinition : An abnormality of a homocysteine metabolic process.\nsynonyms :\n'}


{'id': 'HP_0010920', 'url': 'http://purl.obolibrary.org/obo/HP_0010920', 'lbl': 'Zonular cataract', 'desc': 'label: Zonular cataract\ndefinition : Zonular cataracts are defined to be cataracts that affect specific regions of the lens.\nsynonyms :\n'}


{'id': 'HP_0010921', 'url': 'http://purl.obolibrary.org/obo/HP_0010921', 'lbl': 'Coralliform cataract', 'desc': "label: Coralliform cataract\ndefinition : A 'coral-like' pattern of opacity in the lens of the eye. That is, a cataract with an irregular, stellate form.\nsynonyms :\n"}


{'id': 'HP_0010922', 'url': 'http://purl.obolibrary.org/obo/HP_0010922', 'lbl': 'Membranous cataract', 'desc': 'label: Membranous cataract\ndefinition : A form of cataract in which the lens substance has shrunk, leaving a collapsed, flattened capsule with little or no cortex or epithelium on the lens.\nsynonyms :\n'}


{'id': 'HP_0010923', 'url': 'http://purl.obolibrary.org/obo/HP_0010923', 'lbl': 'Anterior subcapsular cataract', 'desc': "label: Anterior subcapsular cataract\ndefinition : A type of cataract affecting the anterior pole of lens immediately adjacent to ('beneath') the lens capsule.\nsynonyms :\n"}


{'id': 'HP_0010924', 'url': 'http://purl.obolibrary.org/obo/HP_0010924', 'lbl': 'Posterior cortical cataract', 'desc': 'label: Posterior cortical cataract\ndefinition : A cataract that affects the posterior part of the cortex of the lens.\nsynonyms :\n'}


{'id': 'HP_0010925', 'url': 'http://purl.obolibrary.org/obo/HP_0010925', 'lbl': 'Nuclear punctate cataract', 'desc': 'label: Nuclear punctate cataract\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0010926', 'url': 'http://purl.obolibrary.org/obo/HP_0010926', 'lbl': 'Aculeiform cataract', 'desc': 'label: Aculeiform cataract\ndefinition : A kind of nuclear cataract characterized by fiberglasslike or needlelike crystals projecting in different directions, through or close to the axial region of the lens.\nsynonyms :Fasciculiform cataract; Frosted cataract; Needle-shaped cataract\n'}


{'id': 'HP_0010927', 'url': 'http://purl.obolibrary.org/obo/HP_0010927', 'lbl': 'Abnormal blood inorganic cation concentration', 'desc': 'label: Abnormal blood inorganic cation concentration\ndefinition : An abnormality of divalent inorganic cation homeostasis.\nsynonyms :Abnormality of divalent inorganic cation homeostasis\n'}


{'id': 'HP_0010928', 'url': 'http://purl.obolibrary.org/obo/HP_0010928', 'lbl': 'obsolete Increased urinary orotic acid concentration', 'desc': 'label: obsolete Increased urinary orotic acid concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0010929', 'url': 'http://purl.obolibrary.org/obo/HP_0010929', 'lbl': 'Abnormal blood cation concentration', 'desc': 'label: Abnormal blood cation concentration\ndefinition : An abnormality of cation homeostasis.\nsynonyms :Abnormality of cation homeostasis\n'}


{'id': 'HP_0010930', 'url': 'http://purl.obolibrary.org/obo/HP_0010930', 'lbl': 'Abnormal blood monovalent inorganic cation concentration', 'desc': 'label: Abnormal blood monovalent inorganic cation concentration\ndefinition : An abnormality of monovalent inorganic cation homeostasis.\nsynonyms :Abnormality of monovalent inorganic cation homeostasis\n'}


{'id': 'HP_0010931', 'url': 'http://purl.obolibrary.org/obo/HP_0010931', 'lbl': 'Abnormal blood sodium concentration', 'desc': 'label: Abnormal blood sodium concentration\ndefinition : An abnormal concentration of sodium.\nsynonyms :Abnormal blood Na+ levels; Abnormal circulating Na concentration; Abnormality of sodium homeostasis\n'}


{'id': 'HP_0010932', 'url': 'http://purl.obolibrary.org/obo/HP_0010932', 'lbl': 'Abnormal circulating nucleobase concentration', 'desc': 'label: Abnormal circulating nucleobase concentration\ndefinition : An abnormality of a nucleobase metabolic process.\nsynonyms :Abnormal nucleoside levels\n'}


{'id': 'HP_0010933', 'url': 'http://purl.obolibrary.org/obo/HP_0010933', 'lbl': 'Hyperxanthinemia', 'desc': 'label: Hyperxanthinemia\ndefinition : An increased level of xanthine in the blood circulation.\nsynonyms :Increased circulating xanthine concentration\n'}


{'id': 'HP_0010934', 'url': 'http://purl.obolibrary.org/obo/HP_0010934', 'lbl': 'Xanthinuria', 'desc': 'label: Xanthinuria\ndefinition : An increased concentration of xanthine in the urine.\nsynonyms :Increased urinary xanthine\n'}


{'id': 'HP_0010935', 'url': 'http://purl.obolibrary.org/obo/HP_0010935', 'lbl': 'Abnormality of the upper urinary tract', 'desc': 'label: Abnormality of the upper urinary tract\ndefinition : An abnormality of the upper urinary tract.\nsynonyms :Abnormality of the upper urinary tract\n'}


{'id': 'HP_0010936', 'url': 'http://purl.obolibrary.org/obo/HP_0010936', 'lbl': 'Abnormality of the lower urinary tract', 'desc': 'label: Abnormality of the lower urinary tract\ndefinition : An abnormality of the lower urinary tract.\nsynonyms :\n'}


{'id': 'HP_0010937', 'url': 'http://purl.obolibrary.org/obo/HP_0010937', 'lbl': 'Abnormal nasal skeleton morphology', 'desc': 'label: Abnormal nasal skeleton morphology\ndefinition : An abnormality of the nasal skeleton.\nsynonyms :Abnormality of the nasal skeleton; Anomaly of the nasal skeleton; Deformity of the bones of the nose; Deformity of the nasal skeleton; Distortion of the bones of the nose; Distortion of the nasal skeleton; Malformation of the bones of the nose; Malformation of the nasal skeleton\n'}


{'id': 'HP_0010938', 'url': 'http://purl.obolibrary.org/obo/HP_0010938', 'lbl': 'Abnormal external nose morphology', 'desc': 'label: Abnormal external nose morphology\ndefinition : An abnormality of the external nose.\nsynonyms :Abnormality of the external nose; Anomaly of the external nose; Deformity of the external nose; Malformation of the external nose\n'}


{'id': 'HP_0010939', 'url': 'http://purl.obolibrary.org/obo/HP_0010939', 'lbl': 'Abnormal nasal bone morphology', 'desc': 'label: Abnormal nasal bone morphology\ndefinition : An abnormality of the nasal bone, comprising the left nasal bone and the right nasal bone.\nsynonyms :Abnormality of the nasal bone; Anomaly of the nasal bones; Deformity of the nasal bones; Malformation of the nasal bones\n'}


{'id': 'HP_0010940', 'url': 'http://purl.obolibrary.org/obo/HP_0010940', 'lbl': 'Aplasia/Hypoplasia of the nasal bone', 'desc': 'label: Aplasia/Hypoplasia of the nasal bone\ndefinition : Absence or underdevelopment of the nasal bone.\nsynonyms :\n'}


{'id': 'HP_0010941', 'url': 'http://purl.obolibrary.org/obo/HP_0010941', 'lbl': 'Aplasia of the nasal bone', 'desc': 'label: Aplasia of the nasal bone\ndefinition : Absence of the nasal bone.\nsynonyms :Failure of development of the nasal bone; Lack of development of the nasal bone; Absence of the nasal bone; Agenesis of the nasal bone; Missing nasal bone\n'}


{'id': 'HP_0010942', 'url': 'http://purl.obolibrary.org/obo/HP_0010942', 'lbl': 'Echogenic intracardiac focus', 'desc': 'label: Echogenic intracardiac focus\ndefinition : A finding of a focus of increased echogenicity upon prenatal ultrasound examination of the fetus. The foci may be present in one or both ventricles. Echogenic intracardiac focus (EICF) is defined as a focus of echogenicity comparable to bone, in the region of the papillary muscle in either or both ventricles of the fetal heart.\nsynonyms :\n'}


{'id': 'HP_0010943', 'url': 'http://purl.obolibrary.org/obo/HP_0010943', 'lbl': 'Echogenic fetal bowel', 'desc': 'label: Echogenic fetal bowel\ndefinition : Echogenic bowel is defined as fetal bowel with homogenous areas of echogenicity that are equal to or greater than that of surrounding bone.\nsynonyms :Echogenic bowel; Echogenic foetal bowel\n'}


{'id': 'HP_0010944', 'url': 'http://purl.obolibrary.org/obo/HP_0010944', 'lbl': 'Abnormal renal pelvis morphology', 'desc': 'label: Abnormal renal pelvis morphology\ndefinition : An abnormality of the renal pelvis.\nsynonyms :Abnormality of the renal pelvis\n'}


{'id': 'HP_0010945', 'url': 'http://purl.obolibrary.org/obo/HP_0010945', 'lbl': 'Fetal pyelectasis', 'desc': 'label: Fetal pyelectasis\ndefinition : Mild pyelectasis is defined as a hypoechoic spherical or elliptical space within the renal pelvis that measures at least 5mm and not more than 10 mm. The measurement is taken on a transverse section through the fetal renal pelvis using the maximum anterior-to-posterior measurement.\nsynonyms :Fetal renal pelvic dilatation; Foetal pyelectasis; Foetal renal pelvic dilatation; Mild fetal hydronephrosis; Mild foetal hydronephrosis\n'}


{'id': 'HP_0010946', 'url': 'http://purl.obolibrary.org/obo/HP_0010946', 'lbl': 'Dilatation of the renal pelvis', 'desc': 'label: Dilatation of the renal pelvis\ndefinition : The presence of dilatation of the renal pelvis.\nsynonyms :\n'}


{'id': 'HP_0010947', 'url': 'http://purl.obolibrary.org/obo/HP_0010947', 'lbl': 'Abnormality of ductus venosus blood flow', 'desc': 'label: Abnormality of ductus venosus blood flow\ndefinition : A first-trimester prenatal ultrasound finding of abnormal blood flow in the ductus venosus.\nsynonyms :\n'}


{'id': 'HP_0010948', 'url': 'http://purl.obolibrary.org/obo/HP_0010948', 'lbl': 'Abnormal fetal cardiovascular morphology', 'desc': 'label: Abnormal fetal cardiovascular morphology\ndefinition : A structural abnormality of the fetal circulation system. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes.\nsynonyms :Abnormality of the fetal cardiovascular system; Abnormality of the fetal circulation system; Abnormality of the foetal cardiovascular system; Abnormality of the foetal circulation system\n'}


{'id': 'HP_0010949', 'url': 'http://purl.obolibrary.org/obo/HP_0010949', 'lbl': 'Abnormality of umbilical vein blood flow', 'desc': 'label: Abnormality of umbilical vein blood flow\ndefinition : A first-trimester prenatal ultrasound finding of abnormal blood flow in the umbilical vein.\nsynonyms :\n'}


{'id': 'HP_0010950', 'url': 'http://purl.obolibrary.org/obo/HP_0010950', 'lbl': 'Abnormal fourth ventricle morphology', 'desc': 'label: Abnormal fourth ventricle morphology\ndefinition : An abnormality of the fourth ventricle.\nsynonyms :Abnormality of the fourth ventricle\n'}


{'id': 'HP_0010951', 'url': 'http://purl.obolibrary.org/obo/HP_0010951', 'lbl': 'Abnormal third ventricle morphology', 'desc': 'label: Abnormal third ventricle morphology\ndefinition : An abnormality of the third ventricle.\nsynonyms :Abnormality of the third ventricle\n'}


{'id': 'HP_0010952', 'url': 'http://purl.obolibrary.org/obo/HP_0010952', 'lbl': 'Mild fetal ventriculomegaly', 'desc': 'label: Mild fetal ventriculomegaly\ndefinition : A kind of ventriculomegaly occurring in the fetal period and usually diagnosed by prenatal ultrasound. Cerebral ventriculomegaly is defined by atrial measurements 10 mm or more. Mild ventriculomegaly (MVM) is defined as measurements between 10 and 15 mm. Measurements are obtained from an axial plane at the level of the thalamic nuclei just below the standard image to measure the BPD (PMID:16100637).\nsynonyms :Mild foetal ventriculomegaly\n'}


{'id': 'HP_0010953', 'url': 'http://purl.obolibrary.org/obo/HP_0010953', 'lbl': 'Noncommunicating hydrocephalus', 'desc': 'label: Noncommunicating hydrocephalus\ndefinition : A form of hydrocephalus in which the flow of cerebrospinal fluid (CSF) within the cerebral ventricular system or in the outlets of the CSF to the arachnoid space is obstructed.\nsynonyms :\n'}


{'id': 'HP_0010954', 'url': 'http://purl.obolibrary.org/obo/HP_0010954', 'lbl': 'Hypoplastic right heart', 'desc': 'label: Hypoplastic right heart\ndefinition : Underdevelopment of the right-sided structures of the heart.\nsynonyms :Hypoplastic right heart syndrome; Underdeveloped right heart\n'}


{'id': 'HP_0010955', 'url': 'http://purl.obolibrary.org/obo/HP_0010955', 'lbl': 'Dilatation of the bladder', 'desc': 'label: Dilatation of the bladder\ndefinition : The presence of a dilated urinary bladder.\nsynonyms :\n'}


{'id': 'HP_0010956', 'url': 'http://purl.obolibrary.org/obo/HP_0010956', 'lbl': 'Fetal megacystis', 'desc': 'label: Fetal megacystis\ndefinition : Fetal megacystis is an abnormally enlarged bladder identified at any gestational age.\nsynonyms :Foetal megacystis\n'}


{'id': 'HP_0010957', 'url': 'http://purl.obolibrary.org/obo/HP_0010957', 'lbl': 'Congenital posterior urethral valve', 'desc': 'label: Congenital posterior urethral valve\ndefinition : A developmental defect resulting in an obstructing membrane in the posterior male urethra.\nsynonyms :Posterior urethral valve; Posterior urethral valves\n'}


{'id': 'HP_0010958', 'url': 'http://purl.obolibrary.org/obo/HP_0010958', 'lbl': 'Bilateral renal agenesis', 'desc': 'label: Bilateral renal agenesis\ndefinition : A bilateral form of agenesis of the kidney.\nsynonyms :\n'}


{'id': 'HP_0010959', 'url': 'http://purl.obolibrary.org/obo/HP_0010959', 'lbl': 'Congenital pulmonary airway malformation', 'desc': 'label: Congenital pulmonary airway malformation\ndefinition : Congenital pulmonary airway malformation (CPAM) - previously known as congenital cystic adenomatoid malformation (CCAM) - is a relatively rare developmental malformation of the lower respiratory tract. It is a hamartomatous, dysplastic developmental abnormality of the lung characterized by abnormal airway patterning during lung branching morphogenesis and is formed by abnormal branching of the immature bronchioles.\nsynonyms :CCAM; Congenital cystic adenomatoid malformation of the lung; Congenital cystic disease of the lung; Cystic adenomatoid lung disease\n'}


{'id': 'HP_0010960', 'url': 'http://purl.obolibrary.org/obo/HP_0010960', 'lbl': 'Bronchopulmonary sequestration', 'desc': 'label: Bronchopulmonary sequestration\ndefinition : The presence of microscopic cystic masses of nonfunctioning pulmonary tissue that lack an obvious communication with the tracheobronchial tree.\nsynonyms :\n'}


{'id': 'HP_0010961', 'url': 'http://purl.obolibrary.org/obo/HP_0010961', 'lbl': 'Intralobar sequestration', 'desc': 'label: Intralobar sequestration\ndefinition : A kind of bronchopulmonary sequestration that is incorporated into the normal surrounding lung.\nsynonyms :\n'}


{'id': 'HP_0010962', 'url': 'http://purl.obolibrary.org/obo/HP_0010962', 'lbl': 'Extralobar sequestration', 'desc': 'label: Extralobar sequestration\ndefinition : A kind of bronchopulmonary sequestration that is completely discrete from the normal lung and is surrounded by separate pleura.\nsynonyms :\n'}


{'id': 'HP_0010963', 'url': 'http://purl.obolibrary.org/obo/HP_0010963', 'lbl': 'Absence of stomach bubble on fetal sonography', 'desc': "label: Absence of stomach bubble on fetal sonography\ndefinition : By the 14th week of gestation it is nearly always possible to visualized the fluid-filled fetal stomach bubble on prenatal sonography. This term refers to the absence of a normal fetal stomach bubble on fetal ultrasonography performed at around 16 to 20 weeks' gestation.\nsynonyms :Absence of stomach bubble on foetal sonography; Absent stomach bubble; Non-visualisation of the fetal stomach\n"}


{'id': 'HP_0010964', 'url': 'http://purl.obolibrary.org/obo/HP_0010964', 'lbl': 'Abnormal circulating long-chain fatty-acid concentration', 'desc': 'label: Abnormal circulating long-chain fatty-acid concentration\ndefinition : Any deviation from the normal concentration of a long-chain fatty acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010965', 'url': 'http://purl.obolibrary.org/obo/HP_0010965', 'lbl': 'Abnormal circulating phytanic acid concentration', 'desc': 'label: Abnormal circulating phytanic acid concentration\ndefinition : Any deviation from the normal concentration of phytanic acid in the blood circulation.\nsynonyms :Abnormal circulating phytanic acid level\n'}


{'id': 'HP_0010966', 'url': 'http://purl.obolibrary.org/obo/HP_0010966', 'lbl': 'Abnormal circulating fatty-acid anion concentration', 'desc': 'label: Abnormal circulating fatty-acid anion concentration\ndefinition : Any deviation from the normal concentration of a fatty acid anion in the blood circulation.\nsynonyms :Abnormality of fatty acid anion\n'}


{'id': 'HP_0010967', 'url': 'http://purl.obolibrary.org/obo/HP_0010967', 'lbl': 'Abnormal circulating carnitine concentration', 'desc': 'label: Abnormal circulating carnitine concentration\ndefinition : Any deviation from the normal concentration of carnitine in the blood circulation.\nsynonyms :Carnitine levels abnormal\n'}


{'id': 'HP_0010968', 'url': 'http://purl.obolibrary.org/obo/HP_0010968', 'lbl': 'Abnormality of liposaccharide metabolism', 'desc': 'label: Abnormality of liposaccharide metabolism\ndefinition : An abnormality of liposaccharide metabolism.\nsynonyms :\n'}


{'id': 'HP_0010969', 'url': 'http://purl.obolibrary.org/obo/HP_0010969', 'lbl': 'Abnormality of glycolipid metabolism', 'desc': 'label: Abnormality of glycolipid metabolism\ndefinition : An abnormality of glycolipid metabolism.\nsynonyms :\n'}


{'id': 'HP_0010970', 'url': 'http://purl.obolibrary.org/obo/HP_0010970', 'lbl': 'Blood group antigen abnormality', 'desc': 'label: Blood group antigen abnormality\ndefinition : An abnormality of an erythrocyte cell surface molecule.\nsynonyms :\n'}


{'id': 'HP_0010971', 'url': 'http://purl.obolibrary.org/obo/HP_0010971', 'lbl': 'Absence of Lutheran antigen on erythrocytes', 'desc': 'label: Absence of Lutheran antigen on erythrocytes\ndefinition : Absence of the Lutheran antigen (a type I integral membrane glycoprotein) from the surface of red blood cells.\nsynonyms :\n'}


{'id': 'HP_0010972', 'url': 'http://purl.obolibrary.org/obo/HP_0010972', 'lbl': 'Anemia of inadequate production', 'desc': 'label: Anemia of inadequate production\ndefinition : A kind of anemia characterized by inadequate production of erythrocytes.\nsynonyms :Anaemia of inadequate production; Anemia, dyserythropoietic; Defective erythropoiesis; Dyserythropoietic anaemia; Dyserythropoietic anemia; Ineffective erythropoiesis\n'}


{'id': 'HP_0010974', 'url': 'http://purl.obolibrary.org/obo/HP_0010974', 'lbl': 'Abnormal myeloid leukocyte morphology', 'desc': 'label: Abnormal myeloid leukocyte morphology\ndefinition : An abnormality of myeloid leukocytes.\nsynonyms :Abnormality of myeloid leukocytes\n'}


{'id': 'HP_0010975', 'url': 'http://purl.obolibrary.org/obo/HP_0010975', 'lbl': 'Abnormal B cell count', 'desc': 'label: Abnormal B cell count\ndefinition : A deviation from the normal count of B cells, i.e., the cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells.\nsynonyms :Abnormal number of B cells; Abnormal numbers of B cells; Abnormality of B cell count; Abnormality of B cell numbers\n'}


{'id': 'HP_0010976', 'url': 'http://purl.obolibrary.org/obo/HP_0010976', 'lbl': 'B lymphocytopenia', 'desc': 'label: B lymphocytopenia\ndefinition : An abnormal decrease from the normal count of B cells.\nsynonyms :B cell deficiency; B cell lymphopenia; Decreased B cell count; Low B cell count; Reduction in B cell number\n'}


{'id': 'HP_0010977', 'url': 'http://purl.obolibrary.org/obo/HP_0010977', 'lbl': 'Abnormal phagocytosis', 'desc': 'label: Abnormal phagocytosis\ndefinition : An abnormal functioning of phagocytosis. Phagocytosis is an elegant but complex process for the ingestion and elimination of pathogens, but it is also important for the elimination of apoptotic cells and hence fundamental for tissue homeostasis. Phagocytosis can be divided into four main steps: (i) recognition of the target particle, (ii) signaling to activate the internalization machinery, (iii) phagosome formation, and (iv) phagolysosome maturation.\nsynonyms :\n'}


{'id': 'HP_0010978', 'url': 'http://purl.obolibrary.org/obo/HP_0010978', 'lbl': 'Abnormality of immune system physiology', 'desc': 'label: Abnormality of immune system physiology\ndefinition : A functional abnormality of the immune system.\nsynonyms :\n'}


{'id': 'HP_0010979', 'url': 'http://purl.obolibrary.org/obo/HP_0010979', 'lbl': 'Abnormality of lipoprotein cholesterol concentration', 'desc': 'label: Abnormality of lipoprotein cholesterol concentration\ndefinition : An abnormal increase or decrease in the level of lipoprotein cholesterol in the blood.\nsynonyms :Abnormality of the level of lipoprotein cholesterol\n'}


{'id': 'HP_0010980', 'url': 'http://purl.obolibrary.org/obo/HP_0010980', 'lbl': 'Hyperlipoproteinemia', 'desc': 'label: Hyperlipoproteinemia\ndefinition : An abnormal increase in the level of lipoprotein cholesterol in the blood.\nsynonyms :\n'}


{'id': 'HP_0010981', 'url': 'http://purl.obolibrary.org/obo/HP_0010981', 'lbl': 'Hypolipoproteinemia', 'desc': 'label: Hypolipoproteinemia\ndefinition : An abnormal decrease in the level of lipoprotein cholesterol in the blood.\nsynonyms :Lack of fat in blood\n'}


{'id': 'HP_0010982', 'url': 'http://purl.obolibrary.org/obo/HP_0010982', 'lbl': 'Polygenic inheritance', 'desc': 'label: Polygenic inheritance\ndefinition : A type of multifactorial inheritance governed by the simultaneous action of many (more than three) gene loci.\nsynonyms :\n'}


{'id': 'HP_0010983', 'url': 'http://purl.obolibrary.org/obo/HP_0010983', 'lbl': 'Oligogenic inheritance', 'desc': 'label: Oligogenic inheritance\ndefinition : A type of multifactorial inheritance governed by the simultaneous action of a few gene loci. It is recommended this term be used for traits governed by three loci, although it is noted that usage of this term in the literature is not uniform.\nsynonyms :\n'}


{'id': 'HP_0010984', 'url': 'http://purl.obolibrary.org/obo/HP_0010984', 'lbl': 'Digenic inheritance', 'desc': 'label: Digenic inheritance\ndefinition : A type of multifactorial inheritance governed by the simultaneous action of two gene loci.\nsynonyms :\n'}


{'id': 'HP_0010985', 'url': 'http://purl.obolibrary.org/obo/HP_0010985', 'lbl': 'obsolete Gonosomal inheritance', 'desc': 'label: obsolete Gonosomal inheritance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0010987', 'url': 'http://purl.obolibrary.org/obo/HP_0010987', 'lbl': 'Abnormal cellular immune system morphology', 'desc': 'label: Abnormal cellular immune system morphology\ndefinition : An abnormality of the morphology or counts of the cells that make up the immune system.\nsynonyms :\n'}


{'id': 'HP_0010988', 'url': 'http://purl.obolibrary.org/obo/HP_0010988', 'lbl': 'Abnormality of the extrinsic pathway', 'desc': 'label: Abnormality of the extrinsic pathway\ndefinition : An abnormality of the extrinsic pathway (also known as the tissue factor pathway) of the coagulation cascade.\nsynonyms :\n'}


{'id': 'HP_0010989', 'url': 'http://purl.obolibrary.org/obo/HP_0010989', 'lbl': 'Abnormality of the intrinsic pathway', 'desc': 'label: Abnormality of the intrinsic pathway\ndefinition : An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade.\nsynonyms :\n'}


{'id': 'HP_0010990', 'url': 'http://purl.obolibrary.org/obo/HP_0010990', 'lbl': 'Abnormality of the common coagulation pathway', 'desc': 'label: Abnormality of the common coagulation pathway\ndefinition : An abnormality of blood coagulation, common pathway.\nsynonyms :\n'}


{'id': 'HP_0010991', 'url': 'http://purl.obolibrary.org/obo/HP_0010991', 'lbl': 'Abnormal morphology of the abdominal musculature', 'desc': 'label: Abnormal morphology of the abdominal musculature\ndefinition : An abnormality of the abdominal musculature.\nsynonyms :Abnormality of the abdominal musculature\n'}


{'id': 'HP_0010992', 'url': 'http://purl.obolibrary.org/obo/HP_0010992', 'lbl': 'Stress urinary incontinence', 'desc': 'label: Stress urinary incontinence\ndefinition : Involuntary urine leakage synchronous with exertion, or actions such as sneezing, or coughing.\nsynonyms :\n'}


{'id': 'HP_0010993', 'url': 'http://purl.obolibrary.org/obo/HP_0010993', 'lbl': 'Abnormal cerebral subcortex morphology', 'desc': 'label: Abnormal cerebral subcortex morphology\ndefinition : An abnormality of the cerebral subcortex.\nsynonyms :Abnormality of the cerebral medulla; Abnormality of the cerebral subcortex\n'}


{'id': 'HP_0010994', 'url': 'http://purl.obolibrary.org/obo/HP_0010994', 'lbl': 'Abnormal corpus striatum morphology', 'desc': 'label: Abnormal corpus striatum morphology\ndefinition : Abnormality of the striatum, which is the largest nucleus of the basal ganglia, comprising the caudate, putamen and ventral striatum, including the nucleus accumbens.\nsynonyms :Abnormality of the neostriatum; Abnormality of the striate nucleus; Abnormality of the striatum\n'}


{'id': 'HP_0010995', 'url': 'http://purl.obolibrary.org/obo/HP_0010995', 'lbl': 'Abnormal circulating dicarboxylic acid concentration', 'desc': 'label: Abnormal circulating dicarboxylic acid concentration\ndefinition : Any deviation from the normal concentration of a dicarboxylic acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010996', 'url': 'http://purl.obolibrary.org/obo/HP_0010996', 'lbl': 'Abnormal circulating monocarboxylic acid concentration', 'desc': 'label: Abnormal circulating monocarboxylic acid concentration\ndefinition : Any deviation from the normal concentration of a monocarboxylic acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0010997', 'url': 'http://purl.obolibrary.org/obo/HP_0010997', 'lbl': 'Chromosomal breakage induced by ionizing radiation', 'desc': 'label: Chromosomal breakage induced by ionizing radiation\ndefinition : Increased amount of chromosomal breaks in cultured blood lymphocytes or other cells induced by treatment with ionizing radiation.\nsynonyms :Chromosomal breakage induced by ionising radiation; Increased cellular radiosensitivity; Radiation-induced chromosome instability\n'}


{'id': 'HP_0010998', 'url': 'http://purl.obolibrary.org/obo/HP_0010998', 'lbl': 'Increased susceptibility to spontaneous sister chromatid exchange', 'desc': 'label: Increased susceptibility to spontaneous sister chromatid exchange\ndefinition : An increase in the number of spontaneous sister chromatid exchanges observed in cell culture of lymphocytes or other cells.\nsynonyms :\n'}


{'id': 'HP_0010999', 'url': 'http://purl.obolibrary.org/obo/HP_0010999', 'lbl': 'Aplasia of the optic tract', 'desc': 'label: Aplasia of the optic tract\ndefinition : \nsynonyms :Absent optic tract\n'}


{'id': 'HP_0011000', 'url': 'http://purl.obolibrary.org/obo/HP_0011000', 'lbl': 'Aplasia/Hypoplasia of the optic tract', 'desc': 'label: Aplasia/Hypoplasia of the optic tract\ndefinition : \nsynonyms :Absent/small optic tract; Absent/underdeveloped optic tract\n'}


{'id': 'HP_0011001', 'url': 'http://purl.obolibrary.org/obo/HP_0011001', 'lbl': 'Increased bone mineral density', 'desc': 'label: Increased bone mineral density\ndefinition : An abnormal increase of bone mineral density, that is, of the amount of matter per cubic centimeter of bones which is often referred to as osteosclerosis. Osteosclerosis can be detected on radiological examination as an increased whiteness (density) of affected bones.\nsynonyms :Increased bone density; Increased bone mineral density; Osteosclerosis; Osteosclerosis of bones\n'}


{'id': 'HP_0011002', 'url': 'http://purl.obolibrary.org/obo/HP_0011002', 'lbl': 'Osteopetrosis', 'desc': 'label: Osteopetrosis\ndefinition : Abnormally increased formation of dense trabecular bone tissue. Despite the increased density of bone tissue, osteopetrotic bones tend to be more fracture-prone than normal.\nsynonyms :Harder, denser, fracture-prone bones; Albers-Schoenberg disease; Albers-Schonberg disease; Albers-Schönberg disease; Marble bone disease\n'}


{'id': 'HP_0011003', 'url': 'http://purl.obolibrary.org/obo/HP_0011003', 'lbl': 'High myopia', 'desc': 'label: High myopia\ndefinition : A severe form of myopia with greater than -6.00 diopters.\nsynonyms :Severe myopia; Severe myopia (> -6.00 diopters); Severe near sightedness; Severely close sighted; Severely near sighted\n'}


{'id': 'HP_0011004', 'url': 'http://purl.obolibrary.org/obo/HP_0011004', 'lbl': 'Abnormal systemic arterial morphology', 'desc': 'label: Abnormal systemic arterial morphology\ndefinition : An abnormality of the systemic arterial tree, which consists of the aorta and other systemic arteries.\nsynonyms :Abnormal systemic artery morphology; Abnormality of the systemic arterial tree; Systemic artery abnormality; Arterial abnormalities\n'}


{'id': 'HP_0011005', 'url': 'http://purl.obolibrary.org/obo/HP_0011005', 'lbl': 'Mixed cirrhosis', 'desc': 'label: Mixed cirrhosis\ndefinition : A type of cirrhosis characterized by the presence of regenerative nodules of a variety of sizes.\nsynonyms :\n'}


{'id': 'HP_0011006', 'url': 'http://purl.obolibrary.org/obo/HP_0011006', 'lbl': 'Abnormal morphology of the musculature of the neck', 'desc': 'label: Abnormal morphology of the musculature of the neck\ndefinition : An abnormality of the neck musculature.\nsynonyms :Abnormality of cervical musculature; Abnormality of the musculature of the neck; Neck muscle issue\n'}


{'id': 'HP_0011008', 'url': 'http://purl.obolibrary.org/obo/HP_0011008', 'lbl': 'Temporal pattern', 'desc': 'label: Temporal pattern\ndefinition : The speed at which disease manifestations appear and develop.\nsynonyms :Speed of onset\n'}


{'id': 'HP_0011009', 'url': 'http://purl.obolibrary.org/obo/HP_0011009', 'lbl': 'Acute', 'desc': 'label: Acute\ndefinition : Sudden appearance of disease manifestations over a short period of time.\nsynonyms :Acute onset\n'}


{'id': 'HP_0011010', 'url': 'http://purl.obolibrary.org/obo/HP_0011010', 'lbl': 'Chronic', 'desc': 'label: Chronic\ndefinition : Slow, creeping onset, slow progress and long continuance of disease manifestations.\nsynonyms :Chronic\n'}


{'id': 'HP_0011011', 'url': 'http://purl.obolibrary.org/obo/HP_0011011', 'lbl': 'Subacute', 'desc': 'label: Subacute\ndefinition : Somewhat rapid onset and change of disease manifestations.\nsynonyms :\n'}


{'id': 'HP_0011012', 'url': 'http://purl.obolibrary.org/obo/HP_0011012', 'lbl': 'Abnormal circulating polysaccharide concentration', 'desc': 'label: Abnormal circulating polysaccharide concentration\ndefinition : A deviation from the normal concentration of a polysaccharide in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0011013', 'url': 'http://purl.obolibrary.org/obo/HP_0011013', 'lbl': 'Abnormal circulating carbohydrate concentration', 'desc': 'label: Abnormal circulating carbohydrate concentration\ndefinition : A deviation from the normal concentration of a carbohydrate in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0011014', 'url': 'http://purl.obolibrary.org/obo/HP_0011014', 'lbl': 'Abnormal glucose homeostasis', 'desc': 'label: Abnormal glucose homeostasis\ndefinition : Abnormality of glucose homeostasis.\nsynonyms :\n'}


{'id': 'HP_0011015', 'url': 'http://purl.obolibrary.org/obo/HP_0011015', 'lbl': 'Abnormal blood glucose concentration', 'desc': 'label: Abnormal blood glucose concentration\ndefinition : An abnormality of the concentration of glucose in the blood.\nsynonyms :Abnormality of blood glucose concentration\n'}


{'id': 'HP_0011016', 'url': 'http://purl.obolibrary.org/obo/HP_0011016', 'lbl': 'obsolete Abnormality of urine glucose concentration', 'desc': 'label: obsolete Abnormality of urine glucose concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011017', 'url': 'http://purl.obolibrary.org/obo/HP_0011017', 'lbl': 'Abnormal cellular physiology', 'desc': 'label: Abnormal cellular physiology\ndefinition : An abnormality in a cellular process.\nsynonyms :Abnormality of cell physiology\n'}


{'id': 'HP_0011018', 'url': 'http://purl.obolibrary.org/obo/HP_0011018', 'lbl': 'Abnormality of the cell cycle', 'desc': 'label: Abnormality of the cell cycle\ndefinition : An abnormality of the cell cycle.\nsynonyms :Abnormality of the cell cycle\n'}


{'id': 'HP_0011019', 'url': 'http://purl.obolibrary.org/obo/HP_0011019', 'lbl': 'Abnormality of chromosome condensation', 'desc': 'label: Abnormality of chromosome condensation\ndefinition : An abnormality of chromosome condensation.\nsynonyms :\n'}


{'id': 'HP_0011020', 'url': 'http://purl.obolibrary.org/obo/HP_0011020', 'lbl': 'Abnormality of mucopolysaccharide metabolism', 'desc': 'label: Abnormality of mucopolysaccharide metabolism\ndefinition : An abnormality of the metabolism of mucopolysaccharide.\nsynonyms :\n'}


{'id': 'HP_0011021', 'url': 'http://purl.obolibrary.org/obo/HP_0011021', 'lbl': 'Abnormality of circulating enzyme level', 'desc': 'label: Abnormality of circulating enzyme level\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011022', 'url': 'http://purl.obolibrary.org/obo/HP_0011022', 'lbl': 'Abnormal circulating unsaturated fatty acid concentration', 'desc': 'label: Abnormal circulating unsaturated fatty acid concentration\ndefinition : A deviation from the normal concentration of an unsaturated fatty acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0011023', 'url': 'http://purl.obolibrary.org/obo/HP_0011023', 'lbl': 'Abnormal circulating prostaglandin circulation', 'desc': 'label: Abnormal circulating prostaglandin circulation\ndefinition : Any deviation from the normal concentration of a prostaglandin in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0011024', 'url': 'http://purl.obolibrary.org/obo/HP_0011024', 'lbl': 'Abnormality of the gastrointestinal tract', 'desc': 'label: Abnormality of the gastrointestinal tract\ndefinition : An abnormality of the gastrointestinal tract.\nsynonyms :Abnormality of the GI tract; Abnormality of the gastrointestinal tract; Digestive system disease; Gastrointestinal disease\n'}


{'id': 'HP_0011025', 'url': 'http://purl.obolibrary.org/obo/HP_0011025', 'lbl': 'Abnormal cardiovascular system physiology', 'desc': 'label: Abnormal cardiovascular system physiology\ndefinition : Abnormal functionality of the cardiovascular system.\nsynonyms :Abnormality of cardiovascular system physiology\n'}


{'id': 'HP_0011026', 'url': 'http://purl.obolibrary.org/obo/HP_0011026', 'lbl': 'Aplasia/Hypoplasia of the vagina', 'desc': 'label: Aplasia/Hypoplasia of the vagina\ndefinition : Aplasia or developmental hypoplasia of the vagina.\nsynonyms :Absent/small vagina; Absent/underdeveloped vagina\n'}


{'id': 'HP_0011027', 'url': 'http://purl.obolibrary.org/obo/HP_0011027', 'lbl': 'Abnormal fallopian tube morphology', 'desc': 'label: Abnormal fallopian tube morphology\ndefinition : An abnormality of the fallopian tube.\nsynonyms :Abnormality of the fallopian tube\n'}


{'id': 'HP_0011028', 'url': 'http://purl.obolibrary.org/obo/HP_0011028', 'lbl': 'Abnormality of blood circulation', 'desc': 'label: Abnormality of blood circulation\ndefinition : An abnormality of blood circulation.\nsynonyms :Blood circulation disorder\n'}


{'id': 'HP_0011029', 'url': 'http://purl.obolibrary.org/obo/HP_0011029', 'lbl': 'Internal hemorrhage', 'desc': 'label: Internal hemorrhage\ndefinition : The presence of hemorrhage within the body.\nsynonyms :Internal bleeding; Internal haemorrhage\n'}


{'id': 'HP_0011030', 'url': 'http://purl.obolibrary.org/obo/HP_0011030', 'lbl': 'Abnormal blood transition element cation concentration', 'desc': 'label: Abnormal blood transition element cation concentration\ndefinition : An abnormality of the homeostasis (concentration) of transition element cation.\nsynonyms :Abnormality of transition element cation homeostasis\n'}


{'id': 'HP_0011031', 'url': 'http://purl.obolibrary.org/obo/HP_0011031', 'lbl': 'Abnormality of iron homeostasis', 'desc': 'label: Abnormality of iron homeostasis\ndefinition : An abnormality of the homeostasis (concentration) of iron cation.\nsynonyms :\n'}


{'id': 'HP_0011032', 'url': 'http://purl.obolibrary.org/obo/HP_0011032', 'lbl': 'Abnormality of fluid regulation', 'desc': 'label: Abnormality of fluid regulation\ndefinition : An abnormality of the regulation of body fluids.\nsynonyms :Abnormality of fluid regulation; Fluid imbalance\n'}


{'id': 'HP_0011033', 'url': 'http://purl.obolibrary.org/obo/HP_0011033', 'lbl': 'Impairment of fructose metabolism', 'desc': 'label: Impairment of fructose metabolism\ndefinition : An impairment of a fructose metabolic process.\nsynonyms :\n'}


{'id': 'HP_0011034', 'url': 'http://purl.obolibrary.org/obo/HP_0011034', 'lbl': 'Amyloidosis', 'desc': 'label: Amyloidosis\ndefinition : The presence of amyloid deposition in one or more tissues. Amyloidosis may be defined as the extracellular deposition of amyloid in one or more sites of the body.\nsynonyms :Amyloid disease\n'}


{'id': 'HP_0011035', 'url': 'http://purl.obolibrary.org/obo/HP_0011035', 'lbl': 'Abnormal renal cortex morphology', 'desc': 'label: Abnormal renal cortex morphology\ndefinition : An abnormality of the cortex of the kidney.\nsynonyms :Abnormality of renal cortex morphology\n'}


{'id': 'HP_0011036', 'url': 'http://purl.obolibrary.org/obo/HP_0011036', 'lbl': 'Abnormality of renal excretion', 'desc': 'label: Abnormality of renal excretion\ndefinition : An altered ability of the kidneys to void urine and/or specific substances.\nsynonyms :\n'}


{'id': 'HP_0011037', 'url': 'http://purl.obolibrary.org/obo/HP_0011037', 'lbl': 'Decreased urine output', 'desc': 'label: Decreased urine output\ndefinition : A decreased rate of urine production.\nsynonyms :\n'}


{'id': 'HP_0011038', 'url': 'http://purl.obolibrary.org/obo/HP_0011038', 'lbl': 'Abnormal renal tubular resorption', 'desc': 'label: Abnormal renal tubular resorption\ndefinition : An abnormality of renal absorption.\nsynonyms :Abnormal renal resorption; Abnormality of renal resorption\n'}


{'id': 'HP_0011039', 'url': 'http://purl.obolibrary.org/obo/HP_0011039', 'lbl': 'Abnormal helix morphology', 'desc': 'label: Abnormal helix morphology\ndefinition : An abnormality of the helix. The helix is the outer rim of the ear that extends from the insertion of the ear on the scalp (root) to the termination of the cartilage at the earlobe.\nsynonyms :Abnormal helices; Abnormality of the helix; Helix abnormal\n'}


{'id': 'HP_0011040', 'url': 'http://purl.obolibrary.org/obo/HP_0011040', 'lbl': 'Abnormal intrahepatic bile duct morphology', 'desc': 'label: Abnormal intrahepatic bile duct morphology\ndefinition : An abnormality of the intrahepatic bile duct.\nsynonyms :Abnormality of the intrahepatic bile duct\n'}


{'id': 'HP_0011041', 'url': 'http://purl.obolibrary.org/obo/HP_0011041', 'lbl': 'Aplasia/Hypoplasia of the cervical spine', 'desc': 'label: Aplasia/Hypoplasia of the cervical spine\ndefinition : Aplasia or developmental hypoplasia of the cervical vertebral column.\nsynonyms :Absent/small cervical spine; Absent/underdeveloped cervical spine\n'}


{'id': 'HP_0011042', 'url': 'http://purl.obolibrary.org/obo/HP_0011042', 'lbl': 'Abnormal blood potassium concentration', 'desc': 'label: Abnormal blood potassium concentration\ndefinition : An abnormal concentration of potassium.\nsynonyms :Abnormal blood K concentration; Abnormality of potassium homeostasis\n'}


{'id': 'HP_0011043', 'url': 'http://purl.obolibrary.org/obo/HP_0011043', 'lbl': 'Abnormal circulating adrenocorticotropin concentration', 'desc': 'label: Abnormal circulating adrenocorticotropin concentration\ndefinition : An abnormal concentration of corticotropin in the blood.\nsynonyms :Abnormality of circulating corticotropin level; Abnormality of circulating ACTH level; Abnormality of circulating adrenocorticotropic hormone level; Abnormality of circulating adrenocorticotropin level\n'}


{'id': 'HP_0011044', 'url': 'http://purl.obolibrary.org/obo/HP_0011044', 'lbl': 'Abnormal number of permanent teeth', 'desc': 'label: Abnormal number of permanent teeth\ndefinition : The presence of an altered number of of permanent teeth.\nsynonyms :Abnormal complement of permanent teeth; Abnormal number of adult teeth; Abnormal number of permanent teeth; Abnormal number of secondary dentition; Abnormal permanent tooth count\n'}


{'id': 'HP_0011045', 'url': 'http://purl.obolibrary.org/obo/HP_0011045', 'lbl': 'Agenesis of permanent maxillary central incisor', 'desc': 'label: Agenesis of permanent maxillary central incisor\ndefinition : Agenesis of upper secondary incisor.\nsynonyms :Agenesis of adult maxillary central incisor; Failure of development of permanent maxillary central incisor; Absence of permanent maxillary central incisor; Absence of permanent upper central incisor; Absence of permanent upper front tooth; Missing adult upper central incisor; Missing permanent maxillary central incisor; Missing permanent upper central incisor; Missing permanent upper front tooth\n'}


{'id': 'HP_0011046', 'url': 'http://purl.obolibrary.org/obo/HP_0011046', 'lbl': 'Agenesis of primary maxillary central incisor', 'desc': 'label: Agenesis of primary maxillary central incisor\ndefinition : Agenesis of upper central primary incisor.\nsynonyms :Agenesis of deciduous maxillary central incisor; Failure of development of deciduous maxillary central incisor; Failure of development of primary maxillary central incisor; Absence of deciduous maxillary central incisor; Absence of primary maxillary central incisor; Absence of upper front baby tooth; Missing deciduous maxillary central incisor; Missing primary maxillary central incisor; Missing upper front baby tooth; Missing upper front milk tooth\n'}


{'id': 'HP_0011047', 'url': 'http://purl.obolibrary.org/obo/HP_0011047', 'lbl': 'Agenesis of primary mandibular central incisor', 'desc': 'label: Agenesis of primary mandibular central incisor\ndefinition : Agenesis of lower primary incisor.\nsynonyms :Agenesis of deciduous lower central incisor; Agenesis of primary lower central incisor; Failure of development of deciduous mandibular central incisor; Failure of development of primary mandibular central incisor; Absence of deciduous mandibular central incisor; Absence of primary mandibular central incisor; Missing deciduous mandibular central incisor; Missing lower central incisor milk tooth; Missing lower front baby tooth; Missing lower front milk tooth; Missing lower front primary tooth; Missing primary mandibular central incisor\n'}


{'id': 'HP_0011048', 'url': 'http://purl.obolibrary.org/obo/HP_0011048', 'lbl': 'Agenesis of permanent mandibular central incisor', 'desc': 'label: Agenesis of permanent mandibular central incisor\ndefinition : Agenesis of lower secondary incisor.\nsynonyms :Agenesis of adult mandibular central incisor; Failure of development of permanent mandibular central incisor; Absence of permanent lower central incisor; Absence of permanent lower front tooth; Absence of permanent mandibular central incisor; Missing adult lower central incisor; Missing permanent lower central incisor; Missing permanent lower front tooth; Missing permanent mandibular central incisor\n'}


{'id': 'HP_0011049', 'url': 'http://purl.obolibrary.org/obo/HP_0011049', 'lbl': 'Agenesis of primary maxillary lateral incisor', 'desc': 'label: Agenesis of primary maxillary lateral incisor\ndefinition : Agenesis of one or more maxillary lateral incisor, comprising the maxillary lateral primary incisor.\nsynonyms :Agenesis of deciduous maxillary lateral incisor; Failure of development of deciduous maxillary lateral incisor; Failure of development of primary maxillary lateral incisor; Absence of deciduous maxillary lateral incisor; Absence of primary maxillary lateral incisor; Missing deciduous maxillary lateral incisor; Missing primary maxillary lateral incisor\n'}


{'id': 'HP_0011050', 'url': 'http://purl.obolibrary.org/obo/HP_0011050', 'lbl': 'Agenesis of permanent maxillary lateral incisor', 'desc': 'label: Agenesis of permanent maxillary lateral incisor\ndefinition : Agenesis of one or more upper lateral secondary incisor.\nsynonyms :Agenesis of permanent upper lateral incisor; Failure of development of permanent maxillary lateral incisor; Failure of development of permanent upper lateral incisor; Absence of permanent maxillary lateral incisor; Missing permanent maxillary lateral incisor; Missing permanent upper lateral incisor\n'}


{'id': 'HP_0011051', 'url': 'http://purl.obolibrary.org/obo/HP_0011051', 'lbl': 'Agenesis of premolar', 'desc': 'label: Agenesis of premolar\ndefinition : Agenesis of premolar tooth.\nsynonyms :Agenesis of bicuspid; Failure of development of bicuspid; Failure of development of premolar; Absence of bicuspid; Absence of premolar; Missing bicuspid; Missing premolar\n'}


{'id': 'HP_0011052', 'url': 'http://purl.obolibrary.org/obo/HP_0011052', 'lbl': 'Agenesis of maxillary premolar', 'desc': 'label: Agenesis of maxillary premolar\ndefinition : Agenesis of maxillary premolar.\nsynonyms :Agenesis of maxillary bicuspid; Failure of development of maxillary bicuspid; Failure of development of maxillary premolar; Absence of maxillary bicuspid; Absence of maxillary premolar; Absence of upper premolar; Missing maxillary premolar; Missing upper bicuspid; Missing upper premolar\n'}


{'id': 'HP_0011053', 'url': 'http://purl.obolibrary.org/obo/HP_0011053', 'lbl': 'Agenesis of mandibular premolar', 'desc': 'label: Agenesis of mandibular premolar\ndefinition : Agenesis of mandibular premolar.\nsynonyms :Failure of development of mandibular premolar; Absence of lower premolar; Absence of mandibular premolar; Missing lower premolar; Missing mandibular premolar\n'}


{'id': 'HP_0011054', 'url': 'http://purl.obolibrary.org/obo/HP_0011054', 'lbl': 'Agenesis of molar', 'desc': 'label: Agenesis of molar\ndefinition : Agenesis of molar tooth.\nsynonyms :Absent molars; Failure of development of molar; Absence of molar; Missing molar\n'}


{'id': 'HP_0011055', 'url': 'http://purl.obolibrary.org/obo/HP_0011055', 'lbl': 'Agenesis of permanent molar', 'desc': 'label: Agenesis of permanent molar\ndefinition : Agenesis of secondary molar tooth.\nsynonyms :Agenesis of secondary molar; Failure of development of permanent molar; Failure of development of secondary molar; Absence of adult molar; Absence of permanent molar; Missing adult molar; Missing permanent molar\n'}


{'id': 'HP_0011056', 'url': 'http://purl.obolibrary.org/obo/HP_0011056', 'lbl': 'Agenesis of first permanent molar tooth', 'desc': 'label: Agenesis of first permanent molar tooth\ndefinition : Agenesis of either maxillary first permanent molar or mandibular first permanent molar or both.\nsynonyms :Agenesis of six year molar; Failure of development of first permanent molar; Failure of development of six year molar; Absence of first permanent molar; Absence of six year molar; Missing first permanent molar; Missing six year molar\n'}


{'id': 'HP_0011057', 'url': 'http://purl.obolibrary.org/obo/HP_0011057', 'lbl': 'Agenesis of second permanent molar', 'desc': 'label: Agenesis of second permanent molar\ndefinition : Agenesis of either mandibular second permanent molar or maxillary second permanent molar.\nsynonyms :Agenesis of twelve year molar; Failure of development of second permanent molar; Failure of development of twelve year molar; Absence of second permanent molar; Absence of twelve year molar; Missing second permanent molar; Missing twelve year molar\n'}


{'id': 'HP_0011058', 'url': 'http://purl.obolibrary.org/obo/HP_0011058', 'lbl': 'Generalized periodontitis', 'desc': 'label: Generalized periodontitis\ndefinition : A generalized form of periodontitis.\nsynonyms :Generalised gum disease; Generalized gum disease; Widespread gum disease; Generalised periodontal disease; Generalised periodontitis; Generalized periodontal disease\n'}


{'id': 'HP_0011059', 'url': 'http://purl.obolibrary.org/obo/HP_0011059', 'lbl': 'Localized periodontitis', 'desc': 'label: Localized periodontitis\ndefinition : A localized form of periodontitis.\nsynonyms :Limited area of gum disease; Localised gum disease; Localized gum disease; Localised periodontal disease; Localised periodontitis; Localized periodontal disease\n'}


{'id': 'HP_0011060', 'url': 'http://purl.obolibrary.org/obo/HP_0011060', 'lbl': 'Dentinogenesis imperfecta limited to primary teeth', 'desc': 'label: Dentinogenesis imperfecta limited to primary teeth\ndefinition : Developmental dysplasia of dentin affecting only the primary dentition.\nsynonyms :Dentinogenesis imperfecta of baby teeth\n'}


{'id': 'HP_0011061', 'url': 'http://purl.obolibrary.org/obo/HP_0011061', 'lbl': 'Abnormality of dental structure', 'desc': 'label: Abnormality of dental structure\ndefinition : An abnormality of the structure or composition of the teeth.\nsynonyms :Abnormality of tooth part; Abnormality of tooth structure\n'}


{'id': 'HP_0011062', 'url': 'http://purl.obolibrary.org/obo/HP_0011062', 'lbl': 'Misalignment of incisors', 'desc': 'label: Misalignment of incisors\ndefinition : Misaligned incisor.\nsynonyms :Abnormality of position of incisors; Malposition of incisors; Abnormality of alignment of incisors; Crooked front teeth; Crooked incisors; Misalignment of incisors\n'}


{'id': 'HP_0011063', 'url': 'http://purl.obolibrary.org/obo/HP_0011063', 'lbl': 'Abnormal incisor morphology', 'desc': 'label: Abnormal incisor morphology\ndefinition : An abnormality of morphology of the incisor tooth.\nsynonyms :Abnormality of incisor morphology; Abnormality of shape of incisor\n'}


{'id': 'HP_0011064', 'url': 'http://purl.obolibrary.org/obo/HP_0011064', 'lbl': 'Abnormal number of incisors', 'desc': 'label: Abnormal number of incisors\ndefinition : The presence of an altered number of the incisor teeth.\nsynonyms :Abnormal number of front teeth; Abnormal number of incisors\n'}


{'id': 'HP_0011065', 'url': 'http://purl.obolibrary.org/obo/HP_0011065', 'lbl': 'Conical incisor', 'desc': 'label: Conical incisor\ndefinition : An abnormal conical morphology of the incisor tooth.\nsynonyms :Cone shaped front tooth; Conoid incisor; Peg shaped incisors; Peg-shaped incisors; Shark tooth incisor; Peg shaped front tooth; Pointed front tooth; Pointed incisor\n'}


{'id': 'HP_0011067', 'url': 'http://purl.obolibrary.org/obo/HP_0011067', 'lbl': 'Mesiodens', 'desc': 'label: Mesiodens\ndefinition : A supernumerary tooth in the midline between the maxillary central incisors.\nsynonyms :Extra tooth; Extra tooth in the midline; Median supernumary tooth; Midline supernumary tooth; Mesiodentes\n'}


{'id': 'HP_0011068', 'url': 'http://purl.obolibrary.org/obo/HP_0011068', 'lbl': 'Odontoma', 'desc': 'label: Odontoma\ndefinition : The presence of an odontoma.\nsynonyms :Odontomas\n'}


{'id': 'HP_0011069', 'url': 'http://purl.obolibrary.org/obo/HP_0011069', 'lbl': 'Supernumerary tooth', 'desc': 'label: Supernumerary tooth\ndefinition : The presence of one or more teeth additional to the normal number.\nsynonyms :Extra teeth; Hyperdontia; Increased number of teeth; Increased tooth count; Supernumerary teeth; Supplemental dentition; Supplemental teeth; Tooth, supernumerary; Supernumary dentition; Supernumary teeth; More teeth than normal\n'}


{'id': 'HP_0011070', 'url': 'http://purl.obolibrary.org/obo/HP_0011070', 'lbl': 'Abnormal molar morphology', 'desc': 'label: Abnormal molar morphology\ndefinition : An abnormality of morphology of molar tooth.\nsynonyms :Abnormal shape of molar tooth; Abnormality of molar morphology\n'}


{'id': 'HP_0011071', 'url': 'http://purl.obolibrary.org/obo/HP_0011071', 'lbl': 'Abnormality of permanent molar morphology', 'desc': 'label: Abnormality of permanent molar morphology\ndefinition : An abnormality of morphology of permanent molar.\nsynonyms :Abnormality of shape of adult molar; Abnormality of shape of permanent molar\n'}


{'id': 'HP_0011072', 'url': 'http://purl.obolibrary.org/obo/HP_0011072', 'lbl': 'Rootless teeth', 'desc': 'label: Rootless teeth\ndefinition : \nsynonyms :Absence of tooth root; Agenesis of tooth root; Aplasia of tooth root; Missing tooth root; Rootless teeth; Teeth without roots; Tooth with dentin dysplasia type i\n'}


{'id': 'HP_0011073', 'url': 'http://purl.obolibrary.org/obo/HP_0011073', 'lbl': 'Abnormality of dental color', 'desc': 'label: Abnormality of dental color\ndefinition : A developmental defect of tooth color.\nsynonyms :Abnormality of dental color; Abnormality of dental colour; Abnormality of dental shade; Abnormality of tooth color; Abnormality of tooth colour; Abnormality of tooth shade\n'}


{'id': 'HP_0011074', 'url': 'http://purl.obolibrary.org/obo/HP_0011074', 'lbl': 'Localized hypoplasia of dental enamel', 'desc': 'label: Localized hypoplasia of dental enamel\ndefinition : A localized form of developmental hypoplasia of the dental enamel.\nsynonyms :Localised hypoplasia of dental enamel; Localised hypoplasia of tooth enamel; Localized hypoplasia of tooth enamel; Localised dysplasia of tooth enamel; Localized dysplasia of tooth enamel\n'}


{'id': 'HP_0011075', 'url': 'http://purl.obolibrary.org/obo/HP_0011075', 'lbl': 'Green teeth', 'desc': 'label: Green teeth\ndefinition : A green staining of teeth.\nsynonyms :Green colored teeth; Green coloured teeth; Green teeth; Green tooth shade\n'}


{'id': 'HP_0011076', 'url': 'http://purl.obolibrary.org/obo/HP_0011076', 'lbl': 'Abnormality of premolar', 'desc': 'label: Abnormality of premolar\ndefinition : An abnormality of premolar tooth.\nsynonyms :Abnormality of bicuspid; Abnormality of premolar\n'}


{'id': 'HP_0011077', 'url': 'http://purl.obolibrary.org/obo/HP_0011077', 'lbl': 'Abnormality of molar', 'desc': 'label: Abnormality of molar\ndefinition : An abnormality of molar tooth.\nsynonyms :Abnormality of molar\n'}


{'id': 'HP_0011078', 'url': 'http://purl.obolibrary.org/obo/HP_0011078', 'lbl': 'Abnormality of canine', 'desc': 'label: Abnormality of canine\ndefinition : An abnormality of canine tooth.\nsynonyms :Abnormality of canine; Abnormality of eye tooth\n'}


{'id': 'HP_0011079', 'url': 'http://purl.obolibrary.org/obo/HP_0011079', 'lbl': 'Impacted tooth', 'desc': 'label: Impacted tooth\ndefinition : A tooth that has not erupted because of local impediments (overcrowding or fibrous gum overgrowth).\nsynonyms :Buried tooth; Impacted tooth; Retained tooth\n'}


{'id': 'HP_0011080', 'url': 'http://purl.obolibrary.org/obo/HP_0011080', 'lbl': 'Abnormal premolar morphology', 'desc': 'label: Abnormal premolar morphology\ndefinition : An abnormality of morphology of premolar tooth.\nsynonyms :Abnormality of bicuspid morphology; Abnormality of premolar morphology; Abnormality of shape of bicuspid; Abnormality of shape of premolar\n'}


{'id': 'HP_0011081', 'url': 'http://purl.obolibrary.org/obo/HP_0011081', 'lbl': 'Incisor macrodontia', 'desc': 'label: Incisor macrodontia\ndefinition : Increased size of the incisor tooth.\nsynonyms :Hyperplasia of incisor; Hypertrophy of incisor; Increased size of incisor; Large incisor; Increased width of incisor\n'}


{'id': 'HP_0011082', 'url': 'http://purl.obolibrary.org/obo/HP_0011082', 'lbl': 'Conical primary incisor', 'desc': 'label: Conical primary incisor\ndefinition : An abnormal conical morphology of the primary incisor.\nsynonyms :Cone shaped front baby tooth; Conical deciduous incisor; Conoid primary incisor; Primary front shark tooth; Peg shaped front baby tooth; Peg shaped primary incisor; Pointed front baby tooth; Pointed primary incisor\n'}


{'id': 'HP_0011083', 'url': 'http://purl.obolibrary.org/obo/HP_0011083', 'lbl': 'Conical maxillary incisor', 'desc': 'label: Conical maxillary incisor\ndefinition : An abnormal conical morphology of either maxillary primary incisor tooth or maxillary permanent incisor tooth or both.\nsynonyms :Cone shaped maxillary incisor; Cone shaped upper front tooth; Conoid maxillary incisor; Upper front shark tooth; Peg shaped upper front tooth; Pointed maxillary incisor; Pointed upper front tooth\n'}


{'id': 'HP_0011084', 'url': 'http://purl.obolibrary.org/obo/HP_0011084', 'lbl': 'Hypocalcification of dental enamel', 'desc': 'label: Hypocalcification of dental enamel\ndefinition : A form of hypomineralization of enamel characterized by reduced calcification.\nsynonyms :Decreased enamel calcification; Poorly calcified tooth enamel\n'}


{'id': 'HP_0011085', 'url': 'http://purl.obolibrary.org/obo/HP_0011085', 'lbl': 'Hypomature dental enamel', 'desc': 'label: Hypomature dental enamel\ndefinition : A form of hypomineralization of enamel characterized by a chalky appearance of the enamel with orange, brown, or white color.\nsynonyms :Immature tooth enamel; Soft teeth; Soft tooth enamel\n'}


{'id': 'HP_0011086', 'url': 'http://purl.obolibrary.org/obo/HP_0011086', 'lbl': 'Dentinogenesis imperfecta of primary and permanent teeth', 'desc': 'label: Dentinogenesis imperfecta of primary and permanent teeth\ndefinition : Developmental dysplasia of dentin or both the primary dentition and the permanent dentition.\nsynonyms :Dentinogenesis imperfecta of adult and baby teeth; Dentinogenesis imperfecta of both sets of teeth\n'}


{'id': 'HP_0011087', 'url': 'http://purl.obolibrary.org/obo/HP_0011087', 'lbl': 'Talon cusp', 'desc': 'label: Talon cusp\ndefinition : Talon cusp is an accessory cusp located near the cingulum (the portion of the lingual or palatal aspect of the tooth that forms a convex protuberance at the cervical third of the anatomic crown).\nsynonyms :Extra cusp on inside of front tooth; Dens evaginatus; Talon cusps\n'}


{'id': 'HP_0011088', 'url': 'http://purl.obolibrary.org/obo/HP_0011088', 'lbl': 'Dens in dente', 'desc': 'label: Dens in dente\ndefinition : An abnormality of the incisor characterized by invagination of the enamel, giving a radiographic appearance that suggests a tooth within a tooth.\nsynonyms :Dens invaginatus; Tooth within a tooth\n'}


{'id': 'HP_0011089', 'url': 'http://purl.obolibrary.org/obo/HP_0011089', 'lbl': 'Double tooth', 'desc': 'label: Double tooth\ndefinition : Fusion of two adjacent teeth.\nsynonyms :Conjoined teeth; Double tooth; Teeth, double; Twinning tooth\n'}


{'id': 'HP_0011090', 'url': 'http://purl.obolibrary.org/obo/HP_0011090', 'lbl': 'Fused teeth', 'desc': 'label: Fused teeth\ndefinition : The union of two separately developing tooth germs typically leading to one less tooth than normal in the affected dental arch.\nsynonyms :Fused teeth; Fusion of teeth; Joined teeth\n'}


{'id': 'HP_0011091', 'url': 'http://purl.obolibrary.org/obo/HP_0011091', 'lbl': 'Gemination', 'desc': 'label: Gemination\ndefinition : The development of two teeth from a single tooth bud, leading to a larger fused tooth.\nsynonyms :Gemination of tooth; Splitting of crown of tooth\n'}


{'id': 'HP_0011092', 'url': 'http://purl.obolibrary.org/obo/HP_0011092', 'lbl': 'Mulberry molar', 'desc': 'label: Mulberry molar\ndefinition : Mulberry molars are irregular teeth generally affecting the first molars and are characterized by a grossly deformed crown imitating, as the name implies, the surface of a mulberry.\nsynonyms :Syphilitic permanent first molar\n'}


{'id': 'HP_0011093', 'url': 'http://purl.obolibrary.org/obo/HP_0011093', 'lbl': 'Molarization of premolar', 'desc': 'label: Molarization of premolar\ndefinition : Increased size and molar morphology of premolar tooth.\nsynonyms :Molar shape of bicuspid; Molar shape of premolar; Molarization of bicuspid; Enlarged premolar; Increased size of premolar\n'}


{'id': 'HP_0011094', 'url': 'http://purl.obolibrary.org/obo/HP_0011094', 'lbl': 'Increased overbite', 'desc': 'label: Increased overbite\ndefinition : Maxillary teeth cover the mandibular teeth when biting to an increased degree. The feature is defined as a vertical overlap of the maxillary incisors over the mandibular incisors that exceeds 2 mm.\nsynonyms :Increased overlap of upper and lower incisors; Overbite; Supraocclusion; Deep bite; Deep overbite; Scissors bite\n'}


{'id': 'HP_0011095', 'url': 'http://purl.obolibrary.org/obo/HP_0011095', 'lbl': 'Overjet', 'desc': 'label: Overjet\ndefinition : An abnormal anteroposterior extension of the maxillary teeth beyond the plane of the mandibular teeth upon jaw closure.\nsynonyms :Abnormality of horizontal incisor relationship; Protrusion of upper teeth in front of lower teeth; Buck teeth; Protrusion of the maxillary incisors; Upper teeth sticking out forward\n'}


{'id': 'HP_0011096', 'url': 'http://purl.obolibrary.org/obo/HP_0011096', 'lbl': 'Peripheral demyelination', 'desc': 'label: Peripheral demyelination\ndefinition : A loss of myelin from the internode regions along myelinated nerve fibers of the peripheral nervous system.\nsynonyms :Demyelination\n'}


{'id': 'HP_0011097', 'url': 'http://purl.obolibrary.org/obo/HP_0011097', 'lbl': 'Epileptic spasm', 'desc': 'label: Epileptic spasm\ndefinition : A sudden flexion, extension, or mixed extension-flexion of predominantly proximal and truncal muscles that is usually more sustained than a myoclonic movement but not as sustained as a tonic seizure. Limited forms may occur: Grimacing, head nodding, or subtle eye movements. Epileptic spasms frequently occur in clusters. Infantile spasms are the best known form, but spasms can occur at all ages\nsynonyms :Epileptic spasms; Salaam convulsion; Salaam convulsions; Salaam seizure; Salaam seizures; West syndrome\n'}


{'id': 'HP_0011098', 'url': 'http://purl.obolibrary.org/obo/HP_0011098', 'lbl': 'Speech apraxia', 'desc': 'label: Speech apraxia\ndefinition : A type of apraxia that is characterized by difficulty or inability to execute speech movements because of problems with coordination and motor problems, leading to incorrect articulation. An increase of errors with increasing word and phrase length may occur.\nsynonyms :Apraxia of speech; Verbal dyspraxia; Speech dyspraxia\n'}


{'id': 'HP_0011099', 'url': 'http://purl.obolibrary.org/obo/HP_0011099', 'lbl': 'Spastic hemiparesis', 'desc': 'label: Spastic hemiparesis\ndefinition : Unilateral paresis (weakness) with spasticity of the affected muscles and increased tendon reflexes.\nsynonyms :Spastic hemiplegia\n'}


{'id': 'HP_0011100', 'url': 'http://purl.obolibrary.org/obo/HP_0011100', 'lbl': 'Intestinal atresia', 'desc': 'label: Intestinal atresia\ndefinition : An abnormal closure, or atresia of the tubular structure of the intestine.\nsynonyms :\n'}


{'id': 'HP_0011102', 'url': 'http://purl.obolibrary.org/obo/HP_0011102', 'lbl': 'Ileal atresia', 'desc': 'label: Ileal atresia\ndefinition : An abnormal closure, or atresia of the tubular structure of the ileum.\nsynonyms :\n'}


{'id': 'HP_0011103', 'url': 'http://purl.obolibrary.org/obo/HP_0011103', 'lbl': 'Abnormal left ventricular outflow tract morphology', 'desc': 'label: Abnormal left ventricular outflow tract morphology\ndefinition : An abnormality of the outflow tract of the left ventricle.\nsynonyms :Abnormality of the left ventricular outflow tract\n'}


{'id': 'HP_0011104', 'url': 'http://purl.obolibrary.org/obo/HP_0011104', 'lbl': 'Abnormality of blood volume homeostasis', 'desc': 'label: Abnormality of blood volume homeostasis\ndefinition : An abnormality in the amount of volume occupied by intravascular blood.\nsynonyms :\n'}


{'id': 'HP_0011105', 'url': 'http://purl.obolibrary.org/obo/HP_0011105', 'lbl': 'Hypervolemia', 'desc': 'label: Hypervolemia\ndefinition : An increase in the amount of intravascular fluid, particularly in the volume of the circulating blood.\nsynonyms :Fluid overload in blood\n'}


{'id': 'HP_0011106', 'url': 'http://purl.obolibrary.org/obo/HP_0011106', 'lbl': 'Hypovolemia', 'desc': 'label: Hypovolemia\ndefinition : An decrease in the amount of intravascular fluid, particularly in the volume of the circulating blood.\nsynonyms :Depleted blood volume\n'}


{'id': 'HP_0011107', 'url': 'http://purl.obolibrary.org/obo/HP_0011107', 'lbl': 'Recurrent aphthous stomatitis', 'desc': 'label: Recurrent aphthous stomatitis\ndefinition : Recurrent episodes of ulceration of the oral mucosa, typically presenting as painful, sharply circumscribed fibrin-covered mucosal defects with a hyperemic border.\nsynonyms :Recurrent canker sores; Recurrent oral aphthae; Aphthous stomatitis; Buccal aphthous ulcers; Recurrent aphthous ulcers\n'}


{'id': 'HP_0011108', 'url': 'http://purl.obolibrary.org/obo/HP_0011108', 'lbl': 'Recurrent sinusitis', 'desc': 'label: Recurrent sinusitis\ndefinition : A recurrent form of sinusitis.\nsynonyms :Sinusitis, recurrent; Recurrent sinus disease\n'}


{'id': 'HP_0011109', 'url': 'http://purl.obolibrary.org/obo/HP_0011109', 'lbl': 'Chronic sinusitis', 'desc': 'label: Chronic sinusitis\ndefinition : A chronic form of sinusitis.\nsynonyms :Chronic sinus disease; Sinusitis, chronic\n'}


{'id': 'HP_0011110', 'url': 'http://purl.obolibrary.org/obo/HP_0011110', 'lbl': 'Recurrent tonsillitis', 'desc': 'label: Recurrent tonsillitis\ndefinition : Inflammation of the tonsils that has occurred repeatedly. The definition of recurrent may vary somewhat, but the criteria used recently as a measure of severity were five or more episodes of true tonsillitis per year, symptoms recurring for at least a year, and episodes that are disabling and that prevent normal functioning. In some cases recurrent tonsillitis may be related to immunosusceptibility. Evidence exists for a genetic predisposition for recurrent tonsillitis.\nsynonyms :Recurrent inflammation of tonsils\n'}


{'id': 'HP_0011111', 'url': 'http://purl.obolibrary.org/obo/HP_0011111', 'lbl': 'Abnormality of immune serum protein physiology', 'desc': 'label: Abnormality of immune serum protein physiology\ndefinition : An abnormality of the concentration or function of circulating immune proteins.\nsynonyms :\n'}


{'id': 'HP_0011112', 'url': 'http://purl.obolibrary.org/obo/HP_0011112', 'lbl': 'Abnormality of serum cytokine level', 'desc': 'label: Abnormality of serum cytokine level\ndefinition : Abnormality of the cytokine levels in the blood, i.e., an abnormality of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells.\nsynonyms :\n'}


{'id': 'HP_0011113', 'url': 'http://purl.obolibrary.org/obo/HP_0011113', 'lbl': 'Abnormality of cytokine secretion', 'desc': 'label: Abnormality of cytokine secretion\ndefinition : An abnormality in the production or cellular release of a cytokine (i.e., any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells).\nsynonyms :\n'}


{'id': 'HP_0011114', 'url': 'http://purl.obolibrary.org/obo/HP_0011114', 'lbl': 'Defective production of NFKB1-dependent cytokines', 'desc': 'label: Defective production of NFKB1-dependent cytokines\ndefinition : An impairment in the production by leukocytes of NFKB1-dependent cytokines such as tumor necrosis factor-alpha and interferon-alpha.\nsynonyms :\n'}


{'id': 'HP_0011115', 'url': 'http://purl.obolibrary.org/obo/HP_0011115', 'lbl': 'Abnormality of chemokine secretion', 'desc': 'label: Abnormality of chemokine secretion\ndefinition : An abnormality in the production or cellular release of a chemokine (a class of cytokines).\nsynonyms :\n'}


{'id': 'HP_0011116', 'url': 'http://purl.obolibrary.org/obo/HP_0011116', 'lbl': 'Abnormality of interferon secretion', 'desc': 'label: Abnormality of interferon secretion\ndefinition : An abnormality in the production or cellular release of interferons (a class of cytokines).\nsynonyms :\n'}


{'id': 'HP_0011117', 'url': 'http://purl.obolibrary.org/obo/HP_0011117', 'lbl': 'Abnormality of interleukin secretion', 'desc': 'label: Abnormality of interleukin secretion\ndefinition : An abnormality in the production or cellular release of interleukins (a class of cytokines).\nsynonyms :Abnormality of IL secretion\n'}


{'id': 'HP_0011118', 'url': 'http://purl.obolibrary.org/obo/HP_0011118', 'lbl': 'Abnormality of tumor necrosis factor secretion', 'desc': 'label: Abnormality of tumor necrosis factor secretion\ndefinition : An abnormality in the production or cellular release of tumor necrosis factor.\nsynonyms :Abnormality of cachectin secretion; Abnormality of cachexin secretion; Abnormality of tumour necrosis factor secretion\n'}


{'id': 'HP_0011119', 'url': 'http://purl.obolibrary.org/obo/HP_0011119', 'lbl': 'Abnormal nasal dorsum morphology', 'desc': 'label: Abnormal nasal dorsum morphology\ndefinition : An abnormality of the nasal dorsum, also known as the nasal ridge.\nsynonyms :Abnormality of the dorsum of nose; Abnormality of the nasal dorsum; Abnormality of the nasal ridge; Anomaly of the nasal ridge; Abnormal morphology of dorsum of nose; Crooked dorsum of nose; Crooked nasal dorsum; Crooked nasal ridge; Deformity of the dorsum of the nose; Deformity of the nasal dorsum; Deformity of the nasal ridge; Malformation of the dorsum of nose; Malformation of the nasal dorsum; Malformation of the nasal ridge\n'}


{'id': 'HP_0011120', 'url': 'http://purl.obolibrary.org/obo/HP_0011120', 'lbl': 'Concave nasal ridge', 'desc': "label: Concave nasal ridge\ndefinition : Nasal ridge curving posteriorly to an imaginary line that connects the nasal root and tip.\nsynonyms :Boxer's nasal deformity; Boxer's nose deformity; Concave dorsum of nose; Concave nasal dorsum; Saddle nose; Saddle shaped nasal dorsum; Ski jump nose; Saddle nose deformity\n"}


{'id': 'HP_0011121', 'url': 'http://purl.obolibrary.org/obo/HP_0011121', 'lbl': 'Abnormality of skin morphology', 'desc': 'label: Abnormality of skin morphology\ndefinition : Any morphological abnormality of the skin.\nsynonyms :Abnormal skin morphology; Abnormal skin structure\n'}


{'id': 'HP_0011122', 'url': 'http://purl.obolibrary.org/obo/HP_0011122', 'lbl': 'Abnormality of skin physiology', 'desc': 'label: Abnormality of skin physiology\ndefinition : Any abnormality of the physiological function of the skin.\nsynonyms :Abnormality of skin physiology\n'}


{'id': 'HP_0011123', 'url': 'http://purl.obolibrary.org/obo/HP_0011123', 'lbl': 'Inflammatory abnormality of the skin', 'desc': 'label: Inflammatory abnormality of the skin\ndefinition : The presence of inflammation of the skin. That is, an abnormality of the skin resulting from the local accumulation of fluid, plasma proteins, and leukocytes.\nsynonyms :Abnormal tendency to infections of the skin; Inflammatory abnormality of the skin; Skin inflammation; Dermatitis; Inflammatory skin disease\n'}


{'id': 'HP_0011124', 'url': 'http://purl.obolibrary.org/obo/HP_0011124', 'lbl': 'Abnormal epidermal morphology', 'desc': 'label: Abnormal epidermal morphology\ndefinition : An abnormality of the morphology of the epidermis.\nsynonyms :Abnormality of epidermal morphology\n'}


{'id': 'HP_0011125', 'url': 'http://purl.obolibrary.org/obo/HP_0011125', 'lbl': 'Abnormality of dermal melanosomes', 'desc': 'label: Abnormality of dermal melanosomes\ndefinition : An abnormality of the melanosomes, i.e., of the cellular organelles in which melanin pigments are synthesized and stored within melanocytes (the cells that produce pigment in the dermis).\nsynonyms :\n'}


{'id': 'HP_0011126', 'url': 'http://purl.obolibrary.org/obo/HP_0011126', 'lbl': 'Nephroptosis', 'desc': 'label: Nephroptosis\ndefinition : A significant descent of the kidney as the patient moves from the supine to the erect position.\nsynonyms :Floating kidney; Renal ptosis\n'}


{'id': 'HP_0011127', 'url': 'http://purl.obolibrary.org/obo/HP_0011127', 'lbl': 'Perioral eczema', 'desc': 'label: Perioral eczema\ndefinition : A type of eczema that occurs in the lips and perioral area.\nsynonyms :Eczema around the mouth\n'}


{'id': 'HP_0011128', 'url': 'http://purl.obolibrary.org/obo/HP_0011128', 'lbl': 'Acute esophageal necrosis', 'desc': "label: Acute esophageal necrosis\ndefinition : A condition characterized by necrosis of the mucosal and submucosal layers of the esophagus not related to ingestion of caustic or other injurious agents. Endoscopically, there is a dark lesion ('black esophagus') distributed in a circumferential manner in the distal one-third of the esophagus with or without exudates. There is involvement of the distal esophagus ending sharply at the gastroesophageal junction.\nsynonyms :\n"}


{'id': 'HP_0011129', 'url': 'http://purl.obolibrary.org/obo/HP_0011129', 'lbl': 'Bilateral fetal pyelectasis', 'desc': 'label: Bilateral fetal pyelectasis\ndefinition : A bilateral form of fetal pyelectasis.\nsynonyms :Bilateral fetal pyelectasia; Bilateral foetal pyelectasia; Bilateral foetal pyelectasis\n'}


{'id': 'HP_0011130', 'url': 'http://purl.obolibrary.org/obo/HP_0011130', 'lbl': 'Abnormal renal calyx morphology', 'desc': 'label: Abnormal renal calyx morphology\ndefinition : Any abnormality of the morphology of the major calices or minor calices of the kidney.\nsynonyms :Abnormality of renal calyx morphology\n'}


{'id': 'HP_0011131', 'url': 'http://purl.obolibrary.org/obo/HP_0011131', 'lbl': 'Perianal dermatitis', 'desc': 'label: Perianal dermatitis\ndefinition : The presence of a rash (change of color and texture) of the perianal skin.\nsynonyms :Perianal rash\n'}


{'id': 'HP_0011132', 'url': 'http://purl.obolibrary.org/obo/HP_0011132', 'lbl': 'Chronic furunculosis', 'desc': 'label: Chronic furunculosis\ndefinition : A furuncle (boil) is a skin infection involving an entire hair follicle and nearby skin tissue. Chronic furunculosis refers to recurrent episodes of furuncles, often caused by recurrent staphylococcus infection.\nsynonyms :\n'}


{'id': 'HP_0011133', 'url': 'http://purl.obolibrary.org/obo/HP_0011133', 'lbl': 'Increased sensitivity to ionizing radiation', 'desc': 'label: Increased sensitivity to ionizing radiation\ndefinition : An abnormally increased sensitivity to the effects of ionizing radiation.\nsynonyms :Increased sensitivity to ionising radiation\n'}


{'id': 'HP_0011134', 'url': 'http://purl.obolibrary.org/obo/HP_0011134', 'lbl': 'Low-grade fever', 'desc': 'label: Low-grade fever\ndefinition : Mild fever that does not exceed 38.5 degrees centigrade.\nsynonyms :Low-grade fever; Mild fever\n'}


{'id': 'HP_0011135', 'url': 'http://purl.obolibrary.org/obo/HP_0011135', 'lbl': 'Aplasia/Hypoplasia of the sweat glands', 'desc': 'label: Aplasia/Hypoplasia of the sweat glands\ndefinition : Absence or developmental hypoplasia of the sweat glands.\nsynonyms :Absent/small sweat glands; Absent/underdeveloped sweat glands\n'}


{'id': 'HP_0011136', 'url': 'http://purl.obolibrary.org/obo/HP_0011136', 'lbl': 'Aplasia of the sweat glands', 'desc': 'label: Aplasia of the sweat glands\ndefinition : Absence of the sweat glands.\nsynonyms :Absent sweat glands; Lack of sweat glands\n'}


{'id': 'HP_0011137', 'url': 'http://purl.obolibrary.org/obo/HP_0011137', 'lbl': 'Non-pruritic urticaria', 'desc': 'label: Non-pruritic urticaria\ndefinition : Pale reddish slightly elevated papules and plaques of 0.5-3 cm in diameter and not accompanied by pruritus.\nsynonyms :Non-itchy hives\n'}


{'id': 'HP_0011138', 'url': 'http://purl.obolibrary.org/obo/HP_0011138', 'lbl': 'Abnormality of skin adnexa morphology', 'desc': 'label: Abnormality of skin adnexa morphology\ndefinition : An abnormality of the skin adnexa (skin appendages), which are specialized skin structures located within the dermis and focally within the subcutaneous fatty tissue, comprising three histologically distinct structures: (1) the pilosebaceous unit (hair follicle and sebaceous glands); (2) the eccrine sweat glands; and (3) the apocrine glands.\nsynonyms :Abnormal skin appendage\n'}


{'id': 'HP_0011139', 'url': 'http://purl.obolibrary.org/obo/HP_0011139', 'lbl': 'Gastric duplication', 'desc': 'label: Gastric duplication\ndefinition : Gastric duplication is a usually cystic malformation of gastrointestinal tract, usually attached to the greater curvature of the stomach and has no communication with the stomach.\nsynonyms :Gastric duplication cyst\n'}


{'id': 'HP_0011140', 'url': 'http://purl.obolibrary.org/obo/HP_0011140', 'lbl': 'Gastrointestinal duplication', 'desc': 'label: Gastrointestinal duplication\ndefinition : A spherical hollow structure with a smooth muscle coat, lined by a mucous membrane, and attached to any part of the gastrointestinal tract, from the base of the tongue to the anus.\nsynonyms :GI duplication\n'}


{'id': 'HP_0011141', 'url': 'http://purl.obolibrary.org/obo/HP_0011141', 'lbl': 'Age-related cataract', 'desc': 'label: Age-related cataract\ndefinition : A type of cataract (opacification of the lens) that forms during the course of aging.\nsynonyms :Clouding of the lens of the eye with age\n'}


{'id': 'HP_0011142', 'url': 'http://purl.obolibrary.org/obo/HP_0011142', 'lbl': 'Age-related nuclear cataract', 'desc': 'label: Age-related nuclear cataract\ndefinition : A type of age-related cataract that primarily affects the nucleus of the lens.\nsynonyms :\n'}


{'id': 'HP_0011143', 'url': 'http://purl.obolibrary.org/obo/HP_0011143', 'lbl': 'Age-related cortical cataract', 'desc': 'label: Age-related cortical cataract\ndefinition : A type of age-related cataract that primarily affects the cortex of the lens.\nsynonyms :\n'}


{'id': 'HP_0011144', 'url': 'http://purl.obolibrary.org/obo/HP_0011144', 'lbl': 'Age-related posterior subcapsular cataract', 'desc': 'label: Age-related posterior subcapsular cataract\ndefinition : A type of age-related cataract consisting of granular opacities occurring mainly in the central posterior cortex just under the posterior capsule.\nsynonyms :\n'}


{'id': 'HP_0011145', 'url': 'http://purl.obolibrary.org/obo/HP_0011145', 'lbl': 'Symptomatic seizures', 'desc': 'label: Symptomatic seizures\ndefinition : A seizure that occurs in the context of a brain insult (systemic, toxic, or metabolic) and may not recur when the underlying cause has been removed or the acute phase has elapsed.\nsynonyms :\n'}


{'id': 'HP_0011146', 'url': 'http://purl.obolibrary.org/obo/HP_0011146', 'lbl': 'Dialeptic seizure', 'desc': 'label: Dialeptic seizure\ndefinition : A dialeptic seizure is a type of seizure characterised predominantly by reduced responsiveness or awareness and with subsequent at least partial amnesia of the event.\nsynonyms :Behavioral arrest seizure with impairment of awareness irrespective of onset; Behavioural arrest seizure with impairment of awareness irrespective of onset; Unknown onset behavioral arrest seizure with impairment of awareness; Unknown onset behavioural arrest seizure with impairment of awareness\n'}


{'id': 'HP_0011147', 'url': 'http://purl.obolibrary.org/obo/HP_0011147', 'lbl': 'Typical absence seizure', 'desc': 'label: Typical absence seizure\ndefinition : A typical absence seizure is a type of generalised non-motor (absence) seizure characterised by its sudden onset, interruption of ongoing activities, a blank stare, possibly a brief upward deviation of the eyes. Usually the patient will be unresponsive when spoken to. Duration is a few seconds to half a minute with very rapid recovery. Although not always available, an EEG would usually show 3 Hz generalized epileptiform discharges during the event.\nsynonyms :Typical absence; Typical absence seizures\n'}


{'id': 'HP_0011148', 'url': 'http://purl.obolibrary.org/obo/HP_0011148', 'lbl': 'obsolete Absence seizures with special features', 'desc': 'label: obsolete Absence seizures with special features\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011149', 'url': 'http://purl.obolibrary.org/obo/HP_0011149', 'lbl': 'Absence seizure with eyelid myoclonia', 'desc': 'label: Absence seizure with eyelid myoclonia\ndefinition : An absence with eyelid myoclonia seizure is a type of generalized non-motor (absence) seizure characterised by forced upward jerking of the eyelids during an absence seizure.\nsynonyms :Absence seizures with eyelid myoclonia\n'}


{'id': 'HP_0011150', 'url': 'http://purl.obolibrary.org/obo/HP_0011150', 'lbl': 'Myoclonic absence seizure', 'desc': 'label: Myoclonic absence seizure\ndefinition : Myoclonic absence seizure is a type of generalized non-motor (absence) seizure characterised by an interruption of ongoing activities, a blank stare and rhythmic three-per-second myoclonic movements, causing ratcheting abduction of the upper limbs leading to progressive arm elevation, and associated with 3 Hz generalized spike-wave discharges on the electroencephalogram. Duration is typically 10-60 s. Whilst impairment of consciousness may not be obvious the ILAE classified this seizure as a generalized non-motor seizure in 2017.\nsynonyms :Myoclonic absence; Myoclonic absences\n'}


{'id': 'HP_0011151', 'url': 'http://purl.obolibrary.org/obo/HP_0011151', 'lbl': 'Atypical absence status epilepticus', 'desc': 'label: Atypical absence status epilepticus\ndefinition : Atypical absence status epilepticus is a type of generalized non-convulsive status epilepticus without coma that is semiologically a prolonged atypical absence seizure.\nsynonyms :Obtundation status\n'}


{'id': 'HP_0011152', 'url': 'http://purl.obolibrary.org/obo/HP_0011152', 'lbl': 'Early onset absence seizures', 'desc': 'label: Early onset absence seizures\ndefinition : Typical absence seizures starting before the age of 4 years.\nsynonyms :Early onset petit mal seizures\n'}