{'id': 'HP_0004529', 'url': 'http://purl.obolibrary.org/obo/HP_0004529', 'lbl': 'Atrophic, patchy alopecia', 'desc': 'label: Atrophic, patchy alopecia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004532', 'url': 'http://purl.obolibrary.org/obo/HP_0004532', 'lbl': 'Sacral hypertrichosis', 'desc': 'label: Sacral hypertrichosis\ndefinition : Excessive, increased hair growth located in the sacral region.\nsynonyms :\n'}


{'id': 'HP_0004535', 'url': 'http://purl.obolibrary.org/obo/HP_0004535', 'lbl': 'Anterior cervical hypertrichosis', 'desc': "label: Anterior cervical hypertrichosis\ndefinition : Anterior cervical hypertrichosis (ACH) or 'hairy throat' refers to the presence of a tuft of terminal hair on the anterior neck, just above the laryngeal prominence.\nsynonyms :Congenital cervical hypertrichosis; Hypertrichosis, congenital anterior cervical\n"}


{'id': 'HP_0004540', 'url': 'http://purl.obolibrary.org/obo/HP_0004540', 'lbl': 'Congenital, generalized hypertrichosis', 'desc': 'label: Congenital, generalized hypertrichosis\ndefinition : A confluent, generalized overgrowth of silvery blonde to gray lanugo hair at birth.\nsynonyms :Congenital generalised hypertrichosis; Congenital generalized hypertrichosis; Congenital, generalised hypertrichosis; Hypertrichosis universalis\n'}


{'id': 'HP_0004544', 'url': 'http://purl.obolibrary.org/obo/HP_0004544', 'lbl': 'obsolete Pointed frontal hairline', 'desc': 'label: obsolete Pointed frontal hairline\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004552', 'url': 'http://purl.obolibrary.org/obo/HP_0004552', 'lbl': 'Scarring alopecia of scalp', 'desc': 'label: Scarring alopecia of scalp\ndefinition : \nsynonyms :Cicatricial alopecia; Hair loss on scalp from scarring condition\n'}


{'id': 'HP_0004554', 'url': 'http://purl.obolibrary.org/obo/HP_0004554', 'lbl': 'Generalized hypertrichosis', 'desc': 'label: Generalized hypertrichosis\ndefinition : Generalized excessive, abnormal hairiness.\nsynonyms :Generalised hypertrichosis\n'}


{'id': 'HP_0004557', 'url': 'http://purl.obolibrary.org/obo/HP_0004557', 'lbl': 'Anterior vertebral fusion', 'desc': 'label: Anterior vertebral fusion\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004558', 'url': 'http://purl.obolibrary.org/obo/HP_0004558', 'lbl': 'Cervical platyspondyly', 'desc': 'label: Cervical platyspondyly\ndefinition : A flattened vertebral body shape with reduced distance between the vertebral endplates affecting the cervical spine.\nsynonyms :Flattened cervical vertebral bodies\n'}


{'id': 'HP_0004562', 'url': 'http://purl.obolibrary.org/obo/HP_0004562', 'lbl': 'Beaking of vertebral bodies T12-L3', 'desc': 'label: Beaking of vertebral bodies T12-L3\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004563', 'url': 'http://purl.obolibrary.org/obo/HP_0004563', 'lbl': 'Increased spinal bone density', 'desc': 'label: Increased spinal bone density\ndefinition : Increased bone density affecting the bones of the spine (vertebral column).\nsynonyms :Increased density of spinal bone; Ivory spinal bone; Compact spinal bone; Concrete spinal bone; Dense spinal bone; Eburnation of spinal bone; Increased spinal bone density Z-score; Sclerosis of spinal bone\n'}


{'id': 'HP_0004565', 'url': 'http://purl.obolibrary.org/obo/HP_0004565', 'lbl': 'Severe platyspondyly', 'desc': 'label: Severe platyspondyly\ndefinition : \nsynonyms :platyspondyly, extreme\n'}


{'id': 'HP_0004566', 'url': 'http://purl.obolibrary.org/obo/HP_0004566', 'lbl': 'Pear-shaped vertebrae', 'desc': 'label: Pear-shaped vertebrae\ndefinition : Bulbous appearance of the anterior vertebral bodies, such that the vertebral bodies have the greatest vertical height anteriorly as well as bulbous anterior superior-inferior contours.\nsynonyms :Pear-shaped vertebral bodies\n'}


{'id': 'HP_0004568', 'url': 'http://purl.obolibrary.org/obo/HP_0004568', 'lbl': 'Beaking of vertebral bodies', 'desc': 'label: Beaking of vertebral bodies\ndefinition : Anterior tongue-like protrusions of the vertebral bodies.\nsynonyms :Anterior beaking of vertebrae; Anterior beaking of vertebral bodies; Beaked vertebral bodies; Vertebral tongue-like protrusion; anterior beaking\n'}


{'id': 'HP_0004570', 'url': 'http://purl.obolibrary.org/obo/HP_0004570', 'lbl': 'Increased vertebral height', 'desc': 'label: Increased vertebral height\ndefinition : Increased top to bottom height of vertebral bodies.\nsynonyms :Tall vertebral bodies\n'}


{'id': 'HP_0004571', 'url': 'http://purl.obolibrary.org/obo/HP_0004571', 'lbl': 'Widening of cervical spinal canal', 'desc': 'label: Widening of cervical spinal canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004573', 'url': 'http://purl.obolibrary.org/obo/HP_0004573', 'lbl': 'Anterior wedging of T11', 'desc': 'label: Anterior wedging of T11\ndefinition : An abnormality of the shape of the thoracic vertebra T11 such that it is wedge-shaped (narrow towards the front).\nsynonyms :Anterior wedging of the 11th thoracic vertebra; Wedge-shaped 11th thoracic vertebra\n'}


{'id': 'HP_0004575', 'url': 'http://purl.obolibrary.org/obo/HP_0004575', 'lbl': 'Fusion of midcervical facet joints', 'desc': 'label: Fusion of midcervical facet joints\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004576', 'url': 'http://purl.obolibrary.org/obo/HP_0004576', 'lbl': 'Sclerotic vertebral endplates', 'desc': 'label: Sclerotic vertebral endplates\ndefinition : Sclerosis (increased density) affecting vertebral end plates.\nsynonyms :Endplate sclerosis\n'}


{'id': 'HP_0004580', 'url': 'http://purl.obolibrary.org/obo/HP_0004580', 'lbl': 'Anterior scalloping of vertebral bodies', 'desc': 'label: Anterior scalloping of vertebral bodies\ndefinition : An excessive concavity of the anterior surface of one or more vertebral bodies.\nsynonyms :Anterior scalloping vertebral bodies\n'}


{'id': 'HP_0004581', 'url': 'http://purl.obolibrary.org/obo/HP_0004581', 'lbl': 'Increased anterior vertebral height', 'desc': 'label: Increased anterior vertebral height\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004582', 'url': 'http://purl.obolibrary.org/obo/HP_0004582', 'lbl': 'Irregularity of vertebral bodies', 'desc': 'label: Irregularity of vertebral bodies\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004586', 'url': 'http://purl.obolibrary.org/obo/HP_0004586', 'lbl': 'Biconcave vertebral bodies', 'desc': "label: Biconcave vertebral bodies\ndefinition : Exaggerated concavity of the anterior or posterior surface of the vertebral body, i.e., the upper and lower vertebral endplates are hollowed inward.\nsynonyms :Biconcave 'codfish' vertebrae; Biconcave vertebrae; Codfish vertebrae; Fish vertebrae; Scalloping of vertebral bodies\n"}


{'id': 'HP_0004589', 'url': 'http://purl.obolibrary.org/obo/HP_0004589', 'lbl': 'Dysplasia of second lumbar vertebra', 'desc': 'label: Dysplasia of second lumbar vertebra\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004590', 'url': 'http://purl.obolibrary.org/obo/HP_0004590', 'lbl': 'Hypoplastic sacrum', 'desc': 'label: Hypoplastic sacrum\ndefinition : \nsynonyms :Small sacrum\n'}


{'id': 'HP_0004591', 'url': 'http://purl.obolibrary.org/obo/HP_0004591', 'lbl': 'Disc-like vertebral bodies', 'desc': 'label: Disc-like vertebral bodies\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004592', 'url': 'http://purl.obolibrary.org/obo/HP_0004592', 'lbl': 'Thoracic platyspondyly', 'desc': 'label: Thoracic platyspondyly\ndefinition : A flattened vertebral body shape with reduced distance beween the vertebral endplates affecting the thoracic spine.\nsynonyms :\n'}


{'id': 'HP_0004594', 'url': 'http://purl.obolibrary.org/obo/HP_0004594', 'lbl': 'Hump-shaped mound of bone in central and posterior portions of vertebral endplate', 'desc': 'label: Hump-shaped mound of bone in central and posterior portions of vertebral endplate\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004598', 'url': 'http://purl.obolibrary.org/obo/HP_0004598', 'lbl': 'Supernumerary vertebral ossification centers', 'desc': 'label: Supernumerary vertebral ossification centers\ndefinition : Three ossification sites are present in typical vertebral bodies (C3-L5): a single ossification center in the vertebral body, and one each in the two neural arches. This term applies if there are additional vertebral ossification centers present during the development and maturation of the spine.\nsynonyms :Supernumerary vertebral ossification centres\n'}


{'id': 'HP_0004599', 'url': 'http://purl.obolibrary.org/obo/HP_0004599', 'lbl': 'Absent or minimally ossified vertebral bodies', 'desc': 'label: Absent or minimally ossified vertebral bodies\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004601', 'url': 'http://purl.obolibrary.org/obo/HP_0004601', 'lbl': 'Spina bifida occulta at L5', 'desc': 'label: Spina bifida occulta at L5\ndefinition : The closed form of spina bifida with incomplete closure of the vertebra L5 with intact overlying skin.\nsynonyms :\n'}


{'id': 'HP_0004602', 'url': 'http://purl.obolibrary.org/obo/HP_0004602', 'lbl': 'Cervical C2/C3 vertebral fusion', 'desc': 'label: Cervical C2/C3 vertebral fusion\ndefinition : Fusion of cervical vertebrae at C2 and C3, caused by a failure in the normal segmentation or division of the cervical vertebrae during the early weeks of fetal development, leading to a short neck with a low hairline at the back of the head, and restricted mobility of the upper spine.\nsynonyms :Fusion of cervical vertebrae c2-3; Klippel-Feil anomaly; Klippel-Feil syndrome\n'}


{'id': 'HP_0004603', 'url': 'http://purl.obolibrary.org/obo/HP_0004603', 'lbl': 'Hyperconvex vertebral body endplates', 'desc': 'label: Hyperconvex vertebral body endplates\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004605', 'url': 'http://purl.obolibrary.org/obo/HP_0004605', 'lbl': 'Absent vertebral body mineralization', 'desc': 'label: Absent vertebral body mineralization\ndefinition : A lack of bone mineralization of the vertebral bodies.\nsynonyms :\n'}


{'id': 'HP_0004606', 'url': 'http://purl.obolibrary.org/obo/HP_0004606', 'lbl': 'Unossified vertebral bodies', 'desc': 'label: Unossified vertebral bodies\ndefinition : A lack of ossification of the vertebral bodies.\nsynonyms :\n'}


{'id': 'HP_0004607', 'url': 'http://purl.obolibrary.org/obo/HP_0004607', 'lbl': 'Anterior beaking of lower thoracic vertebrae', 'desc': 'label: Anterior beaking of lower thoracic vertebrae\ndefinition : Anterior tongue-like protrusions of the lower thoracic vertebral bodies.\nsynonyms :\n'}


{'id': 'HP_0004608', 'url': 'http://purl.obolibrary.org/obo/HP_0004608', 'lbl': 'Anteriorly placed odontoid process', 'desc': 'label: Anteriorly placed odontoid process\ndefinition : Anterior mislocalization of the dens of the axis.\nsynonyms :\n'}


{'id': 'HP_0004609', 'url': 'http://purl.obolibrary.org/obo/HP_0004609', 'lbl': 'Patchy distortion of vertebrae', 'desc': 'label: Patchy distortion of vertebrae\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004610', 'url': 'http://purl.obolibrary.org/obo/HP_0004610', 'lbl': 'Lumbar spinal canal stenosis', 'desc': 'label: Lumbar spinal canal stenosis\ndefinition : An abnormal narrowing of the lumbar spinal canal.\nsynonyms :Lumbar spinal stenosis; Narrow lumbar spinal canal\n'}


{'id': 'HP_0004611', 'url': 'http://purl.obolibrary.org/obo/HP_0004611', 'lbl': 'Anterior concavity of thoracic vertebrae', 'desc': 'label: Anterior concavity of thoracic vertebrae\ndefinition : \nsynonyms :Anteriorly concave vertebrae\n'}


{'id': 'HP_0004614', 'url': 'http://purl.obolibrary.org/obo/HP_0004614', 'lbl': 'Spina bifida occulta at S1', 'desc': 'label: Spina bifida occulta at S1\ndefinition : The closed form of spina bifida with incomplete closure of S1 with intact overlying skin.\nsynonyms :\n'}


{'id': 'HP_0004616', 'url': 'http://purl.obolibrary.org/obo/HP_0004616', 'lbl': 'Cleft vertebral arch', 'desc': 'label: Cleft vertebral arch\ndefinition : A discontinuity of the vertebral arch, i.e., of the posterior part of a vertebra.\nsynonyms :Cleft vertebral arches\n'}


{'id': 'HP_0004617', 'url': 'http://purl.obolibrary.org/obo/HP_0004617', 'lbl': 'Butterfly vertebral arch', 'desc': 'label: Butterfly vertebral arch\ndefinition : Butterfly vertebrae have a cleft through the body of the vertebrae and a funnel shape at the ends.\nsynonyms :\n'}


{'id': 'HP_0004618', 'url': 'http://purl.obolibrary.org/obo/HP_0004618', 'lbl': 'Sandwich appearance of vertebral bodies', 'desc': 'label: Sandwich appearance of vertebral bodies\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004619', 'url': 'http://purl.obolibrary.org/obo/HP_0004619', 'lbl': 'Lumbar kyphoscoliosis', 'desc': 'label: Lumbar kyphoscoliosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004621', 'url': 'http://purl.obolibrary.org/obo/HP_0004621', 'lbl': 'Enlarged vertebral pedicles', 'desc': 'label: Enlarged vertebral pedicles\ndefinition : Increased size of the vertebral pedicle.\nsynonyms :Hyperplastic vertebral pedicles\n'}


{'id': 'HP_0004622', 'url': 'http://purl.obolibrary.org/obo/HP_0004622', 'lbl': 'Progressive intervertebral space narrowing', 'desc': 'label: Progressive intervertebral space narrowing\ndefinition : A progressive form of decreased height of the intervertebral disk.\nsynonyms :\n'}


{'id': 'HP_0004625', 'url': 'http://purl.obolibrary.org/obo/HP_0004625', 'lbl': 'Biconvex vertebral bodies', 'desc': 'label: Biconvex vertebral bodies\ndefinition : Presence of abnormal convexity of the upper and lower end plates of the vertebrae, i.e., an exaggerated bulging out of the upper and lower vertebral end plates.\nsynonyms :\n'}


{'id': 'HP_0004626', 'url': 'http://purl.obolibrary.org/obo/HP_0004626', 'lbl': 'Lumbar scoliosis', 'desc': 'label: Lumbar scoliosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004629', 'url': 'http://purl.obolibrary.org/obo/HP_0004629', 'lbl': 'Small cervical vertebral bodies', 'desc': 'label: Small cervical vertebral bodies\ndefinition : Reduced size of cervical vertebrae.\nsynonyms :Small cervical vertebrae\n'}


{'id': 'HP_0004630', 'url': 'http://purl.obolibrary.org/obo/HP_0004630', 'lbl': 'Anterior beaking of thoracic vertebrae', 'desc': 'label: Anterior beaking of thoracic vertebrae\ndefinition : Anterior tongue-like protrusions of thoracic vertebral bodies.\nsynonyms :\n'}


{'id': 'HP_0004631', 'url': 'http://purl.obolibrary.org/obo/HP_0004631', 'lbl': 'Decreased cervical spine flexion due to contractures of posterior cervical muscles', 'desc': 'label: Decreased cervical spine flexion due to contractures of posterior cervical muscles\ndefinition : \nsynonyms :Inability to touch chin to chest; Contracture of post-cervical muscles\n'}


{'id': 'HP_0004632', 'url': 'http://purl.obolibrary.org/obo/HP_0004632', 'lbl': 'Cervical segmentation defect', 'desc': 'label: Cervical segmentation defect\ndefinition : An abnormality related to a defect of vertebral separation of cervical vertebrae during development.\nsynonyms :Cervical spine segmentation defect\n'}


{'id': 'HP_0004633', 'url': 'http://purl.obolibrary.org/obo/HP_0004633', 'lbl': 'Lower thoracic kyphosis', 'desc': 'label: Lower thoracic kyphosis\ndefinition : Over curvature of the lower thoracic region, leading to a round back or if sever to a hump.\nsynonyms :Round mid-back\n'}


{'id': 'HP_0004634', 'url': 'http://purl.obolibrary.org/obo/HP_0004634', 'lbl': 'Cuboid-shaped vertebral bodies', 'desc': 'label: Cuboid-shaped vertebral bodies\ndefinition : \nsynonyms :Cuboid vertebral bodies\n'}


{'id': 'HP_0004635', 'url': 'http://purl.obolibrary.org/obo/HP_0004635', 'lbl': 'Cervical C5/C6 vertebrae fusion', 'desc': 'label: Cervical C5/C6 vertebrae fusion\ndefinition : Fusion of the C5 and C6 cervical vertebrae.\nsynonyms :\n'}


{'id': 'HP_0004637', 'url': 'http://purl.obolibrary.org/obo/HP_0004637', 'lbl': 'Decreased cervical spine mobility', 'desc': 'label: Decreased cervical spine mobility\ndefinition : \nsynonyms :Limited neck movement\n'}


{'id': 'HP_0004639', 'url': 'http://purl.obolibrary.org/obo/HP_0004639', 'lbl': 'Elevated amniotic fluid alpha-fetoprotein', 'desc': 'label: Elevated amniotic fluid alpha-fetoprotein\ndefinition : An elevation of alpha-feto protein measured in the amniotic fluid.\nsynonyms :Elevated amniotic fluid alpha fetal protein; Elevated amniotic fluid alpha foetal protein; Elevated amniotic fluid alpha-1-fetoprotein; Elevated amniotic fluid alpha-fetoglobulin\n'}


{'id': 'HP_0004646', 'url': 'http://purl.obolibrary.org/obo/HP_0004646', 'lbl': 'Hypoplasia of the nasal bone', 'desc': 'label: Hypoplasia of the nasal bone\ndefinition : Underdevelopment of the nasal bone.\nsynonyms :Small nasal bone; Decreased size of nasal bone; Deficiency of nasal bone; Nasal bone hypoplasia; Underdevelopment of nasal bone; Hypotrophic nasal bone\n'}


{'id': 'HP_0004660', 'url': 'http://purl.obolibrary.org/obo/HP_0004660', 'lbl': 'Hypoplasia of facial musculature', 'desc': 'label: Hypoplasia of facial musculature\ndefinition : Underdevelopment of one or more muscles innervated by the facial nerve (the seventh cranial nerve).\nsynonyms :Small facial muscles; Decreased size of facial muscles; Deficiency of facial musculature; Underdevelopment of facial muscles; Atrophy of facial musculature; Hypotrophic facial musculature\n'}


{'id': 'HP_0004661', 'url': 'http://purl.obolibrary.org/obo/HP_0004661', 'lbl': 'Frontalis muscle weakness', 'desc': 'label: Frontalis muscle weakness\ndefinition : Reduced strength of the frontalis muscle (which is located on the forehead).\nsynonyms :Weak frontalis muscle; Weakness of forehead muscle\n'}


{'id': 'HP_0004664', 'url': 'http://purl.obolibrary.org/obo/HP_0004664', 'lbl': 'Facial midline hemangioma', 'desc': 'label: Facial midline hemangioma\ndefinition : Hemangioma, a benign tumor of the vascular endothelial cells, occurring in the midline region of the face.\nsynonyms :\n'}


{'id': 'HP_0004673', 'url': 'http://purl.obolibrary.org/obo/HP_0004673', 'lbl': 'Decreased facial expression', 'desc': 'label: Decreased facial expression\ndefinition : A reduced degree of voluntary and involuntary facial movements involved in responded to others or expressing emotions.\nsynonyms :Decreased facial expression\n'}


{'id': 'HP_0004676', 'url': 'http://purl.obolibrary.org/obo/HP_0004676', 'lbl': 'Prominent supraorbital arches in adult', 'desc': 'label: Prominent supraorbital arches in adult\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004679', 'url': 'http://purl.obolibrary.org/obo/HP_0004679', 'lbl': 'Large tarsal bones', 'desc': 'label: Large tarsal bones\ndefinition : \nsynonyms :Large ankle bones\n'}


{'id': 'HP_0004681', 'url': 'http://purl.obolibrary.org/obo/HP_0004681', 'lbl': 'Deep longitudinal plantar crease', 'desc': 'label: Deep longitudinal plantar crease\ndefinition : Narrow, paramedian longitudinal depressions in the plantar skin of the forefoot.\nsynonyms :Foot crease; Longitudinal groove on soles\n'}


{'id': 'HP_0004684', 'url': 'http://purl.obolibrary.org/obo/HP_0004684', 'lbl': 'Talipes valgus', 'desc': 'label: Talipes valgus\ndefinition : Outward turning of the heel, resulting in clubfoot with the person walking on the inner part of the foot.\nsynonyms :\n'}


{'id': 'HP_0004686', 'url': 'http://purl.obolibrary.org/obo/HP_0004686', 'lbl': 'Short third metatarsal', 'desc': 'label: Short third metatarsal\ndefinition : Underdevelopment of the Third metatarsal bone leading to a short (hypoplastic) third metatarsal bone.\nsynonyms :Hypoplasia of the 3rd metatarsal bone; Short 3rd long bone of foot\n'}


{'id': 'HP_0004688', 'url': 'http://purl.obolibrary.org/obo/HP_0004688', 'lbl': 'Irregular tarsal bones', 'desc': 'label: Irregular tarsal bones\ndefinition : \nsynonyms :Abnormal shape of ankle bones\n'}


{'id': 'HP_0004689', 'url': 'http://purl.obolibrary.org/obo/HP_0004689', 'lbl': 'Short fourth metatarsal', 'desc': 'label: Short fourth metatarsal\ndefinition : Short fourth metatarsal bone.\nsynonyms :Bilateral fourth metatarsal shortening; Short 4th long bone of foot; Short fourth metatarsus; Short fourth metatarsals\n'}


{'id': 'HP_0004690', 'url': 'http://purl.obolibrary.org/obo/HP_0004690', 'lbl': 'Thickened Achilles tendon', 'desc': 'label: Thickened Achilles tendon\ndefinition : An abnormal thickening of the Achilles tendon.\nsynonyms :Thickened Achilles tendon\n'}


{'id': 'HP_0004691', 'url': 'http://purl.obolibrary.org/obo/HP_0004691', 'lbl': '2-3 toe syndactyly', 'desc': 'label: 2-3 toe syndactyly\ndefinition : Syndactyly with fusion of toes two and three.\nsynonyms :2-3 syndactyly of feet; 2-3 toe soft tissue syndactyly; 2-3 toes syndactyly; Syndactyly of second and third toes; Toe syndactyly, 2-3; Webbed 2nd and 3rd toes; partial or complete syndactyly 2nd-3rd toes\n'}


{'id': 'HP_0004692', 'url': 'http://purl.obolibrary.org/obo/HP_0004692', 'lbl': '4-5 toe syndactyly', 'desc': 'label: 4-5 toe syndactyly\ndefinition : Syndactyly with fusion of toes four and five.\nsynonyms :Symmetric syndactyly, toes 4 and 5; Syndactyly of toes 4 and 5; Webbed 4th-5th toes\n'}


{'id': 'HP_0004695', 'url': 'http://purl.obolibrary.org/obo/HP_0004695', 'lbl': 'Calcaneal epiphyseal stippling', 'desc': 'label: Calcaneal epiphyseal stippling\ndefinition : The presence of abnormal punctate (speckled, dot-like) calcifications in the epiphysis of the calcaneus.\nsynonyms :\n'}


{'id': 'HP_0004696', 'url': 'http://purl.obolibrary.org/obo/HP_0004696', 'lbl': 'Talipes cavus equinovarus', 'desc': 'label: Talipes cavus equinovarus\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004699', 'url': 'http://purl.obolibrary.org/obo/HP_0004699', 'lbl': 'Osteoporotic metatarsal', 'desc': 'label: Osteoporotic metatarsal\ndefinition : Decrease in mass and density of the metatarsal bones.\nsynonyms :\n'}


{'id': 'HP_0004704', 'url': 'http://purl.obolibrary.org/obo/HP_0004704', 'lbl': 'Short fifth metatarsal', 'desc': 'label: Short fifth metatarsal\ndefinition : Short (hypoplastic) fifth metatarsal bone.\nsynonyms :Hypoplasia of the fifth metatarsal bone; Short 5th long bone of foot\n'}


{'id': 'HP_0004712', 'url': 'http://purl.obolibrary.org/obo/HP_0004712', 'lbl': 'Renal malrotation', 'desc': 'label: Renal malrotation\ndefinition : An abnormality of the normal developmental rotation of the kidney leading to an abnormal orientation of the kidney.\nsynonyms :Abnormal rotation of the kidneys; Malrotation of the kidney\n'}


{'id': 'HP_0004713', 'url': 'http://purl.obolibrary.org/obo/HP_0004713', 'lbl': 'Reversible renal failure', 'desc': 'label: Reversible renal failure\ndefinition : Acute renal failure with resolution of manifestations.\nsynonyms :Reversible kidney failure; Reversible renal failure\n'}


{'id': 'HP_0004717', 'url': 'http://purl.obolibrary.org/obo/HP_0004717', 'lbl': 'Axial malrotation of the kidney', 'desc': 'label: Axial malrotation of the kidney\ndefinition : An abnormality of the normal developmental rotation of the kidney leading to an abnormal axial orientation of the kidney.\nsynonyms :\n'}


{'id': 'HP_0004719', 'url': 'http://purl.obolibrary.org/obo/HP_0004719', 'lbl': 'Hyperechogenic kidneys', 'desc': 'label: Hyperechogenic kidneys\ndefinition : An increase in amplitude of waves returned in ultrasonography of the kidney, which is generally displayed as increased brightness of the signal.\nsynonyms :Echogenic kidneys; Increased echogenicity of the renal parenchyma\n'}


{'id': 'HP_0004722', 'url': 'http://purl.obolibrary.org/obo/HP_0004722', 'lbl': 'Thickened glomerular basement membrane', 'desc': 'label: Thickened glomerular basement membrane\ndefinition : Prominent glomerular basement membrane (GBM), reflecting an increase in thickness (subjective estimate) of the basal lamina of the glomerulus of the kidney.\nsynonyms :\n'}


{'id': 'HP_0004724', 'url': 'http://purl.obolibrary.org/obo/HP_0004724', 'lbl': 'Calcium nephrolithiasis', 'desc': 'label: Calcium nephrolithiasis\ndefinition : The presence of calcium-containing calculi (stones) in the kidneys.\nsynonyms :Ca kidney stone; Ca nephrolithiasis; Ca2+ kidney stone; Ca2+ nephrolithiasis; Calcium kidney stone\n'}


{'id': 'HP_0004727', 'url': 'http://purl.obolibrary.org/obo/HP_0004727', 'lbl': 'Impaired renal concentrating ability', 'desc': 'label: Impaired renal concentrating ability\ndefinition : A defect in the ability to concentrate the urine.\nsynonyms :Urine concentrating defect; Urine concentration defect\n'}


{'id': 'HP_0004729', 'url': 'http://purl.obolibrary.org/obo/HP_0004729', 'lbl': 'Acute tubulointerstitial nephritis', 'desc': 'label: Acute tubulointerstitial nephritis\ndefinition : Acute inflammation of the kidney affecting the interstitium of the kidneys surrounding the tubules.\nsynonyms :\n'}


{'id': 'HP_0004732', 'url': 'http://purl.obolibrary.org/obo/HP_0004732', 'lbl': 'Impaired renal uric acid clearance', 'desc': 'label: Impaired renal uric acid clearance\ndefinition : A reduction in the ability of the kidneys to remove uric acid from the serum.\nsynonyms :\n'}


{'id': 'HP_0004734', 'url': 'http://purl.obolibrary.org/obo/HP_0004734', 'lbl': 'Renal cortical microcysts', 'desc': 'label: Renal cortical microcysts\ndefinition : Cysts of microscopic size confined to the cortex of the kidney.\nsynonyms :Cortical microcysts; Multiple renal cortical microcysts; Multiple small renal cortical cysts\n'}


{'id': 'HP_0004736', 'url': 'http://purl.obolibrary.org/obo/HP_0004736', 'lbl': 'Crossed fused renal ectopia', 'desc': 'label: Crossed fused renal ectopia\ndefinition : A developmental anomaly in which the kidneys are fused and localized on the same side of the midline. This anomaly is thought to result from disruption of the normal embryologic migration of the kidneys.\nsynonyms :Crossed-fused renal ectopia; Ectopic kidney with fusion\n'}


{'id': 'HP_0004737', 'url': 'http://purl.obolibrary.org/obo/HP_0004737', 'lbl': 'Global glomerulosclerosis', 'desc': 'label: Global glomerulosclerosis\ndefinition : Obliteration of the glomerular capillary lumen by increased collagenous matrix, with or without hyalinosis or foam cells. Sclerosis involves 100% of the glomerular tuft. Relative to other patent glomeruli in the sample, glomerular size is preserved, or increased/decreased by no more than 50%.\nsynonyms :\n'}


{'id': 'HP_0004742', 'url': 'http://purl.obolibrary.org/obo/HP_0004742', 'lbl': 'Abnormal renal collecting system morphology', 'desc': 'label: Abnormal renal collecting system morphology\ndefinition : An abnormality of the renal collecting system.\nsynonyms :Abnormal collecting system; Abnormality of the renal collecting system; Renal collecting system anomalies\n'}


{'id': 'HP_0004743', 'url': 'http://purl.obolibrary.org/obo/HP_0004743', 'lbl': 'Chronic tubulointerstitial nephritis', 'desc': 'label: Chronic tubulointerstitial nephritis\ndefinition : Chronic inflammation of the kidney affecting the interstitium of the kidneys surrounding the tubules.\nsynonyms :\n'}


{'id': 'HP_0004746', 'url': 'http://purl.obolibrary.org/obo/HP_0004746', 'lbl': 'Glomerular subendothelial electron-dense deposits', 'desc': 'label: Glomerular subendothelial electron-dense deposits\ndefinition : Electron dense deposits at the glomerular basement membrane,\nsynonyms :Dense deposit disease; Membranoproliferative glomerulonephritis type II\n'}


{'id': 'HP_0004749', 'url': 'http://purl.obolibrary.org/obo/HP_0004749', 'lbl': 'Atrial flutter', 'desc': 'label: Atrial flutter\ndefinition : A type of atrial arrhythmia characterized by atrial rates of between 240 and 400 beats per minute and some degree of atrioventricular node conduction block. Typically, the ventricular rate is half the atrial rate. In the EKG; atrial flutter waves are observed as sawtooth-like atrial activity. Pathophysiologically, atrial flutter is a form of atrial reentry in which there is a premature electrical impulse creates a self-propagating circuit.\nsynonyms :\n'}


{'id': 'HP_0004751', 'url': 'http://purl.obolibrary.org/obo/HP_0004751', 'lbl': 'Paroxysmal ventricular tachycardia', 'desc': 'label: Paroxysmal ventricular tachycardia\ndefinition : Episodes of ventricular tachycardia that have a sudden onset and ending.\nsynonyms :Episodes of ventricular tachycardia\n'}


{'id': 'HP_0004752', 'url': 'http://purl.obolibrary.org/obo/HP_0004752', 'lbl': 'Congenital atrioventricular dissociation', 'desc': 'label: Congenital atrioventricular dissociation\ndefinition : A form of atrioventricular (AV) dissociation (i.e., the atria and the ventricles are under the control of two separate pacemakers) with congenital onset.\nsynonyms :\n'}


{'id': 'HP_0004754', 'url': 'http://purl.obolibrary.org/obo/HP_0004754', 'lbl': 'Permanent atrial fibrillation', 'desc': 'label: Permanent atrial fibrillation\ndefinition : Atrial fibrillation (AF) that cannot be successfully terminated by cardioversion, and longstanding (more than 1 year) AF, where cardioversion is not indicated or has not been attempted, is termed permanent.\nsynonyms :Chronic atrial fibrillation\n'}


{'id': 'HP_0004755', 'url': 'http://purl.obolibrary.org/obo/HP_0004755', 'lbl': 'Supraventricular tachycardia', 'desc': 'label: Supraventricular tachycardia\ndefinition : Supraventricular tachycardia (SVT) is an abnormally increased heart rate (over 100 beats per minute at rest) with origin above the level of the ventricles.\nsynonyms :SVT; Supraventricular tachyarrhythmia\n'}


{'id': 'HP_0004756', 'url': 'http://purl.obolibrary.org/obo/HP_0004756', 'lbl': 'Ventricular tachycardia', 'desc': 'label: Ventricular tachycardia\ndefinition : A tachycardia originating in the ventricles characterized by rapid heart rate (over 100 beats per minute) and broad QRS complexes (over 120 ms).\nsynonyms :\n'}


{'id': 'HP_0004757', 'url': 'http://purl.obolibrary.org/obo/HP_0004757', 'lbl': 'Paroxysmal atrial fibrillation', 'desc': 'label: Paroxysmal atrial fibrillation\ndefinition : Episodes of atrial fibrillation that typically last for several hours up to one day and terminate spontaneously.\nsynonyms :Atrial fibrillation, paroxysmal; Intermittent atrial fibrillation; Paroxysmal AF\n'}


{'id': 'HP_0004758', 'url': 'http://purl.obolibrary.org/obo/HP_0004758', 'lbl': 'Effort-induced polymorphic ventricular tachycardia', 'desc': 'label: Effort-induced polymorphic ventricular tachycardia\ndefinition : Polymorphic ventricular arrhythmias of varying morphologythat do not exist under resting conditions but appear only upon physical exercise or catecholamine administration.\nsynonyms :Catecholaminergic polymorphic ventricular tachycardia; Exercise-induced polymorphic ventricular tachycardia\n'}


{'id': 'HP_0004759', 'url': 'http://purl.obolibrary.org/obo/HP_0004759', 'lbl': 'obsolete Nodular calcific aortic valve disease', 'desc': 'label: obsolete Nodular calcific aortic valve disease\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004760', 'url': 'http://purl.obolibrary.org/obo/HP_0004760', 'lbl': 'obsolete Congenital septal defect', 'desc': 'label: obsolete Congenital septal defect\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004761', 'url': 'http://purl.obolibrary.org/obo/HP_0004761', 'lbl': 'Post-angioplasty coronary artery restenosis', 'desc': 'label: Post-angioplasty coronary artery restenosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004762', 'url': 'http://purl.obolibrary.org/obo/HP_0004762', 'lbl': 'Hypoplasia of right ventricle', 'desc': 'label: Hypoplasia of right ventricle\ndefinition : Underdevelopment or reduced size of the heart right ventricle, often due to a reduced number of cells.\nsynonyms :Heart right ventricle hypoplasia; Small right heart chamber; Underdeveloped right heart chamber\n'}


{'id': 'HP_0004763', 'url': 'http://purl.obolibrary.org/obo/HP_0004763', 'lbl': 'Paroxysmal supraventricular tachycardia', 'desc': 'label: Paroxysmal supraventricular tachycardia\ndefinition : An episodic form of supraventricular tachycardia with abrupt onset and termination.\nsynonyms :Episodic rapid heart beat; Episodic supraventricular tachycardia\n'}


{'id': 'HP_0004764', 'url': 'http://purl.obolibrary.org/obo/HP_0004764', 'lbl': 'Myxomatous mitral valve degeneration', 'desc': 'label: Myxomatous mitral valve degeneration\ndefinition : Myxomatous mitral valve is defined as the presence of excess leaflet tissue and leaflet thickening greater than 5 mm, resulting in a prolapse greater than 2 mm into the left atrium on parasternal long axis view.\nsynonyms :\n'}


{'id': 'HP_0004768', 'url': 'http://purl.obolibrary.org/obo/HP_0004768', 'lbl': 'Sparse anterior scalp hair', 'desc': 'label: Sparse anterior scalp hair\ndefinition : Decreased number of head hairs per unit area on the anterior region of the scalp.\nsynonyms :Sparse scalp hair at front of head; Thin scalp hair at front of head\n'}


{'id': 'HP_0004771', 'url': 'http://purl.obolibrary.org/obo/HP_0004771', 'lbl': 'Premature graying of body hair', 'desc': 'label: Premature graying of body hair\ndefinition : \nsynonyms :Premature graying of body hair; Premature greying of body hair\n'}


{'id': 'HP_0004779', 'url': 'http://purl.obolibrary.org/obo/HP_0004779', 'lbl': 'Brittle scalp hair', 'desc': 'label: Brittle scalp hair\ndefinition : Fragile, easily breakable scalp hair.\nsynonyms :Brittle scalp hair\n'}


{'id': 'HP_0004780', 'url': 'http://purl.obolibrary.org/obo/HP_0004780', 'lbl': 'Elbow hypertrichosis', 'desc': 'label: Elbow hypertrichosis\ndefinition : Excessive, increased hair growth located in the elbow region.\nsynonyms :Hairy elbow; Hairy elbow syndrome; Hypertrichosis cubiti; Pilosity of elbow\n'}


{'id': 'HP_0004782', 'url': 'http://purl.obolibrary.org/obo/HP_0004782', 'lbl': 'obsolete Hypotrichosis of the scalp', 'desc': 'label: obsolete Hypotrichosis of the scalp\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004783', 'url': 'http://purl.obolibrary.org/obo/HP_0004783', 'lbl': 'Duodenal polyposis', 'desc': 'label: Duodenal polyposis\ndefinition : Presence of multiple polyps in the duodenum.\nsynonyms :Multiple duodenal polyps\n'}


{'id': 'HP_0004784', 'url': 'http://purl.obolibrary.org/obo/HP_0004784', 'lbl': 'Juvenile gastrointestinal polyposis', 'desc': 'label: Juvenile gastrointestinal polyposis\ndefinition : The presence of multiple juvenile polyps in the stomach and intestine. The term juvenile polyps refer to a special histopathology and not the age of onset as the polyp might be diagnosed at all ages. The juvenile polyp has a spherical appearance and is microscopically characterized by overgrowth of an oedematous lamina propria with inflammatory cells and cystic glands. Juvenile polyps are a specific type of hamartomatous polyps.\nsynonyms :Juvenile GI polyposis\n'}


{'id': 'HP_0004785', 'url': 'http://purl.obolibrary.org/obo/HP_0004785', 'lbl': 'Malrotation of colon', 'desc': 'label: Malrotation of colon\ndefinition : An anatomical anomaly that results from an abnormal rotation of the gut as it returns to the abdominal cavity during embryogenesis.\nsynonyms :\n'}


{'id': 'HP_0004786', 'url': 'http://purl.obolibrary.org/obo/HP_0004786', 'lbl': 'Jejunal diverticula', 'desc': 'label: Jejunal diverticula\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004787', 'url': 'http://purl.obolibrary.org/obo/HP_0004787', 'lbl': 'Fulminant hepatitis', 'desc': 'label: Fulminant hepatitis\ndefinition : Acute hepatitis complicated by acute liver failure with hepatic encephalopathy occurring less than 8 weeks after the onset of jaundice.\nsynonyms :\n'}


{'id': 'HP_0004788', 'url': 'http://purl.obolibrary.org/obo/HP_0004788', 'lbl': 'Intestinal lymphedema', 'desc': 'label: Intestinal lymphedema\ndefinition : Fluid retention and edema in the intestine caused by a compromised lymphatic system.\nsynonyms :\n'}


{'id': 'HP_0004789', 'url': 'http://purl.obolibrary.org/obo/HP_0004789', 'lbl': 'Lactose intolerance', 'desc': 'label: Lactose intolerance\ndefinition : An inability to digest lactose.\nsynonyms :Lactose intolerance; Milk intolerance\n'}


{'id': 'HP_0004790', 'url': 'http://purl.obolibrary.org/obo/HP_0004790', 'lbl': 'Hypoplasia of the small intestine', 'desc': 'label: Hypoplasia of the small intestine\ndefinition : Underdevelopment of the small intestine.\nsynonyms :Underdeveloped small intestine\n'}


{'id': 'HP_0004791', 'url': 'http://purl.obolibrary.org/obo/HP_0004791', 'lbl': 'Esophageal ulceration', 'desc': 'label: Esophageal ulceration\ndefinition : Defect in the epithelium of the esophagus, essentially an open sore in the lining of the esophagus.\nsynonyms :Esophagus ulcer; Oesophagus ulcer; Oesophagus ulceration\n'}


{'id': 'HP_0004792', 'url': 'http://purl.obolibrary.org/obo/HP_0004792', 'lbl': 'Rectoperineal fistula', 'desc': 'label: Rectoperineal fistula\ndefinition : The presence of a fistula between the perineum and the rectum.\nsynonyms :\n'}


{'id': 'HP_0004794', 'url': 'http://purl.obolibrary.org/obo/HP_0004794', 'lbl': 'Malrotation of small bowel', 'desc': 'label: Malrotation of small bowel\ndefinition : A deviation from the normal rotation of the midgut during embryologic development with mislocalization of the small bowel.\nsynonyms :Malrotation of the small intestine\n'}


{'id': 'HP_0004795', 'url': 'http://purl.obolibrary.org/obo/HP_0004795', 'lbl': 'Hamartomatous stomach polyps', 'desc': 'label: Hamartomatous stomach polyps\ndefinition : Polyp-like protrusions which are histologically hamartomas located in the stomach.\nsynonyms :\n'}


{'id': 'HP_0004796', 'url': 'http://purl.obolibrary.org/obo/HP_0004796', 'lbl': 'Gastrointestinal obstruction', 'desc': 'label: Gastrointestinal obstruction\ndefinition : \nsynonyms :GI obstruction; Gastrointestinal obstruction; Obstruction in digestive tract\n'}


{'id': 'HP_0004797', 'url': 'http://purl.obolibrary.org/obo/HP_0004797', 'lbl': 'Multiple small bowel atresias', 'desc': 'label: Multiple small bowel atresias\ndefinition : The presence of multiple areas of atresia affecting the small intestine.\nsynonyms :\n'}


{'id': 'HP_0004798', 'url': 'http://purl.obolibrary.org/obo/HP_0004798', 'lbl': 'Recurrent infection of the gastrointestinal tract', 'desc': 'label: Recurrent infection of the gastrointestinal tract\ndefinition : Recurrent infection of the gastrointestinal tract.\nsynonyms :Recurrent gastrointestinal infections; Recurrent infection of the GI tract; Recurrent infection of the gastrointestinal tract; Gastrointestinal infections; Gastrointestinal infections, recurrent\n'}


{'id': 'HP_0004799', 'url': 'http://purl.obolibrary.org/obo/HP_0004799', 'lbl': 'Jejunoileal diverticula', 'desc': 'label: Jejunoileal diverticula\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004800', 'url': 'http://purl.obolibrary.org/obo/HP_0004800', 'lbl': 'Duodenal diverticula', 'desc': 'label: Duodenal diverticula\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004802', 'url': 'http://purl.obolibrary.org/obo/HP_0004802', 'lbl': 'Episodic hemolytic anemia', 'desc': 'label: Episodic hemolytic anemia\ndefinition : A form of hemolytic anemia that occurs in repeated episodes.\nsynonyms :Episodic hemolysis; Episodic hemolytic anaemia\n'}


{'id': 'HP_0004804', 'url': 'http://purl.obolibrary.org/obo/HP_0004804', 'lbl': 'Congenital hemolytic anemia', 'desc': 'label: Congenital hemolytic anemia\ndefinition : A form of hemolytic anemia with congenital onset.\nsynonyms :Congenital haemolytic anaemia; Congenital haemolytic anemia; Congenital hemolytic anaemia; Neonatal hemolytic anaemia; Neonatal hemolytic anemia\n'}


{'id': 'HP_0004808', 'url': 'http://purl.obolibrary.org/obo/HP_0004808', 'lbl': 'Acute myeloid leukemia', 'desc': 'label: Acute myeloid leukemia\ndefinition : A form of leukemia characterized by overproduction of an early myeloid cell.\nsynonyms :AML; Acute myeloblastic leukaemia; Acute myeloblastic leukemia; Acute myelocytic leukaemia; Acute myelocytic leukemia; Acute myelogenous leukaemia; Acute myelogenous leukemia; Acute myeloid leukaemia\n'}


{'id': 'HP_0004809', 'url': 'http://purl.obolibrary.org/obo/HP_0004809', 'lbl': 'Neonatal alloimmune thrombocytopenia', 'desc': 'label: Neonatal alloimmune thrombocytopenia\ndefinition : Low platelet count associated with maternal platelet-specific alloantibodies.\nsynonyms :\n'}


{'id': 'HP_0004810', 'url': 'http://purl.obolibrary.org/obo/HP_0004810', 'lbl': 'Congenital hypoplastic anemia', 'desc': 'label: Congenital hypoplastic anemia\ndefinition : A type of hypoplastic anemia with congenital onset.\nsynonyms :Congenital dyserythropoietic anaemia; Congenital dyserythropoietic anemia; Congenital hypoplastic anaemia\n'}


{'id': 'HP_0004812', 'url': 'http://purl.obolibrary.org/obo/HP_0004812', 'lbl': 'B Acute Lymphoblastic Leukemia', 'desc': 'label: B Acute Lymphoblastic Leukemia\ndefinition : A type of ALL characterized by elevated levels of B-cell lymphoblasts in the bone marrow and the blood.\nsynonyms :B Acute Lymphoblastic Leukaemia; Pre-B-cell acute lymphoblastic leukaemia; Pre-B-cell acute lymphoblastic leukemia\n'}


{'id': 'HP_0004813', 'url': 'http://purl.obolibrary.org/obo/HP_0004813', 'lbl': 'Post-transfusion thrombocytopenia', 'desc': 'label: Post-transfusion thrombocytopenia\ndefinition : Sudden onset of thrombocytopenia (reduced platelet count) within 5-10 days of the transfusion of blood products. The clinical presentation is post-transfusion purpura (PTP), wigth severe thrmbocytopenia, epistaxis, and hemorrhages.\nsynonyms :Post-transfusion purpura\n'}


{'id': 'HP_0004814', 'url': 'http://purl.obolibrary.org/obo/HP_0004814', 'lbl': 'Fava bean-induced hemolytic anemia', 'desc': 'label: Fava bean-induced hemolytic anemia\ndefinition : A kind of hemolytic anemia that is induced by the ingestion of fava beans.\nsynonyms :Fava bean-induced hemolytic anaemia; Hemolytic anaemia following ingestion of fava beans; Hemolytic anemia following ingestion of fava beans\n'}


{'id': 'HP_0004817', 'url': 'http://purl.obolibrary.org/obo/HP_0004817', 'lbl': 'Drug-sensitive hemolytic anemia', 'desc': 'label: Drug-sensitive hemolytic anemia\ndefinition : A form of hemolytic anemia that is triggered by ingestion of certain drugs.\nsynonyms :Drug-sensitive hemolytic anaemia\n'}


{'id': 'HP_0004818', 'url': 'http://purl.obolibrary.org/obo/HP_0004818', 'lbl': 'Paroxysmal nocturnal hemoglobinuria', 'desc': 'label: Paroxysmal nocturnal hemoglobinuria\ndefinition : \nsynonyms :Paroxysmal nocturnal haemoglobinuria\n'}


{'id': 'HP_0004819', 'url': 'http://purl.obolibrary.org/obo/HP_0004819', 'lbl': 'Normocytic hypoplastic anemia', 'desc': 'label: Normocytic hypoplastic anemia\ndefinition : A type of hypoplastic anemia in which the erythrocytes have a normal cell volume (the mean corpuscular volume is within normal limits).\nsynonyms :Normocytic hypoplastic anaemia\n'}


{'id': 'HP_0004820', 'url': 'http://purl.obolibrary.org/obo/HP_0004820', 'lbl': 'Acute myelomonocytic leukemia', 'desc': 'label: Acute myelomonocytic leukemia\ndefinition : An acute leukemia characterized by the proliferation of both neutrophil and monocyte precursors.\nsynonyms :Acute myelomonocytic leukaemia\n'}


{'id': 'HP_0004821', 'url': 'http://purl.obolibrary.org/obo/HP_0004821', 'lbl': 'Hypersegmentation of neutrophil nuclei', 'desc': 'label: Hypersegmentation of neutrophil nuclei\ndefinition : An excessive division of the lobes of the nucleus of a neutrophil.\nsynonyms :Hypermature neutrophils; Hypersegmentation of neutrophil nuclei in peripheral blood\n'}


{'id': 'HP_0004822', 'url': 'http://purl.obolibrary.org/obo/HP_0004822', 'lbl': 'Atypical elliptocytosis', 'desc': 'label: Atypical elliptocytosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004823', 'url': 'http://purl.obolibrary.org/obo/HP_0004823', 'lbl': 'Anisopoikilocytosis', 'desc': 'label: Anisopoikilocytosis\ndefinition : A type of poikilocytosis characterized by the presence in the blood of erythrocytes of varying sizes and abnormal shapes.\nsynonyms :\n'}


{'id': 'HP_0004825', 'url': 'http://purl.obolibrary.org/obo/HP_0004825', 'lbl': 'Increased hemoglobin oxygen affinity', 'desc': 'label: Increased hemoglobin oxygen affinity\ndefinition : An abnormal increase in the binding affinity of hemoglobin for oxygen.\nsynonyms :Increased Hb O2 affinity; Increased Hb oxygen affinity; Increased haemoglobin O2 affinity; Increased haemoglobin oxygen affinity; Increased hemoglobin O2 affinity\n'}


{'id': 'HP_0004826', 'url': 'http://purl.obolibrary.org/obo/HP_0004826', 'lbl': 'Folate-unresponsive megaloblastic anemia', 'desc': 'label: Folate-unresponsive megaloblastic anemia\ndefinition : A type of megaloblastic anemia that does not improve upon administration of folate. Since vitamin B12 acts by promoting recycling of folate, administration of vitamin B12 also does not improve this type of anemia.\nsynonyms :Folate-unresponsive megaloblastic anaemia\n'}


{'id': 'HP_0004828', 'url': 'http://purl.obolibrary.org/obo/HP_0004828', 'lbl': 'Refractory anemia with ringed sideroblasts', 'desc': 'label: Refractory anemia with ringed sideroblasts\ndefinition : A type of myelodysplastic syndrome characterized by less than 5% myeloblasts in the bone marrow, but with 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.\nsynonyms :Myelodysplasia with sideroblastosis; Refractory anaemia with ringed sideroblasts\n'}


{'id': 'HP_0004831', 'url': 'http://purl.obolibrary.org/obo/HP_0004831', 'lbl': 'Recurrent thromboembolism', 'desc': 'label: Recurrent thromboembolism\ndefinition : Repeated episodes of obstruction of blood flow due to an embolus, i.e., blood clot that has traveled from its point of origin within the blood stream.\nsynonyms :Recurrent thromboembolic disease\n'}


{'id': 'HP_0004835', 'url': 'http://purl.obolibrary.org/obo/HP_0004835', 'lbl': 'Microspherocytosis', 'desc': 'label: Microspherocytosis\ndefinition : The presence of erythrocytes that are sphere-shaped and reduced in size.\nsynonyms :\n'}


{'id': 'HP_0004836', 'url': 'http://purl.obolibrary.org/obo/HP_0004836', 'lbl': 'Acute promyelocytic leukemia', 'desc': 'label: Acute promyelocytic leukemia\ndefinition : A type of acute myeloid leukemia in which abnormal promyelocytes predominate.\nsynonyms :Acute promyelocytic leukaemia\n'}


{'id': 'HP_0004839', 'url': 'http://purl.obolibrary.org/obo/HP_0004839', 'lbl': 'Pyropoikilocytosis', 'desc': 'label: Pyropoikilocytosis\ndefinition : A form of severe hemolytic anemia characterized by erythrocyte morphology reminiscent of that seen in patients after a thermal burn.\nsynonyms :hereditary pyropoikilocytosis\n'}


{'id': 'HP_0004840', 'url': 'http://purl.obolibrary.org/obo/HP_0004840', 'lbl': 'Hypochromic microcytic anemia', 'desc': 'label: Hypochromic microcytic anemia\ndefinition : A type of anemia characterized by an abnormally low concentration of hemoglobin in the erythrocytes and lower than normal size of the erythrocytes.\nsynonyms :Hypochromic microcytic anaemia; Hypochromic, microcytic anaemia; Hypochromic, microcytic anemia\n'}


{'id': 'HP_0004841', 'url': 'http://purl.obolibrary.org/obo/HP_0004841', 'lbl': 'Reduced factor XII activity', 'desc': 'label: Reduced factor XII activity\ndefinition : Decreased activity of coagulation factor XII. Factor XII (fXII) is part of the intrinsic coagulation pathway and binds to exposed collagen at site of vessel wall injury, activated by high-MW kininogen and kallikrein, thereby initiating the coagulation cascade.\nsynonyms :Factor XII deficiency; Hageman factor deficiency\n'}


{'id': 'HP_0004844', 'url': 'http://purl.obolibrary.org/obo/HP_0004844', 'lbl': 'Coombs-positive hemolytic anemia', 'desc': 'label: Coombs-positive hemolytic anemia\ndefinition : A type of hemolytic anemia in which the Coombs test is positive.\nsynonyms :Coombs-positive hemolytic anaemia; Direct Coombs positive\n'}


{'id': 'HP_0004845', 'url': 'http://purl.obolibrary.org/obo/HP_0004845', 'lbl': 'Acute monocytic leukemia', 'desc': 'label: Acute monocytic leukemia\ndefinition : The accumulation of transformed primitive hematopoietic blast cells, which lose their ability of normal differentiation and proliferation.\nsynonyms :AML-M5; AMoL; Acute monoblastic leukaemia; Acute monoblastic leukemia; Acute monocytic leukaemia\n'}


{'id': 'HP_0004846', 'url': 'http://purl.obolibrary.org/obo/HP_0004846', 'lbl': 'Prolonged bleeding after surgery', 'desc': 'label: Prolonged bleeding after surgery\ndefinition : Bleeding that persists longer than the normal time following a surgical procedure.\nsynonyms :Excessive bleeding during surgery; Prolonged bleeding after surgery; Protracted bleeding after surgery\n'}


{'id': 'HP_0004848', 'url': 'http://purl.obolibrary.org/obo/HP_0004848', 'lbl': 'Ph-positive acute lymphoblastic leukemia', 'desc': 'label: Ph-positive acute lymphoblastic leukemia\ndefinition : A subset of acute lymphoblastic leukemia that results from a reciprocal translocation between the ABL-1 oncogene and a breakpoint cluster region (BCR), resulting in a fusion gene, BCR-ABL, that encodes an oncogenic protein with constitutively active tyrosine kinase activity.\nsynonyms :Ph-positive acute lymphoblastic leukaemia; Philadelphia-positive acute lymphoblastic leukaemia; Philadelphia-positive acute lymphoblastic leukemia\n'}


{'id': 'HP_0004850', 'url': 'http://purl.obolibrary.org/obo/HP_0004850', 'lbl': 'Recurrent deep vein thrombosis', 'desc': 'label: Recurrent deep vein thrombosis\ndefinition : Repeated episodes of the formation of a blot clot in a deep vein.\nsynonyms :Recurrent deep vein blood clot; Recurrent venous thrombosis\n'}


{'id': 'HP_0004851', 'url': 'http://purl.obolibrary.org/obo/HP_0004851', 'lbl': 'Folate-responsive megaloblastic anemia', 'desc': 'label: Folate-responsive megaloblastic anemia\ndefinition : A type of megaloblastic anemia (i.e., anemia characterized by the presence of erythroblasts that are larger than normal) that improves upon the administration of folate.\nsynonyms :Folate-responsive megaloblastic anaemia\n'}


{'id': 'HP_0004852', 'url': 'http://purl.obolibrary.org/obo/HP_0004852', 'lbl': 'Reduced leukocyte alkaline phosphatase', 'desc': 'label: Reduced leukocyte alkaline phosphatase\ndefinition : Decreased alkaline phosphatase measured within leukocytes.\nsynonyms :Low leukocyte alkaline phosphatase; Reduced leukocyte ALP\n'}


{'id': 'HP_0004854', 'url': 'http://purl.obolibrary.org/obo/HP_0004854', 'lbl': 'Intermittent thrombocytopenia', 'desc': 'label: Intermittent thrombocytopenia\ndefinition : Reduced platelet count that occurs sporadically, i.e., it comes and goes.\nsynonyms :\n'}


{'id': 'HP_0004855', 'url': 'http://purl.obolibrary.org/obo/HP_0004855', 'lbl': 'Reduced protein S activity', 'desc': 'label: Reduced protein S activity\ndefinition : An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C.\nsynonyms :Protein S deficiency\n'}


{'id': 'HP_0004856', 'url': 'http://purl.obolibrary.org/obo/HP_0004856', 'lbl': 'Normochromic microcytic anemia', 'desc': 'label: Normochromic microcytic anemia\ndefinition : A type of anemia characterized by an normal concentration of hemoglobin in the erythrocytes and lower than normal size of the erythrocytes.\nsynonyms :Normochromic microcytic anaemia\n'}


{'id': 'HP_0004857', 'url': 'http://purl.obolibrary.org/obo/HP_0004857', 'lbl': 'Hyperchromic macrocytic anemia', 'desc': 'label: Hyperchromic macrocytic anemia\ndefinition : A type of anemia characterized by abnormally large erythrocytes with abnormally high amounts of haemoglobin.\nsynonyms :Hyperchromic macrocytic anaemia\n'}


{'id': 'HP_0004859', 'url': 'http://purl.obolibrary.org/obo/HP_0004859', 'lbl': 'Amegakaryocytic thrombocytopenia', 'desc': 'label: Amegakaryocytic thrombocytopenia\ndefinition : Thrombocytopenia related to lack of or severe reduction in the count of megakaryocytes.\nsynonyms :\n'}


{'id': 'HP_0004860', 'url': 'http://purl.obolibrary.org/obo/HP_0004860', 'lbl': 'Thiamine-responsive megaloblastic anemia', 'desc': 'label: Thiamine-responsive megaloblastic anemia\ndefinition : A type of megaloblastic anemia (i.e., anemia characterized by the presence of erythroblasts that are larger than normal) that improves upon the administration of thiamine.\nsynonyms :Thiamine-responsive megaloblastic anaemia\n'}


{'id': 'HP_0004861', 'url': 'http://purl.obolibrary.org/obo/HP_0004861', 'lbl': 'Refractory macrocytic anemia', 'desc': 'label: Refractory macrocytic anemia\ndefinition : \nsynonyms :Refractory macrocytic anaemia\n'}


{'id': 'HP_0004863', 'url': 'http://purl.obolibrary.org/obo/HP_0004863', 'lbl': 'Compensated hemolytic anemia', 'desc': 'label: Compensated hemolytic anemia\ndefinition : \nsynonyms :Compensated hemolytic anaemia\n'}


{'id': 'HP_0004864', 'url': 'http://purl.obolibrary.org/obo/HP_0004864', 'lbl': 'Refractory sideroblastic anemia', 'desc': 'label: Refractory sideroblastic anemia\ndefinition : A type of sideroblastic anemia that is not responsive to treatment.\nsynonyms :Refractory sideroblastic anaemia\n'}


{'id': 'HP_0004866', 'url': 'http://purl.obolibrary.org/obo/HP_0004866', 'lbl': 'Impaired ADP-induced platelet aggregation', 'desc': 'label: Impaired ADP-induced platelet aggregation\ndefinition : Abnormal platelet response to ADP as manifested by reduced or lacking aggregation of platelets upon addition of ADP.\nsynonyms :\n'}


{'id': 'HP_0004870', 'url': 'http://purl.obolibrary.org/obo/HP_0004870', 'lbl': 'Chronic hemolytic anemia', 'desc': 'label: Chronic hemolytic anemia\ndefinition : An chronic form of hemolytic anemia.\nsynonyms :Chronic hemolytic anaemia; hemolytic anemia, chronic\n'}


{'id': 'HP_0004871', 'url': 'http://purl.obolibrary.org/obo/HP_0004871', 'lbl': 'Perineal fistula', 'desc': 'label: Perineal fistula\ndefinition : The presence of a fistula between the bowel and the perineum.\nsynonyms :\n'}


{'id': 'HP_0004872', 'url': 'http://purl.obolibrary.org/obo/HP_0004872', 'lbl': 'Incisional hernia', 'desc': 'label: Incisional hernia\ndefinition : An abdominal hernia that occurs at a site of weakness in the abdominal wall resulting from an incompletely-healed surgical wound.\nsynonyms :Recurrent abdominal hernia\n'}


{'id': 'HP_0004875', 'url': 'http://purl.obolibrary.org/obo/HP_0004875', 'lbl': 'Neonatal inspiratory stridor', 'desc': 'label: Neonatal inspiratory stridor\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004876', 'url': 'http://purl.obolibrary.org/obo/HP_0004876', 'lbl': 'Spontaneous neonatal pneumothorax', 'desc': 'label: Spontaneous neonatal pneumothorax\ndefinition : Pneumothorax occurring neonatally without traumatic injury to the chest or lung.\nsynonyms :Neonatal pneumothorax\n'}


{'id': 'HP_0004878', 'url': 'http://purl.obolibrary.org/obo/HP_0004878', 'lbl': 'Intercostal muscle weakness', 'desc': 'label: Intercostal muscle weakness\ndefinition : Lack of strength of the intercostal muscles, i.e., of the muscle groups running along the ribs that create and move the chest wall.\nsynonyms :Muscle weakness between ribs; Dependence on diaphragmatic breathing\n'}


{'id': 'HP_0004879', 'url': 'http://purl.obolibrary.org/obo/HP_0004879', 'lbl': 'Intermittent hyperventilation', 'desc': 'label: Intermittent hyperventilation\ndefinition : Episodic hyperventilation.\nsynonyms :Episodic hyperventilation; Intermittent overbreathing\n'}


{'id': 'HP_0004880', 'url': 'http://purl.obolibrary.org/obo/HP_0004880', 'lbl': 'Respiratory infections in early life', 'desc': 'label: Respiratory infections in early life\ndefinition : Increased susceptibility to respiratory infections in early life, as manifested by recurrent episodes of respiratory infections.\nsynonyms :\n'}


{'id': 'HP_0004881', 'url': 'http://purl.obolibrary.org/obo/HP_0004881', 'lbl': 'Episodic hypoventilation', 'desc': 'label: Episodic hypoventilation\ndefinition : \nsynonyms :Episodic slow breathing; Episodic under breathing\n'}


{'id': 'HP_0004885', 'url': 'http://purl.obolibrary.org/obo/HP_0004885', 'lbl': 'Episodic respiratory distress', 'desc': 'label: Episodic respiratory distress\ndefinition : \nsynonyms :Episodic difficulty breathing; respiratory distress, episodic\n'}


{'id': 'HP_0004886', 'url': 'http://purl.obolibrary.org/obo/HP_0004886', 'lbl': 'Congenital laryngeal stridor', 'desc': 'label: Congenital laryngeal stridor\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004887', 'url': 'http://purl.obolibrary.org/obo/HP_0004887', 'lbl': 'Respiratory failure requiring assisted ventilation', 'desc': 'label: Respiratory failure requiring assisted ventilation\ndefinition : A state of respiratory distress that requires a life saving intervention in the form of gaining airway access and instituting positive pressure ventilation.\nsynonyms :Respiratory distress necessitating mechanical ventilation; Respiratory distress requiring endotracheal intubation; Respiratory distress requiring mechanical ventilation\n'}


{'id': 'HP_0004889', 'url': 'http://purl.obolibrary.org/obo/HP_0004889', 'lbl': 'Intermittent episodes of respiratory insufficiency due to muscle weakness', 'desc': 'label: Intermittent episodes of respiratory insufficiency due to muscle weakness\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004890', 'url': 'http://purl.obolibrary.org/obo/HP_0004890', 'lbl': 'Elevated pulmonary artery pressure', 'desc': 'label: Elevated pulmonary artery pressure\ndefinition : An abnormally elevated blood pressure in the circulation of the pulmonary artery.\nsynonyms :Elevated lung artery pressure; increased pulmonary artery pressure\n'}


{'id': 'HP_0004891', 'url': 'http://purl.obolibrary.org/obo/HP_0004891', 'lbl': 'Recurrent infections due to aspiration', 'desc': 'label: Recurrent infections due to aspiration\ndefinition : Increased susceptibility to infections due to aspiration, as manifested by recurrent episodes of infections due to aspiration.\nsynonyms :\n'}


{'id': 'HP_0004894', 'url': 'http://purl.obolibrary.org/obo/HP_0004894', 'lbl': 'Laryngotracheal stenosis', 'desc': 'label: Laryngotracheal stenosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004897', 'url': 'http://purl.obolibrary.org/obo/HP_0004897', 'lbl': 'Stress/infection-induced lactic acidosis', 'desc': 'label: Stress/infection-induced lactic acidosis\ndefinition : A form of lactic acidemia that occurs in relation to stress or infection.\nsynonyms :Metabolic crises during febrile infections\n'}


{'id': 'HP_0004898', 'url': 'http://purl.obolibrary.org/obo/HP_0004898', 'lbl': 'Persistent lactic acidosis', 'desc': 'label: Persistent lactic acidosis\ndefinition : A continuous form of lactic acidemia.\nsynonyms :\n'}


{'id': 'HP_0004900', 'url': 'http://purl.obolibrary.org/obo/HP_0004900', 'lbl': 'Severe lactic acidosis', 'desc': 'label: Severe lactic acidosis\ndefinition : A severe form of lactic acidemia.\nsynonyms :\n'}


{'id': 'HP_0004901', 'url': 'http://purl.obolibrary.org/obo/HP_0004901', 'lbl': 'Exercise-induced lactic acidemia', 'desc': 'label: Exercise-induced lactic acidemia\ndefinition : A form of lactic acidemia that occurs following exercise or exertion.\nsynonyms :Exercise-induced lactic acidosis\n'}


{'id': 'HP_0004902', 'url': 'http://purl.obolibrary.org/obo/HP_0004902', 'lbl': 'Congenital lactic acidosis', 'desc': 'label: Congenital lactic acidosis\ndefinition : A form of lactic acidemia with congenital onset.\nsynonyms :\n'}


{'id': 'HP_0004904', 'url': 'http://purl.obolibrary.org/obo/HP_0004904', 'lbl': 'Maturity-onset diabetes of the young', 'desc': 'label: Maturity-onset diabetes of the young\ndefinition : The term Maturity-onset diabetes of the young (MODY) was initially used for patients diagnosed with fasting hyperglycemia that could be treated without insulin for more than two years, where the initial diagnosis was made at a young age (under 25 years). Thus, MODY combines characteristics of type 1 diabetes (young age at diagnosis) and type 2 diabetes (less insulin dependence than type 1 diabetes). The term MODY is now most often used to refer to a group of monogenic diseases with these characteristics. Here, the term is used to describe hyperglycemia diagnosed at a young age with no or minor insulin dependency, no evidence of insulin resistence, and lack of evidence of autoimmune destruction of the beta cells.\nsynonyms :Maturity onset diabetes of the young; MODY\n'}


{'id': 'HP_0004905', 'url': 'http://purl.obolibrary.org/obo/HP_0004905', 'lbl': 'Low levels of vitamin A', 'desc': 'label: Low levels of vitamin A\ndefinition : A reduced concentration of vitamin A.\nsynonyms :Vitamin A deficiency\n'}


{'id': 'HP_0004906', 'url': 'http://purl.obolibrary.org/obo/HP_0004906', 'lbl': 'Hypernatremic dehydration', 'desc': 'label: Hypernatremic dehydration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004909', 'url': 'http://purl.obolibrary.org/obo/HP_0004909', 'lbl': 'Hypokalemic hypochloremic metabolic alkalosis', 'desc': 'label: Hypokalemic hypochloremic metabolic alkalosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004910', 'url': 'http://purl.obolibrary.org/obo/HP_0004910', 'lbl': 'Bicarbonate-wasting renal tubular acidosis', 'desc': 'label: Bicarbonate-wasting renal tubular acidosis\ndefinition : \nsynonyms :HCO3-wasting renal tubular acidosis; Renal bicarbonate wasting\n'}


{'id': 'HP_0004911', 'url': 'http://purl.obolibrary.org/obo/HP_0004911', 'lbl': 'Episodic metabolic acidosis', 'desc': 'label: Episodic metabolic acidosis\ndefinition : Repeated transient episodes of metabolic acidosis, that is, of the buildup of acid or depletion of base due to accumulation of metabolic acids.\nsynonyms :Recurrent episodes of acidosis\n'}


{'id': 'HP_0004912', 'url': 'http://purl.obolibrary.org/obo/HP_0004912', 'lbl': 'Hypophosphatemic rickets', 'desc': 'label: Hypophosphatemic rickets\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004913', 'url': 'http://purl.obolibrary.org/obo/HP_0004913', 'lbl': 'Intermittent lactic acidemia', 'desc': 'label: Intermittent lactic acidemia\ndefinition : An intermittent (discontinuous) form of lactic acidemia.\nsynonyms :\n'}


{'id': 'HP_0004914', 'url': 'http://purl.obolibrary.org/obo/HP_0004914', 'lbl': 'Recurrent infantile hypoglycemia', 'desc': 'label: Recurrent infantile hypoglycemia\ndefinition : Recurrent episodes of decreased concentration of glucose in the blood occurring during the infantile period.\nsynonyms :Episodic infantile hypoglycemia; Recurrent low blood sugar in infant\n'}


{'id': 'HP_0004915', 'url': 'http://purl.obolibrary.org/obo/HP_0004915', 'lbl': 'Impairment of galactose metabolism', 'desc': 'label: Impairment of galactose metabolism\ndefinition : An impairment of galactose metabolism.\nsynonyms :Impaired galactose metabolism\n'}


{'id': 'HP_0004916', 'url': 'http://purl.obolibrary.org/obo/HP_0004916', 'lbl': 'Generalized distal tubular acidosis', 'desc': 'label: Generalized distal tubular acidosis\ndefinition : \nsynonyms :Generalised distal tubular acidosis\n'}


{'id': 'HP_0004918', 'url': 'http://purl.obolibrary.org/obo/HP_0004918', 'lbl': 'Hyperchloremic metabolic acidosis', 'desc': 'label: Hyperchloremic metabolic acidosis\ndefinition : A form of metabolic acidosis with increased serum chloride levels.\nsynonyms :Non-gap acidosis\n'}


{'id': 'HP_0004919', 'url': 'http://purl.obolibrary.org/obo/HP_0004919', 'lbl': 'Galactose intolerance', 'desc': 'label: Galactose intolerance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004920', 'url': 'http://purl.obolibrary.org/obo/HP_0004920', 'lbl': 'Phenylpyruvic acidemia', 'desc': 'label: Phenylpyruvic acidemia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004921', 'url': 'http://purl.obolibrary.org/obo/HP_0004921', 'lbl': 'Abnormal magnesium concentration', 'desc': 'label: Abnormal magnesium concentration\ndefinition : An abnormality of magnesium ion homeostasis.\nsynonyms :Abnormal Mg concentration; Abnormality of magnesium homeostasis; Abnormal magnesium metabolism\n'}


{'id': 'HP_0004922', 'url': 'http://purl.obolibrary.org/obo/HP_0004922', 'lbl': 'Atypical hyperphenylalaninemia', 'desc': 'label: Atypical hyperphenylalaninemia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004923', 'url': 'http://purl.obolibrary.org/obo/HP_0004923', 'lbl': 'Hyperphenylalaninemia', 'desc': 'label: Hyperphenylalaninemia\ndefinition : An increased concentration of L-phenylalanine in the blood.\nsynonyms :\n'}


{'id': 'HP_0004924', 'url': 'http://purl.obolibrary.org/obo/HP_0004924', 'lbl': 'Abnormal oral glucose tolerance', 'desc': 'label: Abnormal oral glucose tolerance\ndefinition : An abnormal resistance to glucose, i.e., a reduction in the ability to maintain glucose levels in the blood stream within normal limits following oral administration of glucose.\nsynonyms :Abnormal glucose oral tolerance test\n'}


{'id': 'HP_0004925', 'url': 'http://purl.obolibrary.org/obo/HP_0004925', 'lbl': 'Chronic lactic acidosis', 'desc': 'label: Chronic lactic acidosis\ndefinition : A chronic form of lactic acidemia.\nsynonyms :\n'}


{'id': 'HP_0004926', 'url': 'http://purl.obolibrary.org/obo/HP_0004926', 'lbl': 'Orthostatic hypotension due to autonomic dysfunction', 'desc': 'label: Orthostatic hypotension due to autonomic dysfunction\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004927', 'url': 'http://purl.obolibrary.org/obo/HP_0004927', 'lbl': 'Pulmonary artery dilatation', 'desc': 'label: Pulmonary artery dilatation\ndefinition : An abnormal widening of the diameter of the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0004928', 'url': 'http://purl.obolibrary.org/obo/HP_0004928', 'lbl': 'obsolete Peripheral arterial stenosis', 'desc': 'label: obsolete Peripheral arterial stenosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004929', 'url': 'http://purl.obolibrary.org/obo/HP_0004929', 'lbl': 'obsolete Coronary atherosclerosis', 'desc': 'label: obsolete Coronary atherosclerosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004930', 'url': 'http://purl.obolibrary.org/obo/HP_0004930', 'lbl': 'Abnormality of the pulmonary vasculature', 'desc': 'label: Abnormality of the pulmonary vasculature\ndefinition : \nsynonyms :Abnormality of the lung blood vessels\n'}


{'id': 'HP_0004931', 'url': 'http://purl.obolibrary.org/obo/HP_0004931', 'lbl': 'Arteriosclerosis of small cerebral arteries', 'desc': 'label: Arteriosclerosis of small cerebral arteries\ndefinition : Arteriosclerosis (increased thickness, increased stiffness, loss of elasticity) of the small arteries of the brain.\nsynonyms :Hardened artery wall in small cerebral arteries\n'}


{'id': 'HP_0004933', 'url': 'http://purl.obolibrary.org/obo/HP_0004933', 'lbl': 'Ascending aortic dissection', 'desc': 'label: Ascending aortic dissection\ndefinition : A separation of the layers within the wall of the ascending aorta. Tears in the intimal layer result in the propagation of dissection (proximally or distally) secondary to blood entering the intima-media space.\nsynonyms :Type A aortic dissection\n'}


{'id': 'HP_0004934', 'url': 'http://purl.obolibrary.org/obo/HP_0004934', 'lbl': 'Vascular calcification', 'desc': 'label: Vascular calcification\ndefinition : Abnormal calcification of the vasculature.\nsynonyms :\n'}


{'id': 'HP_0004935', 'url': 'http://purl.obolibrary.org/obo/HP_0004935', 'lbl': 'Pulmonary artery atresia', 'desc': 'label: Pulmonary artery atresia\ndefinition : A congenital anomaly with a narrowing or complete absence of the opening between the right ventricle and the pulmonary artery.\nsynonyms :Pulmonary atresia\n'}


{'id': 'HP_0004936', 'url': 'http://purl.obolibrary.org/obo/HP_0004936', 'lbl': 'Venous thrombosis', 'desc': 'label: Venous thrombosis\ndefinition : Formation of a blood clot (thrombus) inside a vein, causing the obstruction of blood flow.\nsynonyms :Blood clot in vein\n'}


{'id': 'HP_0004937', 'url': 'http://purl.obolibrary.org/obo/HP_0004937', 'lbl': 'Pulmonary artery aneurysm', 'desc': 'label: Pulmonary artery aneurysm\ndefinition : An aneurysm (severe localized balloon-like outward bulging) in the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0004938', 'url': 'http://purl.obolibrary.org/obo/HP_0004938', 'lbl': 'Tortuous cerebral arteries', 'desc': 'label: Tortuous cerebral arteries\ndefinition : Excessive bending, twisting, and winding of a cerebral artery.\nsynonyms :Twisted cerebral arteries\n'}


{'id': 'HP_0004940', 'url': 'http://purl.obolibrary.org/obo/HP_0004940', 'lbl': 'Generalized arterial calcification', 'desc': 'label: Generalized arterial calcification\ndefinition : Calcification, that is, pathological deposition of calcium salts, affecting arteries distributed throughout the body.\nsynonyms :Generalised arterial calcification\n'}


{'id': 'HP_0004941', 'url': 'http://purl.obolibrary.org/obo/HP_0004941', 'lbl': 'Extrahepatic portal hypertension', 'desc': 'label: Extrahepatic portal hypertension\ndefinition : Increased pressure in the pre-hepatic portal vein.\nsynonyms :\n'}


{'id': 'HP_0004942', 'url': 'http://purl.obolibrary.org/obo/HP_0004942', 'lbl': 'Aortic aneurysm', 'desc': 'label: Aortic aneurysm\ndefinition : Aortic dilatation refers to a dimension that is greater than the 95th percentile for the normal person age, sex and body size. In contrast, an aneurysm is defined as a localized dilation of the aorta that is more than 150 percent of predicted (ratio of observed to expected diameter 1.5 or more). Aneurysm should be distinguished from ectasia, which represents a diffuse dilation of the aorta less than 50 percent of normal aorta diameter.\nsynonyms :Aortic dilatation; Bulge in wall of large artery that carries blood away from heart\n'}


{'id': 'HP_0004943', 'url': 'http://purl.obolibrary.org/obo/HP_0004943', 'lbl': 'Accelerated atherosclerosis', 'desc': 'label: Accelerated atherosclerosis\ndefinition : Atherosclerosis which occurs in a person with certain risk factors (e.g., SLE, diabetes, smoking, hypertension, hypercholesterolaemia, family history of early heart disease) at an earlier age than would occur in another person without those risk factors.\nsynonyms :Accelerated plaque build-up in arteries\n'}


{'id': 'HP_0004944', 'url': 'http://purl.obolibrary.org/obo/HP_0004944', 'lbl': 'Dilatation of the cerebral artery', 'desc': 'label: Dilatation of the cerebral artery\ndefinition : The presence of a localized dilatation or ballooning of a cerebral artery.\nsynonyms :Brain aneurysm; Intracranial aneurysm; Cerebral aneurysm; Cerebral artery aneurysm\n'}


{'id': 'HP_0004945', 'url': 'http://purl.obolibrary.org/obo/HP_0004945', 'lbl': 'Extracranial internal carotid artery dissection', 'desc': 'label: Extracranial internal carotid artery dissection\ndefinition : A separation (dissection) of the layers of the extracranial portion of the internal carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0004947', 'url': 'http://purl.obolibrary.org/obo/HP_0004947', 'lbl': 'Arteriovenous fistula', 'desc': 'label: Arteriovenous fistula\ndefinition : An abnormal connection between an artery and vein.\nsynonyms :Arteriovenous fistulas\n'}


{'id': 'HP_0004948', 'url': 'http://purl.obolibrary.org/obo/HP_0004948', 'lbl': 'Vascular tortuosity', 'desc': 'label: Vascular tortuosity\ndefinition : Abnormal twisting of arteries or veins.\nsynonyms :Twisted blood vessels\n'}


{'id': 'HP_0004950', 'url': 'http://purl.obolibrary.org/obo/HP_0004950', 'lbl': 'Peripheral arterial stenosis', 'desc': 'label: Peripheral arterial stenosis\ndefinition : Narrowing of peripheral arteries with reduction of blood flow to the limbs. This feature may be quantified as an ankle-brachial index of less than 0.9, and may be manifested clinically as claudication.\nsynonyms :Peripheral artery disease; Arterial disease of legs; Occlusive arterial disease; Occlusive vascular disease; Peripheral artery occlusive disease; Peripheral vascular disease\n'}


{'id': 'HP_0004952', 'url': 'http://purl.obolibrary.org/obo/HP_0004952', 'lbl': 'Pulmonary arteriovenous fistulas', 'desc': 'label: Pulmonary arteriovenous fistulas\ndefinition : A rare vascular anomaly with a direct communication between pulmonary artery and pulmonary vein without an intervening capillary bed.\nsynonyms :\n'}


{'id': 'HP_0004953', 'url': 'http://purl.obolibrary.org/obo/HP_0004953', 'lbl': 'obsolete Dilatation of abdominal aorta', 'desc': 'label: obsolete Dilatation of abdominal aorta\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004954', 'url': 'http://purl.obolibrary.org/obo/HP_0004954', 'lbl': 'obsolete Dilatation of the descending aorta', 'desc': 'label: obsolete Dilatation of the descending aorta\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004955', 'url': 'http://purl.obolibrary.org/obo/HP_0004955', 'lbl': 'Generalized arterial tortuosity', 'desc': 'label: Generalized arterial tortuosity\ndefinition : Abnormal tortuous (i.e., twisted) form of arteries affecting most or all arteries.\nsynonyms :Generalised arterial tortuosity; Generalised twisted arteries; Generalized twisted arteries; Arterial tortuosity, general; Arterial tortuosity, generalised; Arterial tortuosity, generalized\n'}


{'id': 'HP_0004959', 'url': 'http://purl.obolibrary.org/obo/HP_0004959', 'lbl': 'Descending thoracic aorta aneurysm', 'desc': 'label: Descending thoracic aorta aneurysm\ndefinition : An abnormal localized widening (dilatation) of the descending thoracic aorta.\nsynonyms :Dilatation of the descending thoracic aorta\n'}


{'id': 'HP_0004960', 'url': 'http://purl.obolibrary.org/obo/HP_0004960', 'lbl': 'Absent pulmonary artery', 'desc': 'label: Absent pulmonary artery\ndefinition : A congenital defect with aplasia (absence) of one of the right or left pulmonary artery.\nsynonyms :Absent lung artery; Missing pulmonary artery\n'}


{'id': 'HP_0004961', 'url': 'http://purl.obolibrary.org/obo/HP_0004961', 'lbl': 'Pulmonary artery sling', 'desc': 'label: Pulmonary artery sling\ndefinition : An anomalous origin of the left pulmonary artery, such that it arises from the posterior aspect of the right pulmonary artery and passes between the trachea and esophagus to reach the left hilum.\nsynonyms :\n'}


{'id': 'HP_0004962', 'url': 'http://purl.obolibrary.org/obo/HP_0004962', 'lbl': 'Thoracic aorta calcification', 'desc': 'label: Thoracic aorta calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the thoracic aorta.\nsynonyms :\n'}


{'id': 'HP_0004963', 'url': 'http://purl.obolibrary.org/obo/HP_0004963', 'lbl': 'Calcification of the aorta', 'desc': 'label: Calcification of the aorta\ndefinition : Calcification, that is, pathological deposition of calcium salts in the aorta.\nsynonyms :\n'}


{'id': 'HP_0004964', 'url': 'http://purl.obolibrary.org/obo/HP_0004964', 'lbl': 'Pulmonary arterial medial hypertrophy', 'desc': 'label: Pulmonary arterial medial hypertrophy\ndefinition : Increase in mass of the tunica media of the arteries in the pulmonary circulation.\nsynonyms :Hypertrophy of the pulmonary artery wall\n'}


{'id': 'HP_0004966', 'url': 'http://purl.obolibrary.org/obo/HP_0004966', 'lbl': 'Medial calcification of large arteries', 'desc': 'label: Medial calcification of large arteries\ndefinition : Calcification, that is, pathological deposition of calcium salts in the tunica media of large (conduit) arteries.\nsynonyms :\n'}


{'id': 'HP_0004968', 'url': 'http://purl.obolibrary.org/obo/HP_0004968', 'lbl': 'Recurrent cerebral hemorrhage', 'desc': 'label: Recurrent cerebral hemorrhage\ndefinition : Recurrent bleeding into the parenchyma of the brain.\nsynonyms :Recurrent cerebral haemorrhage; Recurrent hemorrhagic stroke\n'}


{'id': 'HP_0004969', 'url': 'http://purl.obolibrary.org/obo/HP_0004969', 'lbl': 'Peripheral pulmonary artery stenosis', 'desc': 'label: Peripheral pulmonary artery stenosis\ndefinition : Stenosis of a peripheral branch of the pulmonary artery.\nsynonyms :Narrowing of peripheral lung artery; Peripheral pulmonic stenosis; peripheral pulmonary stenosis\n'}


{'id': 'HP_0004970', 'url': 'http://purl.obolibrary.org/obo/HP_0004970', 'lbl': 'Ascending tubular aorta aneurysm', 'desc': 'label: Ascending tubular aorta aneurysm\ndefinition : An abnormal localized widening (dilatation) of the tubular part of the ascending aorta.\nsynonyms :Ascending aorta dilation; Aneurysm of the ascending tubular aorta; Ascending aortic aneurysm; Ascending aortic dilation; Bulging of wall of large artery located above heart; Dilatation of ascending aorta\n'}


{'id': 'HP_0004971', 'url': 'http://purl.obolibrary.org/obo/HP_0004971', 'lbl': 'Pulmonary artery hypoplasia', 'desc': 'label: Pulmonary artery hypoplasia\ndefinition : Underdevelopment of the pulmonary artery.\nsynonyms :Underdeveloped lung artery; Underdeveloped pulmonary artery\n'}


{'id': 'HP_0004972', 'url': 'http://purl.obolibrary.org/obo/HP_0004972', 'lbl': 'Elevated mean arterial pressure', 'desc': 'label: Elevated mean arterial pressure\ndefinition : An abnormal increase in the average blood pressure in an individual during a single cardiac cycle.\nsynonyms :\n'}


{'id': 'HP_0004974', 'url': 'http://purl.obolibrary.org/obo/HP_0004974', 'lbl': 'Coarctation of abdominal aorta', 'desc': 'label: Coarctation of abdominal aorta\ndefinition : Coarctation of the aorta is a narrowing or constriction of a segment of the abdominal aorta.\nsynonyms :\n'}


{'id': 'HP_0004975', 'url': 'http://purl.obolibrary.org/obo/HP_0004975', 'lbl': 'Erlenmeyer flask deformity of the femurs', 'desc': 'label: Erlenmeyer flask deformity of the femurs\ndefinition : Flaring of distal femur.\nsynonyms :Erlenmeyer flask deformity of distal femur; Erlenmeyer flask femora; Erlenmeyer flask shaped thighbone\n'}


{'id': 'HP_0004976', 'url': 'http://purl.obolibrary.org/obo/HP_0004976', 'lbl': 'Knee dislocation', 'desc': 'label: Knee dislocation\ndefinition : \nsynonyms :Dislocations of the knees; Knee dislocations\n'}


{'id': 'HP_0004977', 'url': 'http://purl.obolibrary.org/obo/HP_0004977', 'lbl': 'Bilateral radial aplasia', 'desc': 'label: Bilateral radial aplasia\ndefinition : Missing radius bone on both sides associated with congenital failure of development.\nsynonyms :Bilateral absence of radius\n'}


{'id': 'HP_0004979', 'url': 'http://purl.obolibrary.org/obo/HP_0004979', 'lbl': 'Metaphyseal sclerosis', 'desc': 'label: Metaphyseal sclerosis\ndefinition : Abnormally increased density of metaphyseal bone.\nsynonyms :Increased bone density in wide portion of long bone; Sclerotic metaphyses\n'}


{'id': 'HP_0004980', 'url': 'http://purl.obolibrary.org/obo/HP_0004980', 'lbl': 'Metaphyseal rarefaction', 'desc': 'label: Metaphyseal rarefaction\ndefinition : Reduction in density of metaphyseal bony tissue.\nsynonyms :Rarefaction of the metaphyses\n'}


{'id': 'HP_0004981', 'url': 'http://purl.obolibrary.org/obo/HP_0004981', 'lbl': 'Prominent styloid process of ulna', 'desc': 'label: Prominent styloid process of ulna\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004986', 'url': 'http://purl.obolibrary.org/obo/HP_0004986', 'lbl': 'obsolete Rudimentary to absent fibulae', 'desc': 'label: obsolete Rudimentary to absent fibulae\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004987', 'url': 'http://purl.obolibrary.org/obo/HP_0004987', 'lbl': 'Mesomelic leg shortening', 'desc': 'label: Mesomelic leg shortening\ndefinition : Shortening of the middle parts of the leg in relation to the upper and terminal segments.\nsynonyms :Mesomelia of the lower limbs; Mesomelic lower limb shortening\n'}


{'id': 'HP_0004990', 'url': 'http://purl.obolibrary.org/obo/HP_0004990', 'lbl': 'Epiphyseal streaking', 'desc': 'label: Epiphyseal streaking\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004991', 'url': 'http://purl.obolibrary.org/obo/HP_0004991', 'lbl': 'Rhizomelic arm shortening', 'desc': 'label: Rhizomelic arm shortening\ndefinition : Disproportionate shortening of the proximal segment of the arm (i.e. the humerus).\nsynonyms :\n'}


{'id': 'HP_0004993', 'url': 'http://purl.obolibrary.org/obo/HP_0004993', 'lbl': 'Slender long bones with narrow diaphyses', 'desc': 'label: Slender long bones with narrow diaphyses\ndefinition : Reduced diameter of a long bone with a more pronounced reduction of the diameter of the diaphysis of the long bones.\nsynonyms :Slender long bones with narrow shaft\n'}


{'id': 'HP_0004997', 'url': 'http://purl.obolibrary.org/obo/HP_0004997', 'lbl': 'Multicentric ossification of proximal humeral epiphyses', 'desc': 'label: Multicentric ossification of proximal humeral epiphyses\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005001', 'url': 'http://purl.obolibrary.org/obo/HP_0005001', 'lbl': 'Recurrent patellar dislocation', 'desc': 'label: Recurrent patellar dislocation\ndefinition : Patellar dislocation occurring repeated times.\nsynonyms :Recurrent dislocation of patellas\n'}


{'id': 'HP_0005003', 'url': 'http://purl.obolibrary.org/obo/HP_0005003', 'lbl': 'Aplasia/Hypoplasia of the capital femoral epiphysis', 'desc': 'label: Aplasia/Hypoplasia of the capital femoral epiphysis\ndefinition : Absence or underdevelopment of the proximal epiphysis of the femur.\nsynonyms :Absent/small end part of innermost thighbone; Absent/underdeveloped end part of innermost thighbone\n'}


{'id': 'HP_0005004', 'url': 'http://purl.obolibrary.org/obo/HP_0005004', 'lbl': 'Flattened proximal radial epiphyses', 'desc': 'label: Flattened proximal radial epiphyses\ndefinition : An abnormally flat form of the proximal epiphysis of the radius.\nsynonyms :\n'}


{'id': 'HP_0005005', 'url': 'http://purl.obolibrary.org/obo/HP_0005005', 'lbl': 'Femoral bowing present at birth, straightening with time', 'desc': 'label: Femoral bowing present at birth, straightening with time\ndefinition : Congenital onset bending or abnormal curvature of the femur that normalizes with age.\nsynonyms :Bowing of thighbone at birth, straightening with time\n'}


{'id': 'HP_0005008', 'url': 'http://purl.obolibrary.org/obo/HP_0005008', 'lbl': 'Large joint dislocations', 'desc': 'label: Large joint dislocations\ndefinition : \nsynonyms :Large joint dislocations\n'}


{'id': 'HP_0005009', 'url': 'http://purl.obolibrary.org/obo/HP_0005009', 'lbl': 'Dumbbell-shaped humerus', 'desc': 'label: Dumbbell-shaped humerus\ndefinition : The humerus is shortened and displays flaring (widening) of the metaphyses.\nsynonyms :Dumbbell-shaped long bone in upper arm\n'}


{'id': 'HP_0005010', 'url': 'http://purl.obolibrary.org/obo/HP_0005010', 'lbl': 'Osteomyelitis leading to amputation due to slow healing fractures', 'desc': 'label: Osteomyelitis leading to amputation due to slow healing fractures\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005011', 'url': 'http://purl.obolibrary.org/obo/HP_0005011', 'lbl': 'Mesomelic arm shortening', 'desc': 'label: Mesomelic arm shortening\ndefinition : Shortening of the middle parts of the arm in relation to the upper and terminal segments.\nsynonyms :Mesomelia of the upper limbs; Upper limb brachymesomelia\n'}


{'id': 'HP_0005013', 'url': 'http://purl.obolibrary.org/obo/HP_0005013', 'lbl': 'Dysplastic distal radial epiphyses', 'desc': 'label: Dysplastic distal radial epiphyses\ndefinition : Abnormally developed (dysplastic) distal epiphysis of the radius.\nsynonyms :\n'}


{'id': 'HP_0005017', 'url': 'http://purl.obolibrary.org/obo/HP_0005017', 'lbl': 'Polyarticular chondrocalcinosis', 'desc': 'label: Polyarticular chondrocalcinosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005019', 'url': 'http://purl.obolibrary.org/obo/HP_0005019', 'lbl': 'Diaphyseal thickening', 'desc': 'label: Diaphyseal thickening\ndefinition : \nsynonyms :Thickening of shaft or central part of long bones\n'}


{'id': 'HP_0005021', 'url': 'http://purl.obolibrary.org/obo/HP_0005021', 'lbl': 'Bilateral elbow dislocations', 'desc': 'label: Bilateral elbow dislocations\ndefinition : \nsynonyms :Dislocated elbows on both sides\n'}


{'id': 'HP_0005025', 'url': 'http://purl.obolibrary.org/obo/HP_0005025', 'lbl': 'Hypoplastic distal humeri', 'desc': 'label: Hypoplastic distal humeri\ndefinition : Underdevelopment of the distal portion of the humerus.\nsynonyms :\n'}


{'id': 'HP_0005026', 'url': 'http://purl.obolibrary.org/obo/HP_0005026', 'lbl': 'Mesomelic/rhizomelic limb shortening', 'desc': 'label: Mesomelic/rhizomelic limb shortening\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005028', 'url': 'http://purl.obolibrary.org/obo/HP_0005028', 'lbl': 'Widened proximal tibial metaphyses', 'desc': 'label: Widened proximal tibial metaphyses\ndefinition : \nsynonyms :Wide innermost wide portion of shankbone bone; Wide innermost wide portion of shinbone bone\n'}


{'id': 'HP_0005033', 'url': 'http://purl.obolibrary.org/obo/HP_0005033', 'lbl': 'Distal ulnar hypoplasia', 'desc': 'label: Distal ulnar hypoplasia\ndefinition : Underdevelopment of the distal portion of the ulna.\nsynonyms :Distal shortening of ulna; Hypoplastic distal ulna\n'}


{'id': 'HP_0005035', 'url': 'http://purl.obolibrary.org/obo/HP_0005035', 'lbl': 'Shortening of all phalanges of the toes', 'desc': 'label: Shortening of all phalanges of the toes\ndefinition : Developmental hypoplasia (shortening) of all phalanges of the foot.\nsynonyms :Short toe bones\n'}


{'id': 'HP_0005036', 'url': 'http://purl.obolibrary.org/obo/HP_0005036', 'lbl': 'Unilateral ulnar hypoplasia', 'desc': 'label: Unilateral ulnar hypoplasia\ndefinition : Underdevelopment of the ulna on only one side.\nsynonyms :\n'}


{'id': 'HP_0005037', 'url': 'http://purl.obolibrary.org/obo/HP_0005037', 'lbl': 'Proximal radio-ulnar synostosis', 'desc': 'label: Proximal radio-ulnar synostosis\ndefinition : An abnormal osseous union (fusion) between the proximal portions of the radius and the ulna.\nsynonyms :\n'}


{'id': 'HP_0005039', 'url': 'http://purl.obolibrary.org/obo/HP_0005039', 'lbl': 'Multiple long-bone exostoses', 'desc': 'label: Multiple long-bone exostoses\ndefinition : Multiple exostoses originating in long bones.\nsynonyms :Multiple exostoses of long tubular bones\n'}


{'id': 'HP_0005041', 'url': 'http://purl.obolibrary.org/obo/HP_0005041', 'lbl': 'Irregular capital femoral epiphysis', 'desc': 'label: Irregular capital femoral epiphysis\ndefinition : Irregular surface of the normally relatively smooth capital femoral epiphysis.\nsynonyms :Irregular end part of innermost thighbone; Irregular proximal femoral epiphyses; Irregular capital femoral epiphyses\n'}


{'id': 'HP_0005042', 'url': 'http://purl.obolibrary.org/obo/HP_0005042', 'lbl': 'Irregular, rachitic-like metaphyses', 'desc': 'label: Irregular, rachitic-like metaphyses\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005043', 'url': 'http://purl.obolibrary.org/obo/HP_0005043', 'lbl': 'Proximal humeral metaphyseal irregularity', 'desc': 'label: Proximal humeral metaphyseal irregularity\ndefinition : Irregularity of the normally smooth surface of the metaphysis at the proximal end of the humerus (at the shoulder).\nsynonyms :Irregular proximal humeral metaphyses\n'}


{'id': 'HP_0005045', 'url': 'http://purl.obolibrary.org/obo/HP_0005045', 'lbl': 'Diaphyseal cortical sclerosis', 'desc': 'label: Diaphyseal cortical sclerosis\ndefinition : An elevation in bone density of the cortex of one or more diaphyses. Sclerosis is normally detected on a radiograph as an area of increased opacity.\nsynonyms :\n'}


{'id': 'HP_0005048', 'url': 'http://purl.obolibrary.org/obo/HP_0005048', 'lbl': 'Synostosis of carpal bones', 'desc': 'label: Synostosis of carpal bones\ndefinition : \nsynonyms :Fusion of wrist bones\n'}


{'id': 'HP_0005050', 'url': 'http://purl.obolibrary.org/obo/HP_0005050', 'lbl': 'Anterolateral radial head dislocation', 'desc': 'label: Anterolateral radial head dislocation\ndefinition : A dislocation of the head of the radius from its socket in the elbow joint in an anterolateral direction.\nsynonyms :Anterior/lateral radial head dislocation\n'}


{'id': 'HP_0005054', 'url': 'http://purl.obolibrary.org/obo/HP_0005054', 'lbl': 'Metaphyseal spurs', 'desc': 'label: Metaphyseal spurs\ndefinition : Bony outgrowths that extend laterally from the margin of the metaphysis.\nsynonyms :\n'}


{'id': 'HP_0005059', 'url': 'http://purl.obolibrary.org/obo/HP_0005059', 'lbl': 'Arthralgia/arthritis', 'desc': 'label: Arthralgia/arthritis\ndefinition : \nsynonyms :Joint pain/Joint inflammation\n'}


{'id': 'HP_0005060', 'url': 'http://purl.obolibrary.org/obo/HP_0005060', 'lbl': 'Limited elbow flexion/extension', 'desc': 'label: Limited elbow flexion/extension\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005063', 'url': 'http://purl.obolibrary.org/obo/HP_0005063', 'lbl': 'Fragmented, irregular epiphyses', 'desc': 'label: Fragmented, irregular epiphyses\ndefinition : \nsynonyms :Fragmented, irregular end part of bone\n'}


{'id': 'HP_0005066', 'url': 'http://purl.obolibrary.org/obo/HP_0005066', 'lbl': 'Cone-shaped epiphyses fused within their metaphyses', 'desc': 'label: Cone-shaped epiphyses fused within their metaphyses\ndefinition : \nsynonyms :Cone-shaped end part of long bone fused within their wide portion of wide bone\n'}


{'id': 'HP_0005067', 'url': 'http://purl.obolibrary.org/obo/HP_0005067', 'lbl': 'Proximal fibular overgrowth', 'desc': 'label: Proximal fibular overgrowth\ndefinition : Overgrowth of the proximal part of the fibula.\nsynonyms :Overgrowth of innermost part of calf bone\n'}


{'id': 'HP_0005068', 'url': 'http://purl.obolibrary.org/obo/HP_0005068', 'lbl': 'Absent styloid process of ulna', 'desc': 'label: Absent styloid process of ulna\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005069', 'url': 'http://purl.obolibrary.org/obo/HP_0005069', 'lbl': 'Rhizo-meso-acromelic limb shortening', 'desc': 'label: Rhizo-meso-acromelic limb shortening\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005070', 'url': 'http://purl.obolibrary.org/obo/HP_0005070', 'lbl': 'Proximal radial head dislocation', 'desc': 'label: Proximal radial head dislocation\ndefinition : A dislocation of the head of the radius from its socket in the elbow joint in an proximal direction.\nsynonyms :\n'}


{'id': 'HP_0005072', 'url': 'http://purl.obolibrary.org/obo/HP_0005072', 'lbl': 'Hyperextensibility at wrists', 'desc': 'label: Hyperextensibility at wrists\ndefinition : The ability of the wrist joints to move beyond their normal range of motion.\nsynonyms :Increased laxity of wrists; Increased wrist mobility\n'}


{'id': 'HP_0005084', 'url': 'http://purl.obolibrary.org/obo/HP_0005084', 'lbl': 'Anterior radial head dislocation', 'desc': 'label: Anterior radial head dislocation\ndefinition : A dislocation of the head of the radius from its socket in the elbow joint in an anterior direction.\nsynonyms :Anterior dislocation of radial head\n'}


{'id': 'HP_0005085', 'url': 'http://purl.obolibrary.org/obo/HP_0005085', 'lbl': 'Limited knee flexion/extension', 'desc': 'label: Limited knee flexion/extension\ndefinition : A limited ability of the knee joint to perform extension and flexion.\nsynonyms :\n'}


{'id': 'HP_0005086', 'url': 'http://purl.obolibrary.org/obo/HP_0005086', 'lbl': 'Knee osteoarthritis', 'desc': 'label: Knee osteoarthritis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005089', 'url': 'http://purl.obolibrary.org/obo/HP_0005089', 'lbl': 'Abnormal metaphyseal trabeculation', 'desc': 'label: Abnormal metaphyseal trabeculation\ndefinition : An abnormality of the pattern of trabecula (small interconnecting rods of bone) in a metaphyseal region of bone.\nsynonyms :\n'}


{'id': 'HP_0005090', 'url': 'http://purl.obolibrary.org/obo/HP_0005090', 'lbl': 'Lateral femoral bowing', 'desc': 'label: Lateral femoral bowing\ndefinition : A lateral bending or abnormal curvature of the femur.\nsynonyms :\n'}


{'id': 'HP_0005092', 'url': 'http://purl.obolibrary.org/obo/HP_0005092', 'lbl': 'Streaky metaphyseal sclerosis', 'desc': 'label: Streaky metaphyseal sclerosis\ndefinition : The presence of streaks (bands) of abnormally increased density of metaphyseal bone.\nsynonyms :Streak increase in bone density in wide portion of wide bone\n'}


{'id': 'HP_0005093', 'url': 'http://purl.obolibrary.org/obo/HP_0005093', 'lbl': 'Absent proximal radial epiphyses', 'desc': 'label: Absent proximal radial epiphyses\ndefinition : Absence of the proximal radial epiphysis.\nsynonyms :\n'}


{'id': 'HP_0005096', 'url': 'http://purl.obolibrary.org/obo/HP_0005096', 'lbl': 'Distal femoral bowing', 'desc': 'label: Distal femoral bowing\ndefinition : A bending or abnormal curvature of the distal portion of the femur.\nsynonyms :\n'}


{'id': 'HP_0005099', 'url': 'http://purl.obolibrary.org/obo/HP_0005099', 'lbl': 'obsolete Severe hydrops fetalis', 'desc': 'label: obsolete Severe hydrops fetalis\ndefinition : \nsynonyms :Severe hydrops\n'}


{'id': 'HP_0005100', 'url': 'http://purl.obolibrary.org/obo/HP_0005100', 'lbl': 'Premature birth following premature rupture of fetal membranes', 'desc': 'label: Premature birth following premature rupture of fetal membranes\ndefinition : \nsynonyms :Premature birth following premature rupture of foetal membranes\n'}


{'id': 'HP_0005101', 'url': 'http://purl.obolibrary.org/obo/HP_0005101', 'lbl': 'High-frequency hearing impairment', 'desc': 'label: High-frequency hearing impairment\ndefinition : A type of hearing impairment affecting primarily the higher frequencies of sound (3,000 to 6,000 Hz).\nsynonyms :Hearing loss, high-frequency; High frequency hearing loss; High-frequency deafness; Progressive high frequency hearing loss; Progressive high-frequency hearing loss\n'}


{'id': 'HP_0005102', 'url': 'http://purl.obolibrary.org/obo/HP_0005102', 'lbl': 'Cochlear degeneration', 'desc': 'label: Cochlear degeneration\ndefinition : Deterioration or loss of the tissues of the cochlea.\nsynonyms :Progressive cochlear degeneration\n'}


{'id': 'HP_0005103', 'url': 'http://purl.obolibrary.org/obo/HP_0005103', 'lbl': 'Calcification of the auricular cartilage', 'desc': 'label: Calcification of the auricular cartilage\ndefinition : Ossification affecting the external ear cartilage.\nsynonyms :Cartilaginous ossification of pinnae; Ossification of pinnae; Petrified ear; Ear cartilage calcification\n'}


{'id': 'HP_0005104', 'url': 'http://purl.obolibrary.org/obo/HP_0005104', 'lbl': 'Hypoplastic nasal septum', 'desc': 'label: Hypoplastic nasal septum\ndefinition : Underdevelopment of the nasal septum.\nsynonyms :Decreased size of nasal septum; Decreased size of septum of nose; Hypoplasia of septum of nose; Small nasal septum; Small septum of nose\n'}


{'id': 'HP_0005105', 'url': 'http://purl.obolibrary.org/obo/HP_0005105', 'lbl': 'Abnormal nasal morphology', 'desc': 'label: Abnormal nasal morphology\ndefinition : \nsynonyms :Abnormal nose morphology; Abnormal of morphology of nose; Abnormal of nasal shape; Abnormal of shape of nose\n'}


{'id': 'HP_0005106', 'url': 'http://purl.obolibrary.org/obo/HP_0005106', 'lbl': 'Abnormality of the vertebral endplates', 'desc': 'label: Abnormality of the vertebral endplates\ndefinition : Any abnormality of the vertebral end plates, which are the top and bottom portions of the vertebral bodies that interface with the vertebral discs.\nsynonyms :\n'}


{'id': 'HP_0005107', 'url': 'http://purl.obolibrary.org/obo/HP_0005107', 'lbl': 'Abnormal sacrum morphology', 'desc': 'label: Abnormal sacrum morphology\ndefinition : An abnormality of the sacral bone.\nsynonyms :Abnormality of the sacrum\n'}


{'id': 'HP_0005108', 'url': 'http://purl.obolibrary.org/obo/HP_0005108', 'lbl': 'Abnormal intervertebral disk morphology', 'desc': 'label: Abnormal intervertebral disk morphology\ndefinition : Any structural abnormality of the intervertebral disk.\nsynonyms :Abnormality of the intervertebral disc; Abnormality of the intervertebral disk\n'}


{'id': 'HP_0005109', 'url': 'http://purl.obolibrary.org/obo/HP_0005109', 'lbl': 'Abnormality of the Achilles tendon', 'desc': 'label: Abnormality of the Achilles tendon\ndefinition : An abnormality of the Achilles tendon.\nsynonyms :Abnormality of the Achilles tendon; Abnormality of the calcaneal tendon\n'}


{'id': 'HP_0005110', 'url': 'http://purl.obolibrary.org/obo/HP_0005110', 'lbl': 'Atrial fibrillation', 'desc': 'label: Atrial fibrillation\ndefinition : An atrial arrhythmia characterized by disorganized atrial activity without discrete P waves on the surface EKG, but instead by an undulating baseline or more sharply circumscribed atrial deflections of varying amplitude an frequency ranging from 350 to 600 per minute.\nsynonyms :Quivering upper heart chambers resulting in irregular heartbeat\n'}


{'id': 'HP_0005111', 'url': 'http://purl.obolibrary.org/obo/HP_0005111', 'lbl': 'obsolete Dilatation of the ascending aorta', 'desc': 'label: obsolete Dilatation of the ascending aorta\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005112', 'url': 'http://purl.obolibrary.org/obo/HP_0005112', 'lbl': 'Abdominal aortic aneurysm', 'desc': 'label: Abdominal aortic aneurysm\ndefinition : An abnormal localized widening (dilatation) of the abdominal aorta.\nsynonyms :Dilatation of the abdominal aorta\n'}


{'id': 'HP_0005113', 'url': 'http://purl.obolibrary.org/obo/HP_0005113', 'lbl': 'Aortic arch aneurysm', 'desc': 'label: Aortic arch aneurysm\ndefinition : An abnormal localized widening (dilatation) of the aortic arch.\nsynonyms :Aortic arch dilatation; Dilatation of the aortic arch\n'}


{'id': 'HP_0005114', 'url': 'http://purl.obolibrary.org/obo/HP_0005114', 'lbl': 'obsolete Abnormalities of the peripheral arteries', 'desc': 'label: obsolete Abnormalities of the peripheral arteries\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005115', 'url': 'http://purl.obolibrary.org/obo/HP_0005115', 'lbl': 'Supraventricular arrhythmia', 'desc': 'label: Supraventricular arrhythmia\ndefinition : A type of arrhythmia that originates above the ventricles, whereby the electrical impulse propagates down the normal His Purkinje system similar to normal sinus rhythm.\nsynonyms :Supraventricular arrhythmias\n'}


{'id': 'HP_0005116', 'url': 'http://purl.obolibrary.org/obo/HP_0005116', 'lbl': 'Arterial tortuosity', 'desc': 'label: Arterial tortuosity\ndefinition : Abnormal tortuous (i.e., twisted) form of arteries.\nsynonyms :\n'}


{'id': 'HP_0005117', 'url': 'http://purl.obolibrary.org/obo/HP_0005117', 'lbl': 'Elevated diastolic blood pressure', 'desc': 'label: Elevated diastolic blood pressure\ndefinition : Abnormal increase in diastolic blood pressure.\nsynonyms :Elevated diastolic BP\n'}


{'id': 'HP_0005120', 'url': 'http://purl.obolibrary.org/obo/HP_0005120', 'lbl': 'Abnormal cardiac atrium morphology', 'desc': 'label: Abnormal cardiac atrium morphology\ndefinition : Any structural abnormality of a cardiac atrium.\nsynonyms :Abnormality of cardiac atrium morphology; Abnormality of heart atrium\n'}


{'id': 'HP_0005121', 'url': 'http://purl.obolibrary.org/obo/HP_0005121', 'lbl': 'Posterior scalloping of vertebral bodies', 'desc': 'label: Posterior scalloping of vertebral bodies\ndefinition : An excessive concavity of the posterior surface of one or more vertebral bodies.\nsynonyms :Posterior vertebral body scalloping\n'}


{'id': 'HP_0005129', 'url': 'http://purl.obolibrary.org/obo/HP_0005129', 'lbl': 'Congenital hypertrophy of left ventricle', 'desc': 'label: Congenital hypertrophy of left ventricle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005130', 'url': 'http://purl.obolibrary.org/obo/HP_0005130', 'lbl': 'obsolete Restrictive heart failure', 'desc': 'label: obsolete Restrictive heart failure\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0005132', 'url': 'http://purl.obolibrary.org/obo/HP_0005132', 'lbl': 'Pericardial constriction', 'desc': 'label: Pericardial constriction\ndefinition : Compression of the heart caused by rigid, thickened, or fused pericardial membranes.\nsynonyms :\n'}


{'id': 'HP_0005133', 'url': 'http://purl.obolibrary.org/obo/HP_0005133', 'lbl': 'Right ventricular dilatation', 'desc': 'label: Right ventricular dilatation\ndefinition : Enlargement of the chamber of the right ventricle.\nsynonyms :Dilated heart right ventricle\n'}