{'id': 'HP_0000692', 'url': 'http://purl.obolibrary.org/obo/HP_0000692', 'lbl': 'Tooth malposition', 'desc': 'label: Tooth malposition\ndefinition : Abnormal alignment, positioning, or spacing of the teeth, i.e., misaligned teeth.\nsynonyms :Abnormality of position of teeth; Abnormal dental position; Abnormal teeth spacing; Abnormality of alignment of teeth; Abnormality of teeth spacing; Crooked teeth; Malaligned teeth; Malposition of teeth; Malpositioned teeth; Misalignment of teeth; Teeth, malposition\n'}


{'id': 'HP_0000694', 'url': 'http://purl.obolibrary.org/obo/HP_0000694', 'lbl': 'Odontodysplasia', 'desc': 'label: Odontodysplasia\ndefinition : The diagnosis odontodysplasia requires clinical and radiological exams, in which unusually large pulp chambers and large pulp room chambers with thin enamel and dentin are visible. It may affect either a single tooth or several teeth. The term regional odontodysplasia is used if several teeth are affected. It affects the deciduous and permanent dentitions in the maxilla, the mandible or both, although the maxilla is more frequently involved. A type of dental dysplasia occurring in dentinogenesis imperfecta in which the pulp chambers are enlarged and there is a reduced amount of coronal dentin.\nsynonyms :Ghost teeth; Shell teeth; Teeth with dentinal dysplasia; Teeth with thin dentin and large pulp chambers; Teeth with type iii dentinogenesis imperfecta\n'}


{'id': 'HP_0000695', 'url': 'http://purl.obolibrary.org/obo/HP_0000695', 'lbl': 'Natal tooth', 'desc': 'label: Natal tooth\ndefinition : A tooth present at birth or erupting within the first month of life.\nsynonyms :Born with teeth; Natal teeth; Neonatal teeth; Teeth present at birth\n'}


{'id': 'HP_0000696', 'url': 'http://purl.obolibrary.org/obo/HP_0000696', 'lbl': 'Delayed eruption of permanent teeth', 'desc': 'label: Delayed eruption of permanent teeth\ndefinition : Delayed tooth eruption affecting the secondary dentition.\nsynonyms :Delayed eruption of adult teeth; Delayed eruption of permanent teeth; Delayed eruption of secondary dentition; Delayed eruption of secondary teeth; Delayed permanent dentition\n'}


{'id': 'HP_0000698', 'url': 'http://purl.obolibrary.org/obo/HP_0000698', 'lbl': 'Conical tooth', 'desc': 'label: Conical tooth\ndefinition : An abnormal conical form of the teeth, that is, a tooth whose sides converge or taper together incisally.\nsynonyms :Cone shaped tooth; Conoid tooth; Peg shaped teeth; Peg tooth; Peg-shaped teeth; Shark tooth; Conical teeth; Peg shaped tooth; Pointed tooth\n'}


{'id': 'HP_0000699', 'url': 'http://purl.obolibrary.org/obo/HP_0000699', 'lbl': 'Diastema', 'desc': 'label: Diastema\ndefinition : Increased space between two adjacent teeth in the same dental arch.\nsynonyms :Gaps between teeth; Dental diastasis; Dental diastema; Diastasis of the teeth; Diastema of the teeth; Gap between teeth\n'}


{'id': 'HP_0000700', 'url': 'http://purl.obolibrary.org/obo/HP_0000700', 'lbl': 'Periapical bone loss', 'desc': 'label: Periapical bone loss\ndefinition : Radiolucency (reflecting a reduction in the bony substance) around the apex (the tip of the dental root).\nsynonyms :Dark spot around tooth root on x-ray; Periapical lesion; Bone loss around tooth root; Periapical cyst; Periapical granuloma; Periapical radiolucencies; Periapical radiolucency\n'}


{'id': 'HP_0000703', 'url': 'http://purl.obolibrary.org/obo/HP_0000703', 'lbl': 'Dentinogenesis imperfecta', 'desc': 'label: Dentinogenesis imperfecta\ndefinition : Developmental dysplasia of dentin.\nsynonyms :\n'}


{'id': 'HP_0000704', 'url': 'http://purl.obolibrary.org/obo/HP_0000704', 'lbl': 'Periodontitis', 'desc': 'label: Periodontitis\ndefinition : Inflammation of the periodontium.\nsynonyms :Gum disease; Periodontal disease; Pyorrhea\n'}


{'id': 'HP_0000705', 'url': 'http://purl.obolibrary.org/obo/HP_0000705', 'lbl': 'Amelogenesis imperfecta', 'desc': 'label: Amelogenesis imperfecta\ndefinition : A developmental dysplasia of the dental enamel.\nsynonyms :\n'}


{'id': 'HP_0000706', 'url': 'http://purl.obolibrary.org/obo/HP_0000706', 'lbl': 'Eruption failure', 'desc': 'label: Eruption failure\ndefinition : A tooth which does not erupt within the teeth eruption timeline and after the loss of eruption potential.\nsynonyms :Unerupted dentition; Failure of eruption of tooth; Pseudo-anodontia; Pseudoanodontia; Unerupted tooth\n'}


{'id': 'HP_0000707', 'url': 'http://purl.obolibrary.org/obo/HP_0000707', 'lbl': 'Abnormality of the nervous system', 'desc': 'label: Abnormality of the nervous system\ndefinition : An abnormality of the nervous system.\nsynonyms :Brain and/or spinal cord issue; Abnormality of the nervous system; Neurologic abnormalities; Neurological abnormality\n'}


{'id': 'HP_0000708', 'url': 'http://purl.obolibrary.org/obo/HP_0000708', 'lbl': 'Atypical behavior', 'desc': 'label: Atypical behavior\ndefinition : An abnormality of mental functioning including various affective, behavioral, cognitive, and perceptual abnormalities.\nsynonyms :Behavioral abnormality; Behavioral changes; Behavioral disorders; Behavioral disturbances; Behavioral problems; Behavioral symptoms; Behavioral/psychiatric abnormalities; Behavioural abnormality; Behavioural changes; Behavioural disorders; Behavioural disturbances; Behavioural problems; Behavioural symptoms; Behavioural/Psychiatric abnormality; Psychiatric disorders; Psychiatric disturbances\n'}


{'id': 'HP_0000709', 'url': 'http://purl.obolibrary.org/obo/HP_0000709', 'lbl': 'Psychosis', 'desc': 'label: Psychosis\ndefinition : A condition characterized by changes of personality and thought patterns often accompanied by hallucinations and delusional beliefs.\nsynonyms :Psychosis\n'}


{'id': 'HP_0000710', 'url': 'http://purl.obolibrary.org/obo/HP_0000710', 'lbl': 'Hyperorality', 'desc': 'label: Hyperorality\ndefinition : Hyperorality is a condition characterized by an excessive preoccupation with oral sensations and behaviors, such as chewing, sucking, biting, swallowing, and excessive mouthing of objects.\nsynonyms :Hyperoralia; Hyperorality; Mouthing\n'}


{'id': 'HP_0000711', 'url': 'http://purl.obolibrary.org/obo/HP_0000711', 'lbl': 'Restlessness', 'desc': 'label: Restlessness\ndefinition : A state of unease characterized by diffuse motor activity or motion, subject to limited control, nonproductive, or disorganized behavior.\nsynonyms :Fidgetiness; Restiveness\n'}


{'id': 'HP_0000712', 'url': 'http://purl.obolibrary.org/obo/HP_0000712', 'lbl': 'Emotional lability', 'desc': 'label: Emotional lability\ndefinition : Unstable emotional experiences and frequent mood changes; emotions that are easily aroused, intense, and/or out of proportion to events and circumstances.\nsynonyms :Emotional instability; Mood alterations; Mood changes; Mood lability; Mood swings\n'}


{'id': 'HP_0000713', 'url': 'http://purl.obolibrary.org/obo/HP_0000713', 'lbl': 'Agitation', 'desc': 'label: Agitation\ndefinition : A state of exceeding restlessness and excessive motor activity associated with mental distress or a feeling of inner tension.\nsynonyms :\n'}


{'id': 'HP_0000716', 'url': 'http://purl.obolibrary.org/obo/HP_0000716', 'lbl': 'Depression', 'desc': 'label: Depression\ndefinition : Frequent feelings of being down, miserable, and/or hopeless; difficulty recovering from such moods; pessimism about the future; pervasive shame; feeling of inferior self-worth; thoughts of suicide and suicidal behavior.\nsynonyms :Depression; Depressivity; Depressive disorder\n'}


{'id': 'HP_0000717', 'url': 'http://purl.obolibrary.org/obo/HP_0000717', 'lbl': 'Autism', 'desc': 'label: Autism\ndefinition : Autism is a neurodevelopmental disorder characterized by impaired social interaction and communication, and by restricted and repetitive behavior. Autism begins in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual (DSM-IV).\nsynonyms :Autism\n'}


{'id': 'HP_0000718', 'url': 'http://purl.obolibrary.org/obo/HP_0000718', 'lbl': 'Aggressive behavior', 'desc': 'label: Aggressive behavior\ndefinition : Aggressive behavior can denote verbal aggression, physical aggression against objects, physical aggression against people, and may also include aggression towards oneself.\nsynonyms :Aggression; Aggressive behavior; Aggressive behaviour; Aggressiveness; physical aggression\n'}


{'id': 'HP_0000719', 'url': 'http://purl.obolibrary.org/obo/HP_0000719', 'lbl': 'Inappropriate behavior', 'desc': 'label: Inappropriate behavior\ndefinition : \nsynonyms :Inappropriate behavior; Inappropriate behaviour\n'}


{'id': 'HP_0000720', 'url': 'http://purl.obolibrary.org/obo/HP_0000720', 'lbl': 'obsolete Mood swings', 'desc': 'label: obsolete Mood swings\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000721', 'url': 'http://purl.obolibrary.org/obo/HP_0000721', 'lbl': 'Lack of spontaneous play', 'desc': 'label: Lack of spontaneous play\ndefinition : \nsynonyms :Lack of spontaneous play\n'}


{'id': 'HP_0000722', 'url': 'http://purl.obolibrary.org/obo/HP_0000722', 'lbl': 'Compulsive behaviors', 'desc': "label: Compulsive behaviors\ndefinition : Behavior that consists of repetitive acts that are characterized by the feeling that one 'has to' perform them while one is aware that these acts are not in line with one's overall goal\nsynonyms :OCD; Obsessive compulsive behavior; Obsessive compulsive behaviour; Obsessive compulsive disorder; Obsessive-compulsive behavior; Obsessive-compulsive behaviour; Obsessive-compulsive disorder\n"}


{'id': 'HP_0000723', 'url': 'http://purl.obolibrary.org/obo/HP_0000723', 'lbl': 'Restrictive behavior', 'desc': 'label: Restrictive behavior\ndefinition : Behavior characterized by an abnormal limitation to few interests and activities.\nsynonyms :Restricted behavior; Restricted behaviour; Restrictive behaviour; Restrictive behavior, interests, and activities\n'}


{'id': 'HP_0000725', 'url': 'http://purl.obolibrary.org/obo/HP_0000725', 'lbl': 'Psychotic episodes', 'desc': 'label: Psychotic episodes\ndefinition : \nsynonyms :Psychotic episodes\n'}


{'id': 'HP_0000726', 'url': 'http://purl.obolibrary.org/obo/HP_0000726', 'lbl': 'Dementia', 'desc': 'label: Dementia\ndefinition : A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.\nsynonyms :Dementia; Dementia, progressive; Progressive dementia\n'}


{'id': 'HP_0000727', 'url': 'http://purl.obolibrary.org/obo/HP_0000727', 'lbl': 'Frontal lobe dementia', 'desc': 'label: Frontal lobe dementia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000728', 'url': 'http://purl.obolibrary.org/obo/HP_0000728', 'lbl': 'Impaired ability to form peer relationships', 'desc': 'label: Impaired ability to form peer relationships\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000729', 'url': 'http://purl.obolibrary.org/obo/HP_0000729', 'lbl': 'Autistic behavior', 'desc': 'label: Autistic behavior\ndefinition : Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.\nsynonyms :ASD; Autistic behaviour; Pervasive developmental disorder; Autism spectrum disorder; Autism spectrum disorders; Autistic behaviors; Autistic behaviours\n'}


{'id': 'HP_0000732', 'url': 'http://purl.obolibrary.org/obo/HP_0000732', 'lbl': 'Inflexible adherence to routines or rituals', 'desc': 'label: Inflexible adherence to routines or rituals\ndefinition : A need to strictly adhere to repetitive routines or patterns of behavior; when one becomes upset or distressed when their routines are disrupted or altered.\nsynonyms :\n'}


{'id': 'HP_0000733', 'url': 'http://purl.obolibrary.org/obo/HP_0000733', 'lbl': 'Abnormal repetitive mannerisms', 'desc': "label: Abnormal repetitive mannerisms\ndefinition : Use of the same abnormal action in response to certain triggers or at random. They may be used as a way to regulate one's internal state but must otherwise have no apparent functional purpose.\nsynonyms :Motor stereotypy; Repetitive behaviour Stereotypic behavior; Repetitive movements; Stereotyped; Stereotyped behavior; Stereotyped behaviors; Stereotyped behaviour; Stereotyped behaviours; Stereotypic behaviour; Stereotypic behaviours; Stereotypical motor behavior; Stereotypical motor behaviors; Stereotypical motor behaviours; Stimming; repetitive behavior\n"}


{'id': 'HP_0000734', 'url': 'http://purl.obolibrary.org/obo/HP_0000734', 'lbl': 'Disinhibition', 'desc': 'label: Disinhibition\ndefinition : A lack of restraint manifested in several ways, including disregard for social conventions, impulsivity, and poor risk assessment.\nsynonyms :\n'}


{'id': 'HP_0000735', 'url': 'http://purl.obolibrary.org/obo/HP_0000735', 'lbl': 'Impaired social interactions', 'desc': 'label: Impaired social interactions\ndefinition : Difficulty in social interactions related to an impairment of characteristics such as eye contact, smiling, appropriate facial expressions, and body postures and characterized by difficulty in forming peer relationships and forming friendships.\nsynonyms :Impaired social interaction; Impaired social interactions; Poor social interactions\n'}


{'id': 'HP_0000736', 'url': 'http://purl.obolibrary.org/obo/HP_0000736', 'lbl': 'Short attention span', 'desc': 'label: Short attention span\ndefinition : Reduced attention span characterized by distractibility and impulsivity.\nsynonyms :Easily distracted; Poor attention span; Problem paying attention; Short attention span\n'}


{'id': 'HP_0000737', 'url': 'http://purl.obolibrary.org/obo/HP_0000737', 'lbl': 'Irritability', 'desc': 'label: Irritability\ndefinition : A proneness to anger, i.e., a condition of being easily bothered or annoyed.\nsynonyms :Irritability; Irritable\n'}


{'id': 'HP_0000738', 'url': 'http://purl.obolibrary.org/obo/HP_0000738', 'lbl': 'Hallucinations', 'desc': 'label: Hallucinations\ndefinition : Perceptions in a conscious and awake state in the absence of external stimuli which have qualities of real perception, in that they are vivid, substantial, and located in external objective space.\nsynonyms :Hallucination; Hallucinations; Sensory hallucination\n'}


{'id': 'HP_0000739', 'url': 'http://purl.obolibrary.org/obo/HP_0000739', 'lbl': 'Anxiety', 'desc': 'label: Anxiety\ndefinition : Intense feelings of nervousness, tenseness, or panic, often in reaction to interpersonal stresses; worry about the negative effects of past unpleasant experiences and future negative possibilities; feeling fearful, apprehensive, or threatened by uncertainty; fears of falling apart or losing control.\nsynonyms :Anxiety; Anxiousness; Excessive, persistent worry and fear; Anxiety disease\n'}


{'id': 'HP_0000740', 'url': 'http://purl.obolibrary.org/obo/HP_0000740', 'lbl': 'Episodic paroxysmal anxiety', 'desc': 'label: Episodic paroxysmal anxiety\ndefinition : Recurrent attacks of severe anxiety, whose occurence is not restricted to any particular situation or set of circumstances and is therefore unpredictable.\nsynonyms :\n'}


{'id': 'HP_0000741', 'url': 'http://purl.obolibrary.org/obo/HP_0000741', 'lbl': 'Apathy', 'desc': 'label: Apathy\ndefinition : \nsynonyms :Lack of feeling, emotion, interest\n'}


{'id': 'HP_0000742', 'url': 'http://purl.obolibrary.org/obo/HP_0000742', 'lbl': 'Self-mutilation', 'desc': 'label: Self-mutilation\ndefinition : \nsynonyms :Deliberate self-harm; Self mutilation; Self-mutilation\n'}


{'id': 'HP_0000743', 'url': 'http://purl.obolibrary.org/obo/HP_0000743', 'lbl': 'Frontal release signs', 'desc': 'label: Frontal release signs\ndefinition : Primitive reflexes traditionally held to be a sign of disorders that affect the frontal lobes.\nsynonyms :Frontal release reflexes\n'}


{'id': 'HP_0000744', 'url': 'http://purl.obolibrary.org/obo/HP_0000744', 'lbl': 'Low frustration tolerance', 'desc': 'label: Low frustration tolerance\ndefinition : The feeling of frustration can be defined as an emotional reaction that occurs if a desired goal is not achieved. Frustration intolerance is defined as an age-inappropriate response to frustration characterized by crying or temper tantrums (in children) or aggressive or other undesirable behaviors.\nsynonyms :Intolerance to frustration\n'}


{'id': 'HP_0000745', 'url': 'http://purl.obolibrary.org/obo/HP_0000745', 'lbl': 'Diminished motivation', 'desc': 'label: Diminished motivation\ndefinition : A reduction in goal-directed behavior, that is, motivation, the determinant of behavior and adaptation that allows individuals to get started, be energized to perform a sustained and directed action.\nsynonyms :Diminished motivation; Lack of initiative; Lack of motivation; Lacking in initiative; Lacks initiative\n'}


{'id': 'HP_0000746', 'url': 'http://purl.obolibrary.org/obo/HP_0000746', 'lbl': 'Delusions', 'desc': 'label: Delusions\ndefinition : A false belief that is held despite evidence to the contrary.\nsynonyms :Delusions\n'}


{'id': 'HP_0000748', 'url': 'http://purl.obolibrary.org/obo/HP_0000748', 'lbl': 'Inappropriate laughter', 'desc': 'label: Inappropriate laughter\ndefinition : \nsynonyms :Inappropriate laughter\n'}


{'id': 'HP_0000749', 'url': 'http://purl.obolibrary.org/obo/HP_0000749', 'lbl': 'Paroxysmal bursts of laughter', 'desc': 'label: Paroxysmal bursts of laughter\ndefinition : \nsynonyms :Paroxysmal laughter\n'}


{'id': 'HP_0000750', 'url': 'http://purl.obolibrary.org/obo/HP_0000750', 'lbl': 'Delayed speech and language development', 'desc': 'label: Delayed speech and language development\ndefinition : A degree of language development that is significantly below the norm for a child of a specified age.\nsynonyms :Deficiency of speech development; Delayed language development; Delayed speech; Delayed speech acquisition; Delayed speech and language development; Delayed speech development; Impaired speech and language development; Impaired speech development; Language delay; Language delayed; Language development deficit; Late-onset speech development; Poor language development; Speech and language delay; Speech and language difficulties; Speech delay; Poor speech acquisition; Poor speech development; Speech difficulties\n'}


{'id': 'HP_0000751', 'url': 'http://purl.obolibrary.org/obo/HP_0000751', 'lbl': 'Personality changes', 'desc': 'label: Personality changes\ndefinition : An abnormal shift in patterns of thinking, acting, or feeling.\nsynonyms :Personality change; Personality changes\n'}


{'id': 'HP_0000752', 'url': 'http://purl.obolibrary.org/obo/HP_0000752', 'lbl': 'Hyperactivity', 'desc': 'label: Hyperactivity\ndefinition : Hyperactivity is a state of constantly being unusually or abnormally active, including in situations in which it is not appropriate.\nsynonyms :Hyperactive behavior; Hyperactive behaviour; More active than typical; hyperkinetic disorder\n'}


{'id': 'HP_0000753', 'url': 'http://purl.obolibrary.org/obo/HP_0000753', 'lbl': 'Autism with high cognitive abilities', 'desc': 'label: Autism with high cognitive abilities\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000756', 'url': 'http://purl.obolibrary.org/obo/HP_0000756', 'lbl': 'Agoraphobia', 'desc': 'label: Agoraphobia\ndefinition : A type of anxiety disorder characterized by avoidance of public places, especially where crowds gather.\nsynonyms :Fear of open spaces\n'}


{'id': 'HP_0000757', 'url': 'http://purl.obolibrary.org/obo/HP_0000757', 'lbl': 'Lack of insight', 'desc': 'label: Lack of insight\ndefinition : \nsynonyms :Lack of insight\n'}


{'id': 'HP_0000758', 'url': 'http://purl.obolibrary.org/obo/HP_0000758', 'lbl': 'Abnormal nonverbal communicative behavior', 'desc': "label: Abnormal nonverbal communicative behavior\ndefinition : Abnormalities in eye contact, communicative facial expressions, gesture use, or use of other's body to communicate. These convey a shared meaning within a culture that replace or supplement verbal communication.\nsynonyms :Impaired use of nonverbal behaviors; Impaired use of nonverbal behaviours\n"}


{'id': 'HP_0000759', 'url': 'http://purl.obolibrary.org/obo/HP_0000759', 'lbl': 'Abnormal peripheral nervous system morphology', 'desc': 'label: Abnormal peripheral nervous system morphology\ndefinition : A structural abnormality of the peripheral nervous system, which is composed of the nerves that lead to or branch off from the central nervous system. This includes the cranial nerves (olfactory and optic nerves are technically part of the central nervous system).\nsynonyms :Abnormal peripheral nervous system structure; Peripheral nervous system disease\n'}


{'id': 'HP_0000762', 'url': 'http://purl.obolibrary.org/obo/HP_0000762', 'lbl': 'Decreased nerve conduction velocity', 'desc': 'label: Decreased nerve conduction velocity\ndefinition : A reduction in the speed at which electrical signals propagate along the axon of a neuron.\nsynonyms :Decreased NCV; Decreased nerve conduction velocities; Delayed nerve conduction velocity; Reduced nerve conduction velocities; Slow nerve conduction velocity; Slowed nerve conduction velocities\n'}


{'id': 'HP_0000763', 'url': 'http://purl.obolibrary.org/obo/HP_0000763', 'lbl': 'Sensory neuropathy', 'desc': 'label: Sensory neuropathy\ndefinition : Peripheral neuropathy affecting the sensory nerves.\nsynonyms :Damage to nerves that sense feeling; Peripheral sensory neuropathy\n'}


{'id': 'HP_0000764', 'url': 'http://purl.obolibrary.org/obo/HP_0000764', 'lbl': 'Peripheral axonal degeneration', 'desc': 'label: Peripheral axonal degeneration\ndefinition : Progressive deterioration of peripheral axons.\nsynonyms :\n'}


{'id': 'HP_0000765', 'url': 'http://purl.obolibrary.org/obo/HP_0000765', 'lbl': 'Abnormal thorax morphology', 'desc': 'label: Abnormal thorax morphology\ndefinition : Any abnormality of the thorax (the region of the body formed by the sternum, the thoracic vertebrae and the ribs).\nsynonyms :Abnormality of the chest; Abnormality of the thorax; Structural abnormality of the chest wall\n'}


{'id': 'HP_0000766', 'url': 'http://purl.obolibrary.org/obo/HP_0000766', 'lbl': 'Abnormal sternum morphology', 'desc': 'label: Abnormal sternum morphology\ndefinition : An anomaly of the sternum, also known as the breastbone.\nsynonyms :Abnormality of the sternum; Pectus carinatum or pectus excavatum; Pectus deformities; Pectus deformity; Pectus excavatum or carinatum; Pectus excavatum or pectus carinatum; Pectus excavatum/carinatum; Sternal anomalies\n'}


{'id': 'HP_0000767', 'url': 'http://purl.obolibrary.org/obo/HP_0000767', 'lbl': 'Pectus excavatum', 'desc': 'label: Pectus excavatum\ndefinition : A defect of the chest wall characterized by a depression of the sternum, giving the chest ("pectus") a caved-in ("excavatum") appearance.\nsynonyms :Funnel chest\n'}


{'id': 'HP_0000768', 'url': 'http://purl.obolibrary.org/obo/HP_0000768', 'lbl': 'Pectus carinatum', 'desc': 'label: Pectus carinatum\ndefinition : A deformity of the chest caused by overgrowth of the ribs and characterized by protrusion of the sternum.\nsynonyms :Pigeon chest\n'}


{'id': 'HP_0000769', 'url': 'http://purl.obolibrary.org/obo/HP_0000769', 'lbl': 'Abnormality of the breast', 'desc': 'label: Abnormality of the breast\ndefinition : An abnormality of the breast.\nsynonyms :Abnormality of the breast\n'}


{'id': 'HP_0000771', 'url': 'http://purl.obolibrary.org/obo/HP_0000771', 'lbl': 'Gynecomastia', 'desc': 'label: Gynecomastia\ndefinition : Abnormal development of large mammary glands in males resulting in breast enlargement.\nsynonyms :Enlarged male breast; Gynaecomastia\n'}


{'id': 'HP_0000772', 'url': 'http://purl.obolibrary.org/obo/HP_0000772', 'lbl': 'Abnormal rib morphology', 'desc': 'label: Abnormal rib morphology\ndefinition : An anomaly of the rib.\nsynonyms :Abnormality of the ribs; Rib abnormalities; Rib anomalies\n'}


{'id': 'HP_0000773', 'url': 'http://purl.obolibrary.org/obo/HP_0000773', 'lbl': 'Short ribs', 'desc': 'label: Short ribs\ndefinition : Reduced rib length.\nsynonyms :Hypoplastic ribs; Rib hypoplasia; Short ribs\n'}


{'id': 'HP_0000774', 'url': 'http://purl.obolibrary.org/obo/HP_0000774', 'lbl': 'Narrow chest', 'desc': 'label: Narrow chest\ndefinition : Reduced width of the chest from side to side, associated with a reduced distance from the sternal notch to the tip of the shoulder.\nsynonyms :Low chest circumference; Narrow chest; Narrow shoulders; Narrow thorax; Reduced anterior-posterior chest diameter\n'}


{'id': 'HP_0000775', 'url': 'http://purl.obolibrary.org/obo/HP_0000775', 'lbl': 'Abnormality of the diaphragm', 'desc': 'label: Abnormality of the diaphragm\ndefinition : Any abnormality of the diaphragm, the sheet of skeletal muscle that separates the thoracic cavity from the abdominal cavity.\nsynonyms :Abnormality of the diaphragm; Diaphragm issues; Diaphragmatic defect\n'}


{'id': 'HP_0000776', 'url': 'http://purl.obolibrary.org/obo/HP_0000776', 'lbl': 'Congenital diaphragmatic hernia', 'desc': 'label: Congenital diaphragmatic hernia\ndefinition : The presence of a hernia of the diaphragm present at birth.\nsynonyms :Diaphragmatic hernia\n'}


{'id': 'HP_0000777', 'url': 'http://purl.obolibrary.org/obo/HP_0000777', 'lbl': 'Abnormality of the thymus', 'desc': 'label: Abnormality of the thymus\ndefinition : Abnormality of the thymus, an organ located in the upper anterior portion of the chest cavity just behind the sternum and whose main function is to provide an environment for T lymphocyte maturation.\nsynonyms :Abnormality of the thymus\n'}


{'id': 'HP_0000778', 'url': 'http://purl.obolibrary.org/obo/HP_0000778', 'lbl': 'Hypoplasia of the thymus', 'desc': 'label: Hypoplasia of the thymus\ndefinition : Underdevelopment of the thymus.\nsynonyms :Small thymus; Thymic hypoplasia; Thymus hypoplasia\n'}


{'id': 'HP_0000782', 'url': 'http://purl.obolibrary.org/obo/HP_0000782', 'lbl': 'Abnormal scapula morphology', 'desc': 'label: Abnormal scapula morphology\ndefinition : Any abnormality of the scapula, also known as the shoulder blade.\nsynonyms :Abnormality of the shoulder blade\n'}


{'id': 'HP_0000786', 'url': 'http://purl.obolibrary.org/obo/HP_0000786', 'lbl': 'Primary amenorrhea', 'desc': 'label: Primary amenorrhea\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000787', 'url': 'http://purl.obolibrary.org/obo/HP_0000787', 'lbl': 'Nephrolithiasis', 'desc': 'label: Nephrolithiasis\ndefinition : The presence of calculi (stones) in the kidneys.\nsynonyms :Kidney stones; Renal calculi; Renal stones\n'}


{'id': 'HP_0000789', 'url': 'http://purl.obolibrary.org/obo/HP_0000789', 'lbl': 'Infertility', 'desc': 'label: Infertility\ndefinition : \nsynonyms :Infertility\n'}


{'id': 'HP_0000790', 'url': 'http://purl.obolibrary.org/obo/HP_0000790', 'lbl': 'Hematuria', 'desc': 'label: Hematuria\ndefinition : The presence of blood in the urine. Hematuria may be gross hematuria (visible to the naked eye) or microscopic hematuria (detected by dipstick or microscopic examination of the urine).\nsynonyms :High urine occult blood; Blood in urine\n'}


{'id': 'HP_0000791', 'url': 'http://purl.obolibrary.org/obo/HP_0000791', 'lbl': 'Uric acid nephrolithiasis', 'desc': 'label: Uric acid nephrolithiasis\ndefinition : The presence of uric acid-containing calculi (stones) in the kidneys.\nsynonyms :Uric acid stones; Uric acid urolithiasis\n'}


{'id': 'HP_0000793', 'url': 'http://purl.obolibrary.org/obo/HP_0000793', 'lbl': 'Membranoproliferative glomerulonephritis', 'desc': 'label: Membranoproliferative glomerulonephritis\ndefinition : A type of glomerulonephritis characterized by diffuse mesangial cell proliferation and the thickening of capillary walls due to subendothelial extension of the mesangium. The term membranoproliferative glomerulonephritis is often employed to denote a general pattern of glomerular injury seen in a variety of disease processes that share a common pathogenetic mechanism, rather than to describe a single disease entity\nsynonyms :MPGN; Mesangiocapillary glomerulonephritis\n'}


{'id': 'HP_0000794', 'url': 'http://purl.obolibrary.org/obo/HP_0000794', 'lbl': 'IgA deposition in the glomerulus', 'desc': 'label: IgA deposition in the glomerulus\ndefinition : The presence of immunoglobulin A deposits in the glomerulus.\nsynonyms :IgA nephropathy\n'}


{'id': 'HP_0000795', 'url': 'http://purl.obolibrary.org/obo/HP_0000795', 'lbl': 'Abnormality of the urethra', 'desc': 'label: Abnormality of the urethra\ndefinition : An abnormality of the urethra, i.e., of the tube which connects the urinary bladder to the outside of the body.\nsynonyms :Urethra issue\n'}


{'id': 'HP_0000796', 'url': 'http://purl.obolibrary.org/obo/HP_0000796', 'lbl': 'Urethral obstruction', 'desc': 'label: Urethral obstruction\ndefinition : Obstruction of the flow of urine through the urethra.\nsynonyms :\n'}


{'id': 'HP_0000798', 'url': 'http://purl.obolibrary.org/obo/HP_0000798', 'lbl': 'Oligospermia', 'desc': 'label: Oligospermia\ndefinition : Reduced count of spermatozoa in the semen, defined as a sperm count below 20 million per milliliter semen.\nsynonyms :Low sperm count\n'}


{'id': 'HP_0000799', 'url': 'http://purl.obolibrary.org/obo/HP_0000799', 'lbl': 'Renal steatosis', 'desc': 'label: Renal steatosis\ndefinition : Abnormal fat accumulation in the kidneys.\nsynonyms :Fatty kidney\n'}


{'id': 'HP_0000800', 'url': 'http://purl.obolibrary.org/obo/HP_0000800', 'lbl': 'Cystic renal dysplasia', 'desc': 'label: Cystic renal dysplasia\ndefinition : \nsynonyms :Bilateral cystic dysplasia; Renal cystic dysplasia; Renal dysplasia, cystic\n'}


{'id': 'HP_0000802', 'url': 'http://purl.obolibrary.org/obo/HP_0000802', 'lbl': 'Impotence', 'desc': 'label: Impotence\ndefinition : Inability to develop or maintain an erection of the penis.\nsynonyms :Difficulty getting a full erection; Difficulty getting an erection\n'}


{'id': 'HP_0000803', 'url': 'http://purl.obolibrary.org/obo/HP_0000803', 'lbl': 'Renal cortical cysts', 'desc': 'label: Renal cortical cysts\ndefinition : Cysts of the cortex of the kidney.\nsynonyms :Cortical cysts\n'}


{'id': 'HP_0000804', 'url': 'http://purl.obolibrary.org/obo/HP_0000804', 'lbl': 'Xanthine nephrolithiasis', 'desc': 'label: Xanthine nephrolithiasis\ndefinition : The presence of xanthine-containing calculi (stones) in the kidneys.\nsynonyms :Urinary xanthine stones; Xanthine stones\n'}


{'id': 'HP_0000805', 'url': 'http://purl.obolibrary.org/obo/HP_0000805', 'lbl': 'Enuresis', 'desc': 'label: Enuresis\ndefinition : Lack of the ability to control the urinary bladder leading to involuntary urination at an age where control of the bladder should already be possible.\nsynonyms :\n'}


{'id': 'HP_0000807', 'url': 'http://purl.obolibrary.org/obo/HP_0000807', 'lbl': 'Glandular hypospadias', 'desc': 'label: Glandular hypospadias\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000808', 'url': 'http://purl.obolibrary.org/obo/HP_0000808', 'lbl': 'Penoscrotal hypospadias', 'desc': 'label: Penoscrotal hypospadias\ndefinition : A severe form of hypospadias in which the urethral opening is located at the junction of the penis and scrotum.\nsynonyms :\n'}


{'id': 'HP_0000809', 'url': 'http://purl.obolibrary.org/obo/HP_0000809', 'lbl': 'Urinary tract atresia', 'desc': 'label: Urinary tract atresia\ndefinition : Congenital absence of the normal opening of a structure of the urinary tract.\nsynonyms :\n'}


{'id': 'HP_0000811', 'url': 'http://purl.obolibrary.org/obo/HP_0000811', 'lbl': 'Abnormal external genitalia', 'desc': 'label: Abnormal external genitalia\ndefinition : \nsynonyms :Abnormal external genitalia\n'}


{'id': 'HP_0000812', 'url': 'http://purl.obolibrary.org/obo/HP_0000812', 'lbl': 'Abnormal internal genitalia', 'desc': 'label: Abnormal internal genitalia\ndefinition : An anomaly of the adnexa, uterus, and vagina (in female) or seminal tract and prostate (in male).\nsynonyms :Abnormal internal genitalia\n'}


{'id': 'HP_0000813', 'url': 'http://purl.obolibrary.org/obo/HP_0000813', 'lbl': 'Bicornuate uterus', 'desc': 'label: Bicornuate uterus\ndefinition : The presence of a bicornuate uterus.\nsynonyms :Heart shaped uterus; Heart-shaped uterus; Uterus bicornis\n'}


{'id': 'HP_0000815', 'url': 'http://purl.obolibrary.org/obo/HP_0000815', 'lbl': 'Hypergonadotropic hypogonadism', 'desc': 'label: Hypergonadotropic hypogonadism\ndefinition : Reduced function of the gonads (testes in males or ovaries in females) associated with excess pituitary gonadotropin secretion and resulting in delayed sexual development and growth delay.\nsynonyms :Hypergonadotrophic hypogonadism; Primary hypogonadism\n'}


{'id': 'HP_0000816', 'url': 'http://purl.obolibrary.org/obo/HP_0000816', 'lbl': 'Abnormality of Krebs cycle metabolism', 'desc': 'label: Abnormality of Krebs cycle metabolism\ndefinition : An abnormality of the tricarboxylic acid cycle.\nsynonyms :Abnormality of citric acid cycle; Abnormality of the tricarboxylic cycle\n'}


{'id': 'HP_0000817', 'url': 'http://purl.obolibrary.org/obo/HP_0000817', 'lbl': 'Reduced eye contact', 'desc': 'label: Reduced eye contact\ndefinition : A reduced frequency or duration of eye contact.\nsynonyms :Poor eye contact\n'}


{'id': 'HP_0000818', 'url': 'http://purl.obolibrary.org/obo/HP_0000818', 'lbl': 'Abnormality of the endocrine system', 'desc': 'label: Abnormality of the endocrine system\ndefinition : An abnormality of the endocrine system.\nsynonyms :Endocrine system disease\n'}


{'id': 'HP_0000819', 'url': 'http://purl.obolibrary.org/obo/HP_0000819', 'lbl': 'Diabetes mellitus', 'desc': 'label: Diabetes mellitus\ndefinition : A group of abnormalities characterized by hyperglycemia and glucose intolerance.\nsynonyms :\n'}


{'id': 'HP_0000820', 'url': 'http://purl.obolibrary.org/obo/HP_0000820', 'lbl': 'Abnormality of the thyroid gland', 'desc': 'label: Abnormality of the thyroid gland\ndefinition : An abnormality of the thyroid gland.\nsynonyms :Abnormality of the thyroid gland; Thyroid abnormality; Thyroid disease\n'}


{'id': 'HP_0000821', 'url': 'http://purl.obolibrary.org/obo/HP_0000821', 'lbl': 'Hypothyroidism', 'desc': 'label: Hypothyroidism\ndefinition : Deficiency of thyroid hormone.\nsynonyms :Low T4; Underactive thyroid\n'}


{'id': 'HP_0000822', 'url': 'http://purl.obolibrary.org/obo/HP_0000822', 'lbl': 'Hypertension', 'desc': 'label: Hypertension\ndefinition : The presence of chronic increased pressure in the systemic arterial system.\nsynonyms :Arterial hypertension; Systemic hypertension; High blood pressure\n'}


{'id': 'HP_0000823', 'url': 'http://purl.obolibrary.org/obo/HP_0000823', 'lbl': 'Delayed puberty', 'desc': 'label: Delayed puberty\ndefinition : Passing the age when puberty normally occurs with no physical or hormonal signs of the onset of puberty.\nsynonyms :Delayed pubertal development; Delayed pubertal growth; Delayed puberty; Pubertal delay\n'}


{'id': 'HP_0000824', 'url': 'http://purl.obolibrary.org/obo/HP_0000824', 'lbl': 'Decreased response to growth hormone stimulation test', 'desc': 'label: Decreased response to growth hormone stimulation test\ndefinition : Insufficient responses to growth hormone (GH) provocation tests. GH deficiency is defined as a serum peak GH concentration less than 10 ng/mL on provocation with a combination of at least two separate stimulation tests.\nsynonyms :Growth hormone deficiency; Somatotropin deficiency\n'}


{'id': 'HP_0000825', 'url': 'http://purl.obolibrary.org/obo/HP_0000825', 'lbl': 'Hyperinsulinemic hypoglycemia', 'desc': 'label: Hyperinsulinemic hypoglycemia\ndefinition : An increased concentration of insulin combined with a decreased concentration of glucose in the blood.\nsynonyms :Hyperinsulinaemic hypoglycaemia; Hyperinsulinemia hypoglycemia\n'}


{'id': 'HP_0000826', 'url': 'http://purl.obolibrary.org/obo/HP_0000826', 'lbl': 'Precocious puberty', 'desc': 'label: Precocious puberty\ndefinition : The onset of secondary sexual characteristics before a normal age. Although it is difficult to define normal age ranges because of the marked variation with which puberty begins in normal children, precocious puberty can be defined as the onset of puberty before the age of 8 years in girls or 9 years in boys.\nsynonyms :Early onset of puberty; Early puberty\n'}


{'id': 'HP_0000828', 'url': 'http://purl.obolibrary.org/obo/HP_0000828', 'lbl': 'Abnormality of the parathyroid gland', 'desc': 'label: Abnormality of the parathyroid gland\ndefinition : An abnormality of the parathyroid gland.\nsynonyms :Parathyroid disease\n'}


{'id': 'HP_0000829', 'url': 'http://purl.obolibrary.org/obo/HP_0000829', 'lbl': 'Hypoparathyroidism', 'desc': 'label: Hypoparathyroidism\ndefinition : A condition caused by a deficiency of parathyroid hormone characterized by hypocalcemia and hyperphosphatemia.\nsynonyms :Decreased parathyroid hormone secretion; Low parathyroid hormone\n'}


{'id': 'HP_0000830', 'url': 'http://purl.obolibrary.org/obo/HP_0000830', 'lbl': 'Anterior hypopituitarism', 'desc': 'label: Anterior hypopituitarism\ndefinition : A condition of reduced function of the anterior pituitary gland characterized by decreased secretion of one or more of the pituitary hormones growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, prolactin, luteinizing hormone, and follicle-stimulating hormone.\nsynonyms :\n'}


{'id': 'HP_0000831', 'url': 'http://purl.obolibrary.org/obo/HP_0000831', 'lbl': 'Insulin-resistant diabetes mellitus', 'desc': 'label: Insulin-resistant diabetes mellitus\ndefinition : A type of diabetes mellitus related not to lack of insulin but rather to lack of response to insulin on the part of the target tissues of insulin such as muscle, fat, and liver cells. This type of diabetes is typically associated with increases both in blood glucose concentrations as well as in fasting and postprandial serum insulin levels.\nsynonyms :Insulin resistant diabetes; Insulin resistant diabetes mellitus; Insulin-resistant diabetes\n'}


{'id': 'HP_0000832', 'url': 'http://purl.obolibrary.org/obo/HP_0000832', 'lbl': 'Primary hypothyroidism', 'desc': 'label: Primary hypothyroidism\ndefinition : A type of hypothyroidism that results from a defect in the thyroid gland.\nsynonyms :\n'}


{'id': 'HP_0000833', 'url': 'http://purl.obolibrary.org/obo/HP_0000833', 'lbl': 'obsolete Glucose intolerance', 'desc': 'label: obsolete Glucose intolerance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000834', 'url': 'http://purl.obolibrary.org/obo/HP_0000834', 'lbl': 'Abnormality of the adrenal glands', 'desc': 'label: Abnormality of the adrenal glands\ndefinition : Abnormality of the adrenal glands, i.e., of the endocrine glands located at the top of the kindneys.\nsynonyms :Adrenal abnormalities; Adrenal gland disease\n'}


{'id': 'HP_0000835', 'url': 'http://purl.obolibrary.org/obo/HP_0000835', 'lbl': 'Adrenal hypoplasia', 'desc': 'label: Adrenal hypoplasia\ndefinition : Developmental hypoplasia of the adrenal glands.\nsynonyms :Adrenal gland hypoplasia; Hypoplastic adrenal glands; Small adrenal glands; Underdeveloped adrenal glands\n'}


{'id': 'HP_0000836', 'url': 'http://purl.obolibrary.org/obo/HP_0000836', 'lbl': 'Hyperthyroidism', 'desc': "label: Hyperthyroidism\ndefinition : An abnormality of thyroid physiology characterized by excessive secretion of the thyroid hormones thyroxine (i.e., T4) and/or 3,3',5-triiodo-L-thyronine zwitterion (i.e., triiodothyronine or T3).\nsynonyms :Overactive thyroid\n"}


{'id': 'HP_0000837', 'url': 'http://purl.obolibrary.org/obo/HP_0000837', 'lbl': 'Increased circulating gonadotropin level', 'desc': 'label: Increased circulating gonadotropin level\ndefinition : Overproduction of gonadotropins (FSH, LH) by the anterior pituitary gland.\nsynonyms :Elevated gonadotropins; Elevated serum gonadotropins; Gonadotropin excess; Increased circulating gonadotropin level\n'}


{'id': 'HP_0000839', 'url': 'http://purl.obolibrary.org/obo/HP_0000839', 'lbl': 'Pituitary dwarfism', 'desc': 'label: Pituitary dwarfism\ndefinition : A type of reduced stature with normal proportions related to dysfunction of the pituitary gland related to either an isolated defect in the secretion of growth hormone or to panhypopituitarism, i.e., a deficit of all the anterior pituitary hormones.\nsynonyms :\n'}


{'id': 'HP_0000840', 'url': 'http://purl.obolibrary.org/obo/HP_0000840', 'lbl': 'Adrenogenital syndrome', 'desc': 'label: Adrenogenital syndrome\ndefinition : Adrenogenital syndrome is also known as congenital adrenal hyperplasia, which results from disorders of steroid hormone production in the adrenal glands leading to a deficiency of cortisol. The pituitary gland reacts by increased secretion of corticotropin, which in turn causes the adrenal glands to overproduce certain intermediary hormones which have testosterone-like effects.\nsynonyms :\n'}


{'id': 'HP_0000841', 'url': 'http://purl.obolibrary.org/obo/HP_0000841', 'lbl': 'Hyperactive renin-angiotensin system', 'desc': 'label: Hyperactive renin-angiotensin system\ndefinition : An abnormally increased activity of the renin-angiotensin system, causing hypertension by a combination of volume excess and vasoconstrictor mechanisms.\nsynonyms :Increased plasma renin activity\n'}


{'id': 'HP_0000842', 'url': 'http://purl.obolibrary.org/obo/HP_0000842', 'lbl': 'Hyperinsulinemia', 'desc': 'label: Hyperinsulinemia\ndefinition : An increased concentration of insulin in the blood.\nsynonyms :Elevated insulin level\n'}


{'id': 'HP_0000843', 'url': 'http://purl.obolibrary.org/obo/HP_0000843', 'lbl': 'Hyperparathyroidism', 'desc': 'label: Hyperparathyroidism\ndefinition : Excessive production of parathyroid hormone (PTH) by the parathyroid glands.\nsynonyms :Elevated blood parathyroid hormone level\n'}


{'id': 'HP_0000845', 'url': 'http://purl.obolibrary.org/obo/HP_0000845', 'lbl': 'Elevated circulating growth hormone concentration', 'desc': 'label: Elevated circulating growth hormone concentration\ndefinition : Acromegaly is a condition resulting from overproduction of growth hormone by the pituitary gland in persons with closed epiphyses, and consists chiefly in the enlargement of the distal parts of the body. The circumference of the skull increases, the nose becomes broad, the tongue becomes enlarged, the facial features become coarsened, the mandible grows excessively, and the teeth become separated. The fingers and toes grow chiefly in thickness.\nsynonyms :Elevated circulating somatotropin concentration; Growth hormone excess; Somatotropin excess\n'}


{'id': 'HP_0000846', 'url': 'http://purl.obolibrary.org/obo/HP_0000846', 'lbl': 'Adrenal insufficiency', 'desc': 'label: Adrenal insufficiency\ndefinition : Insufficient production of steroid hormones (primarily cortisol) by the adrenal glands.\nsynonyms :Hypoadrenalism\n'}


{'id': 'HP_0000847', 'url': 'http://purl.obolibrary.org/obo/HP_0000847', 'lbl': 'Abnormality of renin-angiotensin system', 'desc': 'label: Abnormality of renin-angiotensin system\ndefinition : An abnormality of the renin-angiotensin system.\nsynonyms :Abnormality of the renin-aldosterone axis\n'}


{'id': 'HP_0000848', 'url': 'http://purl.obolibrary.org/obo/HP_0000848', 'lbl': 'Increased circulating renin level', 'desc': 'label: Increased circulating renin level\ndefinition : An increased level of renin in the blood.\nsynonyms :Elevated blood renin level; Elevated plasma renin; Hyperreninemia; Increased plasma renin; Increased serum renin\n'}


{'id': 'HP_0000849', 'url': 'http://purl.obolibrary.org/obo/HP_0000849', 'lbl': 'Adrenocortical abnormality', 'desc': 'label: Adrenocortical abnormality\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000851', 'url': 'http://purl.obolibrary.org/obo/HP_0000851', 'lbl': 'Congenital hypothyroidism', 'desc': 'label: Congenital hypothyroidism\ndefinition : A type of hypothyroidism with congenital onset.\nsynonyms :Hypothyroidism, congenital; Underactive thyroid gland from birth\n'}


{'id': 'HP_0000852', 'url': 'http://purl.obolibrary.org/obo/HP_0000852', 'lbl': 'Pseudohypoparathyroidism', 'desc': 'label: Pseudohypoparathyroidism\ndefinition : A condition characterized by resistance to the action of parathyroid hormone, in which there is hypocalcemia, hyperphosphatemia, and (appropriately) high levels of parathyroid hormone.\nsynonyms :\n'}


{'id': 'HP_0000853', 'url': 'http://purl.obolibrary.org/obo/HP_0000853', 'lbl': 'Goiter', 'desc': 'label: Goiter\ndefinition : An enlargement of the thyroid gland.\nsynonyms :Enlarged thyroid gland in neck; Goitre; Thyroid goiter; Thyroid goitre\n'}


{'id': 'HP_0000854', 'url': 'http://purl.obolibrary.org/obo/HP_0000854', 'lbl': 'Thyroid adenoma', 'desc': 'label: Thyroid adenoma\ndefinition : The presence of a adenoma of the thyroid gland.\nsynonyms :\n'}


{'id': 'HP_0000855', 'url': 'http://purl.obolibrary.org/obo/HP_0000855', 'lbl': 'Insulin resistance', 'desc': 'label: Insulin resistance\ndefinition : Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.\nsynonyms :Body fails to respond to insulin\n'}


{'id': 'HP_0000857', 'url': 'http://purl.obolibrary.org/obo/HP_0000857', 'lbl': 'Neonatal insulin-dependent diabetes mellitus', 'desc': 'label: Neonatal insulin-dependent diabetes mellitus\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000858', 'url': 'http://purl.obolibrary.org/obo/HP_0000858', 'lbl': 'Irregular menstruation', 'desc': 'label: Irregular menstruation\ndefinition : Abnormally high variation in the amount of time between periods.\nsynonyms :Irregular menses; Irregular periods; Menstrual irregularities; Menstrual irregularity\n'}


{'id': 'HP_0000859', 'url': 'http://purl.obolibrary.org/obo/HP_0000859', 'lbl': 'Hyperaldosteronism', 'desc': 'label: Hyperaldosteronism\ndefinition : Overproduction of the mineralocorticoid aldosterone by the adrenal cortex.\nsynonyms :Elevated plasma aldosterone; Increased aldosterone; Increased aldosterone production; Mineralocorticoid excess\n'}


{'id': 'HP_0000860', 'url': 'http://purl.obolibrary.org/obo/HP_0000860', 'lbl': 'Parathyroid hypoplasia', 'desc': 'label: Parathyroid hypoplasia\ndefinition : Developmental hypoplasia of the parathyroid gland.\nsynonyms :Small parathyroid glands; Underdeveloped parathyroid glands\n'}


{'id': 'HP_0000863', 'url': 'http://purl.obolibrary.org/obo/HP_0000863', 'lbl': 'Central diabetes insipidus', 'desc': 'label: Central diabetes insipidus\ndefinition : A form of diabetes insipidus related to a failure of vasopressin (AVP) release from the hypothalamus.\nsynonyms :Neurohypophyseal diabetes insipidus\n'}


{'id': 'HP_0000864', 'url': 'http://purl.obolibrary.org/obo/HP_0000864', 'lbl': 'Abnormality of the hypothalamus-pituitary axis', 'desc': 'label: Abnormality of the hypothalamus-pituitary axis\ndefinition : Abnormality of the pituitary gland (also known as hypophysis), which is an endocrine gland that protrudes from the bottom of the hypothalamus at the base of the brain. The pituitary gland secretes the hormones ACTH, TSH, PRL, GH, endorphins, FSH, LH, oxytocin, and antidiuretic hormone. The secretion of hormones from the anterior pituitary is under the strict control of hypothalamic hormones, and the posterior pituitary is essentially an extension of the hypothalamus, so that hypothalamus and pituitary gland may be regarded as a functional unit.\nsynonyms :\n'}


{'id': 'HP_0000866', 'url': 'http://purl.obolibrary.org/obo/HP_0000866', 'lbl': 'Euthyroid multinodular goiter', 'desc': 'label: Euthyroid multinodular goiter\ndefinition : \nsynonyms :Euthyroid multinodular goitre\n'}


{'id': 'HP_0000867', 'url': 'http://purl.obolibrary.org/obo/HP_0000867', 'lbl': 'Secondary hyperparathyroidism', 'desc': 'label: Secondary hyperparathyroidism\ndefinition : Secondary hyperparathyroidism refers to the production of higher than normal levels of parathyroid hormone in the presence of hypocalcemia.\nsynonyms :\n'}


{'id': 'HP_0000868', 'url': 'http://purl.obolibrary.org/obo/HP_0000868', 'lbl': 'Decreased fertility in females', 'desc': 'label: Decreased fertility in females\ndefinition : \nsynonyms :Decreased fertility in females; Reduced fertility in females\n'}


{'id': 'HP_0000869', 'url': 'http://purl.obolibrary.org/obo/HP_0000869', 'lbl': 'Secondary amenorrhea', 'desc': 'label: Secondary amenorrhea\ndefinition : \nsynonyms :Previous menstrual periods stop\n'}


{'id': 'HP_0000870', 'url': 'http://purl.obolibrary.org/obo/HP_0000870', 'lbl': 'Increased circulating prolactin concentration', 'desc': 'label: Increased circulating prolactin concentration\ndefinition : The presence of abnormally increased levels of prolactin in the blood. Prolactin is a peptide hormone produced by the anterior pituitary gland that plays a role in breast development and lactation during pregnancy.\nsynonyms :Hyperprolactinaemia; Hyperprolactinemia; Prolactin excess\n'}


{'id': 'HP_0000871', 'url': 'http://purl.obolibrary.org/obo/HP_0000871', 'lbl': 'Panhypopituitarism', 'desc': 'label: Panhypopituitarism\ndefinition : A pituitary functional deficit affecting all the anterior pituitary hormones (growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, adrenocorticotropic hormone, and prolactin).\nsynonyms :\n'}


{'id': 'HP_0000872', 'url': 'http://purl.obolibrary.org/obo/HP_0000872', 'lbl': 'Hashimoto thyroiditis', 'desc': "label: Hashimoto thyroiditis\ndefinition : A chronic, autoimmune type of thyroiditis associated with hypothyroidism.\nsynonyms :Chronic lymphocytic thyroiditis; Hashimoto's thyroiditis\n"}


{'id': 'HP_0000873', 'url': 'http://purl.obolibrary.org/obo/HP_0000873', 'lbl': 'Diabetes insipidus', 'desc': 'label: Diabetes insipidus\ndefinition : A state of excessive water intake and hypotonic (dilute) polyuria. Diabetes insipidus may be due to failure of vasopressin (AVP) release (central or neurogenic diabetes insipidus) or to a failure of the kidney to respond to AVP (nephrogenic diabetes insipidus).\nsynonyms :\n'}


{'id': 'HP_0000875', 'url': 'http://purl.obolibrary.org/obo/HP_0000875', 'lbl': 'Episodic hypertension', 'desc': 'label: Episodic hypertension\ndefinition : \nsynonyms :Intermittent high blood pressure\n'}


{'id': 'HP_0000876', 'url': 'http://purl.obolibrary.org/obo/HP_0000876', 'lbl': 'Oligomenorrhea', 'desc': 'label: Oligomenorrhea\ndefinition : Infrequent menses (less than 6 per year or more than 35 days between cycles).\nsynonyms :Light or infrequent menstrual periods\n'}


{'id': 'HP_0000877', 'url': 'http://purl.obolibrary.org/obo/HP_0000877', 'lbl': 'Insulin-resistant diabetes mellitus at puberty', 'desc': 'label: Insulin-resistant diabetes mellitus at puberty\ndefinition : \nsynonyms :Insulin-resistant diabetes mellitus at puberty\n'}


{'id': 'HP_0000878', 'url': 'http://purl.obolibrary.org/obo/HP_0000878', 'lbl': '11 pairs of ribs', 'desc': 'label: 11 pairs of ribs\ndefinition : Presence of only 11 pairs of ribs.\nsynonyms :11 pairs of ribs\n'}


{'id': 'HP_0000879', 'url': 'http://purl.obolibrary.org/obo/HP_0000879', 'lbl': 'Short sternum', 'desc': 'label: Short sternum\ndefinition : Decreased inferosuperior length of the sternum.\nsynonyms :Short sternum; Hypoplastic sternum\n'}


{'id': 'HP_0000882', 'url': 'http://purl.obolibrary.org/obo/HP_0000882', 'lbl': 'Hypoplastic scapulae', 'desc': 'label: Hypoplastic scapulae\ndefinition : Underdeveloped scapula.\nsynonyms :Hypoplastic scapula; Scapular hypoplasia; Short scapulae; Small scapula; Small scapulae; Small shoulder blade\n'}


{'id': 'HP_0000883', 'url': 'http://purl.obolibrary.org/obo/HP_0000883', 'lbl': 'Thin ribs', 'desc': 'label: Thin ribs\ndefinition : Ribs with a reduced diameter.\nsynonyms :Slender ribs; Thin ribs\n'}


{'id': 'HP_0000884', 'url': 'http://purl.obolibrary.org/obo/HP_0000884', 'lbl': 'Prominent sternum', 'desc': 'label: Prominent sternum\ndefinition : \nsynonyms :Prominent sternum; Sternal protrusion\n'}


{'id': 'HP_0000885', 'url': 'http://purl.obolibrary.org/obo/HP_0000885', 'lbl': 'Broad ribs', 'desc': 'label: Broad ribs\ndefinition : Increased width of ribs\nsynonyms :Broad ribs; Wide ribs\n'}


{'id': 'HP_0000886', 'url': 'http://purl.obolibrary.org/obo/HP_0000886', 'lbl': 'Deformed rib cage', 'desc': 'label: Deformed rib cage\ndefinition : Malformation of the rib cage.\nsynonyms :Deformed rib cage\n'}


{'id': 'HP_0000887', 'url': 'http://purl.obolibrary.org/obo/HP_0000887', 'lbl': 'Cupped ribs', 'desc': 'label: Cupped ribs\ndefinition : Wide, concave rib end.\nsynonyms :Cupped ribs; Rib cupping; Rib flaring\n'}


{'id': 'HP_0000888', 'url': 'http://purl.obolibrary.org/obo/HP_0000888', 'lbl': 'Horizontal ribs', 'desc': 'label: Horizontal ribs\ndefinition : A horizontal (flat) conformation of the ribs, the long curved bones that form the rib cage and normally progressively oblique (slanted) from ribs 1 through 9, then less slanted through rib 12.\nsynonyms :Horizontal ribs\n'}


{'id': 'HP_0000889', 'url': 'http://purl.obolibrary.org/obo/HP_0000889', 'lbl': 'Abnormal clavicle morphology', 'desc': 'label: Abnormal clavicle morphology\ndefinition : Any abnormality of the clavicles (collar bones).\nsynonyms :Abnormal clavicles; Abnormal collarbone; Abnormality of the clavicle\n'}


{'id': 'HP_0000890', 'url': 'http://purl.obolibrary.org/obo/HP_0000890', 'lbl': 'Long clavicles', 'desc': 'label: Long clavicles\ndefinition : Increased length of the clavicles.\nsynonyms :Elongated clavicles; Long collarbone\n'}


{'id': 'HP_0000891', 'url': 'http://purl.obolibrary.org/obo/HP_0000891', 'lbl': 'Cervical ribs', 'desc': 'label: Cervical ribs\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000892', 'url': 'http://purl.obolibrary.org/obo/HP_0000892', 'lbl': 'Bifid ribs', 'desc': 'label: Bifid ribs\ndefinition : A bifid rib refers to cleavage of the sternal end of a rib, usually unilateral. Bifid ribs are usually asymptomatic, and are often discovered incidentally by chest x-ray.\nsynonyms :Cleft ribs; Split ribs\n'}


{'id': 'HP_0000893', 'url': 'http://purl.obolibrary.org/obo/HP_0000893', 'lbl': 'Bulging of the costochondral junction', 'desc': 'label: Bulging of the costochondral junction\ndefinition : Abnormal outward curving (protuberance) of the junction of ribs and costal cartilage.\nsynonyms :\n'}


{'id': 'HP_0000894', 'url': 'http://purl.obolibrary.org/obo/HP_0000894', 'lbl': 'Short clavicles', 'desc': 'label: Short clavicles\ndefinition : Reduced length of the clavicles.\nsynonyms :Clavicular hypoplasia; Hypoplastic clavicles; Short collarbone; Underdeveloped clavicles\n'}


{'id': 'HP_0000895', 'url': 'http://purl.obolibrary.org/obo/HP_0000895', 'lbl': 'Lateral clavicle hook', 'desc': 'label: Lateral clavicle hook\ndefinition : An excessive upward convexity of the lateral clavicle.\nsynonyms :Handlebar clavicle; Hook-shaped clavicle; Hook-shaped collarbone; Hooked clavicle\n'}


{'id': 'HP_0000896', 'url': 'http://purl.obolibrary.org/obo/HP_0000896', 'lbl': 'Rib exostoses', 'desc': 'label: Rib exostoses\ndefinition : Multiple circumscribed bony excrescences located in the ribs.\nsynonyms :\n'}


{'id': 'HP_0000897', 'url': 'http://purl.obolibrary.org/obo/HP_0000897', 'lbl': 'Rachitic rosary', 'desc': 'label: Rachitic rosary\ndefinition : A row of beadlike prominences at the junction of a rib and its cartilage (i.e., enlarged costochondral joints), resembling a rosary.\nsynonyms :\n'}


{'id': 'HP_0000900', 'url': 'http://purl.obolibrary.org/obo/HP_0000900', 'lbl': 'Thickened ribs', 'desc': 'label: Thickened ribs\ndefinition : Increased thickness (diameter) of ribs.\nsynonyms :\n'}


{'id': 'HP_0000902', 'url': 'http://purl.obolibrary.org/obo/HP_0000902', 'lbl': 'Rib fusion', 'desc': 'label: Rib fusion\ndefinition : Complete or partial merging of adjacent ribs.\nsynonyms :Fused ribs; Rib fusion\n'}


{'id': 'HP_0000904', 'url': 'http://purl.obolibrary.org/obo/HP_0000904', 'lbl': 'Flaring of rib cage', 'desc': 'label: Flaring of rib cage\ndefinition : The presence of wide, concave anterior rib ends.\nsynonyms :Anterior flaring of ribs; Flaring of rib cage\n'}


{'id': 'HP_0000905', 'url': 'http://purl.obolibrary.org/obo/HP_0000905', 'lbl': 'Progressive clavicular acroosteolysis', 'desc': 'label: Progressive clavicular acroosteolysis\ndefinition : Progressive bone resorption in the distal part of the clavicle.\nsynonyms :Progressive acroosteolysis of the clavicle\n'}


{'id': 'HP_0000907', 'url': 'http://purl.obolibrary.org/obo/HP_0000907', 'lbl': 'Anterior rib cupping', 'desc': 'label: Anterior rib cupping\ndefinition : Wide, concave anterior rib end.\nsynonyms :Anterior cupping of ribs; Anteriorly splayed ribs\n'}


{'id': 'HP_0000910', 'url': 'http://purl.obolibrary.org/obo/HP_0000910', 'lbl': 'Wide-cupped costochondral junctions', 'desc': 'label: Wide-cupped costochondral junctions\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000911', 'url': 'http://purl.obolibrary.org/obo/HP_0000911', 'lbl': 'Flat glenoid fossa', 'desc': 'label: Flat glenoid fossa\ndefinition : Abnormally flat configuration of the glenoid fossa, also known as the glenoid cavity, which is the articular surface of the scapula that articulates with the head of the humerus.\nsynonyms :\n'}


{'id': 'HP_0000912', 'url': 'http://purl.obolibrary.org/obo/HP_0000912', 'lbl': 'Sprengel anomaly', 'desc': 'label: Sprengel anomaly\ndefinition : A congenital skeletal deformity characterized by the elevation of one scapula (thus, one scapula is located superior to the other).\nsynonyms :Congenital, upward displacement of the scapula; High scapula; High shoulder blade; Sprengel deformity\n'}


{'id': 'HP_0000913', 'url': 'http://purl.obolibrary.org/obo/HP_0000913', 'lbl': 'Posterior rib fusion', 'desc': 'label: Posterior rib fusion\ndefinition : Complete or partial merging of the posterior part of adjacent ribs.\nsynonyms :\n'}


{'id': 'HP_0000914', 'url': 'http://purl.obolibrary.org/obo/HP_0000914', 'lbl': 'Shield chest', 'desc': 'label: Shield chest\ndefinition : A broad chest.\nsynonyms :Shield chest; Broad chest\n'}


{'id': 'HP_0000915', 'url': 'http://purl.obolibrary.org/obo/HP_0000915', 'lbl': 'Pectus excavatum of inferior sternum', 'desc': 'label: Pectus excavatum of inferior sternum\ndefinition : Pectus excavatum (defect of the chest wall characterized by depression of the sternum) affecting primarily the inferior region of the sternum.\nsynonyms :Pectus excavatum inferiorly\n'}


{'id': 'HP_0000916', 'url': 'http://purl.obolibrary.org/obo/HP_0000916', 'lbl': 'Broad clavicles', 'desc': 'label: Broad clavicles\ndefinition : Increased width (cross-sectional diameter) of the clavicles.\nsynonyms :Broad collarbone\n'}


{'id': 'HP_0000917', 'url': 'http://purl.obolibrary.org/obo/HP_0000917', 'lbl': 'Superior pectus carinatum', 'desc': 'label: Superior pectus carinatum\ndefinition : Pectus carinatum affecting primarily the superior part of the sternum.\nsynonyms :Pectus carinatum superiorly\n'}


{'id': 'HP_0000918', 'url': 'http://purl.obolibrary.org/obo/HP_0000918', 'lbl': 'Scapular exostoses', 'desc': 'label: Scapular exostoses\ndefinition : The presence of multiple exostoses on the scapula. An exostosis is a benign growth the projects outward from the bone surface. It is capped by cartilage.\nsynonyms :Scapulae exostoses; Shoulder bone exostoes\n'}


{'id': 'HP_0000919', 'url': 'http://purl.obolibrary.org/obo/HP_0000919', 'lbl': 'Abnormality of the costochondral junction', 'desc': 'label: Abnormality of the costochondral junction\ndefinition : Any anomaly of the costochondral junction. The costochondral junctions are located between the distal part of the ribs and the costal cartilages, which are bars of hyaline cartilage that connect the ribs to the sternum.\nsynonyms :Costochondral juctions abnormal\n'}


{'id': 'HP_0000920', 'url': 'http://purl.obolibrary.org/obo/HP_0000920', 'lbl': 'Enlargement of the costochondral junction', 'desc': 'label: Enlargement of the costochondral junction\ndefinition : Abnormally increased size of the costochondral junctions, which are located between the distal part of the ribs and the costal cartilages, which are bars of hyaline cartilage that connect the ribs to the sternum.\nsynonyms :Costochondral thickening; Enlarged costochondral junctions; Prominent costochondral junction; Wide costochondral junctions; Widened costochondral junction\n'}


{'id': 'HP_0000921', 'url': 'http://purl.obolibrary.org/obo/HP_0000921', 'lbl': 'Missing ribs', 'desc': 'label: Missing ribs\ndefinition : A developmental anomaly with absence of one or more ribs.\nsynonyms :Absent ribs; Decreased rib number; Missing ribs\n'}


{'id': 'HP_0000922', 'url': 'http://purl.obolibrary.org/obo/HP_0000922', 'lbl': 'Posterior rib cupping', 'desc': 'label: Posterior rib cupping\ndefinition : Wide, concave posterior rib end.\nsynonyms :Anterior and posterior rib cupping\n'}


{'id': 'HP_0000923', 'url': 'http://purl.obolibrary.org/obo/HP_0000923', 'lbl': 'Beaded ribs', 'desc': 'label: Beaded ribs\ndefinition : The presence of a row of multiple rounded expansions (beadlike prominences) at the junction of a rib and its cartilage.\nsynonyms :\n'}


{'id': 'HP_0000924', 'url': 'http://purl.obolibrary.org/obo/HP_0000924', 'lbl': 'Abnormality of the skeletal system', 'desc': 'label: Abnormality of the skeletal system\ndefinition : An abnormality of the skeletal system.\nsynonyms :Abnormality of the skeletal system; Skeletal abnormalities; Skeletal anomalies\n'}


{'id': 'HP_0000925', 'url': 'http://purl.obolibrary.org/obo/HP_0000925', 'lbl': 'Abnormality of the vertebral column', 'desc': 'label: Abnormality of the vertebral column\ndefinition : Any abnormality of the vertebral column.\nsynonyms :Abnormal spine; Abnormal vertebral column; Abnormality of the spine; Abnormality of the vertebral column; Abnormality of the backbone\n'}


{'id': 'HP_0000926', 'url': 'http://purl.obolibrary.org/obo/HP_0000926', 'lbl': 'Platyspondyly', 'desc': 'label: Platyspondyly\ndefinition : A flattened vertebral body shape with reduced distance between the vertebral endplates.\nsynonyms :Flat vertebral bodies; Flattened vertebrae; Flattened vertebral bodies\n'}


{'id': 'HP_0000927', 'url': 'http://purl.obolibrary.org/obo/HP_0000927', 'lbl': 'Abnormality of skeletal maturation', 'desc': 'label: Abnormality of skeletal maturation\ndefinition : The bones of the skeleton undergo a series of characteristic changes in size, shape, and calcification from fetal life until puberty. An abnormality of this process can include delayed or accelerated skeletal maturation, or deviation of some, but not all bones from the expected patterns of maturation.\nsynonyms :Abnormality of skeletal maturation\n'}


{'id': 'HP_0000929', 'url': 'http://purl.obolibrary.org/obo/HP_0000929', 'lbl': 'Abnormal skull morphology', 'desc': 'label: Abnormal skull morphology\ndefinition : An abnormality of the skull, the bony framework of the head which is comprised of the neurocranium (with eight cranial bones) and the viscerocranium (facial skeleton) that comprises fourteen facial bones with the mandible as its largest bone.\nsynonyms :Abnormality of the skull; Abnormality of the skull bones\n'}


{'id': 'HP_0000930', 'url': 'http://purl.obolibrary.org/obo/HP_0000930', 'lbl': 'Elevated imprint of the transverse sinuses', 'desc': 'label: Elevated imprint of the transverse sinuses\ndefinition : \nsynonyms :Elevated imprint of occipital bone over the transverse sinuses; Elevated imprint of posterior skull bones over the transverse sinuses; Thinning and bulging of occipital bone over the transverse sinuses; Thinning and bulging of posterior skull bones over the transverse sinuses\n'}


{'id': 'HP_0000931', 'url': 'http://purl.obolibrary.org/obo/HP_0000931', 'lbl': 'Thinning and bulging of the posterior fossa bones', 'desc': 'label: Thinning and bulging of the posterior fossa bones\ndefinition : \nsynonyms :Thinning and bulging of posterior fossa bones; Thinning and bulging of posterior skull bones; Thinning and bulging of occipital bone of skull\n'}


{'id': 'HP_0000932', 'url': 'http://purl.obolibrary.org/obo/HP_0000932', 'lbl': 'Abnormal posterior cranial fossa morphology', 'desc': 'label: Abnormal posterior cranial fossa morphology\ndefinition : An abnormality of the fossa cranii posterior (the posterior fossa), which is made up primarily of the occipital bone and which surrounds to the foramen magnum.\nsynonyms :Abnormality of the posterior cranial fossa; Abnormality of the posterior fossa; Posterior fossa anomaly\n'}


{'id': 'HP_0000933', 'url': 'http://purl.obolibrary.org/obo/HP_0000933', 'lbl': 'Posterior fossa cyst at the fourth ventricle', 'desc': 'label: Posterior fossa cyst at the fourth ventricle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000934', 'url': 'http://purl.obolibrary.org/obo/HP_0000934', 'lbl': 'Chondrocalcinosis', 'desc': 'label: Chondrocalcinosis\ndefinition : Radiographic evidence of articular calcification that represent calcium pyrophosphate depositions in soft tissue surrounding joints and at the insertions of tendons near joints (Entheses/Sharpey fibers) .\nsynonyms :Calcium deposits in joints\n'}


{'id': 'HP_0000935', 'url': 'http://purl.obolibrary.org/obo/HP_0000935', 'lbl': 'Thickened cortex of long bones', 'desc': 'label: Thickened cortex of long bones\ndefinition : Abnormal thickening of the cortex of long bones.\nsynonyms :Broad cortex of long bones; Cortical thickening of the long bones; Thickened cortices of long bones\n'}


{'id': 'HP_0000938', 'url': 'http://purl.obolibrary.org/obo/HP_0000938', 'lbl': 'Osteopenia', 'desc': 'label: Osteopenia\ndefinition : Osteopenia is a term to define bone density that is not normal but also not as low as osteoporosis. By definition from the World Health Organization osteopenia is defined by bone densitometry as a T score -1 to -2.5.\nsynonyms :Generalised osteopenia; Generalized osteopenia; Osteopaenia\n'}


{'id': 'HP_0000939', 'url': 'http://purl.obolibrary.org/obo/HP_0000939', 'lbl': 'Osteoporosis', 'desc': 'label: Osteoporosis\ndefinition : Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility. According to the WHO criteria, osteoporosis is defined as a BMD that lies 2.5 standard deviations or more below the average value for young healthy adults (a T-score below -2.5 SD).\nsynonyms :\n'}


{'id': 'HP_0000940', 'url': 'http://purl.obolibrary.org/obo/HP_0000940', 'lbl': 'Abnormal diaphysis morphology', 'desc': 'label: Abnormal diaphysis morphology\ndefinition : An abnormality of the structure or form of the diaphysis, i.e., of the main or mid-section (shaft) of a long bone.\nsynonyms :Abnormal shape of shaft of long bone; Abnormality involving the diaphyses of the limbs; Abnormality of shaft of long bone of the limbs; Abnormality of the diaphyses; Anomaly of the limb diaphyses; Anomaly of the limb diaphyses morphology\n'}


{'id': 'HP_0000941', 'url': 'http://purl.obolibrary.org/obo/HP_0000941', 'lbl': 'Short diaphyses', 'desc': 'label: Short diaphyses\ndefinition : \nsynonyms :Short shaft of long bone\n'}


{'id': 'HP_0000943', 'url': 'http://purl.obolibrary.org/obo/HP_0000943', 'lbl': 'Dysostosis multiplex', 'desc': 'label: Dysostosis multiplex\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000944', 'url': 'http://purl.obolibrary.org/obo/HP_0000944', 'lbl': 'Abnormal metaphysis morphology', 'desc': 'label: Abnormal metaphysis morphology\ndefinition : An abnormality of one or more metaphysis, i.e., of the somewhat wider portion of a long bone that is adjacent to the epiphyseal growth plate and grows during childhood.\nsynonyms :Abnormality of the wide portion of a long bone\n'}


{'id': 'HP_0000946', 'url': 'http://purl.obolibrary.org/obo/HP_0000946', 'lbl': 'Hypoplastic ilia', 'desc': 'label: Hypoplastic ilia\ndefinition : Underdevelopment of the ilium.\nsynonyms :Small wings of the pelvic girdle; Short and small iliac bones; Small iliac bones\n'}


{'id': 'HP_0000947', 'url': 'http://purl.obolibrary.org/obo/HP_0000947', 'lbl': 'Dumbbell-shaped long bone', 'desc': 'label: Dumbbell-shaped long bone\ndefinition : An abnormal appearance of the long bones with resemblance to a dumbbell, a short bar with a weight at each end. That is, the long bone is shortened and displays flaring (widening) of the metaphyses.\nsynonyms :Dumbbell widening of long bone metaphyses; Dumbbell-shaped long bone\n'}


{'id': 'HP_0000951', 'url': 'http://purl.obolibrary.org/obo/HP_0000951', 'lbl': 'Abnormality of the skin', 'desc': 'label: Abnormality of the skin\ndefinition : An abnormality of the skin.\nsynonyms :Abnormality of the skin; Dermatopathy; Dermopathy; Skin abnormality\n'}


{'id': 'HP_0000952', 'url': 'http://purl.obolibrary.org/obo/HP_0000952', 'lbl': 'Jaundice', 'desc': 'label: Jaundice\ndefinition : Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.\nsynonyms :Icterus; Jaundice; Yellow skin; Yellowing of the skin\n'}


{'id': 'HP_0000953', 'url': 'http://purl.obolibrary.org/obo/HP_0000953', 'lbl': 'Hyperpigmentation of the skin', 'desc': 'label: Hyperpigmentation of the skin\ndefinition : A darkening of the skin related to an increase in melanin production and deposition.\nsynonyms :Cutaneous hyperpigmentation; Hyperpigmented lesion; Increased skin pigmentation; Patchy darkened skin; Skin hyperpigmentation; Melanoderma; Melanodermia\n'}


{'id': 'HP_0000954', 'url': 'http://purl.obolibrary.org/obo/HP_0000954', 'lbl': 'Single transverse palmar crease', 'desc': 'label: Single transverse palmar crease\ndefinition : The distal and proximal transverse palmar creases are merged into a single transverse palmar crease.\nsynonyms :Simian crease; Simian creases; Simian line; Single flexion crease; Single palmar crease; Single palmar creases; Single transverse palmar creases; Transverse palmar crease\n'}


{'id': 'HP_0000956', 'url': 'http://purl.obolibrary.org/obo/HP_0000956', 'lbl': 'Acanthosis nigricans', 'desc': 'label: Acanthosis nigricans\ndefinition : A dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck.\nsynonyms :Darkened and thickened skin; Keratosis nigricans\n'}


{'id': 'HP_0000957', 'url': 'http://purl.obolibrary.org/obo/HP_0000957', 'lbl': 'Cafe-au-lait spot', 'desc': 'label: Cafe-au-lait spot\ndefinition : Cafe-au-lait spots are hyperpigmented lesions that can vary in color from light brown to dark brown with smooth borders and having a size of 1.5 cm or more in adults and 0.5 cm or more in children.\nsynonyms :Birthmark; Flat light-brown mark on skin; Cafe au lait spots; Cafe-au-lait macule; Cafe-au-lait macules; Cafe-au-lait spots\n'}


{'id': 'HP_0000958', 'url': 'http://purl.obolibrary.org/obo/HP_0000958', 'lbl': 'Dry skin', 'desc': 'label: Dry skin\ndefinition : Skin characterized by the lack of natural or normal moisture.\nsynonyms :Dry skin; Xerosis\n'}


{'id': 'HP_0000960', 'url': 'http://purl.obolibrary.org/obo/HP_0000960', 'lbl': 'Sacral dimple', 'desc': 'label: Sacral dimple\ndefinition : A cutaneous indentation resulting from tethering of the skin to underlying structures (bone) of the intergluteal cleft.\nsynonyms :Pilonidal dimple; Spinal dimple\n'}


{'id': 'HP_0000961', 'url': 'http://purl.obolibrary.org/obo/HP_0000961', 'lbl': 'Cyanosis', 'desc': 'label: Cyanosis\ndefinition : Bluish discoloration of the skin and mucosa due to poor circulation or inadequate oxygenation of arterial or capillary blood.\nsynonyms :Blue discoloration of the skin\n'}


{'id': 'HP_0000962', 'url': 'http://purl.obolibrary.org/obo/HP_0000962', 'lbl': 'Hyperkeratosis', 'desc': 'label: Hyperkeratosis\ndefinition : Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum.\nsynonyms :\n'}


{'id': 'HP_0000963', 'url': 'http://purl.obolibrary.org/obo/HP_0000963', 'lbl': 'Thin skin', 'desc': 'label: Thin skin\ndefinition : Reduction in thickness of the skin, generally associated with a loss of suppleness and elasticity of the skin.\nsynonyms :Thin skin\n'}


{'id': 'HP_0000964', 'url': 'http://purl.obolibrary.org/obo/HP_0000964', 'lbl': 'Eczema', 'desc': 'label: Eczema\ndefinition : Eczema is a form of dermatitis. The term eczema is broadly applied to a range of persistent skin conditions and can be related to a number of underlying conditions. Manifestations of eczema can include dryness and recurring skin rashes with redness, skin edema, itching and dryness, crusting, flaking, blistering, cracking, oozing, or bleeding.\nsynonyms :Eczema\n'}


{'id': 'HP_0000965', 'url': 'http://purl.obolibrary.org/obo/HP_0000965', 'lbl': 'Cutis marmorata', 'desc': 'label: Cutis marmorata\ndefinition : A reticular discoloration of the skin with cyanotic (reddish-blue appearing) areas surrounding pale central areas due to dilation of capillary blood vessels and stagnation of blood within the vessels. Cutis marmorata generally occurs on the legs, arms and trunk and is often more severe in cold weather.\nsynonyms :\n'}


{'id': 'HP_0000966', 'url': 'http://purl.obolibrary.org/obo/HP_0000966', 'lbl': 'Hypohidrosis', 'desc': 'label: Hypohidrosis\ndefinition : Abnormally diminished capacity to sweat.\nsynonyms :Decreased ability to sweat; Decreased sweating; Inadequate sweating; Oligohidrosis; Sweating, decreased\n'}


{'id': 'HP_0000967', 'url': 'http://purl.obolibrary.org/obo/HP_0000967', 'lbl': 'Petechiae', 'desc': 'label: Petechiae\ndefinition : Petechiae are pinpoint-sized reddish/purple spots, resembling a rash, that appear just under the skin or a mucous membrane when capillaries have ruptured and some superficial bleeding into the skin has happened. This term refers to an abnormally increased susceptibility to developing petechiae.\nsynonyms :\n'}


{'id': 'HP_0000968', 'url': 'http://purl.obolibrary.org/obo/HP_0000968', 'lbl': 'Ectodermal dysplasia', 'desc': 'label: Ectodermal dysplasia\ndefinition : Ectodermal dysplasia is a group of conditions in which there is abnormal development of the skin, hair, nails, teeth, or sweat glands.\nsynonyms :\n'}


{'id': 'HP_0000969', 'url': 'http://purl.obolibrary.org/obo/HP_0000969', 'lbl': 'Edema', 'desc': 'label: Edema\ndefinition : An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body.\nsynonyms :Dropsy; Fluid retention; Hydrops; Oedema; Water retention\n'}


{'id': 'HP_0000970', 'url': 'http://purl.obolibrary.org/obo/HP_0000970', 'lbl': 'Anhidrosis', 'desc': 'label: Anhidrosis\ndefinition : Inability to sweat.\nsynonyms :Anhydrosis; Lack of sweating; Sudomotor dysfunction; Sweating dysfunction\n'}


{'id': 'HP_0000971', 'url': 'http://purl.obolibrary.org/obo/HP_0000971', 'lbl': 'Abnormal sweat gland morphology', 'desc': 'label: Abnormal sweat gland morphology\ndefinition : Any structural abnormality of the sweat gland.\nsynonyms :Abnormality of the sweat gland; Abnormalities of sweating; Sweat gland disease\n'}


{'id': 'HP_0000972', 'url': 'http://purl.obolibrary.org/obo/HP_0000972', 'lbl': 'Palmoplantar hyperkeratosis', 'desc': 'label: Palmoplantar hyperkeratosis\ndefinition : Abnormal thickening of the skin localized to the palm of the hand and the sole of the foot.\nsynonyms :Hyperkeratosis of palms and soles; Hyperkeratosis of the palms and soles; Palmoplantar keratoses; Palmoplantar keratosis; Thick palms and soles; Thickened palms and soles; Thickening of the outer layer of the skin of the palms and soles\n'}


{'id': 'HP_0000973', 'url': 'http://purl.obolibrary.org/obo/HP_0000973', 'lbl': 'Cutis laxa', 'desc': 'label: Cutis laxa\ndefinition : Wrinkled, redundant, inelastic and sagging skin.\nsynonyms :Hanging skin; Chalazoderma; Cutaneous laxity; Dermatochalasia; Dermatomegaly; Elastolysis; Generalised elastolysis; Generalized elastolysis; Hypoelastic skin; Inelastic skin; Lax skin; Loose and inelastic skin; Loose skin; Skin laxity\n'}


{'id': 'HP_0000974', 'url': 'http://purl.obolibrary.org/obo/HP_0000974', 'lbl': 'Hyperextensible skin', 'desc': 'label: Hyperextensible skin\ndefinition : A condition in which the skin can be stretched beyond normal, and then returns to its initial position.\nsynonyms :Hyperelastic skin; Skin hyperelasticity; Skin hyperextensibility; Stretchable skin\n'}


{'id': 'HP_0000975', 'url': 'http://purl.obolibrary.org/obo/HP_0000975', 'lbl': 'Hyperhidrosis', 'desc': 'label: Hyperhidrosis\ndefinition : Abnormal excessive perspiration (sweating) despite the lack of appropriate stimuli like hot and humid weather.\nsynonyms :Diaphoresis; Excessive sweating; Increased sweating; Profuse sweating; Sweating; Sweating profusely; Sweating, increased\n'}


{'id': 'HP_0000976', 'url': 'http://purl.obolibrary.org/obo/HP_0000976', 'lbl': 'Eczematoid dermatitis', 'desc': 'label: Eczematoid dermatitis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0000977', 'url': 'http://purl.obolibrary.org/obo/HP_0000977', 'lbl': 'Soft skin', 'desc': 'label: Soft skin\ndefinition : Subjective impression of increased softness upon palpation of the skin.\nsynonyms :Soft skin; Velvety skin; Velvety skin texture\n'}


{'id': 'HP_0000978', 'url': 'http://purl.obolibrary.org/obo/HP_0000978', 'lbl': 'Bruising susceptibility', 'desc': 'label: Bruising susceptibility\ndefinition : An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.\nsynonyms :Bruisability; Bruise easily; Bruising susceptibility; Easy bruisability; Easy bruising\n'}


{'id': 'HP_0000979', 'url': 'http://purl.obolibrary.org/obo/HP_0000979', 'lbl': 'Purpura', 'desc': 'label: Purpura\ndefinition : Purpura (from Latin: purpura, meaning "purple") is the appearance of red or purple discolorations on the skin that do not blanch on applying pressure. They are caused by bleeding underneath the skin. This term refers to an abnormally increased susceptibility to developing purpura. Purpura are larger than petechiae.\nsynonyms :Blood spots; Red or purple spots on the skin\n'}


{'id': 'HP_0000980', 'url': 'http://purl.obolibrary.org/obo/HP_0000980', 'lbl': 'Pallor', 'desc': 'label: Pallor\ndefinition : Abnormally pale skin.\nsynonyms :Paleness; Skin paleness\n'}


{'id': 'HP_0000982', 'url': 'http://purl.obolibrary.org/obo/HP_0000982', 'lbl': 'Palmoplantar keratoderma', 'desc': 'label: Palmoplantar keratoderma\ndefinition : Abnormal thickening of the skin of the palms of the hands and the soles of the feet.\nsynonyms :Palmar and plantar keratoderma; Thickening of palms and soles\n'}


{'id': 'HP_0000987', 'url': 'http://purl.obolibrary.org/obo/HP_0000987', 'lbl': 'Atypical scarring of skin', 'desc': 'label: Atypical scarring of skin\ndefinition : Atypically scarred skin .\nsynonyms :Atypical scarring; Atypical scarring of skin\n'}


{'id': 'HP_0000988', 'url': 'http://purl.obolibrary.org/obo/HP_0000988', 'lbl': 'Skin rash', 'desc': 'label: Skin rash\ndefinition : A red eruption of the skin.\nsynonyms :Rash; Skin rash\n'}


{'id': 'HP_0000989', 'url': 'http://purl.obolibrary.org/obo/HP_0000989', 'lbl': 'Pruritus', 'desc': 'label: Pruritus\ndefinition : Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased disposition to experience pruritus.\nsynonyms :Itching; Itchy skin; Skin itching\n'}


{'id': 'HP_0000991', 'url': 'http://purl.obolibrary.org/obo/HP_0000991', 'lbl': 'Xanthomatosis', 'desc': 'label: Xanthomatosis\ndefinition : The presence of multiple xanthomas (xanthomata) in the skin. Xanthomas are yellowish, firm, lipid-laden nodules in the skin.\nsynonyms :Xanthomata; Yellow bumps of fatty deposits on skin\n'}


{'id': 'HP_0000992', 'url': 'http://purl.obolibrary.org/obo/HP_0000992', 'lbl': 'Cutaneous photosensitivity', 'desc': 'label: Cutaneous photosensitivity\ndefinition : An increased sensitivity of the skin to light. Photosensitivity may result in a rash upon exposure to the sun (which is known as photodermatosis). Photosensitivity can be diagnosed by phototests in which light is shone on small areas of skin.\nsynonyms :Photosensitive skin; Photosensitive skin rashes; Photosensitivity; Sensitivity to sunlight; Skin photosensitivity; Sun sensitivity\n'}


{'id': 'HP_0000993', 'url': 'http://purl.obolibrary.org/obo/HP_0000993', 'lbl': 'Molluscoid pseudotumors', 'desc': 'label: Molluscoid pseudotumors\ndefinition : Bluish-grey, spongy nodules associated with scars over pressure points and easily traumatized areas like the elbows and knees.\nsynonyms :Molluscoid pseudotumor\n'}


{'id': 'HP_0000995', 'url': 'http://purl.obolibrary.org/obo/HP_0000995', 'lbl': 'Melanocytic nevus', 'desc': 'label: Melanocytic nevus\ndefinition : A oval and round, colored (usually medium-to dark brown, reddish brown, or flesh colored) lesion. Typically, a melanocytic nevus is less than 6 mm in diameter, but may be much smaller or larger.\nsynonyms :Noncancerous mole; Beauty mark; Melanocytic naevus; Melanocytic nevi; Nevocellular nevi; Pigmented naevi; Pigmented nevi\n'}


{'id': 'HP_0000996', 'url': 'http://purl.obolibrary.org/obo/HP_0000996', 'lbl': 'Facial capillary hemangioma', 'desc': 'label: Facial capillary hemangioma\ndefinition : Hemangioma, a benign tumor of the vascular endothelial cells with small endothelial spaces, occurring in the face.\nsynonyms :\n'}


{'id': 'HP_0000997', 'url': 'http://purl.obolibrary.org/obo/HP_0000997', 'lbl': 'Axillary freckling', 'desc': 'label: Axillary freckling\ndefinition : The presence in the axillary region (armpit) of an increased number of freckles, small circular spots on the skin that are darker than the surrounding skin because of deposits of melanin.\nsynonyms :\n'}


{'id': 'HP_0000998', 'url': 'http://purl.obolibrary.org/obo/HP_0000998', 'lbl': 'Hypertrichosis', 'desc': 'label: Hypertrichosis\ndefinition : Hypertrichosis is increased hair growth that is abnormal in quantity or location.\nsynonyms :Excessive hair growth; Increased hair growth on body\n'}


{'id': 'HP_0000999', 'url': 'http://purl.obolibrary.org/obo/HP_0000999', 'lbl': 'Pyoderma', 'desc': 'label: Pyoderma\ndefinition : Any manifestation of a skin disease associated with the production of pus.\nsynonyms :Pus-filled lesion\n'}


{'id': 'HP_0001000', 'url': 'http://purl.obolibrary.org/obo/HP_0001000', 'lbl': 'Abnormality of skin pigmentation', 'desc': 'label: Abnormality of skin pigmentation\ndefinition : An abnormality of the pigmentation of the skin.\nsynonyms :Abnormal pigmentation; Abnormal skin color; Abnormal skin colour; Abnormal skin pigmentation; Abnormality of pigmentation; Abnormality of skin pigmentation; Pigmentary changes; Pigmentary skin changes; Pigmentation anomaly\n'}


{'id': 'HP_0001001', 'url': 'http://purl.obolibrary.org/obo/HP_0001001', 'lbl': 'Abnormality of subcutaneous fat tissue', 'desc': 'label: Abnormality of subcutaneous fat tissue\ndefinition : \nsynonyms :Abnormality of fatty tissue below the skin\n'}


{'id': 'HP_0001002', 'url': 'http://purl.obolibrary.org/obo/HP_0001002', 'lbl': 'obsolete Decreased subcutaneous fat', 'desc': 'label: obsolete Decreased subcutaneous fat\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001003', 'url': 'http://purl.obolibrary.org/obo/HP_0001003', 'lbl': 'Multiple lentigines', 'desc': 'label: Multiple lentigines\ndefinition : Presence of an unusually high number of lentigines (singular: lentigo), which are flat, tan to brown oval spots.\nsynonyms :Liver spots\n'}


{'id': 'HP_0001004', 'url': 'http://purl.obolibrary.org/obo/HP_0001004', 'lbl': 'Lymphedema', 'desc': 'label: Lymphedema\ndefinition : Localized fluid retention and tissue swelling caused by a compromised lymphatic system.\nsynonyms :Lymphatic obstruction; Lymphoedema; Onset of lymphedema around puberty; Swelling caused by excess lymph fluid under skin\n'}


{'id': 'HP_0001005', 'url': 'http://purl.obolibrary.org/obo/HP_0001005', 'lbl': 'Dermatological manifestations of systemic disorders', 'desc': 'label: Dermatological manifestations of systemic disorders\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001006', 'url': 'http://purl.obolibrary.org/obo/HP_0001006', 'lbl': 'obsolete Hypotrichosis', 'desc': 'label: obsolete Hypotrichosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001007', 'url': 'http://purl.obolibrary.org/obo/HP_0001007', 'lbl': 'Hirsutism', 'desc': 'label: Hirsutism\ndefinition : Abnormally increased hair growth referring to a male pattern of body hair (androgenic hair).\nsynonyms :Excessive hairiness\n'}


{'id': 'HP_0001008', 'url': 'http://purl.obolibrary.org/obo/HP_0001008', 'lbl': 'Accumulation of melanosomes in melanocytes', 'desc': 'label: Accumulation of melanosomes in melanocytes\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001009', 'url': 'http://purl.obolibrary.org/obo/HP_0001009', 'lbl': 'Telangiectasia', 'desc': 'label: Telangiectasia\ndefinition : Telangiectasias refer to small dilated blood vessels located near the surface of the skin or mucous membranes, measuring between 0.5 and 1 millimeter in diameter. Telangiectasia are located especially on the tongue, lips, palate, fingers, face, conjunctiva, trunk, nail beds, and fingertips.\nsynonyms :Telangiectases; Spider veins\n'}


{'id': 'HP_0001010', 'url': 'http://purl.obolibrary.org/obo/HP_0001010', 'lbl': 'Hypopigmentation of the skin', 'desc': 'label: Hypopigmentation of the skin\ndefinition : A reduction of skin color related to a decrease in melanin production and deposition.\nsynonyms :Hypopigmentation; Hypopigmented skin; Patchy lightened skin; Skin hypopigmentation\n'}


{'id': 'HP_0001011', 'url': 'http://purl.obolibrary.org/obo/HP_0001011', 'lbl': 'obsolete Diaphoresis (with pheochromocytoma)', 'desc': 'label: obsolete Diaphoresis (with pheochromocytoma)\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001012', 'url': 'http://purl.obolibrary.org/obo/HP_0001012', 'lbl': 'Multiple lipomas', 'desc': 'label: Multiple lipomas\ndefinition : The presence of multiple lipomas (a type of benign tissue made of fatty tissue).\nsynonyms :Multiple fatty lumps; Lipomas; Lipomatosis\n'}


{'id': 'HP_0001013', 'url': 'http://purl.obolibrary.org/obo/HP_0001013', 'lbl': 'Eruptive xanthomas', 'desc': 'label: Eruptive xanthomas\ndefinition : Eruptive xanthomas are yellow-orange-to-red-brown papules that are often surrounded by an erythematous halo. They appear in crops on the buttocks, extensor surfaces of the extremities, and flexural creases. Acutely, variable amounts of pruritus and pain occur.\nsynonyms :\n'}


{'id': 'HP_0001014', 'url': 'http://purl.obolibrary.org/obo/HP_0001014', 'lbl': 'Angiokeratoma', 'desc': 'label: Angiokeratoma\ndefinition : Angiokeratomas are hyperkeratotic papules that are characterized histologically by superficial ectatic (i.e., dilated) blood vessels with epidermal proliferation. Clinically, angiokeratoma presents as a small, raised, dark-red spot.\nsynonyms :Angiokeratomas\n'}


{'id': 'HP_0001015', 'url': 'http://purl.obolibrary.org/obo/HP_0001015', 'lbl': 'Prominent superficial veins', 'desc': 'label: Prominent superficial veins\ndefinition : A condition in which superficial veins (i.e., veins just under the skin) are more conspicuous or noticable than normal.\nsynonyms :Marked subcutaneous veins; Prominent veins\n'}


{'id': 'HP_0001017', 'url': 'http://purl.obolibrary.org/obo/HP_0001017', 'lbl': 'Anemic pallor', 'desc': 'label: Anemic pallor\ndefinition : A type of pallor that is secondary to the presence of anemia.\nsynonyms :Anaemic pallor\n'}


{'id': 'HP_0001018', 'url': 'http://purl.obolibrary.org/obo/HP_0001018', 'lbl': 'Abnormal palmar dermatoglyphics', 'desc': 'label: Abnormal palmar dermatoglyphics\ndefinition : An abnormality of the dermatoglyphs, i.e., an abnormality of the patterns of ridges of the skin of palm of hand.\nsynonyms :\n'}


{'id': 'HP_0001019', 'url': 'http://purl.obolibrary.org/obo/HP_0001019', 'lbl': 'Erythroderma', 'desc': 'label: Erythroderma\ndefinition : An inflammatory exfoliative dermatosis involving nearly all of the surface of the skin. Erythroderma develops suddenly. A patchy erythema may generalize and spread to affect most of the skin. Scaling may appear in 2-6 days and be accompanied by hot, red, dry skin, malaise, and fever.\nsynonyms :Red scaly skin caused by inflammatory skin disease; Exfoliative dermititis; Generalised erythroderma; Generalised erythrodermia; Generalized erythroderma; Generalized erythrodermia\n'}


{'id': 'HP_0001022', 'url': 'http://purl.obolibrary.org/obo/HP_0001022', 'lbl': 'Albinism', 'desc': 'label: Albinism\ndefinition : An abnormal reduction in the amount of pigmentation (reduced or absent) of skin, hair and eye (iris and retina).\nsynonyms :Achromasia; Albinism\n'}


{'id': 'HP_0001024', 'url': 'http://purl.obolibrary.org/obo/HP_0001024', 'lbl': 'Skin dimple over apex of long bone angulation', 'desc': 'label: Skin dimple over apex of long bone angulation\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001025', 'url': 'http://purl.obolibrary.org/obo/HP_0001025', 'lbl': 'Urticaria', 'desc': 'label: Urticaria\ndefinition : Raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis. Urticaria is intensely pruritic, and blanches completely with pressure.\nsynonyms :Hives\n'}


{'id': 'HP_0001026', 'url': 'http://purl.obolibrary.org/obo/HP_0001026', 'lbl': 'Penetrating foot ulcers', 'desc': 'label: Penetrating foot ulcers\ndefinition : \nsynonyms :Penetrating foot ulcers\n'}


{'id': 'HP_0001027', 'url': 'http://purl.obolibrary.org/obo/HP_0001027', 'lbl': 'Soft, doughy skin', 'desc': 'label: Soft, doughy skin\ndefinition : A skin texture that is unusually soft (and may feel silky), and has a malleable consistency resembling that of dough.\nsynonyms :Soft, doughy skin\n'}


{'id': 'HP_0001028', 'url': 'http://purl.obolibrary.org/obo/HP_0001028', 'lbl': 'Hemangioma', 'desc': 'label: Hemangioma\ndefinition : A hemangioma is a benign tumor characterized by blood-filled spaces lined by benign endothelial cells. A hemangioma characterized by large endothelial spaces (caverns) is called a cavernous hemangioma (in contrast to a hemangioma with small endothelial spaces, which is called capillary hemangioma).\nsynonyms :Strawberry mark; Hemangiomata\n'}


{'id': 'HP_0001029', 'url': 'http://purl.obolibrary.org/obo/HP_0001029', 'lbl': 'Poikiloderma', 'desc': 'label: Poikiloderma\ndefinition : Poikiloderma refers to a patch of skin with (1) reticulated hypopigmentation and hyperpigmentation, (2) wrinkling secondary to epidermal atrophy, and (3) telangiectasias.\nsynonyms :\n'}


{'id': 'HP_0001030', 'url': 'http://purl.obolibrary.org/obo/HP_0001030', 'lbl': 'Fragile skin', 'desc': 'label: Fragile skin\ndefinition : Skin that splits easily with minimal injury.\nsynonyms :Fragile skin; Skin fragility\n'}


{'id': 'HP_0001031', 'url': 'http://purl.obolibrary.org/obo/HP_0001031', 'lbl': 'Subcutaneous lipoma', 'desc': 'label: Subcutaneous lipoma\ndefinition : The presence of subcutaneous lipoma.\nsynonyms :\n'}


{'id': 'HP_0001032', 'url': 'http://purl.obolibrary.org/obo/HP_0001032', 'lbl': 'Absent distal interphalangeal creases', 'desc': 'label: Absent distal interphalangeal creases\ndefinition : Absence of the distal interphalangeal flexion creases of the fingers.\nsynonyms :Absence of skin creases over distal interphalangeal joints; Aplasia of the distal interphalangeal creases; Distal finger flexion creases absent\n'}


{'id': 'HP_0001033', 'url': 'http://purl.obolibrary.org/obo/HP_0001033', 'lbl': 'Facial flushing after alcohol intake', 'desc': 'label: Facial flushing after alcohol intake\ndefinition : \nsynonyms :Facial flushing after alcohol intake\n'}


{'id': 'HP_0001034', 'url': 'http://purl.obolibrary.org/obo/HP_0001034', 'lbl': 'Hypermelanotic macule', 'desc': 'label: Hypermelanotic macule\ndefinition : A hyperpigmented circumscribed area of change in normal skin color without elevation or depression of any size.\nsynonyms :Hyperpigmented macules; Hyperpigmented spots; Hyperpigmented skin patches\n'}


{'id': 'HP_0001036', 'url': 'http://purl.obolibrary.org/obo/HP_0001036', 'lbl': 'Parakeratosis', 'desc': 'label: Parakeratosis\ndefinition : Abnormal formation of the keratinocytes of the epidermis characterized by persistence of nuclei, incomplete formation of keratin, and moistness and swelling of the keratinocytes.\nsynonyms :\n'}


{'id': 'HP_0001038', 'url': 'http://purl.obolibrary.org/obo/HP_0001038', 'lbl': 'Warfarin-induced skin necrosis', 'desc': 'label: Warfarin-induced skin necrosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001039', 'url': 'http://purl.obolibrary.org/obo/HP_0001039', 'lbl': 'Atheroeruptive xanthoma', 'desc': 'label: Atheroeruptive xanthoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001040', 'url': 'http://purl.obolibrary.org/obo/HP_0001040', 'lbl': 'Multiple pterygia', 'desc': 'label: Multiple pterygia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001041', 'url': 'http://purl.obolibrary.org/obo/HP_0001041', 'lbl': 'Facial erythema', 'desc': 'label: Facial erythema\ndefinition : Redness of the skin of the face, caused by hyperemia of the capillaries in the lower layers of the skin.\nsynonyms :Blushed cheeks; Blushing; Red face; Red in the face; Rosacea; Ruddy face\n'}


{'id': 'HP_0001042', 'url': 'http://purl.obolibrary.org/obo/HP_0001042', 'lbl': 'High axial triradius', 'desc': 'label: High axial triradius\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001043', 'url': 'http://purl.obolibrary.org/obo/HP_0001043', 'lbl': 'Prominent scalp veins', 'desc': 'label: Prominent scalp veins\ndefinition : \nsynonyms :Prominent scalp veins\n'}


{'id': 'HP_0001045', 'url': 'http://purl.obolibrary.org/obo/HP_0001045', 'lbl': 'Vitiligo', 'desc': 'label: Vitiligo\ndefinition : \nsynonyms :Blotchy loss of skin color; Blotchy loss of skin colour\n'}


{'id': 'HP_0001046', 'url': 'http://purl.obolibrary.org/obo/HP_0001046', 'lbl': 'Intermittent jaundice', 'desc': 'label: Intermittent jaundice\ndefinition : Jaundice that is sometimes present, sometimes not.\nsynonyms :Intermittent icterus; Intermittent yellow skin; Intermittent yellowing of skin\n'}


{'id': 'HP_0001047', 'url': 'http://purl.obolibrary.org/obo/HP_0001047', 'lbl': 'Atopic dermatitis', 'desc': 'label: Atopic dermatitis\ndefinition : Atopic dermatitis (AD) or atopic eczema is an itchy, inflammatory skin condition with a predilection for the skin flexures. It is characterized by poorly defined erythema with edema, vesicles, and weeping in the acute stage and skin thickening (lichenification) in the chronic stage.\nsynonyms :Atopic dermatitis, chronic; Dermatitis, Atopic; Baby eczema\n'}


{'id': 'HP_0001048', 'url': 'http://purl.obolibrary.org/obo/HP_0001048', 'lbl': 'Cavernous hemangioma', 'desc': 'label: Cavernous hemangioma\ndefinition : The presence of a cavernous hemangioma. A hemangioma characterized by large endothelial spaces (caverns) is called a cavernous hemangioma.\nsynonyms :Cavernous angioma; Cavernous haemangioma; Collection of dilated blood vessels that forms mass\n'}


{'id': 'HP_0001049', 'url': 'http://purl.obolibrary.org/obo/HP_0001049', 'lbl': 'Absent dorsal skin creases over affected joints', 'desc': 'label: Absent dorsal skin creases over affected joints\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001050', 'url': 'http://purl.obolibrary.org/obo/HP_0001050', 'lbl': 'Plethora', 'desc': 'label: Plethora\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0001051', 'url': 'http://purl.obolibrary.org/obo/HP_0001051', 'lbl': 'Seborrheic dermatitis', 'desc': 'label: Seborrheic dermatitis\ndefinition : Seborrheic dermatitis is a form of eczema which is closely related to dandruff. It causes dry or greasy peeling of the scalp, eyebrows, and face, and sometimes trunk.\nsynonyms :Seborrhea; Seborrheic eczema; Dysseborrheic dermatitis\n'}


{'id': 'HP_0001052', 'url': 'http://purl.obolibrary.org/obo/HP_0001052', 'lbl': 'Nevus flammeus', 'desc': 'label: Nevus flammeus\ndefinition : A congenital vascular malformation consisting of superficial and deep dilated capillaries in the skin which produce a reddish to purplish discolouration of the skin.\nsynonyms :Nevus simplex; port-wine stain\n'}


{'id': 'HP_0001053', 'url': 'http://purl.obolibrary.org/obo/HP_0001053', 'lbl': 'Hypopigmented skin patches', 'desc': 'label: Hypopigmented skin patches\ndefinition : \nsynonyms :Patchy loss of skin color; Patchy loss of skin colour\n'}


{'id': 'HP_0001054', 'url': 'http://purl.obolibrary.org/obo/HP_0001054', 'lbl': 'Numerous nevi', 'desc': 'label: Numerous nevi\ndefinition : \nsynonyms :Multiple pigmented nevi; Numerous moles\n'}


{'id': 'HP_0001055', 'url': 'http://purl.obolibrary.org/obo/HP_0001055', 'lbl': 'Erysipelas', 'desc': "label: Erysipelas\ndefinition : Increased susceptibility to erysipelas, as manifested by a medical history of repeated episodes of erysipelas, which is a superficial infection of the skin, typically involving the lymphatic system.\nsynonyms :St. Anthony's Fire\n"}


{'id': 'HP_0001056', 'url': 'http://purl.obolibrary.org/obo/HP_0001056', 'lbl': 'Milia', 'desc': 'label: Milia\ndefinition : Presence of multiple small cysts containing keratin (skin protein) and presenting as tiny pearly-white bumps just under the surface of the skin.\nsynonyms :Milk spot; Millium cyst\n'}


{'id': 'HP_0001057', 'url': 'http://purl.obolibrary.org/obo/HP_0001057', 'lbl': 'Aplasia cutis congenita', 'desc': 'label: Aplasia cutis congenita\ndefinition : A developmental defect resulting in the congenital absence of skin in multiple or solitary non-inflammatory, well-demarcated, oval or circular ulcers with a diameter of about 1 to 2 cm. Aplasia cutis congenita most commonly occurs on the scalp, but may present in the face, trunk, or limbs.\nsynonyms :Congenital scars; Absence of part of skin at birth; Congenital absence of skin; Cutis aplasia\n'}


{'id': 'HP_0001058', 'url': 'http://purl.obolibrary.org/obo/HP_0001058', 'lbl': 'Poor wound healing', 'desc': 'label: Poor wound healing\ndefinition : A reduced ability to heal cutaneous wounds.\nsynonyms :Poor wound healing\n'}


{'id': 'HP_0001059', 'url': 'http://purl.obolibrary.org/obo/HP_0001059', 'lbl': 'Pterygium', 'desc': "label: Pterygium\ndefinition : Pterygia are 'winglike' triangular membranes occurring in the neck, eyes, knees, elbows, ankles or digits.\nsynonyms :Pterygia\n"}


{'id': 'HP_0001060', 'url': 'http://purl.obolibrary.org/obo/HP_0001060', 'lbl': 'Axillary pterygium', 'desc': 'label: Axillary pterygium\ndefinition : Presence of a cutaneous membrane (flap) in the armpit.\nsynonyms :Axillary pterygia\n'}


{'id': 'HP_0001061', 'url': 'http://purl.obolibrary.org/obo/HP_0001061', 'lbl': 'Acne', 'desc': 'label: Acne\ndefinition : A skin condition in which there is an increase in sebum secretion by the pilosebaceous apparatus associated with open comedones (blackheads), closed comedones (whiteheads), and pustular nodules (papules, pustules, and cysts).\nsynonyms :Breaking out; Acne\n'}