{'id': 'HP_0025488', 'url': 'http://purl.obolibrary.org/obo/HP_0025488', 'lbl': 'Detrusor sphincter dyssynergia', 'desc': 'label: Detrusor sphincter dyssynergia\ndefinition : A urodynamic anomaly characterized by bladder outlet obstruction from detrusor muscle contraction with concomitant involuntary urethral sphincter activation.\nsynonyms :\n'}


{'id': 'HP_0025489', 'url': 'http://purl.obolibrary.org/obo/HP_0025489', 'lbl': 'Bladder duplication', 'desc': 'label: Bladder duplication\ndefinition : A congenital anomaly characterized by the presence of two bladders.\nsynonyms :\n'}


{'id': 'HP_0025490', 'url': 'http://purl.obolibrary.org/obo/HP_0025490', 'lbl': 'Myocardial bridging', 'desc': 'label: Myocardial bridging\ndefinition : A congenital variant of a coronary artery in which a portion of an epicardial coronary artery (most frequently the middle segment of the left anterior descending artery) takes an intramuscular course.\nsynonyms :Intramyocardial coronary artery course\n'}


{'id': 'HP_0025491', 'url': 'http://purl.obolibrary.org/obo/HP_0025491', 'lbl': 'Venous stenosis', 'desc': 'label: Venous stenosis\ndefinition : Narrowing of a vein due to intimal hyperplasia and fibrosis.\nsynonyms :\n'}


{'id': 'HP_0025492', 'url': 'http://purl.obolibrary.org/obo/HP_0025492', 'lbl': 'Microcoria', 'desc': 'label: Microcoria\ndefinition : A small pupil (typically diameter less than 2 mm) that dilates poorly or not at all in response to topically administered mydriatic drugs.\nsynonyms :\n'}


{'id': 'HP_0025493', 'url': 'http://purl.obolibrary.org/obo/HP_0025493', 'lbl': 'Palmoplantar erythema', 'desc': 'label: Palmoplantar erythema\ndefinition : Redness of the skin of the palm of the hand and the sole of the foot caused by hyperemia of the capillaries in the lower layers of the skin.\nsynonyms :\n'}


{'id': 'HP_0025494', 'url': 'http://purl.obolibrary.org/obo/HP_0025494', 'lbl': 'Coated aorta', 'desc': 'label: Coated aorta\ndefinition : Regular circumferential periaortic fibrosis involving the whole aorta and leading to a coated aorta appearance on computed tomography scans\nsynonyms :\n'}


{'id': 'HP_0025495', 'url': 'http://purl.obolibrary.org/obo/HP_0025495', 'lbl': 'Descending aorta hypoplasia', 'desc': 'label: Descending aorta hypoplasia\ndefinition : Significant luminal narrowing of a long segment of the descending aorta.\nsynonyms :\n'}


{'id': 'HP_0025496', 'url': 'http://purl.obolibrary.org/obo/HP_0025496', 'lbl': 'Abnormal coronary artery physiology', 'desc': 'label: Abnormal coronary artery physiology\ndefinition : Any anomaly of the function of a coronary artery.\nsynonyms :\n'}


{'id': 'HP_0025497', 'url': 'http://purl.obolibrary.org/obo/HP_0025497', 'lbl': 'Coronary artery spasm', 'desc': 'label: Coronary artery spasm\ndefinition : A brief and sudden narrowing of a coronary artery.\nsynonyms :Coronary artery vasospasm\n'}


{'id': 'HP_0025498', 'url': 'http://purl.obolibrary.org/obo/HP_0025498', 'lbl': 'Aceruloplasminemia', 'desc': 'label: Aceruloplasminemia\ndefinition : Absence of ceruloplasmin in the blood.\nsynonyms :Aceruloplasminaemia\n'}


{'id': 'HP_0025499', 'url': 'http://purl.obolibrary.org/obo/HP_0025499', 'lbl': 'Class I obesity', 'desc': 'label: Class I obesity\ndefinition : Obesity with a body mass index of 30 to 34.9 kg per square meter.\nsynonyms :Obesity grade 1\n'}


{'id': 'HP_0025500', 'url': 'http://purl.obolibrary.org/obo/HP_0025500', 'lbl': 'Class II obesity', 'desc': 'label: Class II obesity\ndefinition : Obesity with a body mass index of 35 to 39.9 kg per square meter.\nsynonyms :Obesity grade 2\n'}


{'id': 'HP_0025501', 'url': 'http://purl.obolibrary.org/obo/HP_0025501', 'lbl': 'Class III obesity', 'desc': 'label: Class III obesity\ndefinition : Obesity with a body mass index of 40 kg per square meter or higher.\nsynonyms :Obesity grade 3\n'}


{'id': 'HP_0025502', 'url': 'http://purl.obolibrary.org/obo/HP_0025502', 'lbl': 'Overweight', 'desc': 'label: Overweight\ndefinition : Increased body weight with a body mass index of 25-29.9 kg per square meter.\nsynonyms :\n'}


{'id': 'HP_0025503', 'url': 'http://purl.obolibrary.org/obo/HP_0025503', 'lbl': 'Anomalous coronary artery arising from the opposite sinus', 'desc': 'label: Anomalous coronary artery arising from the opposite sinus\ndefinition : Origin of the right coronary artery (RCA) from the left sinus of Valsalva or of the left main (LM) or left anterior descending (LAD) coronary artery from the right sinus of Valsalva.\nsynonyms :\n'}


{'id': 'HP_0025505', 'url': 'http://purl.obolibrary.org/obo/HP_0025505', 'lbl': 'Anomalous origin of the circumflex artery from the right sinus of Valsalva', 'desc': 'label: Anomalous origin of the circumflex artery from the right sinus of Valsalva\ndefinition : The circumflex coronary artery originates from the right aortic sinus of Valsalva.\nsynonyms :\n'}


{'id': 'HP_0025506', 'url': 'http://purl.obolibrary.org/obo/HP_0025506', 'lbl': 'Coronary artery sandwich anomaly', 'desc': 'label: Coronary artery sandwich anomaly\ndefinition : Origin of the right coronary artery (RCA) from the left sinus of Valsalva or of the left main (LM) or left anterior descending (LAD) coronary artery from the right sinus of Valsalva, with the additional feature that the artery passes between the two great arteries. This carries a risk of the artery being compressed by these two vessels,\nsynonyms :Anomalous coronary artery with aortic origin and course between the great arteries\n'}


{'id': 'HP_0025507', 'url': 'http://purl.obolibrary.org/obo/HP_0025507', 'lbl': 'Yellow papule', 'desc': 'label: Yellow papule\ndefinition : A papule with yellow color.\nsynonyms :Yellow-orange papule\n'}


{'id': 'HP_0025508', 'url': 'http://purl.obolibrary.org/obo/HP_0025508', 'lbl': "Gottron's papules", 'desc': "label: Gottron's papules\ndefinition : Violaceous papules overlying the dorsal and lateral aspects of the metacarpophalangeal and proximal interphalangeal joints.\nsynonyms :Gottron papules\n"}


{'id': 'HP_0025509', 'url': 'http://purl.obolibrary.org/obo/HP_0025509', 'lbl': 'Piezogenic pedal papules', 'desc': 'label: Piezogenic pedal papules\ndefinition : Flesh-colored or yellowish papules, 2 mm or larger, that are responses to internal mechanical pressure and weakness in the connective tissue in the dermis, appear commonly over the medial aspect of the heel, but in some cases on the wrists. They are thought to represent herniations of adipose tissue through the plantar fascia retinaculum.\nsynonyms :\n'}


{'id': 'HP_0025510', 'url': 'http://purl.obolibrary.org/obo/HP_0025510', 'lbl': 'Nevus spilus', 'desc': 'label: Nevus spilus\ndefinition : A tan, regularly bordered patch with darker macules within the lesion.\nsynonyms :Speckled lentiginous Nevus\n'}


{'id': 'HP_0025511', 'url': 'http://purl.obolibrary.org/obo/HP_0025511', 'lbl': 'Nevus sebaceus', 'desc': 'label: Nevus sebaceus\ndefinition : A solitary yellow-orange slightly raised plaque typically on scalp or face. The plaque typically thickens and becomes more verrucous or pebbly during childhood.\nsynonyms :\n'}


{'id': 'HP_0025512', 'url': 'http://purl.obolibrary.org/obo/HP_0025512', 'lbl': 'Skin-colored papule', 'desc': 'label: Skin-colored papule\ndefinition : A papule with the same color as the surrounding skin.\nsynonyms :Flesh-colored papule\n'}


{'id': 'HP_0025513', 'url': 'http://purl.obolibrary.org/obo/HP_0025513', 'lbl': 'Scleral rupture', 'desc': 'label: Scleral rupture\ndefinition : Breakage of the sclera.\nsynonyms :\n'}


{'id': 'HP_0025514', 'url': 'http://purl.obolibrary.org/obo/HP_0025514', 'lbl': 'Morning glory anomaly', 'desc': 'label: Morning glory anomaly\ndefinition : An abnormality of the optic nerve in which the optic nerve is large and funneled and displays a conical excavation of the optic disc. The optic disc appears dysplastic.\nsynonyms :Morning glory disc anomaly; Morning glory optic disc\n'}


{'id': 'HP_0025515', 'url': 'http://purl.obolibrary.org/obo/HP_0025515', 'lbl': 'Delayed thelarche', 'desc': 'label: Delayed thelarche\ndefinition : Later than normal development of the breasts.\nsynonyms :\n'}


{'id': 'HP_0025516', 'url': 'http://purl.obolibrary.org/obo/HP_0025516', 'lbl': 'Coronary-pulmonary artery fistula', 'desc': 'label: Coronary-pulmonary artery fistula\ndefinition : A congenital malformation with abnormal connection between one of the coronary arteries and the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0025517', 'url': 'http://purl.obolibrary.org/obo/HP_0025517', 'lbl': 'Hypoplastic hippocampus', 'desc': 'label: Hypoplastic hippocampus\ndefinition : Underdevelopment of the hippocampus.\nsynonyms :Small hippocampus; Underdeveloped hippocampus\n'}


{'id': 'HP_0025518', 'url': 'http://purl.obolibrary.org/obo/HP_0025518', 'lbl': 'Visual gaze preference', 'desc': 'label: Visual gaze preference\ndefinition : An abnormality of gaze that can be observed following an acute supranuclear cerebral lesion (e.g., stroke) that is characterized by an acute inability to direct gaze contralateral to the side of the lesion and is accompanied by a tendency for tonic deviation of the eyes toward the side of the lesion.\nsynonyms :\n'}


{'id': 'HP_0025519', 'url': 'http://purl.obolibrary.org/obo/HP_0025519', 'lbl': 'Multiple biliary hamartomas', 'desc': 'label: Multiple biliary hamartomas\ndefinition : Multiple biliary hamartomas are a rare clinicopathologic entity, consisting of small (less than 1.5cm), usually multiple and nodular cystic lesions in the liver.\nsynonyms :Multiple bile duct hamartomas; Von Meyenburg complexes; Biliary hamartoma\n'}


{'id': 'HP_0025520', 'url': 'http://purl.obolibrary.org/obo/HP_0025520', 'lbl': 'Calcinosis cutis', 'desc': 'label: Calcinosis cutis\ndefinition : Deposition of calcium in the skin.\nsynonyms :Cutaneous calcification\n'}


{'id': 'HP_0025521', 'url': 'http://purl.obolibrary.org/obo/HP_0025521', 'lbl': 'Increased body fat percentage', 'desc': 'label: Increased body fat percentage\ndefinition : The percentage of fat as a part of total body weight above the norm, usually defined as 32% for females and 25% for males.\nsynonyms :\n'}


{'id': 'HP_0025522', 'url': 'http://purl.obolibrary.org/obo/HP_0025522', 'lbl': 'Elongated chordae tendinae of the mitral valve', 'desc': 'label: Elongated chordae tendinae of the mitral valve\ndefinition : Abnormal increased in length of the chordae tendinae of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0025523', 'url': 'http://purl.obolibrary.org/obo/HP_0025523', 'lbl': 'Abnormal morphology of the chordae tendinae of the mitral valve', 'desc': 'label: Abnormal morphology of the chordae tendinae of the mitral valve\ndefinition : A structural anomaly of the chordae tendinae of the mitral valve, whose main function is to transmit the contraction and relaxation of the papillary muscles during the cardiac cycle, thus ensuring the closing of the leaflets of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0025524', 'url': 'http://purl.obolibrary.org/obo/HP_0025524', 'lbl': 'Palmoplantar scaling skin', 'desc': 'label: Palmoplantar scaling skin\ndefinition : Loss of the outer layer of the epidermis in large, scale-like flakes localized to the palm of the hand and the sole of the foot.\nsynonyms :Palmoplantar psoriasis\n'}


{'id': 'HP_0025525', 'url': 'http://purl.obolibrary.org/obo/HP_0025525', 'lbl': 'Scaling skin on fingertip', 'desc': 'label: Scaling skin on fingertip\ndefinition : Loss of the outer layer of the epidermis in large, scale-like flakes localized to one or more fingertips.\nsynonyms :\n'}


{'id': 'HP_0025526', 'url': 'http://purl.obolibrary.org/obo/HP_0025526', 'lbl': 'Psoriasiform lesion', 'desc': 'label: Psoriasiform lesion\ndefinition : A skin lesions that resembles the lesions observed in psoriasis, viz., an erythematous plaque covered by fine silvery scales. Psoriasiform lesions can be observed in psoriasis as well as in other conditions including allergic contact dermatitis, seborrhoeic dermatitis, Atopic dermatitis, pityriasis rubra, and lichen simplex chronicus.\nsynonyms :Psoriatic-like lesion; Erythemato-squamous plaque; Erythematosquamous plaque\n'}


{'id': 'HP_0025527', 'url': 'http://purl.obolibrary.org/obo/HP_0025527', 'lbl': 'Serpiginous cutaneous lesion', 'desc': 'label: Serpiginous cutaneous lesion\ndefinition : A skin lesion with a snake- or serpent-like distribution.\nsynonyms :Serpiginous eruption\n'}


{'id': 'HP_0025528', 'url': 'http://purl.obolibrary.org/obo/HP_0025528', 'lbl': 'Annular cutaneous lesion', 'desc': 'label: Annular cutaneous lesion\ndefinition : A lesion of the skin with a ring-like distribution.\nsynonyms :\n'}


{'id': 'HP_0025529', 'url': 'http://purl.obolibrary.org/obo/HP_0025529', 'lbl': 'Hyperpigmented nodule', 'desc': 'label: Hyperpigmented nodule\ndefinition : A nodule of the skin that exhibits an increased amount of pigmentation.\nsynonyms :\n'}


{'id': 'HP_0025530', 'url': 'http://purl.obolibrary.org/obo/HP_0025530', 'lbl': 'Xanthomas of the palmar creases', 'desc': 'label: Xanthomas of the palmar creases\ndefinition : The presence of multiple xanthomas (xanthomata) in the skin distributed in the creases of the palm of the hand. Xanthomas are yellowish, firm, lipid-laden nodules in the skin.\nsynonyms :Xanthoma palmare striatum; Xanthoma striatum palmare\n'}


{'id': 'HP_0025531', 'url': 'http://purl.obolibrary.org/obo/HP_0025531', 'lbl': 'Harlequin phenomenon', 'desc': 'label: Harlequin phenomenon\ndefinition : The Harlequin phenomenon consists of a sudden change in skin colour, resulting in two different body colours, one on each half of the body.\nsynonyms :\n'}


{'id': 'HP_0025532', 'url': 'http://purl.obolibrary.org/obo/HP_0025532', 'lbl': 'Positive pathergy test', 'desc': 'label: Positive pathergy test\ndefinition : With the pathergy test, a small, sterile needle is inserted into the skin of the forearm. The site of injectionis circuled and observed after one and two days. If a small red bump or pustule at the site of needle insertion occurs, the pathergy test is considered to have a positive (abnormal) result.\nsynonyms :\n'}


{'id': 'HP_0025533', 'url': 'http://purl.obolibrary.org/obo/HP_0025533', 'lbl': "Peau d'orange", 'desc': "label: Peau d'orange\ndefinition : \nsynonyms :\n"}


{'id': 'HP_0025534', 'url': 'http://purl.obolibrary.org/obo/HP_0025534', 'lbl': 'Ocular melanocytosis', 'desc': 'label: Ocular melanocytosis\ndefinition : A congenital lesion of the sclera characterized by unilateral patchy but extensive slate-gray or bluish discoloration of the sclera . The conjunctiva are spared.\nsynonyms :Melanosis oculi; Ocular melanosis\n'}


{'id': 'HP_0025535', 'url': 'http://purl.obolibrary.org/obo/HP_0025535', 'lbl': 'Shawl sign', 'desc': 'label: Shawl sign\ndefinition : Erythematous, poikilodermatous macules distributed in a shawl pattern over the shoulders, arms and upper back.\nsynonyms :\n'}


{'id': 'HP_0025536', 'url': 'http://purl.obolibrary.org/obo/HP_0025536', 'lbl': 'V-sign', 'desc': 'label: V-sign\ndefinition : Erythematous, poikilodermatous macules distributed in a V-shaped distribution over the anterior neck and chest.\nsynonyms :\n'}


{'id': 'HP_0025537', 'url': 'http://purl.obolibrary.org/obo/HP_0025537', 'lbl': 'Plantar edema', 'desc': 'label: Plantar edema\ndefinition : An abnormal accumulation of fluid beneath the skin on sole of the foot.\nsynonyms :Plantar oedema\n'}


{'id': 'HP_0025538', 'url': 'http://purl.obolibrary.org/obo/HP_0025538', 'lbl': 'Palmar edema', 'desc': 'label: Palmar edema\ndefinition : An abnormal accumulation of fluid beneath the skin on the palm of the hand.\nsynonyms :Palmar oedema\n'}


{'id': 'HP_0025539', 'url': 'http://purl.obolibrary.org/obo/HP_0025539', 'lbl': 'Abnormal B cell subset distribution', 'desc': 'label: Abnormal B cell subset distribution\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025540', 'url': 'http://purl.obolibrary.org/obo/HP_0025540', 'lbl': 'Abnormal T cell subset distribution', 'desc': 'label: Abnormal T cell subset distribution\ndefinition : Any abnormality in the proportion T cells subsets relative to the total number of T cells.\nsynonyms :\n'}


{'id': 'HP_0025541', 'url': 'http://purl.obolibrary.org/obo/HP_0025541', 'lbl': 'obsolete Decreased activity of complement receptor', 'desc': 'label: obsolete Decreased activity of complement receptor\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025546', 'url': 'http://purl.obolibrary.org/obo/HP_0025546', 'lbl': 'Abnormal mean corpuscular hemoglobin concentration', 'desc': 'label: Abnormal mean corpuscular hemoglobin concentration\ndefinition : A deviation from the normal range of the average amount of hemoglobin per red blood cell (27 to 31 picograms/cell). A reduced mean corpuscular hemoglobin (MCH) may indicate a hypochromic anemia, but the MCH may be normal if both the total hemoglobin and the red blood cell count are reduced.\nsynonyms :Abnormal MCH; Abnormal MCHC; Abnormal mean corpuscular Hb concentration; Abnormal mean corpuscular haemoglobin; Abnormal mean corpuscular haemoglobin concentration\n'}


{'id': 'HP_0025547', 'url': 'http://purl.obolibrary.org/obo/HP_0025547', 'lbl': 'Decreased mean corpuscular hemoglobin concentration', 'desc': 'label: Decreased mean corpuscular hemoglobin concentration\ndefinition : A reduction from the normal range of the average amount of hemoglobin per red blood cell (27 to 31 picograms/cell). A reduced mean corpuscular hemoglobin (MCH) may indicate a hypochromic anemia, but the MCH may be normal if both the total hemoglobin and the red blood cell count are reduced.\nsynonyms :Decreased MCH; Decreased MCHC; Decreased mean corpuscular Hb concentration; Decreased mean corpuscular haemoglobin; Decreased mean corpuscular haemoglobin concentration\n'}


{'id': 'HP_0025548', 'url': 'http://purl.obolibrary.org/obo/HP_0025548', 'lbl': 'Increased mean corpuscular hemoglobin concentration', 'desc': 'label: Increased mean corpuscular hemoglobin concentration\ndefinition : An elevation over the normal range of the average amount of hemoglobin per red blood cell (27 to 31 picograms/cell).\nsynonyms :Increased MCH; Increased MCHC; Increased mean corpuscular Hb concentration; Increased mean corpuscular haemoglobin; Increased mean corpuscular haemoglobin concentration\n'}


{'id': 'HP_0025549', 'url': 'http://purl.obolibrary.org/obo/HP_0025549', 'lbl': 'Eccentric visual fixation', 'desc': 'label: Eccentric visual fixation\ndefinition : A uniocular condition in which there is fixation of an object by a point other than the fovea. This point adopts the principal visual direction. The degree of the eccentric fixation is defined by its distance from the fovea in degrees.\nsynonyms :Eccentric fixation\n'}


{'id': 'HP_0025550', 'url': 'http://purl.obolibrary.org/obo/HP_0025550', 'lbl': 'Elevated circulating ribitol concentration', 'desc': 'label: Elevated circulating ribitol concentration\ndefinition : An increase above the normal concentration of ribitol in the blood.\nsynonyms :Increased level of ribitol in serum\n'}


{'id': 'HP_0025551', 'url': 'http://purl.obolibrary.org/obo/HP_0025551', 'lbl': 'Optic nerve misrouting', 'desc': 'label: Optic nerve misrouting\ndefinition : Abnormal decussation of the visual pathways, typically identified using visual evoked potentials (VEP) (asymmetrical distribution of the VEP over the posterior scalp).\nsynonyms :Optic pathway misrouting; Visual pathway misrouting\n'}


{'id': 'HP_0025552', 'url': 'http://purl.obolibrary.org/obo/HP_0025552', 'lbl': 'Periorbital purpura', 'desc': 'label: Periorbital purpura\ndefinition : Multiple red/purple spots on the skin that surrounds the eyes that do not blanch (whiten) upon pressure. Purpura is caused by subcutaneous bleeding.\nsynonyms :\n'}


{'id': 'HP_0025553', 'url': 'http://purl.obolibrary.org/obo/HP_0025553', 'lbl': 'Periorbital ecchymosis with tarsal plate sparing', 'desc': 'label: Periorbital ecchymosis with tarsal plate sparing\ndefinition : Subcutaneous bleeding with a diameter greater than 1 cm (ecchymosis). The bleeding does not extend into the tarsal plate (the comparatively thick, elongated plates of dense connective tissue within the eyelid) due to an anatomic structure called the orbital septum, which limits extravasation of blood beyond the tarsal plate.\nsynonyms :Raccoon eyes\n'}


{'id': 'HP_0025554', 'url': 'http://purl.obolibrary.org/obo/HP_0025554', 'lbl': 'Yellow nodule', 'desc': 'label: Yellow nodule\ndefinition : A type of skin nodule (a lesions that is greater than either 10mm in both width and depth, and most frequently centered in the dermis or subcutaneous fat) with a yellowish coloration (that reflects a high lipid content of the lesion).\nsynonyms :\n'}


{'id': 'HP_0025555', 'url': 'http://purl.obolibrary.org/obo/HP_0025555', 'lbl': 'Periungual teleangiectasia', 'desc': 'label: Periungual teleangiectasia\ndefinition : Telangiectasia (small dilated blood vessels) located near to the fingernails or toenails.\nsynonyms :\n'}


{'id': 'HP_0025558', 'url': 'http://purl.obolibrary.org/obo/HP_0025558', 'lbl': 'Lamellar cataract with riders', 'desc': 'label: Lamellar cataract with riders\ndefinition : Lamellar cataracts with associated linear lens opacities radially extending towards the periphery of the lens.\nsynonyms :\n'}


{'id': 'HP_0025559', 'url': 'http://purl.obolibrary.org/obo/HP_0025559', 'lbl': 'Coronary cataract', 'desc': 'label: Coronary cataract\ndefinition : A type of cataract characterised by club-shaped and dot opacities distributed radially in the deep cortex. These lens opacities surround the nucleus in an appearance that is though to resemble a crown.\nsynonyms :\n'}


{'id': 'HP_0025560', 'url': 'http://purl.obolibrary.org/obo/HP_0025560', 'lbl': 'Anterior chamber cells', 'desc': 'label: Anterior chamber cells\ndefinition : Tiny deposits corresponding to cells floating in the anterior chamber of the eye. This appearance is typically associated with intraocular inflammation leading to breakdown of the blood-aqueous barrier and resulting in an increase in the number of cells and in the aqueous humor. Grading (SUN Working Group) is performed by estimating the number of cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025561', 'url': 'http://purl.obolibrary.org/obo/HP_0025561', 'lbl': 'Anterior chamber cells grade 1+', 'desc': 'label: Anterior chamber cells grade 1+\ndefinition : Anterior chamber cells with 6-15 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025562', 'url': 'http://purl.obolibrary.org/obo/HP_0025562', 'lbl': 'Anterior chamber cells grade 0.5+', 'desc': 'label: Anterior chamber cells grade 0.5+\ndefinition : Anterior chamber cells with 1-5 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025563', 'url': 'http://purl.obolibrary.org/obo/HP_0025563', 'lbl': 'Anterior chamber cells grade 0', 'desc': 'label: Anterior chamber cells grade 0\ndefinition : Anterior chamber cells with less than one cell in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025564', 'url': 'http://purl.obolibrary.org/obo/HP_0025564', 'lbl': 'Anterior chamber cells grade 2+', 'desc': 'label: Anterior chamber cells grade 2+\ndefinition : Anterior chamber cells with 16-25 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025565', 'url': 'http://purl.obolibrary.org/obo/HP_0025565', 'lbl': 'Anterior chamber cells grade 3+', 'desc': 'label: Anterior chamber cells grade 3+\ndefinition : Anterior chamber cells with 26-50 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025566', 'url': 'http://purl.obolibrary.org/obo/HP_0025566', 'lbl': 'Anterior chamber cells grade 4+', 'desc': 'label: Anterior chamber cells grade 4+\ndefinition : Anterior chamber cells with more than 50 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp.\nsynonyms :\n'}


{'id': 'HP_0025567', 'url': 'http://purl.obolibrary.org/obo/HP_0025567', 'lbl': 'Central serous chorioretinopathy', 'desc': 'label: Central serous chorioretinopathy\ndefinition : An anomaly of the retina with serous detachment of the neurosensory retina secondary to one or more focal lesions of the retinal pigment epithelium (RPE), and associated with blurred vision, usually in one eye only and perceived typically by the patient as a dark spot in the centre of the visual field with associated micropsia and metamorphopsia. Normal vision often recurs spontaneously within a few months.\nsynonyms :\n'}


{'id': 'HP_0025568', 'url': 'http://purl.obolibrary.org/obo/HP_0025568', 'lbl': 'Abnormal morphology of the choroidal vasculature', 'desc': 'label: Abnormal morphology of the choroidal vasculature\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025569', 'url': 'http://purl.obolibrary.org/obo/HP_0025569', 'lbl': 'Polypoidal choroidal vasculopathy', 'desc': 'label: Polypoidal choroidal vasculopathy\ndefinition : The presence of aneurysmal polypoidal lesions in the choroidal vasculature. The aneurysmal dilatations, also known as polyps, may be found at subfoveal, juxtafoveal, extrafoveal, peripapillary or even peripheral regions. These polypoidal dilatations may be visible as reddish-orange subretinal nodules during ophthalmoscopic examination. The polypoidal lesions are best detected on indocyanine green angiography (ICGA) and might be associated with a branching vascular network (BVN) of neovascularization.\nsynonyms :\n'}


{'id': 'HP_0025570', 'url': 'http://purl.obolibrary.org/obo/HP_0025570', 'lbl': 'Choroidal vascular hyperpermeability', 'desc': 'label: Choroidal vascular hyperpermeability\ndefinition : Increased tendency of choiroidal blood vessels to allow fluids to leak characterized by multifocal choroidal hyperfluorescence on indocyanine green angiography (ICGA).\nsynonyms :Choroidal hyperpermeability\n'}


{'id': 'HP_0025571', 'url': 'http://purl.obolibrary.org/obo/HP_0025571', 'lbl': 'Christmas tree cataract', 'desc': 'label: Christmas tree cataract\ndefinition : A type of cataract that shows a spectacular display of multiple colours that glitters with the change of incident light like an illuminated Christmas tree.\nsynonyms :\n'}


{'id': 'HP_0025572', 'url': 'http://purl.obolibrary.org/obo/HP_0025572', 'lbl': 'Punctal stenosis', 'desc': 'label: Punctal stenosis\ndefinition : Punctal stenosis is a condition in which the external opening of the lacrimal canaliculus is narrowed or occluded.\nsynonyms :Lacrimal punctum stenosis; Stenosis of the lacrimal punctum\n'}


{'id': 'HP_0025573', 'url': 'http://purl.obolibrary.org/obo/HP_0025573', 'lbl': 'Mild myopia', 'desc': 'label: Mild myopia\ndefinition : A mild form of myopia with up to -3.00 diopters.\nsynonyms :\n'}


{'id': 'HP_0025574', 'url': 'http://purl.obolibrary.org/obo/HP_0025574', 'lbl': 'Macular hemorrhage', 'desc': 'label: Macular hemorrhage\ndefinition : Bleeding occurring within the macula lutea of the retina.\nsynonyms :Macular haemorrhage\n'}


{'id': 'HP_0025575', 'url': 'http://purl.obolibrary.org/obo/HP_0025575', 'lbl': 'Abnormal superior vena cava morphology', 'desc': 'label: Abnormal superior vena cava morphology\ndefinition : Any structural anomaly of the principal vein draining blood from the upper portion of the body and delivering it to the right ventricle of the heart.\nsynonyms :\n'}


{'id': 'HP_0025576', 'url': 'http://purl.obolibrary.org/obo/HP_0025576', 'lbl': 'Abnormal inferior vena cava morphology', 'desc': 'label: Abnormal inferior vena cava morphology\ndefinition : Any structural anomaly of the principal vein draining blood from the lower portion of the body.\nsynonyms :\n'}


{'id': 'HP_0025578', 'url': 'http://purl.obolibrary.org/obo/HP_0025578', 'lbl': 'Aortic valve prolapse', 'desc': 'label: Aortic valve prolapse\ndefinition : Aortic valve prolapse can be diagnosed when either or both of the right or non-coronary aortic valve cusps (seen in the cross sectional echocardiographic long axis view) show backward bowing towards the left ventricle beyond a line joining the points of attachment of the aortic valve leaflets to the annulus.\nsynonyms :\n'}


{'id': 'HP_0025579', 'url': 'http://purl.obolibrary.org/obo/HP_0025579', 'lbl': 'Abnormal left atrium morphology', 'desc': 'label: Abnormal left atrium morphology\ndefinition : Any structural abnormality of the left atrium.\nsynonyms :\n'}


{'id': 'HP_0025580', 'url': 'http://purl.obolibrary.org/obo/HP_0025580', 'lbl': 'Abnormal right atrium morphology', 'desc': 'label: Abnormal right atrium morphology\ndefinition : Any structural abnormality of the right atrium.\nsynonyms :\n'}


{'id': 'HP_0025581', 'url': 'http://purl.obolibrary.org/obo/HP_0025581', 'lbl': 'Foveal hemorrhage', 'desc': 'label: Foveal hemorrhage\ndefinition : Bleeding occurring within the fovea.\nsynonyms :Foveal haemorrhage\n'}


{'id': 'HP_0025582', 'url': 'http://purl.obolibrary.org/obo/HP_0025582', 'lbl': 'Submacular hemorrhage', 'desc': 'label: Submacular hemorrhage\ndefinition : Bleeding between the neurosensory retina and the retinal pigment epithelium (RPE) arising from the choroidal or retinal circulation.\nsynonyms :Sub-macular haemorrhage; Sub-macular hemorrhage; Submacular haemorrhage\n'}


{'id': 'HP_0025583', 'url': 'http://purl.obolibrary.org/obo/HP_0025583', 'lbl': 'Tapetal-like fundal reflex', 'desc': "label: Tapetal-like fundal reflex\ndefinition : Golden, scintillating, particulate reflection noted on fundus examination (typically in the macula and sparing the fovea). The term tapetal is used to describe this 'metallic' sheen appearance as it is thought to be similar to the 'tapetal' reflex seen in the eyes of certain animals.\nsynonyms :\n"}


{'id': 'HP_0025584', 'url': 'http://purl.obolibrary.org/obo/HP_0025584', 'lbl': 'Hypotropia', 'desc': 'label: Hypotropia\ndefinition : A form of manifest strabismus (heterotropia) in which one eye is deviated downwards when both eyes are open.\nsynonyms :\n'}


{'id': 'HP_0025585', 'url': 'http://purl.obolibrary.org/obo/HP_0025585', 'lbl': 'Hyperphoria', 'desc': 'label: Hyperphoria\ndefinition : Tendency for the visual axis of one eye to be higher than that of the other.\nsynonyms :\n'}


{'id': 'HP_0025586', 'url': 'http://purl.obolibrary.org/obo/HP_0025586', 'lbl': 'Hypertropia', 'desc': 'label: Hypertropia\ndefinition : A type of strabismus characterized by permanent upward deviation of the visual axis of one eye.\nsynonyms :\n'}


{'id': 'HP_0025587', 'url': 'http://purl.obolibrary.org/obo/HP_0025587', 'lbl': 'Hyperdeviation', 'desc': 'label: Hyperdeviation\ndefinition : A type of strabismus in which the visual axis of one eye is higher than that of the other.\nsynonyms :\n'}


{'id': 'HP_0025588', 'url': 'http://purl.obolibrary.org/obo/HP_0025588', 'lbl': 'Hypodeviation', 'desc': 'label: Hypodeviation\ndefinition : A type of strabismus in which the visual axis of one eye is lower than that of the other.\nsynonyms :\n'}


{'id': 'HP_0025589', 'url': 'http://purl.obolibrary.org/obo/HP_0025589', 'lbl': 'Cyclodeviation', 'desc': 'label: Cyclodeviation\ndefinition : Cyclodeviation is defined as the rotation of an eyeball along the anteroposterior axis and cyclotropia as a misalignment of cyclodeviation between the two eyes.\nsynonyms :\n'}


{'id': 'HP_0025590', 'url': 'http://purl.obolibrary.org/obo/HP_0025590', 'lbl': 'Abnormal extraocular muscle physiology', 'desc': 'label: Abnormal extraocular muscle physiology\ndefinition : A functional anomaly of the muscles of the eye.\nsynonyms :\n'}


{'id': 'HP_0025591', 'url': 'http://purl.obolibrary.org/obo/HP_0025591', 'lbl': 'Abnormal superior oblique muscle physiology', 'desc': 'label: Abnormal superior oblique muscle physiology\ndefinition : A functional anomaly of the superior oblique muscle, a fusiform muscle that originates in the upper, medial side of the orbit. The superior oblique muscle abducts, depresses and internally rotates the eye, and is the only extraocular muscle innervated by the fourth cranial nerve.\nsynonyms :\n'}


{'id': 'HP_0025592', 'url': 'http://purl.obolibrary.org/obo/HP_0025592', 'lbl': 'Superior oblique muscle weakness', 'desc': 'label: Superior oblique muscle weakness\ndefinition : Decreased strength of the superior oblique muscle.\nsynonyms :Superior oblique palsy\n'}


{'id': 'HP_0025593', 'url': 'http://purl.obolibrary.org/obo/HP_0025593', 'lbl': 'Superior oblique muscle restriction', 'desc': 'label: Superior oblique muscle restriction\ndefinition : Mechanical limitation of the range of movement of the superior oblique muscle.\nsynonyms :\n'}


{'id': 'HP_0025594', 'url': 'http://purl.obolibrary.org/obo/HP_0025594', 'lbl': 'Superior oblique muscle overaction', 'desc': 'label: Superior oblique muscle overaction\ndefinition : An ocular motility abnormality characterized by an overacting superior oblique muscle resulting to vertical incomitance of the eyes in lateral gaze. On examination, this is commonly seen as a downshoot of the adducting eye occuring when gaze is directed into the field of action of the inferior oblique muscle, producing a greater downward excursion of the adducted eye than of the abducted eye.\nsynonyms :\n'}


{'id': 'HP_0025595', 'url': 'http://purl.obolibrary.org/obo/HP_0025595', 'lbl': 'Superior oblique muscle underaction', 'desc': 'label: Superior oblique muscle underaction\ndefinition : Reduced ocular movement of the superior oblique muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :Under-depression in adduction\n'}


{'id': 'HP_0025596', 'url': 'http://purl.obolibrary.org/obo/HP_0025596', 'lbl': 'Abnormal inferior oblique muscle physiology', 'desc': 'label: Abnormal inferior oblique muscle physiology\ndefinition : A functional anomaly of the inferior oblique muscle, an extraocular muscle that has its origin on the maxillary bone just posterior to the inferior medial orbital rim and lateral to the nasolacrimal canal and that is innervated by the inferior branch of the oculomotor nerve.\nsynonyms :\n'}


{'id': 'HP_0025597', 'url': 'http://purl.obolibrary.org/obo/HP_0025597', 'lbl': 'Inferior oblique muscle restriction', 'desc': 'label: Inferior oblique muscle restriction\ndefinition : Mechanical limitation of the range of movement of the inferior oblique muscle.\nsynonyms :\n'}


{'id': 'HP_0025598', 'url': 'http://purl.obolibrary.org/obo/HP_0025598', 'lbl': 'Inferior oblique muscle weakness', 'desc': 'label: Inferior oblique muscle weakness\ndefinition : Decreased strength of the inferior oblique muscle.\nsynonyms :Inferior oblique palsy\n'}


{'id': 'HP_0025599', 'url': 'http://purl.obolibrary.org/obo/HP_0025599', 'lbl': 'Inferior oblique muscle overaction', 'desc': 'label: Inferior oblique muscle overaction\ndefinition : A common ocular motility disorder characterized by vertical incomitance of the eyes in lateral gaze. In primary inferior oblique muscle overaction, an upshoot of the adducting eye occurs when gaze is directed into the field of action of the inferior oblique muscle, producing a greater upward excursion of the adducted eye than of the abducted eye.\nsynonyms :\n'}


{'id': 'HP_0025600', 'url': 'http://purl.obolibrary.org/obo/HP_0025600', 'lbl': 'Abnormal inferior rectus muscle physiology', 'desc': 'label: Abnormal inferior rectus muscle physiology\ndefinition : A functional anomaly of the inferior rectus muscle, which is innervated by the inferior division of oculomotor nerve and functions in the depression, adduction, and lateral rotation (extortion) of the eye.\nsynonyms :\n'}


{'id': 'HP_0025601', 'url': 'http://purl.obolibrary.org/obo/HP_0025601', 'lbl': 'Inferior rectus muscle weakness', 'desc': 'label: Inferior rectus muscle weakness\ndefinition : Decreased strength of the inferior rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0025602', 'url': 'http://purl.obolibrary.org/obo/HP_0025602', 'lbl': 'Inferior rectus muscle restriction', 'desc': 'label: Inferior rectus muscle restriction\ndefinition : Mechanical limitation of the range of movement of the inferior rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0025603', 'url': 'http://purl.obolibrary.org/obo/HP_0025603', 'lbl': 'Abnormal superior rectus muscle physiology', 'desc': 'label: Abnormal superior rectus muscle physiology\ndefinition : A functional anomaly of the superior rectus muscle, an extraocular muscle that is innervated by the superior division of the oculomotor nerve, and whose primary function is the elevation of the globe.\nsynonyms :\n'}


{'id': 'HP_0025604', 'url': 'http://purl.obolibrary.org/obo/HP_0025604', 'lbl': 'Orbital schwannoma', 'desc': 'label: Orbital schwannoma\ndefinition : A schwannoma (benign, usually encapsulated slow growing tumor composed of Schwann cells) located in the orbit.\nsynonyms :\n'}


{'id': 'HP_0025605', 'url': 'http://purl.obolibrary.org/obo/HP_0025605', 'lbl': 'Lid lag on downgaze', 'desc': 'label: Lid lag on downgaze\ndefinition : Delayed descent of the upper eyelid on downgaze. Also described by some authors as von Graefe sign.\nsynonyms :Eyelid lag; Lid lag; von Graefe sign\n'}


{'id': 'HP_0025606', 'url': 'http://purl.obolibrary.org/obo/HP_0025606', 'lbl': 'Abnormal medial rectus muscle physiology', 'desc': 'label: Abnormal medial rectus muscle physiology\ndefinition : A functional anomaly of the medial rectus muscle, an extraocular muscle that is innervated by the inferior division of the oculomotor nerve and whose sole action is the adduction of the eyeball.\nsynonyms :\n'}


{'id': 'HP_0025607', 'url': 'http://purl.obolibrary.org/obo/HP_0025607', 'lbl': 'Upper eyelid entropion', 'desc': 'label: Upper eyelid entropion\ndefinition : An inward turning (inversion) of the margin of the upper eyelid.\nsynonyms :\n'}


{'id': 'HP_0025608', 'url': 'http://purl.obolibrary.org/obo/HP_0025608', 'lbl': 'Cicatricial ectropion', 'desc': 'label: Cicatricial ectropion\ndefinition : An outward turning (eversion) or rotation of the eyelid margin (i.e., ectropion) caused by shortening or contraction of the anterior or middle lamellae related to scarring.\nsynonyms :\n'}


{'id': 'HP_0025609', 'url': 'http://purl.obolibrary.org/obo/HP_0025609', 'lbl': 'Anterior blepharitis', 'desc': 'label: Anterior blepharitis\ndefinition : A type of blepharitis that affects the eyelid skin, base of the eyelashes, and the eyelash follicles.\nsynonyms :\n'}


{'id': 'HP_0025610', 'url': 'http://purl.obolibrary.org/obo/HP_0025610', 'lbl': 'Posterior blepharitis', 'desc': 'label: Posterior blepharitis\ndefinition : A type of blepharitis that affects the meibomian glands and meibomian gland orifices. This abnormality can be associated with a spectrum of appearances ranging from meibomian seborrhoea (foaming meibomian gland secretions) and meibomianitis (inflamed meibomian glands), to chalazia.\nsynonyms :Meibomian gland dysfunction; Meibomian gland disease\n'}


{'id': 'HP_0025611', 'url': 'http://purl.obolibrary.org/obo/HP_0025611', 'lbl': 'Epicanthus superciliaris', 'desc': 'label: Epicanthus superciliaris\ndefinition : A type of epicanthus in which more extensive epicanthal folds with their origins in the eyebrow cover, pass in front of and lateral to the medial canthus (middle corner of the eye).\nsynonyms :\n'}


{'id': 'HP_0025612', 'url': 'http://purl.obolibrary.org/obo/HP_0025612', 'lbl': 'Corneal astigmatism', 'desc': 'label: Corneal astigmatism\ndefinition : A type of refractive error related abnormal curvatures on the anterior or posterior surface of the cornea.\nsynonyms :\n'}


{'id': 'HP_0025613', 'url': 'http://purl.obolibrary.org/obo/HP_0025613', 'lbl': 'Focal emotional seizure', 'desc': 'label: Focal emotional seizure\ndefinition : Seizures presenting with an emotion or the appearance of having an emotion as an early prominent feature, such as fear, spontaneous joy or euphoria, laughing (gelastic), or crying, (dacrystic). These emotional seizures may occur with or without objective clinical signs of a seizure evident to the observer.\nsynonyms :Affective seizure; Emotional seizure; Focal affective seizure; Partial emotional seizure\n'}


{'id': 'HP_0025615', 'url': 'http://purl.obolibrary.org/obo/HP_0025615', 'lbl': 'Abscess', 'desc': 'label: Abscess\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025616', 'url': 'http://purl.obolibrary.org/obo/HP_0025616', 'lbl': 'Sterile abscess', 'desc': 'label: Sterile abscess\ndefinition : An abscess not caused by infection with pyogenic bacteria. Operationally, a sterile abscess is inferred if investigations of an abscess fail to reveal evidence of pathogenic organisms.\nsynonyms :\n'}


{'id': 'HP_0025617', 'url': 'http://purl.obolibrary.org/obo/HP_0025617', 'lbl': 'Abnormal plasma cell count', 'desc': 'label: Abnormal plasma cell count\ndefinition : An abnormal number of plasma cells in the blood circulation. Plasma cells are the the effector cells dedicated to the production of a high amount of antibodies.\nsynonyms :\n'}


{'id': 'HP_0025618', 'url': 'http://purl.obolibrary.org/obo/HP_0025618', 'lbl': 'Reduced plasma cell count', 'desc': 'label: Reduced plasma cell count\ndefinition : An abnormally low number of plasma cells in the blood circulation. Plasma cells are the the effector cells dedicated to the production of a high amount of antibodies.\nsynonyms :\n'}


{'id': 'HP_0025619', 'url': 'http://purl.obolibrary.org/obo/HP_0025619', 'lbl': 'Elevated plasma cell count', 'desc': 'label: Elevated plasma cell count\ndefinition : An abnormally high number of plasma cells in the blood circulation. Plasma cells are the the effector cells dedicated to the production of a high amount of antibodies.\nsynonyms :\n'}


{'id': 'HP_0025620', 'url': 'http://purl.obolibrary.org/obo/HP_0025620', 'lbl': 'Abnormal proportion of CD4+ central memory cells', 'desc': 'label: Abnormal proportion of CD4+ central memory cells\ndefinition : An abnormal proportion of central memory CD4+ T cells. These are memory cells that are located in the secondary lymphoid organs. These cells may have a CD3/CD4/CD62L+/CD45RA- phenotype.\nsynonyms :Abnormal proportion of central memory CD4+, alpha-beta T cells\n'}


{'id': 'HP_0025621', 'url': 'http://purl.obolibrary.org/obo/HP_0025621', 'lbl': 'obsolete Increased proportion of CD4+ central memory cells', 'desc': 'label: obsolete Increased proportion of CD4+ central memory cells\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025622', 'url': 'http://purl.obolibrary.org/obo/HP_0025622', 'lbl': 'obsolete Decreased proportion of CD4+ central memory cells', 'desc': 'label: obsolete Decreased proportion of CD4+ central memory cells\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025623', 'url': 'http://purl.obolibrary.org/obo/HP_0025623', 'lbl': 'Abnormal proportion of CD4+ effector memory cells', 'desc': 'label: Abnormal proportion of CD4+ effector memory cells\ndefinition : An abnormal proportion of effector memory CD4+ T cells compared to the total number of T cells in the blood. These are memory cells that are short-lived cells that migrate to the site of an infection and attempt to eliminate the pathogen. These cells have the phenotype CD3-positive, CD4-positive, CD62L-negative, CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.\nsynonyms :Abnormal proportion of CD4-positive effector memory cells; Abnormal proportion of effector memory CD4-positive, alpha-beta T cells\n'}


{'id': 'HP_0025624', 'url': 'http://purl.obolibrary.org/obo/HP_0025624', 'lbl': 'Reduced proportion of CD4+ effector memory T cells', 'desc': 'label: Reduced proportion of CD4+ effector memory T cells\ndefinition : An abnormally decreased proportion of effector memory CD4+ T cells compared to the total number of T cells in the blood. These are memory cells that are short-lived cells that migrate to the site of an infection and attempt to eliminate the pathogen. These cells have the phenotype CD3-positive, CD4-positive, CD62L-negative, CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative.\nsynonyms :Decreased proportion of CD4+ effector memory T cells; Decreased proportion of CD4-positive effector memory T cells; Decreased proportion of effector memory CD4-positive, alpha-beta T cells\n'}


{'id': 'HP_0025625', 'url': 'http://purl.obolibrary.org/obo/HP_0025625', 'lbl': 'Elevated proportion of CD4+ effector memory T cells', 'desc': 'label: Elevated proportion of CD4+ effector memory T cells\ndefinition : An abnormally increased proportion of effector memory CD4+ T cells. These are memory cells that are short-lived cells that migrate to the site of an infection and attempt to eliminate the pathogen. These cells may have a CD3/CD4/CD62L-/CD45RA phenotype.\nsynonyms :Increased proportion of CD4+ effector memory T cells; Increased proportion of CD4-positive effector memory T cells; Increased proportion of effector CD4-positive, alpha-beta T cells\n'}


{'id': 'HP_0025626', 'url': 'http://purl.obolibrary.org/obo/HP_0025626', 'lbl': 'Increased circulating oleate level', 'desc': 'label: Increased circulating oleate level\ndefinition : An abnormally high concentration of oleic acid (oleate) in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0025627', 'url': 'http://purl.obolibrary.org/obo/HP_0025627', 'lbl': 'Increased circulating octadecanoate level', 'desc': 'label: Increased circulating octadecanoate level\ndefinition : An abnormally high concentration of octadecanoate in the blood circulation. Octadecanoate is a fatty acid anion 18:0 that is the conjugate base of octadecanoic acid (stearic acid).\nsynonyms :\n'}


{'id': 'HP_0025628', 'url': 'http://purl.obolibrary.org/obo/HP_0025628', 'lbl': 'Increased circulating myristoleate level', 'desc': 'label: Increased circulating myristoleate level\ndefinition : An abnormally high concentration of myristoleate in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0025629', 'url': 'http://purl.obolibrary.org/obo/HP_0025629', 'lbl': 'Anti-myelin-associated glycoprotein antibody positivity', 'desc': 'label: Anti-myelin-associated glycoprotein antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against myelin-associated glycoprotein (MAG).\nsynonyms :\n'}


{'id': 'HP_0025630', 'url': 'http://purl.obolibrary.org/obo/HP_0025630', 'lbl': 'Argininosuccinic aciduria', 'desc': 'label: Argininosuccinic aciduria\ndefinition : Increased amount of argininosuccinate in the urine.\nsynonyms :\n'}


{'id': 'HP_0025631', 'url': 'http://purl.obolibrary.org/obo/HP_0025631', 'lbl': 'Alpha-aminobutyric aciduria', 'desc': 'label: Alpha-aminobutyric aciduria\ndefinition : Increased amount of alpha-aminobutyric acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0025632', 'url': 'http://purl.obolibrary.org/obo/HP_0025632', 'lbl': 'Reduced reactive oxygen species production in neutrophils', 'desc': 'label: Reduced reactive oxygen species production in neutrophils\ndefinition : An abnormal reduction in the amount of reactive oxygen produced by neutrophils in the respiratory burst.\nsynonyms :\n'}


{'id': 'HP_0025633', 'url': 'http://purl.obolibrary.org/obo/HP_0025633', 'lbl': 'Abnormal ureter morphology', 'desc': 'label: Abnormal ureter morphology\ndefinition : A structural abnormality of the ureter. The ureter is the duct by which urine passes from the kidney to the bladder.\nsynonyms :\n'}


{'id': 'HP_0025634', 'url': 'http://purl.obolibrary.org/obo/HP_0025634', 'lbl': 'Abnormal ureter physiology', 'desc': 'label: Abnormal ureter physiology\ndefinition : A functional abnormality of the ureter. The ureter is the duct by which urine passes from the kidney to the bladder.\nsynonyms :\n'}


{'id': 'HP_0025635', 'url': 'http://purl.obolibrary.org/obo/HP_0025635', 'lbl': 'Ureteral polyp', 'desc': 'label: Ureteral polyp\ndefinition : A growth protruding from the mucous membrane of the ureter. Ureteral polyps can be attached to the ureter by a broad base or a thin stalk.\nsynonyms :Polyp of the ureter; Ureter polyp\n'}


{'id': 'HP_0025636', 'url': 'http://purl.obolibrary.org/obo/HP_0025636', 'lbl': 'Endometritis', 'desc': 'label: Endometritis\ndefinition : Inflammation of the inner lining of the uterus (endometrium).\nsynonyms :Endometrial inflammation; Inflammation of the inner lining of the uterus\n'}


{'id': 'HP_0025637', 'url': 'http://purl.obolibrary.org/obo/HP_0025637', 'lbl': 'Vasospasm', 'desc': 'label: Vasospasm\ndefinition : Narrowing of an artery due to constriction of the blood vessels.\nsynonyms :Angiospasm; Blood vessel spasm; Vascular spasm\n'}


{'id': 'HP_0025638', 'url': 'http://purl.obolibrary.org/obo/HP_0025638', 'lbl': 'Elevated urinary N-butyrylglycine', 'desc': 'label: Elevated urinary N-butyrylglycine\ndefinition : An increased level of N-butyrylglycine in the urine.\nsynonyms :\n'}


{'id': 'HP_0025639', 'url': 'http://purl.obolibrary.org/obo/HP_0025639', 'lbl': 'Increased urinary zinc level', 'desc': 'label: Increased urinary zinc level\ndefinition : An abnormally elevated amount of zinc in the urine, typically as assessed by a 24 hour urine collection.\nsynonyms :\n'}


{'id': 'HP_0025640', 'url': 'http://purl.obolibrary.org/obo/HP_0025640', 'lbl': 'Abnormal urinary mineral level', 'desc': 'label: Abnormal urinary mineral level\ndefinition : An abnormal concentration or amount of a mineral in the urine. Medically relevant minerals include calcium, phosphorus, potassium, sodium, chloride, magnesium, iron, zinc, iodine, chromium, copper, fluoride, molybdenum, manganese, and selenium.\nsynonyms :\n'}


{'id': 'HP_0025641', 'url': 'http://purl.obolibrary.org/obo/HP_0025641', 'lbl': 'Elevated circulating glycolate concentration', 'desc': 'label: Elevated circulating glycolate concentration\ndefinition : An abnormally increased concentration of glycolate in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0025643', 'url': 'http://purl.obolibrary.org/obo/HP_0025643', 'lbl': 'Tarlov cyst', 'desc': 'label: Tarlov cyst\ndefinition : A cerebrospinal fluid-filled nerve root cyst most often localized in the sacral spine.\nsynonyms :Perineural cyst\n'}


{'id': 'HP_0025644', 'url': 'http://purl.obolibrary.org/obo/HP_0025644', 'lbl': 'Fixation-off epileptiform discharges', 'desc': 'label: Fixation-off epileptiform discharges\ndefinition : Fixation off sensitivity (FOS) is characterized by posterior or generalized epileptiform discharges that consistently occur with conditions that eliminate central vision, such as closed eyes, complete darkness, modified Ganzfeld stimulation (using a large white surface without visual cues), and Frenzel lenses. The FOS electroencephalogram (EEG) pattern usually consists of spikes/polyspikes and waves localized in occipital regions (bilateral or unilateral) or generalized discharges. It is usually inhibited by fixation of gaze, observing patterns, or intermittent photic stimulation (e.g., flashing light or patterns used as stimuli during the recording of the EEG).\nsynonyms :Fixation-off sensitivity\n'}


{'id': 'HP_0025646', 'url': 'http://purl.obolibrary.org/obo/HP_0025646', 'lbl': 'Bilateral polymicrogyria', 'desc': 'label: Bilateral polymicrogyria\ndefinition : Polymicrogyria that affects all or some of both cerebral hemispheres.\nsynonyms :\n'}


{'id': 'HP_0025647', 'url': 'http://purl.obolibrary.org/obo/HP_0025647', 'lbl': 'Steroid-sensitive nephrotic syndrome', 'desc': 'label: Steroid-sensitive nephrotic syndrome\ndefinition : A type of nephrotic syndrome in which complete remission (albumin urine dipstick negative/trace or proteinuria <4mg/m2/d or urinary protein to creatinine ratio <200mg/g (<20 mg/mmol) for 3 consecutive days) is achieved within initial 4 weeks of corticosteroid therapy.\nsynonyms :SSNS\n'}


{'id': 'HP_0025648', 'url': 'http://purl.obolibrary.org/obo/HP_0025648', 'lbl': 'Steroid-sensitive nephrotic syndrome with infrequent relapses', 'desc': 'label: Steroid-sensitive nephrotic syndrome with infrequent relapses\ndefinition : A type of steroid-sensitive nephrotic syndrome in which relapses occur at a frequency of one relapse (albumin urine dipstick at least 3+ or proteinuria over 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) within 6 months of initial response, or one to three relapses in any 12-month period.\nsynonyms :\n'}


{'id': 'HP_0025649', 'url': 'http://purl.obolibrary.org/obo/HP_0025649', 'lbl': 'Steroid-sensitive nephrotic syndrome with frequent relapses', 'desc': 'label: Steroid-sensitive nephrotic syndrome with frequent relapses\ndefinition : A type of steroid-sensitive nephrotic syndrome in which relapses occur at a frequency of two or more relapses (albumin urine dipstick at least 3+ or proteinuria over 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) within 6 months of initial response or four or more relapses in any 12-month period.\nsynonyms :\n'}


{'id': 'HP_0025650', 'url': 'http://purl.obolibrary.org/obo/HP_0025650', 'lbl': 'Steroid-dependent nephrotic syndrome', 'desc': 'label: Steroid-dependent nephrotic syndrome\ndefinition : A type of nephrotic syndrome in which two consecutive relapses (albumin urine dipstick at least 3+ or proteinuria greater than 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) occur during corticosteroid therapy, or within 14 days of ceasing therapy.\nsynonyms :SDNS\n'}


{'id': 'HP_0025652', 'url': 'http://purl.obolibrary.org/obo/HP_0025652', 'lbl': 'Abnormal placental adhesion into the uterine wall', 'desc': 'label: Abnormal placental adhesion into the uterine wall\ndefinition : Abnormal placental adhesion is characterized by an anomalous adherence of the placenta to the uterine wall. Based on the degree of adhesion, placental invasion can be classified into accreta, increta, or percreta.\nsynonyms :\n'}


{'id': 'HP_0025653', 'url': 'http://purl.obolibrary.org/obo/HP_0025653', 'lbl': 'Placenta percreta', 'desc': 'label: Placenta percreta\ndefinition : Placenta percreta is a rare form of morbidly adherent placenta with penetration through the myometrium reaching serosa and even adjacent pelvic organs.\nsynonyms :Abnormal placental pentration beyond the uterine wall\n'}


{'id': 'HP_0025654', 'url': 'http://purl.obolibrary.org/obo/HP_0025654', 'lbl': 'Placenta acreta', 'desc': 'label: Placenta acreta\ndefinition : Abnormally firm adherence of the placenta to the uterine wall.\nsynonyms :\n'}


{'id': 'HP_0025655', 'url': 'http://purl.obolibrary.org/obo/HP_0025655', 'lbl': 'Placenta increta', 'desc': 'label: Placenta increta\ndefinition : Abnormal placental pentration into but not beyond the uterine wall.\nsynonyms :\n'}


{'id': 'HP_0025656', 'url': 'http://purl.obolibrary.org/obo/HP_0025656', 'lbl': 'Prenatal double bubble sign', 'desc': 'label: Prenatal double bubble sign\ndefinition : Sonographic detection of a double bubble sign in the upper abdomen is strongly indicative of duodenal obstruction. One bubble represents fetal stomach, and the other is attributed to a dilated proximal part of the duodenum; continuity between both bubbles is required for the sign.\nsynonyms :\n'}


{'id': 'HP_0025657', 'url': 'http://purl.obolibrary.org/obo/HP_0025657', 'lbl': 'Abnormal umbilical blood flow measurement', 'desc': 'label: Abnormal umbilical blood flow measurement\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025658', 'url': 'http://purl.obolibrary.org/obo/HP_0025658', 'lbl': 'obsolete Abnormal umbilical artery Doppler pattern in pregnancy', 'desc': 'label: obsolete Abnormal umbilical artery Doppler pattern in pregnancy\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025659', 'url': 'http://purl.obolibrary.org/obo/HP_0025659', 'lbl': 'Decreased circulating creatine kinase concentration', 'desc': 'label: Decreased circulating creatine kinase concentration\ndefinition : A reduction in the level of the enzyme creatine kinase (also known as creatine phosphokinase (CK; EC 2.7.3.2) in the blood.\nsynonyms :\n'}


{'id': 'HP_0025660', 'url': 'http://purl.obolibrary.org/obo/HP_0025660', 'lbl': 'Chiari type II malformation', 'desc': 'label: Chiari type II malformation\ndefinition : A type of Chiari malformation that consists of brainstem herniation and a towering cerebellum in addition to the herniated cerebellar tonsils and vermis due to an open distal spinal dysraphism/myelomeningocele.\nsynonyms :Arnold-Chiari type II malformation\n'}


{'id': 'HP_0025661', 'url': 'http://purl.obolibrary.org/obo/HP_0025661', 'lbl': 'Chiari type III malformation', 'desc': 'label: Chiari type III malformation\ndefinition : A type of Chiari malformation that involves herniation of the hindbrain (cerebellum with or without the brainstem) into a low occipital or high cervical meningoencephalocele.\nsynonyms :Arnold-Chiari type III malformation\n'}


{'id': 'HP_0025662', 'url': 'http://purl.obolibrary.org/obo/HP_0025662', 'lbl': 'Abnormal fetal skeletal morphology', 'desc': 'label: Abnormal fetal skeletal morphology\ndefinition : An anomalous structural finding of the fetal skeleton. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other terms from the skeletal hierarchy can also be used to describe fetal phenotypes.\nsynonyms :\n'}


{'id': 'HP_0025663', 'url': 'http://purl.obolibrary.org/obo/HP_0025663', 'lbl': 'Reduced fetal femur/foot length ratio', 'desc': 'label: Reduced fetal femur/foot length ratio\ndefinition : This ratio relates the length of the fetal femur to that of the fetal foot. The ratio is approximately 1 throughout the age range of 14 to 40 weeks of gestation. A substantial reduction in the raio can help differentiate fetuses that have dysplastic limb reduction from those whose limbs are short because of constitutional factors or IUGR. It can reduce the problem of an unknown gestational age and help to distinguish between fetal skeletal dysplasia and intrauterine growth retardation caused by other factors.\nsynonyms :\n'}


{'id': 'HP_0025664', 'url': 'http://purl.obolibrary.org/obo/HP_0025664', 'lbl': 'Moderate to late preterm birth', 'desc': 'label: Moderate to late preterm birth\ndefinition : Birth at 32 to 36 completed weeks of gestation.\nsynonyms :\n'}


{'id': 'HP_0025665', 'url': 'http://purl.obolibrary.org/obo/HP_0025665', 'lbl': 'Extremely preterm birth', 'desc': 'label: Extremely preterm birth\ndefinition : Birth before 28 completed weeks of gestation (up to and including 27 weeks and 6 days of gestation).\nsynonyms :\n'}


{'id': 'HP_0025666', 'url': 'http://purl.obolibrary.org/obo/HP_0025666', 'lbl': 'Very preterm birth', 'desc': 'label: Very preterm birth\ndefinition : Birth before 32 completed weeks of gestation (28 up to but not including 32 weeks).\nsynonyms :\n'}


{'id': 'HP_0025667', 'url': 'http://purl.obolibrary.org/obo/HP_0025667', 'lbl': 'Fetal neck anomaly', 'desc': 'label: Fetal neck anomaly\ndefinition : A structural anomaly in the fetal neck region. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes.\nsynonyms :\n'}


{'id': 'HP_0025668', 'url': 'http://purl.obolibrary.org/obo/HP_0025668', 'lbl': 'Abnormal neck morphology', 'desc': 'label: Abnormal neck morphology\ndefinition : Any structural anomaly of the neck region.\nsynonyms :\n'}


{'id': 'HP_0025669', 'url': 'http://purl.obolibrary.org/obo/HP_0025669', 'lbl': 'Abnormal neck physiology', 'desc': 'label: Abnormal neck physiology\ndefinition : Any functional anomaly of the neck region.\nsynonyms :\n'}


{'id': 'HP_0025670', 'url': 'http://purl.obolibrary.org/obo/HP_0025670', 'lbl': 'Syntelencephaly', 'desc': 'label: Syntelencephaly\ndefinition : Syntelencephaly is a rare malformation that consists of an abnormal midline connection of the cerebral hemispheres in the posterior frontal and parietal regions, with interhemispheric separation of the basal forebrain, anterior frontal lobes, and occipital regions.\nsynonyms :\n'}


{'id': 'HP_0025671', 'url': 'http://purl.obolibrary.org/obo/HP_0025671', 'lbl': 'Fetal pericardial effusion', 'desc': 'label: Fetal pericardial effusion\ndefinition : An abnormal accumulation of fluid in which the heart is partially or completely surrounded by fluid that is seen in all views and the thickness of the fluid as observed by prenatal ultrasound is above age-dependent norms.\nsynonyms :\n'}


{'id': 'HP_0025672', 'url': 'http://purl.obolibrary.org/obo/HP_0025672', 'lbl': 'Fetal skin edema', 'desc': 'label: Fetal skin edema\ndefinition : A separation of skin in one or more regions of the body or even along the entire length of body wall (to a degree greater than gestational-age related norms) related to pathologically increased fluid accumulation in the subcutaneous tissue.\nsynonyms :\n'}


{'id': 'HP_0025673', 'url': 'http://purl.obolibrary.org/obo/HP_0025673', 'lbl': 'Loculated ascites', 'desc': 'label: Loculated ascites\ndefinition : A type of ascites (peritoneal fluid collection) that is divided into loculi (compartments) by septa (fibrous walls). Ascites fluid can become loculated when confined by adhesions, malignancy or infection.\nsynonyms :Septated ascites\n'}


{'id': 'HP_0025674', 'url': 'http://purl.obolibrary.org/obo/HP_0025674', 'lbl': 'Meconium pseudocyst', 'desc': 'label: Meconium pseudocyst\ndefinition : A meconium-containing cyst in the peritoneal space . Meconium pseudocysts form in the presence of meconium peritonitis, which is defined as a sterile peritonitis caused by escape of meconium from the intestinal tract into the general peritoneal cavity during the fetal or perinatal period. When the extruded meconium becomes walled off, it can form a rim-calcified mass representing the meconium pseudocyst.\nsynonyms :\n'}


{'id': 'HP_0025675', 'url': 'http://purl.obolibrary.org/obo/HP_0025675', 'lbl': 'Premature closure of the ductus arteriosus', 'desc': 'label: Premature closure of the ductus arteriosus\ndefinition : A prenatal partial or complete closure of the ductus arteriosus (i.e., prior to delivery).\nsynonyms :Fetal PAD narrowing-closure; Fetal PDA narrowing-closure; Fetal arterial duct narrowing-closure; Fetal ductus arteriosus narrowing-closure; Idiopathic constriction of the fetal ductus arteriosus; PCDA\n'}


{'id': 'HP_0025676', 'url': 'http://purl.obolibrary.org/obo/HP_0025676', 'lbl': 'Fetal pleural effusion', 'desc': 'label: Fetal pleural effusion\ndefinition : Fetal pleural effusion is the accumulation of excess fluid in the layers of tissue (pleura) lining the lungs and wall of the chest. It may be primary, also termed hydrothorax, occurring as an isolated finding or it may be secondary, most commonly resulting from non-immune hydrops.\nsynonyms :\n'}


{'id': 'HP_0025677', 'url': 'http://purl.obolibrary.org/obo/HP_0025677', 'lbl': 'Fetal chylothorax', 'desc': 'label: Fetal chylothorax\ndefinition : The presence of chyle (a type of lipid-rich lymph) in the pleural space (the space surrounding the lung) as observed in a fetus.\nsynonyms :\n'}


{'id': 'HP_0025678', 'url': 'http://purl.obolibrary.org/obo/HP_0025678', 'lbl': 'Fetal hydrothorax', 'desc': 'label: Fetal hydrothorax\ndefinition : Accumulation of lymphatic fluid in the pleural space. This finding is usually observed by prenatal sonography. Once neonatal feeding is established and the lymphatic fluid contains chyle, transformation to chylothorax may be observed.\nsynonyms :\n'}


{'id': 'HP_0025679', 'url': 'http://purl.obolibrary.org/obo/HP_0025679', 'lbl': 'Diskitis', 'desc': 'label: Diskitis\ndefinition : Inflammation of an intervertebral disc or disk space.\nsynonyms :Discitis\n'}


{'id': 'HP_0025680', 'url': 'http://purl.obolibrary.org/obo/HP_0025680', 'lbl': 'Compound muscle action potential amplitude facilitation', 'desc': 'label: Compound muscle action potential amplitude facilitation\ndefinition : Compound muscle action potential amplitude (CMAP) facilitation denotes an increase in tendon reflexes, strength, or CMAP amplitude after 10 seconds of maximal voluntary contraction.\nsynonyms :CMAP facilitation\n'}


{'id': 'HP_0025681', 'url': 'http://purl.obolibrary.org/obo/HP_0025681', 'lbl': 'Distal clavicular thinning', 'desc': 'label: Distal clavicular thinning\ndefinition : Abnormally reduced diameter (cross section) of the clavicles that is limited to the distal region.\nsynonyms :\n'}


{'id': 'HP_0025682', 'url': 'http://purl.obolibrary.org/obo/HP_0025682', 'lbl': 'Crouch gait', 'desc': 'label: Crouch gait\ndefinition : A gait disturbance that is characterized by excessive ankle dorsiflexion, knee and hip flexion during the stance phase.\nsynonyms :\n'}


{'id': 'HP_0025683', 'url': 'http://purl.obolibrary.org/obo/HP_0025683', 'lbl': 'Abnormal amyloid beta 42 peptide CSF concentration', 'desc': 'label: Abnormal amyloid beta 42 peptide CSF concentration\ndefinition : Any deviation from the normal concentration of amyloid beta 42 peptide in the cerebrospinal fluid (CSF). Amyloid beta is a peptide of 36-43 amino acids that is processed from the Amyloid precursor protein. ABeta42, which is 42 amino acids in length, is the longer form.\nsynonyms :\n'}


{'id': 'HP_0025684', 'url': 'http://purl.obolibrary.org/obo/HP_0025684', 'lbl': 'Decreased amyloid beta 42 peptide CSF concentration', 'desc': 'label: Decreased amyloid beta 42 peptide CSF concentration\ndefinition : A reduction from the normal concentration of amyloid beta 42 peptide in the cerebrospinal fluid (CSF).\nsynonyms :\n'}


{'id': 'HP_0025685', 'url': 'http://purl.obolibrary.org/obo/HP_0025685', 'lbl': 'Increased amyloid beta 42 peptide CSF concentration', 'desc': 'label: Increased amyloid beta 42 peptide CSF concentration\ndefinition : An elevation above the normal concentration of amyloid beta 42 peptide in the cerebrospinal fluid (CSF).\nsynonyms :\n'}


{'id': 'HP_0025686', 'url': 'http://purl.obolibrary.org/obo/HP_0025686', 'lbl': 'Abnormal amyloid beta 40 peptide CSF concentration', 'desc': 'label: Abnormal amyloid beta 40 peptide CSF concentration\ndefinition : Any deviation from the normal concentration of amyloid beta 42 peptide in the cerebrospinal fluid (CSF). Amyloid beta is a peptide of 36-43 amino acids that is processed from the Amyloid precursor protein. ABeta40, which is 40 amino acids in length, is the shorter form.\nsynonyms :Abnormal Abeta 40 level; Abnormal beta amyloid 40 level\n'}


{'id': 'HP_0025687', 'url': 'http://purl.obolibrary.org/obo/HP_0025687', 'lbl': 'Increased amyloid beta 40 peptide CSF concentration', 'desc': 'label: Increased amyloid beta 40 peptide CSF concentration\ndefinition : An elevation above the normal concentration of amyloid beta 40 peptide in the cerebrospinal fluid (CSF).\nsynonyms :\n'}


{'id': 'HP_0025688', 'url': 'http://purl.obolibrary.org/obo/HP_0025688', 'lbl': 'Abnormal amyloid beta peptide CSF concentration', 'desc': 'label: Abnormal amyloid beta peptide CSF concentration\ndefinition : Any anomaly in the concentration of a cleaved APP amyloid beta protein fragment in the cerebrospinal fluid.\nsynonyms :\n'}


{'id': 'HP_0025689', 'url': 'http://purl.obolibrary.org/obo/HP_0025689', 'lbl': 'Extra-abdominal umbilical vein varix', 'desc': 'label: Extra-abdominal umbilical vein varix\ndefinition : Focal dilatation of the extra-abdominal portion of the umbilical vein. An extra-abdominal umbilical varix is difficult to diagnose prenatally as it can appear like a cyst on ultrasound prior to birth.\nsynonyms :\n'}


{'id': 'HP_0025690', 'url': 'http://purl.obolibrary.org/obo/HP_0025690', 'lbl': 'Fetal intra-abdominal umbilical vein varix', 'desc': 'label: Fetal intra-abdominal umbilical vein varix\ndefinition : Fetal intra-abdominal umbilical vein varix (FIUVV) is defined by the focal dilatation of the fetal umbilical vein between its entry in the abdomen and its ending in the portal system. The dilatation can be defined using one of the following criteria: a portion of intra-abdominal umbilical vein that is at least 50% wider than the non-dilated portion; a dilatation of 9 mm or more, or a dilatation greater than 2 SD above the mean value for gestational age.\nsynonyms :FIUVV; Fetal umbilical vein dilatation\n'}


{'id': 'HP_0025691', 'url': 'http://purl.obolibrary.org/obo/HP_0025691', 'lbl': 'Impaired fasting glucose', 'desc': 'label: Impaired fasting glucose\ndefinition : Impaired fasting glucose (IFG) is indicated by a fasting plasma glucose above normal but below the diabetic range. Levels between 110 mg/dl (6.1 mmol/l) to 125 mg/dl (6.9 mmol/l) are diagnostic of IFG.\nsynonyms :\n'}


{'id': 'HP_0025692', 'url': 'http://purl.obolibrary.org/obo/HP_0025692', 'lbl': 'Atelencephaly', 'desc': 'label: Atelencephaly\ndefinition : A defect of development of the brain characterized by absence of the telencephalon (embryonic structure from which the mature cerebrum develops).\nsynonyms :\n'}


{'id': 'HP_0025693', 'url': 'http://purl.obolibrary.org/obo/HP_0025693', 'lbl': 'Pituitary macroadenoma', 'desc': 'label: Pituitary macroadenoma\ndefinition : A pituitary gland adenoma that is larger than 10mm.\nsynonyms :Pituitary gland macroadenoma\n'}


{'id': 'HP_0025694', 'url': 'http://purl.obolibrary.org/obo/HP_0025694', 'lbl': 'Pituitary microadenoma', 'desc': 'label: Pituitary microadenoma\ndefinition : A pituitary adenoma that is less than 10 mm in diameter.\nsynonyms :\n'}


{'id': 'HP_0025695', 'url': 'http://purl.obolibrary.org/obo/HP_0025695', 'lbl': 'Mucus plug', 'desc': 'label: Mucus plug\ndefinition : Mucus that is abnormally thick in consistency (ie, inspissated) and plugs the airway is known as a mucus plug. Mucus plugs consist of mucins and cells and can partially or completely obstruct one or more airways and cause serious consequences, including atelectasis and recurrent infection.\nsynonyms :\n'}


{'id': 'HP_0025696', 'url': 'http://purl.obolibrary.org/obo/HP_0025696', 'lbl': 'Airway casts', 'desc': 'label: Airway casts\ndefinition : A replicate of airways from accumulated and condensed mucous and cellular material. These semisolid occlusions take the shape of the airway within they are formed, leading to obstruction of the tracheobronchial tree with consecutive respiratory insufficiency. Based on their principal composition, one can differentiate fibrin casts and mucin casts. Plastic bronchitis is the name of the condition characterized by the formation of airway casts.\nsynonyms :\n'}


{'id': 'HP_0025697', 'url': 'http://purl.obolibrary.org/obo/HP_0025697', 'lbl': 'Fibrin casts', 'desc': 'label: Fibrin casts\ndefinition : A type of airway casts that consist of plasma components and inflammatory cells.\nsynonyms :Cellular airway casts; Diphtheroid membranes; Pseudomembranes; Type I airway casts\n'}


{'id': 'HP_0025698', 'url': 'http://purl.obolibrary.org/obo/HP_0025698', 'lbl': 'Mucin casts', 'desc': 'label: Mucin casts\ndefinition : A type of airway casts that consist of impacted mucus.\nsynonyms :Acellular airway casts; Type II airway casts\n'}


{'id': 'HP_0025699', 'url': 'http://purl.obolibrary.org/obo/HP_0025699', 'lbl': 'Perisylvian FDG hypermetabolism', 'desc': 'label: Perisylvian FDG hypermetabolism\ndefinition : 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (FDG-PET/CT) evaluates the glucose metabolism of the brain. FDG uptake is interpreted to represent glycolysis. This term therefore represents an abnormally increased FDG uptake (increased glucose metabolism) in the region of the brain that surrounds the Sylvian fissure.\nsynonyms :Perisylvian hypermetabolism in FDG PET\n'}


{'id': 'HP_0025700', 'url': 'http://purl.obolibrary.org/obo/HP_0025700', 'lbl': 'Anhydramnios', 'desc': 'label: Anhydramnios\ndefinition : A complete or near-complete lack of amniotic fluid surrounding a fetus. This finding can be observed sonographically in the third trimesters if the deepest pocket of amniotic fluid is less than or equal to 2 cm.\nsynonyms :\n'}


{'id': 'HP_0025701', 'url': 'http://purl.obolibrary.org/obo/HP_0025701', 'lbl': 'Distended jugular lymphatic sacs', 'desc': 'label: Distended jugular lymphatic sacs\ndefinition : The jugular lymphatic sacs (JLS) are a physiological and temporary part of fetal lymphatic development. They are formed from small buds of lymphatic endothelial cells arising from the internal jugular veins. By 14 weeks gestation they have developed into lymphatic nodes which drain into the systemic circulation. Visibility of JLS on ultrasound past 14 weeks of gestation implies distension and this may be associated with raised nuchal translucency.\nsynonyms :\n'}


{'id': 'HP_0025702', 'url': 'http://purl.obolibrary.org/obo/HP_0025702', 'lbl': 'Type 1 schizencephaly', 'desc': 'label: Type 1 schizencephaly\ndefinition : A type of Schizencephaly in which there is a trans-mantle column of abnormal grey matter but no evidence of a CSF-containing cleft on MR imaging.\nsynonyms :Trans-mantle schizencephaly\n'}


{'id': 'HP_0025703', 'url': 'http://purl.obolibrary.org/obo/HP_0025703', 'lbl': 'Type 2 schizencephaly', 'desc': 'label: Type 2 schizencephaly\ndefinition : A type of Schizencephaly in which CSF-containing cleft is present with abutting lining lips of abnormal grey matter that are opposed to each other.\nsynonyms :\n'}


{'id': 'HP_0025704', 'url': 'http://purl.obolibrary.org/obo/HP_0025704', 'lbl': 'Type 3 schizencephaly', 'desc': 'label: Type 3 schizencephaly\ndefinition : A type of Schizencephaly in which CSF-containing cleft present with non-abutting lining lips of abnormal grey matter.\nsynonyms :\n'}


{'id': 'HP_0025705', 'url': 'http://purl.obolibrary.org/obo/HP_0025705', 'lbl': 'Abnormal fetal nasal bone visualization', 'desc': 'label: Abnormal fetal nasal bone visualization\ndefinition : Abnormal appearance or non-visualization (apparent absence) of the nasal bone of a fetus in first trimester sonographic screening. Assessment of the fetal nasal bone is generally performed at 11-14 weeks gestational age.\nsynonyms :\n'}


{'id': 'HP_0025706', 'url': 'http://purl.obolibrary.org/obo/HP_0025706', 'lbl': 'Absent fetal nasal bone', 'desc': 'label: Absent fetal nasal bone\ndefinition : The nasal bone is considered absent when it is not visualized on a midsagittal view of the profile. In the second trimester, a true midsagittal view of the fetal profile is obtained and magnified to fill the majority of the image space. The nasal bone appears as an echogenic linear structure below the skin edge. The optimal angle of insonation is 45 degrees to the longitudinal axis of the fetal nasal bone. If the angle of insonation is 0 or 180 degrees, the nasal bone may appear artificially absent. The presence or absence of the nasal bone may be determined at the time of the 11- to 14-week ultrasound examination and used as part of the risk assessment for aneuploidy.\nsynonyms :Absence of fetal nasal bone; Unossified nasal bone\n'}


{'id': 'HP_0025707', 'url': 'http://purl.obolibrary.org/obo/HP_0025707', 'lbl': 'Hypoplastic nasal bone', 'desc': 'label: Hypoplastic nasal bone\ndefinition : Length of the nasal bone below a predetermined cut-off as seen on antenatal ultrasound using standard imaging techniques.\nsynonyms :\n'}


{'id': 'HP_0025708', 'url': 'http://purl.obolibrary.org/obo/HP_0025708', 'lbl': 'Early young adult onset', 'desc': 'label: Early young adult onset\ndefinition : Onset of disease at an age of greater than or equal to 16 to under 19 years.\nsynonyms :\n'}


{'id': 'HP_0025709', 'url': 'http://purl.obolibrary.org/obo/HP_0025709', 'lbl': 'Intermediate young adult onset', 'desc': 'label: Intermediate young adult onset\ndefinition : Onset of disease at an age of greater than or equal to 19 to under 25 years.\nsynonyms :\n'}


{'id': 'HP_0025710', 'url': 'http://purl.obolibrary.org/obo/HP_0025710', 'lbl': 'Late young adult onset', 'desc': 'label: Late young adult onset\ndefinition : Onset of disease at an age of greater than or equal to 25 to under 40 years.\nsynonyms :\n'}


{'id': 'HP_0025711', 'url': 'http://purl.obolibrary.org/obo/HP_0025711', 'lbl': 'Convergence-retraction nystagmus', 'desc': 'label: Convergence-retraction nystagmus\ndefinition : Convergence-retraction nystagmus is an irregular, jerky nystagmus in which both eyeballs rhythmically converge and retract into the orbit, particularly on attempting an upward gaze.\nsynonyms :Convergence retraction nystagmus\n'}


{'id': 'HP_0025712', 'url': 'http://purl.obolibrary.org/obo/HP_0025712', 'lbl': 'Spontaneous chorioamniotic separation', 'desc': 'label: Spontaneous chorioamniotic separation\ndefinition : Persistence separation of the chorionic and amnionic membranes after the 16th week of gestation (not as a result of a procedure such as amniocentesis).\nsynonyms :Amnion-chorion separation\n'}


{'id': 'HP_0025713', 'url': 'http://purl.obolibrary.org/obo/HP_0025713', 'lbl': 'Neurite dystrophy', 'desc': 'label: Neurite dystrophy\ndefinition : Dystrophic neurites are abnormal neuronal processes characterized microscopically by aberrant sprouting, dystrophic expansion, and accumulation of various cellular organelles and cytoskeletal/signaling proteins.\nsynonyms :Dystrophic neurite\n'}


{'id': 'HP_0025714', 'url': 'http://purl.obolibrary.org/obo/HP_0025714', 'lbl': 'Cerebral cortical microinfarct', 'desc': 'label: Cerebral cortical microinfarct\ndefinition : An infarct located on the outer layer of the cerebrum that can only be observed microscopically. Cerebral microinfarcts are typically defined as sharply delimited microscopic regions of cellular death or tissue necrosis, sometimes with cavitation (that is, a central fluid-filled cavity). The term microscopic denotes that these lesions are not visible by gross inspection of the brain but seen by light microscopy. The term infarct is most commonly used for ischemia-related tissue loss, and indeed the pathologic appearance of microinfarcts is consistent with that of known ischemic infarctions.\nsynonyms :\n'}


{'id': 'HP_0025715', 'url': 'http://purl.obolibrary.org/obo/HP_0025715', 'lbl': 'Abnormal umbilical artery doppler waveform during pregnancy', 'desc': 'label: Abnormal umbilical artery doppler waveform during pregnancy\ndefinition : Abnormal waveforms the Doppler sonographic examination of bloodflow in the umbilical artery. vUmbilical arterial Doppler assessment is used in surveillance of fetal health in the third trimester.\nsynonyms :\n'}


{'id': 'HP_0025716', 'url': 'http://purl.obolibrary.org/obo/HP_0025716', 'lbl': 'Fetal anemia', 'desc': 'label: Fetal anemia\ndefinition : Low hemoglobin/hematocrit in a fetus as evidenced by percutaneous umbilical cord sampling and Doppler ultrasonographic assessment of the peak velocity of systolic blood flow in the middle cerebral artery.\nsynonyms :\n'}


{'id': 'HP_0025717', 'url': 'http://purl.obolibrary.org/obo/HP_0025717', 'lbl': 'Skeletal muscle autophagosome accumulation', 'desc': 'label: Skeletal muscle autophagosome accumulation\ndefinition : Abnormal accumulation of autophagosomes in skeletal muscle tissue.\nsynonyms :Autophagic material in muscle biopsy\n'}


{'id': 'HP_0025718', 'url': 'http://purl.obolibrary.org/obo/HP_0025718', 'lbl': 'Skeletal muscle hyperechogenicity', 'desc': 'label: Skeletal muscle hyperechogenicity\ndefinition : An increased echo intensity of muscle tissue on sonography, defined as an increased amount of returning echoes per square area of muscle tissue. On cross-section, normal muscle appears as a relatively anechoic structure with hyperechoic speckles within the tissue representing perimysial septa, giving it a starry night appearance. The boundaries of each muscle are delineated by the presence of hyperechoic fascia. In muscle disorders, one of the hallmark findings is replacement of healthy muscle with fat and fibrosis, manifested by an increase in echogenicity from higher sound transitions in the muscle. This increase in echogenicity is most distinct in conditions that lead to chronic pathology, such as long-standing muscle inflammation, dystrophy, or denervation.\nsynonyms :Hyperechoic muscle; Muscle ultrasound hyperechogenicity\n'}


{'id': 'HP_0025719', 'url': 'http://purl.obolibrary.org/obo/HP_0025719', 'lbl': 'Maternal vascular malperfusion', 'desc': 'label: Maternal vascular malperfusion\ndefinition : Gross findings of maternal vascular malperfusion include placental hypoplasia, placental infarction, and retroplacental hemorrhage. If information is available, it is preferable to annotate using the HPO terms that corresponding to the specific abnormalities.\nsynonyms :\n'}


{'id': 'HP_0025720', 'url': 'http://purl.obolibrary.org/obo/HP_0025720', 'lbl': 'Limited horizontal extraocular movement', 'desc': 'label: Limited horizontal extraocular movement\ndefinition : Limited mobility of the eye to move from side to side (horizontally) within its socket.\nsynonyms :\n'}


{'id': 'HP_0025721', 'url': 'http://purl.obolibrary.org/obo/HP_0025721', 'lbl': 'Limited vertical extraocular movement', 'desc': 'label: Limited vertical extraocular movement\ndefinition : Limited mobility of the eye to move up and down (vertically) within its socket.\nsynonyms :\n'}


{'id': 'HP_0025722', 'url': 'http://purl.obolibrary.org/obo/HP_0025722', 'lbl': 'Cerebral infarct', 'desc': 'label: Cerebral infarct\ndefinition : A necrotic lesion in the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors.\nsynonyms :\n'}


{'id': 'HP_0025723', 'url': 'http://purl.obolibrary.org/obo/HP_0025723', 'lbl': 'Abnormal fetal skin morphology', 'desc': 'label: Abnormal fetal skin morphology\ndefinition : Any structural anomaly of the skin of the fetus or newborn. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes.\nsynonyms :\n'}


{'id': 'HP_0025724', 'url': 'http://purl.obolibrary.org/obo/HP_0025724', 'lbl': 'Caseous vernix-like desquamation', 'desc': "label: Caseous vernix-like desquamation\ndefinition : Vernix caseosa is a physiological, viscous biofilm that is produced by desquamated fetal skin and sebaceous glands covering the fetus at the third trimester in-utero. The substance's gross morphology in post-partum is described by the etymology, as vernix means varnish, and caseosa means cheesy-like matter. This finding refers to an abnormally thick and greasy vernix caseosa-like scale present at birth.\nsynonyms :Greasy, thick vernix caseosa-like scale\n"}


{'id': 'HP_0025725', 'url': 'http://purl.obolibrary.org/obo/HP_0025725', 'lbl': 'Type 1 congenital pulmonary airway malformation', 'desc': 'label: Type 1 congenital pulmonary airway malformation\ndefinition : A type of congenital pulmonary airway malformation that is characterized by multiple large cysts or a single dominant cyst.\nsynonyms :\n'}


{'id': 'HP_0025726', 'url': 'http://purl.obolibrary.org/obo/HP_0025726', 'lbl': 'Type 2 congenital pulmonary airway malformation', 'desc': 'label: Type 2 congenital pulmonary airway malformation\ndefinition : A type of congenital pulmonary airway malformation that is characterized by multiple evenly spaced cysts (sponge-like appearance).\nsynonyms :\n'}


{'id': 'HP_0025727', 'url': 'http://purl.obolibrary.org/obo/HP_0025727', 'lbl': 'Type 3 congenital pulmonary airway malformation', 'desc': 'label: Type 3 congenital pulmonary airway malformation\ndefinition : A type of congenital pulmonary airway malformation that is characterized by a bulky firm mass with an adenomatoid appearance.\nsynonyms :\n'}


{'id': 'HP_0025728', 'url': 'http://purl.obolibrary.org/obo/HP_0025728', 'lbl': 'Periventricular pseudocyst', 'desc': 'label: Periventricular pseudocyst\ndefinition : Pseudocysts that lack an epithelial lining, PVPCs are frequently observed in the caudothalamic groove or in the infero-lateral aspect of the frontal horns of the lateral ventricles, but may also be located elsewhere along the periventricular germinal matrix, as in the temporal or occipital horns.\nsynonyms :\n'}


{'id': 'HP_0025729', 'url': 'http://purl.obolibrary.org/obo/HP_0025729', 'lbl': 'Fetal vascular malperfusion', 'desc': 'label: Fetal vascular malperfusion\ndefinition : The term fetal vascular malperfusion (FVM) is used to describe placental pathology that is throught to result from an obstruction in fetal blood flow that could result from a number of conditions (eg, umbilical cord lesions, hypercoagulability, complications of fetal cardiac dysfunction, such as hypoxia, etc.).\nsynonyms :\n'}


{'id': 'HP_0025730', 'url': 'http://purl.obolibrary.org/obo/HP_0025730', 'lbl': 'Foramen ovale aneurysm', 'desc': 'label: Foramen ovale aneurysm\ndefinition : Foramen ovale aneurysm (FOA) or atrial septal aneurysm is abnormal redundancy of the atrial septum primum, with bulging of the septum by at least half the width of the atrial chamber, or by at least 10 mm beyond the level of the atrial septum. The abnormal protrusion of the interatrial septum results in decreased left atrial volume. On color Doppler there is reduced left ventricular inflow.\nsynonyms :Fetal atrial septal dilatation; Redundant septum primum flap\n'}


{'id': 'HP_0030000', 'url': 'http://purl.obolibrary.org/obo/HP_0030000', 'lbl': 'EMG: repetitive nerve stimulation abnormality', 'desc': 'label: EMG: repetitive nerve stimulation abnormality\ndefinition : Abnormality observed upon electromyography when nerve studied is electrically stimulated six to ten times at 2 or 3 Hertz.\nsynonyms :\n'}


{'id': 'HP_0030001', 'url': 'http://purl.obolibrary.org/obo/HP_0030001', 'lbl': 'Lagophthalmos', 'desc': 'label: Lagophthalmos\ndefinition : A condition in which the eyelids do not close to cover the eye completely.\nsynonyms :Eyelids stay open; Inability to close the eyelids\n'}


{'id': 'HP_0030002', 'url': 'http://purl.obolibrary.org/obo/HP_0030002', 'lbl': 'Nocturnal lagophthalmos', 'desc': 'label: Nocturnal lagophthalmos\ndefinition : The inability to close the eyelids during sleep.\nsynonyms :Eyelids stay open at night; Inability to close the eyelids at night\n'}


{'id': 'HP_0030003', 'url': 'http://purl.obolibrary.org/obo/HP_0030003', 'lbl': 'Paralytic lagophthalmos', 'desc': 'label: Paralytic lagophthalmos\ndefinition : A type of lagophthalmos that occurs in association with facial nerve palsy.\nsynonyms :\n'}


{'id': 'HP_0030004', 'url': 'http://purl.obolibrary.org/obo/HP_0030004', 'lbl': 'Cicatricial lagophthalmos', 'desc': 'label: Cicatricial lagophthalmos\ndefinition : A type of lagophthalmos that occurs following trauma or surgery.\nsynonyms :Eyelids stay open due to scarring; Inability to close the eyelids due to scarring\n'}


{'id': 'HP_0030005', 'url': 'http://purl.obolibrary.org/obo/HP_0030005', 'lbl': 'Capillary leak', 'desc': 'label: Capillary leak\ndefinition : An acute phenomenon characterized by hypotension and anasarca due to the loss of plasma volume into peripheral tissues, with evidence of decreased plasma volume (hemoconcentration) and protein loss from the intravascular space (hypoalbuminemia) during acute episodes.\nsynonyms :Increased capillary permeability; Systemic capillary leak syndrome\n'}


{'id': 'HP_0030006', 'url': 'http://purl.obolibrary.org/obo/HP_0030006', 'lbl': 'Single fiber EMG abnormality', 'desc': 'label: Single fiber EMG abnormality\ndefinition : Abnormality in single fiber EMG recording, a technique that allows identification of action potentials (APs) from individual muscle fibers.\nsynonyms :Single fibre EMG abnormality\n'}


{'id': 'HP_0030007', 'url': 'http://purl.obolibrary.org/obo/HP_0030007', 'lbl': 'EMG: positive sharp waves', 'desc': 'label: EMG: positive sharp waves\ndefinition : These are spontaneous firing action potentials stimulated by needle movement of an injured muscle fiber. There is propagation to, but not past, the needle tip. This inhibits the display of the negative deflection of the waveform.\nsynonyms :\n'}


{'id': 'HP_0030008', 'url': 'http://purl.obolibrary.org/obo/HP_0030008', 'lbl': 'Cervical agenesis', 'desc': 'label: Cervical agenesis\ndefinition : Congenital absence of the cervix.\nsynonyms :Absent cervix; Aplasia of the cervix; Cervical aplasia\n'}


{'id': 'HP_0030009', 'url': 'http://purl.obolibrary.org/obo/HP_0030009', 'lbl': 'Cervical insufficiency', 'desc': 'label: Cervical insufficiency\ndefinition : A cervix that shows a painless dilation and shortening during the second trimester of pregnancy with resultant recurrent pregnancy loss or delivery is considered incompetent\nsynonyms :Incompetent cervix\n'}


{'id': 'HP_0030010', 'url': 'http://purl.obolibrary.org/obo/HP_0030010', 'lbl': 'Hydrometrocolpos', 'desc': 'label: Hydrometrocolpos\ndefinition : Hydrometrocolpos is an accumulation of uterine and vaginal secretions as well as menstrual blood in the uterus and vagina.\nsynonyms :\n'}


{'id': 'HP_0030011', 'url': 'http://purl.obolibrary.org/obo/HP_0030011', 'lbl': 'Imperforate hymen', 'desc': 'label: Imperforate hymen\ndefinition : A congenital disorder where the hymen (a membrane that surrounds or partially covers the external vaginal opening) does not have an opening and completely obstructs the vagina.\nsynonyms :\n'}


{'id': 'HP_0030012', 'url': 'http://purl.obolibrary.org/obo/HP_0030012', 'lbl': 'Abnormal female reproductive system physiology', 'desc': 'label: Abnormal female reproductive system physiology\ndefinition : \nsynonyms :Abnormal female reproductive system physiology; Abnormal female genital system physiology\n'}


{'id': 'HP_0030013', 'url': 'http://purl.obolibrary.org/obo/HP_0030013', 'lbl': 'obsolete Endometriosis', 'desc': 'label: obsolete Endometriosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030014', 'url': 'http://purl.obolibrary.org/obo/HP_0030014', 'lbl': 'Female sexual dysfunction', 'desc': 'label: Female sexual dysfunction\ndefinition : A problem occurring during any phase of the female sexual response cycle that prevents the individual from experiencing satisfaction from the sexual activity\nsynonyms :\n'}


{'id': 'HP_0030015', 'url': 'http://purl.obolibrary.org/obo/HP_0030015', 'lbl': 'Female anorgasmia', 'desc': 'label: Female anorgasmia\ndefinition : The persistent of recurrent difficulty, delay in, or absence of attaining orgasm following sufficient sexual stimulation and arousal.\nsynonyms :Female orgasmic disorder\n'}


{'id': 'HP_0030016', 'url': 'http://purl.obolibrary.org/obo/HP_0030016', 'lbl': 'Dyspareunia', 'desc': 'label: Dyspareunia\ndefinition : Recurrent or persistent genital pain associated with sexual intercourse.\nsynonyms :\n'}


{'id': 'HP_0030017', 'url': 'http://purl.obolibrary.org/obo/HP_0030017', 'lbl': 'Vaginismus', 'desc': 'label: Vaginismus\ndefinition : Recurrent or persistent involuntary spasms of the musculature of the outer third of the vagina that interferes with vaginal penetration, and which causes personal distress.\nsynonyms :Myalgia of pelvic floor; Pelvic floor myalgia\n'}


{'id': 'HP_0030018', 'url': 'http://purl.obolibrary.org/obo/HP_0030018', 'lbl': 'Decreased female libido', 'desc': 'label: Decreased female libido\ndefinition : Dminished sexual desire in female.\nsynonyms :Decreased female sex drive\n'}


{'id': 'HP_0030019', 'url': 'http://purl.obolibrary.org/obo/HP_0030019', 'lbl': 'Increased female libido', 'desc': 'label: Increased female libido\ndefinition : Elevated sexual desire in female\nsynonyms :Increased female sex drive\n'}


{'id': 'HP_0030021', 'url': 'http://purl.obolibrary.org/obo/HP_0030021', 'lbl': 'Auricular tag', 'desc': 'label: Auricular tag\ndefinition : Small protrusion within the pinna.\nsynonyms :\n'}


{'id': 'HP_0030022', 'url': 'http://purl.obolibrary.org/obo/HP_0030022', 'lbl': 'Question mark ear', 'desc': 'label: Question mark ear\ndefinition : Cleft between the helix and the lobe.\nsynonyms :Constricted ear; Cosman ear; Question mark ear; Question mark ears\n'}


{'id': 'HP_0030023', 'url': 'http://purl.obolibrary.org/obo/HP_0030023', 'lbl': 'Quelprud nodule', 'desc': 'label: Quelprud nodule\ndefinition : Small cartilaginous prominence on the posterior concha.\nsynonyms :\n'}


{'id': 'HP_0030024', 'url': 'http://purl.obolibrary.org/obo/HP_0030024', 'lbl': 'Pretragal ectopia', 'desc': 'label: Pretragal ectopia\ndefinition : Variably shaped, cartilage-containing tissue anterior to the external auditory meatus.\nsynonyms :Extra cartilage in front of the ear; Accessory Tragus; Pretragal Duplication\n'}


{'id': 'HP_0030025', 'url': 'http://purl.obolibrary.org/obo/HP_0030025', 'lbl': 'Auricular pit', 'desc': 'label: Auricular pit\ndefinition : Small indentation in the lower part of the ascending helix, concha, or in the crus helix.\nsynonyms :\n'}


{'id': 'HP_0030026', 'url': 'http://purl.obolibrary.org/obo/HP_0030026', 'lbl': 'Squared superior portion of helix', 'desc': 'label: Squared superior portion of helix\ndefinition : Flattening instead of curving or rounded superior helix, allowing the superior helix to run more horizontally than usual.\nsynonyms :\n'}


{'id': 'HP_0030027', 'url': 'http://purl.obolibrary.org/obo/HP_0030027', 'lbl': 'Abnormal nasal cartilage morphology', 'desc': 'label: Abnormal nasal cartilage morphology\ndefinition : A morphological anomaly of the nasal cartilage.\nsynonyms :Abnormality of cartilage of nose; Abnormality of the nasal cartilage; Anomaly of cartilage of nose; Anomaly of nasal cartilage; Deformity of cartilage of nose; Deformity of nasal cartilage; Malformation of cartilage of nose; Malformation of nasal cartilage\n'}


{'id': 'HP_0030028', 'url': 'http://purl.obolibrary.org/obo/HP_0030028', 'lbl': 'Absent nasal cartilage', 'desc': 'label: Absent nasal cartilage\ndefinition : Lack of a palpable nasal cartilage.\nsynonyms :Absent cartilage of nose; Absent nasal cartilage; Agenesis of cartilage of nose; Agenesis of nasal cartilage; Failure of development of cartilage of nose; Failure of development of nasal cartilage; Missing cartilage of nose; Missing nasal cartilage\n'}


{'id': 'HP_0030029', 'url': 'http://purl.obolibrary.org/obo/HP_0030029', 'lbl': 'Splayed fingers', 'desc': 'label: Splayed fingers\ndefinition : Divergence of digits along the A/P axis (in the plane of the palm).\nsynonyms :Splayed fingers; Spreading of the fingers\n'}


{'id': 'HP_0030030', 'url': 'http://purl.obolibrary.org/obo/HP_0030030', 'lbl': 'Absent ray', 'desc': 'label: Absent ray\ndefinition : The absence of all phalanges of a digit and the associated metacarpal /metatarsal.\nsynonyms :\n'}


{'id': 'HP_0030031', 'url': 'http://purl.obolibrary.org/obo/HP_0030031', 'lbl': 'Small toe', 'desc': 'label: Small toe\ndefinition : Significant reduction in both length and girth of the toe compared to the contralateral toe, or alternatively, compared to a typical toe size for an age-matched individual.\nsynonyms :Small toe\n'}


{'id': 'HP_0030032', 'url': 'http://purl.obolibrary.org/obo/HP_0030032', 'lbl': 'Partial absence of foot', 'desc': 'label: Partial absence of foot\ndefinition : An incomplete absence of the foot, with no bony elements distal to the tarsals, but with preservation of some or all of the tarsals.\nsynonyms :Partial absence of foot\n'}


{'id': 'HP_0030033', 'url': 'http://purl.obolibrary.org/obo/HP_0030033', 'lbl': 'Small finger', 'desc': 'label: Small finger\ndefinition : Significant reduction in both length and girth of the finger compared to the contralateral finger, or alternatively, compared to a typical finger size for an age-matched individual.\nsynonyms :Small finger\n'}


{'id': 'HP_0030034', 'url': 'http://purl.obolibrary.org/obo/HP_0030034', 'lbl': 'Glomerular basement membrane lamellation', 'desc': 'label: Glomerular basement membrane lamellation\ndefinition : Presence of abnormal additional layers of the basement membrane of the glomerulus.\nsynonyms :Lamellated/basket-woven thickened glomerular basement membranes; Lamellation of the glomerular basement membrane\n'}


{'id': 'HP_0030035', 'url': 'http://purl.obolibrary.org/obo/HP_0030035', 'lbl': 'Struvite nephrolithiasis', 'desc': 'label: Struvite nephrolithiasis\ndefinition : Presence of struvite (magnesium ammonium phosphate) containing calculi (kidney stones).\nsynonyms :Struvite kidney stones\n'}


{'id': 'HP_0030036', 'url': 'http://purl.obolibrary.org/obo/HP_0030036', 'lbl': 'Isothenuria', 'desc': 'label: Isothenuria\ndefinition : Inability of the kidneys to produce either concentrated or dilute urine.\nsynonyms :\n'}


{'id': 'HP_0030037', 'url': 'http://purl.obolibrary.org/obo/HP_0030037', 'lbl': 'Bifid ureter', 'desc': 'label: Bifid ureter\ndefinition : Incomplete duplication of the ureter.\nsynonyms :\n'}


{'id': 'HP_0030038', 'url': 'http://purl.obolibrary.org/obo/HP_0030038', 'lbl': 'Enchondroma', 'desc': 'label: Enchondroma\ndefinition : A solitary, benign, intramedullary cartilage tumor that is often found in the short tubular bones of the hands and feet, distal femur, and proximal humerus.\nsynonyms :\n'}


{'id': 'HP_0030039', 'url': 'http://purl.obolibrary.org/obo/HP_0030039', 'lbl': 'Fused thoracic vertebrae', 'desc': 'label: Fused thoracic vertebrae\ndefinition : A congenital anomaly characterized by a joining (fusion) of two or more thoracic vertebral bodies with one another.\nsynonyms :\n'}


{'id': 'HP_0030040', 'url': 'http://purl.obolibrary.org/obo/HP_0030040', 'lbl': 'Fused lumbar vertebrae', 'desc': 'label: Fused lumbar vertebrae\ndefinition : A congenital anomaly characterized by a joining (fusion) of two or more lumbar vertebral bodies with one another.\nsynonyms :\n'}


{'id': 'HP_0030041', 'url': 'http://purl.obolibrary.org/obo/HP_0030041', 'lbl': "Schmorl's node", 'desc': "label: Schmorl's node\ndefinition : A Schmorl's node is the herniation of nucleus pulposus through the cartilaginous and bony end plate into the body of the adjacent vertebra.\nsynonyms :Schmorl's nodes\n"}


{'id': 'HP_0030042', 'url': 'http://purl.obolibrary.org/obo/HP_0030042', 'lbl': 'Incomplete ossification of pubis', 'desc': 'label: Incomplete ossification of pubis\ndefinition : Failure to complete ossification (maturation and calcification) of the pubic bone.\nsynonyms :Incomplete maturation of the pubic bone\n'}


{'id': 'HP_0030043', 'url': 'http://purl.obolibrary.org/obo/HP_0030043', 'lbl': 'Hip subluxation', 'desc': 'label: Hip subluxation\ndefinition : A partial dislocation of the hip joint, whereby the head of the femur is partially displaced from the socket.\nsynonyms :Partial hip dislocation; Subluxation involving the hip joint\n'}


{'id': 'HP_0030044', 'url': 'http://purl.obolibrary.org/obo/HP_0030044', 'lbl': 'Flexion contracture of digit', 'desc': 'label: Flexion contracture of digit\ndefinition : A bent (flexed) finger or toe joint that cannot be straightened actively or passively. It is thus a chronic loss of joint motion due to structural changes in muscle, tendons, ligaments, or skin that prevents normal movement of joints.\nsynonyms :\n'}


{'id': 'HP_0030045', 'url': 'http://purl.obolibrary.org/obo/HP_0030045', 'lbl': 'Serpentine fibula', 'desc': 'label: Serpentine fibula\ndefinition : Elongated curved (S-shaped) fibulae.\nsynonyms :S-shaped calf bone\n'}


{'id': 'HP_0030046', 'url': 'http://purl.obolibrary.org/obo/HP_0030046', 'lbl': 'Hypoglycosylation of alpha-dystroglycan', 'desc': 'label: Hypoglycosylation of alpha-dystroglycan\ndefinition : A reduction in the degree of glycosylation of alpha-dystroglycan in muscle tissue.\nsynonyms :\n'}