{'id': 'HP_0011726', 'url': 'http://purl.obolibrary.org/obo/HP_0011726', 'lbl': 'Persistent fetal circulation', 'desc': 'label: Persistent fetal circulation\ndefinition : Systemic desaturation of a liveborn baby resulting from persistent pulmonary hypertension with a patent ductus arteriosus and patent foramen ovale, such that the circulation in postnatal life follows the fetal course.\nsynonyms :Persistent foetal circulation\n'}


{'id': 'HP_0011727', 'url': 'http://purl.obolibrary.org/obo/HP_0011727', 'lbl': 'Peroneal muscle weakness', 'desc': 'label: Peroneal muscle weakness\ndefinition : Weakness of the peroneal muscles.\nsynonyms :Fibularis muscle weakness\n'}


{'id': 'HP_0011728', 'url': 'http://purl.obolibrary.org/obo/HP_0011728', 'lbl': 'Elbow clonus', 'desc': 'label: Elbow clonus\ndefinition : Clonus at the elbow joint, i.e., an exaggerated phasic stretch reflex characterized by repetitive, rhythmic contractions at the elbow, generated by rapid passive stretch at the elbow joint.\nsynonyms :\n'}


{'id': 'HP_0011729', 'url': 'http://purl.obolibrary.org/obo/HP_0011729', 'lbl': 'Abnormality of joint mobility', 'desc': 'label: Abnormality of joint mobility\ndefinition : An abnormality in the range and ease of motion of joints across their normal range.\nsynonyms :\n'}


{'id': 'HP_0011730', 'url': 'http://purl.obolibrary.org/obo/HP_0011730', 'lbl': 'Abnormal central sensory function', 'desc': 'label: Abnormal central sensory function\ndefinition : An abnormality of sensation related to CNS function. Assuming the primary sensory modalities are intact and the patient is alert and cooperative, the presence of an abnormality of sensory function may indicate a lesion of a parietal cortex, the thalamocortical projections to the parietal cortex, or the spinal cord.\nsynonyms :Abnormality of central sensory function\n'}


{'id': 'HP_0011731', 'url': 'http://purl.obolibrary.org/obo/HP_0011731', 'lbl': 'Abnormality of circulating cortisol level', 'desc': 'label: Abnormality of circulating cortisol level\ndefinition : An abnormality of the concentration of cortisol in the blood.\nsynonyms :\n'}


{'id': 'HP_0011732', 'url': 'http://purl.obolibrary.org/obo/HP_0011732', 'lbl': 'Abnormality of adrenal morphology', 'desc': 'label: Abnormality of adrenal morphology\ndefinition : Any structural anomaly of the adrenal glands.\nsynonyms :\n'}


{'id': 'HP_0011733', 'url': 'http://purl.obolibrary.org/obo/HP_0011733', 'lbl': 'Abnormality of adrenal physiology', 'desc': 'label: Abnormality of adrenal physiology\ndefinition : A functional abnormality of the adrenal glands.\nsynonyms :\n'}


{'id': 'HP_0011734', 'url': 'http://purl.obolibrary.org/obo/HP_0011734', 'lbl': 'Central adrenal insufficiency', 'desc': 'label: Central adrenal insufficiency\ndefinition : A form of adrenal insufficiency related to a lack of ACTH, which leads to a decrease in the production of cortisol by the adrenal glands. Aldosterone production is not usually affected.\nsynonyms :Secondary adrenal insufficiency\n'}


{'id': 'HP_0011735', 'url': 'http://purl.obolibrary.org/obo/HP_0011735', 'lbl': 'Adrenocorticotropin deficient adrenal insufficiency', 'desc': 'label: Adrenocorticotropin deficient adrenal insufficiency\ndefinition : Adrenal insufficiency secondary to a defect in ACTH production.\nsynonyms :ACTH deficient adrenal insufficiency\n'}


{'id': 'HP_0011736', 'url': 'http://purl.obolibrary.org/obo/HP_0011736', 'lbl': 'Primary hyperaldosteronism', 'desc': 'label: Primary hyperaldosteronism\ndefinition : A form of hyperaldosteronism caused by a defect within the adrenal gland.\nsynonyms :\n'}


{'id': 'HP_0011737', 'url': 'http://purl.obolibrary.org/obo/HP_0011737', 'lbl': 'Corticotropin-releasing hormone deficient adrenal insufficiency', 'desc': 'label: Corticotropin-releasing hormone deficient adrenal insufficiency\ndefinition : Adrenal insufficiency secondary to a defect in corticotropin-releasing hormone production.\nsynonyms :CRH deficient adrenal insufficiency; Tertiary adrenal insufficiency\n'}


{'id': 'HP_0011738', 'url': 'http://purl.obolibrary.org/obo/HP_0011738', 'lbl': 'Corticotropin-releasing hormone receptor defect', 'desc': 'label: Corticotropin-releasing hormone receptor defect\ndefinition : Adrenal insufficiency secondary to a defect in the corticotropin-releasing hormone receptor.\nsynonyms :CRHR defect; Corticotropin-releasing hormone receptor (CRHR) resistance\n'}


{'id': 'HP_0011739', 'url': 'http://purl.obolibrary.org/obo/HP_0011739', 'lbl': 'Dexamethasone-suppressible primary hyperaldosteronism', 'desc': 'label: Dexamethasone-suppressible primary hyperaldosteronism\ndefinition : A form of primary hyperaldosteronism in which the overproduction of aldosterone can be suppressed by the administration of dexamethasone.\nsynonyms :Familial primary hyperaldosteronism type 1; Glucocorticoid-remediable familial primary aldosteronism\n'}


{'id': 'HP_0011740', 'url': 'http://purl.obolibrary.org/obo/HP_0011740', 'lbl': 'Glucocortocoid-insensitive primary hyperaldosteronism', 'desc': 'label: Glucocortocoid-insensitive primary hyperaldosteronism\ndefinition : A form of primary hyperaldosteronism in which the overproduction of aldosterone cannot be suppressed by the administration of dexamethasone or similar glucocorticoids.\nsynonyms :Familial primary hyperaldosteronism type 2\n'}


{'id': 'HP_0011741', 'url': 'http://purl.obolibrary.org/obo/HP_0011741', 'lbl': 'Secondary hyperaldosteronism', 'desc': 'label: Secondary hyperaldosteronism\ndefinition : A form of hyperaldosteronism caused by abnormally increased renin levels.\nsynonyms :Hyperreninemic hyperaldosteronism\n'}


{'id': 'HP_0011742', 'url': 'http://purl.obolibrary.org/obo/HP_0011742', 'lbl': 'Ectopic adrenal gland', 'desc': 'label: Ectopic adrenal gland\ndefinition : Abnormal anatomical location of the adrenal gland.\nsynonyms :Abnormal adrenal gland position\n'}


{'id': 'HP_0011743', 'url': 'http://purl.obolibrary.org/obo/HP_0011743', 'lbl': 'Adrenal gland agenesis', 'desc': 'label: Adrenal gland agenesis\ndefinition : Absent development of the adrenal gland.\nsynonyms :\n'}


{'id': 'HP_0011744', 'url': 'http://purl.obolibrary.org/obo/HP_0011744', 'lbl': 'Secondary hypercortisolism', 'desc': 'label: Secondary hypercortisolism\ndefinition : Hypercortisolemia associated with a overproduction of ACTH (often from a tumor), leading secondarily to overproduction of cortisol.\nsynonyms :ACTH-dependent hypercortisolemia\n'}


{'id': 'HP_0011745', 'url': 'http://purl.obolibrary.org/obo/HP_0011745', 'lbl': 'Non-secretory adrenocortical adenoma', 'desc': 'label: Non-secretory adrenocortical adenoma\ndefinition : An hormonally inactive adrenocortical adenoma, that is, an adenoma that does not secrete excessive amounts of adrenal hormones.\nsynonyms :Non-secretory adrenal adenoma\n'}


{'id': 'HP_0011746', 'url': 'http://purl.obolibrary.org/obo/HP_0011746', 'lbl': 'Secretory adrenocortical adenoma', 'desc': 'label: Secretory adrenocortical adenoma\ndefinition : An hormonally active adrenocortical adenoma, that is, an adenoma that secretes excessive amounts of adrenal hormones.\nsynonyms :Secretory adrenal adenoma\n'}


{'id': 'HP_0011747', 'url': 'http://purl.obolibrary.org/obo/HP_0011747', 'lbl': 'Abnormality of the anterior pituitary', 'desc': 'label: Abnormality of the anterior pituitary\ndefinition : An abnormality of the adenohypophysis, which is also known as the anterior lobe of the pituitary gland.\nsynonyms :Pituitary disease\n'}


{'id': 'HP_0011748', 'url': 'http://purl.obolibrary.org/obo/HP_0011748', 'lbl': 'Adrenocorticotropic hormone deficiency', 'desc': 'label: Adrenocorticotropic hormone deficiency\ndefinition : A reduced ability to secrete adrenocorticotropic hormone (ACTH), a hormone that stimulates the adrenal cortex to secrete of glucocorticoids such as cortisol.\nsynonyms :ACTH deficiency; Corticotropin deficiency\n'}


{'id': 'HP_0011749', 'url': 'http://purl.obolibrary.org/obo/HP_0011749', 'lbl': 'Adrenocorticotropic hormone excess', 'desc': 'label: Adrenocorticotropic hormone excess\ndefinition : Overproduction of adrenocorticotropic hormone (ACTH), which generally leads secondarily to overproduction of cortisol by the adrenal cortex.\nsynonyms :ACTH excess\n'}


{'id': 'HP_0011750', 'url': 'http://purl.obolibrary.org/obo/HP_0011750', 'lbl': 'Neoplasm of the anterior pituitary', 'desc': 'label: Neoplasm of the anterior pituitary\ndefinition : A tumor (abnormal growth of tissue) of the adenohypophysis, which is also known as the anterior lobe of the pituitary gland.\nsynonyms :Neoplasm of the adenohypophysis; Neoplasm of the pars anterior\n'}


{'id': 'HP_0011751', 'url': 'http://purl.obolibrary.org/obo/HP_0011751', 'lbl': 'Abnormality of the posterior pituitary', 'desc': 'label: Abnormality of the posterior pituitary\ndefinition : An abnormality of the neurohypophysis, which is also known as the posterior lobe of the hypophysis.\nsynonyms :Abnormality of the neurohypophysis\n'}


{'id': 'HP_0011752', 'url': 'http://purl.obolibrary.org/obo/HP_0011752', 'lbl': 'Neoplasm of the posterior pituitary', 'desc': 'label: Neoplasm of the posterior pituitary\ndefinition : The presence of a neoplasm (tumor) in the neurohypophysis, which is also known as the posterior lobe of the hypophysis.\nsynonyms :Neoplasm of the neurohypophysis\n'}


{'id': 'HP_0011753', 'url': 'http://purl.obolibrary.org/obo/HP_0011753', 'lbl': 'Posterior pituitary dysgenesis', 'desc': 'label: Posterior pituitary dysgenesis\ndefinition : Abnormal development of the neurohypophysis during embryonic growth and development.\nsynonyms :Neurohypophysis dysplasia; Posterior pituitary dysplasia\n'}


{'id': 'HP_0011754', 'url': 'http://purl.obolibrary.org/obo/HP_0011754', 'lbl': 'Pituicytoma', 'desc': 'label: Pituicytoma\ndefinition : A solid, low grade, spindle cell, glial neoplasm of adults that originates in the neurohypophysis or infundibulum. Clinical signs and symptoms include visual disturbance, headache and features of hypopituitarism. Pituicytomas are well-circumscribed, solid masses that can measure up to several centimeters. Histologically, they show a compact architecture consisting of elongate, bipolar spindle cells arranged in interlacing fascicles or assuming a storiform pattern.\nsynonyms :\n'}


{'id': 'HP_0011755', 'url': 'http://purl.obolibrary.org/obo/HP_0011755', 'lbl': 'Ectopic posterior pituitary', 'desc': 'label: Ectopic posterior pituitary\ndefinition : An abnormal anatomical location of the posterior lobe of the hypophysis, also known as the neurohypophysis. The posterior pituitary is normally present in the dorsal portion of the sella turcica, but when ectopic is usually near the median eminence. This defect is likely to be due to abnormal migration during embryogenesis.\nsynonyms :Ectopic neurohypophysis\n'}


{'id': 'HP_0011756', 'url': 'http://purl.obolibrary.org/obo/HP_0011756', 'lbl': 'Posterior pituitary agenesis', 'desc': 'label: Posterior pituitary agenesis\ndefinition : Absence of the neurohypophysis owing to a developmental defect.\nsynonyms :Neurohypophysis agenesis\n'}


{'id': 'HP_0011757', 'url': 'http://purl.obolibrary.org/obo/HP_0011757', 'lbl': 'Posterior pituitary hypoplasia', 'desc': 'label: Posterior pituitary hypoplasia\ndefinition : Underdevelopment of the neurohypophysis.\nsynonyms :Neurohypophysis hypoplasia\n'}


{'id': 'HP_0011758', 'url': 'http://purl.obolibrary.org/obo/HP_0011758', 'lbl': 'Pituitary acidophilic stem cell adenoma', 'desc': 'label: Pituitary acidophilic stem cell adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011759', 'url': 'http://purl.obolibrary.org/obo/HP_0011759', 'lbl': 'Pituitary gonadotropic cell adenoma', 'desc': 'label: Pituitary gonadotropic cell adenoma\ndefinition : A type of pituitary adenoma that produces gonadotropins.\nsynonyms :Pituitary gonadotropinoma\n'}


{'id': 'HP_0011760', 'url': 'http://purl.obolibrary.org/obo/HP_0011760', 'lbl': 'Pituitary growth hormone cell adenoma', 'desc': 'label: Pituitary growth hormone cell adenoma\ndefinition : A type of pituitary adenoma that produces growth hormone.\nsynonyms :Pituitary somatotropinoma\n'}


{'id': 'HP_0011761', 'url': 'http://purl.obolibrary.org/obo/HP_0011761', 'lbl': 'Pituitary null cell adenoma', 'desc': 'label: Pituitary null cell adenoma\ndefinition : A type of pituitary adenoma that is of unknown cellular origin and that lacks immunocytochemical or fine structural markers. Null cell adenomas are not associated with hormone excess.\nsynonyms :Clinically silent pituitary adenoma; Hormonally silent pituitary adenoma; Non-functional pituitary adenoma; Silent pituitary adenoma\n'}


{'id': 'HP_0011762', 'url': 'http://purl.obolibrary.org/obo/HP_0011762', 'lbl': 'Pituitary thyrotropic cell adenoma', 'desc': 'label: Pituitary thyrotropic cell adenoma\ndefinition : A type of pituitary adenoma that produces thyroid stimulating hormone (TSH).\nsynonyms :Pituitary thyrotropinoma\n'}


{'id': 'HP_0011763', 'url': 'http://purl.obolibrary.org/obo/HP_0011763', 'lbl': 'Pituitary carcinoma', 'desc': 'label: Pituitary carcinoma\ndefinition : A pituitary tumor with subarachnoid, brain, or systemic metastasis. The diagnosis of a pituitary carcinoma requires evidence of metastatic disease, either outside the central nervous system (CNS) or as separate noncontiguous foci within the CNS.\nsynonyms :\n'}


{'id': 'HP_0011764', 'url': 'http://purl.obolibrary.org/obo/HP_0011764', 'lbl': 'Pituitary spindle cell oncocytoma', 'desc': 'label: Pituitary spindle cell oncocytoma\ndefinition : A spindled-to-epithelioid, oncocytic, nonendocrine neoplasm of the anterior hypophysis that manifests in adults and follows a benign clinical course. Pituitary spindle cell oncocytomas are firm, fibrous, and adherent to surrounding structures and are highly vascular.\nsynonyms :\n'}


{'id': 'HP_0011765', 'url': 'http://purl.obolibrary.org/obo/HP_0011765', 'lbl': 'obsolete Ectopic anterior pituitary', 'desc': 'label: obsolete Ectopic anterior pituitary\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011766', 'url': 'http://purl.obolibrary.org/obo/HP_0011766', 'lbl': 'Abnormality of the parathyroid morphology', 'desc': 'label: Abnormality of the parathyroid morphology\ndefinition : A structural abnormality of the parathyroid gland.\nsynonyms :\n'}


{'id': 'HP_0011767', 'url': 'http://purl.obolibrary.org/obo/HP_0011767', 'lbl': 'Abnormality of the parathyroid physiology', 'desc': 'label: Abnormality of the parathyroid physiology\ndefinition : A functional abnormality of the parathyroid gland.\nsynonyms :Parathyroid issue; Parathyroid dysfunction\n'}


{'id': 'HP_0011768', 'url': 'http://purl.obolibrary.org/obo/HP_0011768', 'lbl': 'Parathyroid dysgenesis', 'desc': 'label: Parathyroid dysgenesis\ndefinition : Abnormal embryonic development of the parathyroid gland.\nsynonyms :\n'}


{'id': 'HP_0011769', 'url': 'http://purl.obolibrary.org/obo/HP_0011769', 'lbl': 'Ectopic parathyroid', 'desc': 'label: Ectopic parathyroid\ndefinition : An abnormal anatomical location of the parathyroid gland.\nsynonyms :\n'}


{'id': 'HP_0011770', 'url': 'http://purl.obolibrary.org/obo/HP_0011770', 'lbl': 'Tertiary hyperparathyroidism', 'desc': 'label: Tertiary hyperparathyroidism\ndefinition : A type of hyperparathyroidism that occurs following kidney transplantation, which is a treatment for secondary hyperparathyroidism. Although kidney transplantation leads to a normalization of serum calcium and parathyroid hormone in most patients. The state of persistent hypercalcemia and hyperparathyroidism is referred to as tertiary hyperparathyroidism.\nsynonyms :\n'}


{'id': 'HP_0011771', 'url': 'http://purl.obolibrary.org/obo/HP_0011771', 'lbl': 'Autoimmune hypoparathyroidism', 'desc': 'label: Autoimmune hypoparathyroidism\ndefinition : A type of hypoparathyroidism with circulating antiparathyroid or anti-calcium sensing receptor antibodies indicative of autoimmunity.\nsynonyms :\n'}


{'id': 'HP_0011772', 'url': 'http://purl.obolibrary.org/obo/HP_0011772', 'lbl': 'Abnormal thyroid morphology', 'desc': 'label: Abnormal thyroid morphology\ndefinition : A structural abnormality of the thyroid gland.\nsynonyms :Abnormal shape of thyroid gland; Abnormality of thyroid morphology\n'}


{'id': 'HP_0011773', 'url': 'http://purl.obolibrary.org/obo/HP_0011773', 'lbl': 'Uninodular goiter', 'desc': 'label: Uninodular goiter\ndefinition : Enlargement of the thyroid gland related to a singular nodule in the thyroid gland.\nsynonyms :Uninodular goitre\n'}


{'id': 'HP_0011774', 'url': 'http://purl.obolibrary.org/obo/HP_0011774', 'lbl': 'Thyroid follicular adenoma', 'desc': 'label: Thyroid follicular adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011775', 'url': 'http://purl.obolibrary.org/obo/HP_0011775', 'lbl': 'Thyroid macrofollicular adenoma', 'desc': 'label: Thyroid macrofollicular adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011776', 'url': 'http://purl.obolibrary.org/obo/HP_0011776', 'lbl': 'Thyroid microfollicular adenoma', 'desc': 'label: Thyroid microfollicular adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011777', 'url': 'http://purl.obolibrary.org/obo/HP_0011777', 'lbl': 'Thyroid papillary adenoma', 'desc': 'label: Thyroid papillary adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011778', 'url': 'http://purl.obolibrary.org/obo/HP_0011778', 'lbl': 'Thyroid atypical adenoma', 'desc': 'label: Thyroid atypical adenoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011779', 'url': 'http://purl.obolibrary.org/obo/HP_0011779', 'lbl': 'Anaplastic thyroid carcinoma', 'desc': 'label: Anaplastic thyroid carcinoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011780', 'url': 'http://purl.obolibrary.org/obo/HP_0011780', 'lbl': 'Thyroid hemiagenesis', 'desc': 'label: Thyroid hemiagenesis\ndefinition : Absence of a lobe of the thyroid gland related to a failure of its embryologic development.\nsynonyms :\n'}


{'id': 'HP_0011781', 'url': 'http://purl.obolibrary.org/obo/HP_0011781', 'lbl': 'Thyroid C cell hyperplasia', 'desc': 'label: Thyroid C cell hyperplasia\ndefinition : An abnormal growth of parafollicular (C-cells) cells.\nsynonyms :\n'}


{'id': 'HP_0011782', 'url': 'http://purl.obolibrary.org/obo/HP_0011782', 'lbl': 'Thyroid crisis', 'desc': 'label: Thyroid crisis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011783', 'url': 'http://purl.obolibrary.org/obo/HP_0011783', 'lbl': 'Thyrotoxicosis from ectopic thyroid tissue', 'desc': 'label: Thyrotoxicosis from ectopic thyroid tissue\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011784', 'url': 'http://purl.obolibrary.org/obo/HP_0011784', 'lbl': 'Thyrotoxicosis with diffuse goiter', 'desc': 'label: Thyrotoxicosis with diffuse goiter\ndefinition : \nsynonyms :Thyrotoxicosis with diffuse goitre\n'}


{'id': 'HP_0011785', 'url': 'http://purl.obolibrary.org/obo/HP_0011785', 'lbl': 'Thyrotoxicosis with toxic multinodular goiter', 'desc': 'label: Thyrotoxicosis with toxic multinodular goiter\ndefinition : \nsynonyms :Thyrotoxicosis with toxic multinodular goitre\n'}


{'id': 'HP_0011786', 'url': 'http://purl.obolibrary.org/obo/HP_0011786', 'lbl': 'Thyrotoxicosis with toxic single thyroid nodule', 'desc': 'label: Thyrotoxicosis with toxic single thyroid nodule\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0011787', 'url': 'http://purl.obolibrary.org/obo/HP_0011787', 'lbl': 'Central hypothyroidism', 'desc': 'label: Central hypothyroidism\ndefinition : A type of hypothyroidism due to an insufficient stimulation of an otherwise normal thyroid gland. Central hypothyroidism is caused by either pituitary (secondary hypothyroidism) or hypothalamic (tertiary hypothyroidism) defects.\nsynonyms :\n'}


{'id': 'HP_0011788', 'url': 'http://purl.obolibrary.org/obo/HP_0011788', 'lbl': 'Increased circulating free T3', 'desc': "label: Increased circulating free T3\ndefinition : An elevated concentration of free 3,3',5-triiodo-L-thyronine in the blood circulation.\nsynonyms :Increased circulating free triiodothyronine; Increased serum fT3; Increased serum free T3; Increased serum free triiodothyronine\n"}


{'id': 'HP_0011789', 'url': 'http://purl.obolibrary.org/obo/HP_0011789', 'lbl': 'Impaired sensitivity to thyroid stimulating hormone', 'desc': 'label: Impaired sensitivity to thyroid stimulating hormone\ndefinition : Reduced sensitivity of thyroid follicle cells to stimulation by biologically active thyroid-stimulating hormone (TSH).\nsynonyms :TSHR defect; Thyroid-stimulating hormone receptor defect\n'}


{'id': 'HP_0011790', 'url': 'http://purl.obolibrary.org/obo/HP_0011790', 'lbl': 'Activating thyroid-stimulating hormone receptor defect', 'desc': 'label: Activating thyroid-stimulating hormone receptor defect\ndefinition : Gain-of-function thyroid-stimulating hormone receptor (TSHR) defect.\nsynonyms :Activating TSHR defect\n'}


{'id': 'HP_0011791', 'url': 'http://purl.obolibrary.org/obo/HP_0011791', 'lbl': 'Inactivating thyroid-stimulating hormone receptor defect', 'desc': 'label: Inactivating thyroid-stimulating hormone receptor defect\ndefinition : Loss-of-function thyroid-stimulating hormone receptor (TSHR) defect.\nsynonyms :Inactivating TSHR defect\n'}


{'id': 'HP_0011792', 'url': 'http://purl.obolibrary.org/obo/HP_0011792', 'lbl': 'Neoplasm by histology', 'desc': 'label: Neoplasm by histology\ndefinition : Neoplasm categorized according to type of histological abnormality.\nsynonyms :\n'}


{'id': 'HP_0011793', 'url': 'http://purl.obolibrary.org/obo/HP_0011793', 'lbl': 'Neoplasm by anatomical site', 'desc': 'label: Neoplasm by anatomical site\ndefinition : Neoplasm categorized according to the anatomical site of origin of the neoplasm.\nsynonyms :\n'}


{'id': 'HP_0011794', 'url': 'http://purl.obolibrary.org/obo/HP_0011794', 'lbl': 'Embryonal renal neoplasm', 'desc': 'label: Embryonal renal neoplasm\ndefinition : The presence of an embryonal neoplasm of the kidney that primarily affects children.\nsynonyms :\n'}


{'id': 'HP_0011795', 'url': 'http://purl.obolibrary.org/obo/HP_0011795', 'lbl': 'Intralobar nephroblastomatosis', 'desc': 'label: Intralobar nephroblastomatosis\ndefinition : Presence of persistent islands of renal blastema in the postnatal kidney, anywhere within a renal lobe (a portion of a kidney consisting of a renal pyramid and the renal cortex above it).\nsynonyms :\n'}


{'id': 'HP_0011796', 'url': 'http://purl.obolibrary.org/obo/HP_0011796', 'lbl': 'Perilobar nephroblastomatosis', 'desc': 'label: Perilobar nephroblastomatosis\ndefinition : Abnormally persistent foci of embryonal immature blastema located in the superficial cortical region (perilobar).\nsynonyms :\n'}


{'id': 'HP_0011797', 'url': 'http://purl.obolibrary.org/obo/HP_0011797', 'lbl': 'Papillary renal cell carcinoma type 1', 'desc': 'label: Papillary renal cell carcinoma type 1\ndefinition : A type of papillary renal cell carcinoma that is characterized by small cuboidal cells covering thin papillae with a single line of uniform nuclei and small nucleoli.\nsynonyms :\n'}


{'id': 'HP_0011798', 'url': 'http://purl.obolibrary.org/obo/HP_0011798', 'lbl': 'Renal oncocytoma', 'desc': 'label: Renal oncocytoma\ndefinition : A renal tumor originating from an oncocyte, which is an epithelial cell characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm.\nsynonyms :\n'}


{'id': 'HP_0011799', 'url': 'http://purl.obolibrary.org/obo/HP_0011799', 'lbl': 'Abnormality of facial soft tissue', 'desc': 'label: Abnormality of facial soft tissue\ndefinition : \nsynonyms :Abnormality of facial soft tissue; Anomaly of facial soft tissue; Deformity of facial soft tissue; Malformation of facial soft tissue\n'}


{'id': 'HP_0011800', 'url': 'http://purl.obolibrary.org/obo/HP_0011800', 'lbl': 'Midface retrusion', 'desc': 'label: Midface retrusion\ndefinition : Posterior positions and/or vertical shortening of the infraorbital and perialar regions, or increased concavity of the face and/or reduced nasolabial angle.\nsynonyms :Small midface; Decreased size of midface; Flat midface; Hypoplasia of midface; Midface deficiency; Midface hypoplasia; Midface retrusion; Midface, flat; Retrusive midface; Underdevelopment of midface; Decreased projection of midface; Hypotrophic midface\n'}


{'id': 'HP_0011801', 'url': 'http://purl.obolibrary.org/obo/HP_0011801', 'lbl': 'Enlargement of parotid gland', 'desc': 'label: Enlargement of parotid gland\ndefinition : Increased size of the parotid gland.\nsynonyms :Hyperplasia of parotid gland; Increased size of parotid gland; Hypertrophy of parotid gland\n'}


{'id': 'HP_0011802', 'url': 'http://purl.obolibrary.org/obo/HP_0011802', 'lbl': 'Hamartoma of tongue', 'desc': 'label: Hamartoma of tongue\ndefinition : A benign (noncancerous) tumorlike malformation made up of an abnormal mixture of cells and tissues that originates in the tongue.\nsynonyms :Lingual hamartoma\n'}


{'id': 'HP_0011803', 'url': 'http://purl.obolibrary.org/obo/HP_0011803', 'lbl': 'Bifid nose', 'desc': 'label: Bifid nose\ndefinition : Visually assessable vertical indentation, cleft, or depression of the nasal bridge, ridge and tip.\nsynonyms :Bifid nasal bridge; Indentation or clefting of the nose; Cleft nasal bridge; Cleft nose; Indented bridge of nose\n'}


{'id': 'HP_0011804', 'url': 'http://purl.obolibrary.org/obo/HP_0011804', 'lbl': 'Abnormal muscle physiology', 'desc': 'label: Abnormal muscle physiology\ndefinition : A functional abnormality of a skeletal muscle.\nsynonyms :Abnormality of muscle physiology; Issue with muscle function\n'}


{'id': 'HP_0011805', 'url': 'http://purl.obolibrary.org/obo/HP_0011805', 'lbl': 'Abnormal skeletal muscle morphology', 'desc': 'label: Abnormal skeletal muscle morphology\ndefinition : A structural abnormality of a skeletal muscle.\nsynonyms :Abnormal muscle morphology; Abnormality of muscle morphology; Abnormally shaped muscle; Issue with muscle structure\n'}


{'id': 'HP_0011807', 'url': 'http://purl.obolibrary.org/obo/HP_0011807', 'lbl': 'Type 1 muscle fiber atrophy', 'desc': 'label: Type 1 muscle fiber atrophy\ndefinition : Atrophy (wasting) affecting primary type 1 muscle fibers. This feature in general can only be observed on muscle biopsy.\nsynonyms :Type 1 muscle fibre atrophy\n'}


{'id': 'HP_0011808', 'url': 'http://purl.obolibrary.org/obo/HP_0011808', 'lbl': 'Decreased patellar reflex', 'desc': 'label: Decreased patellar reflex\ndefinition : Decreased intensity of the patellar reflex (also known as the knee jerk reflex).\nsynonyms :Decreased knee jerk reflex; Decreased patellar reflexes\n'}


{'id': 'HP_0011809', 'url': 'http://purl.obolibrary.org/obo/HP_0011809', 'lbl': 'Paradoxical myotonia', 'desc': 'label: Paradoxical myotonia\ndefinition : A type of myotonia that worsens with repeated muscle contractions.\nsynonyms :\n'}


{'id': 'HP_0011810', 'url': 'http://purl.obolibrary.org/obo/HP_0011810', 'lbl': 'Impaired two-point discrimination', 'desc': 'label: Impaired two-point discrimination\ndefinition : A reduced ability to distinguish tactile sensations at points that are very close to one another. This can be tested by using special calipers whose points can be set from 2mm to several centimeters apart.\nsynonyms :\n'}


{'id': 'HP_0011811', 'url': 'http://purl.obolibrary.org/obo/HP_0011811', 'lbl': 'Impaired touch localization', 'desc': 'label: Impaired touch localization\ndefinition : A reduced ability to identify precisely the site of a touch. This test is usually carried out by asking a patient, whose eyes are closed or covered, to touch the same site with a fingertip.\nsynonyms :Impaired topognosis; Impaired touch localisation\n'}


{'id': 'HP_0011812', 'url': 'http://purl.obolibrary.org/obo/HP_0011812', 'lbl': 'Agraphesthesia', 'desc': "label: Agraphesthesia\ndefinition : Impaired ability to recognize letters or numbers drawn by an examiner's fingertip on the patient's skin (the patients eyes are closed or covered throughout this examination).\nsynonyms :\n"}


{'id': 'HP_0011813', 'url': 'http://purl.obolibrary.org/obo/HP_0011813', 'lbl': 'Increased cerebral lipofuscin', 'desc': 'label: Increased cerebral lipofuscin\ndefinition : Lipofuscin (age pigment) is a brown-yellow, electron-dense, autofluorescent material that accumulates progressively over time in lysosomes of postmitotic cells, such as neurons and cardiac myocytes. This term pertains if there is an increase in the accumulation of lipofuscin (also known as autofluorescent lipoprotein) more than expected for the age of the patient.\nsynonyms :\n'}


{'id': 'HP_0011814', 'url': 'http://purl.obolibrary.org/obo/HP_0011814', 'lbl': 'Increased urinary hypoxanthine', 'desc': 'label: Increased urinary hypoxanthine\ndefinition : An increased level of hypoxanthine in the urine.\nsynonyms :\n'}


{'id': 'HP_0011815', 'url': 'http://purl.obolibrary.org/obo/HP_0011815', 'lbl': 'Cephalocele', 'desc': 'label: Cephalocele\ndefinition : A congenital defect in the skull, whereby there is a protrusion of part of the cranial contents through a congenital defect in the cranium, usually covered with skin or mucous membrane. The term encephalocele refers to a subclass of these lesions in which brain tissue protrudes through the defect.\nsynonyms :\n'}


{'id': 'HP_0011816', 'url': 'http://purl.obolibrary.org/obo/HP_0011816', 'lbl': 'Parietal encephalocele', 'desc': 'label: Parietal encephalocele\ndefinition : An encephalocele located between bregma and lambda.\nsynonyms :\n'}


{'id': 'HP_0011817', 'url': 'http://purl.obolibrary.org/obo/HP_0011817', 'lbl': 'Basal encephalocele', 'desc': 'label: Basal encephalocele\ndefinition : Basal encephalocele is an encephalocele that occurs along the cribriform plate or through the sphenoid bone. The mass may appear in the nasal cavity, nasopharynx, epipharynx, sphenoid sinus, posterior orbit, or pterygopalatine fossa. The important distinction from other types is that no external tumor is visible except in those rare instances of herniations so large that they protrude through the mouth or nares.\nsynonyms :\n'}


{'id': 'HP_0011818', 'url': 'http://purl.obolibrary.org/obo/HP_0011818', 'lbl': 'Nasofrontal encephalocele', 'desc': 'label: Nasofrontal encephalocele\ndefinition : \nsynonyms :Naso-frontal encephalocele\n'}


{'id': 'HP_0011819', 'url': 'http://purl.obolibrary.org/obo/HP_0011819', 'lbl': 'Submucous cleft soft palate', 'desc': 'label: Submucous cleft soft palate\ndefinition : A cleft of the muscular (soft) portion of the palate that is covered by mucous membrane. Soft-palate submucous clefts are characterized by a midline deficiency or lack of muscle tissue.\nsynonyms :Partial thickness cleft soft palate; Submucous cleft velum\n'}


{'id': 'HP_0011820', 'url': 'http://purl.obolibrary.org/obo/HP_0011820', 'lbl': 'Membranous choanal atresia', 'desc': 'label: Membranous choanal atresia\ndefinition : Absence of the normal opening of the choana (the posterior nasal aperture) as a result of an obstructing choanal membrane that may be thin and strandlike or thick and pluglike.\nsynonyms :\n'}


{'id': 'HP_0011821', 'url': 'http://purl.obolibrary.org/obo/HP_0011821', 'lbl': 'Abnormal facial skeleton morphology', 'desc': 'label: Abnormal facial skeleton morphology\ndefinition : An abnormality of one or more of the set of bones that make up the facial skeleton.\nsynonyms :Abnormality of facial skeleton; Anomaly of facial skeleton; Abnormality of facial bones; Anomaly of facial bones; Deformity of facial skeleton; Deformity of the facial bones; Malformation of facial bones; Malformation of facial skeleton\n'}


{'id': 'HP_0011822', 'url': 'http://purl.obolibrary.org/obo/HP_0011822', 'lbl': 'Broad chin', 'desc': 'label: Broad chin\ndefinition : Increased width of the midpoint of the mandible (mental protuberance) and overlying soft tissue.\nsynonyms :Broad chin; Increased width of chin; Increased width of menton region; Wide chin\n'}


{'id': 'HP_0011823', 'url': 'http://purl.obolibrary.org/obo/HP_0011823', 'lbl': 'Chin with horizontal crease', 'desc': 'label: Chin with horizontal crease\ndefinition : Horizontal crease or fold situated below the vermilion border of the lower lip and above the fatty pad of the chin, with the face at rest.\nsynonyms :Chin with horizontal crease; Chin with horizontal furrow; Chin with horizontal groove; Chin with horizontal sulcus; Horizontal chin skin cleft; Horizontal menton crease\n'}


{'id': 'HP_0011824', 'url': 'http://purl.obolibrary.org/obo/HP_0011824', 'lbl': 'Chin with H-shaped crease', 'desc': 'label: Chin with H-shaped crease\ndefinition : H-shaped crease in the fat pad of the chin.\nsynonyms :Chin with H-shaped crease; Chin, H-Shaped Crease; Chin, H-shaped groove; H-shaped dimple of the chin\n'}


{'id': 'HP_0011825', 'url': 'http://purl.obolibrary.org/obo/HP_0011825', 'lbl': 'Tented philtrum', 'desc': 'label: Tented philtrum\ndefinition : Prominence of a triangular soft tissue area of the philtrum with the apex to the columella.\nsynonyms :Philtrum, Tented\n'}


{'id': 'HP_0011826', 'url': 'http://purl.obolibrary.org/obo/HP_0011826', 'lbl': 'Philtrum with midline raphe', 'desc': 'label: Philtrum with midline raphe\ndefinition : Narrow ridge in the midline of the philtral groove.\nsynonyms :Philtrum with central raphe; Philtrum with midline ridge; Philtrum, midline raphe\n'}


{'id': 'HP_0011827', 'url': 'http://purl.obolibrary.org/obo/HP_0011827', 'lbl': 'Malaligned philtral ridges', 'desc': 'label: Malaligned philtral ridges\ndefinition : Absence of the usual parallel position of philtral ridges.\nsynonyms :Asymmetric philtral columns; Asymmetric philtral ridges; Malaligned philtral columns; Philtral Ridges, Malaligned\n'}


{'id': 'HP_0011828', 'url': 'http://purl.obolibrary.org/obo/HP_0011828', 'lbl': 'Midline sinus of philtrum', 'desc': 'label: Midline sinus of philtrum\ndefinition : Pit in the midline of the philtral groove.\nsynonyms :Central sinus of philtrum; Philtrum, Midline Sinus\n'}


{'id': 'HP_0011829', 'url': 'http://purl.obolibrary.org/obo/HP_0011829', 'lbl': 'Narrow philtrum', 'desc': 'label: Narrow philtrum\ndefinition : Distance between the philtral ridges, measured just above the vermilion border, more than 2 standard deviations below the mean. Alternatively, an apparently decreased distance between the ridges of the philtrum.\nsynonyms :Decreased breadth of philtrum; Decreased horizontal dimension of philtrum; Decreased transverse dimension of philtrum; Decreased width of philtrum; Philtrum, Narrow; Thin philtrum\n'}


{'id': 'HP_0011830', 'url': 'http://purl.obolibrary.org/obo/HP_0011830', 'lbl': 'Abnormal oral mucosa morphology', 'desc': 'label: Abnormal oral mucosa morphology\ndefinition : Abnormality of the oral mucosa.\nsynonyms :Abnormality of lining of mouth; Abnormality of mucosa of mouth; Abnormality of oral mucosa; Abnormality of oral mucous membrane\n'}


{'id': 'HP_0011831', 'url': 'http://purl.obolibrary.org/obo/HP_0011831', 'lbl': 'Deviated nasal tip', 'desc': 'label: Deviated nasal tip\ndefinition : Nasal tip positioned to one side of the midline.\nsynonyms :Asymmetry of nasal tip; Asymmetry of tip of nose; Crooked nasal tip; Crooked tip of nose; Deviated nasal tip; Deviated tip of nose; Nasal tip, deviated; Distortion of the nasal tip\n'}


{'id': 'HP_0011832', 'url': 'http://purl.obolibrary.org/obo/HP_0011832', 'lbl': 'Narrow nasal tip', 'desc': 'label: Narrow nasal tip\ndefinition : Decrease in width of the nasal tip.\nsynonyms :Narrow nasal tip; Narrow tip of nose; Nasal tip, narrow; Nasal tip, pinched; Pinched nasal tip; Pinched tip of nose; Thin nasal tip; Thin tip of nose\n'}


{'id': 'HP_0011833', 'url': 'http://purl.obolibrary.org/obo/HP_0011833', 'lbl': 'Overhanging nasal tip', 'desc': 'label: Overhanging nasal tip\ndefinition : Positioning of the nasal tip inferior to the nasal base.\nsynonyms :Drooping nasal tip; Hooked tip of nose; Low hanging nasal tip; Nasal tip, overhanging; Overhanging nasal tip\n'}


{'id': 'HP_0011834', 'url': 'http://purl.obolibrary.org/obo/HP_0011834', 'lbl': 'Moyamoya phenomenon', 'desc': 'label: Moyamoya phenomenon\ndefinition : A noninflammatory, progressive occlusion of the intracranial carotid arteries owing to the formation of netlike collateral arteries arising from the circle of Willis.\nsynonyms :\n'}


{'id': 'HP_0011835', 'url': 'http://purl.obolibrary.org/obo/HP_0011835', 'lbl': 'Absent scaphoid', 'desc': 'label: Absent scaphoid\ndefinition : Congenital absence of the scaphoid..\nsynonyms :Missing scaphoid bone; Absent scaphoid bone\n'}


{'id': 'HP_0011836', 'url': 'http://purl.obolibrary.org/obo/HP_0011836', 'lbl': 'Delayed talus ossification', 'desc': 'label: Delayed talus ossification\ndefinition : Delayed maturation and calcification of the talus.\nsynonyms :\n'}


{'id': 'HP_0011837', 'url': 'http://purl.obolibrary.org/obo/HP_0011837', 'lbl': 'Partial IgA deficiency', 'desc': 'label: Partial IgA deficiency\ndefinition : Detectable but decreased IgA levels that are more than 2 standard deviations below normal age-adjusted means.\nsynonyms :\n'}


{'id': 'HP_0011838', 'url': 'http://purl.obolibrary.org/obo/HP_0011838', 'lbl': 'Sclerodactyly', 'desc': 'label: Sclerodactyly\ndefinition : Localized thickening and tightness of the skin of the fingers or toes.\nsynonyms :\n'}


{'id': 'HP_0011839', 'url': 'http://purl.obolibrary.org/obo/HP_0011839', 'lbl': 'Abnormal T cell count', 'desc': 'label: Abnormal T cell count\ndefinition : A deviation from the normal count of T cells.\nsynonyms :Abnormal number of T cells; Abnormality of T cell number\n'}


{'id': 'HP_0011840', 'url': 'http://purl.obolibrary.org/obo/HP_0011840', 'lbl': 'Abnormality of T cell physiology', 'desc': 'label: Abnormality of T cell physiology\ndefinition : A functional anomaly of T cells.\nsynonyms :\n'}


{'id': 'HP_0011841', 'url': 'http://purl.obolibrary.org/obo/HP_0011841', 'lbl': 'Ventricular flutter', 'desc': 'label: Ventricular flutter\ndefinition : A potentially lethal cardiac arrhythmia characterized by an extremely rapid, hemodynamically unstable ventricular tachycardia (150-300 beats/min) with a large oscillating sine-wave appearance.\nsynonyms :\n'}


{'id': 'HP_0011842', 'url': 'http://purl.obolibrary.org/obo/HP_0011842', 'lbl': 'Abnormal skeletal morphology', 'desc': 'label: Abnormal skeletal morphology\ndefinition : An abnormality of the form, structure, or size of the skeletal system.\nsynonyms :Abnormality of skeletal morphology; Abnormally shaped skeletal\n'}


{'id': 'HP_0011843', 'url': 'http://purl.obolibrary.org/obo/HP_0011843', 'lbl': 'Abnormal musculoskeletal physiology', 'desc': 'label: Abnormal musculoskeletal physiology\ndefinition : An abnormality of the function of the skeletal system.\nsynonyms :Abnormality of musculoskeletal physiology\n'}


{'id': 'HP_0011844', 'url': 'http://purl.obolibrary.org/obo/HP_0011844', 'lbl': 'Abnormal appendicular skeleton morphology', 'desc': 'label: Abnormal appendicular skeleton morphology\ndefinition : An abnormality of the appendicular skeletal system, consisting of the of the limbs, shoulder and pelvic girdles.\nsynonyms :\n'}


{'id': 'HP_0011845', 'url': 'http://purl.obolibrary.org/obo/HP_0011845', 'lbl': 'Short second metatarsal', 'desc': 'label: Short second metatarsal\ndefinition : Short (hypoplastic) second metatarsal bone.\nsynonyms :Short 2nd long bone of foot\n'}


{'id': 'HP_0011846', 'url': 'http://purl.obolibrary.org/obo/HP_0011846', 'lbl': 'Osteoblastoma', 'desc': 'label: Osteoblastoma\ndefinition : A benign, painful, tumor of bone characterized by the formation of osteoid tissue, primitive bone and calcified tissue.\nsynonyms :\n'}


{'id': 'HP_0011847', 'url': 'http://purl.obolibrary.org/obo/HP_0011847', 'lbl': 'Giant cell tumor of bone', 'desc': 'label: Giant cell tumor of bone\ndefinition : A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts.\nsynonyms :Giant cell tumour of bone\n'}


{'id': 'HP_0011848', 'url': 'http://purl.obolibrary.org/obo/HP_0011848', 'lbl': 'Abdominal colic', 'desc': 'label: Abdominal colic\ndefinition : A type of abdominal pain that comes and goes in waves, most often starting and ending suddenly and being of severe intensity.\nsynonyms :\n'}


{'id': 'HP_0011849', 'url': 'http://purl.obolibrary.org/obo/HP_0011849', 'lbl': 'Abnormal bone ossification', 'desc': 'label: Abnormal bone ossification\ndefinition : Any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.\nsynonyms :Abnormal bone maturation\n'}


{'id': 'HP_0011850', 'url': 'http://purl.obolibrary.org/obo/HP_0011850', 'lbl': 'Parotitis', 'desc': 'label: Parotitis\ndefinition : Inflammation of the parotid gland.\nsynonyms :\n'}


{'id': 'HP_0011851', 'url': 'http://purl.obolibrary.org/obo/HP_0011851', 'lbl': 'Hemopericardium', 'desc': 'label: Hemopericardium\ndefinition : Accumulation of blood within the pericardial sac.\nsynonyms :\n'}


{'id': 'HP_0011852', 'url': 'http://purl.obolibrary.org/obo/HP_0011852', 'lbl': 'Chylopericardium', 'desc': 'label: Chylopericardium\ndefinition : Accumulation of chyle (the whitish fluid taken up by the lacteals in the intestine, consisting of an emulsion of lymph and triglyceride fat thatpasses into the veins by the thoracic duct) in the pericardium. Chylopericardium is generally caused by obstruction of or trauma to the thoracic duct.\nsynonyms :\n'}


{'id': 'HP_0011853', 'url': 'http://purl.obolibrary.org/obo/HP_0011853', 'lbl': 'Serous pericardial effusion', 'desc': 'label: Serous pericardial effusion\ndefinition : Accumulation of serous fluid (pale yellow and transparent fluid) in the pericardial sac.\nsynonyms :\n'}


{'id': 'HP_0011854', 'url': 'http://purl.obolibrary.org/obo/HP_0011854', 'lbl': 'Hemoperitoneum', 'desc': 'label: Hemoperitoneum\ndefinition : Accumulation of blood in the peritoneal cavity owing to internal hemorrhage.\nsynonyms :Hematoperitoneum\n'}


{'id': 'HP_0011855', 'url': 'http://purl.obolibrary.org/obo/HP_0011855', 'lbl': 'Pharyngeal edema', 'desc': 'label: Pharyngeal edema\ndefinition : Abnormal accumulation of fluid leading to swelling of the pharynx.\nsynonyms :Pharyngeal oedema; Swollen throat; Throat swelling\n'}


{'id': 'HP_0011856', 'url': 'http://purl.obolibrary.org/obo/HP_0011856', 'lbl': 'Pica', 'desc': 'label: Pica\ndefinition : An appetite for and the persistent ingestion of non-food substances such as clay. In order to diagnose pica, this behavior must have persisted over a period of at least one month.\nsynonyms :\n'}


{'id': 'HP_0011857', 'url': 'http://purl.obolibrary.org/obo/HP_0011857', 'lbl': 'Plasmacytoma', 'desc': 'label: Plasmacytoma\ndefinition : A discrete mass of neoplastic monoclonal plasma cells either in the bone marrow or in an extramedullary location.\nsynonyms :\n'}


{'id': 'HP_0011858', 'url': 'http://purl.obolibrary.org/obo/HP_0011858', 'lbl': 'Reduced factor IX activity', 'desc': 'label: Reduced factor IX activity\ndefinition : Decreased activity of coagulation factor IX. Factor IX, which itself is activated by factor Xa or factor VIIa to form factor IXa, activates factor X into factor Xa.\nsynonyms :Low factor IX activity\n'}


{'id': 'HP_0011859', 'url': 'http://purl.obolibrary.org/obo/HP_0011859', 'lbl': 'Punctate keratitis', 'desc': 'label: Punctate keratitis\ndefinition : A type of keratitis characterized by inflammation in pinpoint areas of the corneal epithelium.\nsynonyms :\n'}


{'id': 'HP_0011860', 'url': 'http://purl.obolibrary.org/obo/HP_0011860', 'lbl': 'Metaphyseal dappling', 'desc': 'label: Metaphyseal dappling\ndefinition : The presence of spots or rounded patches of abnormally increased density of metaphyseal bone.\nsynonyms :Dappled metaphyseal sclerosis\n'}


{'id': 'HP_0011861', 'url': 'http://purl.obolibrary.org/obo/HP_0011861', 'lbl': 'Bilateral trilobed lung', 'desc': 'label: Bilateral trilobed lung\ndefinition : Both lungs have three lobes. Normally, the left lung has two lobes, whereas the right lung has three lobes.\nsynonyms :Bilateral trilobed lungs\n'}


{'id': 'HP_0011862', 'url': 'http://purl.obolibrary.org/obo/HP_0011862', 'lbl': 'Abnormal bone collagen fibril morphology', 'desc': 'label: Abnormal bone collagen fibril morphology\ndefinition : Any structural anomaly of the connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity.\nsynonyms :\n'}


{'id': 'HP_0011863', 'url': 'http://purl.obolibrary.org/obo/HP_0011863', 'lbl': 'Abnormal sternal ossification', 'desc': 'label: Abnormal sternal ossification\ndefinition : Any anomaly in the formation of the bony substance of the sternum.\nsynonyms :Abnormal maturation of breastbone; Sternal ossification center abnormalities; Sternal ossification centre abnormalities\n'}


{'id': 'HP_0011864', 'url': 'http://purl.obolibrary.org/obo/HP_0011864', 'lbl': 'Elevated plasma pyrophosphate', 'desc': 'label: Elevated plasma pyrophosphate\ndefinition : An abnormally increased diphosphate(4-) concentration in the blood. Diphosphate(4-), as ester with two phosphate groups, is also known as pyrophosphate.\nsynonyms :\n'}


{'id': 'HP_0011867', 'url': 'http://purl.obolibrary.org/obo/HP_0011867', 'lbl': 'Abnormal iliac wing morphology', 'desc': 'label: Abnormal iliac wing morphology\ndefinition : An anomaly of the ilium ala. This is the large expanded portion of the ilum which bounds the greater pelvis laterally.\nsynonyms :Abnormality of the wing of the ilium\n'}


{'id': 'HP_0011868', 'url': 'http://purl.obolibrary.org/obo/HP_0011868', 'lbl': 'Sciatica', 'desc': 'label: Sciatica\ndefinition : Pain in the lower back and hip radiating in the distribution of the sciatic nerve.\nsynonyms :\n'}


{'id': 'HP_0011869', 'url': 'http://purl.obolibrary.org/obo/HP_0011869', 'lbl': 'Abnormal platelet function', 'desc': 'label: Abnormal platelet function\ndefinition : Any anomaly in the function of thrombocytes.\nsynonyms :\n'}


{'id': 'HP_0011870', 'url': 'http://purl.obolibrary.org/obo/HP_0011870', 'lbl': 'Impaired arachidonic acid-induced platelet aggregation', 'desc': 'label: Impaired arachidonic acid-induced platelet aggregation\ndefinition : Abnormal response to arachidonic acid as manifested by reduced or lacking aggregation of platelets upon addition of arachidonic acid.\nsynonyms :\n'}


{'id': 'HP_0011871', 'url': 'http://purl.obolibrary.org/obo/HP_0011871', 'lbl': 'Impaired ristocetin-induced platelet aggregation', 'desc': 'label: Impaired ristocetin-induced platelet aggregation\ndefinition : Abnormal response to ristocetin as manifested by reduced or lacking aggregation of platelets upon addition of ristocetin.\nsynonyms :\n'}


{'id': 'HP_0011872', 'url': 'http://purl.obolibrary.org/obo/HP_0011872', 'lbl': 'Impaired thrombin-induced platelet aggregation', 'desc': 'label: Impaired thrombin-induced platelet aggregation\ndefinition : Abnormal response to thrombin or thrombin mimetics as manifested by reduced or lacking aggregation of platelets upon addition of thrombin (or thrombin mimetics).\nsynonyms :\n'}


{'id': 'HP_0011873', 'url': 'http://purl.obolibrary.org/obo/HP_0011873', 'lbl': 'Abnormal platelet count', 'desc': 'label: Abnormal platelet count\ndefinition : Abnormal number of platelets per volume of blood. In a healthy adult, a normal platelet count is between 150,000 and 450,000 per microliter of blood.\nsynonyms :\n'}


{'id': 'HP_0011874', 'url': 'http://purl.obolibrary.org/obo/HP_0011874', 'lbl': 'Heparin-induced thrombocytopenia', 'desc': 'label: Heparin-induced thrombocytopenia\ndefinition : Low platelet count following administration of unfractionated or (less commonly) low-molecular weight heparin.\nsynonyms :\n'}


{'id': 'HP_0011875', 'url': 'http://purl.obolibrary.org/obo/HP_0011875', 'lbl': 'Abnormal platelet morphology', 'desc': 'label: Abnormal platelet morphology\ndefinition : An anomaly in platelet form, ultrastructure, or intracellular organelles.\nsynonyms :Abnormal shape of platelets\n'}


{'id': 'HP_0011876', 'url': 'http://purl.obolibrary.org/obo/HP_0011876', 'lbl': 'Abnormal platelet volume', 'desc': 'label: Abnormal platelet volume\ndefinition : Anomalous size of platelets. Most normal sized platelets are 1.5 to 3 micrometers in diameter. Large platelets are 4 to 7 micrometers. Giant platelets are larger than 7 micrometers and usually 10 to 20 micrometers.\nsynonyms :\n'}


{'id': 'HP_0011877', 'url': 'http://purl.obolibrary.org/obo/HP_0011877', 'lbl': 'Increased mean platelet volume', 'desc': 'label: Increased mean platelet volume\ndefinition : Average platelet volume above the upper limit of the normal reference interval.\nsynonyms :Large platelets\n'}


{'id': 'HP_0011878', 'url': 'http://purl.obolibrary.org/obo/HP_0011878', 'lbl': 'Abnormal platelet membrane protein expression', 'desc': 'label: Abnormal platelet membrane protein expression\ndefinition : Presence of reduced amount of a membrane protein on the cell membrane of platelets. This feature is typically measured by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0011879', 'url': 'http://purl.obolibrary.org/obo/HP_0011879', 'lbl': 'Decreased platelet glycoprotein Ib-IX-V', 'desc': 'label: Decreased platelet glycoprotein Ib-IX-V\ndefinition : Decreased cell membrane concentration of the glycoprotein complex Ib-IX-V.\nsynonyms :\n'}


{'id': 'HP_0011880', 'url': 'http://purl.obolibrary.org/obo/HP_0011880', 'lbl': 'Acute disseminated intravascular coagulation', 'desc': 'label: Acute disseminated intravascular coagulation\ndefinition : An acute form of disseminated intravascular coagulation. Acute DIC can occur following sudden exposure of blood to procoagulants, with the compensatory hemostatic mechanisms becoming overwhelmed.\nsynonyms :\n'}


{'id': 'HP_0011881', 'url': 'http://purl.obolibrary.org/obo/HP_0011881', 'lbl': 'Decreased platelet glycoprotein VI', 'desc': 'label: Decreased platelet glycoprotein VI\ndefinition : Decreased cell membrane concentration of glycoprotein VI.\nsynonyms :\n'}


{'id': 'HP_0011882', 'url': 'http://purl.obolibrary.org/obo/HP_0011882', 'lbl': 'Decreased platelet P2Y12 receptor', 'desc': 'label: Decreased platelet P2Y12 receptor\ndefinition : Decreased cell membrane concentration of P2Y12 receptor.\nsynonyms :\n'}


{'id': 'HP_0011883', 'url': 'http://purl.obolibrary.org/obo/HP_0011883', 'lbl': 'Abnormal platelet granules', 'desc': 'label: Abnormal platelet granules\ndefinition : An anomaly of alpha or dense granules or platelet lysosomes.\nsynonyms :\n'}


{'id': 'HP_0011884', 'url': 'http://purl.obolibrary.org/obo/HP_0011884', 'lbl': 'Abnormal umbilical stump bleeding', 'desc': 'label: Abnormal umbilical stump bleeding\ndefinition : Abnormal bleeding of the umbilical stump following separation of the cord at approximately 7-10 days after birth.\nsynonyms :\n'}


{'id': 'HP_0011885', 'url': 'http://purl.obolibrary.org/obo/HP_0011885', 'lbl': 'Hemorrhage of the eye', 'desc': 'label: Hemorrhage of the eye\ndefinition : Bleeding from vessels of the various tissues of the eye.\nsynonyms :Bleeding from the eye; Haemorrhage of the eye\n'}


{'id': 'HP_0011886', 'url': 'http://purl.obolibrary.org/obo/HP_0011886', 'lbl': 'Hyphema', 'desc': 'label: Hyphema\ndefinition : Bleeding in the anterior chamber of the eye.\nsynonyms :\n'}


{'id': 'HP_0011887', 'url': 'http://purl.obolibrary.org/obo/HP_0011887', 'lbl': 'Choroid hemorrhage', 'desc': 'label: Choroid hemorrhage\ndefinition : Hemorrhage from the vessels of the choroid.\nsynonyms :Choroid haemorrhage; Choroidal haemorrhage; Choroidal hemorrhage\n'}


{'id': 'HP_0011888', 'url': 'http://purl.obolibrary.org/obo/HP_0011888', 'lbl': 'Bleeding requiring red cell transfusion', 'desc': 'label: Bleeding requiring red cell transfusion\ndefinition : Bleeding sufficiently severe as to require red cell transfusion (WHO Grade 3 or 4).\nsynonyms :Bleeding requiring red cell transfusion\n'}


{'id': 'HP_0011889', 'url': 'http://purl.obolibrary.org/obo/HP_0011889', 'lbl': 'Bleeding with minor or no trauma', 'desc': 'label: Bleeding with minor or no trauma\ndefinition : Significant bleeding or hemorrhage without significant precipitating factor.\nsynonyms :Bleeding with minor or no trauma; Easy bleeding\n'}


{'id': 'HP_0011890', 'url': 'http://purl.obolibrary.org/obo/HP_0011890', 'lbl': 'Prolonged bleeding following procedure', 'desc': 'label: Prolonged bleeding following procedure\ndefinition : Prolonged or protracted bleeding following an invasive procedure or intervention.\nsynonyms :Prolonged bleeding following procedure\n'}


{'id': 'HP_0011891', 'url': 'http://purl.obolibrary.org/obo/HP_0011891', 'lbl': 'Post-partum hemorrhage', 'desc': 'label: Post-partum hemorrhage\ndefinition : Significant maternal haemorrhage/blood loss following deilvery of a child.\nsynonyms :Bleeding post-delivery; Post-partum haemorrhage\n'}


{'id': 'HP_0011892', 'url': 'http://purl.obolibrary.org/obo/HP_0011892', 'lbl': 'Low levels of vitamin K', 'desc': 'label: Low levels of vitamin K\ndefinition : A reduced concentration of vitamin K.\nsynonyms :\n'}


{'id': 'HP_0011893', 'url': 'http://purl.obolibrary.org/obo/HP_0011893', 'lbl': 'Abnormal leukocyte count', 'desc': 'label: Abnormal leukocyte count\ndefinition : Number of leukocytes per volume of blood beyond normal limits.\nsynonyms :Abnormal white blood cell count\n'}


{'id': 'HP_0011894', 'url': 'http://purl.obolibrary.org/obo/HP_0011894', 'lbl': 'Impaired thromboxane A2 agonist-induced platelet aggregation', 'desc': 'label: Impaired thromboxane A2 agonist-induced platelet aggregation\ndefinition : Abnormal response to thromboxane as manifested by reduced or lacking aggregation of platelets upon addition of thromboxane A2 receptor agonists.\nsynonyms :\n'}


{'id': 'HP_0011895', 'url': 'http://purl.obolibrary.org/obo/HP_0011895', 'lbl': 'Anemia due to reduced life span of red cells', 'desc': 'label: Anemia due to reduced life span of red cells\ndefinition : A type of anemia related to a reduction in the average life span of red blood cells in the peripheral circulation, which is normally around 120 days.\nsynonyms :Anaemia due to reduced life span of red cells\n'}


{'id': 'HP_0011896', 'url': 'http://purl.obolibrary.org/obo/HP_0011896', 'lbl': 'Subconjunctival hemorrhage', 'desc': 'label: Subconjunctival hemorrhage\ndefinition : Bleeding beneath the mucous membrane that lines the inner surface of the eyelid.\nsynonyms :Subconjunctival haemorrhage\n'}


{'id': 'HP_0011897', 'url': 'http://purl.obolibrary.org/obo/HP_0011897', 'lbl': 'Neutrophilia', 'desc': 'label: Neutrophilia\ndefinition : Increased number of neutrophils circulating in blood.\nsynonyms :Increased blood neutrophil counts\n'}


{'id': 'HP_0011898', 'url': 'http://purl.obolibrary.org/obo/HP_0011898', 'lbl': 'Abnormality of circulating fibrinogen', 'desc': 'label: Abnormality of circulating fibrinogen\ndefinition : An abnormality of the level of activity of circulating fibrinogen.\nsynonyms :\n'}


{'id': 'HP_0011899', 'url': 'http://purl.obolibrary.org/obo/HP_0011899', 'lbl': 'Hyperfibrinogenemia', 'desc': 'label: Hyperfibrinogenemia\ndefinition : Increased concentration of fibrinogen in the blood.\nsynonyms :\n'}


{'id': 'HP_0011900', 'url': 'http://purl.obolibrary.org/obo/HP_0011900', 'lbl': 'Hypofibrinogenemia', 'desc': 'label: Hypofibrinogenemia\ndefinition : Decreased concentration of fibrinogen in the blood.\nsynonyms :Low fibrinogen activity; Low fibrinogen level\n'}


{'id': 'HP_0011901', 'url': 'http://purl.obolibrary.org/obo/HP_0011901', 'lbl': 'Dysfibrinogenemia', 'desc': 'label: Dysfibrinogenemia\ndefinition : Qualitatively abnormal fibrinogen.\nsynonyms :Dysfibrinogenaemia\n'}


{'id': 'HP_0011902', 'url': 'http://purl.obolibrary.org/obo/HP_0011902', 'lbl': 'Abnormal hemoglobin', 'desc': 'label: Abnormal hemoglobin\ndefinition : Anomaly in the level or the function of hemoglobin, the oxygen-carrying protein of erythrocytes.\nsynonyms :Abnormal Hb; Abnormal haemoglobin\n'}


{'id': 'HP_0011903', 'url': 'http://purl.obolibrary.org/obo/HP_0011903', 'lbl': 'HbH hemoglobin', 'desc': 'label: HbH hemoglobin\ndefinition : Hemoglobin H (HbH) contains four beta-globin chains. It is normally not present at all in blood, but may make up about 1-40 percent of all hemoglobin in HbH disease, a subform of alpha thalassemia.\nsynonyms :Haemoglobin H; HbH haemoglobin; Hemoglobin H\n'}


{'id': 'HP_0011904', 'url': 'http://purl.obolibrary.org/obo/HP_0011904', 'lbl': 'Persistence of hemoglobin F', 'desc': 'label: Persistence of hemoglobin F\ndefinition : Hemoglobin F (HbF) contains two globin alpha chains and two globin gamma chains. It is the main form of hemoglobin in the fetus during the last seven months of intrauterine development and in the half year of postnatal life. In adults it normally makes up less than one percent of all hemoglobin. This term refers to an increase in HbF above this limit. In beta thalassemia major, it may represent over 90 percent of all hemoglobin, and in beta thalassemia minor it may make up between 0.5 to 4 percent.\nsynonyms :Increased haemoglobin F; Increased hemoglobin F; Persistence of HbF; Persistence of haemoglobin F\n'}


{'id': 'HP_0011905', 'url': 'http://purl.obolibrary.org/obo/HP_0011905', 'lbl': 'Reduced hemoglobin A', 'desc': 'label: Reduced hemoglobin A\ndefinition : Hemoglobin A (HbA) contains two globin alpha chains and two globin beta chains. HbA is normally the main adult hemoglobin, representing about 96-98 percent of all hemoglobin. This term represents a decreased in the proportion of HbA below this limit, and can be seen in various forms of thalassemia.\nsynonyms :Reduced HbA; Reduced haemoglobin A\n'}


{'id': 'HP_0011906', 'url': 'http://purl.obolibrary.org/obo/HP_0011906', 'lbl': 'Reduced beta/alpha synthesis ratio', 'desc': 'label: Reduced beta/alpha synthesis ratio\ndefinition : A reduction in the ratio of production of beta globin to that of alpha globin. This is the major abnormality in the various forms of beta thalassemia.\nsynonyms :\n'}


{'id': 'HP_0011907', 'url': 'http://purl.obolibrary.org/obo/HP_0011907', 'lbl': 'Reduced alpha/beta synthesis ratio', 'desc': 'label: Reduced alpha/beta synthesis ratio\ndefinition : A reduction in the ratio of production of alpha globin to that of beta globin. This is the major abnormality in the various forms of alpha thalassemia.\nsynonyms :\n'}


{'id': 'HP_0011908', 'url': 'http://purl.obolibrary.org/obo/HP_0011908', 'lbl': 'Unilateral radial aplasia', 'desc': 'label: Unilateral radial aplasia\ndefinition : Missing radius bone on one side only associated with congenital failure of development.\nsynonyms :\n'}


{'id': 'HP_0011909', 'url': 'http://purl.obolibrary.org/obo/HP_0011909', 'lbl': 'Flattened metacarpal heads', 'desc': 'label: Flattened metacarpal heads\ndefinition : Abnormally flat shape of the heads of the metacarpal bones.\nsynonyms :Flattened head of long bone of hand\n'}


{'id': 'HP_0011910', 'url': 'http://purl.obolibrary.org/obo/HP_0011910', 'lbl': 'Shortening of all phalanges of fingers', 'desc': 'label: Shortening of all phalanges of fingers\ndefinition : Abnormal reduction in length affecting all phalanges.\nsynonyms :Shortening of all finger bones\n'}


{'id': 'HP_0011911', 'url': 'http://purl.obolibrary.org/obo/HP_0011911', 'lbl': 'Abnormal metacarpophalangeal joint morphology', 'desc': 'label: Abnormal metacarpophalangeal joint morphology\ndefinition : An anomaly of a metacarpophalangeal joint.\nsynonyms :Abnormality of metacarpophalangeal joint; Abnormality of the knuckle\n'}


{'id': 'HP_0011912', 'url': 'http://purl.obolibrary.org/obo/HP_0011912', 'lbl': 'Abnormality of the glenoid fossa', 'desc': 'label: Abnormality of the glenoid fossa\ndefinition : An anomaly of the glenoid fossa, also known as the glenoid cavity, which is the articular surface of the scapula that articulates with the head of the humerus.\nsynonyms :\n'}


{'id': 'HP_0011913', 'url': 'http://purl.obolibrary.org/obo/HP_0011913', 'lbl': 'Lumbar hypertrichosis', 'desc': 'label: Lumbar hypertrichosis\ndefinition : Excessive, increased hair growth located in the lumbar region.\nsynonyms :\n'}


{'id': 'HP_0011914', 'url': 'http://purl.obolibrary.org/obo/HP_0011914', 'lbl': 'Thoracic hypertrichosis', 'desc': 'label: Thoracic hypertrichosis\ndefinition : Excessive, increased hair growth located in the thoracic region.\nsynonyms :\n'}


{'id': 'HP_0011915', 'url': 'http://purl.obolibrary.org/obo/HP_0011915', 'lbl': 'Cardiovascular calcification', 'desc': 'label: Cardiovascular calcification\ndefinition : Abnormal calcification in the cardiovascular system.\nsynonyms :\n'}


{'id': 'HP_0011916', 'url': 'http://purl.obolibrary.org/obo/HP_0011916', 'lbl': 'Toe extensor amyotrophy', 'desc': 'label: Toe extensor amyotrophy\ndefinition : Atrophy of the extensor digitorum longus muscles, which mediate extension of the toes.\nsynonyms :\n'}


{'id': 'HP_0011917', 'url': 'http://purl.obolibrary.org/obo/HP_0011917', 'lbl': 'Short 5th toe', 'desc': 'label: Short 5th toe\ndefinition : Underdevelopment (hypoplasia) of the fifth toe.\nsynonyms :Short fifth toe; Short little toe; Short pinkie toe; Short pinky toe\n'}


{'id': 'HP_0011918', 'url': 'http://purl.obolibrary.org/obo/HP_0011918', 'lbl': 'Clinodactyly of the 4th toe', 'desc': 'label: Clinodactyly of the 4th toe\ndefinition : Bending or curvature of a fourth toe in the tibial direction (i.e., towards the big toe).\nsynonyms :Curvature of 4th toe; 4th toe clinodactyly\n'}


{'id': 'HP_0011919', 'url': 'http://purl.obolibrary.org/obo/HP_0011919', 'lbl': 'Pleural empyema', 'desc': 'label: Pleural empyema\ndefinition : Accumulation of pus in the pleural cavity.\nsynonyms :Pyothorax\n'}


{'id': 'HP_0011920', 'url': 'http://purl.obolibrary.org/obo/HP_0011920', 'lbl': 'Transudative pleural effusion', 'desc': "label: Transudative pleural effusion\ndefinition : A type of pleural effusion with a transudate (extravascular fluid with low protein content and a low specific gravity). Pleural effusions can be classified as transudates or exudates based on Light's criteria, which classify an effusion as exudate if one or more of the following are present: (1) the ratio of pleural fluid protein to serum protein is greater than 0.5, (2) the ratio of pleural fluid lactate dehydrogenase (LDH) to serum LDH is greater than 0.6, or (3) the pleural fluid LDH level is greater than two thirds of the upper limit of normal for serum LDH.\nsynonyms :\n"}


{'id': 'HP_0011921', 'url': 'http://purl.obolibrary.org/obo/HP_0011921', 'lbl': 'Exudative pleural effusion', 'desc': "label: Exudative pleural effusion\ndefinition : A type of pleural effusion with a exudate (extravascular fluid that has exuded out of a tissue or its capillaries due to injury or inflammation). Pleural effusions can be classified as transudates or exudates based on Light's criteria, which classify an effusion as exudate if one or more of the following are present: (1) the ratio of pleural fluid protein to serum protein is greater than 0.5, (2) the ratio of pleural fluid lactate dehydrogenase (LDH) to serum LDH is greater than 0.6, or (3) the pleural fluid LDH level is greater than two thirds of the upper limit of normal for serum LDH.\nsynonyms :\n"}


{'id': 'HP_0011922', 'url': 'http://purl.obolibrary.org/obo/HP_0011922', 'lbl': 'Abnormal activity of mitochondrial respiratory chain', 'desc': 'label: Abnormal activity of mitochondrial respiratory chain\ndefinition : An increased or decreased activity of the mitochondrial respiratory chain.\nsynonyms :\n'}


{'id': 'HP_0011923', 'url': 'http://purl.obolibrary.org/obo/HP_0011923', 'lbl': 'Decreased activity of mitochondrial complex I', 'desc': 'label: Decreased activity of mitochondrial complex I\ndefinition : A reduction in the activity of the mitochondrial respiratory chain complex I, which is part of the electron transport chain in mitochondria.\nsynonyms :Respiratory complex I deficiency\n'}


{'id': 'HP_0011924', 'url': 'http://purl.obolibrary.org/obo/HP_0011924', 'lbl': 'Decreased activity of mitochondrial complex III', 'desc': 'label: Decreased activity of mitochondrial complex III\ndefinition : A reduction in the activity of the mitochondrial respiratory chain complex III, which is part of the electron transport chain in mitochondria.\nsynonyms :Respiratory complex III deficiency\n'}


{'id': 'HP_0011925', 'url': 'http://purl.obolibrary.org/obo/HP_0011925', 'lbl': 'Decreased activity of mitochondrial ATP synthase complex', 'desc': 'label: Decreased activity of mitochondrial ATP synthase complex\ndefinition : A reduction in the activity of the mitochondrial proton-transporting ATP synthase complex, which makes ATP via oxidative phosphorylation, and is sometimes described as Complex V of the electron transport chain.\nsynonyms :Decreased activity of mitochondrial complex V; Mitochondrial complex V deficiency; Respiratory complex deficiency, ATPase deficiency\n'}


{'id': 'HP_0011926', 'url': 'http://purl.obolibrary.org/obo/HP_0011926', 'lbl': 'Proximal placement of hallux', 'desc': 'label: Proximal placement of hallux\ndefinition : Proximal mislocalization of the big toe from its normal position.\nsynonyms :Proximal placement of big toe; Proximally placed halluces\n'}


{'id': 'HP_0011927', 'url': 'http://purl.obolibrary.org/obo/HP_0011927', 'lbl': 'Short digit', 'desc': 'label: Short digit\ndefinition : One or more digit that appears disproportionately short compared to the hand/foot, whereby either the entire digit or a specific phalanx is shortened.\nsynonyms :Short digit; Very short digits\n'}


{'id': 'HP_0011928', 'url': 'http://purl.obolibrary.org/obo/HP_0011928', 'lbl': 'Short proximal phalanx of toe', 'desc': 'label: Short proximal phalanx of toe\ndefinition : Developmental hypoplasia (shortening) of proximal phalanx of toe.\nsynonyms :Short innermost toe bone\n'}


{'id': 'HP_0011929', 'url': 'http://purl.obolibrary.org/obo/HP_0011929', 'lbl': 'Hypersegmentation of proximal phalanx of third finger', 'desc': 'label: Hypersegmentation of proximal phalanx of third finger\ndefinition : Presence of an additional phalanx-like bone, producing an extra, wedge-shaped bone at the base of the proximal phalanx of the third finger.\nsynonyms :\n'}


{'id': 'HP_0011930', 'url': 'http://purl.obolibrary.org/obo/HP_0011930', 'lbl': 'Hyperextensible skin of chest', 'desc': 'label: Hyperextensible skin of chest\ndefinition : \nsynonyms :Hyperelastic chest skin; Stretchable chest skin\n'}


{'id': 'HP_0011931', 'url': 'http://purl.obolibrary.org/obo/HP_0011931', 'lbl': 'Abnormal cerebellar peduncle morphology', 'desc': 'label: Abnormal cerebellar peduncle morphology\ndefinition : An anomaly of the cerebellar peduncles. The superior, middle, and inferior cerebellar peduncles emerge from the cerebellum. The superior cerebellar penduncles connect the cerebellum to the midbrain, the middle cerebellar peduncles connect the cerebellum to the pons, and the inferior cerebellar peduncle connects the medulla spinalis and medulla oblongata with the cerebellum.\nsynonyms :Abnormality of the cerebellar peduncle\n'}


{'id': 'HP_0011932', 'url': 'http://purl.obolibrary.org/obo/HP_0011932', 'lbl': 'Abnormal superior cerebellar peduncle morphology', 'desc': 'label: Abnormal superior cerebellar peduncle morphology\ndefinition : An anomaly of the superior cerebellar peduncle.\nsynonyms :Abnormality of the superior cerebellar peduncle\n'}


{'id': 'HP_0011933', 'url': 'http://purl.obolibrary.org/obo/HP_0011933', 'lbl': 'Elongated superior cerebellar peduncle', 'desc': 'label: Elongated superior cerebellar peduncle\ndefinition : Increased length of the superior cerebellar peduncle.\nsynonyms :Long cerebellar peduncle; Long cerebellar peduncles; Elongated superior cerebellar peduncles\n'}


{'id': 'HP_0011934', 'url': 'http://purl.obolibrary.org/obo/HP_0011934', 'lbl': 'Dilatation of mesenteric artery', 'desc': 'label: Dilatation of mesenteric artery\ndefinition : Abnormal outpouching or sac-like dilatation in the wall of the inferior mesenteric artery or superior mesenteric artery .\nsynonyms :Mesenteric artery aneurysm\n'}


{'id': 'HP_0011935', 'url': 'http://purl.obolibrary.org/obo/HP_0011935', 'lbl': 'Decreased urinary urate', 'desc': 'label: Decreased urinary urate\ndefinition : Decreased concentration of urate in the urine.\nsynonyms :\n'}


{'id': 'HP_0011936', 'url': 'http://purl.obolibrary.org/obo/HP_0011936', 'lbl': 'Decreased plasma total carnitine', 'desc': 'label: Decreased plasma total carnitine\ndefinition : A decreased concentration of total carnitine in the blood.\nsynonyms :Decreased plasma total carnitine\n'}


{'id': 'HP_0011937', 'url': 'http://purl.obolibrary.org/obo/HP_0011937', 'lbl': 'Hypoplastic fifth toenail', 'desc': 'label: Hypoplastic fifth toenail\ndefinition : Underdeveloped nails of the fifth toes.\nsynonyms :Small fifth toenail; Underdeveloped fifth toenail\n'}


{'id': 'HP_0011939', 'url': 'http://purl.obolibrary.org/obo/HP_0011939', 'lbl': '3-4 finger cutaneous syndactyly', 'desc': 'label: 3-4 finger cutaneous syndactyly\ndefinition : A soft tissue continuity in the A/P axis between fingers 3 and 4.\nsynonyms :\n'}


{'id': 'HP_0011940', 'url': 'http://purl.obolibrary.org/obo/HP_0011940', 'lbl': 'Anterior wedging of T12', 'desc': 'label: Anterior wedging of T12\ndefinition : An abnormality of the shape of the thoracic vertebra T12 such that it is wedge-shaped (narrow towards the front).\nsynonyms :Anterior wedging of the 12th thoracic vertebra; Wedge-shaped 12th thoracic vertebra\n'}


{'id': 'HP_0011941', 'url': 'http://purl.obolibrary.org/obo/HP_0011941', 'lbl': 'Anterior wedging of L2', 'desc': 'label: Anterior wedging of L2\ndefinition : An abnormality of the shape of the lumbar vertebra L2 such that it is wedge-shaped (narrow towards the front).\nsynonyms :\n'}


{'id': 'HP_0011942', 'url': 'http://purl.obolibrary.org/obo/HP_0011942', 'lbl': 'Increased urinary sulfite', 'desc': 'label: Increased urinary sulfite\ndefinition : Increased concentration of SO3(2-), i.e., sulfite, in the urine.\nsynonyms :\n'}


{'id': 'HP_0011943', 'url': 'http://purl.obolibrary.org/obo/HP_0011943', 'lbl': 'Increased urinary thiosulfate', 'desc': 'label: Increased urinary thiosulfate\ndefinition : Increased concentration of thiosulfate(2-) in the urine.\nsynonyms :\n'}


{'id': 'HP_0011944', 'url': 'http://purl.obolibrary.org/obo/HP_0011944', 'lbl': 'Small vessel vasculitis', 'desc': 'label: Small vessel vasculitis\ndefinition : A type of vasculitis (inflammation of blood vessel walls) that affects blood vessels that are smaller than arteries, i.e., arterioles, venules, and capilllaries.\nsynonyms :\n'}


{'id': 'HP_0011945', 'url': 'http://purl.obolibrary.org/obo/HP_0011945', 'lbl': 'Bronchiolitis obliterans organizing pneumonia', 'desc': 'label: Bronchiolitis obliterans organizing pneumonia\ndefinition : Bronchiolitis obliterans organizing pneumonia (BOOP) is and interstitial lung abnormalitiy characterized histopathologically by plugs of granulation tissue lying within small airways, alveolar ducts, and alveoli and by chronic inflammatory cell infiltration in alveolar walls. Patients with BOOP generally present with subacute illness, including shortness of breath, fever, malaise, and weight loss.\nsynonyms :BOOP; Bronchiolitis obliterans organising pneumonia; Cryptogenic organising pneumonia; Cryptogenic organizing pneumonia\n'}


{'id': 'HP_0011946', 'url': 'http://purl.obolibrary.org/obo/HP_0011946', 'lbl': 'Bronchiolitis obliterans', 'desc': 'label: Bronchiolitis obliterans\ndefinition : Inflammation and fibrosis of the bronchioles leading to partial or complete obstruction of these airways.\nsynonyms :Constrictive bronchiolitis; Obliterative bronchiolitis\n'}


{'id': 'HP_0011947', 'url': 'http://purl.obolibrary.org/obo/HP_0011947', 'lbl': 'Respiratory tract infection', 'desc': 'label: Respiratory tract infection\ndefinition : An infection of the upper or lower respiratory tract.\nsynonyms :Respiratory infection; Respiratory tract infection; Respiratory infections\n'}


{'id': 'HP_0011948', 'url': 'http://purl.obolibrary.org/obo/HP_0011948', 'lbl': 'Recurrent acute respiratory tract infection', 'desc': 'label: Recurrent acute respiratory tract infection\ndefinition : A history of repeated acute infections of the upper or lower respiratory tract.\nsynonyms :Acute respiratory tract infection\n'}


{'id': 'HP_0011949', 'url': 'http://purl.obolibrary.org/obo/HP_0011949', 'lbl': 'Acute infectious pneumonia', 'desc': 'label: Acute infectious pneumonia\ndefinition : Acute inflammation of the lung due to an infection.\nsynonyms :\n'}


{'id': 'HP_0011950', 'url': 'http://purl.obolibrary.org/obo/HP_0011950', 'lbl': 'Bronchiolitis', 'desc': 'label: Bronchiolitis\ndefinition : Inflammation of the bronchioles.\nsynonyms :\n'}


{'id': 'HP_0011951', 'url': 'http://purl.obolibrary.org/obo/HP_0011951', 'lbl': 'Aspiration pneumonia', 'desc': 'label: Aspiration pneumonia\ndefinition : Pneumonia due to the aspiration (breathing in) of food, liquid, or gastric contents into the upper respiratory tract.\nsynonyms :\n'}


{'id': 'HP_0011952', 'url': 'http://purl.obolibrary.org/obo/HP_0011952', 'lbl': 'Acute aspiration pneumonia', 'desc': 'label: Acute aspiration pneumonia\ndefinition : An acute episode of pneumonia due to the aspiration (breathing in) of food, liquid, or gastric contents into the upper respiratory tract.\nsynonyms :\n'}


{'id': 'HP_0011953', 'url': 'http://purl.obolibrary.org/obo/HP_0011953', 'lbl': 'Pulmonary lymphoma', 'desc': 'label: Pulmonary lymphoma\ndefinition : Lung parenchymal involvement with lymphoma.\nsynonyms :\n'}


{'id': 'HP_0011954', 'url': 'http://purl.obolibrary.org/obo/HP_0011954', 'lbl': 'Nodular regenerative hyperplasia of liver', 'desc': 'label: Nodular regenerative hyperplasia of liver\ndefinition : Diffuse benign transformation of the hepatic parenchyma into small regenerative nodules with minimal or no fibrosis.\nsynonyms :Nodular transformation of liver; Noncirrhotic nodulation; Partial nodular transformation of liver\n'}


{'id': 'HP_0011955', 'url': 'http://purl.obolibrary.org/obo/HP_0011955', 'lbl': 'Hepatic granulomatosis', 'desc': 'label: Hepatic granulomatosis\ndefinition : The presence of multiple granulomas in the liver as based on pathological examination. Granulomas are small 0.5 to 2 mm collections of modified macrophages called epithelioid cells usually surrounded by lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0011956', 'url': 'http://purl.obolibrary.org/obo/HP_0011956', 'lbl': 'Intestinal lymphoid nodular hyperplasia', 'desc': 'label: Intestinal lymphoid nodular hyperplasia\ndefinition : A lymphoproliferative abnormality of the intestine characterized by numerous visible mucosal nodules measuring up to, and rarely exceeding, 0.5 cm in diameter Histologically, hyperplastic lymphoid follicles with large germinal centres are seen in the lamina propria and superficial submucosa. There is enlargement of the mucosal B cell follicles caused by hyperplasia of the follicle centres; surrounded by a normal appearing mantle zone. Disease may involve the stomach, the entire small intestine, and the large intestine.\nsynonyms :\n'}


{'id': 'HP_0011957', 'url': 'http://purl.obolibrary.org/obo/HP_0011957', 'lbl': 'Abnormal pectoral muscle morphology', 'desc': 'label: Abnormal pectoral muscle morphology\ndefinition : An abnormality of the pectoral muscle, comprising the pectoralis major, a thick, fan-shaped muscle of the anterior chest and the pectoralis minor, a thin, triangular muscle situated underneath the pectoralis major.\nsynonyms :Abnormal pec muscles\n'}


{'id': 'HP_0011958', 'url': 'http://purl.obolibrary.org/obo/HP_0011958', 'lbl': 'Retinal perforation', 'desc': 'label: Retinal perforation\ndefinition : A small hole through the whole thickness of the retina.\nsynonyms :Retinal tear; Torn retina\n'}


{'id': 'HP_0011959', 'url': 'http://purl.obolibrary.org/obo/HP_0011959', 'lbl': 'Unilateral hypoplasia of pectoralis major muscle', 'desc': 'label: Unilateral hypoplasia of pectoralis major muscle\ndefinition : Hypoplasia (underdevelopment) of the pectoralis minor on only one side of the chest.\nsynonyms :Small pec muscle on one side; Underdeveloped pec muscle on one side\n'}


{'id': 'HP_0011960', 'url': 'http://purl.obolibrary.org/obo/HP_0011960', 'lbl': 'Substantia nigra gliosis', 'desc': 'label: Substantia nigra gliosis\ndefinition : Focal proliferation of glial cells in the substantia nigra.\nsynonyms :\n'}


{'id': 'HP_0011961', 'url': 'http://purl.obolibrary.org/obo/HP_0011961', 'lbl': 'Non-obstructive azoospermia', 'desc': 'label: Non-obstructive azoospermia\ndefinition : Absence of any measurable level of sperm in his semen, resulting from a defect in the production of spermatozoa in the testes. This can be differentiated from obstructive azoospermia on the basis of testicular biopsy.\nsynonyms :Testicular azoospermia\n'}


{'id': 'HP_0011962', 'url': 'http://purl.obolibrary.org/obo/HP_0011962', 'lbl': 'Obstructive azoospermia', 'desc': 'label: Obstructive azoospermia\ndefinition : Absence of any measurable level of sperm in his semen, resulting from post-testicular obstruction or retrograde ejaculation. This can be differentiated from obstructive azoospermia on the basis of testicular biopsy.\nsynonyms :\n'}


{'id': 'HP_0011963', 'url': 'http://purl.obolibrary.org/obo/HP_0011963', 'lbl': 'Pretesticular azoospermia', 'desc': 'label: Pretesticular azoospermia\ndefinition : Absence of any measurable level of sperm in his semen, due to a hypothalamic or pituitary abnormality diagnosed with hypo-gonadotropic-hypogonadism. The diagnosis is made on the basis of low LH and FSH levels and low or normal testosterone levels.\nsynonyms :\n'}


{'id': 'HP_0011964', 'url': 'http://purl.obolibrary.org/obo/HP_0011964', 'lbl': 'Intermittent painful muscle spasms', 'desc': 'label: Intermittent painful muscle spasms\ndefinition : History of repeated intermittent involuntary muscle contractions that were painful.\nsynonyms :\n'}


{'id': 'HP_0011965', 'url': 'http://purl.obolibrary.org/obo/HP_0011965', 'lbl': 'Abnormal circulating citrulline concentration', 'desc': 'label: Abnormal circulating citrulline concentration\ndefinition : Any deviation from the normal concentration of citrulline in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0011966', 'url': 'http://purl.obolibrary.org/obo/HP_0011966', 'lbl': 'Elevated plasma citrulline', 'desc': 'label: Elevated plasma citrulline\ndefinition : An increased concentration of citrulline in the blood.\nsynonyms :\n'}


{'id': 'HP_0011967', 'url': 'http://purl.obolibrary.org/obo/HP_0011967', 'lbl': 'Decreased circulating copper concentration', 'desc': 'label: Decreased circulating copper concentration\ndefinition : A reduced concentration of copper in the blood.\nsynonyms :Copper deficiency; Hypocupremia; Reduced serum copper\n'}


{'id': 'HP_0011968', 'url': 'http://purl.obolibrary.org/obo/HP_0011968', 'lbl': 'Feeding difficulties', 'desc': 'label: Feeding difficulties\ndefinition : Impaired ability to eat related to problems gathering food and getting ready to suck, chew, or swallow it.\nsynonyms :Feeding difficulties; Feeding problems; Poor feeding\n'}


{'id': 'HP_0011969', 'url': 'http://purl.obolibrary.org/obo/HP_0011969', 'lbl': 'Elevated circulating luteinizing hormone level', 'desc': 'label: Elevated circulating luteinizing hormone level\ndefinition : An elevated concentration of luteinizing hormone in the blood.\nsynonyms :Elevated LH level; Elevated luteinizing hormone; Increased circulating luteinizing hormone level\n'}


{'id': 'HP_0011970', 'url': 'http://purl.obolibrary.org/obo/HP_0011970', 'lbl': 'Cerebral amyloid angiopathy', 'desc': 'label: Cerebral amyloid angiopathy\ndefinition : Amyloid deposition in the walls of leptomeningeal and cortical arteries, arterioles, and less often capillaries and veins of the central nervous system.\nsynonyms :\n'}


{'id': 'HP_0011971', 'url': 'http://purl.obolibrary.org/obo/HP_0011971', 'lbl': 'Dermatographic urticaria', 'desc': 'label: Dermatographic urticaria\ndefinition : An exaggerated whealing tendency when the skin is stroked, that is, formation of red, itchy bumps and lines on the skin as a result of pressure on the skin (for instance, stroking the skin with a pen or tongue depressor).\nsynonyms :Dermatographism; Dermographism; Skin writing\n'}


{'id': 'HP_0011972', 'url': 'http://purl.obolibrary.org/obo/HP_0011972', 'lbl': 'Hypoglycorrhachia', 'desc': 'label: Hypoglycorrhachia\ndefinition : Abnormally low glucose concentration in the cerebrospinal fluid.\nsynonyms :Decreased CSF glucose; Low glucose levels in cerebral spinal fluid\n'}


{'id': 'HP_0011973', 'url': 'http://purl.obolibrary.org/obo/HP_0011973', 'lbl': 'Paroxysmal lethargy', 'desc': 'label: Paroxysmal lethargy\ndefinition : Repeated episodes of sudden-onset and transient lethargy.\nsynonyms :\n'}


{'id': 'HP_0011974', 'url': 'http://purl.obolibrary.org/obo/HP_0011974', 'lbl': 'Myelofibrosis', 'desc': 'label: Myelofibrosis\ndefinition : Replacement of bone marrow by fibrous tissue.\nsynonyms :\n'}


{'id': 'HP_0011975', 'url': 'http://purl.obolibrary.org/obo/HP_0011975', 'lbl': 'Aminoglycoside-induced hearing loss', 'desc': 'label: Aminoglycoside-induced hearing loss\ndefinition : Partial or complete loss of hearing following ingestion of aminoglycoside antibiotics.\nsynonyms :\n'}


{'id': 'HP_0011976', 'url': 'http://purl.obolibrary.org/obo/HP_0011976', 'lbl': 'Elevated urinary catecholamines', 'desc': 'label: Elevated urinary catecholamines\ndefinition : An increased concentration of catecholamine in the urine.\nsynonyms :Elevated urinary catecholamines\n'}


{'id': 'HP_0011977', 'url': 'http://purl.obolibrary.org/obo/HP_0011977', 'lbl': 'Elevated urinary homovanillic acid', 'desc': 'label: Elevated urinary homovanillic acid\ndefinition : An increased concentration of homovanillic acid in the urine.\nsynonyms :Increased urinary homovanillic acid\n'}


{'id': 'HP_0011978', 'url': 'http://purl.obolibrary.org/obo/HP_0011978', 'lbl': 'Elevated urinary vanillylmandelic acid', 'desc': 'label: Elevated urinary vanillylmandelic acid\ndefinition : An increased concentration of vanillylmandelic acid in the urine.\nsynonyms :Increased urinary vanillylmandelic acid\n'}


{'id': 'HP_0011979', 'url': 'http://purl.obolibrary.org/obo/HP_0011979', 'lbl': 'Elevated urinary dopamine', 'desc': 'label: Elevated urinary dopamine\ndefinition : An increased concentration of dopamine in the urine.\nsynonyms :Elevated urinary dopamine\n'}


{'id': 'HP_0011980', 'url': 'http://purl.obolibrary.org/obo/HP_0011980', 'lbl': 'Cholesterol gallstones', 'desc': 'label: Cholesterol gallstones\ndefinition : Gallstones composed primarily of cholesterol, usually about 2-3 cm in length with an oval form and a yellow or green/brown color.\nsynonyms :\n'}


{'id': 'HP_0011981', 'url': 'http://purl.obolibrary.org/obo/HP_0011981', 'lbl': 'Pigment gallstones', 'desc': 'label: Pigment gallstones\ndefinition : Gallstones composed primarily of bilirubin and calcium salts (calcium bilirubinate) with a low cholesterol concentration.\nsynonyms :\n'}


{'id': 'HP_0011982', 'url': 'http://purl.obolibrary.org/obo/HP_0011982', 'lbl': 'Black pigment gallstones', 'desc': 'label: Black pigment gallstones\ndefinition : A type of pigment gallstone that is hard and black, containing calcium carbonate and calcium phosphates.\nsynonyms :\n'}


{'id': 'HP_0011983', 'url': 'http://purl.obolibrary.org/obo/HP_0011983', 'lbl': 'Brown pigment gallstones', 'desc': 'label: Brown pigment gallstones\ndefinition : A type of pigment gallstone that is brown, containing calcium fatty acids. These stones are softer than black pigment gallstones.\nsynonyms :\n'}


{'id': 'HP_0011984', 'url': 'http://purl.obolibrary.org/obo/HP_0011984', 'lbl': 'Atretic gallbladder', 'desc': 'label: Atretic gallbladder\ndefinition : Failure of formation of the lumen of the gallbladder, often associated with gallbladder hypoplasia.\nsynonyms :Gallbladder atresia\n'}


{'id': 'HP_0011985', 'url': 'http://purl.obolibrary.org/obo/HP_0011985', 'lbl': 'Acholic stools', 'desc': 'label: Acholic stools\ndefinition : Clay colored stools lacking bile pigment.\nsynonyms :Acholia; Clay colored stools; Clay coloured stools; Discolored, acholic stools\n'}


{'id': 'HP_0011986', 'url': 'http://purl.obolibrary.org/obo/HP_0011986', 'lbl': 'Ectopic ossification', 'desc': 'label: Ectopic ossification\ndefinition : Formation of abnormal, extraskeletal bony tissue, i.e., the presence of bone in soft tissue where bone normally does not exist.\nsynonyms :Ectopic bone formation; Heterotopic ossification\n'}


{'id': 'HP_0011987', 'url': 'http://purl.obolibrary.org/obo/HP_0011987', 'lbl': 'Ectopic ossification in muscle tissue', 'desc': 'label: Ectopic ossification in muscle tissue\ndefinition : Formation of abnormal bony tissue within muscle tissue.\nsynonyms :Calcification of muscle tissue\n'}


{'id': 'HP_0011988', 'url': 'http://purl.obolibrary.org/obo/HP_0011988', 'lbl': 'Ectopic ossification in tendon tissue', 'desc': 'label: Ectopic ossification in tendon tissue\ndefinition : Formation of abnormal bony tissue within tendon tissue.\nsynonyms :\n'}


{'id': 'HP_0011989', 'url': 'http://purl.obolibrary.org/obo/HP_0011989', 'lbl': 'Ectopic ossification in ligament tissue', 'desc': 'label: Ectopic ossification in ligament tissue\ndefinition : Formation of abnormal bony tissue within ligament tissue.\nsynonyms :\n'}


{'id': 'HP_0011990', 'url': 'http://purl.obolibrary.org/obo/HP_0011990', 'lbl': 'Abnormality of neutrophil physiology', 'desc': 'label: Abnormality of neutrophil physiology\ndefinition : A functional abnormality of neutrophils.\nsynonyms :\n'}


{'id': 'HP_0011991', 'url': 'http://purl.obolibrary.org/obo/HP_0011991', 'lbl': 'Abnormal neutrophil count', 'desc': 'label: Abnormal neutrophil count\ndefinition : A deviation from the normal range of neutrophil cell counts in the circulation.\nsynonyms :Abnormal neutrophil cell number\n'}


{'id': 'HP_0011992', 'url': 'http://purl.obolibrary.org/obo/HP_0011992', 'lbl': 'Abnormality of neutrophil morphology', 'desc': 'label: Abnormality of neutrophil morphology\ndefinition : An abnormal form or size of neutrophils.\nsynonyms :\n'}


{'id': 'HP_0011993', 'url': 'http://purl.obolibrary.org/obo/HP_0011993', 'lbl': 'Impaired neutrophil bactericidal activity', 'desc': 'label: Impaired neutrophil bactericidal activity\ndefinition : A reduction in the ability of neutrophils to kill bacteria.\nsynonyms :\n'}


{'id': 'HP_0011994', 'url': 'http://purl.obolibrary.org/obo/HP_0011994', 'lbl': 'Abnormal atrial septum morphology', 'desc': 'label: Abnormal atrial septum morphology\ndefinition : An abnormality of the interatrial septum.\nsynonyms :Abnormal interatrial septum morphology; Abnormality of the atrial septum\n'}


{'id': 'HP_0011995', 'url': 'http://purl.obolibrary.org/obo/HP_0011995', 'lbl': 'Atrial septal dilatation', 'desc': 'label: Atrial septal dilatation\ndefinition : A bulging of the interatrial septum towards one side. In adults, atrial septal aneurysm can be defined as a protrusion of the aneurysm of >10 mm beyond the plane of the atrial septum as measured by transesophageal echocardiography.\nsynonyms :Atrial septal aneurysm\n'}


{'id': 'HP_0011996', 'url': 'http://purl.obolibrary.org/obo/HP_0011996', 'lbl': 'Elevated coagulation factor V activity', 'desc': 'label: Elevated coagulation factor V activity\ndefinition : Increased activity of coagulation factor V, Factor V, which is activated to factor Va by means of minute amounts of thrombin (and inactivated by larger amounts of thrombin). Activated factor V (fVa) is a cofactor in the formation of the prothrombinase complex.\nsynonyms :Elevated factor V activity; Plasma factor V elevated\n'}


{'id': 'HP_0011997', 'url': 'http://purl.obolibrary.org/obo/HP_0011997', 'lbl': 'Postprandial hyperlactemia', 'desc': 'label: Postprandial hyperlactemia\ndefinition : Abnormally increased level of blood lactate following a meal.\nsynonyms :\n'}


{'id': 'HP_0011998', 'url': 'http://purl.obolibrary.org/obo/HP_0011998', 'lbl': 'Postprandial hyperglycemia', 'desc': 'label: Postprandial hyperglycemia\ndefinition : An increased concentration of glucose in the blood following a meal.\nsynonyms :\n'}


{'id': 'HP_0011999', 'url': 'http://purl.obolibrary.org/obo/HP_0011999', 'lbl': 'Paranoia', 'desc': 'label: Paranoia\ndefinition : A persecutory delusion of supposed hostility of others.\nsynonyms :Paranoia\n'}


{'id': 'HP_0012000', 'url': 'http://purl.obolibrary.org/obo/HP_0012000', 'lbl': 'EEG with generalized spikes', 'desc': 'label: EEG with generalized spikes\ndefinition : EEG with generalized sharp transient waves of a duration less than 80 msec.\nsynonyms :EEG with generalised spikes\n'}


{'id': 'HP_0012001', 'url': 'http://purl.obolibrary.org/obo/HP_0012001', 'lbl': 'EEG with generalized polyspikes', 'desc': 'label: EEG with generalized polyspikes\ndefinition : EEG with repetitive generalized sharp transient waves of a duration less than 80 msec.\nsynonyms :EEG with generalised polyspikes\n'}


{'id': 'HP_0012002', 'url': 'http://purl.obolibrary.org/obo/HP_0012002', 'lbl': 'Experiential epileptic aura', 'desc': 'label: Experiential epileptic aura\ndefinition : Affective, mnemonic or composite perceptual auras with subjective qualities similar to those experienced in life but are recognized by the subject as occurring outside of actual context.\nsynonyms :Experiential aura; Experiential auras\n'}


{'id': 'HP_0012003', 'url': 'http://purl.obolibrary.org/obo/HP_0012003', 'lbl': 'Affective epileptic aura', 'desc': 'label: Affective epileptic aura\ndefinition : Affective auras with subjective qualities similar to those experienced in life but are recognized by the subject as occurring outside of actual context.\nsynonyms :Affective aura; Affective auras; Emotional aura\n'}


{'id': 'HP_0012004', 'url': 'http://purl.obolibrary.org/obo/HP_0012004', 'lbl': 'Focal cognitive seizure with deja vu/jamais vu', 'desc': 'label: Focal cognitive seizure with deja vu/jamais vu\ndefinition : A focal cognitive seizure characterized by memory phenomena such as feelings of familiarity (deja vu) and unfamiliarity (jamais vu) as the initial semiological manifestation.\nsynonyms :Mnemonic aura; Mnemonic auras\n'}


{'id': 'HP_0012005', 'url': 'http://purl.obolibrary.org/obo/HP_0012005', 'lbl': 'Deja vu aura', 'desc': 'label: Deja vu aura\ndefinition : A subjective feeling that an experience which is occurring for the first time has been experienced before.\nsynonyms :Deja vu\n'}


{'id': 'HP_0012006', 'url': 'http://purl.obolibrary.org/obo/HP_0012006', 'lbl': 'Jamais vu aura', 'desc': 'label: Jamais vu aura\ndefinition : A subjective feeling that an experience which has occurred before is being experienced for the first time.\nsynonyms :Jamais vu\n'}


{'id': 'HP_0012007', 'url': 'http://purl.obolibrary.org/obo/HP_0012007', 'lbl': 'Focal cognitive seizure with hallucination', 'desc': 'label: Focal cognitive seizure with hallucination\ndefinition : A focal cognitive seizure characterized by hallucination as the initial semiological manifestation.\nsynonyms :Hallucinatory aura; Hallucinatory auras\n'}


{'id': 'HP_0012008', 'url': 'http://purl.obolibrary.org/obo/HP_0012008', 'lbl': 'Focal cognitive seizure with illusion', 'desc': 'label: Focal cognitive seizure with illusion\ndefinition : A focal cognitive seizure characterized by an alteration of actual perception involving visual, auditory, somatosensory, olfactory, and/or gustatory phenomena as the initial semiological manifestation.\nsynonyms :Illusory aura; Illusory auras\n'}


{'id': 'HP_0012009', 'url': 'http://purl.obolibrary.org/obo/HP_0012009', 'lbl': 'EEG with central focal spike waves', 'desc': 'label: EEG with central focal spike waves\ndefinition : EEG with focal sharp transient waves in the central region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave.\nsynonyms :\n'}


{'id': 'HP_0012010', 'url': 'http://purl.obolibrary.org/obo/HP_0012010', 'lbl': 'EEG with frontal focal spike waves', 'desc': 'label: EEG with frontal focal spike waves\ndefinition : EEG with focal sharp transient waves in the frontal region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave.\nsynonyms :\n'}


{'id': 'HP_0012011', 'url': 'http://purl.obolibrary.org/obo/HP_0012011', 'lbl': 'EEG with occipital focal spike waves', 'desc': 'label: EEG with occipital focal spike waves\ndefinition : EEG with focal sharp transient waves in the occipital region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave.\nsynonyms :\n'}


{'id': 'HP_0012012', 'url': 'http://purl.obolibrary.org/obo/HP_0012012', 'lbl': 'EEG with parietal focal spike waves', 'desc': 'label: EEG with parietal focal spike waves\ndefinition : EEG with focal sharp transient waves in the parietal region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave.\nsynonyms :\n'}


{'id': 'HP_0012013', 'url': 'http://purl.obolibrary.org/obo/HP_0012013', 'lbl': 'EEG with temporal focal spike waves', 'desc': 'label: EEG with temporal focal spike waves\ndefinition : EEG with focal sharp transient waves in the temporal region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave.\nsynonyms :\n'}


{'id': 'HP_0012014', 'url': 'http://purl.obolibrary.org/obo/HP_0012014', 'lbl': 'EEG with central focal spikes', 'desc': 'label: EEG with central focal spikes\ndefinition : EEG with focal sharp transient waves of a duration less than 80 msec in the central region.\nsynonyms :\n'}


{'id': 'HP_0012015', 'url': 'http://purl.obolibrary.org/obo/HP_0012015', 'lbl': 'EEG with frontal focal spikes', 'desc': 'label: EEG with frontal focal spikes\ndefinition : EEG with focal sharp transient waves of a duration less than 80 msec in the frontal region.\nsynonyms :\n'}


{'id': 'HP_0012016', 'url': 'http://purl.obolibrary.org/obo/HP_0012016', 'lbl': 'EEG with occipital focal spikes', 'desc': 'label: EEG with occipital focal spikes\ndefinition : EEG with focal sharp transient waves of a duration less than 80 msec in the occipital region.\nsynonyms :\n'}


{'id': 'HP_0012017', 'url': 'http://purl.obolibrary.org/obo/HP_0012017', 'lbl': 'EEG with parietal focal spikes', 'desc': 'label: EEG with parietal focal spikes\ndefinition : EEG with focal sharp transient waves of a duration less than 80 msec in the parietal region.\nsynonyms :\n'}


{'id': 'HP_0012018', 'url': 'http://purl.obolibrary.org/obo/HP_0012018', 'lbl': 'EEG with temporal focal spikes', 'desc': 'label: EEG with temporal focal spikes\ndefinition : EEG with focal sharp transient waves of a duration less than 80 msec in the temporal region.\nsynonyms :\n'}


{'id': 'HP_0012019', 'url': 'http://purl.obolibrary.org/obo/HP_0012019', 'lbl': 'Lens luxation', 'desc': 'label: Lens luxation\ndefinition : Complete dislocation of the lens of the eye.\nsynonyms :Dislocated lens; Dislocated lenses\n'}


{'id': 'HP_0012020', 'url': 'http://purl.obolibrary.org/obo/HP_0012020', 'lbl': 'Right aortic arch', 'desc': 'label: Right aortic arch\ndefinition : Aorta descends on right instead of on the left.\nsynonyms :Right-sided aortic arch\n'}


{'id': 'HP_0012021', 'url': 'http://purl.obolibrary.org/obo/HP_0012021', 'lbl': 'Persistent patent ductus venosus', 'desc': 'label: Persistent patent ductus venosus\ndefinition : Persistence of blood flow through the ductus venosus for longer than the normal time after birth.\nsynonyms :\n'}


{'id': 'HP_0012022', 'url': 'http://purl.obolibrary.org/obo/HP_0012022', 'lbl': 'Congenital portosystemic venous shunt', 'desc': 'label: Congenital portosystemic venous shunt\ndefinition : A congenital defect of the vasculature such that there is a shunt (by-pass) of blood directly from the portal vein to the vena cava (i.e., the blood from the portal vein is not filtered through the liver).\nsynonyms :\n'}


{'id': 'HP_0012023', 'url': 'http://purl.obolibrary.org/obo/HP_0012023', 'lbl': 'Galactosuria', 'desc': 'label: Galactosuria\ndefinition : Elevated concentration of galactose in the urine.\nsynonyms :Increased urinary galactose level\n'}


{'id': 'HP_0012024', 'url': 'http://purl.obolibrary.org/obo/HP_0012024', 'lbl': 'Hypergalactosemia', 'desc': 'label: Hypergalactosemia\ndefinition : Elevated concentration of galactose in the blood.\nsynonyms :Galactosemia\n'}


{'id': 'HP_0012025', 'url': 'http://purl.obolibrary.org/obo/HP_0012025', 'lbl': 'Abnormal circulating ornithine concentration', 'desc': 'label: Abnormal circulating ornithine concentration\ndefinition : Deviation from the normal concentration of ornithine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0012026', 'url': 'http://purl.obolibrary.org/obo/HP_0012026', 'lbl': 'Hyperornithinemia', 'desc': 'label: Hyperornithinemia\ndefinition : Increased concentration of ornithine in the blood.\nsynonyms :High blood ornithine levels\n'}


{'id': 'HP_0012027', 'url': 'http://purl.obolibrary.org/obo/HP_0012027', 'lbl': 'Laryngeal edema', 'desc': 'label: Laryngeal edema\ndefinition : An abnormal accumulation of fluid and swelling in the tissues of the larynx.\nsynonyms :Laryngeal oedema\n'}


{'id': 'HP_0012028', 'url': 'http://purl.obolibrary.org/obo/HP_0012028', 'lbl': 'Hepatocellular adenoma', 'desc': 'label: Hepatocellular adenoma\ndefinition : A benign tumor of the liver of presumably epithelial origin.\nsynonyms :Hepatic adenoma; Liver cell adenoma\n'}


{'id': 'HP_0012029', 'url': 'http://purl.obolibrary.org/obo/HP_0012029', 'lbl': 'Abnormal urine hormone level', 'desc': 'label: Abnormal urine hormone level\ndefinition : An abnormal concentration of a hormone in the urine.\nsynonyms :Abnormality of urine hormone level\n'}


{'id': 'HP_0012030', 'url': 'http://purl.obolibrary.org/obo/HP_0012030', 'lbl': 'Increased urinary cortisol level', 'desc': 'label: Increased urinary cortisol level\ndefinition : Abnormally increased concentration of cortisol in the urine.\nsynonyms :High urine cortisol level\n'}


{'id': 'HP_0012031', 'url': 'http://purl.obolibrary.org/obo/HP_0012031', 'lbl': 'Lipomatous tumor', 'desc': 'label: Lipomatous tumor\ndefinition : \nsynonyms :Lipomatous tumour\n'}


{'id': 'HP_0012032', 'url': 'http://purl.obolibrary.org/obo/HP_0012032', 'lbl': 'Lipoma', 'desc': 'label: Lipoma\ndefinition : Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous.\nsynonyms :Fatty lump; Noncancerous fatty lump\n'}


{'id': 'HP_0012033', 'url': 'http://purl.obolibrary.org/obo/HP_0012033', 'lbl': 'Sacral lipoma', 'desc': 'label: Sacral lipoma\ndefinition : Presence of a lipoma in the region of the sacrum.\nsynonyms :\n'}


{'id': 'HP_0012034', 'url': 'http://purl.obolibrary.org/obo/HP_0012034', 'lbl': 'Liposarcoma', 'desc': 'label: Liposarcoma\ndefinition : Malignant neoplasms which probably originate in primitive mesenchymal stem cell populations differentiating down a lipomatous pathway.\nsynonyms :\n'}


{'id': 'HP_0012035', 'url': 'http://purl.obolibrary.org/obo/HP_0012035', 'lbl': 'Steatocystoma multiplex', 'desc': 'label: Steatocystoma multiplex\ndefinition : Multiple, localized or widespread, asymptomatic or inflammatory dermal cysts involving the pilosebaceous units. Lesions can appear anywhere on the body, but steatocystoma multiplex is more commonly involved with those areas of the skin with a high density of developed pilosebaceous units (e.g., the axilla, groin, neck, and proximal extremities).\nsynonyms :\n'}