{'id': 'HP_0030710', 'url': 'http://purl.obolibrary.org/obo/HP_0030710', 'lbl': 'Lipomeningocele', 'desc': 'label: Lipomeningocele\ndefinition : A form of closed neural tube defect in which the spinal tissue lies within the spinal cord having a junction between the spinal cord and the lipoma. Intact skin covers the defect. Neurologic findings first appear during the second year of life.\nsynonyms :\n'}


{'id': 'HP_0030711', 'url': 'http://purl.obolibrary.org/obo/HP_0030711', 'lbl': 'Hydrocolpos', 'desc': 'label: Hydrocolpos\ndefinition : Distention of the vagina caused by accumulation of fluid due to congenital vaginal obstruction.\nsynonyms :\n'}


{'id': 'HP_0030712', 'url': 'http://purl.obolibrary.org/obo/HP_0030712', 'lbl': 'Uterine synechiae', 'desc': 'label: Uterine synechiae\ndefinition : Adhesions or scar tissue that form inside the cavity of the uterus.\nsynonyms :Asherman syndrome\n'}


{'id': 'HP_0030713', 'url': 'http://purl.obolibrary.org/obo/HP_0030713', 'lbl': 'Vein of Galen aneurysmal malformation', 'desc': 'label: Vein of Galen aneurysmal malformation\ndefinition : Vein of Galen aneurysmal malformation is a choroidal type of arteriovenous malformation that develops between 6 and 11 weeks of gestation. It results from 1 or more arteriovenous fistulas shunting blood toward the prosencephalic vein of Markowski, the embryonic precursor of the vein of Galen. This abnormal shunt leads to progressive dilation of the vein and prevents its involution and subsequent development into the vein of Galen.\nsynonyms :Median prosencephalic arteriovenous fistula; Vein of Galen aneurysm; Vein of Galen malformation\n'}


{'id': 'HP_0030714', 'url': 'http://purl.obolibrary.org/obo/HP_0030714', 'lbl': 'Subchorionic thrombohematoma', 'desc': "label: Subchorionic thrombohematoma\ndefinition : A large maternal clot that separates the chorionic plate from the villous chorion.\nsynonyms :Breus' mole\n"}


{'id': 'HP_0030715', 'url': 'http://purl.obolibrary.org/obo/HP_0030715', 'lbl': 'Bronchial atresia', 'desc': 'label: Bronchial atresia\ndefinition : A developmental anomaly characterised by focal obliteration of the proximal segment of a bronchus. The bronchial pattern is entirely normal distal to the site of stenosis.\nsynonyms :Congenital bronchial atresia\n'}


{'id': 'HP_0030716', 'url': 'http://purl.obolibrary.org/obo/HP_0030716', 'lbl': 'Acrania', 'desc': 'label: Acrania\ndefinition : Partial or complete absence of the flat bones of the cranial vault. The condition is frequently, though not always, associated with anencephaly.\nsynonyms :\n'}


{'id': 'HP_0030717', 'url': 'http://purl.obolibrary.org/obo/HP_0030717', 'lbl': 'Meconium peritonitis', 'desc': 'label: Meconium peritonitis\ndefinition : Peritonitis caused by intrauterine intestinal rupture and spillage of fetal meconium into the fetal peritoneal cavity. Intra-peritoneal meconium usually calcifies, sometimes within 24 hours. Ultrasound findings may include intraabdominal calcifications.\nsynonyms :\n'}


{'id': 'HP_0030718', 'url': 'http://purl.obolibrary.org/obo/HP_0030718', 'lbl': 'Right atrial enlargement', 'desc': 'label: Right atrial enlargement\ndefinition : Increase in size of the right atrium.\nsynonyms :Dilated right atrium; Enlarged heart right atrium; Right atrial dilatation\n'}


{'id': 'HP_0030719', 'url': 'http://purl.obolibrary.org/obo/HP_0030719', 'lbl': 'Unguarded tricuspid valve', 'desc': 'label: Unguarded tricuspid valve\ndefinition : A form of agenesis of the tricuspid valve in which (although the normal orifice between the right atrium and right ventricle exists) there is no tricuspid valvular tissue.\nsynonyms :Rudimentary tricuspid valve leaflets; Unguarded tricuspid valve orifice\n'}


{'id': 'HP_0030720', 'url': 'http://purl.obolibrary.org/obo/HP_0030720', 'lbl': 'Subchorionic septal cyst', 'desc': 'label: Subchorionic septal cyst\ndefinition : Cyst on the surface of the placenta consisting of amnion and chorion.\nsynonyms :\n'}


{'id': 'HP_0030721', 'url': 'http://purl.obolibrary.org/obo/HP_0030721', 'lbl': 'Tetraphocomelia', 'desc': 'label: Tetraphocomelia\ndefinition : Phocomelia involving all four extremities.\nsynonyms :\n'}


{'id': 'HP_0030722', 'url': 'http://purl.obolibrary.org/obo/HP_0030722', 'lbl': 'Ectopic liver', 'desc': 'label: Ectopic liver\ndefinition : Ectopic liver is a rare developmental anomaly in which liver tissue is situated outside the liver. Thus, ectopic liver refers to autonomous islands of normal liver parenchyma located outside the liver. The term ectopic liver is also used, to include liver appendices attached to the native liver by a thin stalk although being fully separated from the latter.\nsynonyms :\n'}


{'id': 'HP_0030723', 'url': 'http://purl.obolibrary.org/obo/HP_0030723', 'lbl': 'Congenital megalourethra', 'desc': 'label: Congenital megalourethra\ndefinition : Dilation and elongation of the penile urethra associated with absence or hypoplasia of the corpora spongiosa and cavernosa.\nsynonyms :\n'}


{'id': 'HP_0030724', 'url': 'http://purl.obolibrary.org/obo/HP_0030724', 'lbl': 'Central nervous system cyst', 'desc': 'label: Central nervous system cyst\ndefinition : A fluid-filled sac (cyst) located within the central nervous system.\nsynonyms :CNS cyst; Cyst of the central nervous system\n'}


{'id': 'HP_0030725', 'url': 'http://purl.obolibrary.org/obo/HP_0030725', 'lbl': 'Neurenteric cyst', 'desc': 'label: Neurenteric cyst\ndefinition : The neurenteric cyst is a rare lesion composed of heterotopic endodermal tissue. During the third week of human embryogenesis, the neurenteric canal unites the yolk sac and the amniotic cavity as it traverses the primitive notochordal plate. Persistence of the normally transient neurenteric canal prevents appropriate separation of endoderm and notochord. This results in a variable degree of communication between neural and enteric epithelium.\nsynonyms :\n'}


{'id': 'HP_0030726', 'url': 'http://purl.obolibrary.org/obo/HP_0030726', 'lbl': 'Spinal neurenteric cyst', 'desc': 'label: Spinal neurenteric cyst\ndefinition : A neurenteric cyst located in the spine.\nsynonyms :\n'}


{'id': 'HP_0030727', 'url': 'http://purl.obolibrary.org/obo/HP_0030727', 'lbl': 'Intracranial neurenteric cyst', 'desc': 'label: Intracranial neurenteric cyst\ndefinition : A neurenteric cyst located within the skull.\nsynonyms :\n'}


{'id': 'HP_0030728', 'url': 'http://purl.obolibrary.org/obo/HP_0030728', 'lbl': 'Meromelia', 'desc': 'label: Meromelia\ndefinition : Partial absence of a free limb (excluding girdle). It can refer to the proximal, middle or distal segment of the upper or lower limb. The deficiency may be transverse or longitudinal. Thus, meromelia is a lack of a part, but not all, of one or more limbs with the presence of a hand or foot.\nsynonyms :\n'}


{'id': 'HP_0030729', 'url': 'http://purl.obolibrary.org/obo/HP_0030729', 'lbl': 'Frontoethmoidal meningocele', 'desc': 'label: Frontoethmoidal meningocele\ndefinition : A herniation of meninges through a congenital bone defect in the skull at the junction of the frontal and ethmoidal bones.\nsynonyms :Frontoethmoid meningocele\n'}


{'id': 'HP_0030730', 'url': 'http://purl.obolibrary.org/obo/HP_0030730', 'lbl': 'Parietal meningocele', 'desc': 'label: Parietal meningocele\ndefinition : A herniation of meninges through a congenital bone defect in the skull in the parietal region.\nsynonyms :\n'}


{'id': 'HP_0030731', 'url': 'http://purl.obolibrary.org/obo/HP_0030731', 'lbl': 'Carcinoma', 'desc': 'label: Carcinoma\ndefinition : A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus).\nsynonyms :\n'}


{'id': 'HP_0030732', 'url': 'http://purl.obolibrary.org/obo/HP_0030732', 'lbl': 'Dysplastic tricuspid valve', 'desc': 'label: Dysplastic tricuspid valve\ndefinition : A congenital malformation of the tricuspid valve characterized by leaflet deformation.\nsynonyms :Tricuspid valve dysplasia\n'}


{'id': 'HP_0030733', 'url': 'http://purl.obolibrary.org/obo/HP_0030733', 'lbl': 'Vesicoallantoic abdominal wall defect', 'desc': 'label: Vesicoallantoic abdominal wall defect\ndefinition : An abdominal wall defected related to a developmental anomaly of the allantois, which is an embryonic structure that develops as a diverticulum off the yolk sac at about 16 days post fertilization. During further development, the allantois becomes incorporated into the body of the embryo, connecting the ventral aspect of the urogenital sinus (which will develop into the upper pole of the urinary bladder) to the external portion of the umbilicus. Upon further development, the lumen of the allantois becomes obliterated and forms a thick fibrous cord called the urachus, which connects the apex of the bladder to the umbilicus. In adults, the urachus is known as the median umbilical ligament. Failure of the allantoic cavity to obliterate can result of one of four conditions: 1) congenital patent urachus (a completely open connection between bladder and umbilicus); 2) vesicourachal diverticulum (a diverticulum off the bladder but not communicating with the umbilicus); umbilical cyst and sinus (not communicating with the bladder); and 4) alternating urachal sinus. An abdominal wall defect can be associated with a urachal cyst.\nsynonyms :\n'}


{'id': 'HP_0030735', 'url': 'http://purl.obolibrary.org/obo/HP_0030735', 'lbl': 'Ureterovesical junction obstruction', 'desc': 'label: Ureterovesical junction obstruction\ndefinition : Blockage at the level of the bladder and the ureter caused by stenosis of the ureteral valves or failure of a narrow juxtavesical ureteral segment to dilate due to segmented fibrosis or localized absence of muscle.\nsynonyms :\n'}


{'id': 'HP_0030736', 'url': 'http://purl.obolibrary.org/obo/HP_0030736', 'lbl': 'Sacrococcygeal teratoma', 'desc': 'label: Sacrococcygeal teratoma\ndefinition : A teratoma arising in the sacro-coccygeal region.\nsynonyms :\n'}


{'id': 'HP_0030737', 'url': 'http://purl.obolibrary.org/obo/HP_0030737', 'lbl': 'Altman type I sacrococcygeal teratoma', 'desc': 'label: Altman type I sacrococcygeal teratoma\ndefinition : A type of sacrococcygeal teratoma that is predominantly external and projects from the sacrococcygeal region and presents with distortion of the buttocks.\nsynonyms :\n'}


{'id': 'HP_0030738', 'url': 'http://purl.obolibrary.org/obo/HP_0030738', 'lbl': 'Altman type II sacrococcygeal teratoma', 'desc': 'label: Altman type II sacrococcygeal teratoma\ndefinition : A type of sacrococcygeal teratoma that is predominantly external but has a large intrapelvic component.\nsynonyms :\n'}


{'id': 'HP_0030739', 'url': 'http://purl.obolibrary.org/obo/HP_0030739', 'lbl': 'Altman type III sacrococcygeal teratoma', 'desc': 'label: Altman type III sacrococcygeal teratoma\ndefinition : A type of sacrococcygeal teratoma that is predominantly intrapelvic with a small external, buttock mass.\nsynonyms :\n'}


{'id': 'HP_0030740', 'url': 'http://purl.obolibrary.org/obo/HP_0030740', 'lbl': 'Anomalous muscle bundle of the right ventricle', 'desc': 'label: Anomalous muscle bundle of the right ventricle\ndefinition : An accessory (not normally present) muscle bundle in the right ventricle which obstructs the right ventricular outflow tract.\nsynonyms :Right ventricular anomalous muscle bundle\n'}


{'id': 'HP_0030741', 'url': 'http://purl.obolibrary.org/obo/HP_0030741', 'lbl': 'Mediastinal teratoma', 'desc': 'label: Mediastinal teratoma\ndefinition : A teratoma located within the mediastinum (the cavity between the pleural sacs that contains the heart and all of the thoracic viscera except the lungs).\nsynonyms :Teratoma of the mediastinum\n'}


{'id': 'HP_0030742', 'url': 'http://purl.obolibrary.org/obo/HP_0030742', 'lbl': 'Glial remnants posterior to lens', 'desc': 'label: Glial remnants posterior to lens\ndefinition : This anomaly, also known as Mittendorf dot, is a benign, nonprogressive recognizable lesion that does not cause visual impairment. However, it can resemble a pathological congenital or acquired cataract lesion which may enlarge and cause visual impairment. The dot appears as a black speck that ranges in size from the dot made by a sharp pencil point to the size of a poppy seed. It is usually well defined, although occasionally there may be irregular, fine lines radiating outward from the dot.\nsynonyms :Mittendorf dot\n'}


{'id': 'HP_0030743', 'url': 'http://purl.obolibrary.org/obo/HP_0030743', 'lbl': 'Glial remnants anterior to the optic disc', 'desc': 'label: Glial remnants anterior to the optic disc\ndefinition : Persistance of a posterior remnant of the hyaloid artery located at the optic disc.\nsynonyms :Bergmeister papilla\n'}


{'id': 'HP_0030744', 'url': 'http://purl.obolibrary.org/obo/HP_0030744', 'lbl': 'Hyaloid vascular remnant and retrolental mass', 'desc': 'label: Hyaloid vascular remnant and retrolental mass\ndefinition : A type of persistance of the hyaloid vascular system associated with a retrolental mass that may lead to fetal cataract.\nsynonyms :\n'}


{'id': 'HP_0030745', 'url': 'http://purl.obolibrary.org/obo/HP_0030745', 'lbl': 'Dilatation of the ductus arteriosus', 'desc': 'label: Dilatation of the ductus arteriosus\ndefinition : Ductus arteriosus aneurysm (DAA) is a saccular dilatation of the ductus arteriosus. DAA can be either congenital or acquired (e.g. as a complication of surgical closure of a patent ductus arteriosus). Although the majority of patients with congenital DAA are asymptomatic and have a benign course, severe complications, such as rupture or thromboembolism, can occur. DAA is likely to emerge in the third trimester from the aortic junction of the DA, extending towards its pulmonary end.\nsynonyms :Aneurysm of the ductus arteriosus; Congenital ductus arteriosus aneurysm; Ductus arteriosus aneurysm\n'}


{'id': 'HP_0030746', 'url': 'http://purl.obolibrary.org/obo/HP_0030746', 'lbl': 'Intraventricular hemorrhage', 'desc': 'label: Intraventricular hemorrhage\ndefinition : Bleeding into the ventricles of the brain.\nsynonyms :Intraventricular haemorrhage\n'}


{'id': 'HP_0030747', 'url': 'http://purl.obolibrary.org/obo/HP_0030747', 'lbl': 'Preterm intraventricular hemorrhage', 'desc': 'label: Preterm intraventricular hemorrhage\ndefinition : Intraventricular hemorrhage that occurs in a premature infant.\nsynonyms :Preterm intraventricular haemorrhage\n'}


{'id': 'HP_0030748', 'url': 'http://purl.obolibrary.org/obo/HP_0030748', 'lbl': 'Grade I preterm intraventricular hemorrhage', 'desc': 'label: Grade I preterm intraventricular hemorrhage\ndefinition : Intraventricular hemorrhage that occurs in a preterm infant and that is restricted to subependymal region/germline matrix which is seen in the caudothalamic groove.\nsynonyms :Germinal matrix haemorrhage; Germinal matrix hemorrhage; Grade I preterm intraventricular haemorrhage\n'}


{'id': 'HP_0030749', 'url': 'http://purl.obolibrary.org/obo/HP_0030749', 'lbl': 'Grade II preterm intraventricular hemorrhage', 'desc': 'label: Grade II preterm intraventricular hemorrhage\ndefinition : Intraventricular hemorrhage that occurs in a preterm infant and that has extension into normal-sized ventricles and typically fills less than 50% of the volume of the ventricle.\nsynonyms :Grade II preterm intraventricular haemorrhage\n'}


{'id': 'HP_0030750', 'url': 'http://purl.obolibrary.org/obo/HP_0030750', 'lbl': 'Grade III preterm intraventricular hemorrhage', 'desc': 'label: Grade III preterm intraventricular hemorrhage\ndefinition : Intraventricular hemorrhage that occurs in a preterm infant and that has extension into dilated ventricles.\nsynonyms :Grade III preterm intraventricular haemorrhage\n'}


{'id': 'HP_0030751', 'url': 'http://purl.obolibrary.org/obo/HP_0030751', 'lbl': 'Grade IV preterm intraventricular hemorrhage', 'desc': 'label: Grade IV preterm intraventricular hemorrhage\ndefinition : Intraventricular hemorrhage that occurs in a preterm infant and that shows parenchymal extension.\nsynonyms :Grade IV preterm intraventricular haemorrhage\n'}


{'id': 'HP_0030752', 'url': 'http://purl.obolibrary.org/obo/HP_0030752', 'lbl': 'Dacryocystocele', 'desc': 'label: Dacryocystocele\ndefinition : A nasolacrimal duct obstruction presenting as a grey-blue cystic swelling just below the medial canthus. Believed to be a result of concomitant upper obstruction of the Rosenmuller valve and lower obstruction of the Hasner valve.\nsynonyms :Timo cyst\n'}


{'id': 'HP_0030753', 'url': 'http://purl.obolibrary.org/obo/HP_0030753', 'lbl': 'Intrauterine fetal demise of one twin after midgestation', 'desc': 'label: Intrauterine fetal demise of one twin after midgestation\ndefinition : Loss of one twin occurring after midgestation (17 weeks gestation).\nsynonyms :Intrauterine foetal demise of one twin after midgestation; Single-twin demise\n'}


{'id': 'HP_0030754', 'url': 'http://purl.obolibrary.org/obo/HP_0030754', 'lbl': 'Allantoic cyst', 'desc': "label: Allantoic cyst\ndefinition : A swelling formed at the base of umbilicus associated with a patent urachus which results from an allantoic remnant. The urachus is a fibrous remnant of the allantois which communicates from the apex of the urinary bladder to the umbilicus. Failed obliteration of the urachus can lead to various abnormalities: urachal cyst, urachal diverticulum, sinus or patent urachus - the most common type. Allantoic cysts in infants with patent urachus can be formed due to the drainage of urine into the umbilical cord, or in uncommon situations, after leakage of hypo-osmotic urine into the Wharton's jelly.\nsynonyms :\n"}


{'id': 'HP_0030755', 'url': 'http://purl.obolibrary.org/obo/HP_0030755', 'lbl': 'Craniofacial teratoma', 'desc': 'label: Craniofacial teratoma\ndefinition : A teratoma located in the craniofacial region.\nsynonyms :\n'}


{'id': 'HP_0030756', 'url': 'http://purl.obolibrary.org/obo/HP_0030756', 'lbl': 'Erythrodontia', 'desc': 'label: Erythrodontia\ndefinition : Reddish, brown opalescent discoloration of teeth in normal light.\nsynonyms :Red teeth\n'}


{'id': 'HP_0030757', 'url': 'http://purl.obolibrary.org/obo/HP_0030757', 'lbl': 'Tooth abscess', 'desc': 'label: Tooth abscess\ndefinition : A pocket of pus located within a region of a tooth.\nsynonyms :Dental abscess; Dentoalveolar abscess\n'}


{'id': 'HP_0030758', 'url': 'http://purl.obolibrary.org/obo/HP_0030758', 'lbl': 'Periapical tooth abscess', 'desc': 'label: Periapical tooth abscess\ndefinition : A tooth abscess that occurs at the tip of the root (apex) of a tooth.\nsynonyms :\n'}


{'id': 'HP_0030759', 'url': 'http://purl.obolibrary.org/obo/HP_0030759', 'lbl': 'Adipocyte hypertrophy', 'desc': 'label: Adipocyte hypertrophy\ndefinition : An increase in mean adipocyte cell size. This feature can be measured by determining the average cell diameter of adipocytes microscopically using abdominal subcutaneous adipose tissue obtained by biopsy.\nsynonyms :Fat cell hypertrophy\n'}


{'id': 'HP_0030760', 'url': 'http://purl.obolibrary.org/obo/HP_0030760', 'lbl': 'Renal fibrosis', 'desc': 'label: Renal fibrosis\ndefinition : Renal fibrosis is the consequence of an excessive accumulation of extracellular matrix that occurs in virtually every type of chronic kidney disease.\nsynonyms :Kidney fibrosis\n'}


{'id': 'HP_0030761', 'url': 'http://purl.obolibrary.org/obo/HP_0030761', 'lbl': 'obsolete Renal glomerular fibrosis', 'desc': 'label: obsolete Renal glomerular fibrosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030762', 'url': 'http://purl.obolibrary.org/obo/HP_0030762', 'lbl': 'Mesangiolysis', 'desc': 'label: Mesangiolysis\ndefinition : Partial or complete dissolution of the mesangial matrix, identified by reduced staining on a periodic acid-Schiff (PAS) or silver stain.\nsynonyms :\n'}


{'id': 'HP_0030763', 'url': 'http://purl.obolibrary.org/obo/HP_0030763', 'lbl': 'Amniotic Sheet', 'desc': 'label: Amniotic Sheet\ndefinition : A sheet like projection that can result from uterine synechiae that has been encompassed by the expanding chorion and amnion.\nsynonyms :Amniotic shelf\n'}


{'id': 'HP_0030764', 'url': 'http://purl.obolibrary.org/obo/HP_0030764', 'lbl': 'Ochronosis', 'desc': 'label: Ochronosis\ndefinition : Brown or blue-gray discoloration of the skin that can present on the axillary and inguinal areas, face, palms or soles. In addition, blue-black discoloration can be apparent on skin overlying cartilage in which the pigment is deposited, such as the ears. This is a characteristic manifestation of alkaptonuria, which is an autosomal recessively inherited deficiency of homogentisic acid oxidase that results in accumulation of homogentisic acid in collagenous structures. The sclerae are also typically involved.\nsynonyms :\n'}


{'id': 'HP_0030765', 'url': 'http://purl.obolibrary.org/obo/HP_0030765', 'lbl': 'Sleep terror', 'desc': 'label: Sleep terror\ndefinition : Episodes of intense fear, screaming and flailing although affected individuals are still asleep.\nsynonyms :Night terror; Pavor nocturnus; Sleep terrors\n'}


{'id': 'HP_0030766', 'url': 'http://purl.obolibrary.org/obo/HP_0030766', 'lbl': 'Ear pain', 'desc': 'label: Ear pain\ndefinition : Pain in the ear can be a consequence of otologic disease (primary or otogenic otalgia), or can arise from pathologic processes and structures other than the ear (secondary or referred otalgia).\nsynonyms :Ear pain; Otalgia; Pain in the ear\n'}


{'id': 'HP_0030767', 'url': 'http://purl.obolibrary.org/obo/HP_0030767', 'lbl': 'Epignathus', 'desc': 'label: Epignathus\ndefinition : Epignathus is a teratoma originating from the upper jaw, usually connected with the sphenoid bone or hard palate.\nsynonyms :Palatine teratoma\n'}


{'id': 'HP_0030769', 'url': 'http://purl.obolibrary.org/obo/HP_0030769', 'lbl': 'Exencephaly', 'desc': 'label: Exencephaly\ndefinition : A malformation of the neural tube with a large amount of protruding brain tissue and absence of calvarium.\nsynonyms :\n'}


{'id': 'HP_0030770', 'url': 'http://purl.obolibrary.org/obo/HP_0030770', 'lbl': 'Craniorachischisis', 'desc': 'label: Craniorachischisis\ndefinition : A neural tube defect in which both the brain and spinal cord remain open to varying degrees.\nsynonyms :\n'}


{'id': 'HP_0030771', 'url': 'http://purl.obolibrary.org/obo/HP_0030771', 'lbl': 'Mallet finger', 'desc': 'label: Mallet finger\ndefinition : Mallet finger refers to a condition in which the end joint of a finger bends but will not straighten by itself. In this situation, the joint can be pushed straight but will not hold that position on its own.\nsynonyms :\n'}


{'id': 'HP_0030772', 'url': 'http://purl.obolibrary.org/obo/HP_0030772', 'lbl': 'Proximal femoral focal deficiency', 'desc': 'label: Proximal femoral focal deficiency\ndefinition : Proximal femoral focal deficiency is a deformity manifested by hypoplasia of a variable portion of the femur with shortening of the entire limb.\nsynonyms :\n'}


{'id': 'HP_0030773', 'url': 'http://purl.obolibrary.org/obo/HP_0030773', 'lbl': 'Internuclear ophthalmoplegia', 'desc': 'label: Internuclear ophthalmoplegia\ndefinition : An abnormality of conjugate lateral gaze in which the affected eye shows impairment of adduction. The pathognomonic clinical sign of internuclear ophthalmoplegia is an impaired adduction while testing horizontal saccades on the side of the lesion in the ipsilateral medial longitudinal fascicule.\nsynonyms :\n'}


{'id': 'HP_0030774', 'url': 'http://purl.obolibrary.org/obo/HP_0030774', 'lbl': 'Mitochondrial swelling', 'desc': 'label: Mitochondrial swelling\ndefinition : The mitochondrial matrix refers to the substance occupying the space enclosed by the inner membrane of a mitochondrion, which contains enzymes, DNA, granules, and inclusions of protein crystals, glycogen, and lipid. Mitochondrial swelling refers to an increase in size of the mitochondrial matrix. This phenomenon is thought to be related to a permeabilized inner membrane that originates a large swelling in the mitochondrial matrix. Mitochondrial swelling may distend the outer membrane until it ruptures.\nsynonyms :\n'}


{'id': 'HP_0030775', 'url': 'http://purl.obolibrary.org/obo/HP_0030775', 'lbl': 'Modic type vertebral endplate changes', 'desc': 'label: Modic type vertebral endplate changes\ndefinition : An abnormal magnetic resonance tomography signal from a vertebral endplate according to a widely used classification published by Dr. Michael Modic.\nsynonyms :\n'}


{'id': 'HP_0030776', 'url': 'http://purl.obolibrary.org/obo/HP_0030776', 'lbl': 'Modic type I vertebral endplate changes', 'desc': 'label: Modic type I vertebral endplate changes\ndefinition : An abnormal magnetic resonance tomography signal from a vertebral endplate with a low signal on T1-weighted sequences and high signal on T2-weighted sequences. Modic type I changes are thought to represent bone marrow edema and inflammation.\nsynonyms :Modic type 1 vertebral endplate changes\n'}


{'id': 'HP_0030777', 'url': 'http://purl.obolibrary.org/obo/HP_0030777', 'lbl': 'Modic type II vertebral endplate changes', 'desc': 'label: Modic type II vertebral endplate changes\ndefinition : An abnormal magnetic resonance tomography signal from a vertebral endplate with a high signal on T1-weighted sequences and high- or isointense signal on T2 sequences. Modic type II signals are thought to indicate fatty replacement in the bone marrow.\nsynonyms :Modic type 2 vertebral endplate changes\n'}


{'id': 'HP_0030778', 'url': 'http://purl.obolibrary.org/obo/HP_0030778', 'lbl': 'Modic type III vertebral endplate changes', 'desc': 'label: Modic type III vertebral endplate changes\ndefinition : An abnormal magnetic resonance tomography signal from a vertebral endplate with a low signal on T1 and T2-weighted sequences. Modic type III signals are thought to correspond to subchondral sclerosis seen on plain radiographs.\nsynonyms :Modic type 3 vertebral endplate changes\n'}


{'id': 'HP_0030779', 'url': 'http://purl.obolibrary.org/obo/HP_0030779', 'lbl': 'Ethmocephaly', 'desc': 'label: Ethmocephaly\ndefinition : Ethmocephaly is the rarest form of holoprosencephaly, which occurs due to an incomplete cleavage of the forebrain. Clinically, the disease presents with a proboscis, hypotelorism, microphthalmos and malformed ears.\nsynonyms :\n'}


{'id': 'HP_0030780', 'url': 'http://purl.obolibrary.org/obo/HP_0030780', 'lbl': 'Abnormality of the protein C anticoagulant pathway', 'desc': 'label: Abnormality of the protein C anticoagulant pathway\ndefinition : An anomaly of the protein C anticoagulant pathway, which serves as a major system for controlling thrombosis, limiting inflammatory responses, and potentially decreasing endothelial cell apoptosis in response to inflammatory cytokines and ischemia. A natural anticoagulant system denoted the protein C pathway exerts its anticoagulant effect by regulating the activity of FVIIIa and FVa. The vitamin K-dependent protein C is the key component of the pathway. Activated protein C (APC) cleaves and inhibits coagulation cofactors FVIIIa and FVa, which result in downregulation of the activity of the coagulation system. The endothelial protein C receptor stimulates the T-TM-mediated activation of protein C on the endothelial cell surface. The two cofactors, protein S and the intact form of FV, enhance the anticoagulant activity of APC.\nsynonyms :\n'}


{'id': 'HP_0030781', 'url': 'http://purl.obolibrary.org/obo/HP_0030781', 'lbl': 'Increased circulating free fatty acid level', 'desc': 'label: Increased circulating free fatty acid level\ndefinition : A higher than normal levels of the fatty acids which can occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues.\nsynonyms :\n'}


{'id': 'HP_0030782', 'url': 'http://purl.obolibrary.org/obo/HP_0030782', 'lbl': 'Abnormal circulating interleukin concentration', 'desc': 'label: Abnormal circulating interleukin concentration\ndefinition : An abnormal amount of any of the interleukins, a class of cytokines, in the circulation.\nsynonyms :Abnormal serum IL level; Abnormal serum interleukin level\n'}


{'id': 'HP_0030783', 'url': 'http://purl.obolibrary.org/obo/HP_0030783', 'lbl': 'Increased circulating interleukin 6 concentration', 'desc': 'label: Increased circulating interleukin 6 concentration\ndefinition : An increased concentration of interleukin-6 in the blood circulation.\nsynonyms :Increased serum IL-6; Increased serum interleukin-6\n'}


{'id': 'HP_0030784', 'url': 'http://purl.obolibrary.org/obo/HP_0030784', 'lbl': 'Anomic aphasia', 'desc': 'label: Anomic aphasia\ndefinition : An inability to name people and objects that are correctly perceived. The individual is able to describe the object in question, but cannot provide the name.\nsynonyms :Amnesic aphasia; Amnestic aphasia; Anomia; Nominal aphasia; Word-finding difficulty\n'}


{'id': 'HP_0030785', 'url': 'http://purl.obolibrary.org/obo/HP_0030785', 'lbl': 'Mediastinal cystic lymphangioma', 'desc': 'label: Mediastinal cystic lymphangioma\ndefinition : A lymphangioma (congenital malformation consisting of focal proliferations of well-differentiated lymphatic tissue in multi cystic or sponge like structures) located within the mediastinum, i.e., the central compartment of the thoracic cavity that is surrounded by loose connective tissue. Mediastinal lymphangioma is a slow growing mass with benign features, and accounts for 1% of all mediastinal tumors.\nsynonyms :Intrathoracic cystic hygroma; Thoracic cystic lymphangioma\n'}


{'id': 'HP_0030786', 'url': 'http://purl.obolibrary.org/obo/HP_0030786', 'lbl': 'Photopsia', 'desc': 'label: Photopsia\ndefinition : Perceived flashes of light.\nsynonyms :\n'}


{'id': 'HP_0030787', 'url': 'http://purl.obolibrary.org/obo/HP_0030787', 'lbl': 'Cerumen abnormality', 'desc': 'label: Cerumen abnormality\ndefinition : Any anomaly of the cerumen (ear wax), the yellowish waxy substance secreted in the ear canal.\nsynonyms :\n'}


{'id': 'HP_0030788', 'url': 'http://purl.obolibrary.org/obo/HP_0030788', 'lbl': 'Impacted cerumen', 'desc': 'label: Impacted cerumen\ndefinition : Blockage of the external auditory canal by a buildup of earwax.\nsynonyms :\n'}


{'id': 'HP_0030789', 'url': 'http://purl.obolibrary.org/obo/HP_0030789', 'lbl': 'Excessive cerumen', 'desc': 'label: Excessive cerumen\ndefinition : An increased quantity of earwax.\nsynonyms :\n'}


{'id': 'HP_0030790', 'url': 'http://purl.obolibrary.org/obo/HP_0030790', 'lbl': 'Abnormal cerumen color', 'desc': 'label: Abnormal cerumen color\ndefinition : An anomolous earwax color. Earwax (cerumen) is usually light to dark brown or orange in color.\nsynonyms :Abnormal cerumen colour; Abnormal cerumen pigmentation\n'}


{'id': 'HP_0030791', 'url': 'http://purl.obolibrary.org/obo/HP_0030791', 'lbl': 'Abnormal jaw morphology', 'desc': 'label: Abnormal jaw morphology\ndefinition : A structural anomaly of the jaw, the bony structure of the mouth that consists of the mandible and the maxilla.\nsynonyms :\n'}


{'id': 'HP_0030792', 'url': 'http://purl.obolibrary.org/obo/HP_0030792', 'lbl': 'Jaw neoplasm', 'desc': 'label: Jaw neoplasm\ndefinition : A tumor originating in the jaw (mandible or maxilla).\nsynonyms :\n'}


{'id': 'HP_0030793', 'url': 'http://purl.obolibrary.org/obo/HP_0030793', 'lbl': 'Jaw swelling', 'desc': 'label: Jaw swelling\ndefinition : Abnormal enlargement in the upper jaw (maxilla) or in the lower jaw (mandible).\nsynonyms :\n'}


{'id': 'HP_0030794', 'url': 'http://purl.obolibrary.org/obo/HP_0030794', 'lbl': 'Abnormal circulating C-peptide concentration', 'desc': 'label: Abnormal circulating C-peptide concentration\ndefinition : An anomolous circulating concentration of the connecting (C) peptide, which links the insulin A and B chains in proinsulin, providing thereby a means to promote their efficient folding and assembly in the endoplasmic reticulum during insulin biosynthesis. After cleavage of proinsulin, C-peptide is stored with insulin in the soluble phase of the secretory granules and is subsequently released in equimolar amounts with insulin, providing a useful independent indicator of insulin secretion.\nsynonyms :Abnormal C peptide level; Abnormal C-peptide level\n'}


{'id': 'HP_0030795', 'url': 'http://purl.obolibrary.org/obo/HP_0030795', 'lbl': 'Reduced C-peptide level', 'desc': 'label: Reduced C-peptide level\ndefinition : A decreased concentration of C-peptide in the circulation. Since C-peptide is secreted in equimolar amounts to insulin, this feature correlates with reduced insulin secretion.\nsynonyms :Reduced C peptide level\n'}


{'id': 'HP_0030796', 'url': 'http://purl.obolibrary.org/obo/HP_0030796', 'lbl': 'Increased C-peptide level', 'desc': 'label: Increased C-peptide level\ndefinition : An elevated concentration of C-peptide in the circulation. Since C-peptide is secreted in equimolar amounts to insulin, this feature correlates with increased insulin secretion.\nsynonyms :Increased C peptide level\n'}


{'id': 'HP_0030797', 'url': 'http://purl.obolibrary.org/obo/HP_0030797', 'lbl': 'Reduced volume of central subdivision of bed nucleus of stria terminalis', 'desc': 'label: Reduced volume of central subdivision of bed nucleus of stria terminalis\ndefinition : A diminished volume of the central part of the bed nucleus of the stria terminalis.\nsynonyms :\n'}


{'id': 'HP_0030798', 'url': 'http://purl.obolibrary.org/obo/HP_0030798', 'lbl': 'Abnormality of the bed nucleus of stria terminalis', 'desc': 'label: Abnormality of the bed nucleus of stria terminalis\ndefinition : The stria terminalis is a slender, compact fiber bundle that connects the amygdala (amygdaloid body) with the hypothalamus and other basal forebrain regions. The bed nucleus of the stria terminalis is a limbic forebrain structure that receives heavy projections from, among other areas, the basolateral amygdala, and projects in turn to hypothalamic and brainstem target areas that mediate many of the autonomic and behavioral responses to aversive or threatening stimuli. This term refers to an anomaly of the bed nucleus.\nsynonyms :\n'}


{'id': 'HP_0030799', 'url': 'http://purl.obolibrary.org/obo/HP_0030799', 'lbl': 'Scaphocephaly', 'desc': 'label: Scaphocephaly\ndefinition : Scaphocephaly is a subtype of dolichocephaly where the anterior and posterior aspects of the cranial vault are pointed (boat-shaped). Scaphocephaly is caused by a precocious fusion of sagittal suture without other associated synostosis.\nsynonyms :\n'}


{'id': 'HP_0030800', 'url': 'http://purl.obolibrary.org/obo/HP_0030800', 'lbl': 'Abnormal visual accommodation', 'desc': 'label: Abnormal visual accommodation\ndefinition : An anomaly in the process of visual accommodation, which is the process of adjustment of the eye to enable sharp vision of objects at different distances. Accommodation is mediated by contraction of the ciliary muscles, which alter the convexity of the lens and, consequently, its refractive power.\nsynonyms :\n'}


{'id': 'HP_0030801', 'url': 'http://purl.obolibrary.org/obo/HP_0030801', 'lbl': 'Reduced visual accommodation', 'desc': 'label: Reduced visual accommodation\ndefinition : A decreased ability of the eye to adjust and thereby enable sharp vision of objects at different distances.\nsynonyms :\n'}


{'id': 'HP_0030802', 'url': 'http://purl.obolibrary.org/obo/HP_0030802', 'lbl': 'Lower eyelid retraction', 'desc': 'label: Lower eyelid retraction\ndefinition : Inferior malposition of the lower eyelid margin without eyelid eversion.\nsynonyms :\n'}


{'id': 'HP_0030803', 'url': 'http://purl.obolibrary.org/obo/HP_0030803', 'lbl': 'Platonychia', 'desc': 'label: Platonychia\ndefinition : Abnormal flat nail.\nsynonyms :\n'}


{'id': 'HP_0030804', 'url': 'http://purl.obolibrary.org/obo/HP_0030804', 'lbl': 'Trachyonychia', 'desc': 'label: Trachyonychia\ndefinition : Excessive longitudinal ridging that gives the surface of the nail plate a rough appearance. It results from multiple foci of defective keratinization of the proximal nail matrix.\nsynonyms :\n'}


{'id': 'HP_0030805', 'url': 'http://purl.obolibrary.org/obo/HP_0030805', 'lbl': 'Absent lunula', 'desc': 'label: Absent lunula\ndefinition : Lack of the lunula at the base of a nail. The lunula is the crescent-shaped whitish area of the bed of a fingernail or toenail.\nsynonyms :Absent lunulae; Lunula absent; Lunulae absent\n'}


{'id': 'HP_0030806', 'url': 'http://purl.obolibrary.org/obo/HP_0030806', 'lbl': 'Fast-growing nails', 'desc': 'label: Fast-growing nails\ndefinition : Nails whose growth is quicker than normal.\nsynonyms :\n'}


{'id': 'HP_0030807', 'url': 'http://purl.obolibrary.org/obo/HP_0030807', 'lbl': 'Abnormal nail growth', 'desc': 'label: Abnormal nail growth\ndefinition : Nail whose growth pattern or speed deviates from normal.\nsynonyms :\n'}


{'id': 'HP_0030808', 'url': 'http://purl.obolibrary.org/obo/HP_0030808', 'lbl': 'Ragged cuticle', 'desc': 'label: Ragged cuticle\ndefinition : The cuticle (properly known as the eponychium, or the medial nail fold or the proximal nail fold), is the thickened layer of skin surrounding fingernails and toenails. Its function is to protect the area between the nail and epidermis from exposure to bacteria. This term refers to the presence of and irregular edge or outline of the cuticle.\nsynonyms :\n'}


{'id': 'HP_0030809', 'url': 'http://purl.obolibrary.org/obo/HP_0030809', 'lbl': 'Abnormal tongue morphology', 'desc': 'label: Abnormal tongue morphology\ndefinition : Any structural anomaly of the tongue.\nsynonyms :\n'}


{'id': 'HP_0030810', 'url': 'http://purl.obolibrary.org/obo/HP_0030810', 'lbl': 'Abnormal tongue physiology', 'desc': 'label: Abnormal tongue physiology\ndefinition : Any functional anomaly of the tongue.\nsynonyms :\n'}


{'id': 'HP_0030811', 'url': 'http://purl.obolibrary.org/obo/HP_0030811', 'lbl': 'Tongue pain', 'desc': 'label: Tongue pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the tongue.\nsynonyms :Painful tongue\n'}


{'id': 'HP_0030812', 'url': 'http://purl.obolibrary.org/obo/HP_0030812', 'lbl': 'Enlarged tonsils', 'desc': 'label: Enlarged tonsils\ndefinition : Increase in size of the tonsils, small collections of lymphoid tissue facing into the aerodigestive tract on either side of the back part of the throat.\nsynonyms :Enlargment of tonsils; Tonsillar hypertrophy; tonsils large/hypertrophy\n'}


{'id': 'HP_0030813', 'url': 'http://purl.obolibrary.org/obo/HP_0030813', 'lbl': 'Absent tonsils', 'desc': 'label: Absent tonsils\ndefinition : Lack of observable tonsillar tissue.\nsynonyms :Hypoplastic tonsils; Tonsillar hypoplasia\n'}


{'id': 'HP_0030814', 'url': 'http://purl.obolibrary.org/obo/HP_0030814', 'lbl': 'Orange discolored tonsils', 'desc': 'label: Orange discolored tonsils\ndefinition : A phenomenon of orange colored oral tonsils. This feature is characteristic of Tangier disease and illustrated will by Figure 1 of PMID:19470903.\nsynonyms :Orange colored tonsils; Orange coloured tonsils; Orange discoloured tonsils; Orange tonsils; Tonsils with orange deposits\n'}


{'id': 'HP_0030815', 'url': 'http://purl.obolibrary.org/obo/HP_0030815', 'lbl': 'Lipoma of the tongue', 'desc': 'label: Lipoma of the tongue\ndefinition : A lipoma localized to the tongue. May present as a nontender, soft, spherical mass of the tongue.\nsynonyms :Tongue lipoma\n'}


{'id': 'HP_0030816', 'url': 'http://purl.obolibrary.org/obo/HP_0030816', 'lbl': 'Gingival recession', 'desc': 'label: Gingival recession\ndefinition : The loss of gum tissue. The result is that gum tissue is recessed and its position on the tooth is lowered, exposing the roots of the teeth.\nsynonyms :Gum recession; Receding gums\n'}


{'id': 'HP_0030817', 'url': 'http://purl.obolibrary.org/obo/HP_0030817', 'lbl': 'Beaked nails', 'desc': 'label: Beaked nails\ndefinition : Severe nail curvature, causing the tip of the nail to point downwards with respect to the axis of the finger. Beaked nails are caused by resorption of the distal digit.\nsynonyms :\n'}


{'id': 'HP_0030818', 'url': 'http://purl.obolibrary.org/obo/HP_0030818', 'lbl': 'Central nail canal', 'desc': 'label: Central nail canal\ndefinition : The presence of a depressed line ("canal") in the center of the nail.\nsynonyms :Median nail dystrophy\n'}


{'id': 'HP_0030819', 'url': 'http://purl.obolibrary.org/obo/HP_0030819', 'lbl': 'Ski jump nail', 'desc': 'label: Ski jump nail\ndefinition : Nails that slope upward at the free edge.\nsynonyms :Upslanting nail; Upward angulation of nail\n'}


{'id': 'HP_0030820', 'url': 'http://purl.obolibrary.org/obo/HP_0030820', 'lbl': 'Hooded eyelid', 'desc': 'label: Hooded eyelid\ndefinition : Eyelid partly covered by skin when eyes are open.\nsynonyms :\n'}


{'id': 'HP_0030821', 'url': 'http://purl.obolibrary.org/obo/HP_0030821', 'lbl': 'Hooded lower eyelid', 'desc': 'label: Hooded lower eyelid\ndefinition : Lower eyelid partly covered by skin when eyes are open.\nsynonyms :\n'}


{'id': 'HP_0030822', 'url': 'http://purl.obolibrary.org/obo/HP_0030822', 'lbl': 'Hooded upper eyelid', 'desc': 'label: Hooded upper eyelid\ndefinition : Upper eyelid partly covered by skin when eyes are open.\nsynonyms :\n'}


{'id': 'HP_0030823', 'url': 'http://purl.obolibrary.org/obo/HP_0030823', 'lbl': 'Scleral thickening', 'desc': 'label: Scleral thickening\ndefinition : Increased dimension of the sclera in the anterior-posterior axis.\nsynonyms :Thick sclera\n'}


{'id': 'HP_0030824', 'url': 'http://purl.obolibrary.org/obo/HP_0030824', 'lbl': 'Mizuo phenomenon', 'desc': 'label: Mizuo phenomenon\ndefinition : Change in the color of the fundus from red in the dark-adapted state to golden immediately or shortly after the onset of the light. The color of the fundus reflex in the light adapted state has also been described as golden-yellow, gray-white, and yellow-white. This reflex can appear either homogeneous or in streaks in the fundus. The retinal vessels appear to be protruding in contrast to the radiant background. Dark adaptation leads to disappearance of the unusual fundus coloration [Digital Journal of Ophthalmology 2008; Volume 14, Number 14].\nsynonyms :Mizuo-Nakamura phenomenon\n'}


{'id': 'HP_0030825', 'url': 'http://purl.obolibrary.org/obo/HP_0030825', 'lbl': 'Absent foveal reflex', 'desc': 'label: Absent foveal reflex\ndefinition : Lack of the foveal reflex, which normally occurs as a result of the reflection of light from the ophthalmoscope in the foveal pit upon examination. The foveal reflex is a bright pinpoint of light that is observed to move sideways or up and down in response to movement of the opthalmoscope.\nsynonyms :Foveal reflex absent; Loss of foveal reflex\n'}


{'id': 'HP_0030826', 'url': 'http://purl.obolibrary.org/obo/HP_0030826', 'lbl': 'Eyelid fasciculation', 'desc': 'label: Eyelid fasciculation\ndefinition : Tiny, repetitive muscle contractions in the eyelids, causing the appearance of twitching.\nsynonyms :Eyelid fluttering; Fasciculation of the eyelid; Muscle twitches in eye lid; Muscle twitches in eyelid; Twitching around eyes\n'}


{'id': 'HP_0030828', 'url': 'http://purl.obolibrary.org/obo/HP_0030828', 'lbl': 'Wheezing', 'desc': 'label: Wheezing\ndefinition : A high-pitched whistling sound associated with labored breathing.\nsynonyms :Wheezing\n'}


{'id': 'HP_0030829', 'url': 'http://purl.obolibrary.org/obo/HP_0030829', 'lbl': 'Abnormal breath sound', 'desc': 'label: Abnormal breath sound\ndefinition : An anomalous (adventitious) sound produced by the breathing process.\nsynonyms :Abnormal lung auscultation finding\n'}


{'id': 'HP_0030830', 'url': 'http://purl.obolibrary.org/obo/HP_0030830', 'lbl': 'Crackles', 'desc': 'label: Crackles\ndefinition : Crackles are discontinuous, explosive, and nonmusical adventitious lung sounds normally heard in inspiration and sometimes during expiration. Crackles are usually classified as fine and coarse crackles based on their duration, loudness, pitch, timing in the respiratory cycle, and relationship to coughing and changing body position.\nsynonyms :Crepitations; Rales\n'}


{'id': 'HP_0030831', 'url': 'http://purl.obolibrary.org/obo/HP_0030831', 'lbl': 'Rhonchi', 'desc': 'label: Rhonchi\ndefinition : Abnormal breath sounds characterized by low-pitched, snoring or rattle-like sounds.\nsynonyms :\n'}


{'id': 'HP_0030832', 'url': 'http://purl.obolibrary.org/obo/HP_0030832', 'lbl': 'Vitreous strands', 'desc': 'label: Vitreous strands\ndefinition : Fiber- or rope-like opacities located within the vitreous humor.\nsynonyms :\n'}


{'id': 'HP_0030833', 'url': 'http://purl.obolibrary.org/obo/HP_0030833', 'lbl': 'Neck pain', 'desc': 'label: Neck pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the neck.\nsynonyms :Neck pain\n'}


{'id': 'HP_0030834', 'url': 'http://purl.obolibrary.org/obo/HP_0030834', 'lbl': 'Shoulder pain', 'desc': 'label: Shoulder pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the shoulder.\nsynonyms :Shoulder pain\n'}


{'id': 'HP_0030835', 'url': 'http://purl.obolibrary.org/obo/HP_0030835', 'lbl': 'Elbow pain', 'desc': 'label: Elbow pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the elbow.\nsynonyms :Elbow pain\n'}


{'id': 'HP_0030836', 'url': 'http://purl.obolibrary.org/obo/HP_0030836', 'lbl': 'Wrist pain', 'desc': 'label: Wrist pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the wrist.\nsynonyms :Wrist pain\n'}


{'id': 'HP_0030837', 'url': 'http://purl.obolibrary.org/obo/HP_0030837', 'lbl': 'Finger pain', 'desc': 'label: Finger pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the finger.\nsynonyms :Finger pain\n'}


{'id': 'HP_0030838', 'url': 'http://purl.obolibrary.org/obo/HP_0030838', 'lbl': 'Hip pain', 'desc': 'label: Hip pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the hip.\nsynonyms :Hip pain\n'}


{'id': 'HP_0030839', 'url': 'http://purl.obolibrary.org/obo/HP_0030839', 'lbl': 'Knee pain', 'desc': 'label: Knee pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the knee.\nsynonyms :Pain under knee cap; Knee pain\n'}


{'id': 'HP_0030840', 'url': 'http://purl.obolibrary.org/obo/HP_0030840', 'lbl': 'Ankle pain', 'desc': 'label: Ankle pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the ankle.\nsynonyms :Ankle pain\n'}


{'id': 'HP_0030841', 'url': 'http://purl.obolibrary.org/obo/HP_0030841', 'lbl': 'Toe pain', 'desc': 'label: Toe pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the toe.\nsynonyms :Toe pain\n'}


{'id': 'HP_0030842', 'url': 'http://purl.obolibrary.org/obo/HP_0030842', 'lbl': 'Choking episodes', 'desc': 'label: Choking episodes\ndefinition : Incidents in which a piece of food or other objects get stuck in the upper airway and provoke coughing, gagging, inability to talk, and difficulty breathing.\nsynonyms :\n'}


{'id': 'HP_0030843', 'url': 'http://purl.obolibrary.org/obo/HP_0030843', 'lbl': 'Cardiac amyloidosis', 'desc': 'label: Cardiac amyloidosis\ndefinition : Extracellular deposition in cardiac tissue of a proteinaceous material that, when stained with Congo red, demonstrates apple-green birefringence under polarized light and that has a distinct color when stained with sulfated Alcian blue. Viewed with electron microscopy, the amyloid deposits are seen to be composed of a beta-sheet fibrillar material. These nonbranching fibrils have a diameter of 7.5 to 10 nm and are the result of protein misfolding.\nsynonyms :Amyloid cardiomyopathy\n'}


{'id': 'HP_0030844', 'url': 'http://purl.obolibrary.org/obo/HP_0030844', 'lbl': 'Undetectable pattern electroretinogram', 'desc': 'label: Undetectable pattern electroretinogram\ndefinition : Absent response to a pattern electroretinogram (PERG).\nsynonyms :\n'}


{'id': 'HP_0030845', 'url': 'http://purl.obolibrary.org/obo/HP_0030845', 'lbl': 'Heliotrope rash of eyelid', 'desc': 'label: Heliotrope rash of eyelid\ndefinition : Heliotrope rash is a violaceous discoloration of the eyelids associated with periorbital edema.\nsynonyms :\n'}


{'id': 'HP_0030846', 'url': 'http://purl.obolibrary.org/obo/HP_0030846', 'lbl': 'Abnormality of venous physiology', 'desc': 'label: Abnormality of venous physiology\ndefinition : An anomaly of venous function.\nsynonyms :\n'}


{'id': 'HP_0030847', 'url': 'http://purl.obolibrary.org/obo/HP_0030847', 'lbl': 'Abnormal jugular venous pressure', 'desc': 'label: Abnormal jugular venous pressure\ndefinition : An anomaly of the jugular venous pressure. The internal jugular veins, being continuous with the superior vena cava, provide a visible measure of the degree to which the systemic venous reservoir is filled. The vertical height above the right atrium to which they are distended and above which they are in a collapsed state provides an imperfect reflection of the right atrial pressure.\nsynonyms :\n'}


{'id': 'HP_0030848', 'url': 'http://purl.obolibrary.org/obo/HP_0030848', 'lbl': 'Elevated jugular venous pressure', 'desc': 'label: Elevated jugular venous pressure\ndefinition : Increased jugular venous pressure.\nsynonyms :\n'}


{'id': 'HP_0030849', 'url': 'http://purl.obolibrary.org/obo/HP_0030849', 'lbl': 'Hepatojugular reflux', 'desc': 'label: Hepatojugular reflux\ndefinition : The examiner applies firm but persistent pressure over the liver for 10 seconds while observing the mean jugular venous pressure. Normally there is either no rise or only a transient (i.e., 2 to 3 sec) rise in mean jugular venous pressure. A sustained increase in the mean venous pressure until abdominal compression is released is abnormal and indicates impaired right heart function. This abnormal response is called hepatojugular reflux.\nsynonyms :\n'}


{'id': 'HP_0030850', 'url': 'http://purl.obolibrary.org/obo/HP_0030850', 'lbl': 'Abnormal pulse pressure', 'desc': 'label: Abnormal pulse pressure\ndefinition : An anomaly of the pulse pressure, which is defined as the systolic pressured minus the diastolic pressure.\nsynonyms :\n'}


{'id': 'HP_0030851', 'url': 'http://purl.obolibrary.org/obo/HP_0030851', 'lbl': 'Low pulse pressure', 'desc': 'label: Low pulse pressure\ndefinition : Reduced amplitude of the pulse pressure (systolic blood pressure minus diastolic blood pressure).\nsynonyms :\n'}


{'id': 'HP_0030852', 'url': 'http://purl.obolibrary.org/obo/HP_0030852', 'lbl': 'High pulse pressure', 'desc': 'label: High pulse pressure\ndefinition : Increased amplitude of the pulse pressure (systolic blood pressure minus diastolic blood pressure).\nsynonyms :\n'}


{'id': 'HP_0030853', 'url': 'http://purl.obolibrary.org/obo/HP_0030853', 'lbl': 'Heterotaxy', 'desc': 'label: Heterotaxy\ndefinition : An abnormality in which the internal thoraco-abdominal organs demonstrate abnormal arrangement across the left-right axis of the body.\nsynonyms :Heterotaxia\n'}


{'id': 'HP_0030854', 'url': 'http://purl.obolibrary.org/obo/HP_0030854', 'lbl': 'Scleral staphyloma', 'desc': 'label: Scleral staphyloma\ndefinition : A staphyloma is a localized defect in the eye wall with protrusion of uveal tissue due to alterations in scleral thickness and structure.\nsynonyms :Staphyloma\n'}


{'id': 'HP_0030855', 'url': 'http://purl.obolibrary.org/obo/HP_0030855', 'lbl': 'Anterior staphyloma', 'desc': 'label: Anterior staphyloma\ndefinition : A localized defect in the anterior eye wall with protrusion of uveal tissue due to alterations in scleral thickness and structure.\nsynonyms :\n'}


{'id': 'HP_0030856', 'url': 'http://purl.obolibrary.org/obo/HP_0030856', 'lbl': 'Posterior staphyloma', 'desc': 'label: Posterior staphyloma\ndefinition : A localized defect in the posterior eye wall with protrusion of uveal tissue due to alterations in scleral thickness and structure.\nsynonyms :\n'}


{'id': 'HP_0030857', 'url': 'http://purl.obolibrary.org/obo/HP_0030857', 'lbl': 'Eye movement-induced pain', 'desc': 'label: Eye movement-induced pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the eye that is worse in certain directions of gaze and during prolonged gaze holding.\nsynonyms :\n'}


{'id': 'HP_0030858', 'url': 'http://purl.obolibrary.org/obo/HP_0030858', 'lbl': 'Addictive behavior', 'desc': "label: Addictive behavior\ndefinition : When an activity, substance, object, or behavior becomes the main focus of a person's life excluding other activities, or has begun to harm the individual or others physically, mentally, or socially can be considered addictive behavior. A person can become addicted or compulsively engaged with anything.\nsynonyms :Addictive behaviour\n"}


{'id': 'HP_0030859', 'url': 'http://purl.obolibrary.org/obo/HP_0030859', 'lbl': 'Anti-topoisomerase I antibody positivity', 'desc': 'label: Anti-topoisomerase I antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against topoisomerase I.\nsynonyms :Anti-Scl-70 antibody positivity; Top1 antibody positivity; Topoisomerase (DNA) I antibody positivity\n'}


{'id': 'HP_0030860', 'url': 'http://purl.obolibrary.org/obo/HP_0030860', 'lbl': 'Abnormal CSF amyloid concentration', 'desc': 'label: Abnormal CSF amyloid concentration\ndefinition : Abnormal concentration of amyloid in the cerebrospinal fluid (CSF).\nsynonyms :Abnormal CSF A[beta]42 level; Abnormal CSF amyloid level\n'}


{'id': 'HP_0030861', 'url': 'http://purl.obolibrary.org/obo/HP_0030861', 'lbl': 'Decreased CSF amyloid concentration', 'desc': 'label: Decreased CSF amyloid concentration\ndefinition : Reduced concentration of amyloid in the cerebrospinal fluid (CSF).\nsynonyms :Decreased CSF amyloid level\n'}


{'id': 'HP_0030862', 'url': 'http://purl.obolibrary.org/obo/HP_0030862', 'lbl': 'Elevated CSF amyloid concentration', 'desc': 'label: Elevated CSF amyloid concentration\ndefinition : Increased concentration of amyloid in the cerebrospinal fluid (CSF).\nsynonyms :Elevated CSF amyloid level\n'}


{'id': 'HP_0030863', 'url': 'http://purl.obolibrary.org/obo/HP_0030863', 'lbl': 'Nasal flaring', 'desc': 'label: Nasal flaring\ndefinition : Widening of the nostrils upon inhalation as a manifestation of respiratory distress.\nsynonyms :\n'}


{'id': 'HP_0030864', 'url': 'http://purl.obolibrary.org/obo/HP_0030864', 'lbl': 'Intercostal retractions', 'desc': 'label: Intercostal retractions\ndefinition : A pulling inward of the soft tissues between the ribs upon inhalation. This is a sign of increased use of the chest muscles for breathing and is a manifestation of respiratory distress.\nsynonyms :Chest retractions\n'}


{'id': 'HP_0030865', 'url': 'http://purl.obolibrary.org/obo/HP_0030865', 'lbl': 'Large elbow', 'desc': 'label: Large elbow\ndefinition : Abnormal increased size of the elbow joint.\nsynonyms :Prominent elbow\n'}


{'id': 'HP_0030866', 'url': 'http://purl.obolibrary.org/obo/HP_0030866', 'lbl': 'Large knee', 'desc': 'label: Large knee\ndefinition : Abnormally increased size of the knee joint.\nsynonyms :\n'}


{'id': 'HP_0030867', 'url': 'http://purl.obolibrary.org/obo/HP_0030867', 'lbl': 'Vertical orbital dystopia', 'desc': 'label: Vertical orbital dystopia\ndefinition : The orbits do not lie on the same horizontal plane, that is, one eye is lower than the other.\nsynonyms :Eyes at different heights; Misaligned eyes; Unequal eye height\n'}


{'id': 'HP_0030868', 'url': 'http://purl.obolibrary.org/obo/HP_0030868', 'lbl': 'Monorchism', 'desc': 'label: Monorchism\ndefinition : Having only one testis in the scrotum.\nsynonyms :Monorchidism\n'}


{'id': 'HP_0030869', 'url': 'http://purl.obolibrary.org/obo/HP_0030869', 'lbl': 'Anorchism', 'desc': 'label: Anorchism\ndefinition : An abnormality of XY sexual development characterized by the absence of both testes at birth.\nsynonyms :\n'}


{'id': 'HP_0030870', 'url': 'http://purl.obolibrary.org/obo/HP_0030870', 'lbl': 'Abnormality of spinal facet joint', 'desc': 'label: Abnormality of spinal facet joint\ndefinition : An anomaly of the small joints located between and behind adjacent vertebrae.\nsynonyms :Abnormality of Z-joint; Abnormality of apophyseal joint; Abnormality of zygapophyseal joint; Abnormality of zygapophysial joint\n'}


{'id': 'HP_0030871', 'url': 'http://purl.obolibrary.org/obo/HP_0030871', 'lbl': 'Facet joint arthrosis', 'desc': 'label: Facet joint arthrosis\ndefinition : Osteoarthritis of facet joints in the spine. Degeneration of cartilage in the facet joints results in bone rubbing on bone and reactive new bone formation visible on X-ray.\nsynonyms :Facet arthritis\n'}


{'id': 'HP_0030872', 'url': 'http://purl.obolibrary.org/obo/HP_0030872', 'lbl': 'Abnormal cardiac ventricular function', 'desc': 'label: Abnormal cardiac ventricular function\ndefinition : An abnormality of the cardiac ventricular function.\nsynonyms :\n'}


{'id': 'HP_0030873', 'url': 'http://purl.obolibrary.org/obo/HP_0030873', 'lbl': 'Anti-centromere antibody positivity', 'desc': 'label: Anti-centromere antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against the centromeres or centromere components.\nsynonyms :ACA positivity; Anticentromere antibody positivity\n'}


{'id': 'HP_0030874', 'url': 'http://purl.obolibrary.org/obo/HP_0030874', 'lbl': 'Oxygen desaturation on exertion', 'desc': 'label: Oxygen desaturation on exertion\ndefinition : Oxygen saturation less than 95% on exertion or arterial partial pressure of oxygen falling by more than 1kPa.\nsynonyms :O2 desaturation on exertion\n'}


{'id': 'HP_0030875', 'url': 'http://purl.obolibrary.org/obo/HP_0030875', 'lbl': 'Abnormality of pulmonary circulation', 'desc': 'label: Abnormality of pulmonary circulation\ndefinition : A functional anomaly of that portion of the cardiosvascular system that carries deoxygenated blood from the heart to the lungs and returns oxygenated blood back to the heart.\nsynonyms :Abnormal pulmonary circulation; Abnormality of respiratory circulation\n'}


{'id': 'HP_0030876', 'url': 'http://purl.obolibrary.org/obo/HP_0030876', 'lbl': 'Increased pulmonary capillary wedge pressure', 'desc': 'label: Increased pulmonary capillary wedge pressure\ndefinition : Pulmonary capillary wedge pressure (PCWP) above 15mmHg.\nsynonyms :Increased pulmonary arterial wedge pressure; Increased pulmonary artery occlusion pressure\n'}


{'id': 'HP_0030877', 'url': 'http://purl.obolibrary.org/obo/HP_0030877', 'lbl': 'Reduced FEV1/FVC ratio', 'desc': 'label: Reduced FEV1/FVC ratio\ndefinition : Abnormally low FEV1/FVC (FEV1 - forced expiratory volume in 1 second; FVC forced vital capacity).\nsynonyms :Obstructive deficit on pulmonary function test; Obstructive deficit on pulmonary function testing\n'}


{'id': 'HP_0030878', 'url': 'http://purl.obolibrary.org/obo/HP_0030878', 'lbl': 'Abnormality on pulmonary function testing', 'desc': 'label: Abnormality on pulmonary function testing\ndefinition : Any anomaly measure by pulmonary function testing, which includes spirometry, measures of diffusing capacity, and plethysmography.\nsynonyms :Abnormal pulmonary function test; Abnormal spirometry test\n'}


{'id': 'HP_0030879', 'url': 'http://purl.obolibrary.org/obo/HP_0030879', 'lbl': 'Interlobular septal thickening', 'desc': 'label: Interlobular septal thickening\ndefinition : Presence of thickening of the interlobular septa of the lungs as seen on a CT scan.\nsynonyms :Interlobular lines (pulmonary CT finding); Peripheral lines (pulmonary CT finding); Septal lines (pulmonary CT finding); Septal thickening (pulmonary CT finding); Short lines (pumonary CT finding); Interlobular septal thickening on pulmonary HRCT\n'}


{'id': 'HP_0030880', 'url': 'http://purl.obolibrary.org/obo/HP_0030880', 'lbl': 'Raynaud phenomenon', 'desc': "label: Raynaud phenomenon\ndefinition : \nsynonyms :Raynaud's phenomenon; Raynaud disease\n"}


{'id': 'HP_0030881', 'url': 'http://purl.obolibrary.org/obo/HP_0030881', 'lbl': 'Shoulder impingement', 'desc': 'label: Shoulder impingement\ndefinition : Trapping and compression of the rotator cuff tendons during shoulder movements.\nsynonyms :\n'}


{'id': 'HP_0030882', 'url': 'http://purl.obolibrary.org/obo/HP_0030882', 'lbl': 'Coronary artery aneurysm', 'desc': 'label: Coronary artery aneurysm\ndefinition : Enlargement of the diameter (cross-section) of a coronary artery as defined by a focal dilation of a segment at least 1.5 times larger than the reference vessel.\nsynonyms :Coronary arterial dilatation; Coronary artery dilatation; Coronary artery ectasia\n'}


{'id': 'HP_0030883', 'url': 'http://purl.obolibrary.org/obo/HP_0030883', 'lbl': 'Femoroacetabular impingement', 'desc': 'label: Femoroacetabular impingement\ndefinition : Femoroacetabular impingement (FAI) results from one or more bony abnormalities that lead to abnormal contact between the acetabulum and the femoral head or neck. The femoral abnormality is proposed to cause compression and shear stresses in the region between the labrum and cartilage, anterosuperiorly. These stresses cause a separation between the labrum and cartilage as the labrum is pushed outwards and the cartilage is pushed centrally. This eventually leads to articular degeneration and eventually global hip osteoarthritis.\nsynonyms :Femoral acetabular impingement\n'}


{'id': 'HP_0030884', 'url': 'http://purl.obolibrary.org/obo/HP_0030884', 'lbl': 'Gastrojejunal tube feeding in infancy', 'desc': 'label: Gastrojejunal tube feeding in infancy\ndefinition : Feeding problem necessitating gastrojejunal tube feeding.\nsynonyms :Gastro-jejunal tube feeding in infancy\n'}


{'id': 'HP_0030885', 'url': 'http://purl.obolibrary.org/obo/HP_0030885', 'lbl': 'Recurrent parasitic infections', 'desc': 'label: Recurrent parasitic infections\ndefinition : Increased susceptibility to parasitic infections, as manifested by recurrent episodes of parasitic infection.\nsynonyms :\n'}


{'id': 'HP_0030886', 'url': 'http://purl.obolibrary.org/obo/HP_0030886', 'lbl': 'Abnormal lymphocyte apoptosis', 'desc': 'label: Abnormal lymphocyte apoptosis\ndefinition : A anomaly in the rate of programmed cell death (apoptosis) in lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0030887', 'url': 'http://purl.obolibrary.org/obo/HP_0030887', 'lbl': 'Increased lymphocyte apoptosis', 'desc': 'label: Increased lymphocyte apoptosis\ndefinition : A elevation in the rate of apoptosis in lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0030888', 'url': 'http://purl.obolibrary.org/obo/HP_0030888', 'lbl': 'C3 nephritic factor positivity', 'desc': 'label: C3 nephritic factor positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against C3 convertase (C3bBb).\nsynonyms :\n'}


{'id': 'HP_0030889', 'url': 'http://purl.obolibrary.org/obo/HP_0030889', 'lbl': 'Congenital shortened small intestine', 'desc': 'label: Congenital shortened small intestine\ndefinition : Substantially shortened length of the small intestine as a result of a developmental defect.\nsynonyms :Short bowel\n'}


{'id': 'HP_0030890', 'url': 'http://purl.obolibrary.org/obo/HP_0030890', 'lbl': 'Hyperintensity of cerebral white matter on MRI', 'desc': 'label: Hyperintensity of cerebral white matter on MRI\ndefinition : A brighter than expected signal on magnetic resonance imaging emanating from the cerebral white matter.\nsynonyms :White matter hyperintensity\n'}


{'id': 'HP_0030891', 'url': 'http://purl.obolibrary.org/obo/HP_0030891', 'lbl': 'Periventricular white matter hyperintensities', 'desc': 'label: Periventricular white matter hyperintensities\ndefinition : Areas of brighter than expected signal on magnetic resonance imaging emanating from the cerebral white matter that surrounds the cerebral ventricles.\nsynonyms :PVWMH\n'}


{'id': 'HP_0030892', 'url': 'http://purl.obolibrary.org/obo/HP_0030892', 'lbl': 'Deep cerebral white matter hyperintensities', 'desc': 'label: Deep cerebral white matter hyperintensities\ndefinition : Areas of brighter than expected signal on magnetic resonance imaging emanating from locations distant from the ventricular system.\nsynonyms :DWMH\n'}


{'id': 'HP_0030893', 'url': 'http://purl.obolibrary.org/obo/HP_0030893', 'lbl': 'Abnormal response to short acting pulmonary vasodilator', 'desc': 'label: Abnormal response to short acting pulmonary vasodilator\ndefinition : Pulmonary vasodilator testing is performed during right-heart catheterization and involves a short-acting vasoactive agent such as adenosine, epoprostenol, or inhaled nitric oxide. The current definition of a normal (positive) response is a drop in mean pulmonary artery pressure of at least 10 mm Hg (or 20 percent) to below 40 mm Hg.\nsynonyms :\n'}


{'id': 'HP_0030894', 'url': 'http://purl.obolibrary.org/obo/HP_0030894', 'lbl': 'Insufficient response to short acting pulmonary vasodilator', 'desc': 'label: Insufficient response to short acting pulmonary vasodilator\ndefinition : No fall in mean pulmonary arterial pressure (mPAP) falls by at least 10 mmHg to an absolute value less than 40 mmHg without a degradation in cardiac output (CO) in response to a short-acting vasoactive agent such as adenosine, epoprostenol, or inhaled nitric oxide.\nsynonyms :\n'}


{'id': 'HP_0030895', 'url': 'http://purl.obolibrary.org/obo/HP_0030895', 'lbl': 'Abnormal gastrointestinal motility', 'desc': 'label: Abnormal gastrointestinal motility\ndefinition : An anomaly of the muscular contractions that propel food though the gastrointestinal tract.\nsynonyms :Abnormal GI motility\n'}


{'id': 'HP_0030896', 'url': 'http://purl.obolibrary.org/obo/HP_0030896', 'lbl': 'Abnormal gastrointestinal transit time', 'desc': 'label: Abnormal gastrointestinal transit time\ndefinition : A deviation from the normal amount of time required for food to pass through the intestines.\nsynonyms :Abnormal GI transit time\n'}


{'id': 'HP_0030897', 'url': 'http://purl.obolibrary.org/obo/HP_0030897', 'lbl': 'Decreased intestinal transit time', 'desc': 'label: Decreased intestinal transit time\ndefinition : A reduction in the length of time required for food to pass through the intestines.\nsynonyms :\n'}


{'id': 'HP_0030898', 'url': 'http://purl.obolibrary.org/obo/HP_0030898', 'lbl': 'Pruritis on abdomen', 'desc': 'label: Pruritis on abdomen\ndefinition : Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the skin of the abdomen.\nsynonyms :\n'}


{'id': 'HP_0030899', 'url': 'http://purl.obolibrary.org/obo/HP_0030899', 'lbl': 'Pruritis on hand', 'desc': 'label: Pruritis on hand\ndefinition : Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the skin of the hand.\nsynonyms :\n'}


{'id': 'HP_0030900', 'url': 'http://purl.obolibrary.org/obo/HP_0030900', 'lbl': 'Pruritus on foot', 'desc': 'label: Pruritus on foot\ndefinition : Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the skin of the foot.\nsynonyms :Itchy feet; Itchy foot\n'}


{'id': 'HP_0030901', 'url': 'http://purl.obolibrary.org/obo/HP_0030901', 'lbl': 'Pruritis on breast', 'desc': 'label: Pruritis on breast\ndefinition : Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the skin of the breast.\nsynonyms :\n'}


{'id': 'HP_0030902', 'url': 'http://purl.obolibrary.org/obo/HP_0030902', 'lbl': 'Palmomental reflex', 'desc': 'label: Palmomental reflex\ndefinition : A type of primitive reflex characterized by an involuntary contraction of the mentalis muscle of the chin caused by stimulation of the thenar eminence of the palm.\nsynonyms :\n'}


{'id': 'HP_0030903', 'url': 'http://purl.obolibrary.org/obo/HP_0030903', 'lbl': 'Grasp reflex', 'desc': "label: Grasp reflex\ndefinition : A type of primitive reflex that can be elicated when the hand of the examiner is gently inserted into the palm of the patient's hand. The palmar surface is stroked or simply touched. The flexor surfaces of the fingers may be stimulated also by the examiner's fingers. The stimulus should be in a distal direction. With a positive response, the patient grasps the examiner's hand with variable strength and continues to grasp as the examiner's hand is moved. Ability to release the grip voluntarily depends on the activity of the reflex; some patients can do so readily, while others can even be lifted off the bed, since the grasp has such power [NCBI Books:NBK395].\nsynonyms :Palmar grasp reflex\n"}


{'id': 'HP_0030904', 'url': 'http://purl.obolibrary.org/obo/HP_0030904', 'lbl': 'Glabellar reflex', 'desc': "label: Glabellar reflex\ndefinition : A type of primitive reflex that is elicited by repetitive tapping on the forehead. Normal subjects usually blink in response to the first several taps, but if blinking persists, the response is abnormal and considered to be a sign of frontal release. Persistent blinking is also known as Myerson's sign.\nsynonyms :Myerson's sign\n"}


{'id': 'HP_0030905', 'url': 'http://purl.obolibrary.org/obo/HP_0030905', 'lbl': 'Snout reflex', 'desc': 'label: Snout reflex\ndefinition : A type of primitive reflex that is elicited by tapping the upper lip lightly. The contraction of the muscles causes the mouth to resemble a snout.\nsynonyms :\n'}


{'id': 'HP_0030906', 'url': 'http://purl.obolibrary.org/obo/HP_0030906', 'lbl': 'Suck reflex', 'desc': "label: Suck reflex\ndefinition : A type of primitive reflex that is elicited by lightly touching or tapping on the lips with an object such as a tongue blade, reflex hammer, or the examiner's finger. At times the reflex is obtained merely by approaching the lips with an object. A positive suck reflex consists of sucking movements by the lips when they are stroked or touched.\nsynonyms :Persistent nutritive suckle swallow\n"}


{'id': 'HP_0030907', 'url': 'http://purl.obolibrary.org/obo/HP_0030907', 'lbl': 'Thunderclap headache', 'desc': 'label: Thunderclap headache\ndefinition : Severe head pain with sudden onset, reaching its maximum intensity in less than one minute and lasting from one hour to ten days.\nsynonyms :\n'}


{'id': 'HP_0030908', 'url': 'http://purl.obolibrary.org/obo/HP_0030908', 'lbl': 'Liver kidney microsome type 1 antibody positivity', 'desc': 'label: Liver kidney microsome type 1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against P450 2D6, a cytochrome P450 mono-oxygenase. Anti-LKM-1 antibodies are considered to be a diagnostic marker of autoimmune hepatitis type 2 (AIH2).\nsynonyms :Anti-LKM-1 positive; Anti-LKM1 antibody positivity; Anti-liver kidney microsomal type 1 antibody positivity; Anti-type I liver-kidney microsomal antibody positivity\n'}


{'id': 'HP_0030909', 'url': 'http://purl.obolibrary.org/obo/HP_0030909', 'lbl': 'Anti-liver cytosolic antigen type 1 antibody positivity', 'desc': 'label: Anti-liver cytosolic antigen type 1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against a 60-kd peptide contained in the liver cytosolic fraction.\nsynonyms :Anti-liver cytosol antibody-1 positivity\n'}


{'id': 'HP_0030911', 'url': 'http://purl.obolibrary.org/obo/HP_0030911', 'lbl': 'Bifid clitoris', 'desc': 'label: Bifid clitoris\ndefinition : Two clitorides located side by side.\nsynonyms :\n'}


{'id': 'HP_0030912', 'url': 'http://purl.obolibrary.org/obo/HP_0030912', 'lbl': 'Duplicated clitoris', 'desc': 'label: Duplicated clitoris\ndefinition : Supernumerary clitoris.\nsynonyms :\n'}


{'id': 'HP_0030913', 'url': 'http://purl.obolibrary.org/obo/HP_0030913', 'lbl': 'Exaggerated rugosity of the labia majora', 'desc': 'label: Exaggerated rugosity of the labia majora\ndefinition : Marked rugae formation of the skin of the labia majora.\nsynonyms :Scrotum-like labia majora\n'}


{'id': 'HP_0030914', 'url': 'http://purl.obolibrary.org/obo/HP_0030914', 'lbl': 'Abnormal peristalsis', 'desc': 'label: Abnormal peristalsis\ndefinition : An anomaly of the wave-like muscle contractions of the digestive tract.\nsynonyms :\n'}


{'id': 'HP_0030915', 'url': 'http://purl.obolibrary.org/obo/HP_0030915', 'lbl': 'Cerebellar edema', 'desc': 'label: Cerebellar edema\ndefinition : Swelling from fluid accumulation (serous fluid infiltration into the interstitial space) in the cerebellum.\nsynonyms :Cerebellar oedema; Edema of the cerebellum; Oedema of the cerebellum\n'}


{'id': 'HP_0030917', 'url': 'http://purl.obolibrary.org/obo/HP_0030917', 'lbl': 'Low APGAR score', 'desc': 'label: Low APGAR score\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030918', 'url': 'http://purl.obolibrary.org/obo/HP_0030918', 'lbl': 'Low 1-minute APGAR score', 'desc': 'label: Low 1-minute APGAR score\ndefinition : \nsynonyms :Low one-minute APGAR score\n'}


{'id': 'HP_0030919', 'url': 'http://purl.obolibrary.org/obo/HP_0030919', 'lbl': 'Low 5-minute APGAR score', 'desc': 'label: Low 5-minute APGAR score\ndefinition : \nsynonyms :Low five-minute APGAR score\n'}


{'id': 'HP_0030920', 'url': 'http://purl.obolibrary.org/obo/HP_0030920', 'lbl': '5-minute APGAR score of 0', 'desc': 'label: 5-minute APGAR score of 0\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030921', 'url': 'http://purl.obolibrary.org/obo/HP_0030921', 'lbl': '5-minute APGAR score of 1', 'desc': 'label: 5-minute APGAR score of 1\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030922', 'url': 'http://purl.obolibrary.org/obo/HP_0030922', 'lbl': '5-minute APGAR score of 2', 'desc': 'label: 5-minute APGAR score of 2\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030923', 'url': 'http://purl.obolibrary.org/obo/HP_0030923', 'lbl': '5-minute APGAR score of 3', 'desc': 'label: 5-minute APGAR score of 3\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030924', 'url': 'http://purl.obolibrary.org/obo/HP_0030924', 'lbl': '5-minute APGAR score of 4', 'desc': 'label: 5-minute APGAR score of 4\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030925', 'url': 'http://purl.obolibrary.org/obo/HP_0030925', 'lbl': '5-minute APGAR score of 5', 'desc': 'label: 5-minute APGAR score of 5\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030926', 'url': 'http://purl.obolibrary.org/obo/HP_0030926', 'lbl': '5-minute APGAR score of 6', 'desc': 'label: 5-minute APGAR score of 6\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030927', 'url': 'http://purl.obolibrary.org/obo/HP_0030927', 'lbl': '1-minute APGAR score of 0', 'desc': 'label: 1-minute APGAR score of 0\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030928', 'url': 'http://purl.obolibrary.org/obo/HP_0030928', 'lbl': '1-minute APGAR score of 1', 'desc': 'label: 1-minute APGAR score of 1\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030929', 'url': 'http://purl.obolibrary.org/obo/HP_0030929', 'lbl': '1-minute APGAR score of 2', 'desc': 'label: 1-minute APGAR score of 2\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030930', 'url': 'http://purl.obolibrary.org/obo/HP_0030930', 'lbl': '1-minute APGAR score of 3', 'desc': 'label: 1-minute APGAR score of 3\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030931', 'url': 'http://purl.obolibrary.org/obo/HP_0030931', 'lbl': '1-minute APGAR score of 4', 'desc': 'label: 1-minute APGAR score of 4\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030932', 'url': 'http://purl.obolibrary.org/obo/HP_0030932', 'lbl': '1-minute APGAR score of 5', 'desc': 'label: 1-minute APGAR score of 5\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030933', 'url': 'http://purl.obolibrary.org/obo/HP_0030933', 'lbl': '1-minute APGAR score of 6', 'desc': 'label: 1-minute APGAR score of 6\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030934', 'url': 'http://purl.obolibrary.org/obo/HP_0030934', 'lbl': 'Oral erythroplakia', 'desc': 'label: Oral erythroplakia\ndefinition : A velvety red but not ulcerated lesion of the oral mucosa. The texture may be roughened or normal, and the lesion is neither raised nor depressed.\nsynonyms :Oral erythroplasia\n'}


{'id': 'HP_0030935', 'url': 'http://purl.obolibrary.org/obo/HP_0030935', 'lbl': 'Abnormality of intestinal smooth muscle morphology', 'desc': 'label: Abnormality of intestinal smooth muscle morphology\ndefinition : A structural anomaly of the nonstriated, involuntary muscle tissue of the intestine.\nsynonyms :\n'}


{'id': 'HP_0030936', 'url': 'http://purl.obolibrary.org/obo/HP_0030936', 'lbl': 'Abnormal layering of muscularis propria', 'desc': 'label: Abnormal layering of muscularis propria\ndefinition : Abnormal layering of the intestinal muscularis propria into three layers; (1) inner circular; (2) additional oblique; and (3) outer longitudinal layer.\nsynonyms :Muscularis propria malformation; Segmental additional circular muscle coat\n'}


{'id': 'HP_0030937', 'url': 'http://purl.obolibrary.org/obo/HP_0030937', 'lbl': 'Fibrotic muscularis propria', 'desc': 'label: Fibrotic muscularis propria\ndefinition : The presence of excessive fibrous connective tissue in the muscularis propria of the intestine. Fibrosis is a reparative or reactive process.\nsynonyms :\n'}


{'id': 'HP_0030938', 'url': 'http://purl.obolibrary.org/obo/HP_0030938', 'lbl': 'Enteric intraneuronal nuclear inclusion bodies', 'desc': 'label: Enteric intraneuronal nuclear inclusion bodies\ndefinition : Aggregates of stainable substances (proteins) in the nuclei of enteric neurons.\nsynonyms :\n'}


{'id': 'HP_0030939', 'url': 'http://purl.obolibrary.org/obo/HP_0030939', 'lbl': 'Palpebral thickening', 'desc': 'label: Palpebral thickening\ndefinition : An increased thickness of the eyelid not related to acute inflammation.\nsynonyms :Eyelid thickening; Thick eyelids; Thickened but nonswollen eyelids; Thickened eyelid\n'}


{'id': 'HP_0030943', 'url': 'http://purl.obolibrary.org/obo/HP_0030943', 'lbl': 'Vulvodynia', 'desc': 'label: Vulvodynia\ndefinition : Pain in the vulvar area\nsynonyms :Vulvar pain\n'}


{'id': 'HP_0030946', 'url': 'http://purl.obolibrary.org/obo/HP_0030946', 'lbl': 'Conjunctival papillae', 'desc': 'label: Conjunctival papillae\ndefinition : Raised tissue masses located on the palpebral conjunctiva with a central vessel. Papillae are created by a focal infiltration of inflammatory cells.\nsynonyms :Bumps under the upper eyelid; Tarsal papillae\n'}


{'id': 'HP_0030947', 'url': 'http://purl.obolibrary.org/obo/HP_0030947', 'lbl': 'Conjunctival follicles', 'desc': 'label: Conjunctival follicles\ndefinition : Small, dome-shaped nodules without a prominent central vessel located on the conjunctiva. The lymphoid follicles are located in the subendothelial region of the conjunctiva. They consist of a germinal center that contains immature, proliferating lymphocytes, as well as a corona that contains mature lymphocytes and plasma cells.\nsynonyms :\n'}


{'id': 'HP_0030948', 'url': 'http://purl.obolibrary.org/obo/HP_0030948', 'lbl': 'Elevated gamma-glutamyltransferase level', 'desc': 'label: Elevated gamma-glutamyltransferase level\ndefinition : Increased level of the enzyme gamma-glutamyltransferase (GGT). GGT is mainly present in kidney, liver, and pancreatic cells, but small amounts are present in other tissues.\nsynonyms :Elevated serum GGT\n'}


{'id': 'HP_0030949', 'url': 'http://purl.obolibrary.org/obo/HP_0030949', 'lbl': 'Glomerular deposits', 'desc': 'label: Glomerular deposits\ndefinition : An abnormal accumulation of protein in the glomerulus.\nsynonyms :\n'}


{'id': 'HP_0030950', 'url': 'http://purl.obolibrary.org/obo/HP_0030950', 'lbl': 'Pulmonary venous hypertension', 'desc': 'label: Pulmonary venous hypertension\ndefinition : An abnormal increase in pressure in the pulmonary veins, usually as a result of left atrial hypertension.\nsynonyms :\n'}


{'id': 'HP_0030951', 'url': 'http://purl.obolibrary.org/obo/HP_0030951', 'lbl': 'Skeletal muscle fibrosis', 'desc': 'label: Skeletal muscle fibrosis\ndefinition : Excessive formation of fibrous bands of scar tissue in between muscle fibers.\nsynonyms :Muscle biopsy: fibrosis\n'}


{'id': 'HP_0030952', 'url': 'http://purl.obolibrary.org/obo/HP_0030952', 'lbl': 'Birdshot retinochoroidopathy', 'desc': 'label: Birdshot retinochoroidopathy\ndefinition : Multiple cream-yellow colored hypopigmented lesions typically located at the level of the choroid or retinal pigment epithelium; ovoid, cream-colored with indistinct borders. They are between 50 and 1,500 micrometers in size with a characteristic nasal, radial distribution in the postequatorial fundus.\nsynonyms :Birdshot choroidal lesions; Birdshot laesions; Birdshot lesions\n'}


{'id': 'HP_0030953', 'url': 'http://purl.obolibrary.org/obo/HP_0030953', 'lbl': 'Conjunctival hyperemia', 'desc': 'label: Conjunctival hyperemia\ndefinition : Dilatation of the blood vessels of the conjunctiva leading to a red appearance of the sclera.\nsynonyms :Conjunctival hyperaemia; Conjunctival injection; Conjunctival vascular congestion\n'}


{'id': 'HP_0030955', 'url': 'http://purl.obolibrary.org/obo/HP_0030955', 'lbl': 'Alcoholism', 'desc': 'label: Alcoholism\ndefinition : An addictive behavior defined as drinking excessive amounts of alcohol over a long period of time, having difficulty reducing the amount of alcohol consumed, strongly desiring alcohol and experiencing withdrawal symptoms when not drinking alcohol.\nsynonyms :\n'}


{'id': 'HP_0030956', 'url': 'http://purl.obolibrary.org/obo/HP_0030956', 'lbl': 'Abnormality of cardiovascular system electrophysiology', 'desc': 'label: Abnormality of cardiovascular system electrophysiology\ndefinition : An anomaly of the electrical conduction physiology of the heart.\nsynonyms :\n'}


{'id': 'HP_0030957', 'url': 'http://purl.obolibrary.org/obo/HP_0030957', 'lbl': 'Ventricular septal aneurysm', 'desc': 'label: Ventricular septal aneurysm\ndefinition : A bowing (bulging to one side) of the interventricular septum of more than 15 mm on either side in adults and 5 mm in children during normal cardiac motion.\nsynonyms :Ventricular septal dilatation\n'}


{'id': 'HP_0030958', 'url': 'http://purl.obolibrary.org/obo/HP_0030958', 'lbl': 'Membranous ventricular septal aneurysm', 'desc': 'label: Membranous ventricular septal aneurysm\ndefinition : Bowing (bulging out) of the membranous part of the interventricular septum of more than 10-15 mm into the cavity of an adjacent ventricle (usually into the right ventricle).\nsynonyms :Interventricular septum membranous part aneurysm; Aneurysm of the membranous ventricular septum\n'}


{'id': 'HP_0030959', 'url': 'http://purl.obolibrary.org/obo/HP_0030959', 'lbl': 'Muscular ventricular septal aneurysm', 'desc': 'label: Muscular ventricular septal aneurysm\ndefinition : Bowing (bulging out) of the muscular part of the interventricular septum of more than 10-15 mm into the cavity of an adjacent ventricle (usually into the right ventricle).\nsynonyms :Aneurysm of the muscular ventricular septum\n'}


{'id': 'HP_0030960', 'url': 'http://purl.obolibrary.org/obo/HP_0030960', 'lbl': 'obsolete Abnormal pupillary morphology', 'desc': 'label: obsolete Abnormal pupillary morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030961', 'url': 'http://purl.obolibrary.org/obo/HP_0030961', 'lbl': 'Microspherophakia', 'desc': 'label: Microspherophakia\ndefinition : Lens of the eye is smaller than normal and spherically shaped.\nsynonyms :\n'}


{'id': 'HP_0030962', 'url': 'http://purl.obolibrary.org/obo/HP_0030962', 'lbl': 'Abnormal morphology of the great vessels', 'desc': 'label: Abnormal morphology of the great vessels\ndefinition : A structural anomaly affecting a blood vessel involved in the circulation of the heart, i.e., the superior or inferior vena cava, the pulmonary arteries, the pulmonary veins, and the aorta.\nsynonyms :\n'}


{'id': 'HP_0030963', 'url': 'http://purl.obolibrary.org/obo/HP_0030963', 'lbl': 'obsolete Abnormal aortic morphology', 'desc': 'label: obsolete Abnormal aortic morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030964', 'url': 'http://purl.obolibrary.org/obo/HP_0030964', 'lbl': 'Abnormal aortic physiology', 'desc': 'label: Abnormal aortic physiology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030965', 'url': 'http://purl.obolibrary.org/obo/HP_0030965', 'lbl': 'Aortic stiffness', 'desc': 'label: Aortic stiffness\ndefinition : The elastic properties of the aorta allow the aorta to store half of the cardiac ejected blood volume per beat, whereby aortic recoil during diastole pushes the remaining stored volume forward into the peripheral circulation, a phenomenon known as the Windkessel function. Aortic stiffness occurs as the elastic fibers within the arterial wall become disrupted due to mechanical stress (with age or due to other factors). Aortic stiffness refers to a reduction in the elasticity of the aorta, which is associated with an elevated pulse pressure, increased wave reflection, and often hypertension.\nsynonyms :Increased aortic stiffness\n'}


{'id': 'HP_0030966', 'url': 'http://purl.obolibrary.org/obo/HP_0030966', 'lbl': 'Abnormal pulmonary artery morphology', 'desc': 'label: Abnormal pulmonary artery morphology\ndefinition : An abnormality of the structure of the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0030967', 'url': 'http://purl.obolibrary.org/obo/HP_0030967', 'lbl': 'Abnormal pulmonary artery physiology', 'desc': 'label: Abnormal pulmonary artery physiology\ndefinition : An abnormality of the function of the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0030968', 'url': 'http://purl.obolibrary.org/obo/HP_0030968', 'lbl': 'Abnormal pulmonary vein morphology', 'desc': 'label: Abnormal pulmonary vein morphology\ndefinition : An abnormality of the structure of the pulmonary veins.\nsynonyms :\n'}


{'id': 'HP_0030969', 'url': 'http://purl.obolibrary.org/obo/HP_0030969', 'lbl': 'Abnormal pulmonary vein physiology', 'desc': 'label: Abnormal pulmonary vein physiology\ndefinition : An abnormality of the function of the pulmonary veins.\nsynonyms :\n'}


{'id': 'HP_0030970', 'url': 'http://purl.obolibrary.org/obo/HP_0030970', 'lbl': 'Abnormal vena cava physiology', 'desc': 'label: Abnormal vena cava physiology\ndefinition : An abnormality of the function of the veins that return deoxygenated blood from the body into the heart, i.e., the superior vena cava and the inferior vena cava.\nsynonyms :\n'}


{'id': 'HP_0030971', 'url': 'http://purl.obolibrary.org/obo/HP_0030971', 'lbl': 'obsolete Abnormal vena cava morphology', 'desc': 'label: obsolete Abnormal vena cava morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0030972', 'url': 'http://purl.obolibrary.org/obo/HP_0030972', 'lbl': 'Abnormal systemic blood pressure', 'desc': 'label: Abnormal systemic blood pressure\ndefinition : A chronic deviation from normal pressure in the systemic arterial system.\nsynonyms :Abnormal systemic BP\n'}


{'id': 'HP_0030973', 'url': 'http://purl.obolibrary.org/obo/HP_0030973', 'lbl': 'Postexertional symptom exacerbation', 'desc': 'label: Postexertional symptom exacerbation\ndefinition : Post-exertional symptom exacerbation (PESE), also referred to as post-exertional malaise (PEM), is defined as the worsening of symptoms that can follow minimal cognitive, physical, emotional, or social activity, or activity that could previously be tolerated. Symptoms typically worsen 12 to 72 hours after activity and can last for days or even weeks, sometimes leading to a relapse.\nsynonyms :Exercise-induced malaise; Postexertional malaise\n'}


{'id': 'HP_0030974', 'url': 'http://purl.obolibrary.org/obo/HP_0030974', 'lbl': 'Cryptozoospermia', 'desc': 'label: Cryptozoospermia\ndefinition : A type of low sperm count where ejaculated semen contains less than 100,000 spermatozoa per ml. With cryptozoospermia, the sperm count may fluctuate and a zero sperm count in the ejaculate may be initially measured. If sperm are observed in a second semen sample following centrifugation, the diagnosis of cryptozoospermia can be made (and azoospermia can be ruled out).\nsynonyms :Cryptospermia\n'}


{'id': 'HP_0030975', 'url': 'http://purl.obolibrary.org/obo/HP_0030975', 'lbl': 'Pontine tegmental cap', 'desc': 'label: Pontine tegmental cap\ndefinition : An abnormal curved or vaulted (capped) structure covering the middle third of the dorsal pontine tegmentum and projecting into the fourth ventricle.\nsynonyms :Vaulted pontine tegmentum\n'}


{'id': 'HP_0030976', 'url': 'http://purl.obolibrary.org/obo/HP_0030976', 'lbl': 'Abnormal factor VIII activity', 'desc': 'label: Abnormal factor VIII activity\ndefinition : A deviation from the normal activity of coagulation factor VIII. Factor VIII (fVIII) is a cofactor in the intrinsic clotting cascade that is activated to fVIIIa in the presence of minute quantities of thrombin. fVIIIa acts as a receptor, for factors IXa and X.\nsynonyms :\n'}


{'id': 'HP_0030977', 'url': 'http://purl.obolibrary.org/obo/HP_0030977', 'lbl': 'Increased factor VIII activity', 'desc': 'label: Increased factor VIII activity\ndefinition : Increased activity of the coagulation factor VIII. Factor VIII (fVIII) is a cofactor in the intrinsic clotting cascade that is activated to fVIIIa in the presence of minute quantities of thrombin. fVIIIa acts as a receptor, for factors IXa and X.\nsynonyms :Elevated factor VIII level\n'}


{'id': 'HP_0030978', 'url': 'http://purl.obolibrary.org/obo/HP_0030978', 'lbl': 'Decreased CSF/serum albumin ratio', 'desc': 'label: Decreased CSF/serum albumin ratio\ndefinition : A reduction below normal limits of the ratio of the cerebrospinal fluid (CSF) albumin concentration to serum albumin concentration.\nsynonyms :\n'}


{'id': 'HP_0030979', 'url': 'http://purl.obolibrary.org/obo/HP_0030979', 'lbl': 'Dilatation of large choroidal vessels', 'desc': 'label: Dilatation of large choroidal vessels\ndefinition : Enlargement of the large blood vessels in the choroid.\nsynonyms :Dilated choroidal vessels\n'}


{'id': 'HP_0030980', 'url': 'http://purl.obolibrary.org/obo/HP_0030980', 'lbl': 'Reduced brain glutamine level by MRS', 'desc': 'label: Reduced brain glutamine level by MRS\ndefinition : An decrease in the level of glutamine in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :\n'}


{'id': 'HP_0030981', 'url': 'http://purl.obolibrary.org/obo/HP_0030981', 'lbl': 'Abnormal CSF/serum albumin ratio', 'desc': 'label: Abnormal CSF/serum albumin ratio\ndefinition : A deviation from the normal range of the ratio of the albumin concentration in the cerebrospinal fluid (CSF) to the concentration in serum (which may be defined as 3.2-9.0). This is an index of blood-brain barrier (BBB) integrity, adjusted for the serum albumin concentration, and an increased ratio is taken as a sign of a loss of integrity of the BBB with leakage of albumin into the CSF.\nsynonyms :\n'}


{'id': 'HP_0030983', 'url': 'http://purl.obolibrary.org/obo/HP_0030983', 'lbl': 'Ovarian thecoma', 'desc': 'label: Ovarian thecoma\ndefinition : A sex cord-stromal tumor of the ovary. Thecomas range from small tumors to large solid or solid-cystic masses of up to 15 cm. They are unilateral in over 90 percent of cases and are rarely malignant. Thecomas are stromal tumors made up of cells that resemble theca cells, lutein cells and fibroblasts. They are traditionally classified within the sex cord-stromal tumor category of ovarian tumor types.\nsynonyms :\n'}


{'id': 'HP_0030984', 'url': 'http://purl.obolibrary.org/obo/HP_0030984', 'lbl': 'Abnormal serum bile acid concentration', 'desc': 'label: Abnormal serum bile acid concentration\ndefinition : A deviation from the normal concentration of serum bile acid concentration.\nsynonyms :\n'}


{'id': 'HP_0030985', 'url': 'http://purl.obolibrary.org/obo/HP_0030985', 'lbl': 'Decreased serum bile acid concentration', 'desc': 'label: Decreased serum bile acid concentration\ndefinition : A reduction in the concentration of bile acid in the blood.\nsynonyms :\n'}


{'id': 'HP_0030986', 'url': 'http://purl.obolibrary.org/obo/HP_0030986', 'lbl': 'Biliary epithelial hyperplasia', 'desc': 'label: Biliary epithelial hyperplasia\ndefinition : Hyperplasia of lining epithelia of the septal and large bile ducts manifesting as micropapillary projections or as a stratification of the epithelium with or without dilatation of the duct lumen.\nsynonyms :\n'}


{'id': 'HP_0030987', 'url': 'http://purl.obolibrary.org/obo/HP_0030987', 'lbl': 'Suppurative cholangitis', 'desc': 'label: Suppurative cholangitis\ndefinition : Cholangitis characterized by the presence of numerous polymorphonuclear cells around and within the wall as well as within the lumen of the ducts. This may involve ducts of any size and is occasionally associated with abscess formation (cholangitic abscess).\nsynonyms :\n'}


{'id': 'HP_0030988', 'url': 'http://purl.obolibrary.org/obo/HP_0030988', 'lbl': 'Granulomatous cholangitis', 'desc': 'label: Granulomatous cholangitis\ndefinition : Cholangitis characterized by the accumulation of granulomas. Granulomas are aggregates of modified macrophages (epithelioid cells) and other inflammatory cells that accumulate after chronic exposure to antigens. The underlying trigger may be exposure to noxious agents that cannot be biochemically degraded or to immune dysfunction. The ultimate result is a release of a variety cytokines that stimulate mononuclear cells that fuse to form multinucleated giant cells with a surrounding rim of lymphocytes and fibroblasts.\nsynonyms :\n'}


{'id': 'HP_0030989', 'url': 'http://purl.obolibrary.org/obo/HP_0030989', 'lbl': 'Lymphoid cholangitis', 'desc': 'label: Lymphoid cholangitis\ndefinition : Cholangitis characterized by a close association between duct branches, usually interlobular bile ducts, and lymphocytic aggregates, which may show a follicular arrangement.\nsynonyms :\n'}


{'id': 'HP_0030990', 'url': 'http://purl.obolibrary.org/obo/HP_0030990', 'lbl': 'Pleomorphic cholangitis', 'desc': 'label: Pleomorphic cholangitis\ndefinition : Cholangitis associated with mixed inflammatory infiltrates and the presence of fibrosis or sclerosis of the biliary tree.\nsynonyms :\n'}


{'id': 'HP_0030991', 'url': 'http://purl.obolibrary.org/obo/HP_0030991', 'lbl': 'Sclerosing cholangitis', 'desc': 'label: Sclerosing cholangitis\ndefinition : Cholangitis associated with evident ductal fibrosis that develops as a consequence of long-standing bile duct inflammatory, obstruction, or ischemic injury; it can be obliterative or nonobliterative.\nsynonyms :Fibrous cholangitis\n'}


{'id': 'HP_0030992', 'url': 'http://purl.obolibrary.org/obo/HP_0030992', 'lbl': 'Abnormal pancreatic duct morphology', 'desc': 'label: Abnormal pancreatic duct morphology\ndefinition : Any structural anomaly of the pancreatic duct, which is the tubular structure that collects exocrine pancreatic secretions and transports them to the duodenum.\nsynonyms :\n'}


{'id': 'HP_0030993', 'url': 'http://purl.obolibrary.org/obo/HP_0030993', 'lbl': 'Duplication of pancreatic duct', 'desc': 'label: Duplication of pancreatic duct\ndefinition : A congenital anomaly characterized by the presence of two separate pancreatic ducts.\nsynonyms :Duplicated pancreatic duct\n'}


{'id': 'HP_0030994', 'url': 'http://purl.obolibrary.org/obo/HP_0030994', 'lbl': 'Pancreas divisum', 'desc': 'label: Pancreas divisum\ndefinition : A congenital anomaly of the pancreas that results from failed fusion of the dorsal and ventral ducts during embyological development. Three variants have been described: type 1 or classical divisum in which there is total failure of fusion; type 2 in which dorsal drainage is dominant in the absence of the duct of Wirsung; and type 3 or incomplete divisum where a small communicating branch is present.\nsynonyms :\n'}


{'id': 'HP_0030995', 'url': 'http://purl.obolibrary.org/obo/HP_0030995', 'lbl': 'Peritoneal effusion', 'desc': 'label: Peritoneal effusion\ndefinition : An increase in the amount of fluid present in the peritoneal cavity (between the layers of the peritoneum that lines the abdomen).\nsynonyms :\n'}


{'id': 'HP_0030996', 'url': 'http://purl.obolibrary.org/obo/HP_0030996', 'lbl': 'Megaduodenum', 'desc': 'label: Megaduodenum\ndefinition : Dilation and elongation of the duodenum with hypertrophy of all layers of the duodenum.\nsynonyms :\n'}


{'id': 'HP_0030997', 'url': 'http://purl.obolibrary.org/obo/HP_0030997', 'lbl': 'Atretic vas deferens', 'desc': 'label: Atretic vas deferens\ndefinition : Abnormal closure or blockage of the vas deferens.\nsynonyms :Atresia of the vas deferens; Vas deferens atresia\n'}


{'id': 'HP_0030998', 'url': 'http://purl.obolibrary.org/obo/HP_0030998', 'lbl': 'Cerebrospinal fluid rhinorrhoea', 'desc': 'label: Cerebrospinal fluid rhinorrhoea\ndefinition : Drainage of cerebrospinal fluid through the nose. This can occur when there is a fistula between the dura and the skull base and discharge of cerebrospinal fluid (CSF) from the nose.\nsynonyms :CSF rhinorrhoea\n'}


{'id': 'HP_0030999', 'url': 'http://purl.obolibrary.org/obo/HP_0030999', 'lbl': 'Abnormal vestibular saccule morphology', 'desc': 'label: Abnormal vestibular saccule morphology\ndefinition : Any structural anomaly of the saccule of the vestibule. The saccule is the otolith organ that senses motions in the sagittal plane (i.e., up-down movement).\nsynonyms :\n'}


{'id': 'HP_0031000', 'url': 'http://purl.obolibrary.org/obo/HP_0031000', 'lbl': 'Vestibular saccular degeneration', 'desc': 'label: Vestibular saccular degeneration\ndefinition : Deterioration or loss of the tissues of the saccule of the vestibule.\nsynonyms :\n'}


{'id': 'HP_0031001', 'url': 'http://purl.obolibrary.org/obo/HP_0031001', 'lbl': 'Minifascicle formation', 'desc': 'label: Minifascicle formation\ndefinition : A nerve fascicle or fasciculus is a small bundle of axons, enclosed by the perineurium. A minifascule refers to a group of thinly myelinated and unmyelinated axons surrounded by a delicate perineurium, and with a smaller diameter than a normal nerve fascicle.\nsynonyms :\n'}


{'id': 'HP_0031002', 'url': 'http://purl.obolibrary.org/obo/HP_0031002', 'lbl': 'Neuritis', 'desc': 'label: Neuritis\ndefinition : Inflammation of a nerve.\nsynonyms :\n'}


{'id': 'HP_0031003', 'url': 'http://purl.obolibrary.org/obo/HP_0031003', 'lbl': 'Polyneuritis', 'desc': 'label: Polyneuritis\ndefinition : Simulataneous inflammation of multiple nerves.\nsynonyms :Multiple neuritis\n'}


{'id': 'HP_0031004', 'url': 'http://purl.obolibrary.org/obo/HP_0031004', 'lbl': 'Hemiareflexia', 'desc': 'label: Hemiareflexia\ndefinition : Areflexia that is limited to one side of the body.\nsynonyms :\n'}


{'id': 'HP_0031005', 'url': 'http://purl.obolibrary.org/obo/HP_0031005', 'lbl': 'obsolete Hyperalgesia', 'desc': 'label: obsolete Hyperalgesia\ndefinition : \nsynonyms :\n'}