{'id': 'HP_0012664', 'url': 'http://purl.obolibrary.org/obo/HP_0012664', 'lbl': 'Reduced left ventricular ejection fraction', 'desc': 'label: Reduced left ventricular ejection fraction\ndefinition : A diminution of the volumetric fraction of blood pumped out of the ventricle with each cardiac cycle.\nsynonyms :Reduced ejection fraction\n'}


{'id': 'HP_0012665', 'url': 'http://purl.obolibrary.org/obo/HP_0012665', 'lbl': 'Moderately reduced left ventricular ejection fraction', 'desc': 'label: Moderately reduced left ventricular ejection fraction\ndefinition : A medium reduction in the fraction of blood pumped from the left ventricle with each cardiac cycle, defined as a left ventricular ejection fraction of 30-39 percent.\nsynonyms :Moderately reduced ejection fraction\n'}


{'id': 'HP_0012666', 'url': 'http://purl.obolibrary.org/obo/HP_0012666', 'lbl': 'Severely reduced left ventricular ejection fraction', 'desc': 'label: Severely reduced left ventricular ejection fraction\ndefinition : A large reduction in the fraction of blood pumped from the left ventricle with each cardiac cycle. The normal range in adults is at over 50 percent, and a severe reduction is defined as less than 30 percent.\nsynonyms :Severely reduced ejection fraction\n'}


{'id': 'HP_0012667', 'url': 'http://purl.obolibrary.org/obo/HP_0012667', 'lbl': 'Regional left ventricular wall motion abnormality', 'desc': 'label: Regional left ventricular wall motion abnormality\ndefinition : An abnormal motion of a segment of the left ventricle during the cardiac cycle.\nsynonyms :\n'}


{'id': 'HP_0012668', 'url': 'http://purl.obolibrary.org/obo/HP_0012668', 'lbl': 'Vasovagal syncope', 'desc': 'label: Vasovagal syncope\ndefinition : \nsynonyms :Neurocardiogenic syncope; Reflex syncope; Situational syncope\n'}


{'id': 'HP_0012669', 'url': 'http://purl.obolibrary.org/obo/HP_0012669', 'lbl': 'Carotid sinus syncope', 'desc': 'label: Carotid sinus syncope\ndefinition : An exaggerated response to carotid sinus baroreceptor stimulation resulting in syncope from transient diminished cerebral perfusion.\nsynonyms :\n'}


{'id': 'HP_0012670', 'url': 'http://purl.obolibrary.org/obo/HP_0012670', 'lbl': 'Orthostatic syncope', 'desc': 'label: Orthostatic syncope\ndefinition : Syncope following a quick change in position from lying down to standing.\nsynonyms :\n'}


{'id': 'HP_0012671', 'url': 'http://purl.obolibrary.org/obo/HP_0012671', 'lbl': 'Abulia', 'desc': 'label: Abulia\ndefinition : Poverty of behavior and speech output, lack of initiative, loss of emotional responses, psychomotor slowing, and prolonged speech latency.\nsynonyms :Aboulia\n'}


{'id': 'HP_0012672', 'url': 'http://purl.obolibrary.org/obo/HP_0012672', 'lbl': 'Akinetic mutism', 'desc': 'label: Akinetic mutism\ndefinition : Akinetic mutism is essentially characterized by a total absence of spontaneous behavior and speech occurring in the presence of preserved visual tracking.\nsynonyms :\n'}


{'id': 'HP_0012673', 'url': 'http://purl.obolibrary.org/obo/HP_0012673', 'lbl': 'Aplasia of the upper vagina', 'desc': 'label: Aplasia of the upper vagina\ndefinition : A failure to develop of the upper vagina.\nsynonyms :Absent upper vagina\n'}


{'id': 'HP_0012674', 'url': 'http://purl.obolibrary.org/obo/HP_0012674', 'lbl': 'Aplasia of the lower vagina', 'desc': 'label: Aplasia of the lower vagina\ndefinition : A failure to develop of the lower part of the vagina.\nsynonyms :Absent lower vagina; Agenesis of the lower vagina\n'}


{'id': 'HP_0012675', 'url': 'http://purl.obolibrary.org/obo/HP_0012675', 'lbl': 'Iron accumulation in brain', 'desc': 'label: Iron accumulation in brain\ndefinition : An abnormal build up of iron (Fe) in brain tissue.\nsynonyms :Brain iron deposition; Iron accumulation in brain\n'}


{'id': 'HP_0012676', 'url': 'http://purl.obolibrary.org/obo/HP_0012676', 'lbl': 'Copper accumulation in brain', 'desc': 'label: Copper accumulation in brain\ndefinition : An anomalous build up of copper (Cu) in the brain.\nsynonyms :Brain copper accumulation; Copper accumulation in brain\n'}


{'id': 'HP_0012677', 'url': 'http://purl.obolibrary.org/obo/HP_0012677', 'lbl': 'obsolete Iron accumulation in globus pallidus', 'desc': 'label: obsolete Iron accumulation in globus pallidus\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012678', 'url': 'http://purl.obolibrary.org/obo/HP_0012678', 'lbl': 'Iron accumulation in substantia nigra', 'desc': 'label: Iron accumulation in substantia nigra\ndefinition : An anomalous build up of iron (Fe) in the substantia nigra.\nsynonyms :\n'}


{'id': 'HP_0012679', 'url': 'http://purl.obolibrary.org/obo/HP_0012679', 'lbl': 'Widened interpedicular distance', 'desc': 'label: Widened interpedicular distance\ndefinition : An increase in the distance between vertebral pedicles, which are the two short, thick processes, which project backward, one on either side, from the upper part of the vertebral body, at the junction of its posterior and lateral surfaces.\nsynonyms :\n'}


{'id': 'HP_0012680', 'url': 'http://purl.obolibrary.org/obo/HP_0012680', 'lbl': 'Abnormality of the pineal gland', 'desc': 'label: Abnormality of the pineal gland\ndefinition : An anomaly of the pineal gland,a small endocrine gland in the brain that produces melatonin.\nsynonyms :\n'}


{'id': 'HP_0012681', 'url': 'http://purl.obolibrary.org/obo/HP_0012681', 'lbl': 'Abnormal pineal morphology', 'desc': 'label: Abnormal pineal morphology\ndefinition : A structural abnormality of the pineal gland.\nsynonyms :Abnormality of pineal morphology\n'}


{'id': 'HP_0012682', 'url': 'http://purl.obolibrary.org/obo/HP_0012682', 'lbl': 'Pineal gland calcification', 'desc': 'label: Pineal gland calcification\ndefinition : Accumulation of calcium salts in the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012683', 'url': 'http://purl.obolibrary.org/obo/HP_0012683', 'lbl': 'Pineal cyst', 'desc': 'label: Pineal cyst\ndefinition : A glial uniloculated or multiloculated fluid-filled sac that either reside within or completely replace the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012684', 'url': 'http://purl.obolibrary.org/obo/HP_0012684', 'lbl': 'Abnormal pineal volume', 'desc': 'label: Abnormal pineal volume\ndefinition : An abnormal increase or decrease in the quantity of three-dimensional space taken up by the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012685', 'url': 'http://purl.obolibrary.org/obo/HP_0012685', 'lbl': 'Decreased pineal volume', 'desc': 'label: Decreased pineal volume\ndefinition : An abnormal reduction in the quantity of three-dimensional space taken up by the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012686', 'url': 'http://purl.obolibrary.org/obo/HP_0012686', 'lbl': 'Increased pineal volume', 'desc': 'label: Increased pineal volume\ndefinition : An abnormal elevation in the quantity of three-dimensional space taken up by the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012687', 'url': 'http://purl.obolibrary.org/obo/HP_0012687', 'lbl': 'Agenesis of pineal gland', 'desc': 'label: Agenesis of pineal gland\ndefinition : Failure to develop of the pineal gland, defined clinically as the absence of the pineal gland with no indication of the pineal gland even having been present.\nsynonyms :\n'}


{'id': 'HP_0012688', 'url': 'http://purl.obolibrary.org/obo/HP_0012688', 'lbl': 'Abnormality of pineal physiology', 'desc': 'label: Abnormality of pineal physiology\ndefinition : A functional abnormality of the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012689', 'url': 'http://purl.obolibrary.org/obo/HP_0012689', 'lbl': 'Abnormal pineal melatonin secretion', 'desc': 'label: Abnormal pineal melatonin secretion\ndefinition : An anomaly in the amount or timing of melatonin secretion by the pineal gland. Note that melatonin is also synthesized by multiple tissues outside of the pineal gland.\nsynonyms :\n'}


{'id': 'HP_0012690', 'url': 'http://purl.obolibrary.org/obo/HP_0012690', 'lbl': 'T2 hypointense thalamus', 'desc': 'label: T2 hypointense thalamus\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the thalamus. This term refers to a diffuse hypointensity affecting the entire thalamus.\nsynonyms :\n'}


{'id': 'HP_0012691', 'url': 'http://purl.obolibrary.org/obo/HP_0012691', 'lbl': 'Focal T2 hypointense thalamic lesion', 'desc': 'label: Focal T2 hypointense thalamic lesion\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the thalamus. This term refers to a localized hypointensity affecting a particular region of the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012692', 'url': 'http://purl.obolibrary.org/obo/HP_0012692', 'lbl': 'Focal T2 hyperintense thalamic lesion', 'desc': 'label: Focal T2 hyperintense thalamic lesion\ndefinition : A lighter than expected T2 signal on magnetic resonance imaging (MRI) of the thalamus. This term refers to a localized hyperintensity affecting a particular region of the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012693', 'url': 'http://purl.obolibrary.org/obo/HP_0012693', 'lbl': 'Abnormal thalamic size', 'desc': 'label: Abnormal thalamic size\ndefinition : Deviation from the normal range of size of the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012694', 'url': 'http://purl.obolibrary.org/obo/HP_0012694', 'lbl': 'Enlarged thalamic volume', 'desc': 'label: Enlarged thalamic volume\ndefinition : An increase in the quantity of space occupied by the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012695', 'url': 'http://purl.obolibrary.org/obo/HP_0012695', 'lbl': 'Decreased thalamic volume', 'desc': 'label: Decreased thalamic volume\ndefinition : A reduction in the quantity of space occupied by the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012696', 'url': 'http://purl.obolibrary.org/obo/HP_0012696', 'lbl': 'Abnormal thalamic MRI signal intensity', 'desc': 'label: Abnormal thalamic MRI signal intensity\ndefinition : A deviation from normal signal on magnetic resonance imaging (MRI) of the thalamus.\nsynonyms :\n'}


{'id': 'HP_0012697', 'url': 'http://purl.obolibrary.org/obo/HP_0012697', 'lbl': 'Small basal ganglia', 'desc': 'label: Small basal ganglia\ndefinition : Decreased size of the basal ganglia.\nsynonyms :\n'}


{'id': 'HP_0012698', 'url': 'http://purl.obolibrary.org/obo/HP_0012698', 'lbl': 'Cerebellar gliosis', 'desc': 'label: Cerebellar gliosis\ndefinition : Focal proliferation of glial cells in the cerebellum.\nsynonyms :\n'}


{'id': 'HP_0012699', 'url': 'http://purl.obolibrary.org/obo/HP_0012699', 'lbl': 'Anomaly of lower limb diaphyses', 'desc': 'label: Anomaly of lower limb diaphyses\ndefinition : A structural abnormality of a diaphysis of the leg.\nsynonyms :Anomaly of shaft of long bone of lower limb\n'}


{'id': 'HP_0012700', 'url': 'http://purl.obolibrary.org/obo/HP_0012700', 'lbl': 'Abnormal large intestine physiology', 'desc': 'label: Abnormal large intestine physiology\ndefinition : A functional anomaly of the large intestine.\nsynonyms :\n'}


{'id': 'HP_0012701', 'url': 'http://purl.obolibrary.org/obo/HP_0012701', 'lbl': 'Bowel urgency', 'desc': 'label: Bowel urgency\ndefinition : A sudden, irresistible need to have a bowel movement.\nsynonyms :Faecal urgency; Fecal urgency\n'}


{'id': 'HP_0012702', 'url': 'http://purl.obolibrary.org/obo/HP_0012702', 'lbl': 'Tenesmus', 'desc': 'label: Tenesmus\ndefinition : A repeated, painful urge to defecate without excreting stool.\nsynonyms :\n'}


{'id': 'HP_0012703', 'url': 'http://purl.obolibrary.org/obo/HP_0012703', 'lbl': 'Abnormal subarachnoid space morphology', 'desc': 'label: Abnormal subarachnoid space morphology\ndefinition : Abnormality in the space in the meninges beneath the arachnoid membrane and above the pia mater that contains the cerebrospinal fluid.\nsynonyms :Abnormality of the subarachnoid space\n'}


{'id': 'HP_0012704', 'url': 'http://purl.obolibrary.org/obo/HP_0012704', 'lbl': 'Widened subarachnoid space', 'desc': 'label: Widened subarachnoid space\ndefinition : An increase in size of the anatomic space between the arachnoid membrane and pia mater.\nsynonyms :Enlarged subarachnoid space; Widened subarachnoid spaces\n'}


{'id': 'HP_0012705', 'url': 'http://purl.obolibrary.org/obo/HP_0012705', 'lbl': 'Abnormal metabolic brain imaging by MRS', 'desc': 'label: Abnormal metabolic brain imaging by MRS\ndefinition : An anomaly of metabolism in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :\n'}


{'id': 'HP_0012706', 'url': 'http://purl.obolibrary.org/obo/HP_0012706', 'lbl': 'Elevated brain choline level by MRS', 'desc': 'label: Elevated brain choline level by MRS\ndefinition : An increase in the level of choline-containing compounds in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :\n'}


{'id': 'HP_0012707', 'url': 'http://purl.obolibrary.org/obo/HP_0012707', 'lbl': 'Elevated brain lactate level by MRS', 'desc': 'label: Elevated brain lactate level by MRS\ndefinition : An increase in the level of lactate in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :\n'}


{'id': 'HP_0012708', 'url': 'http://purl.obolibrary.org/obo/HP_0012708', 'lbl': 'Reduced brain N-acetyl aspartate level by MRS', 'desc': 'label: Reduced brain N-acetyl aspartate level by MRS\ndefinition : A decrease in the level of N-acetyl aspartate in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :Reduced brain N-acetyl aspartate level by magnetic resonance spectroscopy\n'}


{'id': 'HP_0012709', 'url': 'http://purl.obolibrary.org/obo/HP_0012709', 'lbl': 'Abnormal brain choline/creatine ratio by MRS', 'desc': 'label: Abnormal brain choline/creatine ratio by MRS\ndefinition : A deviation from normal in the ratio of choline to creatine in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :\n'}


{'id': 'HP_0012710', 'url': 'http://purl.obolibrary.org/obo/HP_0012710', 'lbl': 'Ingrown nail', 'desc': 'label: Ingrown nail\ndefinition : Excessive growth of a nail laterally into the nail fold.\nsynonyms :Ingrown nail\n'}


{'id': 'HP_0012711', 'url': 'http://purl.obolibrary.org/obo/HP_0012711', 'lbl': 'Delayed ossification of vertebral epiphysis', 'desc': 'label: Delayed ossification of vertebral epiphysis\ndefinition : A delay in the process of formation and maturation of the epiphysis of one or more vertebrae.\nsynonyms :Delayed maturation of the end part of the vertebral bone\n'}


{'id': 'HP_0012712', 'url': 'http://purl.obolibrary.org/obo/HP_0012712', 'lbl': 'Mild hearing impairment', 'desc': 'label: Mild hearing impairment\ndefinition : The presence of a mild form of hearing impairment.\nsynonyms :Mild hearing impairment\n'}


{'id': 'HP_0012713', 'url': 'http://purl.obolibrary.org/obo/HP_0012713', 'lbl': 'Moderate hearing impairment', 'desc': 'label: Moderate hearing impairment\ndefinition : The presence of a moderate form of hearing impairment.\nsynonyms :Moderate hearing impairment\n'}


{'id': 'HP_0012714', 'url': 'http://purl.obolibrary.org/obo/HP_0012714', 'lbl': 'Severe hearing impairment', 'desc': 'label: Severe hearing impairment\ndefinition : A severe form of hearing impairment.\nsynonyms :Severe deafness; Severe hearing impairment; Severe hearing loss\n'}


{'id': 'HP_0012715', 'url': 'http://purl.obolibrary.org/obo/HP_0012715', 'lbl': 'Profound hearing impairment', 'desc': 'label: Profound hearing impairment\ndefinition : A profound (essentially complete) form of hearing impairment.\nsynonyms :Profound hearing impairment\n'}


{'id': 'HP_0012716', 'url': 'http://purl.obolibrary.org/obo/HP_0012716', 'lbl': 'Moderate conductive hearing impairment', 'desc': 'label: Moderate conductive hearing impairment\ndefinition : The presence of a moderate form of conductive hearing impairment.\nsynonyms :Conductive hearing loss, moderate\n'}


{'id': 'HP_0012717', 'url': 'http://purl.obolibrary.org/obo/HP_0012717', 'lbl': 'Severe conductive hearing impairment', 'desc': 'label: Severe conductive hearing impairment\ndefinition : A severe form of conductive hearing impairment.\nsynonyms :Conductive hearing loss, severe\n'}


{'id': 'HP_0012718', 'url': 'http://purl.obolibrary.org/obo/HP_0012718', 'lbl': 'Morphological abnormality of the gastrointestinal tract', 'desc': 'label: Morphological abnormality of the gastrointestinal tract\ndefinition : Abnormal structure of the gastrointestinal tract.\nsynonyms :Abnormal shape of the digestive system; Morphological abnormality of the GI tract; Morphological anomaly of the digestive system\n'}


{'id': 'HP_0012719', 'url': 'http://purl.obolibrary.org/obo/HP_0012719', 'lbl': 'Functional abnormality of the gastrointestinal tract', 'desc': 'label: Functional abnormality of the gastrointestinal tract\ndefinition : Abnormal functionality of the gastrointestinal tract.\nsynonyms :Functional abnormality of the GI tract; GI dysfunction\n'}


{'id': 'HP_0012720', 'url': 'http://purl.obolibrary.org/obo/HP_0012720', 'lbl': 'Neoplasm of the nose', 'desc': 'label: Neoplasm of the nose\ndefinition : Tumor (An abnormal mass of tissue resulting from abnormally dividing cells) of the nasal cavity.\nsynonyms :Nasal neoplasm; Nasal tumor; Nasal tumour; Neoplasia of the nose; Nose cancer; Tumor of the nose; Tumour of the nose\n'}


{'id': 'HP_0012721', 'url': 'http://purl.obolibrary.org/obo/HP_0012721', 'lbl': 'Venous malformation', 'desc': 'label: Venous malformation\ndefinition : A vascular malformation resulting from a developmental error of venous tissue composed of dysmorphic channels lined by flattened endothelium and exhibiting slow turnover. A venous malformation may present as a blue patch on the skin ranging to a soft blue mass. Venous malformations are easily compressible and usually swell in thewhen venous pressure increases (e.g., when held in a dependent position or when a child cries). They may be relatively localized or quite extensive within an anatomic region.\nsynonyms :Venous malformations\n'}


{'id': 'HP_0012722', 'url': 'http://purl.obolibrary.org/obo/HP_0012722', 'lbl': 'Heart block', 'desc': 'label: Heart block\ndefinition : Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway.\nsynonyms :\n'}


{'id': 'HP_0012723', 'url': 'http://purl.obolibrary.org/obo/HP_0012723', 'lbl': 'Sinoatrial block', 'desc': 'label: Sinoatrial block\ndefinition : Disturbance in the atrial activation that is caused by transient failure of impulse conduction from the sinoatrial node to the cardiac atria.\nsynonyms :\n'}


{'id': 'HP_0012724', 'url': 'http://purl.obolibrary.org/obo/HP_0012724', 'lbl': 'Upper eyelid edema', 'desc': 'label: Upper eyelid edema\ndefinition : Edema in the region of the upper eyelid.\nsynonyms :Cellulitis of upper eyelid; Fullness of upper eyelid; Puffiness of upper eyelid; Swelling of upper eyelid; Upper eyelid oedema\n'}


{'id': 'HP_0012725', 'url': 'http://purl.obolibrary.org/obo/HP_0012725', 'lbl': 'Cutaneous syndactyly', 'desc': 'label: Cutaneous syndactyly\ndefinition : A soft tissue continuity in the A/P axis between two digits that extends distally to at least the level of the proximal interphalangeal joints, or a soft tissue continuity in the A/P axis between two digits that lies significantly distal to the flexion crease that overlies the metacarpophalangeal or metatarsophalangeal joint of the adjacent digits.\nsynonyms :Cutaneous syndactyly of digits; Syndactyly, cutaneous\n'}


{'id': 'HP_0012726', 'url': 'http://purl.obolibrary.org/obo/HP_0012726', 'lbl': 'Episodic hypokalemia', 'desc': 'label: Episodic hypokalemia\ndefinition : An abnormally decreased potassium concentration in the blood occurring periodically with a return to normal between the episodes.\nsynonyms :Recurrent low potassium\n'}


{'id': 'HP_0012727', 'url': 'http://purl.obolibrary.org/obo/HP_0012727', 'lbl': 'Thoracic aortic aneurysm', 'desc': 'label: Thoracic aortic aneurysm\ndefinition : An abnormal localized widening (dilatation) of the thoracic aorta.\nsynonyms :Dilatation of the thoracic aorta\n'}


{'id': 'HP_0012728', 'url': 'http://purl.obolibrary.org/obo/HP_0012728', 'lbl': 'Fusiform descending thoracic aortic aneurysm', 'desc': 'label: Fusiform descending thoracic aortic aneurysm\ndefinition : A concentric abnormal localized widening (dilatation) of the descending thoracic aorta that involves the full circumference of the vessel wall\nsynonyms :Dilatation of the fusiform descending thoracic aorta\n'}


{'id': 'HP_0012729', 'url': 'http://purl.obolibrary.org/obo/HP_0012729', 'lbl': 'Saccular descending thoracic aortic aneurysm', 'desc': 'label: Saccular descending thoracic aortic aneurysm\ndefinition : An eccentric abnormal localized widening (dilatation) of the descending thoracic aorta that involves only a portion of the circumference of the vessel wall\nsynonyms :Dilatation of the saccular descending thoracic aorta\n'}


{'id': 'HP_0012730', 'url': 'http://purl.obolibrary.org/obo/HP_0012730', 'lbl': 'Aglossia', 'desc': 'label: Aglossia\ndefinition : Absence of the tongue owing to a developmental abnormality.\nsynonyms :Missing tongue; Absence of tongue; Failure of development of tongue\n'}


{'id': 'HP_0012731', 'url': 'http://purl.obolibrary.org/obo/HP_0012731', 'lbl': 'Ectopic anterior pituitary gland', 'desc': 'label: Ectopic anterior pituitary gland\ndefinition : Abnormal anatomic location of the anterior pituitary gland.\nsynonyms :\n'}


{'id': 'HP_0012732', 'url': 'http://purl.obolibrary.org/obo/HP_0012732', 'lbl': 'Anorectal anomaly', 'desc': 'label: Anorectal anomaly\ndefinition : An abnormality of the anus or rectum.\nsynonyms :\n'}


{'id': 'HP_0012733', 'url': 'http://purl.obolibrary.org/obo/HP_0012733', 'lbl': 'Macule', 'desc': 'label: Macule\ndefinition : A flat, distinct, discolored area of skin less than 1 cm wide that does not involve any change in the thickness or texture of the skin.\nsynonyms :Flat, discolored area of skin; Flat, discoloured area of skin\n'}


{'id': 'HP_0012734', 'url': 'http://purl.obolibrary.org/obo/HP_0012734', 'lbl': 'Ketotic hypoglycemia', 'desc': 'label: Ketotic hypoglycemia\ndefinition : Low blood glucose is accompanied by elevated levels of ketone bodies in the body.\nsynonyms :Ketotic low blood sugar\n'}


{'id': 'HP_0012735', 'url': 'http://purl.obolibrary.org/obo/HP_0012735', 'lbl': 'Cough', 'desc': 'label: Cough\ndefinition : A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation.\nsynonyms :Cough; Coughing\n'}


{'id': 'HP_0012736', 'url': 'http://purl.obolibrary.org/obo/HP_0012736', 'lbl': 'Profound global developmental delay', 'desc': 'label: Profound global developmental delay\ndefinition : A profound delay in the achievement of motor or mental milestones in the domains of development of a child.\nsynonyms :Global developmental delay, profound; Psychomotor retardation, profound\n'}


{'id': 'HP_0012737', 'url': 'http://purl.obolibrary.org/obo/HP_0012737', 'lbl': 'Small intestinal polyp', 'desc': 'label: Small intestinal polyp\ndefinition : A discrete abnormal tissue mass that protrudes into the lumen of the small intestine and is attached to the intestinal wall either by a stalk, pedunculus, or a broad base.\nsynonyms :\n'}


{'id': 'HP_0012738', 'url': 'http://purl.obolibrary.org/obo/HP_0012738', 'lbl': 'Agenesis of canine', 'desc': 'label: Agenesis of canine\ndefinition : Agenesis of canine tooth.\nsynonyms :Absent canines; Failure of development of canine; Failure of development of eye tooth; Absence of canine; Absence of eye tooth; Missing canine; Missing eye tooth\n'}


{'id': 'HP_0012739', 'url': 'http://purl.obolibrary.org/obo/HP_0012739', 'lbl': 'Agenesis of the small intestine', 'desc': 'label: Agenesis of the small intestine\ndefinition : Failure to develop of the small intestine.\nsynonyms :Small bowel agenesis; Undeveloped small intestine\n'}


{'id': 'HP_0012740', 'url': 'http://purl.obolibrary.org/obo/HP_0012740', 'lbl': 'Papilloma', 'desc': 'label: Papilloma\ndefinition : A tumor of the skin or mucous membrane with finger-like projections.\nsynonyms :\n'}


{'id': 'HP_0012741', 'url': 'http://purl.obolibrary.org/obo/HP_0012741', 'lbl': 'Unilateral cryptorchidism', 'desc': 'label: Unilateral cryptorchidism\ndefinition : Absence of a testis from the scrotum on one side owing to failure of the testis or testes to descend through the inguinal canal to the scrotum.\nsynonyms :Cryptorchidism, unilateral\n'}


{'id': 'HP_0012742', 'url': 'http://purl.obolibrary.org/obo/HP_0012742', 'lbl': 'Thin fingernail', 'desc': 'label: Thin fingernail\ndefinition : Fingernail that appears thin when viewed on end.\nsynonyms :Thin fingernail\n'}


{'id': 'HP_0012743', 'url': 'http://purl.obolibrary.org/obo/HP_0012743', 'lbl': 'Abdominal obesity', 'desc': 'label: Abdominal obesity\ndefinition : Excessive fat around the stomach and abdomen.\nsynonyms :Abdominal obesity; Central obesity\n'}


{'id': 'HP_0012744', 'url': 'http://purl.obolibrary.org/obo/HP_0012744', 'lbl': 'Femoral aplasia', 'desc': 'label: Femoral aplasia\ndefinition : Failure of the femur to develop.\nsynonyms :Absent femur; Absent thighbone; Aplasia of the femur\n'}


{'id': 'HP_0012745', 'url': 'http://purl.obolibrary.org/obo/HP_0012745', 'lbl': 'Short palpebral fissure', 'desc': 'label: Short palpebral fissure\ndefinition : Distance between the medial and lateral canthi is more than 2 SD below the mean for age (objective); or, apparently reduced length of the palpebral fissures.\nsynonyms :Decreased height of palpebral fissure; Short opening between the eyelids; Short palpebral fissures\n'}


{'id': 'HP_0012746', 'url': 'http://purl.obolibrary.org/obo/HP_0012746', 'lbl': 'Thin toenail', 'desc': 'label: Thin toenail\ndefinition : Toenail that appears thin when viewed on end.\nsynonyms :Thin toenail; Thin toenails\n'}


{'id': 'HP_0012747', 'url': 'http://purl.obolibrary.org/obo/HP_0012747', 'lbl': 'Abnormal brainstem MRI signal intensity', 'desc': 'label: Abnormal brainstem MRI signal intensity\ndefinition : A deviation from normal signal on magnetic resonance imaging (MRI) of the brainstem.\nsynonyms :\n'}


{'id': 'HP_0012748', 'url': 'http://purl.obolibrary.org/obo/HP_0012748', 'lbl': 'Focal T2 hyperintense brainstem lesion', 'desc': 'label: Focal T2 hyperintense brainstem lesion\ndefinition : A lighter than expected T2 signal on magnetic resonance imaging (MRI) of the brainstem. This term refers to a localized hyperintensity affecting a particular region of the brainstem.\nsynonyms :\n'}


{'id': 'HP_0012749', 'url': 'http://purl.obolibrary.org/obo/HP_0012749', 'lbl': 'Focal T2 hypointense brainstem lesion', 'desc': 'label: Focal T2 hypointense brainstem lesion\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the brainstem. This term refers to a localized hypointensity affecting a particular region of the brainstem.\nsynonyms :\n'}


{'id': 'HP_0012750', 'url': 'http://purl.obolibrary.org/obo/HP_0012750', 'lbl': 'T2 hypointense brainstem', 'desc': 'label: T2 hypointense brainstem\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the brainstem. This term refers to a diffuse hypointensity affecting the entire brainstem.\nsynonyms :\n'}


{'id': 'HP_0012751', 'url': 'http://purl.obolibrary.org/obo/HP_0012751', 'lbl': 'Abnormal basal ganglia MRI signal intensity', 'desc': 'label: Abnormal basal ganglia MRI signal intensity\ndefinition : A deviation from normal signal on magnetic resonance imaging (MRI) of the basal ganglia.\nsynonyms :\n'}


{'id': 'HP_0012752', 'url': 'http://purl.obolibrary.org/obo/HP_0012752', 'lbl': 'Focal T2 hypointense basal ganglia lesion', 'desc': 'label: Focal T2 hypointense basal ganglia lesion\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the basal ganglia. This term refers to a localized hypointensity affecting a particular region of the basal ganglia.\nsynonyms :\n'}


{'id': 'HP_0012753', 'url': 'http://purl.obolibrary.org/obo/HP_0012753', 'lbl': 'T2 hypointense basal ganglia', 'desc': 'label: T2 hypointense basal ganglia\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the basal ganglia. This term refers to a diffuse hypointensity affecting all of the basal ganglia.\nsynonyms :\n'}


{'id': 'HP_0012754', 'url': 'http://purl.obolibrary.org/obo/HP_0012754', 'lbl': 'CNS hypermyelination', 'desc': 'label: CNS hypermyelination\ndefinition : Increased amount of myelin in the central nervous system.\nsynonyms :\n'}


{'id': 'HP_0012755', 'url': 'http://purl.obolibrary.org/obo/HP_0012755', 'lbl': 'Enlarged brainstem', 'desc': 'label: Enlarged brainstem\ndefinition : Abnormal increase in size of the brainstem.\nsynonyms :\n'}


{'id': 'HP_0012756', 'url': 'http://purl.obolibrary.org/obo/HP_0012756', 'lbl': 'CSF polymorphonuclear pleocytosis', 'desc': 'label: CSF polymorphonuclear pleocytosis\ndefinition : An increased polymorphonuclear cell count in the cerebrospinal fluid.\nsynonyms :\n'}


{'id': 'HP_0012757', 'url': 'http://purl.obolibrary.org/obo/HP_0012757', 'lbl': 'Abnormal neuron morphology', 'desc': 'label: Abnormal neuron morphology\ndefinition : A structural anomaly of a neuron. Neurons are electrically excitable cells that transmit signals throughout the body. Neurons employ both electrical and chemical components in the transmission of information. Neurons are connected to other neurons at synapses and connected to effector organs or cells at neuroeffector junctions.\nsynonyms :Abnormal neuron shape; Abnormal neuronal morphology\n'}


{'id': 'HP_0012758', 'url': 'http://purl.obolibrary.org/obo/HP_0012758', 'lbl': 'Neurodevelopmental delay', 'desc': 'label: Neurodevelopmental delay\ndefinition : Neurodevelopmental delay (NDD) refers to delays in the maturation of the brain and central nervous system; infants and young children with NDD may experience delays in the development of one or more skills including gross motor abilities, fine-motor coordination, language abilities and ability to solve increasingly complex problems.\nsynonyms :NDD\n'}


{'id': 'HP_0012759', 'url': 'http://purl.obolibrary.org/obo/HP_0012759', 'lbl': 'Neurodevelopmental abnormality', 'desc': 'label: Neurodevelopmental abnormality\ndefinition : A deviation from normal of the neurological development of a child, which may include any or all of the aspects of the development of personal, social, gross or fine motor, and cognitive abilities.\nsynonyms :\n'}


{'id': 'HP_0012760', 'url': 'http://purl.obolibrary.org/obo/HP_0012760', 'lbl': 'Reduced social reciprocity', 'desc': 'label: Reduced social reciprocity\ndefinition : A reduced ability to participate in the back-and-forth flow of social interaction, which is normally characterized by an influence of the behavior of one person on the behavior of another person who is in conversation with the first.\nsynonyms :Impaired social reciprocity\n'}


{'id': 'HP_0012761', 'url': 'http://purl.obolibrary.org/obo/HP_0012761', 'lbl': 'Absent mastoid', 'desc': 'label: Absent mastoid\ndefinition : A developmental anomaly in which the mastoid process fails to form and is thus found to be congenitally absent.\nsynonyms :Absent mastoids; Failure of development of mastoid; Mastoid agenesis\n'}


{'id': 'HP_0012762', 'url': 'http://purl.obolibrary.org/obo/HP_0012762', 'lbl': 'Cerebral white matter atrophy', 'desc': 'label: Cerebral white matter atrophy\ndefinition : The presence of atrophy (wasting) of the cerebral white matter.\nsynonyms :\n'}


{'id': 'HP_0012763', 'url': 'http://purl.obolibrary.org/obo/HP_0012763', 'lbl': 'Paroxysmal dyspnea', 'desc': 'label: Paroxysmal dyspnea\ndefinition : A sudden attack of dyspnea that occurs while the affected person is at rest.\nsynonyms :Paroxysmal dyspnoea\n'}


{'id': 'HP_0012764', 'url': 'http://purl.obolibrary.org/obo/HP_0012764', 'lbl': 'Orthopnea', 'desc': 'label: Orthopnea\ndefinition : A sensation of breathlessness in the recumbent position, relieved by sitting or standing.\nsynonyms :\n'}


{'id': 'HP_0012765', 'url': 'http://purl.obolibrary.org/obo/HP_0012765', 'lbl': 'Widened cerebellar subarachnoid space', 'desc': 'label: Widened cerebellar subarachnoid space\ndefinition : An increase in size of the anatomic space between the arachnoid membrane and pia mater in the region surrounding the cerebellum.\nsynonyms :\n'}


{'id': 'HP_0012766', 'url': 'http://purl.obolibrary.org/obo/HP_0012766', 'lbl': 'Widened cerebral subarachnoid space', 'desc': 'label: Widened cerebral subarachnoid space\ndefinition : An increase in size of the anatomic space between the arachnoid membrane and pia mater in the region surrounding the cerebrum.\nsynonyms :\n'}


{'id': 'HP_0012767', 'url': 'http://purl.obolibrary.org/obo/HP_0012767', 'lbl': 'Abnormal placental size', 'desc': 'label: Abnormal placental size\ndefinition : A deviation from normal size of the placenta.\nsynonyms :\n'}


{'id': 'HP_0012768', 'url': 'http://purl.obolibrary.org/obo/HP_0012768', 'lbl': 'Neonatal asphyxia', 'desc': 'label: Neonatal asphyxia\ndefinition : Respiratory failure in the newborn.\nsynonyms :Asphyxia neonatorum\n'}


{'id': 'HP_0012769', 'url': 'http://purl.obolibrary.org/obo/HP_0012769', 'lbl': 'Abnormal arm span', 'desc': "label: Abnormal arm span\ndefinition : A deviation from normal of the length of the arm span (length from one end of an individual's arms measured at the fingertips to the other when raised parallel to the ground at shoulder height at a one-hundred eighty degree angle)\nsynonyms :Abnormal arm span\n"}


{'id': 'HP_0012770', 'url': 'http://purl.obolibrary.org/obo/HP_0012770', 'lbl': 'Reduced arm span', 'desc': "label: Reduced arm span\ndefinition : Decreased length of the arm span (length from one end of an individual's arms measured at the fingertips to the other when raised parallel to the ground at shoulder height at a one-hundred eighty degree angle).\nsynonyms :Reduced arm span\n"}


{'id': 'HP_0012771', 'url': 'http://purl.obolibrary.org/obo/HP_0012771', 'lbl': 'Increased arm span', 'desc': "label: Increased arm span\ndefinition : Increased length of the arm span (length from one end of an individual's arms measured at the fingertips to the other when raised parallel to the ground at shoulder height at a one-hundred eighty degree angle).\nsynonyms :Increased arm span\n"}


{'id': 'HP_0012772', 'url': 'http://purl.obolibrary.org/obo/HP_0012772', 'lbl': 'Abnormal upper to lower segment ratio', 'desc': 'label: Abnormal upper to lower segment ratio\ndefinition : A deviation from normal of the relation between the upper and the lower segment of the body, where the lower segment is defined as the length between the top of pubic symphysis to floor, and the upper segment is defined as the top of head to top of pubic symphysis.\nsynonyms :\n'}


{'id': 'HP_0012773', 'url': 'http://purl.obolibrary.org/obo/HP_0012773', 'lbl': 'Reduced upper to lower segment ratio', 'desc': 'label: Reduced upper to lower segment ratio\ndefinition : Decreased ratio between the upper and the lower segment of the body, where the lower segment is defined as the length between the top of pubic symphysis to floor, and the upper segment is defined as the top of head to top of pubic symphysis. Consider the term Disproportionate tall stature (HP:0001519) if tall stature is also present.\nsynonyms :\n'}


{'id': 'HP_0012774', 'url': 'http://purl.obolibrary.org/obo/HP_0012774', 'lbl': 'Increased upper to lower segment ratio', 'desc': 'label: Increased upper to lower segment ratio\ndefinition : Elevated ratio between the upper and the lower segment of the body, where the lower segment is defined as the length between the top of pubic symphysis to floor, and the upper segment is defined as the top of head to top of pubic symphysis.\nsynonyms :\n'}


{'id': 'HP_0012775', 'url': 'http://purl.obolibrary.org/obo/HP_0012775', 'lbl': 'Stellate iris', 'desc': 'label: Stellate iris\ndefinition : A lacy pattern or iris pigmentation that resembles the spokes of a bicycle wheel.\nsynonyms :\n'}


{'id': 'HP_0012776', 'url': 'http://purl.obolibrary.org/obo/HP_0012776', 'lbl': 'Abnormal ciliary body morphology', 'desc': 'label: Abnormal ciliary body morphology\ndefinition : A structural anomaly of the ciliary body.\nsynonyms :Abnormality of the ciliary body\n'}


{'id': 'HP_0012777', 'url': 'http://purl.obolibrary.org/obo/HP_0012777', 'lbl': 'Retinal neoplasm', 'desc': 'label: Retinal neoplasm\ndefinition : A tumor (abnormal growth of tissue) of the retina.\nsynonyms :\n'}


{'id': 'HP_0012778', 'url': 'http://purl.obolibrary.org/obo/HP_0012778', 'lbl': 'Retinal astrocytic hamartoma', 'desc': 'label: Retinal astrocytic hamartoma\ndefinition : A glial tumor of the retinal nerve fiber layer arising from a retinal astrocyte.\nsynonyms :\n'}


{'id': 'HP_0012779', 'url': 'http://purl.obolibrary.org/obo/HP_0012779', 'lbl': 'Transient hearing impairment', 'desc': 'label: Transient hearing impairment\ndefinition : Hearing loss that occurs acutely and resolves completely.\nsynonyms :\n'}


{'id': 'HP_0012780', 'url': 'http://purl.obolibrary.org/obo/HP_0012780', 'lbl': 'Neoplasm of the ear', 'desc': 'label: Neoplasm of the ear\ndefinition : A tumor (abnormal growth of tissue) of the ear.\nsynonyms :Ear tumor; Ear tumour\n'}


{'id': 'HP_0012781', 'url': 'http://purl.obolibrary.org/obo/HP_0012781', 'lbl': 'Mid-frequency hearing loss', 'desc': 'label: Mid-frequency hearing loss\ndefinition : A type of hearing impairment affecting primarily the middle frequencies of sound (1000 Hz to 3000 Hz).\nsynonyms :\n'}


{'id': 'HP_0012782', 'url': 'http://purl.obolibrary.org/obo/HP_0012782', 'lbl': 'Perilobar nephrogenic rest', 'desc': 'label: Perilobar nephrogenic rest\ndefinition : A type of nephrogenic rest associated with multiple lesions in the periphery of the renal lobe.\nsynonyms :Perilobar nephrogenic rests\n'}


{'id': 'HP_0012783', 'url': 'http://purl.obolibrary.org/obo/HP_0012783', 'lbl': 'Intralobar nephrogenic rest', 'desc': 'label: Intralobar nephrogenic rest\ndefinition : A type of nephrogenic rest usually representing single lesions within the renal lobe, renal sinus, or calyceal walls.\nsynonyms :Intralobar nephrogenic rests\n'}


{'id': 'HP_0012784', 'url': 'http://purl.obolibrary.org/obo/HP_0012784', 'lbl': 'Perinephritis', 'desc': 'label: Perinephritis\ndefinition : Inflammation of the connective and adipose tissues surrounding the kidney.\nsynonyms :\n'}


{'id': 'HP_0012785', 'url': 'http://purl.obolibrary.org/obo/HP_0012785', 'lbl': 'Flexion contracture of finger', 'desc': 'label: Flexion contracture of finger\ndefinition : Chronic loss of joint motion in a finger due to structural changes in non-bony tissue.\nsynonyms :Flexion deformity of finger\n'}


{'id': 'HP_0012786', 'url': 'http://purl.obolibrary.org/obo/HP_0012786', 'lbl': 'Recurrent cystitis', 'desc': 'label: Recurrent cystitis\ndefinition : Repeated infections of the urinary bladder.\nsynonyms :Recurrent bladder infections\n'}


{'id': 'HP_0012787', 'url': 'http://purl.obolibrary.org/obo/HP_0012787', 'lbl': 'Recurrent pyelonephritis', 'desc': 'label: Recurrent pyelonephritis\ndefinition : Repeated episodes of pyelonephritis.\nsynonyms :\n'}


{'id': 'HP_0012788', 'url': 'http://purl.obolibrary.org/obo/HP_0012788', 'lbl': 'Reticulate pigmentation of oral mucosa', 'desc': 'label: Reticulate pigmentation of oral mucosa\ndefinition : A net-like pattern of increased pigmentation of the oral cavity.\nsynonyms :Mottled pigmentation of oral mucosa; Reticulate pigmentation of oral mucous membrane\n'}


{'id': 'HP_0012789', 'url': 'http://purl.obolibrary.org/obo/HP_0012789', 'lbl': 'Hypoplasia of the calcaneus', 'desc': 'label: Hypoplasia of the calcaneus\ndefinition : Underdevelopment of the heel bone.\nsynonyms :Hypoplastic calcaneus; Small heel bone; Underdeveloped heel bone\n'}


{'id': 'HP_0012790', 'url': 'http://purl.obolibrary.org/obo/HP_0012790', 'lbl': 'Abnormal intramembranous ossification', 'desc': 'label: Abnormal intramembranous ossification\ndefinition : An anomaly in the process of intramembranous ossification by which flat bones (cranial bones of the skull, i.e., the frontal, parietal, occipital, and temporal bones, and the clavicles) are formed.\nsynonyms :Abnormal intramembranous bone ossification\n'}


{'id': 'HP_0012791', 'url': 'http://purl.obolibrary.org/obo/HP_0012791', 'lbl': 'Abnormal humeral ossification', 'desc': 'label: Abnormal humeral ossification\ndefinition : An anomaly of the process of formation of bone in the humerus.\nsynonyms :Abnormal maturation of long bone in upper arm\n'}


{'id': 'HP_0012792', 'url': 'http://purl.obolibrary.org/obo/HP_0012792', 'lbl': 'Absent ossification of thoracic vertebral bodies', 'desc': 'label: Absent ossification of thoracic vertebral bodies\ndefinition : A lack of bone mineralization of one or more body of thoracic vertebra.\nsynonyms :\n'}


{'id': 'HP_0012793', 'url': 'http://purl.obolibrary.org/obo/HP_0012793', 'lbl': 'Kinked brainstem', 'desc': 'label: Kinked brainstem\ndefinition : A kinked appearance of the brainstem, i.e., an exaggerated flexure.\nsynonyms :Kinked brain stem\n'}


{'id': 'HP_0012794', 'url': 'http://purl.obolibrary.org/obo/HP_0012794', 'lbl': 'Periventricular white matter hypodensities', 'desc': 'label: Periventricular white matter hypodensities\ndefinition : Multiple areas of darker than expected signal on magnetic resonance imaging emanating from the cerebral white matter that surrounds the cerebral ventricles.\nsynonyms :Periventricular cerebral white matter hypodensities\n'}


{'id': 'HP_0012795', 'url': 'http://purl.obolibrary.org/obo/HP_0012795', 'lbl': 'Abnormal optic disc morphology', 'desc': 'label: Abnormal optic disc morphology\ndefinition : A morphological abnormality of the optic disc, i.e., of the portion of the optic nerve clinically visible on fundoscopic examination.\nsynonyms :\n'}


{'id': 'HP_0012796', 'url': 'http://purl.obolibrary.org/obo/HP_0012796', 'lbl': 'Increased cup-to-disc ratio', 'desc': 'label: Increased cup-to-disc ratio\ndefinition : An elevation in the ratio of the diameter of the cup of the optic disc to the total diameter of the disc. The optic disc has an orange-pink rim with a pale centre (the cup) that does not contain neuroretinal tissue. An increase in this ratio therefore may indicate a decrease in the quantity of healthy neuroretinal cells.\nsynonyms :Elevated cup to disc ratio; Increased cup disc ratio\n'}


{'id': 'HP_0012797', 'url': 'http://purl.obolibrary.org/obo/HP_0012797', 'lbl': 'Lymphatic vessel neoplasm', 'desc': 'label: Lymphatic vessel neoplasm\ndefinition : A benign or malignant neoplasm arising from the lymphatic vessels.\nsynonyms :Lymphatic vessel tumor; Lymphatic vessel tumour\n'}


{'id': 'HP_0012798', 'url': 'http://purl.obolibrary.org/obo/HP_0012798', 'lbl': 'Pulmonary lymphangiomyomatosis', 'desc': 'label: Pulmonary lymphangiomyomatosis\ndefinition : Infiltration of smooth muscle-like cells in lymph vessels as well as the lung (pleura, alveolar septa, bronchi, pulmonary vessels and lymphatics as well as lymph nodes, especially in posterior mediastinum and retroperitoneum). Focal emphysema can develop because of airway narrowing, and the thoracic duct may be obliterated. Pulmonary lymphangiomyomatosis may lead to multiple small cysts with a hamartomatous proliferation of smooth muscle in their walls.\nsynonyms :Pulmonary myomatosis; Lymphangioleiomyomatosis\n'}


{'id': 'HP_0012799', 'url': 'http://purl.obolibrary.org/obo/HP_0012799', 'lbl': 'Unilateral facial palsy', 'desc': 'label: Unilateral facial palsy\ndefinition : One-sided weakness of the muscles of facial expression and eye closure.\nsynonyms :Facial droop; Paralysis of one side of the face; Unilateral facial muscle paralysis; Unilateral facial muscle weakness; Unilateral facial paralysis; Unilateral facial weakness; Weakness of one side of the face\n'}


{'id': 'HP_0012800', 'url': 'http://purl.obolibrary.org/obo/HP_0012800', 'lbl': 'Accessory cranial suture', 'desc': 'label: Accessory cranial suture\ndefinition : A cranial suture that is in addition to canonical membrane-covered openings in the incompletely ossified skull of the fetus or newborn infant.\nsynonyms :Extra cranial suture; Supernumary cranial suture; Accessory fontanelle; Extra fontanelle; Supernumary fontanelle\n'}


{'id': 'HP_0012801', 'url': 'http://purl.obolibrary.org/obo/HP_0012801', 'lbl': 'Narrow jaw', 'desc': 'label: Narrow jaw\ndefinition : Bigonial distance (lower facial width) more than 2 standard deviations below the mean (objective); or an apparently decreased width of the lower jaw (mandible) when viewed from the front (subjective).\nsynonyms :Narrow jaw; Narrow lower face; Narrow lower jaw; Narrow mandible; Thin lower face; Thin lower jaw\n'}


{'id': 'HP_0012802', 'url': 'http://purl.obolibrary.org/obo/HP_0012802', 'lbl': 'Broad jaw', 'desc': 'label: Broad jaw\ndefinition : Bigonial distance (lower facial width) more than 2 SD above the mean (objective); or an apparently increased width of the lower jaw (mandible) when viewed from the front (subjective).\nsynonyms :Broad jaw; Broad lower face; Broad mandible; Wide jaw; Wide mandible\n'}


{'id': 'HP_0012803', 'url': 'http://purl.obolibrary.org/obo/HP_0012803', 'lbl': 'Anisometropia', 'desc': 'label: Anisometropia\ndefinition : Inequality of refractive power of the two eyes.\nsynonyms :\n'}


{'id': 'HP_0012804', 'url': 'http://purl.obolibrary.org/obo/HP_0012804', 'lbl': 'Corneal ulceration', 'desc': 'label: Corneal ulceration\ndefinition : Disruption of the epithelial layer of the cornea with involvement of the underlying stroma.\nsynonyms :Corneal ulcer; Corneal ulcerations\n'}


{'id': 'HP_0012805', 'url': 'http://purl.obolibrary.org/obo/HP_0012805', 'lbl': 'Iris transillumination defect', 'desc': 'label: Iris transillumination defect\ndefinition : Transmission of light through the iris as visualized upon slit lamp examination or infrared iris transillumination videography. The light passes through defects in the pigmentation of the iris.\nsynonyms :\n'}


{'id': 'HP_0012806', 'url': 'http://purl.obolibrary.org/obo/HP_0012806', 'lbl': 'Proboscis', 'desc': 'label: Proboscis\ndefinition : A fleshy, tube-like structure usually located in the midline of the face or just to one side of the midline.\nsynonyms :\n'}


{'id': 'HP_0012807', 'url': 'http://purl.obolibrary.org/obo/HP_0012807', 'lbl': 'High insertion of columella', 'desc': 'label: High insertion of columella\ndefinition : Insertion of the posterior columella superior to the nasal base.\nsynonyms :Ala lower than columella; Columella, high insertion\n'}


{'id': 'HP_0012808', 'url': 'http://purl.obolibrary.org/obo/HP_0012808', 'lbl': 'Abnormal nasal base norphology', 'desc': 'label: Abnormal nasal base norphology\ndefinition : An anomaly of the nasal base, which can be conceived of as an imaginary line between the most lateral points of the external inferior attachments of the alae nasi to the face.\nsynonyms :Abnormal nasal base; Abnormality of base of nose; Anomaly of base of nose; Anomaly of nasal base; Deformity of base of nose; Deformity of nasal base; Malformation of base of nose; Malformation of nasal base\n'}


{'id': 'HP_0012809', 'url': 'http://purl.obolibrary.org/obo/HP_0012809', 'lbl': 'Narrow nasal base', 'desc': 'label: Narrow nasal base\ndefinition : Decreased distance between the attachments of the alae nasi to the face.\nsynonyms :Decreased width of base of nose; Decreased width of nasal base; Narrow base of nose; Narrow nasal base; Thin base of nose; Thin nasal base\n'}


{'id': 'HP_0012810', 'url': 'http://purl.obolibrary.org/obo/HP_0012810', 'lbl': 'Wide nasal base', 'desc': 'label: Wide nasal base\ndefinition : Increased distance between the attachments of the alae nasi to the face.\nsynonyms :Broad base of nose; Broad nasal base; Increased width of base of nose; Increased width of nasal base; Wide base of nose; Wide nasal base\n'}


{'id': 'HP_0012811', 'url': 'http://purl.obolibrary.org/obo/HP_0012811', 'lbl': 'Wide nasal ridge', 'desc': 'label: Wide nasal ridge\ndefinition : Increased width of the nasal ridge.\nsynonyms :Broad dorsum of nose; Broad nasal dorsum; Increased width of dorsum of nose; Increased width of nasal dorsum; Increased width of nasal ridge; Nasal ridge, wide; Wide dorsum of nose; Wide nasal dorsum; Wide nasal ridge; Broad nasal ridge\n'}


{'id': 'HP_0012812', 'url': 'http://purl.obolibrary.org/obo/HP_0012812', 'lbl': 'Fullness of paranasal tissue', 'desc': 'label: Fullness of paranasal tissue\ndefinition : Increased bulk of tissue alongside the nose. The fullness can be caused by both bony and soft tissues.\nsynonyms :Fullness of tissue around the nose; Laterally built up nose; Paranasal fullness; Thick paranasal tissue; Thick tissue around the nose; Hyperplasia of paranasal tissue; Hypertrophy of paranasal tissue\n'}


{'id': 'HP_0012813', 'url': 'http://purl.obolibrary.org/obo/HP_0012813', 'lbl': 'Unilateral breast hypoplasia', 'desc': 'label: Unilateral breast hypoplasia\ndefinition : Underdevelopment of the breast on one side only.\nsynonyms :One underdeveloped breast\n'}


{'id': 'HP_0012814', 'url': 'http://purl.obolibrary.org/obo/HP_0012814', 'lbl': 'Bilateral breast hypoplasia', 'desc': 'label: Bilateral breast hypoplasia\ndefinition : Underdevelopment of the breast on both sides.\nsynonyms :Two underdeveloped breasts\n'}


{'id': 'HP_0012815', 'url': 'http://purl.obolibrary.org/obo/HP_0012815', 'lbl': 'Hypoplastic female external genitalia', 'desc': 'label: Hypoplastic female external genitalia\ndefinition : Underdevelopment of part or all of the female external reproductive organs (which include the mons pubis, labia majora, labia minora, Bartholin glands, and clitoris).\nsynonyms :Underdeveloped female external genitalia\n'}


{'id': 'HP_0012816', 'url': 'http://purl.obolibrary.org/obo/HP_0012816', 'lbl': 'Right ventricular noncompaction cardiomyopathy', 'desc': 'label: Right ventricular noncompaction cardiomyopathy\ndefinition : A predominantly right ventricular variant of isolated noncompaction cardiomyopathy.\nsynonyms :\n'}


{'id': 'HP_0012817', 'url': 'http://purl.obolibrary.org/obo/HP_0012817', 'lbl': 'Noncompaction cardiomyopathy', 'desc': 'label: Noncompaction cardiomyopathy\ndefinition : A type of cardiomyopathy characterized anatomically by deep trabeculations in the ventricular wall, which define recesses communicating with the main ventricular chamber.\nsynonyms :Noncompaction of the ventricular myocardium; Spongiform cardiomyopathy\n'}


{'id': 'HP_0012818', 'url': 'http://purl.obolibrary.org/obo/HP_0012818', 'lbl': 'Biventricular noncompaction cardiomyopathy', 'desc': 'label: Biventricular noncompaction cardiomyopathy\ndefinition : Noncompaction cardiomyopathy that affects both ventricles.\nsynonyms :\n'}


{'id': 'HP_0012819', 'url': 'http://purl.obolibrary.org/obo/HP_0012819', 'lbl': 'Myocarditis', 'desc': 'label: Myocarditis\ndefinition : Inflammation of the myocardium.\nsynonyms :Inflammation of heart muscle\n'}


{'id': 'HP_0012820', 'url': 'http://purl.obolibrary.org/obo/HP_0012820', 'lbl': 'Bilateral vocal cord paralysis', 'desc': 'label: Bilateral vocal cord paralysis\ndefinition : A loss of the ability to move the vocal fold on both sides.\nsynonyms :\n'}


{'id': 'HP_0012821', 'url': 'http://purl.obolibrary.org/obo/HP_0012821', 'lbl': 'Unilateral vocal cord paresis', 'desc': 'label: Unilateral vocal cord paresis\ndefinition : Decreased strength of the vocal fold on one side.\nsynonyms :\n'}


{'id': 'HP_0012822', 'url': 'http://purl.obolibrary.org/obo/HP_0012822', 'lbl': 'Bilateral vocal cord paresis', 'desc': 'label: Bilateral vocal cord paresis\ndefinition : Decreased strength of the vocal fold on both sides.\nsynonyms :\n'}


{'id': 'HP_0012823', 'url': 'http://purl.obolibrary.org/obo/HP_0012823', 'lbl': 'Clinical modifier', 'desc': 'label: Clinical modifier\ndefinition : This subontology is designed to provide terms to characterize and specify the phenotypic abnormalities defined in the Phenotypic abnormality subontology, with respect to severity, laterality, age of onset, and other aspects.\nsynonyms :Phenotypic modifier\n'}


{'id': 'HP_0012824', 'url': 'http://purl.obolibrary.org/obo/HP_0012824', 'lbl': 'Severity', 'desc': 'label: Severity\ndefinition : The intensity or degree of a manifestation.\nsynonyms :Intensity\n'}


{'id': 'HP_0012825', 'url': 'http://purl.obolibrary.org/obo/HP_0012825', 'lbl': 'Mild', 'desc': 'label: Mild\ndefinition : Having a relatively minor degree of severity. For quantitative traits, a deviation of between two and three standard deviations from the appropriate population mean.\nsynonyms :Mild\n'}


{'id': 'HP_0012826', 'url': 'http://purl.obolibrary.org/obo/HP_0012826', 'lbl': 'Moderate', 'desc': 'label: Moderate\ndefinition : Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean.\nsynonyms :\n'}


{'id': 'HP_0012827', 'url': 'http://purl.obolibrary.org/obo/HP_0012827', 'lbl': 'Borderline', 'desc': 'label: Borderline\ndefinition : Having a minor degree of severity that is considered to be on the boundary between the normal and the abnormal ranges. For quantitative traits, a deviation of that is less than two standard deviations from the appropriate population mean.\nsynonyms :Borderline\n'}


{'id': 'HP_0012828', 'url': 'http://purl.obolibrary.org/obo/HP_0012828', 'lbl': 'Severe', 'desc': 'label: Severe\ndefinition : Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean.\nsynonyms :Severe\n'}


{'id': 'HP_0012829', 'url': 'http://purl.obolibrary.org/obo/HP_0012829', 'lbl': 'Profound', 'desc': 'label: Profound\ndefinition : Having an extremely high degree of severity. For quantitative traits, a deviation of more than five standard deviations from the appropriate population mean.\nsynonyms :Profound\n'}


{'id': 'HP_0012830', 'url': 'http://purl.obolibrary.org/obo/HP_0012830', 'lbl': 'Position', 'desc': 'label: Position\ndefinition : The anatomical localization of the specified phenotypic abnormality.\nsynonyms :\n'}


{'id': 'HP_0012831', 'url': 'http://purl.obolibrary.org/obo/HP_0012831', 'lbl': 'Laterality', 'desc': 'label: Laterality\ndefinition : The localization with respect to the side of the body of the specified phenotypic abnormality.\nsynonyms :\n'}


{'id': 'HP_0012832', 'url': 'http://purl.obolibrary.org/obo/HP_0012832', 'lbl': 'Bilateral', 'desc': 'label: Bilateral\ndefinition : Being present on both sides of the body.\nsynonyms :\n'}


{'id': 'HP_0012833', 'url': 'http://purl.obolibrary.org/obo/HP_0012833', 'lbl': 'Unilateral', 'desc': 'label: Unilateral\ndefinition : Being present on only the left or only the right side of the body.\nsynonyms :\n'}


{'id': 'HP_0012834', 'url': 'http://purl.obolibrary.org/obo/HP_0012834', 'lbl': 'Right', 'desc': 'label: Right\ndefinition : Being located on the right side of the body.\nsynonyms :Right-sided\n'}


{'id': 'HP_0012835', 'url': 'http://purl.obolibrary.org/obo/HP_0012835', 'lbl': 'Left', 'desc': 'label: Left\ndefinition : Being located on the left side of the body.\nsynonyms :Left-sided\n'}


{'id': 'HP_0012836', 'url': 'http://purl.obolibrary.org/obo/HP_0012836', 'lbl': 'Spatial pattern', 'desc': 'label: Spatial pattern\ndefinition : The pattern by which a phenotype affects one or more regions of the body.\nsynonyms :\n'}


{'id': 'HP_0012837', 'url': 'http://purl.obolibrary.org/obo/HP_0012837', 'lbl': 'Generalized', 'desc': 'label: Generalized\ndefinition : Affecting all regions without specificity of distribution.\nsynonyms :Generalised\n'}


{'id': 'HP_0012838', 'url': 'http://purl.obolibrary.org/obo/HP_0012838', 'lbl': 'Localized', 'desc': 'label: Localized\ndefinition : Being confined or restricted to a particular location.\nsynonyms :Localised; Localized\n'}


{'id': 'HP_0012839', 'url': 'http://purl.obolibrary.org/obo/HP_0012839', 'lbl': 'Distal', 'desc': 'label: Distal\ndefinition : Localized away from the central point of the body.\nsynonyms :Outermost\n'}


{'id': 'HP_0012840', 'url': 'http://purl.obolibrary.org/obo/HP_0012840', 'lbl': 'Proximal', 'desc': 'label: Proximal\ndefinition : Localized close to the central point of the body.\nsynonyms :\n'}


{'id': 'HP_0012841', 'url': 'http://purl.obolibrary.org/obo/HP_0012841', 'lbl': 'Retinal vascular tortuosity', 'desc': 'label: Retinal vascular tortuosity\ndefinition : The presence of an increased number of twists and turns of the retinal blood vessels.\nsynonyms :Tortuous retinal vessels\n'}


{'id': 'HP_0012842', 'url': 'http://purl.obolibrary.org/obo/HP_0012842', 'lbl': 'Skin appendage neoplasm', 'desc': 'label: Skin appendage neoplasm\ndefinition : A benign or malignant neoplasm that arises from the hair follicles, sebaceous glands, or sweat glands.\nsynonyms :Skin adnexal neoplasm; Skin adnexal tumor; Skin adnexal tumour\n'}


{'id': 'HP_0012843', 'url': 'http://purl.obolibrary.org/obo/HP_0012843', 'lbl': 'Hair follicle neoplasm', 'desc': 'label: Hair follicle neoplasm\ndefinition : An uncontrolled autonomous cell-proliferation originating in a hair follicle, which is an epidermal adnexal structures responsible for hair growth.\nsynonyms :\n'}


{'id': 'HP_0012844', 'url': 'http://purl.obolibrary.org/obo/HP_0012844', 'lbl': 'Trichilemmoma', 'desc': 'label: Trichilemmoma\ndefinition : A benign tumor originating from the outer root sheath of the hair follicle.\nsynonyms :Tricholemmoma\n'}


{'id': 'HP_0012845', 'url': 'http://purl.obolibrary.org/obo/HP_0012845', 'lbl': 'Single trichilemmoma', 'desc': 'label: Single trichilemmoma\ndefinition : Presence of a unitary trichilemmoma, a benign tumor originating from the outer root sheath of the hair follicle.\nsynonyms :\n'}


{'id': 'HP_0012846', 'url': 'http://purl.obolibrary.org/obo/HP_0012846', 'lbl': 'Multiple trichilemmomata', 'desc': 'label: Multiple trichilemmomata\ndefinition : Presence of multiple trichilemmomata, a benign tumor originating from the outer root sheath of the hair follicle.\nsynonyms :Multiple trichilemmomas\n'}


{'id': 'HP_0012847', 'url': 'http://purl.obolibrary.org/obo/HP_0012847', 'lbl': 'Epilepsia partialis continua', 'desc': "label: Epilepsia partialis continua\ndefinition : Epilepsia partialis continua (also called Kojevnikov's or Kozhevnikov's epilepsia) is a type of focal motor status epilepticus characterized by repeated stereotyped simple motor manifestations such as jerks, typically of a limb or the face, recurring every few seconds or minutes for extended periods (days or years).\nsynonyms :Epilepsia partialis continua of Kojevnikov; Kojevnikov's epilepsia; Kozhevnikov's epilepsia\n"}


{'id': 'HP_0012848', 'url': 'http://purl.obolibrary.org/obo/HP_0012848', 'lbl': 'Small intestinal stenosis', 'desc': 'label: Small intestinal stenosis\ndefinition : The narrowing or partial blockage of a portion of the small intestine.\nsynonyms :Narrowing of small intestine\n'}


{'id': 'HP_0012849', 'url': 'http://purl.obolibrary.org/obo/HP_0012849', 'lbl': 'Small intestinal bleeding', 'desc': 'label: Small intestinal bleeding\ndefinition : Bleeding from the small intestine.\nsynonyms :Small intestinal bleeding; Small intestinal haemorrhage; Small intestinal hemorrhage\n'}


{'id': 'HP_0012850', 'url': 'http://purl.obolibrary.org/obo/HP_0012850', 'lbl': 'Small intestinal dysmotility', 'desc': 'label: Small intestinal dysmotility\ndefinition : Abnormal small intestinal contractions, such as spasms and intestinal paralysis related to the loss of the ability of the gut to coordinate muscular activity because of endogenous or exogenous causes.\nsynonyms :\n'}


{'id': 'HP_0012851', 'url': 'http://purl.obolibrary.org/obo/HP_0012851', 'lbl': 'Colonic stenosis', 'desc': 'label: Colonic stenosis\ndefinition : A narrowing of a segment of colon whereby bowel continuity is maintained.\nsynonyms :Narrowing of the colon; Stenosis of the colon\n'}


{'id': 'HP_0012852', 'url': 'http://purl.obolibrary.org/obo/HP_0012852', 'lbl': 'Hepatic bridging fibrosis', 'desc': 'label: Hepatic bridging fibrosis\ndefinition : Hepatic fibrosis that reaches from a portal area to another portal area.\nsynonyms :\n'}


{'id': 'HP_0012853', 'url': 'http://purl.obolibrary.org/obo/HP_0012853', 'lbl': 'Scrotal hypospadias', 'desc': 'label: Scrotal hypospadias\ndefinition : Hypospadias with location of the urethral meatus in the scrotum.\nsynonyms :\n'}


{'id': 'HP_0012854', 'url': 'http://purl.obolibrary.org/obo/HP_0012854', 'lbl': 'Midshaft hypospadias', 'desc': 'label: Midshaft hypospadias\ndefinition : Hypospadias with location of the urethral meatus in the middle of the inferior shaft of the penis.\nsynonyms :\n'}


{'id': 'HP_0012855', 'url': 'http://purl.obolibrary.org/obo/HP_0012855', 'lbl': 'Scrotal hyperpigmentation', 'desc': 'label: Scrotal hyperpigmentation\ndefinition : Increased pigmentation (skin color) of the scrotum.\nsynonyms :Hyperpigmentation of the scrotum; Hyperpigmented scrotum; Increased pigmentation in scrotum\n'}


{'id': 'HP_0012856', 'url': 'http://purl.obolibrary.org/obo/HP_0012856', 'lbl': 'Abnormal scrotal rugation', 'desc': 'label: Abnormal scrotal rugation\ndefinition : Anomaly of the folded ridges (wrinkles) of skin of the scrotum.\nsynonyms :\n'}


{'id': 'HP_0012857', 'url': 'http://purl.obolibrary.org/obo/HP_0012857', 'lbl': 'Increased scrotal rugation', 'desc': 'label: Increased scrotal rugation\ndefinition : Increased number or density of the folded ridges (wrinkles) of skin of the scrotum.\nsynonyms :\n'}


{'id': 'HP_0012858', 'url': 'http://purl.obolibrary.org/obo/HP_0012858', 'lbl': 'Decreased scrotal rugation', 'desc': 'label: Decreased scrotal rugation\ndefinition : Decreased number or density of the folded ridges (wrinkles) of skin of the scrotum.\nsynonyms :\n'}


{'id': 'HP_0012859', 'url': 'http://purl.obolibrary.org/obo/HP_0012859', 'lbl': 'Esophageal leukoplakia', 'desc': 'label: Esophageal leukoplakia\ndefinition : A white patch or plaque occurring on the surface of the esophageal mucous membranes that cannot be rubbed off and cannot be characterized clinically as any other disease.\nsynonyms :Esophageal epidermoid metaplasia\n'}


{'id': 'HP_0012860', 'url': 'http://purl.obolibrary.org/obo/HP_0012860', 'lbl': 'Testicular fibrosis', 'desc': 'label: Testicular fibrosis\ndefinition : Formation of excess connective tissue in the testicle.\nsynonyms :Fibrotic testes; Fibrotic testicle\n'}


{'id': 'HP_0012861', 'url': 'http://purl.obolibrary.org/obo/HP_0012861', 'lbl': 'Ovotestis', 'desc': 'label: Ovotestis\ndefinition : A gonad that contains both ovarian follicles and testicular tubular elements.\nsynonyms :\n'}


{'id': 'HP_0012862', 'url': 'http://purl.obolibrary.org/obo/HP_0012862', 'lbl': 'Abnormal germ cell morphology', 'desc': 'label: Abnormal germ cell morphology\ndefinition : Any structural anomaly of a reproductive cell.\nsynonyms :Abnormal shape of a reproductive cell; Abnormally shaped germ cell; Abnormally shaped reproductive cell\n'}


{'id': 'HP_0012863', 'url': 'http://purl.obolibrary.org/obo/HP_0012863', 'lbl': 'Abnormal male germ cell morphology', 'desc': 'label: Abnormal male germ cell morphology\ndefinition : A structural anomaly of a male reproductive cell.\nsynonyms :\n'}


{'id': 'HP_0012864', 'url': 'http://purl.obolibrary.org/obo/HP_0012864', 'lbl': 'Abnormal sperm morphology', 'desc': 'label: Abnormal sperm morphology\ndefinition : A structural anomaly of sperm.\nsynonyms :Abnormal shape of sperm; Teratospermia; Teratozoospermia\n'}


{'id': 'HP_0012865', 'url': 'http://purl.obolibrary.org/obo/HP_0012865', 'lbl': 'Abnormal sperm head morphology', 'desc': 'label: Abnormal sperm head morphology\ndefinition : A structural abnormality of the sperm head.\nsynonyms :Sperm head anomaly\n'}


{'id': 'HP_0012866', 'url': 'http://purl.obolibrary.org/obo/HP_0012866', 'lbl': 'Abnormal sperm neck morphology', 'desc': 'label: Abnormal sperm neck morphology\ndefinition : A structural abnormality of the sperm neck.\nsynonyms :Sperm neck anomaly\n'}


{'id': 'HP_0012867', 'url': 'http://purl.obolibrary.org/obo/HP_0012867', 'lbl': 'Abnormal sperm mid-piece morphology', 'desc': 'label: Abnormal sperm mid-piece morphology\ndefinition : A structural abnormality of the sperm mid-piece.\nsynonyms :Sperm mid-piece anomaly\n'}


{'id': 'HP_0012868', 'url': 'http://purl.obolibrary.org/obo/HP_0012868', 'lbl': 'Abnormal sperm tail morphology', 'desc': 'label: Abnormal sperm tail morphology\ndefinition : A structural abnormality of the sperm tail.\nsynonyms :Sperm tail anomaly\n'}


{'id': 'HP_0012869', 'url': 'http://purl.obolibrary.org/obo/HP_0012869', 'lbl': 'Acephalic spermatozoa', 'desc': 'label: Acephalic spermatozoa\ndefinition : Spermatozoa with very small cranial ends devoid of any nuclear material, that is, lacking a typical sperm head.\nsynonyms :\n'}


{'id': 'HP_0012870', 'url': 'http://purl.obolibrary.org/obo/HP_0012870', 'lbl': 'Vanishing testis', 'desc': 'label: Vanishing testis\ndefinition : A condition which is considered to be due to the subsequent atrophy and disappearance in fetal life of an initially normal testis. In the presence of spermatic cord structures is evidence of the presence of the testis in early intrauterine life. When associated with a blind-ending spermatic cord, this entity is named as his absence of a testis in an otherwise normal 46XY male is usually unilateral and is assumed to be a consequence of intrauterine or perinatal torsion or infarction.\nsynonyms :Vanishing testis; Testicular regression syndrome\n'}


{'id': 'HP_0012871', 'url': 'http://purl.obolibrary.org/obo/HP_0012871', 'lbl': 'Varicocele', 'desc': 'label: Varicocele\ndefinition : A varicocele is a widening of the veins along the spermatic cord, leading to enlarged, twisted veins in the scrotum, and manifested clinically by a painless testicle lump, scrotal swelling, or bulge in the scrotum.\nsynonyms :Vaginal varicocele\n'}


{'id': 'HP_0012872', 'url': 'http://purl.obolibrary.org/obo/HP_0012872', 'lbl': 'Abnormal vas deferens morphology', 'desc': 'label: Abnormal vas deferens morphology\ndefinition : A structural anomaly of the secretory duct of the testicle that carries spermatozoa from the epididymis to the prostatic urethra where it terminates to form ejaculatory duct.\nsynonyms :\n'}


{'id': 'HP_0012873', 'url': 'http://purl.obolibrary.org/obo/HP_0012873', 'lbl': 'Absent vas deferens', 'desc': 'label: Absent vas deferens\ndefinition : Aplasia (congenital absence) of the vas deferens.\nsynonyms :Absent deferent duct; Absent ductus deferens; Congenital absence of the vas deferens\n'}


{'id': 'HP_0012874', 'url': 'http://purl.obolibrary.org/obo/HP_0012874', 'lbl': 'Abnormal male reproductive system physiology', 'desc': 'label: Abnormal male reproductive system physiology\ndefinition : An abnormal functionality of the male genital system.\nsynonyms :Abnormal male genital system physiology\n'}


{'id': 'HP_0012875', 'url': 'http://purl.obolibrary.org/obo/HP_0012875', 'lbl': 'Abnormal ejaculation', 'desc': 'label: Abnormal ejaculation\ndefinition : Abnormality in the process of ejection of semen (usually carrying sperm) from the male reproductive tract.\nsynonyms :\n'}


{'id': 'HP_0012876', 'url': 'http://purl.obolibrary.org/obo/HP_0012876', 'lbl': 'Premature ejaculation', 'desc': 'label: Premature ejaculation\ndefinition : The emission of semen and seminal fluid during the act of preparation for sexual intercourse, i.e. before there is penetration, or shortly after penetration.\nsynonyms :Premature ejaculation\n'}


{'id': 'HP_0012877', 'url': 'http://purl.obolibrary.org/obo/HP_0012877', 'lbl': 'Retrograde ejaculation', 'desc': 'label: Retrograde ejaculation\ndefinition : The emission of semen and seminal fluid into the bladder instead of through the penis during orgasm.\nsynonyms :\n'}


{'id': 'HP_0012878', 'url': 'http://purl.obolibrary.org/obo/HP_0012878', 'lbl': 'Retarded ejaculation', 'desc': 'label: Retarded ejaculation\ndefinition : Difficulty of a male in achieving orgasm.\nsynonyms :Delayed ejaculation\n'}


{'id': 'HP_0012879', 'url': 'http://purl.obolibrary.org/obo/HP_0012879', 'lbl': 'Anejaculation', 'desc': 'label: Anejaculation\ndefinition : Inability to ejaculate.\nsynonyms :Ejaculatory incompetence\n'}


{'id': 'HP_0012880', 'url': 'http://purl.obolibrary.org/obo/HP_0012880', 'lbl': 'Abnormal labia minora morphology', 'desc': 'label: Abnormal labia minora morphology\ndefinition : An anomaly of the labia minora, the folds of skin between the outer labia.\nsynonyms :Abnormality of the inner vaginal lips; Abnormality of the labia minora\n'}


{'id': 'HP_0012881', 'url': 'http://purl.obolibrary.org/obo/HP_0012881', 'lbl': 'Abnormal labia majora morphology', 'desc': 'label: Abnormal labia majora morphology\ndefinition : An anomaly of the outer labia.\nsynonyms :Abnormality of the labia majora; Abnormality of vaginal lips\n'}


{'id': 'HP_0012882', 'url': 'http://purl.obolibrary.org/obo/HP_0012882', 'lbl': 'Hyperplastic labia majora', 'desc': 'label: Hyperplastic labia majora\ndefinition : Overgrowth of the outer labia.\nsynonyms :Enlarged labia majora; Hyperplasia of labia majora\n'}


{'id': 'HP_0012883', 'url': 'http://purl.obolibrary.org/obo/HP_0012883', 'lbl': 'Fallopian tube cyst', 'desc': 'label: Fallopian tube cyst\ndefinition : A fluid filled sac located in the Fallopian tube.\nsynonyms :\n'}


{'id': 'HP_0012884', 'url': 'http://purl.obolibrary.org/obo/HP_0012884', 'lbl': 'Fallopian tube torsion', 'desc': 'label: Fallopian tube torsion\ndefinition : A twisting of the Fallopian tube. Sudden onset with sharp, colicky pelvic pain associated with nausea, vomiting, bowel, and bladder symptoms is the usual presentation.\nsynonyms :Twisted fallopian tube\n'}


{'id': 'HP_0012885', 'url': 'http://purl.obolibrary.org/obo/HP_0012885', 'lbl': 'Fallopian tube duplication', 'desc': 'label: Fallopian tube duplication\ndefinition : The presence of a supernumerary Fallopian tube.\nsynonyms :Accessory fallopian tube\n'}


{'id': 'HP_0012886', 'url': 'http://purl.obolibrary.org/obo/HP_0012886', 'lbl': 'Hemorrhagic ovarian cyst', 'desc': 'label: Hemorrhagic ovarian cyst\ndefinition : An abdominal mass formed by bleeding into a follicular ovarian cyst or corpus luteum cyst.\nsynonyms :\n'}


{'id': 'HP_0012887', 'url': 'http://purl.obolibrary.org/obo/HP_0012887', 'lbl': 'Ovarian serous cystadenoma', 'desc': 'label: Ovarian serous cystadenoma\ndefinition : A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue.\nsynonyms :Serous ovarian cyst\n'}


{'id': 'HP_0012888', 'url': 'http://purl.obolibrary.org/obo/HP_0012888', 'lbl': 'Abnormal uterine cervix morphology', 'desc': 'label: Abnormal uterine cervix morphology\ndefinition : An anomaly of the neck of the uterus (lower part of the uterus), called the uterine cervix.\nsynonyms :Abnormality of the uterine cervix\n'}


{'id': 'HP_0012889', 'url': 'http://purl.obolibrary.org/obo/HP_0012889', 'lbl': 'Cervical endometriosis', 'desc': 'label: Cervical endometriosis\ndefinition : Abnormal growth of endometrial cells (which are normally limited to the uterus) within the cervix.\nsynonyms :\n'}


{'id': 'HP_0012890', 'url': 'http://purl.obolibrary.org/obo/HP_0012890', 'lbl': 'Posteriorly placed anus', 'desc': 'label: Posteriorly placed anus\ndefinition : Posterior malposition of the anus.\nsynonyms :\n'}


{'id': 'HP_0012891', 'url': 'http://purl.obolibrary.org/obo/HP_0012891', 'lbl': 'High posterior hairline', 'desc': 'label: High posterior hairline\ndefinition : Hair on the neck extends less inferiorly than usual.\nsynonyms :High hairline at back of head\n'}


{'id': 'HP_0012892', 'url': 'http://purl.obolibrary.org/obo/HP_0012892', 'lbl': 'Facial muscle hypertrophy', 'desc': 'label: Facial muscle hypertrophy\ndefinition : Hypertrophy of one or more muscles innervated by the facial nerve (the seventh cranial nerve).\nsynonyms :Increased size of facial muscles; Large facial muscles; Hyperplasia of facial muscles\n'}


{'id': 'HP_0012893', 'url': 'http://purl.obolibrary.org/obo/HP_0012893', 'lbl': 'Neck muscle hypertrophy', 'desc': 'label: Neck muscle hypertrophy\ndefinition : Muscle hypertrophy affecting the muscles of the neck.\nsynonyms :Increased size of neck muscles; Hypertrophy of cervical muscles; Large neck muscles; Overgrowth of neck muscles; Hyperplasia of neck muscles\n'}


{'id': 'HP_0012894', 'url': 'http://purl.obolibrary.org/obo/HP_0012894', 'lbl': 'Paraspinal muscle hypertrophy', 'desc': 'label: Paraspinal muscle hypertrophy\ndefinition : Muscle hypertrophy affecting the paraspinal muscles.\nsynonyms :\n'}


{'id': 'HP_0012895', 'url': 'http://purl.obolibrary.org/obo/HP_0012895', 'lbl': 'Scapular muscle hypertrophy', 'desc': 'label: Scapular muscle hypertrophy\ndefinition : Muscle hypertrophy affecting the scapular muscles.\nsynonyms :\n'}


{'id': 'HP_0012896', 'url': 'http://purl.obolibrary.org/obo/HP_0012896', 'lbl': 'Abnormal motor evoked potentials', 'desc': 'label: Abnormal motor evoked potentials\ndefinition : An anomaly identified by motor evoked potentials (MEPs). MEPs are measured following single-pulse or repetitive transcranial magnetic stimulation and can be used for the assessment of the excitability of the motor cortex and the integrity of conduction along the central and peripheral motor pathways.\nsynonyms :\n'}


{'id': 'HP_0012897', 'url': 'http://purl.obolibrary.org/obo/HP_0012897', 'lbl': 'Abnormal upper-limb motor evoked potentials', 'desc': 'label: Abnormal upper-limb motor evoked potentials\ndefinition : An anomaly identified by motor evoked potentials (MEPs) in the arm.\nsynonyms :Abnormal motor evoked potentials in the upper limb\n'}


{'id': 'HP_0012898', 'url': 'http://purl.obolibrary.org/obo/HP_0012898', 'lbl': 'Abnormal lower-limb motor evoked potentials', 'desc': 'label: Abnormal lower-limb motor evoked potentials\ndefinition : An anomaly identified by motor evoked potentials (MEPs) in the leg.\nsynonyms :Abnormal motor evoked potentials in the lower limb\n'}


{'id': 'HP_0012899', 'url': 'http://purl.obolibrary.org/obo/HP_0012899', 'lbl': 'Handgrip myotonia', 'desc': "label: Handgrip myotonia\ndefinition : Difficulty releasing one's grip associated with prolonged first handgrip relaxation times.\nsynonyms :Grip myotonia\n"}


{'id': 'HP_0012900', 'url': 'http://purl.obolibrary.org/obo/HP_0012900', 'lbl': 'Myotonia of the face', 'desc': 'label: Myotonia of the face\ndefinition : Slowed relaxation of muscles in the face.\nsynonyms :\n'}


{'id': 'HP_0012901', 'url': 'http://purl.obolibrary.org/obo/HP_0012901', 'lbl': 'Myotonia of the jaw', 'desc': 'label: Myotonia of the jaw\ndefinition : Slowed relaxation of muscles in the jaw.\nsynonyms :\n'}


{'id': 'HP_0012902', 'url': 'http://purl.obolibrary.org/obo/HP_0012902', 'lbl': 'Myotonia of the lower limb', 'desc': 'label: Myotonia of the lower limb\ndefinition : Slowed relaxation of muscles in the leg.\nsynonyms :\n'}


{'id': 'HP_0012903', 'url': 'http://purl.obolibrary.org/obo/HP_0012903', 'lbl': 'Myotonia of the upper limb', 'desc': 'label: Myotonia of the upper limb\ndefinition : Slowed relaxation of muscles in the arm.\nsynonyms :\n'}


{'id': 'HP_0012904', 'url': 'http://purl.obolibrary.org/obo/HP_0012904', 'lbl': 'Cold-sensitive myotonia', 'desc': 'label: Cold-sensitive myotonia\ndefinition : An involuntary and painless delay in the relaxation of skeletal muscle following contraction or electrical stimulation that is induced by exposure to cold.\nsynonyms :\n'}


{'id': 'HP_0012905', 'url': 'http://purl.obolibrary.org/obo/HP_0012905', 'lbl': 'Euryblepharon', 'desc': 'label: Euryblepharon\ndefinition : Euryblepharon is a congenital eyelid anomaly characterized by horizontal enlargement of the palpebral fissure. The eyelid is shortened vertically compared with the horizontal dimension, with associated lateral canthal malpositioning and lateral ectropion abnormally wide lid opening.\nsynonyms :Kabuki syndrome eyelids\n'}


{'id': 'HP_0020006', 'url': 'http://purl.obolibrary.org/obo/HP_0020006', 'lbl': 'Ciliary body coloboma', 'desc': 'label: Ciliary body coloboma\ndefinition : A coloboma of the ciliary body.\nsynonyms :\n'}


{'id': 'HP_0020034', 'url': 'http://purl.obolibrary.org/obo/HP_0020034', 'lbl': 'Diffuse', 'desc': 'label: Diffuse\ndefinition : A spatial pattern that is spread out, i.e., not localized.\nsynonyms :\n'}


{'id': 'HP_0020035', 'url': 'http://purl.obolibrary.org/obo/HP_0020035', 'lbl': 'Lower limb dysmetria', 'desc': 'label: Lower limb dysmetria\ndefinition : A lack of coordination of leg movement manifested by undershoot or overshoot of the intended position of the leg.\nsynonyms :\n'}


{'id': 'HP_0020036', 'url': 'http://purl.obolibrary.org/obo/HP_0020036', 'lbl': 'Upper limb dysmetria', 'desc': 'label: Upper limb dysmetria\ndefinition : A lack of coordination of arm movement manifested by undershoot or overshoot of the intended position of the arm.\nsynonyms :\n'}


{'id': 'HP_0020037', 'url': 'http://purl.obolibrary.org/obo/HP_0020037', 'lbl': 'Astasia', 'desc': 'label: Astasia\ndefinition : A postural abnormality characterized by the inability to stand without external support despite having sufficient muscle strength.\nsynonyms :\n'}


{'id': 'HP_0020038', 'url': 'http://purl.obolibrary.org/obo/HP_0020038', 'lbl': 'Vertebrobasilar dolichoectasia', 'desc': 'label: Vertebrobasilar dolichoectasia\ndefinition : Elongation, dilatation, and/or tortuosity of the vertebrobasilar segment. The definition of VBD includes: (i) diameter of basilar or vertebral artery over 4.5 mm; or (ii) deviation of any portion more than 10 mm from the shortest expected course; and (iii) length of basilar artery over 29.5 mm or length of intracranial vertebral artery over 23.5 mm.\nsynonyms :\n'}


{'id': 'HP_0020041', 'url': 'http://purl.obolibrary.org/obo/HP_0020041', 'lbl': 'Double elevator palsy', 'desc': 'label: Double elevator palsy\ndefinition : A type of incomitant strabismus in which both elevator muscles (i.e., the inferior oblique and superior rectus muscles) of the same eye are weak leading to restricted elevation and hypotropia.\nsynonyms :\n'}


{'id': 'HP_0020042', 'url': 'http://purl.obolibrary.org/obo/HP_0020042', 'lbl': 'Double depressor palsy', 'desc': 'label: Double depressor palsy\ndefinition : An ocular movement abnormality characterised by simultaneous weakness of the inferior rectus muscle and superior oblique muscle of the same eye.\nsynonyms :\n'}


{'id': 'HP_0020043', 'url': 'http://purl.obolibrary.org/obo/HP_0020043', 'lbl': 'Vertical incomitant strabismus', 'desc': "label: Vertical incomitant strabismus\ndefinition : A type of incomitant strabismus in which the angle of deviation varies as the patient's gaze shifts upwards and/or downwards.\nsynonyms :\n"}


{'id': 'HP_0020044', 'url': 'http://purl.obolibrary.org/obo/HP_0020044', 'lbl': 'Horizontal incomitant strabismus', 'desc': 'label: Horizontal incomitant strabismus\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0020045', 'url': 'http://purl.obolibrary.org/obo/HP_0020045', 'lbl': 'Esodeviation', 'desc': 'label: Esodeviation\ndefinition : A manifest or latent ocular deviation in which one or both eyes tends to deviate nasally.\nsynonyms :Convergent squint; Convergent strabismus\n'}


{'id': 'HP_0020046', 'url': 'http://purl.obolibrary.org/obo/HP_0020046', 'lbl': 'Accommodative esotropia', 'desc': 'label: Accommodative esotropia\ndefinition : A form of esotropia (convergent deviation of the eyes) associated with activation of the accommodative reflex.\nsynonyms :\n'}


{'id': 'HP_0020047', 'url': 'http://purl.obolibrary.org/obo/HP_0020047', 'lbl': 'Abnormal myeloid cell morphology', 'desc': 'label: Abnormal myeloid cell morphology\ndefinition : Any structural anomaly of a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.\nsynonyms :\n'}


{'id': 'HP_0020048', 'url': 'http://purl.obolibrary.org/obo/HP_0020048', 'lbl': 'Reduced bone-marrow pro-B cell count', 'desc': 'label: Reduced bone-marrow pro-B cell count\ndefinition : A reduction in the numbers of pro-B cells (defined by coexpression of CD34 and CD19). Earlier B-cell precursors are defined by expressing surface CD34 and cytoplasmic TdT in the absence of CD19.\nsynonyms :\n'}


{'id': 'HP_0020049', 'url': 'http://purl.obolibrary.org/obo/HP_0020049', 'lbl': 'Exodeviation', 'desc': 'label: Exodeviation\ndefinition : A manifest or latent ocular deviation in which one or both eyes tends to deviate temporally.\nsynonyms :Divergent strabismus\n'}


{'id': 'HP_0020050', 'url': 'http://purl.obolibrary.org/obo/HP_0020050', 'lbl': 'Anti-granulocyte-macrophage colony stimulating factor antibody positivity', 'desc': 'label: Anti-granulocyte-macrophage colony stimulating factor antibody positivity\ndefinition : The presence of autoantibodies in the serum that react against granulocyte-macrophage colony stimulating factor.\nsynonyms :Anti-GM-CSF antibody positivity\n'}


{'id': 'HP_0020054', 'url': 'http://purl.obolibrary.org/obo/HP_0020054', 'lbl': 'Abnormal erythrocyte physiology', 'desc': 'label: Abnormal erythrocyte physiology\ndefinition : Any functional abnormality of erythrocytes (red-blood cells).\nsynonyms :\n'}


{'id': 'HP_0020058', 'url': 'http://purl.obolibrary.org/obo/HP_0020058', 'lbl': 'Abnormal red blood cell count', 'desc': 'label: Abnormal red blood cell count\ndefinition : Any deviation from the normal number of red blood cells per volume in the circulation.\nsynonyms :Abnormal RBC count\n'}


{'id': 'HP_0020059', 'url': 'http://purl.obolibrary.org/obo/HP_0020059', 'lbl': 'Increased red blood cell count', 'desc': 'label: Increased red blood cell count\ndefinition : An abnormal elevation above the normal number of red blood cells per volume in the circulation.\nsynonyms :Increased RBC count\n'}


{'id': 'HP_0020060', 'url': 'http://purl.obolibrary.org/obo/HP_0020060', 'lbl': 'Decreased red blood cell count', 'desc': 'label: Decreased red blood cell count\ndefinition : An abnormal reduction below the normal number of red blood cells per volume in the circulation.\nsynonyms :Decreased RBC count\n'}


{'id': 'HP_0020061', 'url': 'http://purl.obolibrary.org/obo/HP_0020061', 'lbl': 'Abnormal hemoglobin concentration', 'desc': 'label: Abnormal hemoglobin concentration\ndefinition : Any deviation from the normal concentration of hemoglobin in the blood.\nsynonyms :Abnormal Hb concentration; Abnormal haemoglobin concentration\n'}


{'id': 'HP_0020062', 'url': 'http://purl.obolibrary.org/obo/HP_0020062', 'lbl': 'Decreased hemoglobin concentration', 'desc': 'label: Decreased hemoglobin concentration\ndefinition : An abnormal reduction below normal hemoglobin concentration in the circulation.\nsynonyms :Decreased Hb concentration; Decreased haemoglobin concentration\n'}


{'id': 'HP_0020063', 'url': 'http://purl.obolibrary.org/obo/HP_0020063', 'lbl': 'Increased hemoglobin concentration', 'desc': 'label: Increased hemoglobin concentration\ndefinition : An abnormal elevation above normal hemoglobin concentration in the circulation.\nsynonyms :Increased Hb concentration; Increased haemoglobin concentration\n'}


{'id': 'HP_0020064', 'url': 'http://purl.obolibrary.org/obo/HP_0020064', 'lbl': 'Abnormal eosinophil count', 'desc': 'label: Abnormal eosinophil count\ndefinition : Any deviation from the normal number of eosinophils per volume in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0020071', 'url': 'http://purl.obolibrary.org/obo/HP_0020071', 'lbl': 'Viremia', 'desc': 'label: Viremia\ndefinition : The presence of virus in the blood.\nsynonyms :\n'}


{'id': 'HP_0020072', 'url': 'http://purl.obolibrary.org/obo/HP_0020072', 'lbl': 'Persistent EBV viremia', 'desc': 'label: Persistent EBV viremia\ndefinition : Persistent presence of Epstein-Barr virus in the blood.\nsynonyms :\n'}


{'id': 'HP_0020073', 'url': 'http://purl.obolibrary.org/obo/HP_0020073', 'lbl': 'Hypopigmented macule', 'desc': 'label: Hypopigmented macule\ndefinition : A white or lighter patch of skin that may appear anywhere on the body and are caused by decreased skin pigmentation.\nsynonyms :\n'}


{'id': 'HP_0020074', 'url': 'http://purl.obolibrary.org/obo/HP_0020074', 'lbl': 'Crystalluria', 'desc': 'label: Crystalluria\ndefinition : The presence of crystals in the urine.\nsynonyms :\n'}


{'id': 'HP_0020075', 'url': 'http://purl.obolibrary.org/obo/HP_0020075', 'lbl': 'Leucine crystalluria', 'desc': 'label: Leucine crystalluria\ndefinition : The presence of leucine crystals in the urine.\nsynonyms :\n'}


{'id': 'HP_0020076', 'url': 'http://purl.obolibrary.org/obo/HP_0020076', 'lbl': 'Wrist ganglion', 'desc': 'label: Wrist ganglion\ndefinition : A benign soft tissue tumor of the wrist usually found in the dorsal aspect of the wrist and communicate with the joint via a pedicle. This pedicle usually originates not only at the scapholunate ligament, but also may arise from a number of other sites over the dorsal aspect of the wrist capsule.\nsynonyms :Ganglion cyst of the wrist\n'}


{'id': 'HP_0020077', 'url': 'http://purl.obolibrary.org/obo/HP_0020077', 'lbl': 'Carnitinuria', 'desc': 'label: Carnitinuria\ndefinition : An elevated level of carnitine in the urine.\nsynonyms :\n'}


{'id': 'HP_0020078', 'url': 'http://purl.obolibrary.org/obo/HP_0020078', 'lbl': 'Alaninuria', 'desc': 'label: Alaninuria\ndefinition : An increased level of alanine in the urine.\nsynonyms :Increased urinary alanine\n'}


{'id': 'HP_0020079', 'url': 'http://purl.obolibrary.org/obo/HP_0020079', 'lbl': 'Beta-alaninuria', 'desc': 'label: Beta-alaninuria\ndefinition : An increased level of beta-alanine in the urine.\nsynonyms :\n'}


{'id': 'HP_0020080', 'url': 'http://purl.obolibrary.org/obo/HP_0020080', 'lbl': 'Erythrocyte inclusion bodies', 'desc': 'label: Erythrocyte inclusion bodies\ndefinition : Nuclear or cytoplasmic aggregates of substances in red blood cells.\nsynonyms :\n'}


{'id': 'HP_0020081', 'url': 'http://purl.obolibrary.org/obo/HP_0020081', 'lbl': 'Pappenheimer bodies', 'desc': 'label: Pappenheimer bodies\ndefinition : A type of erythrocyte inclusion characterized by basophilic stippling of erythrocytes, that is, by numerous very small coarse or fine blue granules within the cytoplasm with the additional stipulation that the stippled particles are due to iron granules (demonstrable by the Prussian blue stain).\nsynonyms :\n'}


{'id': 'HP_0020082', 'url': 'http://purl.obolibrary.org/obo/HP_0020082', 'lbl': 'Heinz bodies', 'desc': 'label: Heinz bodies\ndefinition : A type of erythrocyte inclusion composed of denatured hemoglobin.\nsynonyms :\n'}


{'id': 'HP_0020083', 'url': 'http://purl.obolibrary.org/obo/HP_0020083', 'lbl': 'Furuncle', 'desc': 'label: Furuncle\ndefinition : An infection of a hair follicle that extends subcutaneously, forming an abscess.\nsynonyms :Boil\n'}


{'id': 'HP_0020084', 'url': 'http://purl.obolibrary.org/obo/HP_0020084', 'lbl': 'Carbuncle', 'desc': 'label: Carbuncle\ndefinition : A pustular lesion of the skin emerging from group of infected hair follicles, characterized by a deep location and dissecting through tissue planes. A carbuncle is larger and deeper than a furuncle.\nsynonyms :\n'}


{'id': 'HP_0020085', 'url': 'http://purl.obolibrary.org/obo/HP_0020085', 'lbl': 'Infection following live vaccination', 'desc': 'label: Infection following live vaccination\ndefinition : An infection resulting from live attenuated vaccines (LAV), that is, a vaccine prepared from living viruses or bacteria that have been weakened under laboratory conditions. LAV vaccines will replicate in a vaccinated individual and produce an immune response but usually cause mild or no disease. are derived from disease-causing pathogens.\nsynonyms :\n'}


{'id': 'HP_0020086', 'url': 'http://purl.obolibrary.org/obo/HP_0020086', 'lbl': 'BCGitis', 'desc': 'label: BCGitis\ndefinition : Local or regional infection with Bacillus Calmette-Guerin (BCG) following vaccination.\nsynonyms :\n'}


{'id': 'HP_0020087', 'url': 'http://purl.obolibrary.org/obo/HP_0020087', 'lbl': 'BCGosis', 'desc': 'label: BCGosis\ndefinition : Distant, or disseminated infection with Bacillus Calmette-Guerin (BCG) following vaccination associated with failure to contain thebacillus Calmette-Guerin (BCG) following vaccination leading to spread of BCG to many sites in the body. The tuberculosis vaccine BCG contains live attenuated Mycobacterium bovis.\nsynonyms :BCGiosis; Disseminated Bacillus Calmette-Guerin infection\n'}


{'id': 'HP_0020088', 'url': 'http://purl.obolibrary.org/obo/HP_0020088', 'lbl': 'Post-vaccination measles', 'desc': 'label: Post-vaccination measles\ndefinition : Infection with the measles virus of the live-attenuated vaccine. This is an extremely rare event and may indicate immunocompromise in some cases.\nsynonyms :Vaccine associated measles\n'}


{'id': 'HP_0020089', 'url': 'http://purl.obolibrary.org/obo/HP_0020089', 'lbl': 'Post-vaccination rubella', 'desc': 'label: Post-vaccination rubella\ndefinition : Infection with the rubella virus of the live-attenuated vaccine.\nsynonyms :\n'}


{'id': 'HP_0020090', 'url': 'http://purl.obolibrary.org/obo/HP_0020090', 'lbl': 'Post-vaccination polio', 'desc': 'label: Post-vaccination polio\ndefinition : Infection with live attenuated polio vaccine following vaccination. This is an extreemely rare event that may indicate immunocompromise.\nsynonyms :\n'}


{'id': 'HP_0020091', 'url': 'http://purl.obolibrary.org/obo/HP_0020091', 'lbl': 'Post-vaccination rotavirus infection', 'desc': 'label: Post-vaccination rotavirus infection\ndefinition : Infection with live attenuated rotavirus vaccine following vaccination.\nsynonyms :\n'}


{'id': 'HP_0020093', 'url': 'http://purl.obolibrary.org/obo/HP_0020093', 'lbl': 'Recurrent deep organ abscess formation', 'desc': 'label: Recurrent deep organ abscess formation\ndefinition : Repeated episodes of the formation of abscesses in organs. An abscess is a circumscribed area of pus or necrotic debris in the parenchyma or an organ.\nsynonyms :\n'}


{'id': 'HP_0020095', 'url': 'http://purl.obolibrary.org/obo/HP_0020095', 'lbl': 'Prolonged need of intravenous antibiotic therapy', 'desc': 'label: Prolonged need of intravenous antibiotic therapy\ndefinition : Clinical assessment of a requirement to treat with intravenous antibiotics over an unusually prolonged period of time.\nsynonyms :\n'}


{'id': 'HP_0020096', 'url': 'http://purl.obolibrary.org/obo/HP_0020096', 'lbl': 'Recurrent streptococcal infections', 'desc': 'label: Recurrent streptococcal infections\ndefinition : Increased susceptibility to streptococcal infections, as manifested by recurrent episodes of streptococcal infections.\nsynonyms :\n'}


{'id': 'HP_0020097', 'url': 'http://purl.obolibrary.org/obo/HP_0020097', 'lbl': 'Infection due to encapsulated bacteria', 'desc': 'label: Infection due to encapsulated bacteria\ndefinition : An infection by an encapsulated bacterial agent. Isolates which cause invasive disease are usually surrounded by a polysaccharide capsule, which is a major virulence factor and the key antigen in protective protein-polysaccharide conjugate vaccines.\nsynonyms :\n'}


{'id': 'HP_0020098', 'url': 'http://purl.obolibrary.org/obo/HP_0020098', 'lbl': 'obsolete Herpes encephalitis', 'desc': 'label: obsolete Herpes encephalitis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0020099', 'url': 'http://purl.obolibrary.org/obo/HP_0020099', 'lbl': 'Severe norovirus infection', 'desc': 'label: Severe norovirus infection\ndefinition : An unusually severe course of infection with Human norovirus, previously known as Norwalk virus. Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen. Norovirus infection-associated illness may also be more prolonged and severe in immunocompromised individuals and may be associated with remarkably persistent viral excretion in some of these individuals.\nsynonyms :\n'}


{'id': 'HP_0020100', 'url': 'http://purl.obolibrary.org/obo/HP_0020100', 'lbl': 'Unusual fungal infection', 'desc': 'label: Unusual fungal infection\ndefinition : An unusual fungal infection that is regarded as a sign of a pathological susceptibility to infection by a fungal agent.\nsynonyms :\n'}


{'id': 'HP_0020101', 'url': 'http://purl.obolibrary.org/obo/HP_0020101', 'lbl': 'Invasive fungal infection', 'desc': 'label: Invasive fungal infection\ndefinition : Fungal infection characterized by invasion of host tissues.\nsynonyms :\n'}


{'id': 'HP_0020102', 'url': 'http://purl.obolibrary.org/obo/HP_0020102', 'lbl': 'Pneumocystis jirovecii pneumonia', 'desc': 'label: Pneumocystis jirovecii pneumonia\ndefinition : An opportunistic disease caused by invasion of unicellular fungus Pneumocystis jirovecii. Transmission of P. jirovecii cysts takes place through the airborne route, and usually, its presence in lungs is asymptomatic. However, people with impaired immunity, especially those with CD4+ T cell count below 200/microliter, are still at risk of the development of Pneumocystis pneumonia due to P. jirovecii invasion. Symptoms induced by this disease are not specific: progressive dyspnoea, non-productive cough, low-grade fever, arterial partial pressure of oxygen below 65 mmHg, and chest radiographs demonstrating bilateral, interstitial shadowing.\nsynonyms :\n'}


{'id': 'HP_0020103', 'url': 'http://purl.obolibrary.org/obo/HP_0020103', 'lbl': 'Invasive pulmonary aspergillosis', 'desc': 'label: Invasive pulmonary aspergillosis\ndefinition : Infection of the lungs with aspergillus. In the respiratory mucosa, the spores may germinate into hyphae, which in turn can invade the mucosa leading to invasive pulmonary aspergillosis.\nsynonyms :\n'}


{'id': 'HP_0020104', 'url': 'http://purl.obolibrary.org/obo/HP_0020104', 'lbl': 'Unusual protozoan infection', 'desc': 'label: Unusual protozoan infection\ndefinition : An unusual protozoan infection that is regarded as a sign of a pathological susceptibility to infection by a protozoal agent.\nsynonyms :\n'}


{'id': 'HP_0020105', 'url': 'http://purl.obolibrary.org/obo/HP_0020105', 'lbl': 'Severe toxoplasmosis', 'desc': 'label: Severe toxoplasmosis\ndefinition : Toxoplasmosis is a widespread parasitic infection that is frequently asymptomatic in immunocompetent patients. However, this obligate intracellular protozoan parasite can evade the immune system and persist for the life of its host in cyst form, predominantly in the brain, retina, and muscles. Reactivation of latent cysts may occur when the immune system fails to maintain cytokine pressure, which mainly relies on gamma interferon (IFN-gamma). Toxoplasmosis is a life-threatening infection in immunocompromised patients (ICPs).\nsynonyms :\n'}


{'id': 'HP_0020106', 'url': 'http://purl.obolibrary.org/obo/HP_0020106', 'lbl': 'Severe giardiasis', 'desc': 'label: Severe giardiasis\ndefinition : An unusually severe infection due to Giardia lamblia, also called Giardia duodenalis or Giardia intestinalis, which is a protozoan parasite of the small intestine that causes extensive morbidity worldwide.\nsynonyms :\n'}


{'id': 'HP_0020107', 'url': 'http://purl.obolibrary.org/obo/HP_0020107', 'lbl': 'Unusual helminthic infection', 'desc': 'label: Unusual helminthic infection\ndefinition : An unusual helminthic infection that is regarded as a sign of a pathological susceptibility to infection by a worm (helminth).\nsynonyms :\n'}


{'id': 'HP_0020108', 'url': 'http://purl.obolibrary.org/obo/HP_0020108', 'lbl': 'Unusual parasitic infection', 'desc': 'label: Unusual parasitic infection\ndefinition : An unusual parasitic infection that is regarded as a sign of a pathological susceptibility to infection by a parasite.\nsynonyms :\n'}


{'id': 'HP_0020110', 'url': 'http://purl.obolibrary.org/obo/HP_0020110', 'lbl': 'Bone fracture', 'desc': 'label: Bone fracture\ndefinition : A partial or complete breakage of the continuity of a bone.\nsynonyms :\n'}


{'id': 'HP_0020111', 'url': 'http://purl.obolibrary.org/obo/HP_0020111', 'lbl': 'Abnormal CD4+CD25+ regulatory T cell proportion', 'desc': 'label: Abnormal CD4+CD25+ regulatory T cell proportion\ndefinition : A deviation from the normal proportion of CD4-positive, CD25-positive, alpha-beta regulatory T cells in circulation, relative to another population of cells.\nsynonyms :Abnormal CD4+CD25+ Treg cell proportion\n'}


{'id': 'HP_0020112', 'url': 'http://purl.obolibrary.org/obo/HP_0020112', 'lbl': 'Increased proportion of CD4+CD25+ regulatory T cells', 'desc': 'label: Increased proportion of CD4+CD25+ regulatory T cells\ndefinition : An abnormally increased proportion of CD4-positive, CD25-positive, alpha-beta regulatory T cells in circulation, relative to another population of cells.\nsynonyms :Elevated proportion of CD4+CD25+ regulatory T cells; Increased proportion of CD4+CD25+ Treg cells\n'}


{'id': 'HP_0020113', 'url': 'http://purl.obolibrary.org/obo/HP_0020113', 'lbl': 'Decreased proportion of CD4+CD25+ regulatory T cells', 'desc': 'label: Decreased proportion of CD4+CD25+ regulatory T cells\ndefinition : An abnormally decreased proportion of CD4-positive, CD25-positive, alpha-beta regulatory T cells in circulation, relative to another population of cells.\nsynonyms :Decreased proportion of CD4+CD25+ Treg cells; Reduced proportion of CD4+CD25+ regulatory T cells\n'}


{'id': 'HP_0020114', 'url': 'http://purl.obolibrary.org/obo/HP_0020114', 'lbl': 'Persistent human papillomavirus infection', 'desc': 'label: Persistent human papillomavirus infection\ndefinition : Human papillomaviruses (HPVs) are small oncogenic viruses. HPV has been shown to cause a variety of lesions and malignancies, which predominantly affect the anogenital region. Low-risk, non-oncogenic HPV types are associated with anogenital warts and recurrent respiratory papillomatosis while high-risk, oncogenic types are associated with cervical, penile, anal, vaginal, vulvar, and oropharyngeal cancers. Infection with anogenital HPV is usually asymptomatic and resolves spontaneously without consequences in the immunocompetent host. When disease does occur, the most common manifestation is genital warts, which may be small papules, or flat, smooth or pedunculated lesions. This resolution of HPV lesions is not generally seen in the immunosuppressed, resulting in severe, persistent and extensive manifestations of HPV disease.\nsynonyms :\n'}


{'id': 'HP_0020117', 'url': 'http://purl.obolibrary.org/obo/HP_0020117', 'lbl': 'Hypoplastic dermoepidermal hemidesmosomes', 'desc': 'label: Hypoplastic dermoepidermal hemidesmosomes\ndefinition : Underdeveloped hemidesmosomes at the dermoepidermal junction. Hemidesmosomes are the specialized junctional complexes, that contribute to the attachment of epithelial cells to the underlying basement membrane in stratified and other complex epithelia, such as the skin.\nsynonyms :\n'}


{'id': 'HP_0020118', 'url': 'http://purl.obolibrary.org/obo/HP_0020118', 'lbl': 'Radial artery aplasia', 'desc': 'label: Radial artery aplasia\ndefinition : Congenital absence of the radial artery.\nsynonyms :\n'}


{'id': 'HP_0020119', 'url': 'http://purl.obolibrary.org/obo/HP_0020119', 'lbl': 'Abnormal retinal nerve fiber layer morphology', 'desc': 'label: Abnormal retinal nerve fiber layer morphology\ndefinition : A structural abnormality of the retinal nerve fiber layer\nsynonyms :Abnormal retinal nerve fibre layer morphology\n'}


{'id': 'HP_0020120', 'url': 'http://purl.obolibrary.org/obo/HP_0020120', 'lbl': 'Retinal nerve fiber edema', 'desc': 'label: Retinal nerve fiber edema\ndefinition : Swelling (edema) of the retinal nerve fibers.\nsynonyms :Retinal nerve fibre oedema\n'}