{'id': 'HP_0033943', 'url': 'http://purl.obolibrary.org/obo/HP_0033943', 'lbl': 'Arcuate vein medial/intimal coagulative necrosis', 'desc': 'label: Arcuate vein medial/intimal coagulative necrosis\ndefinition : A type of arcuate vein medial/intimal necrosis in which the dead (necrotic) tissue retains the outlines of the dead structures.\nsynonyms :Coagulative necrosis within arcuate vein intima/media\n'}


{'id': 'HP_0033944', 'url': 'http://purl.obolibrary.org/obo/HP_0033944', 'lbl': 'Arcuate vein medial/intimal liquefactive necrosis', 'desc': 'label: Arcuate vein medial/intimal liquefactive necrosis\ndefinition : A type of arcuate vein medial/intimal necrosis in which the dead (necrotic) tissue breaks down such that cellular detail is no longer recognized.\nsynonyms :Liquefactive necrosis within arcuate vein intima/media\n'}


{'id': 'HP_0033945', 'url': 'http://purl.obolibrary.org/obo/HP_0033945', 'lbl': 'Arcuate intimal/medial granulomatous venulitis', 'desc': 'label: Arcuate intimal/medial granulomatous venulitis\ndefinition : A type of arcuate intimal/medial venulitis characterized by circumscribed inflammatory lesions comprised primarily of macrophages present in inflamed veins.\nsynonyms :\n'}


{'id': 'HP_0033946', 'url': 'http://purl.obolibrary.org/obo/HP_0033946', 'lbl': 'Arcuate vein intima/media crystal accumulation', 'desc': 'label: Arcuate vein intima/media crystal accumulation\ndefinition : Deposition of crystals such as uric acid, oxalate, or cystine in the inner or middle layer of the arcuate veins of the kidney.\nsynonyms :\n'}


{'id': 'HP_0033947', 'url': 'http://purl.obolibrary.org/obo/HP_0033947', 'lbl': 'Renal arteriole intima/media crystal accumulation', 'desc': 'label: Renal arteriole intima/media crystal accumulation\ndefinition : Deposition of crystals such as uric acid, oxalate, or cystine in the inner or middle layer of the arterioles of the kidney.\nsynonyms :Accumulated crystals within renal arteriolar intima/media\n'}


{'id': 'HP_0033948', 'url': 'http://purl.obolibrary.org/obo/HP_0033948', 'lbl': 'Arcuate artery intima/media arteriitis', 'desc': 'label: Arcuate artery intima/media arteriitis\ndefinition : Inflammation of the inner or middle layer of the arcuate arteries of the kidney.\nsynonyms :Arteritis within arcuate arterial intima/media\n'}


{'id': 'HP_0033949', 'url': 'http://purl.obolibrary.org/obo/HP_0033949', 'lbl': 'Arcuate artery intima/media granulomatous arteriitis', 'desc': 'label: Arcuate artery intima/media granulomatous arteriitis\ndefinition : A type of arcuate artery intima/media granulomatous arteriitis characterized by circumscribed inflammatory lesions comprised primarily of macrophages present in inflamed arteries.\nsynonyms :Granulomatous arteritis within arcuate arterial intima/media\n'}


{'id': 'HP_0033950', 'url': 'http://purl.obolibrary.org/obo/HP_0033950', 'lbl': 'Cortical radial artery intraluminal thrombi', 'desc': 'label: Cortical radial artery intraluminal thrombi\ndefinition : Mixture of fibrin, red blood cells, platelets partly or completely occluding vascular lumen within the interior space of cortical radial arteries (interlobular arteries) of the kidney.\nsynonyms :Intraluminal thrombi within interlobular arterial lumen\n'}


{'id': 'HP_0033951', 'url': 'http://purl.obolibrary.org/obo/HP_0033951', 'lbl': 'Cortical radial artery intraluminal organized thrombi', 'desc': 'label: Cortical radial artery intraluminal organized thrombi\ndefinition : Thrombi containing fibrous tissue and capillary-like vascular channels within the interior space of cortical radial arteries (interlobular arteries) of the kidney.\nsynonyms :Organized thrombi within interlobular arterial lumen\n'}


{'id': 'HP_0033952', 'url': 'http://purl.obolibrary.org/obo/HP_0033952', 'lbl': 'Abnormal cortical radial artery endothelium morphology', 'desc': 'label: Abnormal cortical radial artery endothelium morphology\ndefinition : Abnormal structural characteristics of the lining (endothelium) of the cortical radial arteries (also known as interlobular arteries) of the kidney.\nsynonyms :Abnormalities of the interlobular arterial endothelium\n'}


{'id': 'HP_0033953', 'url': 'http://purl.obolibrary.org/obo/HP_0033953', 'lbl': 'Cortical radial artery endotheliosis', 'desc': 'label: Cortical radial artery endotheliosis\ndefinition : Enlargement of endothelial cells of the cortical radial arteries (also known as the interlobular arteries) of the kidney because of cytoplasmic swelling.\nsynonyms :Endotheliosis within interlobular arteries\n'}


{'id': 'HP_0033954', 'url': 'http://purl.obolibrary.org/obo/HP_0033954', 'lbl': 'Cortical radial artery hypercellularity', 'desc': 'label: Cortical radial artery hypercellularity\ndefinition : Proliferation of endothelial cells (increased number of cells) of the lining (endothelium) of the cortical radial arteries (also known as interlobular arteries) of the kidney.\nsynonyms :Endoarterial hypercellularity within interlobular artery\n'}


{'id': 'HP_0033955', 'url': 'http://purl.obolibrary.org/obo/HP_0033955', 'lbl': 'Cortical radial artery leukocyte hypercellularity', 'desc': 'label: Cortical radial artery leukocyte hypercellularity\ndefinition : A type of cortical radial artery endoarterial hypercellularity due to increased numbers of white blood cells (leukocytes).\nsynonyms :Endoarterial hypercellularity within interlobular artery consisting of leukocytes\n'}


{'id': 'HP_0033956', 'url': 'http://purl.obolibrary.org/obo/HP_0033956', 'lbl': 'Cortical radial artery lymphocyte hypercellularity', 'desc': 'label: Cortical radial artery lymphocyte hypercellularity\ndefinition : A type of cortical radial artery endoarterial leukocyte hypercellularity due to the presence of increased number of lymphocytes in the lumen of cortical radial arteries.\nsynonyms :Endoarterial hypercellularity within interlobular artery consisting of lymphocytes\n'}


{'id': 'HP_0033957', 'url': 'http://purl.obolibrary.org/obo/HP_0033957', 'lbl': 'Cortical radial artery neutrophil hypercellularity', 'desc': 'label: Cortical radial artery neutrophil hypercellularity\ndefinition : A type of cortical radial artery endoarterial leukocyte hypercellularity due to the presence of increased numbers of neutrophils in the lumen of cortical radial arteries.\nsynonyms :Endocapillary hypercellularity within interlobular arterial endothelium consisting of neutrophils\n'}


{'id': 'HP_0033958', 'url': 'http://purl.obolibrary.org/obo/HP_0033958', 'lbl': 'Cortical radial artery foam cell hypercellularity', 'desc': 'label: Cortical radial artery foam cell hypercellularity\ndefinition : A type of cortical radial artery endoarterial leukocyte hypercellularity due to the presence of lipid-filled cells, often macrophages, with a vacuolated appearance in the lumen of cortical radial artery (also known as the interlobular artery) of the kidney.\nsynonyms :Endocapillary hypercellularity within interlobular arterial endothelium consisting of foam cells\n'}


{'id': 'HP_0033959', 'url': 'http://purl.obolibrary.org/obo/HP_0033959', 'lbl': 'Cortical radial artery intima/media arteriosclerosis', 'desc': 'label: Cortical radial artery intima/media arteriosclerosis\ndefinition : Thickening of the intima of the cortical radial artery (also known as the interlobular artery) of the kidney characterized by fibrosis and/or duplication of the elastic lamina.\nsynonyms :Arteriosclerosis within interlobular arterial intima/media\n'}


{'id': 'HP_0033960', 'url': 'http://purl.obolibrary.org/obo/HP_0033960', 'lbl': 'Cortical radial artery intimal mucoid edema', 'desc': 'label: Cortical radial artery intimal mucoid edema\ndefinition : Accumulation of edematous extracellular matrix in the intima of the cortical radial artery (also known as the interlobular artery) of the kidney. This material resembles mucus and stains pale blue on hematoxylin and eosin staining.\nsynonyms :Intimal mucoid edema within interlobular arterial intima/media\n'}


{'id': 'HP_0033961', 'url': 'http://purl.obolibrary.org/obo/HP_0033961', 'lbl': 'Cortical radial artery intima/media multilamellation', 'desc': 'label: Cortical radial artery intima/media multilamellation\ndefinition : Myointimal hyperplasia of the inner and middle layer of the cortical radial artery (also known as the interlobular artery) of the kidney, arranged in multiple concentric layers.\nsynonyms :Cortical radial artery intima/media onion skinning; Multilamellation (onion skinning) within interlobular arterial intima/media\n'}


{'id': 'HP_0033962', 'url': 'http://purl.obolibrary.org/obo/HP_0033962', 'lbl': 'Cortical radial artery medial/intimal granulomatous arteriitis', 'desc': 'label: Cortical radial artery medial/intimal granulomatous arteriitis\ndefinition : A type of cortical radial artery medial/intimal arteriitis that is characterized by circumscribed inflammatory lesions comprised primarily of macrophages present in inflamed arteries.\nsynonyms :\n'}


{'id': 'HP_0033963', 'url': 'http://purl.obolibrary.org/obo/HP_0033963', 'lbl': 'Abnormal interlobular vein intima/media morphology', 'desc': 'label: Abnormal interlobular vein intima/media morphology\ndefinition : Any structural anomaly of the inner or middle layer of the interlobular veins of the kidney.\nsynonyms :\n'}


{'id': 'HP_0033964', 'url': 'http://purl.obolibrary.org/obo/HP_0033964', 'lbl': 'Interlobular intima/media venosclerosis', 'desc': 'label: Interlobular intima/media venosclerosis\ndefinition : Thickening of the intima with fibrosis and/or duplication of the elastic lamina in interlobular veins of the kidney.\nsynonyms :Venosclerosis within interlobular vein intima/media\n'}


{'id': 'HP_0033965', 'url': 'http://purl.obolibrary.org/obo/HP_0033965', 'lbl': 'Interlobular vein intimal mucoid edema', 'desc': 'label: Interlobular vein intimal mucoid edema\ndefinition : Accumulation of edematous extracellular matrix in the intima of the interlobular vein of the kidney. This material resembles mucus and stains pale blue on hematoxylin and eosin staining.\nsynonyms :Intimal mucoid edema within interlobular veins\n'}


{'id': 'HP_0033966', 'url': 'http://purl.obolibrary.org/obo/HP_0033966', 'lbl': 'Interlobular vein intima/media amyloidosis', 'desc': 'label: Interlobular vein intima/media amyloidosis\ndefinition : Amorphous extracellular substance in the glomerular, interstitial or vascular compartments of the interlobular veins of the kidney. Congo-red positive with typically an apple green birerfingence on polarization microscopy, and 8-12 nm fibrils on electron microscopy\nsynonyms :Amyloidosis within interlobular vein intima/media\n'}


{'id': 'HP_0033967', 'url': 'http://purl.obolibrary.org/obo/HP_0033967', 'lbl': 'Interlobular vein intima/media venulitis', 'desc': 'label: Interlobular vein intima/media venulitis\ndefinition : Inflammation of the interlobular veins of the kidney which may affect only the intima or may be transmural.\nsynonyms :Venulitis within interlobular vein intima/media\n'}


{'id': 'HP_0033968', 'url': 'http://purl.obolibrary.org/obo/HP_0033968', 'lbl': 'Interlobular vein intima/media granulomatous venulitis', 'desc': 'label: Interlobular vein intima/media granulomatous venulitis\ndefinition : A type of interlobular vein intima/media venulitis that is characterized by circumscribed inflammatory lesions comprised primarily of macrophages present in inflamed veins.\nsynonyms :Granulomatous venulitis within interlobular vein intima/media\n'}


{'id': 'HP_0033969', 'url': 'http://purl.obolibrary.org/obo/HP_0033969', 'lbl': 'Interlobular vein intima/media necrosis', 'desc': 'label: Interlobular vein intima/media necrosis\ndefinition : Cell death (necrosis) in the inner or middle layer of the interlobular vein of the kidney.\nsynonyms :Necrosis within interlobular vein intima/media\n'}


{'id': 'HP_0033970', 'url': 'http://purl.obolibrary.org/obo/HP_0033970', 'lbl': 'Interlobular vein intima/media liquefactive necrosis', 'desc': 'label: Interlobular vein intima/media liquefactive necrosis\ndefinition : A type of interlobular vein intima/media necrosis in which the dead (necrotic) tissue breaks down such that cellular detail is no longer recognized.\nsynonyms :Liquefactive necrosis within interlobular vein intima/media\n'}


{'id': 'HP_0033971', 'url': 'http://purl.obolibrary.org/obo/HP_0033971', 'lbl': 'Interlobular vein intima/media coagulative necrosis', 'desc': 'label: Interlobular vein intima/media coagulative necrosis\ndefinition : A type of interlobular vein intima/media necrosis in which the dead (necrotic) tissue retains the outlines of the dead structures.\nsynonyms :\n'}


{'id': 'HP_0033972', 'url': 'http://purl.obolibrary.org/obo/HP_0033972', 'lbl': 'Interlobular vein medial atrophy', 'desc': 'label: Interlobular vein medial atrophy\ndefinition : Atrophy (wasting, decreased thickness) of the medial layer pf the interlobular veins of the kidney.\nsynonyms :Medial atrophy within interlobular veins\n'}


{'id': 'HP_0033973', 'url': 'http://purl.obolibrary.org/obo/HP_0033973', 'lbl': 'Interlobular vein medial hypertrophy', 'desc': 'label: Interlobular vein medial hypertrophy\ndefinition : Increased thickness of middle layer of the interlobular veins of the kidney.\nsynonyms :Medial hypertrophy within interlobular veins\n'}


{'id': 'HP_0033974', 'url': 'http://purl.obolibrary.org/obo/HP_0033974', 'lbl': 'Interlobular vein intima/media multilamellation', 'desc': 'label: Interlobular vein intima/media multilamellation\ndefinition : Myointimal hyperplasia of the inner and middle layer of the interlobular veins of the kidney, arranged in multiple concentric layers.\nsynonyms :Interlobular vein intima/media onion skinning; Multilamellation (onion skinning) within interlobular vein intima/media\n'}


{'id': 'HP_0033975', 'url': 'http://purl.obolibrary.org/obo/HP_0033975', 'lbl': 'Absent second fingernail', 'desc': 'label: Absent second fingernail\ndefinition : Absence of the fingernail of the index (second) finger.\nsynonyms :\n'}


{'id': 'HP_0033976', 'url': 'http://purl.obolibrary.org/obo/HP_0033976', 'lbl': 'Volar fingernail', 'desc': 'label: Volar fingernail\ndefinition : The presence of an extra nail on the palmar (volar, ventral) surface of the finger.\nsynonyms :Palmar fingernail; Ventral fingernail\n'}


{'id': 'HP_0033977', 'url': 'http://purl.obolibrary.org/obo/HP_0033977', 'lbl': 'Talar aplasia', 'desc': 'label: Talar aplasia\ndefinition : Absent talus owing to a congenital defect.\nsynonyms :Absent talus; Talus aplasia\n'}


{'id': 'HP_0033978', 'url': 'http://purl.obolibrary.org/obo/HP_0033978', 'lbl': 'Reduced beta-hexosaminidase activity', 'desc': 'label: Reduced beta-hexosaminidase activity\ndefinition : Diminished activity of the enzyme beta-hexosaminidase in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0033979', 'url': 'http://purl.obolibrary.org/obo/HP_0033979', 'lbl': 'Excessive dynamic airway collapse', 'desc': 'label: Excessive dynamic airway collapse\ndefinition : Excessive anterior displacement of the tracheal and/or bronchial membranous wall.\nsynonyms :Membranous tracheobronchomalacia\n'}


{'id': 'HP_0033980', 'url': 'http://purl.obolibrary.org/obo/HP_0033980', 'lbl': 'Paroxysmal tonic upgaze', 'desc': 'label: Paroxysmal tonic upgaze\ndefinition : Recurrent episodes of sustained upward deviation of the eyes and incomplete downward saccades, and normal horizontal eye movements without impairment of consciousness.\nsynonyms :\n'}


{'id': 'HP_0033981', 'url': 'http://purl.obolibrary.org/obo/HP_0033981', 'lbl': 'Vertebral artery tortuosity', 'desc': 'label: Vertebral artery tortuosity\ndefinition : Abnormal tortuous (i.e., twisted) form of the vertebral arteries.\nsynonyms :Tortuous vertebral arteries\n'}


{'id': 'HP_0033982', 'url': 'http://purl.obolibrary.org/obo/HP_0033982', 'lbl': 'Celiac artery dissection', 'desc': 'label: Celiac artery dissection\ndefinition : A separation (dissection) of the layers of the celiac artery wall.\nsynonyms :\n'}


{'id': 'HP_0033983', 'url': 'http://purl.obolibrary.org/obo/HP_0033983', 'lbl': 'Decreased circulating apolipoprotein C-II concentration', 'desc': 'label: Decreased circulating apolipoprotein C-II concentration\ndefinition : Reduced concentration of apolipoprotein C-II in the blood circulation.\nsynonyms :Decreased plasma apolipoprotein C-II\n'}


{'id': 'HP_0033984', 'url': 'http://purl.obolibrary.org/obo/HP_0033984', 'lbl': 'Increased urinary 8-oxo-7,8-dihydroguanosine level', 'desc': 'label: Increased urinary 8-oxo-7,8-dihydroguanosine level\ndefinition : An elevated amount of 8-oxo-7,8-dihydroguanosine in the urine.\nsynonyms :Increased urinary 8-oxo-7,8-dihydroguanosine; Increased urinary 8-oxo-Gsn level; Increased urine 8-oxo-7,8-dihydroguanosine; Increased urine 8-oxo-GMP\n'}


{'id': 'HP_0033985', 'url': 'http://purl.obolibrary.org/obo/HP_0033985', 'lbl': 'Elongated femoral neck', 'desc': 'label: Elongated femoral neck\ndefinition : Increased length of the neck of the femur.\nsynonyms :Long femoral neck\n'}


{'id': 'HP_0033986', 'url': 'http://purl.obolibrary.org/obo/HP_0033986', 'lbl': 'Tortuous lymphatic vessels', 'desc': 'label: Tortuous lymphatic vessels\ndefinition : The presence of an increased number of twists and turns of lymphatic vessels.\nsynonyms :Tortuous lymphatics\n'}


{'id': 'HP_0033987', 'url': 'http://purl.obolibrary.org/obo/HP_0033987', 'lbl': 'Phosphaturic mesenchymal tumor', 'desc': 'label: Phosphaturic mesenchymal tumor\ndefinition : A rare, endocrine active tumor that causes severe renal phosphate wasting, which in turn can lead to critical osteomalacia. Phosphaturic mesenchymal tumors (PMTs) are typically small and mostly benign tumors producing fibroblast growth factor 23 (FGF-23). FGF-23 lowers the expression of sodium/phosphate cotransporters, which are the primary transport proteins responsible for phosphate reabsorption in the kidneys. The paraneoplastic overproduction of FGF-23 lowers reabsorption of phosphate and causes severe paraneoplastic renal phosphate wasting and hypophosphatemia. FGF-23 also affects vitamin D levels by lowering 25-hydroxyvitamin D 1-alpha-hydroxylase in the proximal renal tubules and by increasing the expression of vitamin D 24-hydroxylase, a mitochondrial enzyme responsible for inactivating vitamin D metabolites.\nsynonyms :\n'}


{'id': 'HP_0033988', 'url': 'http://purl.obolibrary.org/obo/HP_0033988', 'lbl': 'Amygdala microinfarct', 'desc': 'label: Amygdala microinfarct\ndefinition : An infarct located in the almond-shaped body of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe that can only be observed microscopically.\nsynonyms :\n'}


{'id': 'HP_0033989', 'url': 'http://purl.obolibrary.org/obo/HP_0033989', 'lbl': 'Hippocampal microinfarct', 'desc': 'label: Hippocampal microinfarct\ndefinition : An infarct located in the structure of the cerebrum involved with memory storage and spatial navigation that can only be observed microscopically.\nsynonyms :\n'}


{'id': 'HP_0033990', 'url': 'http://purl.obolibrary.org/obo/HP_0033990', 'lbl': 'Cartilaginous tracheobronchomalacia', 'desc': 'label: Cartilaginous tracheobronchomalacia\ndefinition : Softening of the tracheal and/or bronchial cartilage resulting in segmental tracheal and/or bronchial weakness.\nsynonyms :Cartilaginous malacia\n'}


{'id': 'HP_0033991', 'url': 'http://purl.obolibrary.org/obo/HP_0033991', 'lbl': 'Vasa previa', 'desc': 'label: Vasa previa\ndefinition : Vasa previa occurs when the membranes that contain the umbilical cord traverse the membranes overlying the internal os of the cervix. There is a high risk of fetal mortality if not identified perinatally.\nsynonyms :\n'}


{'id': 'HP_0033992', 'url': 'http://purl.obolibrary.org/obo/HP_0033992', 'lbl': 'Chronotropic incompetence', 'desc': 'label: Chronotropic incompetence\ndefinition : Inability of the heart to increase its rate commensurate with increased activity or demand.\nsynonyms :\n'}


{'id': 'HP_0033993', 'url': 'http://purl.obolibrary.org/obo/HP_0033993', 'lbl': 'Viral encephalitis', 'desc': 'label: Viral encephalitis\ndefinition : An inflammation of brain parenchyma due to infection with a virus. Viral encephalitis can occur as a rare complication of common infections (eg, herpes virus infections) or can occur as a characteristic presentation of rare viruses (eg, rabies virus infection). Encephalitis may be the only neurologic manifestation of infection, or may occur in association with meningitis, myelitis, radiculitis, or neuritis. Viral encephalitis is associated with neurological dysfunction.\nsynonyms :\n'}


{'id': 'HP_0033994', 'url': 'http://purl.obolibrary.org/obo/HP_0033994', 'lbl': 'Dependency on parenteral nutrition', 'desc': 'label: Dependency on parenteral nutrition\ndefinition : Inability to ingest sufficient quantities of nutrition by mouth or by tube-feeding with the corresponding requirement for intravenous administration of nutrition.\nsynonyms :\n'}


{'id': 'HP_0033995', 'url': 'http://purl.obolibrary.org/obo/HP_0033995', 'lbl': 'Microvillus inclusions', 'desc': 'label: Microvillus inclusions\ndefinition : The presence of vacuoles bearing centripetal microvilli in small gut villus enterocytes.\nsynonyms :\n'}


{'id': 'HP_0033996', 'url': 'http://purl.obolibrary.org/obo/HP_0033996', 'lbl': 'Microvillar PAS-positive secretory granules', 'desc': 'label: Microvillar PAS-positive secretory granules\ndefinition : The presenceaccumulationof periodic acid-Schiff (PAS) granules in the subapical region of small intenstinal microvilli, appearing as different kinds of vesicular/tubular structures.\nsynonyms :\n'}


{'id': 'HP_0033997', 'url': 'http://purl.obolibrary.org/obo/HP_0033997', 'lbl': 'Perinuclear cardiomyocyte vacuolization', 'desc': 'label: Perinuclear cardiomyocyte vacuolization\ndefinition : Formation of vacuoles, i.e., membrane-bound organelles, in the portion of the cytoplasm near the nucleus within myocytes of the heart.\nsynonyms :\n'}


{'id': 'HP_0033998', 'url': 'http://purl.obolibrary.org/obo/HP_0033998', 'lbl': 'Single-lobed right lung', 'desc': 'label: Single-lobed right lung\ndefinition : A developmental defect of pulmonary lobation characterized by the presence of only one lobe of the right lung, which normally has three lobes.\nsynonyms :\n'}


{'id': 'HP_0033999', 'url': 'http://purl.obolibrary.org/obo/HP_0033999', 'lbl': 'Bronchial hemorrhage', 'desc': 'label: Bronchial hemorrhage\ndefinition : Bronchial hemorrhage is a focal bleeding located in the bronchial system. It can be diagnosed by tracheobronchoscopy.\nsynonyms :Bronchial bleeding\n'}


{'id': 'HP_0034000', 'url': 'http://purl.obolibrary.org/obo/HP_0034000', 'lbl': 'Tracheal hemorrhage', 'desc': 'label: Tracheal hemorrhage\ndefinition : Tracheal hemorrhage is a focal bleeding within the trachea. It be diagnosed by tracheobronchoscopy.\nsynonyms :Tracheal bleeding\n'}


{'id': 'HP_0034001', 'url': 'http://purl.obolibrary.org/obo/HP_0034001', 'lbl': 'Anti-Complement factor H antibody positivity', 'desc': 'label: Anti-Complement factor H antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against complement factor H.\nsynonyms :CFH autoantibodies\n'}


{'id': 'HP_0034002', 'url': 'http://purl.obolibrary.org/obo/HP_0034002', 'lbl': 'Anti-phospholipase A2 receptor antibody positivity', 'desc': 'label: Anti-phospholipase A2 receptor antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against the phospholipase A2 receptor.\nsynonyms :Anti-PLA2R antibody positivity\n'}


{'id': 'HP_0034003', 'url': 'http://purl.obolibrary.org/obo/HP_0034003', 'lbl': 'Broad medial eyebrow', 'desc': 'label: Broad medial eyebrow\ndefinition : Regional increase in the width (height) of the middle portion of the eyebrow.\nsynonyms :Medial broadening of eyebrows\n'}


{'id': 'HP_0034004', 'url': 'http://purl.obolibrary.org/obo/HP_0034004', 'lbl': 'Parosmia', 'desc': 'label: Parosmia\ndefinition : Misperception of existing odor, that is, distorted or altered olfactory perception in the presence of known stimuli.\nsynonyms :\n'}


{'id': 'HP_0034005', 'url': 'http://purl.obolibrary.org/obo/HP_0034005', 'lbl': 'Decreased dendritic spine number', 'desc': 'label: Decreased dendritic spine number\ndefinition : An abnormal reduction in the amount of spines on a given dendrite.\nsynonyms :\n'}


{'id': 'HP_0034006', 'url': 'http://purl.obolibrary.org/obo/HP_0034006', 'lbl': 'Decreased urinary lysyl-pyridinoline-hydroxylysyl-pyridinoline ratio', 'desc': 'label: Decreased urinary lysyl-pyridinoline-hydroxylysyl-pyridinoline ratio\ndefinition : A decreased amount of the urinary cross-links lysyl-pyridinoline (LP, or deoxypyridinoline DPD) as compared to hydroxylysyl-pyridinoline (HP, or pyridinoline PYD). Both are established biochemical markers of osteoclastic bone resorption and collagen degradation.\nsynonyms :\n'}


{'id': 'HP_0034007', 'url': 'http://purl.obolibrary.org/obo/HP_0034007', 'lbl': 'Posterior atrophy of corpus callosum', 'desc': 'label: Posterior atrophy of corpus callosum\ndefinition : The presence of atrophy (wasting) of the posterior portion of the corpus callosum.\nsynonyms :\n'}


{'id': 'HP_0034008', 'url': 'http://purl.obolibrary.org/obo/HP_0034008', 'lbl': 'Opto-chiasmatic atrophy', 'desc': 'label: Opto-chiasmatic atrophy\ndefinition : Wasting (atrophy) of the optic chiasm.\nsynonyms :\n'}


{'id': 'HP_0034009', 'url': 'http://purl.obolibrary.org/obo/HP_0034009', 'lbl': 'Pelvic lipomatosis', 'desc': 'label: Pelvic lipomatosis\ndefinition : Overgrowth of fat in the perivesical and perirectal area.\nsynonyms :\n'}


{'id': 'HP_0034010', 'url': 'http://purl.obolibrary.org/obo/HP_0034010', 'lbl': 'Increased megakaryocyte colony forming unit count', 'desc': 'label: Increased megakaryocyte colony forming unit count\ndefinition : Increased numbers of megakryocyte precursors (megakaryocyte colony forming units) in the bone marrow.\nsynonyms :\n'}


{'id': 'HP_0034011', 'url': 'http://purl.obolibrary.org/obo/HP_0034011', 'lbl': 'Reduced progressive sperm motility', 'desc': 'label: Reduced progressive sperm motility\ndefinition : A reduced proportion of sperm that move in a straight line or large circles; alternatively, an increaed proportion of sperm that move in tight circles or in some other non-linear fashion.\nsynonyms :Non-progressive sperm motility\n'}


{'id': 'HP_0034012', 'url': 'http://purl.obolibrary.org/obo/HP_0034012', 'lbl': 'Palmoplantar hypohidrosis', 'desc': 'label: Palmoplantar hypohidrosis\ndefinition : Decreased sweating on the palms and soles.\nsynonyms :\n'}


{'id': 'HP_0034013', 'url': 'http://purl.obolibrary.org/obo/HP_0034013', 'lbl': 'Curvilinear pericallosal lipoma', 'desc': 'label: Curvilinear pericallosal lipoma\ndefinition : A type of pericallosal lipoma that is thin and curves around the posterior end of the splenium of the corpus callosum.\nsynonyms :\n'}


{'id': 'HP_0034014', 'url': 'http://purl.obolibrary.org/obo/HP_0034014', 'lbl': 'Tubulonodular pericallosal lipoma', 'desc': 'label: Tubulonodular pericallosal lipoma\ndefinition : A type of pericallosal lipoma with a rounded or lobular appearance and a diameter that is usually above 2 cm. They are anteriorly situated and are associated with extensive callosal and often fronto-facial anomalies. A tubulonodular pericallosal lipoma can extend into the choroid plexus or lateral ventricles.\nsynonyms :\n'}


{'id': 'HP_0034015', 'url': 'http://purl.obolibrary.org/obo/HP_0034015', 'lbl': 'Cavitating pulmonary nodule', 'desc': 'label: Cavitating pulmonary nodule\ndefinition : Thick-walled abnormal gas-filled interstitial nodule within a lung.\nsynonyms :\n'}


{'id': 'HP_0034016', 'url': 'http://purl.obolibrary.org/obo/HP_0034016', 'lbl': 'Anti-HLA antibody positivity', 'desc': 'label: Anti-HLA antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a human leukocyte antigen (HLA).\nsynonyms :Anti-human leukocyte antigen antibody positivity\n'}


{'id': 'HP_0034017', 'url': 'http://purl.obolibrary.org/obo/HP_0034017', 'lbl': 'Anti-class I HLA antibody positivity', 'desc': 'label: Anti-class I HLA antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a class I human leukocyte antigen (HLA). Class I HLA corresponds to MHC class I (A, B, and C).\nsynonyms :\n'}


{'id': 'HP_0034018', 'url': 'http://purl.obolibrary.org/obo/HP_0034018', 'lbl': 'Anti-class II HLA antibody positivity', 'desc': 'label: Anti-class II HLA antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a class I human leukocyte antigen (HLA). Class I HLA corresponds to MHC class II (DP, DM, DO, DQ, and DR).\nsynonyms :\n'}


{'id': 'HP_0034019', 'url': 'http://purl.obolibrary.org/obo/HP_0034019', 'lbl': 'Anti-HLA-A antibody positivity', 'desc': 'label: Anti-HLA-A antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a human leukocyte antigen-A (HLA-A).\nsynonyms :\n'}


{'id': 'HP_0034020', 'url': 'http://purl.obolibrary.org/obo/HP_0034020', 'lbl': 'Anti-HLA-A IgG1 antibody positivity', 'desc': 'label: Anti-HLA-A IgG1 antibody positivity\ndefinition : The presence of IgG1 autoantibodies in the blood circulation that react against a human leukocyte antigen-A (HLA-A).\nsynonyms :\n'}


{'id': 'HP_0034021', 'url': 'http://purl.obolibrary.org/obo/HP_0034021', 'lbl': 'Anti-HLA-A IgG3 antibody positivity', 'desc': 'label: Anti-HLA-A IgG3 antibody positivity\ndefinition : The presence of IgG3 autoantibodies in the blood circulation that react against a human leukocyte antigen-A (HLA-A).\nsynonyms :\n'}


{'id': 'HP_0034022', 'url': 'http://purl.obolibrary.org/obo/HP_0034022', 'lbl': 'Anti-HLA-B antibody positivity', 'desc': 'label: Anti-HLA-B antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a human leukocyte antigen-B (HLA-B).\nsynonyms :\n'}


{'id': 'HP_0034023', 'url': 'http://purl.obolibrary.org/obo/HP_0034023', 'lbl': 'Anti-HLA-B IgG1 antibody positivity', 'desc': 'label: Anti-HLA-B IgG1 antibody positivity\ndefinition : The presence of IgG1 autoantibodies in the blood circulation that react against a human leukocyte antigen-B (HLA-B).\nsynonyms :\n'}


{'id': 'HP_0034024', 'url': 'http://purl.obolibrary.org/obo/HP_0034024', 'lbl': 'Anti-HLA-B IgG3 antibody positivity', 'desc': 'label: Anti-HLA-B IgG3 antibody positivity\ndefinition : The presence of IgG3 autoantibodies in the blood circulation that react against a human leukocyte antigen-B (HLA-B).\nsynonyms :\n'}


{'id': 'HP_0034025', 'url': 'http://purl.obolibrary.org/obo/HP_0034025', 'lbl': 'Abnormal circulating GABA concentration', 'desc': 'label: Abnormal circulating GABA concentration\ndefinition : Any deviation from the normal concentration of gamma-aminobutyric acid (GABA) in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034026', 'url': 'http://purl.obolibrary.org/obo/HP_0034026', 'lbl': 'Elevated circulating sacchoropine concentration', 'desc': 'label: Elevated circulating sacchoropine concentration\ndefinition : An increased concentration of saccharopine in the blood circulation. L-saccharopine is the N(6)-(1,3-dicarboxypropan-1-yl) derivative of L-lysine.\nsynonyms :\n'}


{'id': 'HP_0034027', 'url': 'http://purl.obolibrary.org/obo/HP_0034027', 'lbl': 'Abnormal urinary non-proteinogenic amino acid level', 'desc': 'label: Abnormal urinary non-proteinogenic amino acid level\ndefinition : Any deviation from the normal amount in the urine of an alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.\nsynonyms :\n'}


{'id': 'HP_0034028', 'url': 'http://purl.obolibrary.org/obo/HP_0034028', 'lbl': 'Saccharopinuria', 'desc': 'label: Saccharopinuria\ndefinition : Presence of saccharopine in the urine.\nsynonyms :\n'}


{'id': 'HP_0034029', 'url': 'http://purl.obolibrary.org/obo/HP_0034029', 'lbl': 'Hepatic foam cells', 'desc': 'label: Hepatic foam cells\ndefinition : The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, in the liver.\nsynonyms :\n'}


{'id': 'HP_0034030', 'url': 'http://purl.obolibrary.org/obo/HP_0034030', 'lbl': 'Lip cyanosis', 'desc': 'label: Lip cyanosis\ndefinition : Bluish discoloration of the lips.\nsynonyms :Bluish lips; Cyanotic lips; Labial cyanosis\n'}


{'id': 'HP_0034031', 'url': 'http://purl.obolibrary.org/obo/HP_0034031', 'lbl': 'Facial cyanosis', 'desc': 'label: Facial cyanosis\ndefinition : Bluish discoloration of one or more regions of the face.\nsynonyms :Bluish face; Cyanotic face\n'}


{'id': 'HP_0034032', 'url': 'http://purl.obolibrary.org/obo/HP_0034032', 'lbl': 'Central cyanosis', 'desc': 'label: Central cyanosis\ndefinition : Generalized bluish discoloration of the body and the visible mucous membranes, which occurs due to inadequate oxygenation secondary to conditions that lead to an increase in deoxygenated hemoglobin or presence of abnormal hemoglobin.\nsynonyms :\n'}


{'id': 'HP_0034033', 'url': 'http://purl.obolibrary.org/obo/HP_0034033', 'lbl': 'Peripheral cyanosis', 'desc': 'label: Peripheral cyanosis\ndefinition : Bluish discoloration of the distal extremities (hands, fingertips, toes), and can sometimes involve circumoral and periorbital areas. Mucous membranes are generally not involved.\nsynonyms :\n'}


{'id': 'HP_0034034', 'url': 'http://purl.obolibrary.org/obo/HP_0034034', 'lbl': 'Differential cyanosis', 'desc': 'label: Differential cyanosis\ndefinition : Differential degree of bluish discoloration between the upper and lower extremities.\nsynonyms :\n'}


{'id': 'HP_0034035', 'url': 'http://purl.obolibrary.org/obo/HP_0034035', 'lbl': 'Pharyngeal exudate', 'desc': 'label: Pharyngeal exudate\ndefinition : Fluid exuded from the posterior wall of the pharynx.\nsynonyms :Fluid from the pharynx; Pharyngeal fluid\n'}


{'id': 'HP_0034036', 'url': 'http://purl.obolibrary.org/obo/HP_0034036', 'lbl': 'Pseudo-chilblains on toes', 'desc': 'label: Pseudo-chilblains on toes\ndefinition : Inflammatory chilblain-like nodules on the feet and/or toes.\nsynonyms :COVID toe; Chilblain-like toe lesions; Chilblain-like toes\n'}


{'id': 'HP_0034037', 'url': 'http://purl.obolibrary.org/obo/HP_0034037', 'lbl': 'Pseudo-chilblains on fingers', 'desc': 'label: Pseudo-chilblains on fingers\ndefinition : Inflammatory chilblain-like nodules on the hands and/or fingers.\nsynonyms :COVID finger; COVID fingers\n'}


{'id': 'HP_0034038', 'url': 'http://purl.obolibrary.org/obo/HP_0034038', 'lbl': 'Silent hypoxemia', 'desc': 'label: Silent hypoxemia\ndefinition : Abnormally low blood oxygen level without the presence of dyspnea.\nsynonyms :\n'}


{'id': 'HP_0034039', 'url': 'http://purl.obolibrary.org/obo/HP_0034039', 'lbl': 'Ventricular couplet', 'desc': 'label: Ventricular couplet\ndefinition : Two consecutive premature ventricular contractions (PVCs) with no intervening normal beats.\nsynonyms :Doublet premature ventricular contractions\n'}


{'id': 'HP_0034040', 'url': 'http://purl.obolibrary.org/obo/HP_0034040', 'lbl': 'Bidirectional ventricular tachycardia', 'desc': 'label: Bidirectional ventricular tachycardia\ndefinition : Bidirectional ventricular tachycardia (BDVT) is a regular ventricular tachyarrhythmia (VT) with two different QRS morphologies alternating at a rate typically between 140 and 180 bpm.\nsynonyms :\n'}


{'id': 'HP_0034041', 'url': 'http://purl.obolibrary.org/obo/HP_0034041', 'lbl': 'Ventricular ectopy', 'desc': 'label: Ventricular ectopy\ndefinition : Ventricular ectopics, also known as ventricular extrasystoles, premature ventricular contractions or complexes (PVC) and ventricular premature depolarisations (VPD) are beats arising from within the ventricles. When they occur in groupings such as bigeminy, trigeminy, couplets and triplets they are referred to as ventricular ectopy.\nsynonyms :\n'}


{'id': 'HP_0034042', 'url': 'http://purl.obolibrary.org/obo/HP_0034042', 'lbl': 'Dorsal hirsutism', 'desc': 'label: Dorsal hirsutism\ndefinition : Abnormally increased hair growth in the lskin of the back.\nsynonyms :\n'}


{'id': 'HP_0034043', 'url': 'http://purl.obolibrary.org/obo/HP_0034043', 'lbl': 'Increased fecal bile acid', 'desc': 'label: Increased fecal bile acid\ndefinition : Elevated amount of bile acids in the feces.\nsynonyms :\n'}


{'id': 'HP_0034044', 'url': 'http://purl.obolibrary.org/obo/HP_0034044', 'lbl': 'Trident pelvis', 'desc': 'label: Trident pelvis\ndefinition : Spurs at the medial and lateral acetabular margin and in the center of the acetabulum gives rise to shape resembling a three-pronged spear known as trident.\nsynonyms :Trident sign\n'}


{'id': 'HP_0034045', 'url': 'http://purl.obolibrary.org/obo/HP_0034045', 'lbl': 'Angulated muscle fibers', 'desc': 'label: Angulated muscle fibers\ndefinition : Normal muscle fibers are polygonal-shaped in cross section, are multinucleated, and have minimal amounts of endomysial connective tissue. In contrast, angulated (also known as angular) muscle fibers have long and narrow vertices (corners) with sharp edges and a pointed tip.\nsynonyms :Angular muscle fibers\n'}


{'id': 'HP_0034046', 'url': 'http://purl.obolibrary.org/obo/HP_0034046', 'lbl': 'Mandibular osteolysis', 'desc': 'label: Mandibular osteolysis\ndefinition : Osteolysis (destruction of bone through bone resorption with removal or loss of calcium) localized to the mandible.\nsynonyms :\n'}


{'id': 'HP_0034047', 'url': 'http://purl.obolibrary.org/obo/HP_0034047', 'lbl': 'Rib osteolysis', 'desc': 'label: Rib osteolysis\ndefinition : Osteolysis (destruction of bone through bone resorption with removal or loss of calcium) localized to a rib.\nsynonyms :\n'}


{'id': 'HP_0034048', 'url': 'http://purl.obolibrary.org/obo/HP_0034048', 'lbl': 'Decreased circulating chenodeoxycholic acid concentration', 'desc': 'label: Decreased circulating chenodeoxycholic acid concentration\ndefinition : A reduced concentration of chenodeoxycholic acid in the blood circulation.\nsynonyms :Decreased circulating chenodiol concentration\n'}


{'id': 'HP_0034049', 'url': 'http://purl.obolibrary.org/obo/HP_0034049', 'lbl': 'Elevated urinary prostaglandin E2 level', 'desc': 'label: Elevated urinary prostaglandin E2 level\ndefinition : An increased amount of prostaglandin E2 in the urine.\nsynonyms :Elevated urinary PGE2 level\n'}


{'id': 'HP_0034050', 'url': 'http://purl.obolibrary.org/obo/HP_0034050', 'lbl': 'Elevated urinary prostaglandin E2 metabolite level', 'desc': 'label: Elevated urinary prostaglandin E2 metabolite level\ndefinition : An increased amount of prostaglandin E2 metabolite (PGE-M) in the urine.\nsynonyms :\n'}


{'id': 'HP_0034051', 'url': 'http://purl.obolibrary.org/obo/HP_0034051', 'lbl': 'Hypoplastic anterior limbs of the internal capsule', 'desc': 'label: Hypoplastic anterior limbs of the internal capsule\ndefinition : Underdevelopment of the frontal part (anterior crus or anterior limb) of the internal capsule.\nsynonyms :\n'}


{'id': 'HP_0034052', 'url': 'http://purl.obolibrary.org/obo/HP_0034052', 'lbl': 'Impaired toe-walking ability', 'desc': 'label: Impaired toe-walking ability\ndefinition : Difficulty or reduced ability to walk on toes. Toe-walking can be tested as a part of the neurological examination. Foot plantar flexion weakness leads to difficulties in walking on toes.\nsynonyms :\n'}


{'id': 'HP_0034053', 'url': 'http://purl.obolibrary.org/obo/HP_0034053', 'lbl': 'Decreased acid ceramidase activity', 'desc': 'label: Decreased acid ceramidase activity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0034054', 'url': 'http://purl.obolibrary.org/obo/HP_0034054', 'lbl': 'Probst bundles', 'desc': 'label: Probst bundles\ndefinition : Probst bundles (also known as longitudinal callosal fascicles) are neuroanatomical homologues to the corpus callosum and can occur in association with callosal agenesis. Probst bundles are white matter fibers that normally cross the corpus callosum but (because of the agenesis of the corpus callosum) fail to cross the midline, such that when they reach the corticoseptal boundary, they turn and run parallel to the interhemispheric fissure within the septal leaves, indenting the medial walls of the lateral ventricles.\nsynonyms :\n'}


{'id': 'HP_0034055', 'url': 'http://purl.obolibrary.org/obo/HP_0034055', 'lbl': 'Anti-side-chain cleavage enzyme antibody positivity', 'desc': 'label: Anti-side-chain cleavage enzyme antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc), which is encoded by CYP11A1 cytochrome P450 family 11 subfamily A member 1 (Gene ID:1583).\nsynonyms :Anti-P450scc\n'}


{'id': 'HP_0034056', 'url': 'http://purl.obolibrary.org/obo/HP_0034056', 'lbl': 'Increased fecal calprotectin level', 'desc': 'label: Increased fecal calprotectin level\ndefinition : An increased amount of calprotectin in the feces.\nsynonyms :\n'}


{'id': 'HP_0034057', 'url': 'http://purl.obolibrary.org/obo/HP_0034057', 'lbl': 'Fetal anomaly', 'desc': 'label: Fetal anomaly\ndefinition : Structural or functional abnormalities of the fetus. Note that this section comprises terms that describe abnormalities that are specific to the fetus or differ from the corresponding general terms. A term from anywhere in the Human Phenotype Ontology can be applied to a fetus if appropriate.\nsynonyms :\n'}


{'id': 'HP_0034058', 'url': 'http://purl.obolibrary.org/obo/HP_0034058', 'lbl': 'Abnormal fetal morphology', 'desc': 'label: Abnormal fetal morphology\ndefinition : Any structural anomaly of the fetus.\nsynonyms :Structural fetal anomaly\n'}


{'id': 'HP_0034059', 'url': 'http://purl.obolibrary.org/obo/HP_0034059', 'lbl': 'Abnormal fetal physiology', 'desc': 'label: Abnormal fetal physiology\ndefinition : Any functional anomaly of the fetus.\nsynonyms :Functional fetal anomaly\n'}


{'id': 'HP_0034060', 'url': 'http://purl.obolibrary.org/obo/HP_0034060', 'lbl': 'Triggered by fava bean ingestion', 'desc': 'label: Triggered by fava bean ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating fava beans.\nsynonyms :\n'}


{'id': 'HP_0034061', 'url': 'http://purl.obolibrary.org/obo/HP_0034061', 'lbl': 'Anti-steroid 17alpha-hydroxylase antibody positivity', 'desc': 'label: Anti-steroid 17alpha-hydroxylase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against steroid 17alpha-hydroxylase.\nsynonyms :Anti-P450C17\n'}


{'id': 'HP_0034062', 'url': 'http://purl.obolibrary.org/obo/HP_0034062', 'lbl': 'Anti-insulin antibody positivity', 'desc': 'label: Anti-insulin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against insulin.\nsynonyms :IAA positivity; Insulin autoantibodies\n'}


{'id': 'HP_0034063', 'url': 'http://purl.obolibrary.org/obo/HP_0034063', 'lbl': 'Anti-islet antigen-2 antibody positivity', 'desc': 'label: Anti-islet antigen-2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against tyrosine phosphatase IA-2.\nsynonyms :Anti-IA2 antibody positivity; Anti-IA2A; ICA512\n'}


{'id': 'HP_0034064', 'url': 'http://purl.obolibrary.org/obo/HP_0034064', 'lbl': 'Anti-salivary protein antibody positivity', 'desc': 'label: Anti-salivary protein antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against salivary protein.\nsynonyms :Anti-SP1 antibody positivity\n'}


{'id': 'HP_0034065', 'url': 'http://purl.obolibrary.org/obo/HP_0034065', 'lbl': 'Anti-Zinc transporter 8 antibody positivity', 'desc': 'label: Anti-Zinc transporter 8 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against zinc transporter 8.\nsynonyms :Anti ZnT8 autoantibodies\n'}


{'id': 'HP_0034066', 'url': 'http://purl.obolibrary.org/obo/HP_0034066', 'lbl': 'Anti-carbonic anhydrase VI antibody positivity', 'desc': 'label: Anti-carbonic anhydrase VI antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against carbonic anhydrase VI.\nsynonyms :Anti-CA6 antibody positivity\n'}


{'id': 'HP_0034067', 'url': 'http://purl.obolibrary.org/obo/HP_0034067', 'lbl': 'Tonofilament clumping', 'desc': 'label: Tonofilament clumping\ndefinition : Formation of lumps of tonofilaments, which are bundles of keratin filaments. In some but not all epithelia, keratin filaments are conspicuously bundled as tonofilaments. Inside the cell they braid the nucleus, span through the cytoplasm and are attached to the cytoplasmic plaques of the typical epithelial cell-cell junctions, the desmosomes.\nsynonyms :Clumping of the keratin tonofilaments\n'}


{'id': 'HP_0034068', 'url': 'http://purl.obolibrary.org/obo/HP_0034068', 'lbl': 'Anti-plasminogen binding peptide antibody positivity', 'desc': 'label: Anti-plasminogen binding peptide antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against plasminogen binding peptide.\nsynonyms :Anti-PBP antibody positivity\n'}


{'id': 'HP_0034069', 'url': 'http://purl.obolibrary.org/obo/HP_0034069', 'lbl': 'Anti-parotid secretory protein antibody positivity', 'desc': 'label: Anti-parotid secretory protein antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against parotid secretory protein.\nsynonyms :Anti-PSP antibody positivity\n'}


{'id': 'HP_0034070', 'url': 'http://purl.obolibrary.org/obo/HP_0034070', 'lbl': 'Anti-enterocyte antibody positivity', 'desc': 'label: Anti-enterocyte antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against enterocytes.\nsynonyms :AEA\n'}


{'id': 'HP_0034071', 'url': 'http://purl.obolibrary.org/obo/HP_0034071', 'lbl': 'Anti-21-hydroxylase antibody positivity', 'desc': 'label: Anti-21-hydroxylase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against 21-hydroxylase.\nsynonyms :Anti-P450c21\n'}


{'id': 'HP_0034072', 'url': 'http://purl.obolibrary.org/obo/HP_0034072', 'lbl': 'Abnormal fetal long-bone echogenicity', 'desc': 'label: Abnormal fetal long-bone echogenicity\ndefinition : Any deviation from the normal appearing echogenicity of the fetal bone. Echogenicity refers to the ability of tissue to reflect ultrasound waves back toward the transducer and produce an echo. Whenever there is an interface of structures with different echogenicities, a visible difference in contrast will be apparent on the screen. The higher the echogenicity of tissues, the brighter they appear on ultrasound imaging.\nsynonyms :\n'}


{'id': 'HP_0034073', 'url': 'http://purl.obolibrary.org/obo/HP_0034073', 'lbl': 'Reduced fetal long bone echogenicity', 'desc': 'label: Reduced fetal long bone echogenicity\ndefinition : An abnormally decreased echogenicity of fetal long bones in a prenatal sonographic investigation. Ths finding is due to hypomineralization and can be seen in some disorders such as hypophosphatasia, osteogenesis imperfecta, and achondrogenesis.\nsynonyms :\n'}


{'id': 'HP_0034074', 'url': 'http://purl.obolibrary.org/obo/HP_0034074', 'lbl': 'Increased fetal long bone echogenicity', 'desc': 'label: Increased fetal long bone echogenicity\ndefinition : An abnormally elevated echogenicity of fetal long bones in a prenatal sonographic investigation. This finding is due to hypermineralization.\nsynonyms :\n'}


{'id': 'HP_0034075', 'url': 'http://purl.obolibrary.org/obo/HP_0034075', 'lbl': 'Decreased circulating apolipoprotein B concentration', 'desc': 'label: Decreased circulating apolipoprotein B concentration\ndefinition : Reduced circulating level of apolipoprotein B, which is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100.\nsynonyms :\n'}


{'id': 'HP_0034076', 'url': 'http://purl.obolibrary.org/obo/HP_0034076', 'lbl': 'Anti-ribosome Po antibody positivity', 'desc': 'label: Anti-ribosome Po antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ribosome Po.\nsynonyms :\n'}


{'id': 'HP_0034077', 'url': 'http://purl.obolibrary.org/obo/HP_0034077', 'lbl': 'Anti-complement component C1q antibody positivity', 'desc': 'label: Anti-complement component C1q antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against C1q.\nsynonyms :Anti-C1q antibody positivity\n'}


{'id': 'HP_0034078', 'url': 'http://purl.obolibrary.org/obo/HP_0034078', 'lbl': 'Anti-centromere protein A antibody positivity', 'desc': 'label: Anti-centromere protein A antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against CENP-A.\nsynonyms :Anti-CENP-A antibody positivity\n'}


{'id': 'HP_0034079', 'url': 'http://purl.obolibrary.org/obo/HP_0034079', 'lbl': 'Anti-centromere protein B antibody positivity', 'desc': 'label: Anti-centromere protein B antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against CENP-B.\nsynonyms :Anti-CENP-B antibody positivity\n'}


{'id': 'HP_0034080', 'url': 'http://purl.obolibrary.org/obo/HP_0034080', 'lbl': 'Anti-U3 RNP antibody positivity', 'desc': 'label: Anti-U3 RNP antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against U3 RNP.\nsynonyms :Anti-fibrillarin antibody positivity\n'}


{'id': 'HP_0034081', 'url': 'http://purl.obolibrary.org/obo/HP_0034081', 'lbl': 'Anti-Th/To antibody positivity', 'desc': 'label: Anti-Th/To antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Th/To.\nsynonyms :\n'}


{'id': 'HP_0034082', 'url': 'http://purl.obolibrary.org/obo/HP_0034082', 'lbl': 'Anti-bicaudal D2 antibody positivity', 'desc': 'label: Anti-bicaudal D2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against bicaudal D2.\nsynonyms :Anti-BICD2 antibody positivity\n'}


{'id': 'HP_0034083', 'url': 'http://purl.obolibrary.org/obo/HP_0034083', 'lbl': 'Anti-nucleolus-organizing region antibody positivity', 'desc': 'label: Anti-nucleolus-organizing region antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Nor90.\nsynonyms :Anti-Nor90 antibody positivity\n'}


{'id': 'HP_0034084', 'url': 'http://purl.obolibrary.org/obo/HP_0034084', 'lbl': 'Anti-phosphatidyl ethanolamine antibody positivity', 'desc': 'label: Anti-phosphatidyl ethanolamine antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidyl ethanolamine.\nsynonyms :\n'}


{'id': 'HP_0034085', 'url': 'http://purl.obolibrary.org/obo/HP_0034085', 'lbl': 'Anti-PM-Scl100 antibody positivity', 'desc': 'label: Anti-PM-Scl100 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against PM-Scl100.\nsynonyms :\n'}


{'id': 'HP_0034086', 'url': 'http://purl.obolibrary.org/obo/HP_0034086', 'lbl': 'Anti-PM-Scl75 antibody positivity', 'desc': 'label: Anti-PM-Scl75 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against PM-Scl75.\nsynonyms :\n'}


{'id': 'HP_0034087', 'url': 'http://purl.obolibrary.org/obo/HP_0034087', 'lbl': 'Anti-U11/U12 RNP antibody positivity', 'desc': 'label: Anti-U11/U12 RNP antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against U11/U12 RNP.\nsynonyms :\n'}


{'id': 'HP_0034088', 'url': 'http://purl.obolibrary.org/obo/HP_0034088', 'lbl': 'Anti-Ku antibody positivity', 'desc': 'label: Anti-Ku antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ku.\nsynonyms :\n'}


{'id': 'HP_0034089', 'url': 'http://purl.obolibrary.org/obo/HP_0034089', 'lbl': 'Anti-B23 antibody positivity', 'desc': 'label: Anti-B23 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against B23.\nsynonyms :\n'}


{'id': 'HP_0034090', 'url': 'http://purl.obolibrary.org/obo/HP_0034090', 'lbl': 'Anti-RuvBL1/2 antibody positivity', 'desc': 'label: Anti-RuvBL1/2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against RuvBL1/2.\nsynonyms :\n'}


{'id': 'HP_0034091', 'url': 'http://purl.obolibrary.org/obo/HP_0034091', 'lbl': 'Anti-platelet derived growth factor receptor', 'desc': 'label: Anti-platelet derived growth factor receptor\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against platelet derived growth factor receptor.\nsynonyms :Anti-PDGFR antibody positivity\n'}


{'id': 'HP_0034092', 'url': 'http://purl.obolibrary.org/obo/HP_0034092', 'lbl': 'Anti-cyclic citrullinated peptide antibody positivity', 'desc': 'label: Anti-cyclic citrullinated peptide antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against cyclic citrullinated peptide.\nsynonyms :Anti-CCP antibody positivity\n'}


{'id': 'HP_0034093', 'url': 'http://purl.obolibrary.org/obo/HP_0034093', 'lbl': 'Anti-Ro52/TRIM21 antibody positivity', 'desc': 'label: Anti-Ro52/TRIM21 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ro52/TRIM21.\nsynonyms :Anti-Ro52 antibody positivity\n'}


{'id': 'HP_0034094', 'url': 'http://purl.obolibrary.org/obo/HP_0034094', 'lbl': 'Anti-angiotensin receptor type-1 antibody positivity', 'desc': 'label: Anti-angiotensin receptor type-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against angiotensin receptor type-1.\nsynonyms :Anti-AT1R antibody positivity\n'}


{'id': 'HP_0034095', 'url': 'http://purl.obolibrary.org/obo/HP_0034095', 'lbl': 'Anti-endothelin-1 type A receptor antibody positivity', 'desc': 'label: Anti-endothelin-1 type A receptor antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against endothelin-1 type A receptor.\nsynonyms :Anti-ETAR antibody positivity\n'}


{'id': 'HP_0034096', 'url': 'http://purl.obolibrary.org/obo/HP_0034096', 'lbl': 'Anti-phosphatidic acid antibody positivity', 'desc': 'label: Anti-phosphatidic acid antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidic acid.\nsynonyms :\n'}


{'id': 'HP_0034097', 'url': 'http://purl.obolibrary.org/obo/HP_0034097', 'lbl': 'Anti-phosphatidyl choline antibody positivity', 'desc': 'label: Anti-phosphatidyl choline antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidyl choline.\nsynonyms :\n'}


{'id': 'HP_0034098', 'url': 'http://purl.obolibrary.org/obo/HP_0034098', 'lbl': 'Anti-phosphatidyl glycerol antibody positivity', 'desc': 'label: Anti-phosphatidyl glycerol antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidyl glycerol.\nsynonyms :\n'}


{'id': 'HP_0034099', 'url': 'http://purl.obolibrary.org/obo/HP_0034099', 'lbl': 'Anti-phosphatidyl inositol antibody positivity', 'desc': 'label: Anti-phosphatidyl inositol antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidyl inositol.\nsynonyms :\n'}


{'id': 'HP_0034100', 'url': 'http://purl.obolibrary.org/obo/HP_0034100', 'lbl': 'Anti-phosphatidyl serine antibody positivity', 'desc': 'label: Anti-phosphatidyl serine antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phosphatidyl serine.\nsynonyms :\n'}


{'id': 'HP_0034101', 'url': 'http://purl.obolibrary.org/obo/HP_0034101', 'lbl': 'Anti-annexin-V antibody positivity', 'desc': 'label: Anti-annexin-V antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against annexin-V.\nsynonyms :\n'}


{'id': 'HP_0034102', 'url': 'http://purl.obolibrary.org/obo/HP_0034102', 'lbl': 'Anti-sphingolipid antibody positivity', 'desc': 'label: Anti-sphingolipid antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against sphingolipids.\nsynonyms :\n'}


{'id': 'HP_0034103', 'url': 'http://purl.obolibrary.org/obo/HP_0034103', 'lbl': 'Anti-GM1 antibody positivity', 'desc': 'label: Anti-GM1 antibody positivity\ndefinition : Ganglioside-monosialic acid (GM1) is a type of glycosphingolipid with one sialic acid. GM1 is located on the outer layer of the plasma membrane, and plays a vital role in neurogenesis, nerve development, differentiation and repair after injury\nsynonyms :Anti-ganglioside-monosialic acid antibody positivity\n'}


{'id': 'HP_0034104', 'url': 'http://purl.obolibrary.org/obo/HP_0034104', 'lbl': 'Anti-neutrophil elastase antibody positivity', 'desc': 'label: Anti-neutrophil elastase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against neutrophil elastase.\nsynonyms :\n'}


{'id': 'HP_0034105', 'url': 'http://purl.obolibrary.org/obo/HP_0034105', 'lbl': 'Anti-transcription intermediary factor-1gamma antibody positivity', 'desc': 'label: Anti-transcription intermediary factor-1gamma antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against transcription intermediary factor-1gamma.\nsynonyms :Anti-TIF-1gamma antibody positivity; Anti-TIF1-gamma antibody positivity\n'}


{'id': 'HP_0034106', 'url': 'http://purl.obolibrary.org/obo/HP_0034106', 'lbl': 'Anti-Su antigen/argonaute 2 antibody positivity', 'desc': 'label: Anti-Su antigen/argonaute 2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Su antigen/argonaute 2.\nsynonyms :Anti-Ago2 antibody positivity; Anti-Su antibody positivity\n'}


{'id': 'HP_0034107', 'url': 'http://purl.obolibrary.org/obo/HP_0034107', 'lbl': 'Anti-p53 antibody positivity', 'desc': 'label: Anti-p53 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against p53.\nsynonyms :\n'}


{'id': 'HP_0034108', 'url': 'http://purl.obolibrary.org/obo/HP_0034108', 'lbl': 'Anti-Y-box protein-1 antibody positivity', 'desc': 'label: Anti-Y-box protein-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Y-box protein-1.\nsynonyms :Anti-YB 1 antibody positivity\n'}


{'id': 'HP_0034109', 'url': 'http://purl.obolibrary.org/obo/HP_0034109', 'lbl': 'Anti-GW182 antibody positivity', 'desc': 'label: Anti-GW182 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against GW182.\nsynonyms :\n'}


{'id': 'HP_0034110', 'url': 'http://purl.obolibrary.org/obo/HP_0034110', 'lbl': 'Anti-Gerbich phenotype 1 antibody positivity', 'desc': 'label: Anti-Gerbich phenotype 1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ge-1.\nsynonyms :Anti-Ge-1 antibody positivity\n'}


{'id': 'HP_0034111', 'url': 'http://purl.obolibrary.org/obo/HP_0034111', 'lbl': 'Anti-MIT3 antibody positivity', 'desc': 'label: Anti-MIT3 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against MIT3.\nsynonyms :\n'}


{'id': 'HP_0034112', 'url': 'http://purl.obolibrary.org/obo/HP_0034112', 'lbl': 'Anti-GM1 IgG antibody positivity', 'desc': 'label: Anti-GM1 IgG antibody positivity\ndefinition : The presence of IgG autoantibodies (immunoglobulins) in the blood circulation that react against GM1.\nsynonyms :\n'}


{'id': 'HP_0034113', 'url': 'http://purl.obolibrary.org/obo/HP_0034113', 'lbl': 'obsolete Anti-type I liver-kidney microsomal antibody positivity', 'desc': 'label: obsolete Anti-type I liver-kidney microsomal antibody positivity\ndefinition : The presence of type I liver-kidney microsomal autoantibodies (immunoglobulins) in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034114', 'url': 'http://purl.obolibrary.org/obo/HP_0034114', 'lbl': 'Anti-hexokinase-1 antibody positivity', 'desc': 'label: Anti-hexokinase-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against hexokinase-1.\nsynonyms :Anti-HK-1 antibody positivity\n'}


{'id': 'HP_0034115', 'url': 'http://purl.obolibrary.org/obo/HP_0034115', 'lbl': 'Anti-Kelch like protein 12 antibody positivity', 'desc': 'label: Anti-Kelch like protein 12 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Kelch like protein 12.\nsynonyms :Anti-KLHL-12 antibody positivity\n'}


{'id': 'HP_0034116', 'url': 'http://purl.obolibrary.org/obo/HP_0034116', 'lbl': 'Anti-thyrotropin receptor antibody', 'desc': 'label: Anti-thyrotropin receptor antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against thyrotropin receptor antibody.\nsynonyms :\n'}


{'id': 'HP_0034117', 'url': 'http://purl.obolibrary.org/obo/HP_0034117', 'lbl': 'Anti-angiotensin-converting enzyme 2 antibody positivity', 'desc': 'label: Anti-angiotensin-converting enzyme 2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against angiotensin-converting enzyme 2.\nsynonyms :Anti-ACE2 antibody positivity\n'}


{'id': 'HP_0034118', 'url': 'http://purl.obolibrary.org/obo/HP_0034118', 'lbl': 'Anti-GM1 IgM antibody positivity', 'desc': 'label: Anti-GM1 IgM antibody positivity\ndefinition : The presence of IgM autoantibodies (immunoglobulins) in the blood circulation that react against GM1.\nsynonyms :\n'}


{'id': 'HP_0034119', 'url': 'http://purl.obolibrary.org/obo/HP_0034119', 'lbl': 'Anti-GD1a IgG antibody positivity', 'desc': 'label: Anti-GD1a IgG antibody positivity\ndefinition : The presence of IgG autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside D1a.\nsynonyms :\n'}


{'id': 'HP_0034120', 'url': 'http://purl.obolibrary.org/obo/HP_0034120', 'lbl': 'Anti-GD1a IgM antibody positivity', 'desc': 'label: Anti-GD1a IgM antibody positivity\ndefinition : The presence of IgM autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside D1a.\nsynonyms :\n'}


{'id': 'HP_0034121', 'url': 'http://purl.obolibrary.org/obo/HP_0034121', 'lbl': 'Anti-GD1a antibody positivity', 'desc': 'label: Anti-GD1a antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside D1a.\nsynonyms :\n'}


{'id': 'HP_0034122', 'url': 'http://purl.obolibrary.org/obo/HP_0034122', 'lbl': 'Anti-GQ1b antibody positivity', 'desc': 'label: Anti-GQ1b antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside Q1b.\nsynonyms :\n'}


{'id': 'HP_0034123', 'url': 'http://purl.obolibrary.org/obo/HP_0034123', 'lbl': 'Anti-GQ1b IgM antibody positivity', 'desc': 'label: Anti-GQ1b IgM antibody positivity\ndefinition : The presence of IgM autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside Q1b.\nsynonyms :\n'}


{'id': 'HP_0034124', 'url': 'http://purl.obolibrary.org/obo/HP_0034124', 'lbl': 'Anti-GD1b antibody positivity', 'desc': 'label: Anti-GD1b antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against GD1b ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034125', 'url': 'http://purl.obolibrary.org/obo/HP_0034125', 'lbl': 'Anti-GD1b IgM antibody positivity', 'desc': 'label: Anti-GD1b IgM antibody positivity\ndefinition : The presence of IgM autoantibodies (immunoglobulins) in the blood circulation that react against GD1b ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034126', 'url': 'http://purl.obolibrary.org/obo/HP_0034126', 'lbl': 'Anti-GD1b IgG antibody positivity', 'desc': 'label: Anti-GD1b IgG antibody positivity\ndefinition : The presence of IgG autoantibodies (immunoglobulins) in the blood circulation that react against GD1b ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034127', 'url': 'http://purl.obolibrary.org/obo/HP_0034127', 'lbl': 'Anti-GQ1b IgG antibody positivity', 'desc': 'label: Anti-GQ1b IgG antibody positivity\ndefinition : The presence of IgG autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside Q1b.\nsynonyms :\n'}


{'id': 'HP_0034128', 'url': 'http://purl.obolibrary.org/obo/HP_0034128', 'lbl': 'Anti-GT1a antibody positivity', 'desc': 'label: Anti-GT1a antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against T1a ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034129', 'url': 'http://purl.obolibrary.org/obo/HP_0034129', 'lbl': 'Anti-GT1a IgM antibody positivity', 'desc': 'label: Anti-GT1a IgM antibody positivity\ndefinition : The presence of IgM autoantibodies (immunoglobulins) in the blood circulation that react against T1a ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034130', 'url': 'http://purl.obolibrary.org/obo/HP_0034130', 'lbl': 'Anti-GT1a IgG antibody positivity', 'desc': 'label: Anti-GT1a IgG antibody positivity\ndefinition : The presence of IgG autoantibodies (immunoglobulins) in the blood circulation that react against T1a ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034131', 'url': 'http://purl.obolibrary.org/obo/HP_0034131', 'lbl': 'Anti-GT1b antibody positivity', 'desc': 'label: Anti-GT1b antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against T1b ganglioside.\nsynonyms :\n'}


{'id': 'HP_0034132', 'url': 'http://purl.obolibrary.org/obo/HP_0034132', 'lbl': 'Anti-GM2 antibody positivity', 'desc': 'label: Anti-GM2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside GM2.\nsynonyms :\n'}


{'id': 'HP_0034133', 'url': 'http://purl.obolibrary.org/obo/HP_0034133', 'lbl': 'Anti-GM3 antibody positivity', 'desc': 'label: Anti-GM3 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside GM3.\nsynonyms :\n'}


{'id': 'HP_0034134', 'url': 'http://purl.obolibrary.org/obo/HP_0034134', 'lbl': 'Anti-GM4 antibody positivity', 'desc': 'label: Anti-GM4 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ganglioside GM4.\nsynonyms :\n'}


{'id': 'HP_0034135', 'url': 'http://purl.obolibrary.org/obo/HP_0034135', 'lbl': 'Anti-neurofascin-155 antibody positivity', 'desc': 'label: Anti-neurofascin-155 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against NF155.\nsynonyms :Anti-NF155 antibody positivity\n'}


{'id': 'HP_0034136', 'url': 'http://purl.obolibrary.org/obo/HP_0034136', 'lbl': 'Anti-neurofascin 186 antibody positivity', 'desc': 'label: Anti-neurofascin 186 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against NF186.\nsynonyms :Anti-NF186 antibody positivity\n'}


{'id': 'HP_0034137', 'url': 'http://purl.obolibrary.org/obo/HP_0034137', 'lbl': 'Anti-contactin-1 antibody positivity', 'desc': 'label: Anti-contactin-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against CNTN1.\nsynonyms :Anti-CNTN1 antibody positivity\n'}


{'id': 'HP_0034138', 'url': 'http://purl.obolibrary.org/obo/HP_0034138', 'lbl': 'Anti-contactin-associated protein 1 antibody positivity', 'desc': 'label: Anti-contactin-associated protein 1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against anti-contactin-associated protein 1.\nsynonyms :Anti-CASPR1 antibody positivity\n'}


{'id': 'HP_0034139', 'url': 'http://purl.obolibrary.org/obo/HP_0034139', 'lbl': 'Anti-SUMO-activating enzyme antibody positivity', 'desc': 'label: Anti-SUMO-activating enzyme antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against SAE.\nsynonyms :Anti-SAE antibody positivity; Anti-small ubiquitin-like modifier-1 activating enzyme antibody positivity\n'}


{'id': 'HP_0034140', 'url': 'http://purl.obolibrary.org/obo/HP_0034140', 'lbl': 'Anti-SUMO-activating enzyme subunit 1 antibody positivity', 'desc': 'label: Anti-SUMO-activating enzyme subunit 1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against SAE 1.\nsynonyms :\n'}


{'id': 'HP_0034141', 'url': 'http://purl.obolibrary.org/obo/HP_0034141', 'lbl': 'Anti-SUMO-activating enzyme subunit 2 antibody positivity', 'desc': 'label: Anti-SUMO-activating enzyme subunit 2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against SAE 2.\nsynonyms :Anti-SAE 2 antibody positivity\n'}


{'id': 'HP_0034142', 'url': 'http://purl.obolibrary.org/obo/HP_0034142', 'lbl': 'Anti-nuclear matrix protein-2 antibody positivity', 'desc': 'label: Anti-nuclear matrix protein-2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against NXP-2.\nsynonyms :Anti-MJ/NXP-2 antibody positivity; Anti-NXP-2 antibody positivity\n'}


{'id': 'HP_0034143', 'url': 'http://purl.obolibrary.org/obo/HP_0034143', 'lbl': 'Anti-threonyl-tRNA synthetase antibody positivity', 'desc': 'label: Anti-threonyl-tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against threonyl-tRNA synthetase.\nsynonyms :Anti-PL-7 antibody positivity\n'}


{'id': 'HP_0034144', 'url': 'http://purl.obolibrary.org/obo/HP_0034144', 'lbl': 'Anti-hY-RNA complex antibody positivity', 'desc': 'label: Anti-hY-RNA complex antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ro60.\nsynonyms :Anti-Ro60 antibody positivity\n'}


{'id': 'HP_0034145', 'url': 'http://purl.obolibrary.org/obo/HP_0034145', 'lbl': 'Anti-alanyl-tRNA synthetase antibody positivity', 'desc': 'label: Anti-alanyl-tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against alanyl-tRNA synthetase.\nsynonyms :Anti-PL-12 antibody positivity\n'}


{'id': 'HP_0034146', 'url': 'http://purl.obolibrary.org/obo/HP_0034146', 'lbl': 'Anti-glycyl tRNA-synthetase antibody positivity', 'desc': 'label: Anti-glycyl tRNA-synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against glycyl tRNA-synthetase.\nsynonyms :Anti-EJ antibody positivity\n'}


{'id': 'HP_0034147', 'url': 'http://purl.obolibrary.org/obo/HP_0034147', 'lbl': 'Anti-aminoacyl-tRNA synthetase antibody positivity', 'desc': 'label: Anti-aminoacyl-tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against a tRNA synthetase enzyme.\nsynonyms :\n'}


{'id': 'HP_0034148', 'url': 'http://purl.obolibrary.org/obo/HP_0034148', 'lbl': 'Anti-isoleucyl tRNA-synthetase antibody positivity', 'desc': 'label: Anti-isoleucyl tRNA-synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against isoleucyl tRNA-synthetase.\nsynonyms :Anti-OJ antibody positivity\n'}


{'id': 'HP_0034149', 'url': 'http://purl.obolibrary.org/obo/HP_0034149', 'lbl': 'Anti-phenylalanyl tRNA synthetase antibody positivity', 'desc': 'label: Anti-phenylalanyl tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against phenylalanyl tRNA synthetase.\nsynonyms :Anti-Zo alpha antibody positivity; Anti-Zo antibody positivity; Phenylanyl-t-RNA synthetase alpha antibody positivity\n'}


{'id': 'HP_0034150', 'url': 'http://purl.obolibrary.org/obo/HP_0034150', 'lbl': 'Anti-tyrosyl-tRNA synthetase antibody positivity', 'desc': 'label: Anti-tyrosyl-tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against tyrosyl-tRNA synthetase.\nsynonyms :Anti-Ha antibody positivity\n'}


{'id': 'HP_0034151', 'url': 'http://purl.obolibrary.org/obo/HP_0034151', 'lbl': 'Anti-asparaginyl-tRNA synthetase antibody positivity', 'desc': 'label: Anti-asparaginyl-tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against asparaginyl-tRNA synthetase.\nsynonyms :Anti-KS antibody positivity\n'}


{'id': 'HP_0034152', 'url': 'http://purl.obolibrary.org/obo/HP_0034152', 'lbl': 'Anti-histidyl tRNA synthetase antibody positivity', 'desc': 'label: Anti-histidyl tRNA synthetase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against histidyl tRNA synthetase.\nsynonyms :Anti-JO1 antibody positivity; Anti-Jo-1 antibody positivity\n'}


{'id': 'HP_0034153', 'url': 'http://purl.obolibrary.org/obo/HP_0034153', 'lbl': 'Anti-cytosolic-5-nucleotidase-1A antibody positivity', 'desc': 'label: Anti-cytosolic-5-nucleotidase-1A antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against cytosolic-5-nucleotidase-1A (cN1A).\nsynonyms :Anti-cN1A antibody positivity\n'}


{'id': 'HP_0034154', 'url': 'http://purl.obolibrary.org/obo/HP_0034154', 'lbl': 'Anti-Ki antibody positivity', 'desc': 'label: Anti-Ki antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ki.\nsynonyms :\n'}


{'id': 'HP_0034155', 'url': 'http://purl.obolibrary.org/obo/HP_0034155', 'lbl': 'Anti-sp100 antibody positivity', 'desc': 'label: Anti-sp100 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against sp100. Autoantibodies causing the MND pattern are directed against sp100, sp140, promyelocytic leukemia nuclear body proteins (PML) or ubiquitin-like modifier (SUMO) proteins, while in the punctate nuclear envelope pattern, the target antigens are gp210, nucleoporin-62 or laminin B receptor proteins.\nsynonyms :\n'}


{'id': 'HP_0034156', 'url': 'http://purl.obolibrary.org/obo/HP_0034156', 'lbl': 'Anti-beta-2-Glycoprotein I IgG antibody positivity', 'desc': 'label: Anti-beta-2-Glycoprotein I IgG antibody positivity\ndefinition : Presence of IgG antibodies against beta 2 glycoprotein I in the circulation. Beta-2 glycoprotein I (beta2GPI) is the principal target of autoantibodies in the antiphospholipid syndrome.\nsynonyms :Anti-beta2GPI IgG antibody positivity\n'}


{'id': 'HP_0034157', 'url': 'http://purl.obolibrary.org/obo/HP_0034157', 'lbl': 'Anti-beta-2-Glycoprotein I IgM antibody positivity', 'desc': 'label: Anti-beta-2-Glycoprotein I IgM antibody positivity\ndefinition : Presence of IgM antibodies against beta 2 glycoprotein I in the circulation. Beta-2 glycoprotein I (beta2GPI) is the principal target of autoantibodies in the antiphospholipid syndrome.\nsynonyms :Anti-beta2GPI IgM antibody positivity\n'}


{'id': 'HP_0034158', 'url': 'http://purl.obolibrary.org/obo/HP_0034158', 'lbl': 'Anti-tyrosine phosphatase region of islet antigen-2 antibody positivity', 'desc': 'label: Anti-tyrosine phosphatase region of islet antigen-2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against the tyrosine phossphatase region of islet antigen 2A (this region is a specific part of IA-2). Usually IA-2A are measured using the intracellular portion of IA-2 (IA-2ic) made up of the protein tyrosine phosphatase (PTP) and juxtamembrane (JM) regions.\nsynonyms :Anti-PTPA antibody positivity\n'}


{'id': 'HP_0034159', 'url': 'http://purl.obolibrary.org/obo/HP_0034159', 'lbl': 'Paget disease of bone', 'desc': 'label: Paget disease of bone\ndefinition : A localized disorder of bone remodeling. Increased numbers of larger than normal osteoclasts initiate the process at affected skeletal sites, and the increase in bone resorption is followed by an increase in new bone formation, altering bone architecture.\nsynonyms :\n'}


{'id': 'HP_0034160', 'url': 'http://purl.obolibrary.org/obo/HP_0034160', 'lbl': 'Abnormal circulating interleukin 9 concentration', 'desc': 'label: Abnormal circulating interleukin 9 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 9 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034161', 'url': 'http://purl.obolibrary.org/obo/HP_0034161', 'lbl': 'Reduced circulating interleukin 9 concentration', 'desc': 'label: Reduced circulating interleukin 9 concentration\ndefinition : An abnormally decreased concentration of interleukin 9 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034162', 'url': 'http://purl.obolibrary.org/obo/HP_0034162', 'lbl': 'Abnormal circulating interleukin 10 concentration', 'desc': 'label: Abnormal circulating interleukin 10 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 10 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034163', 'url': 'http://purl.obolibrary.org/obo/HP_0034163', 'lbl': 'Reduced circulating interleukin 10 concentration', 'desc': 'label: Reduced circulating interleukin 10 concentration\ndefinition : An abnormally decreased concentration of interleukin 10 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034164', 'url': 'http://purl.obolibrary.org/obo/HP_0034164', 'lbl': 'Abnormal circulating interleukin 21 concentration', 'desc': 'label: Abnormal circulating interleukin 21 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 21 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034165', 'url': 'http://purl.obolibrary.org/obo/HP_0034165', 'lbl': 'Reduced circulating interleukin 21 concentration', 'desc': 'label: Reduced circulating interleukin 21 concentration\ndefinition : An abnormally decreased concentration of interleukin 21 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034166', 'url': 'http://purl.obolibrary.org/obo/HP_0034166', 'lbl': 'Increased circulating interleukin 21 concentration', 'desc': 'label: Increased circulating interleukin 21 concentration\ndefinition : An abnormally increased concentration of interleukin 21 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034167', 'url': 'http://purl.obolibrary.org/obo/HP_0034167', 'lbl': 'Abnormal circulating interleukin 22 concentration', 'desc': 'label: Abnormal circulating interleukin 22 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 22 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034168', 'url': 'http://purl.obolibrary.org/obo/HP_0034168', 'lbl': 'Reduced circulating interleukin 22 concentration', 'desc': 'label: Reduced circulating interleukin 22 concentration\ndefinition : An abnormally decreased concentration of interleukin 22 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034169', 'url': 'http://purl.obolibrary.org/obo/HP_0034169', 'lbl': 'Increased circulating interleukin 22 concentration', 'desc': 'label: Increased circulating interleukin 22 concentration\ndefinition : An abnormally increased concentration of interleukin 22 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034170', 'url': 'http://purl.obolibrary.org/obo/HP_0034170', 'lbl': 'Abnormal circulating interleukin 23 concentration', 'desc': 'label: Abnormal circulating interleukin 23 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 23 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034171', 'url': 'http://purl.obolibrary.org/obo/HP_0034171', 'lbl': 'Reduced circulating interleukin 23 concentration', 'desc': 'label: Reduced circulating interleukin 23 concentration\ndefinition : An abnormally decreased concentration of interleukin 23 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034172', 'url': 'http://purl.obolibrary.org/obo/HP_0034172', 'lbl': 'Increased circulating interleukin 23 concentration', 'desc': 'label: Increased circulating interleukin 23 concentration\ndefinition : An abnormally increased concentration of interleukin 23 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034173', 'url': 'http://purl.obolibrary.org/obo/HP_0034173', 'lbl': 'Abnormal circulating interleukin 27 concentration', 'desc': 'label: Abnormal circulating interleukin 27 concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 27 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034174', 'url': 'http://purl.obolibrary.org/obo/HP_0034174', 'lbl': 'Reduced circulating interleukin 27 concentration', 'desc': 'label: Reduced circulating interleukin 27 concentration\ndefinition : An abnormally decreased concentration of interleukin 27 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034175', 'url': 'http://purl.obolibrary.org/obo/HP_0034175', 'lbl': 'Increased circulating interleukin 27 concentration', 'desc': 'label: Increased circulating interleukin 27 concentration\ndefinition : An abnormally increased concentration of interleukin 27 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034176', 'url': 'http://purl.obolibrary.org/obo/HP_0034176', 'lbl': 'Abnormal circulating interleukin 17A concentration', 'desc': 'label: Abnormal circulating interleukin 17A concentration\ndefinition : Any deviation from the normal range of the concentration of interleukin 17A in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034177', 'url': 'http://purl.obolibrary.org/obo/HP_0034177', 'lbl': 'Reduced circulating interleukin 17A concentration', 'desc': 'label: Reduced circulating interleukin 17A concentration\ndefinition : An abnormally decreased concentration of interleukin 17A in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034178', 'url': 'http://purl.obolibrary.org/obo/HP_0034178', 'lbl': 'Increased circulating interleukin 17A concentration', 'desc': 'label: Increased circulating interleukin 17A concentration\ndefinition : An abnormally increased concentration of interleukin 17A in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034179', 'url': 'http://purl.obolibrary.org/obo/HP_0034179', 'lbl': 'Vertebral artery aneurysm', 'desc': 'label: Vertebral artery aneurysm\ndefinition : Abnormal outpouching or sac-like dilatation in the wall of the vertebral artery .\nsynonyms :\n'}


{'id': 'HP_0034180', 'url': 'http://purl.obolibrary.org/obo/HP_0034180', 'lbl': 'Fusion of the caudate and putamen', 'desc': 'label: Fusion of the caudate and putamen\ndefinition : Abnormal joined appearance of the caudate and putamen with an absence of the anterior limb of the internal capsule.\nsynonyms :\n'}


{'id': 'HP_0034181', 'url': 'http://purl.obolibrary.org/obo/HP_0034181', 'lbl': 'Aplasia/Hypoplasia of the liver', 'desc': 'label: Aplasia/Hypoplasia of the liver\ndefinition : Absence or underdevelopment of the liver.\nsynonyms :\n'}


{'id': 'HP_0034182', 'url': 'http://purl.obolibrary.org/obo/HP_0034182', 'lbl': 'Segmental hypoplasia of liver', 'desc': 'label: Segmental hypoplasia of liver\ndefinition : Anatomically the liver is divided into right and left lobes based on the attachment of its peritoneal ligaments. This term refers to a developmental anomaly characterzied by the underdevelopment of one of the lobes of the liver. This is a rare and usually asymptomatic anomaly that can be detected incidentally on cross sectional imaging with computed tomography or magnetic resonance imaging.\nsynonyms :\n'}


{'id': 'HP_0034183', 'url': 'http://purl.obolibrary.org/obo/HP_0034183', 'lbl': 'Spastic triplegia', 'desc': 'label: Spastic triplegia\ndefinition : Spastic weakness found in both lower extremities and one upper extremity.\nsynonyms :\n'}


{'id': 'HP_0034184', 'url': 'http://purl.obolibrary.org/obo/HP_0034184', 'lbl': 'Increased insulin like growth factor binding protein acid labile subunit concentration', 'desc': 'label: Increased insulin like growth factor binding protein acid labile subunit concentration\ndefinition : An abnormally elevated concentration of insulin like growth factor binding protein acid labile subunit level in the blood circulation.\nsynonyms :Increased circulating IGFALS contration\n'}


{'id': 'HP_0034185', 'url': 'http://purl.obolibrary.org/obo/HP_0034185', 'lbl': 'Median pseudocleft lip', 'desc': 'label: Median pseudocleft lip\ndefinition : A type of mild median cleft lip in which the central tubercle of the upper lip is replaced by a mucosal cleft in the midline.\nsynonyms :\n'}


{'id': 'HP_0034186', 'url': 'http://purl.obolibrary.org/obo/HP_0034186', 'lbl': 'Patella alta', 'desc': 'label: Patella alta\ndefinition : Patella alta is a patella that rides abnormally high in relation to the femur, the femoral trochlea, or the tibia, with decreased bony stability requiring increased knee flexion angles to engage the trochlea.\nsynonyms :\n'}


{'id': 'HP_0034187', 'url': 'http://purl.obolibrary.org/obo/HP_0034187', 'lbl': 'Clavicular pseudarthrosis', 'desc': 'label: Clavicular pseudarthrosis\ndefinition : A developmental defect in a the clavicule leading to bending and pathologic fracture, with inability to form a normal bony callus with subsequent fibrous nonunion, leading to the pseudarthrosis (or false joint).\nsynonyms :\n'}


{'id': 'HP_0034188', 'url': 'http://purl.obolibrary.org/obo/HP_0034188', 'lbl': 'Midline liver', 'desc': 'label: Midline liver\ndefinition : Position of the liver across the middle of the body instead of being in its normal position to the right of the stomach.\nsynonyms :\n'}


{'id': 'HP_0034189', 'url': 'http://purl.obolibrary.org/obo/HP_0034189', 'lbl': 'Anti-thyroid-stimulating hormone receptor antibody positivity', 'desc': 'label: Anti-thyroid-stimulating hormone receptor antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against thyroid-stimulating hormone.\nsynonyms :Anti-TSH receptor antibody positivity; TRAbs\n'}


{'id': 'HP_0034190', 'url': 'http://purl.obolibrary.org/obo/HP_0034190', 'lbl': 'Abnormal fetal cardiovascular physiology', 'desc': 'label: Abnormal fetal cardiovascular physiology\ndefinition : Abnormal functionality of the fetal cardiovascular system.\nsynonyms :\n'}


{'id': 'HP_0034191', 'url': 'http://purl.obolibrary.org/obo/HP_0034191', 'lbl': 'Elevated fetal middle cerebral artery peak systolic velocity', 'desc': 'label: Elevated fetal middle cerebral artery peak systolic velocity\ndefinition : Increased peak systolic velocity of the fetal middle cerebral artery (MCA) as evaluated by Doppler ultrasound.\nsynonyms :\n'}


{'id': 'HP_0034192', 'url': 'http://purl.obolibrary.org/obo/HP_0034192', 'lbl': 'Pulmonary thromboembolism', 'desc': 'label: Pulmonary thromboembolism\ndefinition : Pulmonary embolism is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung.\nsynonyms :\n'}


{'id': 'HP_0034193', 'url': 'http://purl.obolibrary.org/obo/HP_0034193', 'lbl': 'Stratum basale cleavage', 'desc': 'label: Stratum basale cleavage\ndefinition : Cleavage within the epidermal keratinocytes, which is the innermost layer of the epidermis and consists of proliferating cells that give rise to the outer layers of the epidermis.\nsynonyms :Blistering with cleavage within basal keratinocytes; Cleavage within the basal keratinocyte layer\n'}


{'id': 'HP_0034194', 'url': 'http://purl.obolibrary.org/obo/HP_0034194', 'lbl': 'Suprabasal cleavage', 'desc': 'label: Suprabasal cleavage\ndefinition : Cleavage within the suprabasal cell layer of the epidermis, which lies directly above the basal layer and is composed of five to ten layers of cells.\nsynonyms :Blistering with suprabasal clefting\n'}


{'id': 'HP_0034195', 'url': 'http://purl.obolibrary.org/obo/HP_0034195', 'lbl': 'Triggered by muscle relaxant', 'desc': 'label: Triggered by muscle relaxant\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to a muscle relaxant such as suxamethonium and mivacurium.\nsynonyms :\n'}


{'id': 'HP_0034196', 'url': 'http://purl.obolibrary.org/obo/HP_0034196', 'lbl': 'Ductus venosus agenesis', 'desc': 'label: Ductus venosus agenesis\ndefinition : A developmental defect characterized by lack of formation of the ductus venosus (a shunt that allows oxygenated blood in the umbilical vein to bypass the liver in the fetal circulation).\nsynonyms :Agenesis of the ductus venosus\n'}


{'id': 'HP_0034197', 'url': 'http://purl.obolibrary.org/obo/HP_0034197', 'lbl': 'Third trimester onset', 'desc': 'label: Third trimester onset\ndefinition : This term refers to a phenotypic feature that was first observed prior to birth during the third trimester, which is defined as 28 weeks and zero days (28+0) of gestation and beyond.\nsynonyms :\n'}


{'id': 'HP_0034198', 'url': 'http://purl.obolibrary.org/obo/HP_0034198', 'lbl': 'Second trimester onset', 'desc': 'label: Second trimester onset\ndefinition : This term refers to a phenotypic feature that was first observed prior to birth during the second trimester, which comprises the range of gestational ages from 14 0/7 weeks to 27 6/7 (inclusive).\nsynonyms :\n'}


{'id': 'HP_0034199', 'url': 'http://purl.obolibrary.org/obo/HP_0034199', 'lbl': 'Late first trimester onset', 'desc': 'label: Late first trimester onset\ndefinition : This term refers to a phenotypic feature that was first observed prior to birth in the first trimester during the early fetal period, which is defined as 11 0/7 to 13 6/7 weeks of gestation (inclusive).\nsynonyms :Early fetal onset\n'}


{'id': 'HP_0034200', 'url': 'http://purl.obolibrary.org/obo/HP_0034200', 'lbl': 'Abnormal CSF homovanillic acid concentration', 'desc': 'label: Abnormal CSF homovanillic acid concentration\ndefinition : Any deviation from the normal concentration of homovanillic acid (HVA) in the cerebrospinal fluid. HVA is a metabolite of dopamine.\nsynonyms :\n'}


{'id': 'HP_0034201', 'url': 'http://purl.obolibrary.org/obo/HP_0034201', 'lbl': 'Increased CSF homovanillic acid concentration', 'desc': 'label: Increased CSF homovanillic acid concentration\ndefinition : Elevated concentration of homovanillic acid (HVA) in the cerebrospinal fluid. HVA is a metabolite of dopamine.\nsynonyms :\n'}


{'id': 'HP_0034202', 'url': 'http://purl.obolibrary.org/obo/HP_0034202', 'lbl': 'Abnormal iduronate sulfatase concentration', 'desc': 'label: Abnormal iduronate sulfatase concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0034203', 'url': 'http://purl.obolibrary.org/obo/HP_0034203', 'lbl': 'Decreased iduronate sulfatase level', 'desc': 'label: Decreased iduronate sulfatase level\ndefinition : An decreased level of iduronate-2-sulfatase activity in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034204', 'url': 'http://purl.obolibrary.org/obo/HP_0034204', 'lbl': 'Decreased circulating C1-esterase inhibitor concentration', 'desc': 'label: Decreased circulating C1-esterase inhibitor concentration\ndefinition : Decreased concentration of C1-esterase inhibitor (C1INH) in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0034205', 'url': 'http://purl.obolibrary.org/obo/HP_0034205', 'lbl': 'Iniencephaly', 'desc': 'label: Iniencephaly\ndefinition : Iniencephaly is a rare neural tube defect involving dysmorphic spine and abnormal fusion of the portion of the occipital skull with the back. It results in extreme fixed head retroflexion.\nsynonyms :\n'}


{'id': 'HP_0034206', 'url': 'http://purl.obolibrary.org/obo/HP_0034206', 'lbl': 'Abnormal fetal central nervous system morphology', 'desc': 'label: Abnormal fetal central nervous system morphology\ndefinition : An anomalous structural finding of the fetal central nervous system. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes.\nsynonyms :Abnormal fetal CNS morphology\n'}


{'id': 'HP_0034207', 'url': 'http://purl.obolibrary.org/obo/HP_0034207', 'lbl': 'Abnormal fetal gastrointestinal system morphology', 'desc': 'label: Abnormal fetal gastrointestinal system morphology\ndefinition : An anomalous structural finding of the fetal gastrointestinal system. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes.\nsynonyms :\n'}


{'id': 'HP_0034208', 'url': 'http://purl.obolibrary.org/obo/HP_0034208', 'lbl': 'Fetal intracranial hemorrhage', 'desc': 'label: Fetal intracranial hemorrhage\ndefinition : Abnormal bleeding inside the skull (cranium) of a fetus.\nsynonyms :\n'}


{'id': 'HP_0034209', 'url': 'http://purl.obolibrary.org/obo/HP_0034209', 'lbl': 'Fetal subependymal hemorrhage', 'desc': 'label: Fetal subependymal hemorrhage\ndefinition : A type of fetal intracranial hemorrhage located in the subependymal germinal matrix below the frontal horns of the lateral ventricles in the caudothalamic notch.\nsynonyms :Grade I fetal intracranial hemorrhage\n'}


{'id': 'HP_0034210', 'url': 'http://purl.obolibrary.org/obo/HP_0034210', 'lbl': 'Fetal intraventricular hemorrhage', 'desc': 'label: Fetal intraventricular hemorrhage\ndefinition : A type of fetal intracranial hemorrhage with bleeding into the ventricular system of the brain.\nsynonyms :\n'}


{'id': 'HP_0034211', 'url': 'http://purl.obolibrary.org/obo/HP_0034211', 'lbl': 'Fetal cerebral parenchymal hemorrhage', 'desc': 'label: Fetal cerebral parenchymal hemorrhage\ndefinition : A type of fetal intracranial hemorrhage with bleeding into the parenchyma (tissue) of the brain.\nsynonyms :\n'}


{'id': 'HP_0034212', 'url': 'http://purl.obolibrary.org/obo/HP_0034212', 'lbl': 'Fetal extra-axial hemorrhage', 'desc': 'label: Fetal extra-axial hemorrhage\ndefinition : A type of fetal intracranial hemorrhage with bleeding that occurs within the skull but outside of the brain tissue itself (into the epidural, subdural, or arachnoid space).\nsynonyms :\n'}


{'id': 'HP_0034213', 'url': 'http://purl.obolibrary.org/obo/HP_0034213', 'lbl': 'Fetal posterior fossa hemorrhage', 'desc': 'label: Fetal posterior fossa hemorrhage\ndefinition : A type of fetal intracranial hemorrhage that occurs in the posterior cranial fossa, which is the part of the cranial cavity that is located between the foramen magnum and tentorium cerebelli and contains the brainstem and cerebellum.\nsynonyms :\n'}


{'id': 'HP_0034214', 'url': 'http://purl.obolibrary.org/obo/HP_0034214', 'lbl': 'Fetal intraventricular hemorrhage without ventriculomegaly', 'desc': 'label: Fetal intraventricular hemorrhage without ventriculomegaly\ndefinition : A type of fetal intraventricular hemorrhage characterized by clear hemorrhage spillover to the ventricles filling less than 50% of the lateral ventricle and without ventriculomegaly of greater than 15 mm in the transverse diameter of the lateral ventricular atrium.\nsynonyms :Grade II fetal intracranial hemorrhage\n'}


{'id': 'HP_0034215', 'url': 'http://purl.obolibrary.org/obo/HP_0034215', 'lbl': 'Fetal cerebellar hemisphere hemorrhage', 'desc': 'label: Fetal cerebellar hemisphere hemorrhage\ndefinition : A type of fetal intracranial hemorrhage that occurs in the hemisphere of the cerebellum.\nsynonyms :\n'}


{'id': 'HP_0034216', 'url': 'http://purl.obolibrary.org/obo/HP_0034216', 'lbl': 'Fetal cerebellar vermis hemorrhage', 'desc': 'label: Fetal cerebellar vermis hemorrhage\ndefinition : A type of fetal intracranial hemorrhage that occurs in the vermis of the cerebellum.\nsynonyms :\n'}


{'id': 'HP_0034217', 'url': 'http://purl.obolibrary.org/obo/HP_0034217', 'lbl': 'Sonographic non-visualized fetal bladder', 'desc': 'label: Sonographic non-visualized fetal bladder\ndefinition : Inability to visualize the fetal bladder on targeted prenatal sonography examination. The fetal bladder can be visualized with sonography as a midline, fluid-filled structure in the pelvis as early as 10-12 weeks of gestation. The normal fetus voids at least once an hour but never completely empties the urinary bladder. The fetal bladdder should be consistently imaged after 13 weeks of gestation.\nsynonyms :\n'}


{'id': 'HP_0034218', 'url': 'http://purl.obolibrary.org/obo/HP_0034218', 'lbl': 'Fetal intraventricular hemorrhage with ventriculomegaly', 'desc': 'label: Fetal intraventricular hemorrhage with ventriculomegaly\ndefinition : A type of fetal intraventricular hemorrhage (IVH) characterized by spillover to ventricles with flooding of 50% or more of one or both lateral ventricles accrued accompanying ventriculomegaly, but with no apparent brain parenchymal injury. This type of IVH may be defined as a diameter exceeding 15 mm in the transverse diameter of the lateral ventricular atrium as visualiuzed by prenatal sonography.\nsynonyms :Grade III fetal intracranial hemorrhage\n'}


{'id': 'HP_0034219', 'url': 'http://purl.obolibrary.org/obo/HP_0034219', 'lbl': 'Fetal intraventricular hemorrhage with periventricular hemorrhage', 'desc': 'label: Fetal intraventricular hemorrhage with periventricular hemorrhage\ndefinition : A type of fetal intraventricular hemorrhage that additionally includes hemorrhage in a large part of the periventricular parenchyma.\nsynonyms :Grade IV fetal intracranial hemorrhage\n'}


{'id': 'HP_0034220', 'url': 'http://purl.obolibrary.org/obo/HP_0034220', 'lbl': 'Temporal lobe megalencephaly', 'desc': 'label: Temporal lobe megalencephaly\ndefinition : Expansion of the temporal lobes of the brain along all axes, including rostrocaudal, superoinferior, and mediolateral, resulting in a globular appearance of the brain.\nsynonyms :\n'}