{'id': 'HP_0032111', 'url': 'http://purl.obolibrary.org/obo/HP_0032111', 'lbl': 'Abnormal Vistech contrast sensitivity test', 'desc': 'label: Abnormal Vistech contrast sensitivity test\ndefinition : An abnormality in perception of contrast as measured by the Vistech wall chart sine wave grating test.\nsynonyms :\n'}


{'id': 'HP_0032112', 'url': 'http://purl.obolibrary.org/obo/HP_0032112', 'lbl': 'Abnormal Pelli Robson contrast sensitivity chart test', 'desc': 'label: Abnormal Pelli Robson contrast sensitivity chart test\ndefinition : An abnormality in perception of contrast as measured by the Pelli-Robson contrast sensitivity chart, which is a large wall-mounted chart, with letters of a fixed size (comprising spatial frequencies appropriate for estimating peak contrast sensitivity) that decrease in contrast.\nsynonyms :\n'}


{'id': 'HP_0032113', 'url': 'http://purl.obolibrary.org/obo/HP_0032113', 'lbl': 'Semidominant inheritance', 'desc': 'label: Semidominant inheritance\ndefinition : A mode of inheritance that is observed for traits related to a gene encoded on chromosomes in which a trait can manifest in a monoallelic (e.g. heterozygotes) and biallelic (e.g. homozygotes, compound heterozygotes) state, with similar or differing phenotype severity present dependent on the number of alleles affected.\nsynonyms :Semidominant mode of inheritance\n'}


{'id': 'HP_0032114', 'url': 'http://purl.obolibrary.org/obo/HP_0032114', 'lbl': 'Saccadic intrusion', 'desc': 'label: Saccadic intrusion\ndefinition : An involuntary abnormality of fixation in which there is an abnormal saccade away from fixation followed by a delayed corrective saccade.\nsynonyms :\n'}


{'id': 'HP_0032116', 'url': 'http://purl.obolibrary.org/obo/HP_0032116', 'lbl': 'Macrosquare-wave jerks', 'desc': 'label: Macrosquare-wave jerks\ndefinition : Horizontal 10-40 degree excursions from fixation and back again.\nsynonyms :\n'}


{'id': 'HP_0032117', 'url': 'http://purl.obolibrary.org/obo/HP_0032117', 'lbl': 'obsolete Macrosaccadic oscillation', 'desc': 'label: obsolete Macrosaccadic oscillation\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032118', 'url': 'http://purl.obolibrary.org/obo/HP_0032118', 'lbl': 'Retinitis', 'desc': 'label: Retinitis\ndefinition : Inflammation of the retina of the eye.\nsynonyms :\n'}


{'id': 'HP_0032119', 'url': 'http://purl.obolibrary.org/obo/HP_0032119', 'lbl': 'obsolete Narrow angle glaucoma', 'desc': 'label: obsolete Narrow angle glaucoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032120', 'url': 'http://purl.obolibrary.org/obo/HP_0032120', 'lbl': 'Abnormal peripheral nervous system physiology', 'desc': 'label: Abnormal peripheral nervous system physiology\ndefinition : Any functional abnormality of the part of the nervous system that consists of the nerves and ganglia outside of the brain and spinal cord.\nsynonyms :\n'}


{'id': 'HP_0032121', 'url': 'http://purl.obolibrary.org/obo/HP_0032121', 'lbl': 'Froment sign', 'desc': 'label: Froment sign\ndefinition : An abnormal result of a physical examination of the the hand that tests for palsy of the ulnar nerve. This nerve innervates the adductor pollicis and interossei muscles and thereby enables adduction of the thumb and extension of the interphalangeal joint. An abnormal result consists in reduced functionality and muscular weakness in the pinch grip between the thumb and index finger of the affected hand as the patient attempts to pinch a piece of paper that the examiner tries to pull away. The flexor pollicis longus muscle tries to compensate for the weakness by flexing the tip of the thumb at the interphalangeal joint.\nsynonyms :Froment thumb sign\n'}


{'id': 'HP_0032122', 'url': 'http://purl.obolibrary.org/obo/HP_0032122', 'lbl': 'Very low visual acuity', 'desc': 'label: Very low visual acuity\ndefinition : A reduction in visual acuity with best corrected visual acuity between 1.40 (20/500) and 1.89 logMAR (up to roughly 20/1590).\nsynonyms :\n'}


{'id': 'HP_0032123', 'url': 'http://purl.obolibrary.org/obo/HP_0032123', 'lbl': 'Ultra-low vision', 'desc': 'label: Ultra-low vision\ndefinition : Best corrected visual acuity worse than 1.90 logMAR (roughly 20/1590).\nsynonyms :\n'}


{'id': 'HP_0032124', 'url': 'http://purl.obolibrary.org/obo/HP_0032124', 'lbl': 'Abnormal proportion of unswitched memory B cells', 'desc': 'label: Abnormal proportion of unswitched memory B cells\ndefinition : A deviation of the normal proportion of unswitched memory B cells in circulation relative to the total number of B cells.\nsynonyms :Abnormal proportion of non-class-switched memory B cells\n'}


{'id': 'HP_0032125', 'url': 'http://purl.obolibrary.org/obo/HP_0032125', 'lbl': 'Increased proportion of unswitched memory B cells', 'desc': 'label: Increased proportion of unswitched memory B cells\ndefinition : An increase above the normal proportion of non-class-switched memory B cells relative to the total number of B cells.\nsynonyms :Elevated proportion of unswitched memory B cells; Increased proportion of non-class-switched memory B cells\n'}


{'id': 'HP_0032126', 'url': 'http://purl.obolibrary.org/obo/HP_0032126', 'lbl': 'Decreased proportion of unswitched memory B cells', 'desc': 'label: Decreased proportion of unswitched memory B cells\ndefinition : A reduction below the normal proportion of non-class-switched memory B cells relative to the total number of B cells.\nsynonyms :Decreased proportion of non-class-switched memory B cells; Reduced proportion of unswitched memory B cells\n'}


{'id': 'HP_0032127', 'url': 'http://purl.obolibrary.org/obo/HP_0032127', 'lbl': 'Abnormal plasmablast proportion', 'desc': 'label: Abnormal plasmablast proportion\ndefinition : A deviation from the normal proportion of plasmablasts in circulation relative to total number of B cells. Plasmablasts are antibody-secreting cells that originate after infection or vaccination.\nsynonyms :\n'}


{'id': 'HP_0032128', 'url': 'http://purl.obolibrary.org/obo/HP_0032128', 'lbl': 'Increased proportion of plasmablasts', 'desc': 'label: Increased proportion of plasmablasts\ndefinition : An elevation above the normal proportion of plasmablasts in circulation relative to total number of B cells.\nsynonyms :\n'}


{'id': 'HP_0032129', 'url': 'http://purl.obolibrary.org/obo/HP_0032129', 'lbl': 'Decreased proportion of plasmablasts', 'desc': 'label: Decreased proportion of plasmablasts\ndefinition : A reduction below the normal proportion of plasmablasts in circulation relative to total number of B cells.\nsynonyms :\n'}


{'id': 'HP_0032130', 'url': 'http://purl.obolibrary.org/obo/HP_0032130', 'lbl': 'Mycobacterium abscessus abscessus infection', 'desc': 'label: Mycobacterium abscessus abscessus infection\ndefinition : Mycobacterium abscessus complex comprises a group of rapidly growing, multidrug-resistant, nontuberculous mycobacteria that are responsible for a wide spectrum of skin and soft tissue diseases, central nervous system infections, bacteremia, and ocular and other infections.\nsynonyms :\n'}


{'id': 'HP_0032131', 'url': 'http://purl.obolibrary.org/obo/HP_0032131', 'lbl': 'Cervical dysplasia', 'desc': 'label: Cervical dysplasia\ndefinition : Cervical dysplasia is the precursor to cervical cancer. It is caused by the persistent infection of the human papillomavirus (HPV) into the cervical tissue. Affected cells develop morphologic features with immature basaloid- type squamous cells and mitotic figures in the upper half of the cervical epithelium.\nsynonyms :Uterine cervix dysplasia\n'}


{'id': 'HP_0032132', 'url': 'http://purl.obolibrary.org/obo/HP_0032132', 'lbl': 'Decreased circulating total IgG', 'desc': 'label: Decreased circulating total IgG\ndefinition : A reduction beneath the normal level of total immunoglobulin G (IgG) in the blood.\nsynonyms :\n'}


{'id': 'HP_0032133', 'url': 'http://purl.obolibrary.org/obo/HP_0032133', 'lbl': 'Transient decreased circulating total IgG', 'desc': 'label: Transient decreased circulating total IgG\ndefinition : A temporary reduction beneath the normal level of total immunoglobulin G (IgG) in the blood.\nsynonyms :\n'}


{'id': 'HP_0032134', 'url': 'http://purl.obolibrary.org/obo/HP_0032134', 'lbl': 'Chronic decreased circulating total IgG', 'desc': 'label: Chronic decreased circulating total IgG\ndefinition : A lasting reduction beneath the normal level of total immunoglobulin G (IgG) in the blood.\nsynonyms :Chronic decreased total IgG in blood\n'}


{'id': 'HP_0032135', 'url': 'http://purl.obolibrary.org/obo/HP_0032135', 'lbl': 'Decreased circulating IgG subclass level', 'desc': 'label: Decreased circulating IgG subclass level\ndefinition : A reduction below the normal concentration of a subclass of immunoglobulin G (IgG) in the blood.\nsynonyms :Decreased IgG subclass level in blood\n'}


{'id': 'HP_0032136', 'url': 'http://purl.obolibrary.org/obo/HP_0032136', 'lbl': 'Decreased circulating IgG1 level', 'desc': 'label: Decreased circulating IgG1 level\ndefinition : A reduction in immunoglobulin levels of the IgG1 subclass in the blood circulation.\nsynonyms :Decreased IgG1 level in blood\n'}


{'id': 'HP_0032137', 'url': 'http://purl.obolibrary.org/obo/HP_0032137', 'lbl': 'Decreased circulating IgG3 level', 'desc': 'label: Decreased circulating IgG3 level\ndefinition : A reduction in immunoglobulin levels of the IgG3 subclass in the blood circulation.\nsynonyms :Decreased IgG3 level in blood\n'}


{'id': 'HP_0032138', 'url': 'http://purl.obolibrary.org/obo/HP_0032138', 'lbl': 'Decreased circulating IgG4 level', 'desc': 'label: Decreased circulating IgG4 level\ndefinition : A reduction in immunoglobulin levels of the IgG4 subclass in the blood circulation.\nsynonyms :Decreased IgG4 level in blood\n'}


{'id': 'HP_0032139', 'url': 'http://purl.obolibrary.org/obo/HP_0032139', 'lbl': 'Reduced isohemagglutinin level', 'desc': 'label: Reduced isohemagglutinin level\ndefinition : Level of isohemagglutinin reduced below expected concentration. An isohemagglutinin refers to the naturally occurring antibodies in the ABO blood group system (i.e., anti-A in a group B person, anti-B in a group A person, and anti-A, anti-B, and anti-A,B in a group O person).\nsynonyms :Decreased natural antibody to blood group agents; Partial absence of isohemagglutinins\n'}


{'id': 'HP_0032140', 'url': 'http://purl.obolibrary.org/obo/HP_0032140', 'lbl': 'Decreased specific antibody response to vaccination', 'desc': 'label: Decreased specific antibody response to vaccination\ndefinition : A reduced ability to synthesize postvaccination antibodies against toxoids and polysaccharides in vaccines, as measured by antibody titer determination following vaccination.\nsynonyms :\n'}


{'id': 'HP_0032141', 'url': 'http://purl.obolibrary.org/obo/HP_0032141', 'lbl': 'Precordial pain', 'desc': 'label: Precordial pain\ndefinition : A type of chest pain that arises in the or under the left breast and often described as throbbing, stabbing, or burning, and lasting hours or longer. The pain may arise with or after effort, and may spread to the left arm or left side of the neck.\nsynonyms :\n'}


{'id': 'HP_0032142', 'url': 'http://purl.obolibrary.org/obo/HP_0032142', 'lbl': 'Fetor hepaticus', 'desc': 'label: Fetor hepaticus\ndefinition : Fetor hepaticus is the characteristic breath of patients with severe parenchymal liver disease, which has been said to resemble the odor of a mixture of rotten eggs and garlic.\nsynonyms :Foetor hepaticus\n'}


{'id': 'HP_0032143', 'url': 'http://purl.obolibrary.org/obo/HP_0032143', 'lbl': 'Burning mouth', 'desc': 'label: Burning mouth\ndefinition : An intense sensation of burning, scalding, or tingling feeling of the tongue or other regions of the oral mucosa.\nsynonyms :\n'}


{'id': 'HP_0032144', 'url': 'http://purl.obolibrary.org/obo/HP_0032144', 'lbl': 'Coffee ground vomitus', 'desc': 'label: Coffee ground vomitus\ndefinition : Vomit that has the appearance of coffee grounds, which occurs due to the presence of coagulated blood in the vomit.\nsynonyms :Coffee grounds emesis; Coffee grounds vomiting\n'}


{'id': 'HP_0032145', 'url': 'http://purl.obolibrary.org/obo/HP_0032145', 'lbl': 'Sural nerve atrophy', 'desc': 'label: Sural nerve atrophy\ndefinition : Wasting of the sural nerve, a sensory nerve in the calf region of the leg.\nsynonyms :Atrophy of sural nerve\n'}


{'id': 'HP_0032146', 'url': 'http://purl.obolibrary.org/obo/HP_0032146', 'lbl': 'HbC hemoglobin', 'desc': 'label: HbC hemoglobin\ndefinition : Presence of an abnormal type of hemoglobin characterized by the subsitution of a glutamic acid residue at position 7 following the initial methionine residue by a lysine (6GAG>6AAG). The presence of HbC can be determined by hemoglobin electrophoresis.\nsynonyms :Haemoglobin C; HbC haemoglobin; Hemoglobin C\n'}


{'id': 'HP_0032147', 'url': 'http://purl.obolibrary.org/obo/HP_0032147', 'lbl': 'Erythromelalgia', 'desc': 'label: Erythromelalgia\ndefinition : Recurrent episodes of redness, burning pain, and warmth of the extremities following exposure to heat or exercise with symptoms predominantly involving the feet.\nsynonyms :\n'}


{'id': 'HP_0032148', 'url': 'http://purl.obolibrary.org/obo/HP_0032148', 'lbl': 'Episodic pain', 'desc': 'label: Episodic pain\ndefinition : Intermittent pain, i.e., pain that occurs occasionally and at irregular intervals.\nsynonyms :\n'}


{'id': 'HP_0032149', 'url': 'http://purl.obolibrary.org/obo/HP_0032149', 'lbl': 'Breakthrough pain', 'desc': 'label: Breakthrough pain\ndefinition : A episode of severe pain that breaks through (i.e., temporarily exacerbates) a period of persistent pain.\nsynonyms :\n'}


{'id': 'HP_0032150', 'url': 'http://purl.obolibrary.org/obo/HP_0032150', 'lbl': 'Paroxysmal rectal pain', 'desc': 'label: Paroxysmal rectal pain\ndefinition : Excruciating burning pain in the rectal area that may be triggered by defecation.\nsynonyms :\n'}


{'id': 'HP_0032151', 'url': 'http://purl.obolibrary.org/obo/HP_0032151', 'lbl': 'Episodic eosinophilia', 'desc': 'label: Episodic eosinophilia\ndefinition : Recurrent episodes of marked eosinophilia that resolve spontaneously.\nsynonyms :\n'}


{'id': 'HP_0032152', 'url': 'http://purl.obolibrary.org/obo/HP_0032152', 'lbl': 'Keratosis pilaris', 'desc': 'label: Keratosis pilaris\ndefinition : An anomaly of the hair follicles of the skin that typically presents as small, rough, brown folliculocentric papules distributed over characteristic areas of the skin, particularly the outer-upper arms and thighs.\nsynonyms :Carpet tack sign; Chicken skin; Follicular keratosis; Follicular keratotic plug; Follicular plugging; Hyperkeratosis pilaris; Lichen pilaris\n'}


{'id': 'HP_0032153', 'url': 'http://purl.obolibrary.org/obo/HP_0032153', 'lbl': 'Joint subluxation', 'desc': 'label: Joint subluxation\ndefinition : A partial dislocation of a joint.\nsynonyms :\n'}


{'id': 'HP_0032154', 'url': 'http://purl.obolibrary.org/obo/HP_0032154', 'lbl': 'Aphthous ulcer', 'desc': 'label: Aphthous ulcer\ndefinition : Oral aphthous ulcers typically present as painful, sharply circumscribed fibrin-covered mucosal defects with a hyperemic border.\nsynonyms :Canker sore\n'}


{'id': 'HP_0032155', 'url': 'http://purl.obolibrary.org/obo/HP_0032155', 'lbl': 'Abdominal cramps', 'desc': 'label: Abdominal cramps\ndefinition : A type of abdominal pain characterized by a feeling of contractions and typically fluctuating in intensity.\nsynonyms :\n'}


{'id': 'HP_0032156', 'url': 'http://purl.obolibrary.org/obo/HP_0032156', 'lbl': 'Skin detachment', 'desc': 'label: Skin detachment\ndefinition : Loss of sections of skin either spontaneously or after gentle handling.\nsynonyms :Detached skin; Epidermal detachment; Skin sloughing\n'}


{'id': 'HP_0032157', 'url': 'http://purl.obolibrary.org/obo/HP_0032157', 'lbl': 'Recurrent genital herpes', 'desc': 'label: Recurrent genital herpes\ndefinition : Recurrent episodes of genital herpes, typically characterized by stages of erythema, papules, short-lived vesicles, painful ulcers, and crusts on the skin of the genitals and surrounding area, and that typically resolve over a period of 2 to 3 weeks.\nsynonyms :\n'}


{'id': 'HP_0032158', 'url': 'http://purl.obolibrary.org/obo/HP_0032158', 'lbl': 'Unusual infection by anatomical site', 'desc': 'label: Unusual infection by anatomical site\ndefinition : An unusual infection classified by the affected body part.\nsynonyms :\n'}


{'id': 'HP_0032159', 'url': 'http://purl.obolibrary.org/obo/HP_0032159', 'lbl': 'Fungal meningitis', 'desc': 'label: Fungal meningitis\ndefinition : An infection of the meninges caused by a fungus. Generally, only individuals with deficiencies of the immune system contract fungal meningitis.\nsynonyms :\n'}


{'id': 'HP_0032160', 'url': 'http://purl.obolibrary.org/obo/HP_0032160', 'lbl': 'Cryptococcal meningitis', 'desc': 'label: Cryptococcal meningitis\ndefinition : A type of fungal meningitis caused by an encapsulated yeast that belongs to the genus Cryptococcus. Cryptococcus neoformans and Cryptococcus gattii are responsible for the majority of cases of human cryptococcosis.\nsynonyms :\n'}


{'id': 'HP_0032161', 'url': 'http://purl.obolibrary.org/obo/HP_0032161', 'lbl': 'Coccidioidal meningitis', 'desc': 'label: Coccidioidal meningitis\ndefinition : A type of fungal meningitis caused by dissemination of coccidioides to basilar meninges.\nsynonyms :\n'}


{'id': 'HP_0032162', 'url': 'http://purl.obolibrary.org/obo/HP_0032162', 'lbl': 'Unusual skin infection', 'desc': 'label: Unusual skin infection\ndefinition : A type of infection of the skin that can be regarded as a sign of a pathological susceptibility to infection.\nsynonyms :\n'}


{'id': 'HP_0032163', 'url': 'http://purl.obolibrary.org/obo/HP_0032163', 'lbl': 'Molluscum contagiosum', 'desc': 'label: Molluscum contagiosum\ndefinition : Molluscum contagiosum is a cutaneous viral infection that is commonly observed in both healthy and immunocompromised children. The infection is caused by a member of the Poxviridae family, the molluscum contagiosum virus. Molluscum contagiosum presents as single or multiple small white or flesh-colored papules that typically have a central umbilication. The central umbilication may be difficult to observe in young children and, instead, may bear an appearance similar to an acneiform eruption. The lesions vary in size (from 1 mm to 1 cm in diameter) and are painless, although a subset of patients report pruritus in the area of infection. On average, 11-20 papules appear on the body during the course of infection and generally remains a self-limiting disease. However, in immunosuppressed patients, molluscum contagiosum can be a severe infection with hundreds of lesions developing on the body. Extensive eruption is indicative of an advanced immunodeficiency state.\nsynonyms :\n'}


{'id': 'HP_0032164', 'url': 'http://purl.obolibrary.org/obo/HP_0032164', 'lbl': 'Increased blood folate concentration', 'desc': 'label: Increased blood folate concentration\ndefinition : An elevated circulating concentration of folic acid, which is also known as vitamin B9.\nsynonyms :\n'}


{'id': 'HP_0032165', 'url': 'http://purl.obolibrary.org/obo/HP_0032165', 'lbl': 'Placental mesenchymal dysplasia', 'desc': 'label: Placental mesenchymal dysplasia\ndefinition : Placental mesenchymal dysplasia is a rare anomaly characterized by placentomegaly, dilatation of chorionic vessels and hydropic stem villi with cistern-like formation. It is often clinically mistaken for a partial hydatidiform mole but there is no trophoblastic proliferation. P57 immunohistochemical expression is discordant, showing a normal positive expression in the cytotrophoblastic cells, and loss of expression in the stromal cells.\nsynonyms :\n'}


{'id': 'HP_0032166', 'url': 'http://purl.obolibrary.org/obo/HP_0032166', 'lbl': 'Unusual gastrointestinal infection', 'desc': 'label: Unusual gastrointestinal infection\ndefinition : \nsynonyms :Unusual GI infection\n'}


{'id': 'HP_0032167', 'url': 'http://purl.obolibrary.org/obo/HP_0032167', 'lbl': 'Clostridium difficile enteritis', 'desc': 'label: Clostridium difficile enteritis\ndefinition : An infection of the small intestine (enteritis) by clostridium difficile.\nsynonyms :C. difficile enteritis\n'}


{'id': 'HP_0032168', 'url': 'http://purl.obolibrary.org/obo/HP_0032168', 'lbl': 'Clostridium difficile colitis', 'desc': 'label: Clostridium difficile colitis\ndefinition : An infection of the colon (colitis) by clostridium difficile.\nsynonyms :\n'}


{'id': 'HP_0032169', 'url': 'http://purl.obolibrary.org/obo/HP_0032169', 'lbl': 'Severe infection', 'desc': 'label: Severe infection\ndefinition : A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection.\nsynonyms :Unusual course of infection\n'}


{'id': 'HP_0032170', 'url': 'http://purl.obolibrary.org/obo/HP_0032170', 'lbl': 'Severe varicella zoster infection', 'desc': 'label: Severe varicella zoster infection\ndefinition : An unusually severe form of varicella zoster virus (VZV) infection. In the majority of the cases, especially in children, varicella is a very mild infection characterised by skin lesions, low grade fever and malaise. Severe infection is characterized by manifestions including VZV pneumonia, hepatitis, meningitis, and disseminated varicella.\nsynonyms :\n'}


{'id': 'HP_0032171', 'url': 'http://purl.obolibrary.org/obo/HP_0032171', 'lbl': 'Bladder pain', 'desc': 'label: Bladder pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the urinary bladder. Bladder pain may be more pronounced with a full bladder and relieved upon urination, but this is not always the case.\nsynonyms :\n'}


{'id': 'HP_0032172', 'url': 'http://purl.obolibrary.org/obo/HP_0032172', 'lbl': 'Air crescent sign', 'desc': 'label: Air crescent sign\ndefinition : A crescent of air surrounding a soft-tissue mass in a pulmonary cavity and can be seen in both plain X-ray and CT scan.\nsynonyms :\n'}


{'id': 'HP_0032173', 'url': 'http://purl.obolibrary.org/obo/HP_0032173', 'lbl': 'Continuous diaphragm sign', 'desc': 'label: Continuous diaphragm sign\ndefinition : This sign is seen in pneumomediastinum in which air accumulates between the lower border of the heart and the superior part of the diaphragm, which results in complete visualization of the diaphragm in chest X-ray, hence named continuous diaphragm sign.\nsynonyms :\n'}


{'id': 'HP_0032174', 'url': 'http://purl.obolibrary.org/obo/HP_0032174', 'lbl': 'Tree-in-bud pattern', 'desc': 'label: Tree-in-bud pattern\ndefinition : The tree-in-bud pattern represents centrilobular branching structures that resemble a budding tree. The pattern reflects a spectrum of endo- and peribronchiolar disorders, including mucoid impaction, inflammation, and/or fibrosis (See Figure 70 of PMID:18195376).\nsynonyms :\n'}


{'id': 'HP_0032175', 'url': 'http://purl.obolibrary.org/obo/HP_0032175', 'lbl': 'Signet ring sign', 'desc': 'label: Signet ring sign\ndefinition : This finding is composed of a ring-shaped opacity representing a dilated bronchus in cross section and a smaller adjacent opacity representing its pulmonary artery, with the combination resembling a signet (or pearl) ring. It is the basic sign of bronchiectasis in pulmonary computed tomography imaging.\nsynonyms :\n'}


{'id': 'HP_0032176', 'url': 'http://purl.obolibrary.org/obo/HP_0032176', 'lbl': 'Apical pulmonary opacity', 'desc': 'label: Apical pulmonary opacity\ndefinition : An apical cap is a caplike lesion at the lung apex, usually caused by intrapulmonary and pleural fibrosis pulling down extrapleural fat or possibly by chronic ischemia resulting in hyaline plaque formation on the visceral pleura. The prevalence increases with age. It can also be seen in hematoma resulting from aortic rupture or in other fluid collection associated with infection or tumor, either outside the parietal pleura or loculated within the pleural space.\nsynonyms :Apical cap; Apical pleural thickening\n'}


{'id': 'HP_0032177', 'url': 'http://purl.obolibrary.org/obo/HP_0032177', 'lbl': 'Parenchymal consolidation', 'desc': 'label: Parenchymal consolidation\ndefinition : Consolidation refers to an exudate or other product of disease that replaces alveolar air, rendering the lung solid (as in infective pneumonia).\nsynonyms :\n'}


{'id': 'HP_0032178', 'url': 'http://purl.obolibrary.org/obo/HP_0032178', 'lbl': 'Flaky paint dermatosis', 'desc': 'label: Flaky paint dermatosis\ndefinition : A dermatosis characterized by generalized shiny, enamel-like, hyperpigmented scales in an irregular pattern. The scales may peel or desquamate, rather like old, sun-baked blistered paint, often with areas of underlying hypopigmentation. This has led to the terms peeling paint or flaky paint dermatosis (See the Figure in PMID:24285001).\nsynonyms :Flaky paint skin appearance\n'}


{'id': 'HP_0032179', 'url': 'http://purl.obolibrary.org/obo/HP_0032179', 'lbl': 'Abnormal circulating globulin concentration', 'desc': 'label: Abnormal circulating globulin concentration\ndefinition : An abnormal concentration of globulins in the blood. Albumin makes up more than half of the total protein present in serum. The remaining blood proteins except albumin and fibrinogen (which is not in serum) are referred to as globulins. The globulin fraction includes hundreds of serum proteins including carrier proteins, enzymes, complement, and immunoglobulins. Most of these are synthesized in the liver, although the immunoglobulins are synthesized by plasma cells. Globulins are divided into four groups by electrophoresis. The four fractions are alpha1, alpha2, beta and gamma, depending on their migratory pattern between the anode and the cathode.\nsynonyms :Abnormal circulating globulin level\n'}


{'id': 'HP_0032180', 'url': 'http://purl.obolibrary.org/obo/HP_0032180', 'lbl': 'Abnormal circulating metabolite concentration', 'desc': 'label: Abnormal circulating metabolite concentration\ndefinition : An abnormal level of an analyte measured in the blood.\nsynonyms :\n'}


{'id': 'HP_0032181', 'url': 'http://purl.obolibrary.org/obo/HP_0032181', 'lbl': 'Anomalous hepatic venous drainage into the left atrium', 'desc': 'label: Anomalous hepatic venous drainage into the left atrium\ndefinition : An abnormality of the hepatic veins, which normally drain de-oxygenated blood from the liver into the inferior vena cava, whereby the hepatic veins drain into the left atrium.\nsynonyms :\n'}


{'id': 'HP_0032182', 'url': 'http://purl.obolibrary.org/obo/HP_0032182', 'lbl': 'Abnormal proportion of memory T cells', 'desc': 'label: Abnormal proportion of memory T cells\ndefinition : An abnormal proportion of memory T cells compared to the total number of T cells in the blood. Memory T cells have previously encountered and responded to their cognate antigen and upon a repeated encounter with the antigen can mount a faster and stronger response.\nsynonyms :Abnormal proportion of CD4+CD29+ cells\n'}


{'id': 'HP_0032183', 'url': 'http://purl.obolibrary.org/obo/HP_0032183', 'lbl': 'Decreased proportion of memory T cells', 'desc': 'label: Decreased proportion of memory T cells\ndefinition : An abnormally reduced proportion of memory T cells compared to the total number of T cells in the blood.\nsynonyms :Decreased proportion of CD4+CD29+ cells\n'}


{'id': 'HP_0032184', 'url': 'http://purl.obolibrary.org/obo/HP_0032184', 'lbl': 'Increased proportion of memory T cells', 'desc': 'label: Increased proportion of memory T cells\ndefinition : An abnormally elevated proportion of memory T cells compared to the total number of T cells in the blood.\nsynonyms :Increased proportion of CD4+CD29+ cells\n'}


{'id': 'HP_0032185', 'url': 'http://purl.obolibrary.org/obo/HP_0032185', 'lbl': 'Disseminated molluscum contagiosum', 'desc': 'label: Disseminated molluscum contagiosum\ndefinition : The presense of molluscum contagiosum lesions across multiple areas of the body.\nsynonyms :\n'}


{'id': 'HP_0032186', 'url': 'http://purl.obolibrary.org/obo/HP_0032186', 'lbl': 'Anal neoplasm', 'desc': 'label: Anal neoplasm\ndefinition : A benign or malignant neoplasm that affects the anal canal or anal margin.\nsynonyms :\n'}


{'id': 'HP_0032187', 'url': 'http://purl.obolibrary.org/obo/HP_0032187', 'lbl': 'Anal intraepithelial neoplasia', 'desc': 'label: Anal intraepithelial neoplasia\ndefinition : Anal intraepithelial neoplasia (AIN) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer.\nsynonyms :\n'}


{'id': 'HP_0032188', 'url': 'http://purl.obolibrary.org/obo/HP_0032188', 'lbl': 'Cellular hypersensitivity to mitomycin C', 'desc': 'label: Cellular hypersensitivity to mitomycin C\ndefinition : An increased cellular sensitivity to the DNA cross-linking agent, mitomycin C (MMC). In the presence of increased sensitivity, MMC causes increased cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle.\nsynonyms :\n'}


{'id': 'HP_0032189', 'url': 'http://purl.obolibrary.org/obo/HP_0032189', 'lbl': 'Cellular hypersensitivity to diepoxybutane', 'desc': 'label: Cellular hypersensitivity to diepoxybutane\ndefinition : An increased cellular sensitivity to the DNA cross-linking agent, diepoxybutane (DEB). In the presence of increased sensitivity, DEB causes cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle.\nsynonyms :\n'}


{'id': 'HP_0032190', 'url': 'http://purl.obolibrary.org/obo/HP_0032190', 'lbl': 'Abnormal meniscus morphology', 'desc': 'label: Abnormal meniscus morphology\ndefinition : Abnormal structure of the meniscus of the knee, two crescent shape fibrocartilaginous pads that disperse the weight of the body and reduce friction of the knee joint during movement.\nsynonyms :\n'}


{'id': 'HP_0032191', 'url': 'http://purl.obolibrary.org/obo/HP_0032191', 'lbl': 'Torn meniscus', 'desc': 'label: Torn meniscus\ndefinition : A tear in the cartilaginous pad (meniscus) of the knee.\nsynonyms :\n'}


{'id': 'HP_0032192', 'url': 'http://purl.obolibrary.org/obo/HP_0032192', 'lbl': 'Hydatidiform mole', 'desc': 'label: Hydatidiform mole\ndefinition : Hydatidiform mole (HM) is an aberrant human pregnancy with absence of, or abnormal embryonic development, hydropic degeneration of chorionic villi, and excessive proliferation of the trophoblast.\nsynonyms :\n'}


{'id': 'HP_0032193', 'url': 'http://purl.obolibrary.org/obo/HP_0032193', 'lbl': 'Decreased low-density lipoprotein particle size', 'desc': 'label: Decreased low-density lipoprotein particle size\ndefinition : An abnormal decrease in the average size of low-density lipoprotein particle size in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032195', 'url': 'http://purl.obolibrary.org/obo/HP_0032195', 'lbl': 'Abnormal S wave', 'desc': 'label: Abnormal S wave\ndefinition : Any anomaly of the S wave, which is the third component of the QRS wave complex. The S wave signifies the final depolarization of the ventricles at the base of the heart.\nsynonyms :\n'}


{'id': 'HP_0032196', 'url': 'http://purl.obolibrary.org/obo/HP_0032196', 'lbl': 'Prominent S wave in lead I', 'desc': 'label: Prominent S wave in lead I\ndefinition : Increased amplitude (0.1 mV or more) and/or duration (40 ms or more) of the S wave as measured in lead I of the electrocardiogram.\nsynonyms :\n'}


{'id': 'HP_0032197', 'url': 'http://purl.obolibrary.org/obo/HP_0032197', 'lbl': 'Deep S wave in lead V5', 'desc': 'label: Deep S wave in lead V5\ndefinition : Abnormal depth of the S wave in lead V5 of the electrocardiogram.\nsynonyms :\n'}


{'id': 'HP_0032198', 'url': 'http://purl.obolibrary.org/obo/HP_0032198', 'lbl': 'Decreased prothrombin time', 'desc': "label: Decreased prothrombin time\ndefinition : Abnormally short time to coagulation in the prothrombin time test, which is a measure of the extrinsic pathway of coagulation. The results of the prothrombin time test are often expressed in terms of the International normalized ratio (INR), which is calculated as a ratio of the patient's prothrombin time (PT) to a control PT standardized for the potency of the thromboplastin reagent developed by the World Health Organization (WHO) using the formula: INR is equal to Patient PT divided by Control PT.\nsynonyms :Decreased INR; Decreased PT; Decreased international normalised ratio; Decreased international normalized ratio\n"}


{'id': 'HP_0032199', 'url': 'http://purl.obolibrary.org/obo/HP_0032199', 'lbl': 'Abnormal prothrombin time', 'desc': "label: Abnormal prothrombin time\ndefinition : Any deviation from the normal amount of time to coagulation in the prothrombin time test, which is a measure of the extrinsic pathway of coagulation. The results of the prothrombin time test are often expressed in terms of the International normalized ratio (INR), which is calculated as a ratio of the patient's prothrombin time (PT) to a control PT standardized for the potency of the thromboplastin reagent developed by the World Health Organization (WHO) using the formula: INR is equal to Patient PT divided by Control PT.\nsynonyms :Abnormal PT\n"}


{'id': 'HP_0032200', 'url': 'http://purl.obolibrary.org/obo/HP_0032200', 'lbl': 'Perivascular fibrosis', 'desc': 'label: Perivascular fibrosis\ndefinition : The presence of thick collagen bundles around blood vessels, often in an onion-skin type whorling pattern.\nsynonyms :\n'}


{'id': 'HP_0032201', 'url': 'http://purl.obolibrary.org/obo/HP_0032201', 'lbl': 'Rotator cuff tear', 'desc': 'label: Rotator cuff tear\ndefinition : The term rotator cuff describes the tendons connecting the infraspinatus, supraspinatus, teres minor, and subscapularis muscles to the humeral head.Traumatic tears of the rotator cuff tend to occur at the tendon-bone junction of the supraspinatus and greater tuberosity of the humerus whereas degenerative tears tend to be seen posteriorly at the junction of the supraspinatus and infraspinatu A rotator cuff tear is when one or more of these tendons tears or detaches from the humerus.\nsynonyms :\n'}


{'id': 'HP_0032202', 'url': 'http://purl.obolibrary.org/obo/HP_0032202', 'lbl': 'Vulvar intraepithelial neoplasia', 'desc': 'label: Vulvar intraepithelial neoplasia\ndefinition : Vulvar intraepithelial neoplasia (VIN) is widely accepted as the precursor lesion of vulvar squamous cell carcinoma (VSCC). VSCC arises via either a human papilloma virus (HPV)-associated pathway, or more commonly, via a mechanism independent of HPV, often being linked to chronic inflammatory conditions such as lichen sclerosus (LS). Accordingly, two distinct subtypes of VIN are recognised: the HPV-associated high-grade squamous intraepithelial lesion/usual VIN (HSIL/uVIN) and the non-HPV-associated differentiated VIN (dVIN). HSIL is clinically identified by its multifocal, warty appearance and on histology by conspicuous cytological and architectural atypia. Differentiated VIN, on the other hand, often produces ill-defined lesions, and on histology, notoriously mimics non-neoplastic epithelial disorders (NNED), particularly LS. As a result, dVIN is rarely identified in advance of a diagnosis of invasive malignancy, despite being the precursor lesion of the majority of VSCC.\nsynonyms :\n'}


{'id': 'HP_0032203', 'url': 'http://purl.obolibrary.org/obo/HP_0032203', 'lbl': 'Lymphoid nodular hyperplasia', 'desc': 'label: Lymphoid nodular hyperplasia\ndefinition : Lymphoid nodular hyperplasia (LNH) of the terminal ileum and colon has been considered a mucosal response to nonspecific stimuli, most often infections, and consequently has been regarded as a pathophysiologic phenomenon during infancy and childhood. LNH can be ascertained by colonoscopy, whereby a lymphoid nodule is defined as an extruding follicle with a diameter of not more than 2 mm, and LNH is defined as a cluster of not more than 10 of such extruding lymphoid nodules (see Figure 1 of PMID:17368236).\nsynonyms :Lymphonodular hyperplasia of the colon\n'}


{'id': 'HP_0032204', 'url': 'http://purl.obolibrary.org/obo/HP_0032204', 'lbl': 'Chronic active Epstein-Barr virus infection', 'desc': 'label: Chronic active Epstein-Barr virus infection\ndefinition : Chronic active Epstein-Barr virus (EBV) infection is an uncommon outcome of EBV infection and may present as a waxing and waning or fulminant syndrome. Unlike acute infectious mononucleosis, wherein EBV establishes lifelong infection and survives by maintaining a delicate balance with the host as a latent infection, in chronic active EBV infection the host-virus balance is disturbed.\nsynonyms :\n'}


{'id': 'HP_0032205', 'url': 'http://purl.obolibrary.org/obo/HP_0032205', 'lbl': 'Increased circulating galectin-3 level', 'desc': 'label: Increased circulating galectin-3 level\ndefinition : An increased circulation of galectin-3 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032207', 'url': 'http://purl.obolibrary.org/obo/HP_0032207', 'lbl': 'obsolete Abnormal cerebrospinal fluid metabolite concentration', 'desc': 'label: obsolete Abnormal cerebrospinal fluid metabolite concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032208', 'url': 'http://purl.obolibrary.org/obo/HP_0032208', 'lbl': 'Increased urinary type 1 collagen N-terminal telopeptide level', 'desc': 'label: Increased urinary type 1 collagen N-terminal telopeptide level\ndefinition : An increased concentration of type 1 collagen N-terminal telopeptide (NTx) level in the urine. Generally the test is performed over a period of time, for instance, 10 cc of morning urine can be collected following 12 hours overnight fasting or for 24 hours.\nsynonyms :Increased collagen crosslinked N-telopeptide [Moles/volume] in 24 hour urine; Increased urine NTx level\n'}


{'id': 'HP_0032209', 'url': 'http://purl.obolibrary.org/obo/HP_0032209', 'lbl': 'Abnormal circulating free T3 concentration', 'desc': 'label: Abnormal circulating free T3 concentration\ndefinition : A deviation from the normal concentration of free triiodothyronine (T3) in the blood circulation. A proportion of T3 is bound to plasma proteins in the blood, including mainly thyroxine binding globulin, transthyretin, and albumin. T3 that is not bound to a protein is referred to as free T3.\nsynonyms :Abnormal circulating free T3 level; Abnormal circulating free triiodotyronine concentration\n'}


{'id': 'HP_0032210', 'url': 'http://purl.obolibrary.org/obo/HP_0032210', 'lbl': 'Decreased circulating free T3', 'desc': "label: Decreased circulating free T3\ndefinition : A reduced concentration of free 3,3',5-triiodo-L-thyronine in the blood circulation.\nsynonyms :Decreased circulating free triiodothyronine\n"}


{'id': 'HP_0032211', 'url': 'http://purl.obolibrary.org/obo/HP_0032211', 'lbl': 'Increased urinary epithelial cell count', 'desc': 'label: Increased urinary epithelial cell count\ndefinition : An increased number of epithelial cells per high-power field in urinanalysis.\nsynonyms :\n'}


{'id': 'HP_0032212', 'url': 'http://purl.obolibrary.org/obo/HP_0032212', 'lbl': 'Increased urinary squamous epithelial cell count', 'desc': 'label: Increased urinary squamous epithelial cell count\ndefinition : An increased number of squamous epithelial cells per high-power field in urinanalysis.\nsynonyms :\n'}


{'id': 'HP_0032213', 'url': 'http://purl.obolibrary.org/obo/HP_0032213', 'lbl': 'Increased urinary renal tubular epithelial cell count', 'desc': 'label: Increased urinary renal tubular epithelial cell count\ndefinition : An increased number of renal tubular epithelial cells per high-power field in urinanalysis.\nsynonyms :\n'}


{'id': 'HP_0032214', 'url': 'http://purl.obolibrary.org/obo/HP_0032214', 'lbl': 'Increased urinary transitional epithelial cell count', 'desc': 'label: Increased urinary transitional epithelial cell count\ndefinition : An increased number of transitional epithelial cells per high-power field in urinanalysis.\nsynonyms :\n'}


{'id': 'HP_0032215', 'url': 'http://purl.obolibrary.org/obo/HP_0032215', 'lbl': 'Disseminated cutaneous warts', 'desc': 'label: Disseminated cutaneous warts\ndefinition : Multiple skin warts located in multiple parts of the body, e.g., neck, trunks, and extremities.\nsynonyms :\n'}


{'id': 'HP_0032216', 'url': 'http://purl.obolibrary.org/obo/HP_0032216', 'lbl': 'Lymphocytic infiltration of the colorectal mucosa', 'desc': 'label: Lymphocytic infiltration of the colorectal mucosa\ndefinition : Abnormally increased intraepithelial lymphocyte count. This finding may be appreciated as large numbers of surface intraepithelial lymphocytes as seen (for instance) with hematoxylin and eosin staining of a colonic biopsy sample taken during colonoscopy.\nsynonyms :\n'}


{'id': 'HP_0032217', 'url': 'http://purl.obolibrary.org/obo/HP_0032217', 'lbl': 'Indurated nodule', 'desc': 'label: Indurated nodule\ndefinition : A skin nodule that is unusually hard (indurated).\nsynonyms :\n'}


{'id': 'HP_0032218', 'url': 'http://purl.obolibrary.org/obo/HP_0032218', 'lbl': 'Decreased proportion of CD4-positive T cells', 'desc': 'label: Decreased proportion of CD4-positive T cells\ndefinition : A reduction in the proportion of CD4-positive T cells relative to the total number of T cells.\nsynonyms :Decreased proportion of CD4+ cells; Decreased proportion of CD4-positive, alpha-beta T cells; Reduced proportion of CD4-positive cells\n'}


{'id': 'HP_0032219', 'url': 'http://purl.obolibrary.org/obo/HP_0032219', 'lbl': 'Increased proportion of CD4-positive T cells', 'desc': 'label: Increased proportion of CD4-positive T cells\ndefinition : An elevation in the proportion of CD4-positive T cells relative to the total number of T cells.\nsynonyms :Elevated proportion of CD4-positive T cells; Increased proportion of CD4+ T cells; Increased proportion of CD4-positive, alpha-beta T cells\n'}


{'id': 'HP_0032220', 'url': 'http://purl.obolibrary.org/obo/HP_0032220', 'lbl': 'Interface hepatitis', 'desc': 'label: Interface hepatitis\ndefinition : Inflammation of the liver characterized by a mononuclear cell infiltrate whereby portal inflammatory cells extend through the limiting plate between the portal tract and liver parenchyma.\nsynonyms :\n'}


{'id': 'HP_0032221', 'url': 'http://purl.obolibrary.org/obo/HP_0032221', 'lbl': 'Periportal emperipolesis', 'desc': 'label: Periportal emperipolesis\ndefinition : The engulfing of lymphocytes by hepatocytes, which typically occurs in the interface hepatitis area.\nsynonyms :\n'}


{'id': 'HP_0032222', 'url': 'http://purl.obolibrary.org/obo/HP_0032222', 'lbl': 'Serrated intestinal polyps', 'desc': 'label: Serrated intestinal polyps\ndefinition : The presence of multiple serrated polyps in the intestine. Unlike conventional adenomas, which are uniformly dysplastic, the vast majority of serrated lesions contain no dysplasia. The serrated class includes the hyperplastic polyps, which are not considered precancerous; sessile serrated polyps (also called sessile serrated adenomas); and traditional serrated adenomas. Sessile serrated polyps are larger on average and more often located in the proximal colon. Sessile serrated polyps have a more irregular surface, a pattern to the surface that has been called cloudlike, and indistinct edges compared with hyperplastic polyps. Sessile serrated polyps also have large open pits on the surface (type O pits) when viewed with magnification.\nsynonyms :Serrated polyposis\n'}


{'id': 'HP_0032223', 'url': 'http://purl.obolibrary.org/obo/HP_0032223', 'lbl': 'Blood group', 'desc': 'label: Blood group\ndefinition : Any of the various types of human blood whose antigen characteristics determine compatibility in transfusion. While the ABO and Rhesus sytems are the most well known, there are in total about 300 different blood type antigens distributed across 34 different blood type systems.\nsynonyms :\n'}


{'id': 'HP_0032224', 'url': 'http://purl.obolibrary.org/obo/HP_0032224', 'lbl': 'ABO blood group', 'desc': 'label: ABO blood group\ndefinition : The ABO system consists of A and B antigens and antibodies against these antigens.\nsynonyms :\n'}


{'id': 'HP_0032225', 'url': 'http://purl.obolibrary.org/obo/HP_0032225', 'lbl': 'Perifollicular fibroma', 'desc': 'label: Perifollicular fibroma\ndefinition : Perifollicular fibroma is a rare cutaneous hamartoma that shows differentiation in the connective tissue sheath of hair follicles. It can occur as a solitary papule or as multiple lesions. Histologically, the lesion consists of a concentric arrangement of cellular fibrous tissue around a normal hair follicle.\nsynonyms :\n'}


{'id': 'HP_0032226', 'url': 'http://purl.obolibrary.org/obo/HP_0032226', 'lbl': 'Abnormal sebaceous gland morphology', 'desc': 'label: Abnormal sebaceous gland morphology\ndefinition : Any structural anomaly of the sebaceous glands.\nsynonyms :\n'}


{'id': 'HP_0032227', 'url': 'http://purl.obolibrary.org/obo/HP_0032227', 'lbl': 'Sebaceous hyperplasia', 'desc': 'label: Sebaceous hyperplasia\ndefinition : A common, benign skin condition involving hypertrophy of the sebaceous glands characterized by single or multiple lesions that manifest as yellow, soft, small papules with umbilication. The lesions are located commonly on the central face (specifically, the nose, cheeks and forehead) but may also occur elswehere, including the chest, mouth, scrotum, foreskin, penile shaft, vulva, and areola.\nsynonyms :\n'}


{'id': 'HP_0032228', 'url': 'http://purl.obolibrary.org/obo/HP_0032228', 'lbl': 'Trichodiscoma', 'desc': 'label: Trichodiscoma\ndefinition : A small benign fibrovascular tumor of the dermal part of the hair disk. Trichodiscoma is rather simple in appearance and consists of a dome-shaped fibrous tumor with a prominent vascular component that fills the papillary dermis under an atrophic epidermis. As in a normal hair disk, a hair follicle may be present at one edge of the papular lesion.\nsynonyms :\n'}


{'id': 'HP_0032229', 'url': 'http://purl.obolibrary.org/obo/HP_0032229', 'lbl': 'Perinuclear antineutrophil antibody positivity', 'desc': 'label: Perinuclear antineutrophil antibody positivity\ndefinition : The presence of autoantibodies in the serum that react against proteins predominantly expressed in perinuclear region of neutrophils.\nsynonyms :p-ANCA positivity\n'}


{'id': 'HP_0032230', 'url': 'http://purl.obolibrary.org/obo/HP_0032230', 'lbl': 'Cytoplasmic antineutrophil antibody positivity', 'desc': 'label: Cytoplasmic antineutrophil antibody positivity\ndefinition : The presence of autoantibodies in the serum that react against proteins predominantly expressed in cytoplasmic granules of neutrophils.\nsynonyms :Anti-neutrophil cytoplasmic antibody positivity\n'}


{'id': 'HP_0032231', 'url': 'http://purl.obolibrary.org/obo/HP_0032231', 'lbl': 'Hypochromia', 'desc': 'label: Hypochromia\ndefinition : A qualitative impression that red blood cells have less color than normal when examined under a microscope, usually related to a reduced amount of hemoglobin in the red blood cells.\nsynonyms :\n'}


{'id': 'HP_0032232', 'url': 'http://purl.obolibrary.org/obo/HP_0032232', 'lbl': 'Increased circulating creatine kinase MB isoform', 'desc': 'label: Increased circulating creatine kinase MB isoform\ndefinition : An increased concentration of the MB isoform of creatine kinase in the blood circulation.\nsynonyms :Increased circulating CK MB isoform\n'}


{'id': 'HP_0032233', 'url': 'http://purl.obolibrary.org/obo/HP_0032233', 'lbl': 'Increased circulating creatine kinase BB isoform', 'desc': 'label: Increased circulating creatine kinase BB isoform\ndefinition : An increased concentration of the BB isoform of creatine kinase in the blood circulation.\nsynonyms :Increased circulating CK BB isoform\n'}


{'id': 'HP_0032234', 'url': 'http://purl.obolibrary.org/obo/HP_0032234', 'lbl': 'Increased circulating creatine kinase MM isoform', 'desc': 'label: Increased circulating creatine kinase MM isoform\ndefinition : An increased concentration of the MM isoform of creatine kinase in the blood circulation.\nsynonyms :Increased circulating CK MM isoform\n'}


{'id': 'HP_0032235', 'url': 'http://purl.obolibrary.org/obo/HP_0032235', 'lbl': 'Anti-La/SS-B antibody positivity', 'desc': 'label: Anti-La/SS-B antibody positivity\ndefinition : The presence of autoantibodies in the blood circulation that react against La/SSB autoantigens.\nsynonyms :\n'}


{'id': 'HP_0032236', 'url': 'http://purl.obolibrary.org/obo/HP_0032236', 'lbl': 'Increased circulating immature neutrophil count', 'desc': 'label: Increased circulating immature neutrophil count\ndefinition : An abnormally increased number of immature neutrophils in the peripheral blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032237', 'url': 'http://purl.obolibrary.org/obo/HP_0032237', 'lbl': 'Increased circulating myelocyte count', 'desc': 'label: Increased circulating myelocyte count\ndefinition : An abnormally increased number of myelocytes in the peripheral blood circulation. Myelocytes are immature neutrophils with a size of 12-18 micrometers, a round or oval nucleus with no nucleoli, bluish-pink staining cytoplasm with primary and seconday granules, and a nucleus:cytoplasm ratio of 2:1.\nsynonyms :\n'}


{'id': 'HP_0032238', 'url': 'http://purl.obolibrary.org/obo/HP_0032238', 'lbl': 'Increased circulating metamyelocyte count', 'desc': 'label: Increased circulating metamyelocyte count\ndefinition : An abnormally increased number of metamyelocytes in the peripheral blood circulation. Metamyelocytes are immature neutrophils with a size of 10-18 micrometers, an indented or kidney-shaped nucleus, pinkish-blue staining cytoplasm with seconday granules, and a nucleus:cytoplasm ratio of 1.5:1.\nsynonyms :\n'}


{'id': 'HP_0032239', 'url': 'http://purl.obolibrary.org/obo/HP_0032239', 'lbl': 'Increased circulating band cell count', 'desc': 'label: Increased circulating band cell count\ndefinition : An abnormally increased number of band cells in the peripheral blood circulation. Band cells are immature neutrophils with a size of 10-18 micrometers, a horseshoe-shaped nucleus with no nucleoli, light-pink staining cytoplasm with many small seconday granules, and a nucleus:cytoplasm ratio of 1:2.\nsynonyms :Increased circulating band form neutrophils; Left shift\n'}


{'id': 'HP_0032240', 'url': 'http://purl.obolibrary.org/obo/HP_0032240', 'lbl': 'Elevated circulating E selectin level', 'desc': 'label: Elevated circulating E selectin level\ndefinition : An increased concentration of E selectin in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032241', 'url': 'http://purl.obolibrary.org/obo/HP_0032241', 'lbl': 'Cervical neoplasm', 'desc': 'label: Cervical neoplasm\ndefinition : A tumor (abnormal growth of tissue) of the uterine cervix.\nsynonyms :\n'}


{'id': 'HP_0032242', 'url': 'http://purl.obolibrary.org/obo/HP_0032242', 'lbl': 'Cervical intraepithelial neoplasia', 'desc': 'label: Cervical intraepithelial neoplasia\ndefinition : A precancerous condition characterized by dysplasia of the cervical epithelium. Cervical intraepithelial neoplasia (CIN) 1, 2 and 3 based on its relationship with the prognosis. CIN 1 is mild dysplasia, which is mostly observed because it disappears as part of its natural course. CIN 3 includes severe dysplasia and carcinoma in situ, and management involves treatment because it is highly likely to develop into invasive cancer.\nsynonyms :\n'}


{'id': 'HP_0032243', 'url': 'http://purl.obolibrary.org/obo/HP_0032243', 'lbl': 'Abnormal tissue metabolite concentration', 'desc': 'label: Abnormal tissue metabolite concentration\ndefinition : Any deviation from the normal concentration of a metabolite in a tissue.\nsynonyms :\n'}


{'id': 'HP_0032244', 'url': 'http://purl.obolibrary.org/obo/HP_0032244', 'lbl': 'Decreased serum thromboxane B2', 'desc': 'label: Decreased serum thromboxane B2\ndefinition : A reduction in the concentration of thromboxane B2 in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032245', 'url': 'http://purl.obolibrary.org/obo/HP_0032245', 'lbl': 'Abnormal metabolism', 'desc': 'label: Abnormal metabolism\ndefinition : An abnormality in the function of the chemical reactions related to processes including conversion of food to enter, synthesis of proteins, lipids, nucleic acids, and carbohydrates, or the elimination of waste products.\nsynonyms :\n'}


{'id': 'HP_0032247', 'url': 'http://purl.obolibrary.org/obo/HP_0032247', 'lbl': 'Persistent CMV viremia', 'desc': 'label: Persistent CMV viremia\ndefinition : Lasting (uncontrolled) presence of cytomegalovirus in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032248', 'url': 'http://purl.obolibrary.org/obo/HP_0032248', 'lbl': 'Persistent viremia', 'desc': 'label: Persistent viremia\ndefinition : Persistence of virus in the blood circulation longer than would be normal in an immunocompentent host.\nsynonyms :\n'}


{'id': 'HP_0032249', 'url': 'http://purl.obolibrary.org/obo/HP_0032249', 'lbl': 'Coccidioidomycosis', 'desc': 'label: Coccidioidomycosis\ndefinition : Infection by a Coccidioides species fungus. These are dimorphic, soil-dwelling, fungi known to cause a broad spectrum of disease, ranging from a mild febrile illness to severe pulmonary manifestations or disseminated disease. The genus Coccidioides is comprised of two genetically distinct species: Coccidioides immitis and C. posadasii.\nsynonyms :Valley fever\n'}


{'id': 'HP_0032250', 'url': 'http://purl.obolibrary.org/obo/HP_0032250', 'lbl': 'Acinetobacter infection', 'desc': 'label: Acinetobacter infection\ndefinition : An infection by Acinetobacter baumannii, a Gram-negative bacillus that is aerobic, pleomorphic and non-motile. An opportunistic pathogen, A. baumannii has a high incidence among immunocompromised individuals, particularly those who have experienced a prolonged (over 90 d) hospital stay.\nsynonyms :\n'}


{'id': 'HP_0032251', 'url': 'http://purl.obolibrary.org/obo/HP_0032251', 'lbl': 'Abnormal immune system morphology', 'desc': 'label: Abnormal immune system morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032252', 'url': 'http://purl.obolibrary.org/obo/HP_0032252', 'lbl': 'Granuloma', 'desc': 'label: Granuloma\ndefinition : A compact, organized collection of mature mononuclear phagocytes, which may be but is not necessarily accompanied by accessory features such as necrosis.\nsynonyms :\n'}


{'id': 'HP_0032253', 'url': 'http://purl.obolibrary.org/obo/HP_0032253', 'lbl': 'Eosinophilic granuloma', 'desc': 'label: Eosinophilic granuloma\ndefinition : A type of granuloma characterized morphologically by the predominance of Langerhans cells with characteristic grooved, folded, indented nuclei in the appropriate milieu that includes variable numbers of eosinophils and histiocytes including multinucleated forms, often appearing similar to osteoclasts or touton like giant cells, neutrophils and small lymphocytes. The concentration of the eosinophilic infiltrate varies from scattered mature cells to sheet-like masses of cells. Occasionally, areas of bone necrosis may interrupt the cellular infiltrate. The foamy cells may also be amassed in clumps, which are of no clinical significance because these clumps represent phagocytosis of lipid debris.\nsynonyms :\n'}


{'id': 'HP_0032254', 'url': 'http://purl.obolibrary.org/obo/HP_0032254', 'lbl': 'Increased circulating copper concentration', 'desc': 'label: Increased circulating copper concentration\ndefinition : An abnormally elevated concentration of copper in the blood circulation. This term refers to the total copper concentration.\nsynonyms :Elevated serum copper; Hypercupremia\n'}


{'id': 'HP_0032255', 'url': 'http://purl.obolibrary.org/obo/HP_0032255', 'lbl': 'Opportunistic fungal infection', 'desc': 'label: Opportunistic fungal infection\ndefinition : An infection that is caused by a fungus that would generally not be able to cause an infection in a host with a normal immune system. Such fungi take advantage of the opportunity, so to speak, that is provided by a weakened immune system.\nsynonyms :\n'}


{'id': 'HP_0032256', 'url': 'http://purl.obolibrary.org/obo/HP_0032256', 'lbl': 'Histoplasmosis', 'desc': 'label: Histoplasmosis\ndefinition : Histoplasmosis is caused by the fungus Histoplasma capsulatum and is consider to be an opportunistic infection in immunosuppressed persons.\nsynonyms :\n'}


{'id': 'HP_0032257', 'url': 'http://purl.obolibrary.org/obo/HP_0032257', 'lbl': 'Disseminated histoplasmosis', 'desc': 'label: Disseminated histoplasmosis\ndefinition : Histoplasmosis infection involving multiple sites of the body. Disseminated histoplasmosis can involve various organs, including reticuloendothelial organs, gastrointestinal tract, adrenal glands, central nervous system, endovascular structures, kidney, and skin. It typically presents with systemic symptoms like fever, generalized fatigue, night sweats, weight loss, and the symptoms related to the specific organ involved. Severe disseminated disease can manifest as septic shock, multi organ failure, and ARDS.\nsynonyms :\n'}


{'id': 'HP_0032258', 'url': 'http://purl.obolibrary.org/obo/HP_0032258', 'lbl': 'Pulmonary histoplasmosis', 'desc': 'label: Pulmonary histoplasmosis\ndefinition : Infection of the lungs with Histoplasma capsulatum. Symptoms may include fever, headache, weakness, chest pain and dry cough. When imaging is done, chest radiographs may show patchy pneumonia involving one or more lobes with adenopathy of the mediastinum or hilum.\nsynonyms :\n'}


{'id': 'HP_0032259', 'url': 'http://purl.obolibrary.org/obo/HP_0032259', 'lbl': 'Chronic tinea infection', 'desc': 'label: Chronic tinea infection\ndefinition : The term tinea means fungal infection, whereas dermatophyte refers to the fungal organisms that cause tinea. This term refers to a tinea infection that is chronic or recalcitrant to treatment and may be reflective of an immune defect.\nsynonyms :\n'}


{'id': 'HP_0032260', 'url': 'http://purl.obolibrary.org/obo/HP_0032260', 'lbl': 'Opportunistic bacterial infection', 'desc': 'label: Opportunistic bacterial infection\ndefinition : An infection that is caused by a bacterium that would generally not be able to cause an infection in a host with a normal immune system. Such bacteria take advantage of the opportunity, so to speak, that is provided by a weakened immune system.\nsynonyms :\n'}


{'id': 'HP_0032261', 'url': 'http://purl.obolibrary.org/obo/HP_0032261', 'lbl': 'Nontuberculous mycobacterial pulmonary infection', 'desc': 'label: Nontuberculous mycobacterial pulmonary infection\ndefinition : An infection of the lung caused by environmental mycobacteria. Such infections can occur in individuals with predisposing lung disease or immune disease.\nsynonyms :\n'}


{'id': 'HP_0032262', 'url': 'http://purl.obolibrary.org/obo/HP_0032262', 'lbl': 'Pulmonary tuberculosis', 'desc': 'label: Pulmonary tuberculosis\ndefinition : A lung infection by Mycobacterium tuberculosis a slightly curved non-motile, aerobic, non-capsulated and non-spore forming strains of mycobacteria.\nsynonyms :Pulmonary TB\n'}


{'id': 'HP_0032263', 'url': 'http://purl.obolibrary.org/obo/HP_0032263', 'lbl': 'Increased blood pressure', 'desc': 'label: Increased blood pressure\ndefinition : Abnormal increase in blood pressure. An individual measurement of increased blood pressure does not necessarily imply hypertension. In practical terms, multiple measurements are recommended to diagnose the presence of hypertension.\nsynonyms :Increased BP\n'}


{'id': 'HP_0032264', 'url': 'http://purl.obolibrary.org/obo/HP_0032264', 'lbl': 'Anti-NMDA receptor antibody positivity', 'desc': 'label: Anti-NMDA receptor antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against the NMDA (N-methyl-D-aspartate)-type glutamate receptor.\nsynonyms :Presence of anti-N-methyl-D-aspartate Receptor antibody in blood; Presence of anti-NMDAR antibody in blood\n'}


{'id': 'HP_0032265', 'url': 'http://purl.obolibrary.org/obo/HP_0032265', 'lbl': 'CSF autoimmune antibody positivity', 'desc': "label: CSF autoimmune antibody positivity\ndefinition : The presence of an antibody in the cerebrospinal fluid (CSF) that is directed against the organism's own cells or tissues.\nsynonyms :Cerebrospinal fluid autoimmune antibody positivity\n"}


{'id': 'HP_0032266', 'url': 'http://purl.obolibrary.org/obo/HP_0032266', 'lbl': 'CSF anti-NMDA receptor antibody positivity', 'desc': 'label: CSF anti-NMDA receptor antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the cerebrospinal fluid (CSF) that react against the NMDA (N-methyl-D-aspartate)-type glutamate receptor.\nsynonyms :Presence of NMDAR antibody in CSF; Presence of anti-N-methyl-D-aspartate Receptor antibody in CSF; Presence of anti-NMDAR antibody in cerebrospinal fluid\n'}


{'id': 'HP_0032267', 'url': 'http://purl.obolibrary.org/obo/HP_0032267', 'lbl': 'Empty delta sign', 'desc': 'label: Empty delta sign\ndefinition : This sign is created by a nonenhancing thrombus in the dural sinus surrounded by triangular enhancing dura as seen on cross-section. The sign, seen on contrast-enhanced CT scan images, suggests dural sinovenous thrombosis. It is best seen on wider window settings. It is a reliable sign of sinus thrombosis but is seen only in 25-30% of these cases.\nsynonyms :\n'}


{'id': 'HP_0032268', 'url': 'http://purl.obolibrary.org/obo/HP_0032268', 'lbl': 'Dural tail sign', 'desc': 'label: Dural tail sign\ndefinition : This sign represents thickening and enhancement of the dura mater in continuity with a mass, which on MR images, gives the appearance of a tail arising from the mass. The dural tail is thought to represent reactive change; however, it may also be due to tumor invasion. Three criteria need to be met for a positive dural tail sign: the tail should be seen on two successive images through the tumor, it should taper away from the tumor, and it must enhance more than the tumor.\nsynonyms :\n'}


{'id': 'HP_0032269', 'url': 'http://purl.obolibrary.org/obo/HP_0032269', 'lbl': 'Lemon sign', 'desc': 'label: Lemon sign\ndefinition : The lemon sign refers to the shape of the fetal skull at ultrasonography (US) when the frontal bones lose their normal convex contour and appear flattened or inwardly scalloped. This gives the skull a shape that is said to resemble a lemon.. The sign is seen on transverse sonograms of the fetal cranium obtained at the level of the ventricles.\nsynonyms :\n'}


{'id': 'HP_0032270', 'url': 'http://purl.obolibrary.org/obo/HP_0032270', 'lbl': 'Optic nerve tram-track sign', 'desc': 'label: Optic nerve tram-track sign\ndefinition : A tram-track sign is composed of two enhancing areas of tumor separated from each other by the negative defect of the optic nerve. It is seen on contrast-enhanced CT scan and MRI images, in optic nerve sheath meningioma. The sign helps distinguish between optic nerve sheath meningioma and optic glioma. Optic glioma arises from glial cells within the optic nerve and there is no clear separation between the nerve and the tumor; hence the tram-track sign is not seen in optic gliomas. Calcification may be seen in optic nerve sheath meningiomas in 20-50% of cases and hence the tram-track sign may be seen on nonenhanced CT scan images as a linear calcification around the nerve, but this is less common.\nsynonyms :\n'}


{'id': 'HP_0032271', 'url': 'http://purl.obolibrary.org/obo/HP_0032271', 'lbl': 'Extrapulmonary tuberculosis', 'desc': 'label: Extrapulmonary tuberculosis\ndefinition : A type of tubercular infection located outside of the lung, which is the most common location of tuberculosis. There are two types of clinical manifestation of tuberculosis (TB) are pulmonary TB (PTB) and extrapulmonary TB (EPTB). The former is most common. EPTB refers to TB involving organs other than the lungs (e.g., pleura, lymph nodes, abdomen, genitourinary tract, skin, joints and bones, or meninges). A patient with both pulmonary and EPTB is classified as a case of PTB.\nsynonyms :Extrapulmonary TB\n'}


{'id': 'HP_0032272', 'url': 'http://purl.obolibrary.org/obo/HP_0032272', 'lbl': 'Elevated urinary N-acetylaspartic acid level', 'desc': 'label: Elevated urinary N-acetylaspartic acid level\ndefinition : Elevated N-acetylaspartic acid (NAA) in urine. This feature can be measured using gas chromatography-mass spectrometry.\nsynonyms :\n'}


{'id': 'HP_0032273', 'url': 'http://purl.obolibrary.org/obo/HP_0032273', 'lbl': 'Increased circulating N-acetylaspartic acid concentration', 'desc': 'label: Increased circulating N-acetylaspartic acid concentration\ndefinition : Concentration of N-acetylaspartic acid in the blood circulation above the upper limit of normal.\nsynonyms :Increased circulating N-acetyl aspartate level; Increased circulating N-acetyl aspartic acid level; Increased circulating N-acetyl-L-aspartic acid level; Increased circulating N-acetylaspartate level; Increased circulating NAA level\n'}


{'id': 'HP_0032274', 'url': 'http://purl.obolibrary.org/obo/HP_0032274', 'lbl': 'Increased CSF N-acetylaspartic acid concentration', 'desc': 'label: Increased CSF N-acetylaspartic acid concentration\ndefinition : An abnormally increased concentration of N-acetylaspartic acid in the cerebrospinal fluid (CSF).\nsynonyms :Increased N-acetyl aspartate levels in CSF; Increased N-acetyl aspartic acid levels in CSF; Increased N-acetyl-L-aspartic acid levels in CSF; Increased N-acetylaspartate levels in CSF; Increased NAA levels in CSF\n'}


{'id': 'HP_0032275', 'url': 'http://purl.obolibrary.org/obo/HP_0032275', 'lbl': 'Recurrent shingles', 'desc': 'label: Recurrent shingles\ndefinition : Repeated episodes of a localized, painful cutaneous eruption related to reactivation of varicella zoster virus (VZV) and characterized by a characteristic rash in one or two adjacent dermatomes.\nsynonyms :\n'}


{'id': 'HP_0032276', 'url': 'http://purl.obolibrary.org/obo/HP_0032276', 'lbl': 'Prominent subcalcaneal fat pad', 'desc': 'label: Prominent subcalcaneal fat pad\ndefinition : Abnormally increased prominence of the fat pad underneath the heal. This feature can be appreciated in figure 1 of PMID:26769062.\nsynonyms :\n'}


{'id': 'HP_0032277', 'url': 'http://purl.obolibrary.org/obo/HP_0032277', 'lbl': 'Lozenge-shaped umbilicus', 'desc': 'label: Lozenge-shaped umbilicus\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032278', 'url': 'http://purl.obolibrary.org/obo/HP_0032278', 'lbl': '2-hydroxyglutarate aciduria', 'desc': 'label: 2-hydroxyglutarate aciduria\ndefinition : An increase in the level of 2-hydroxyglutaric acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0032281', 'url': 'http://purl.obolibrary.org/obo/HP_0032281', 'lbl': 'Abnormal base excess', 'desc': 'label: Abnormal base excess\ndefinition : Deviation from the normal quantity of base excess, defined as the amount of strong acid (in millimoles per liter) that needs to be added in vitro to 1 liter of fully oxygenated whole blood to return a blood sample to standard conditions (pH of 7.40, Pco2 of 40 mm Hg, and temperature of 37 degrees C).\nsynonyms :\n'}


{'id': 'HP_0032282', 'url': 'http://purl.obolibrary.org/obo/HP_0032282', 'lbl': 'Contact dermatitis', 'desc': 'label: Contact dermatitis\ndefinition : An inflammatory process in skin caused by an exogenous agent that directly or indirectly injure the skin. If the offending agent is identified and removed, the eruption will resolve. An unusual or patterned eruption may be a clue to the presence of a contact dermatitis. Patch testing may be helpful in the differential diagnosis.\nsynonyms :\n'}


{'id': 'HP_0032283', 'url': 'http://purl.obolibrary.org/obo/HP_0032283', 'lbl': 'Disseminated nontuberculous mycobacterial infection', 'desc': 'label: Disseminated nontuberculous mycobacterial infection\ndefinition : An infection with nontuberculous mycobacteria that affects multiple body sites. Such infections can occur in individuals with immune disease.\nsynonyms :\n'}


{'id': 'HP_0032284', 'url': 'http://purl.obolibrary.org/obo/HP_0032284', 'lbl': 'Ultra-low vision with retained motion projection', 'desc': 'label: Ultra-low vision with retained motion projection\ndefinition : Ultra-low vision but with retained ability to identify a moving object (typically hand motion at distance of 30 cm).\nsynonyms :\n'}


{'id': 'HP_0032285', 'url': 'http://purl.obolibrary.org/obo/HP_0032285', 'lbl': 'Ultra-low vision with retained light projection', 'desc': 'label: Ultra-low vision with retained light projection\ndefinition : Ultra-low vision but with retained ability to perceive the difference between light and dark. Also when light is projected in each of the four quadrants of the visual field, the individual is able to correctly identify the origin of the light stimulus.\nsynonyms :\n'}


{'id': 'HP_0032286', 'url': 'http://purl.obolibrary.org/obo/HP_0032286', 'lbl': 'Ultra-low vision with retained light perception', 'desc': 'label: Ultra-low vision with retained light perception\ndefinition : Ultra-low vision but with retained ability to perceive the difference between light and dark.\nsynonyms :\n'}


{'id': 'HP_0032287', 'url': 'http://purl.obolibrary.org/obo/HP_0032287', 'lbl': 'Ultra-low vision with no light perception', 'desc': 'label: Ultra-low vision with no light perception\ndefinition : Ultra-low vision with complete lack of light and form perception.\nsynonyms :\n'}


{'id': 'HP_0032288', 'url': 'http://purl.obolibrary.org/obo/HP_0032288', 'lbl': 'Polyclonal elevation of circulating IgG', 'desc': 'label: Polyclonal elevation of circulating IgG\ndefinition : An increase in polyclonal immunoglobulins resulting from many different plasma cells. On serum electrophoresis, a polyclonal gammopathy is characterized by a broad diffuse band with one or more heavy chains and kappa and lambda light chains.\nsynonyms :\n'}


{'id': 'HP_0032289', 'url': 'http://purl.obolibrary.org/obo/HP_0032289', 'lbl': 'Oligoclonal elevation of circulating IgG', 'desc': 'label: Oligoclonal elevation of circulating IgG\ndefinition : An increase in circulating immunoglobulins characterized by two or more bands in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032290', 'url': 'http://purl.obolibrary.org/obo/HP_0032290', 'lbl': 'Monoclonal elevation of IgG', 'desc': 'label: Monoclonal elevation of IgG\ndefinition : An increase in circulating immunoglobulins characterized by a single band in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032291', 'url': 'http://purl.obolibrary.org/obo/HP_0032291', 'lbl': 'Monoclonal elevation of intact IgG', 'desc': 'label: Monoclonal elevation of intact IgG\ndefinition : A type of monoclonal elevation of IgG in which the involved immunoglobulin has a normal structure with a light and heavy chain.\nsynonyms :\n'}


{'id': 'HP_0032292', 'url': 'http://purl.obolibrary.org/obo/HP_0032292', 'lbl': 'Monoclonal elevation of IgG light chain', 'desc': 'label: Monoclonal elevation of IgG light chain\ndefinition : A type of monoclonal elevation of IgG in which the involved immunoglobulin has an abnormal structure with a light chain but not a heavy chain.\nsynonyms :\n'}


{'id': 'HP_0032293', 'url': 'http://purl.obolibrary.org/obo/HP_0032293', 'lbl': 'Monoclonal elevation of IgG heavy chain', 'desc': 'label: Monoclonal elevation of IgG heavy chain\ndefinition : A type of monoclonal elevation of IgG in which the involved immunoglobulin has an abnormal structure with a heavy chain but not a light chain.\nsynonyms :\n'}


{'id': 'HP_0032294', 'url': 'http://purl.obolibrary.org/obo/HP_0032294', 'lbl': 'Monoclonal elevation of IgG kappa chain', 'desc': 'label: Monoclonal elevation of IgG kappa chain\ndefinition : A type of monoclonal elevation of IgG in which the involved immunoglobulin has an abnormal structure with a kappa light chain but not a heavy chain.\nsynonyms :\n'}


{'id': 'HP_0032295', 'url': 'http://purl.obolibrary.org/obo/HP_0032295', 'lbl': 'Monoclonal elevation of IgG lambda chain', 'desc': 'label: Monoclonal elevation of IgG lambda chain\ndefinition : A type of monoclonal elevation of IgG in which the involved immunoglobulin has an abnormal structure with a lambda light chain but not a heavy chain.\nsynonyms :\n'}


{'id': 'HP_0032296', 'url': 'http://purl.obolibrary.org/obo/HP_0032296', 'lbl': 'Increased circulating IgG subclass', 'desc': 'label: Increased circulating IgG subclass\ndefinition : An elevation of circulating IgG level predominantly related to an elevation of one of the four IgG subclasses.\nsynonyms :\n'}


{'id': 'HP_0032297', 'url': 'http://purl.obolibrary.org/obo/HP_0032297', 'lbl': 'Increased circulating IgG3 level', 'desc': 'label: Increased circulating IgG3 level\ndefinition : An abnormally increased concentration of the IgG3 subtype in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032298', 'url': 'http://purl.obolibrary.org/obo/HP_0032298', 'lbl': 'Increased circulating IgG1 level', 'desc': 'label: Increased circulating IgG1 level\ndefinition : An abnormally increased concentration of the IgG1 subtype in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032299', 'url': 'http://purl.obolibrary.org/obo/HP_0032299', 'lbl': 'Increased circulating IgG2 level', 'desc': 'label: Increased circulating IgG2 level\ndefinition : An abnormally increased concentration of the IgG2 subtype in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032300', 'url': 'http://purl.obolibrary.org/obo/HP_0032300', 'lbl': 'Increased circulating IgG4 level', 'desc': 'label: Increased circulating IgG4 level\ndefinition : An abnormally increased concentration of the IgG4 subtype in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032301', 'url': 'http://purl.obolibrary.org/obo/HP_0032301', 'lbl': 'Genital warts', 'desc': 'label: Genital warts\ndefinition : Warts affecting the skin in the genital area (peniile shaft, scrotum, vagina, or labia majora). Warts can be small, beginning as a pinhead-size swelling that may become larger and take on a pdenuculated appearance. Warts can spread and coalesce into large masses in the genital or anal area. Their color is variable but tends to be skin colored or darker, and they may occasionally bleed. Warts may cause itching, redness, or discomfort. An outbreak of genital warts may also cause psychological distress.\nsynonyms :\n'}


{'id': 'HP_0032302', 'url': 'http://purl.obolibrary.org/obo/HP_0032302', 'lbl': 'Kappa Bence Jones proteinuria', 'desc': 'label: Kappa Bence Jones proteinuria\ndefinition : The presence of free monoclonal kappa immunoglobulin light chains in the urine.\nsynonyms :\n'}


{'id': 'HP_0032303', 'url': 'http://purl.obolibrary.org/obo/HP_0032303', 'lbl': 'Lambda Bence Jones proteinuria', 'desc': 'label: Lambda Bence Jones proteinuria\ndefinition : The presence of free monoclonal lambda immunoglobulin light chains in the urine.\nsynonyms :\n'}


{'id': 'HP_0032304', 'url': 'http://purl.obolibrary.org/obo/HP_0032304', 'lbl': 'Abnormal circulating mannose-binding protein concentration', 'desc': 'label: Abnormal circulating mannose-binding protein concentration\ndefinition : Any deviation from the normal concentration of mannose-binding protein in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032305', 'url': 'http://purl.obolibrary.org/obo/HP_0032305', 'lbl': 'Decreased circulating mannose-binding protein concentration', 'desc': 'label: Decreased circulating mannose-binding protein concentration\ndefinition : Concentration of mannose-binding protein in the blood circulation below the lower limit of normal.\nsynonyms :Decreased mannose-binding protein level\n'}


{'id': 'HP_0032306', 'url': 'http://purl.obolibrary.org/obo/HP_0032306', 'lbl': 'Increased circulating mannose-binding protein concentration', 'desc': 'label: Increased circulating mannose-binding protein concentration\ndefinition : Concentration of mannose-binding protein in the blood circulation above the upper limit of normal.\nsynonyms :Increased mannose-binding protein level\n'}


{'id': 'HP_0032308', 'url': 'http://purl.obolibrary.org/obo/HP_0032308', 'lbl': 'Increased circulating procalcitonin concentration', 'desc': 'label: Increased circulating procalcitonin concentration\ndefinition : An elevated concentration of procalcitonin in the blood circulation.\nsynonyms :Increased circulating procalcitonin level\n'}


{'id': 'HP_0032309', 'url': 'http://purl.obolibrary.org/obo/HP_0032309', 'lbl': 'Abnormal granulocyte count', 'desc': 'label: Abnormal granulocyte count\ndefinition : Any deviation from the normal cell count per volume of granulocytes in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032310', 'url': 'http://purl.obolibrary.org/obo/HP_0032310', 'lbl': 'Granulocytosis', 'desc': 'label: Granulocytosis\ndefinition : An increased count of granulocytes in the peripheral blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032311', 'url': 'http://purl.obolibrary.org/obo/HP_0032311', 'lbl': 'Increased circulating globulin level', 'desc': 'label: Increased circulating globulin level\ndefinition : An abnormally elevated concentration of globulins in the blood.\nsynonyms :\n'}


{'id': 'HP_0032312', 'url': 'http://purl.obolibrary.org/obo/HP_0032312', 'lbl': 'Decreased circulating globulin level', 'desc': 'label: Decreased circulating globulin level\ndefinition : An abnormally reduced concentration of globulins in the blood.\nsynonyms :\n'}


{'id': 'HP_0032313', 'url': 'http://purl.obolibrary.org/obo/HP_0032313', 'lbl': 'Frontotemporal hypertrichosis', 'desc': 'label: Frontotemporal hypertrichosis\ndefinition : Excessive, increased hair growth located in the region of the forehead and temple.\nsynonyms :\n'}


{'id': 'HP_0032314', 'url': 'http://purl.obolibrary.org/obo/HP_0032314', 'lbl': 'Abnormal areolar morphology', 'desc': 'label: Abnormal areolar morphology\ndefinition : An abnormal appearance or structure of the ring of pigmented skin that surrounds the nipple.\nsynonyms :\n'}


{'id': 'HP_0032315', 'url': 'http://purl.obolibrary.org/obo/HP_0032315', 'lbl': 'Areolar fullness', 'desc': 'label: Areolar fullness\ndefinition : The areola (ring of pigmented skin surrounding the nipple) is filled out so as to produce a rounded shape.\nsynonyms :\n'}


{'id': 'HP_0032316', 'url': 'http://purl.obolibrary.org/obo/HP_0032316', 'lbl': 'Family history', 'desc': 'label: Family history\ndefinition : Information about close relatives of an individual who is the proband of a study or who is being investigated with the goal of identifying a medical diagnosis. Usually, the family history includes information from three generations of relatives, including children, brothers and sisters, parents, aunts and uncles, nieces and nephews, grandparents, and cousins.\nsynonyms :\n'}


{'id': 'HP_0032317', 'url': 'http://purl.obolibrary.org/obo/HP_0032317', 'lbl': 'Family history of cancer', 'desc': 'label: Family history of cancer\ndefinition : A close blood relative had cancer.\nsynonyms :\n'}


{'id': 'HP_0032318', 'url': 'http://purl.obolibrary.org/obo/HP_0032318', 'lbl': 'Family history of heart disease', 'desc': 'label: Family history of heart disease\ndefinition : A close blood relative had heart disease.\nsynonyms :\n'}


{'id': 'HP_0032319', 'url': 'http://purl.obolibrary.org/obo/HP_0032319', 'lbl': 'Health status', 'desc': 'label: Health status\ndefinition : Health status of a family member with respect to the disease being investigated in a proband.\nsynonyms :\n'}


{'id': 'HP_0032320', 'url': 'http://purl.obolibrary.org/obo/HP_0032320', 'lbl': 'Affected', 'desc': 'label: Affected\ndefinition : This term applies to a family member who is diagnosed with the same condition as the individual who is the primary focus of investigation (the proband).\nsynonyms :\n'}


{'id': 'HP_0032321', 'url': 'http://purl.obolibrary.org/obo/HP_0032321', 'lbl': 'Unaffected', 'desc': 'label: Unaffected\ndefinition : This term applies to a family member in whom the diagnosis that is the primary focus of investigation is excluded.\nsynonyms :\n'}


{'id': 'HP_0032322', 'url': 'http://purl.obolibrary.org/obo/HP_0032322', 'lbl': 'Healthy', 'desc': 'label: Healthy\ndefinition : No history of any serious disease, including the disease being investigated in the proband.\nsynonyms :\n'}


{'id': 'HP_0032323', 'url': 'http://purl.obolibrary.org/obo/HP_0032323', 'lbl': 'Periodic fever', 'desc': 'label: Periodic fever\ndefinition : Episodic fever that recurs at regular intervals.\nsynonyms :\n'}


{'id': 'HP_0032324', 'url': 'http://purl.obolibrary.org/obo/HP_0032324', 'lbl': 'Non-periodic recurrent fever', 'desc': 'label: Non-periodic recurrent fever\ndefinition : Episodic fever that recurs at irregular intervals.\nsynonyms :\n'}


{'id': 'HP_0032325', 'url': 'http://purl.obolibrary.org/obo/HP_0032325', 'lbl': 'Lacunar stroke', 'desc': 'label: Lacunar stroke\ndefinition : A stroke related to a small infarct (2-20 mm in diameter) in the deep cerebral white matter, basal ganglia, or pons, that is presumed to result from the occlusion of a single small perforating artery supplying the subcortical areas of the brain.\nsynonyms :\n'}


{'id': 'HP_0032326', 'url': 'http://purl.obolibrary.org/obo/HP_0032326', 'lbl': 'Methicillin-resistant Staphylococcus aureus infection', 'desc': 'label: Methicillin-resistant Staphylococcus aureus infection\ndefinition : Infection with staphylococcus aureus resistant to the antibiotic methicillin (MRSA). MRSA can infect any individual but is more common among hospitalized patients, and can also occur as an opportunistic infection.\nsynonyms :MRSA infection\n'}


{'id': 'HP_0032327', 'url': 'http://purl.obolibrary.org/obo/HP_0032327', 'lbl': 'Interhemispheric cyst', 'desc': 'label: Interhemispheric cyst\ndefinition : Cystic collection (sac-like, fluid containing pocket of membranous tissue) located in the interhemispheric fissure, with or without communication with the ventricular system.\nsynonyms :\n'}


{'id': 'HP_0032328', 'url': 'http://purl.obolibrary.org/obo/HP_0032328', 'lbl': 'Temporomandibular joint adhesion', 'desc': 'label: Temporomandibular joint adhesion\ndefinition : Formation of one or more fibrous bands within the temporomandibular joint (TMJ) with resulting limitation of movement of the TMJ. Adhesions may be seen in degenerative processes that involve the TMJ.\nsynonyms :\n'}


{'id': 'HP_0032329', 'url': 'http://purl.obolibrary.org/obo/HP_0032329', 'lbl': 'Increased urinary 11-deoxycortisol level', 'desc': 'label: Increased urinary 11-deoxycortisol level\ndefinition : An abnormally elevated concentration of 11-deoxycortisol in the urine.\nsynonyms :\n'}


{'id': 'HP_0032330', 'url': 'http://purl.obolibrary.org/obo/HP_0032330', 'lbl': 'Increased urinary 11-deoxycorticosterone level', 'desc': 'label: Increased urinary 11-deoxycorticosterone level\ndefinition : An abnormally elevated concentration or amount of 11-deoxycorticosterone in the urine.\nsynonyms :\n'}


{'id': 'HP_0032331', 'url': 'http://purl.obolibrary.org/obo/HP_0032331', 'lbl': 'Increased urinary 11-deoxytetrahydrocorticosterone level', 'desc': 'label: Increased urinary 11-deoxytetrahydrocorticosterone level\ndefinition : An abnormally elevated concentration or amount of 11-deoxytetrahydrocorticosterone the urine.\nsynonyms :\n'}


{'id': 'HP_0032332', 'url': 'http://purl.obolibrary.org/obo/HP_0032332', 'lbl': 'Oligoclonal elevation of circulating IgM', 'desc': 'label: Oligoclonal elevation of circulating IgM\ndefinition : An increase in circulating IgM characterized by two or more bands in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase.\nsynonyms :\n'}


{'id': 'HP_0032333', 'url': 'http://purl.obolibrary.org/obo/HP_0032333', 'lbl': 'Polyclonal elevation of circulating IgA', 'desc': 'label: Polyclonal elevation of circulating IgA\ndefinition : A heterogeneous increase in IgA mmunoglobulins characterized by a diffuse band on serum electrophoresis.\nsynonyms :\n'}


{'id': 'HP_0032334', 'url': 'http://purl.obolibrary.org/obo/HP_0032334', 'lbl': 'Oligoclonal elevation of circulating IgA', 'desc': 'label: Oligoclonal elevation of circulating IgA\ndefinition : An increase in circulating IgA characterized by two or more bands in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032335', 'url': 'http://purl.obolibrary.org/obo/HP_0032335', 'lbl': 'Monoclonal elevation of circulating IgA', 'desc': 'label: Monoclonal elevation of circulating IgA\ndefinition : An increase in circulating IgA characterized by one predominant band in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032336', 'url': 'http://purl.obolibrary.org/obo/HP_0032336', 'lbl': 'Increased circulating specific IgE antibody', 'desc': 'label: Increased circulating specific IgE antibody\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032337', 'url': 'http://purl.obolibrary.org/obo/HP_0032337', 'lbl': 'Monoclonal elevation of circulating IgE', 'desc': 'label: Monoclonal elevation of circulating IgE\ndefinition : An increase in circulating IgE characterized by one predominant band in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032338', 'url': 'http://purl.obolibrary.org/obo/HP_0032338', 'lbl': 'Oligoclonal elevation of circulating IgE', 'desc': 'label: Oligoclonal elevation of circulating IgE\ndefinition : An increase in circulating IgE characterized by two or more bands in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0032339', 'url': 'http://purl.obolibrary.org/obo/HP_0032339', 'lbl': 'Polyclonal elevation of circulating IgE', 'desc': 'label: Polyclonal elevation of circulating IgE\ndefinition : A heterogeneous increase in IgE mmunoglobulins characterized by a diffuse band on serum electrophoresis.\nsynonyms :\n'}


{'id': 'HP_0032340', 'url': 'http://purl.obolibrary.org/obo/HP_0032340', 'lbl': 'obsolete Abnormal spirometry test', 'desc': 'label: obsolete Abnormal spirometry test\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032341', 'url': 'http://purl.obolibrary.org/obo/HP_0032341', 'lbl': 'Reduced forced vital capacity', 'desc': 'label: Reduced forced vital capacity\ndefinition : An abnormal reduction in the amount of air a person can expel following maximal inspiration.\nsynonyms :Decreased forced vital capacity; Reduced FVC\n'}


{'id': 'HP_0032342', 'url': 'http://purl.obolibrary.org/obo/HP_0032342', 'lbl': 'Reduced forced expiratory volume in one second', 'desc': 'label: Reduced forced expiratory volume in one second\ndefinition : An abnormal reduction in the amount of air a person can forcefully expel in one second.\nsynonyms :Reduced FEV1\n'}


{'id': 'HP_0032344', 'url': 'http://purl.obolibrary.org/obo/HP_0032344', 'lbl': 'Upslanting toenail', 'desc': 'label: Upslanting toenail\ndefinition : Upturned concavity of toenails.\nsynonyms :Ski-jump toenail; Upturned toenail\n'}


{'id': 'HP_0032345', 'url': 'http://purl.obolibrary.org/obo/HP_0032345', 'lbl': 'Elevated cancer Ag 19-9 level', 'desc': 'label: Elevated cancer Ag 19-9 level\ndefinition : An abnormal increased in the amount of the carbohydrate antigen 19-9, a recognizable sialo-ganglioside in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0032346', 'url': 'http://purl.obolibrary.org/obo/HP_0032346', 'lbl': 'Cutaneous lichen amyloidosis', 'desc': 'label: Cutaneous lichen amyloidosis\ndefinition : Lichen amyloidosis presents with multiple localized or rarely generalized, hyperpigmented grouped papules with a predilection for the shins, calves, ankles, and dorsa of the feet and thighs.\nsynonyms :\n'}


{'id': 'HP_0032347', 'url': 'http://purl.obolibrary.org/obo/HP_0032347', 'lbl': 'Cutaneous macular amyloidosis', 'desc': 'label: Cutaneous macular amyloidosis\ndefinition : A type of cutaneous amyloidosis that is characterized by hyperpigmented patches with indefinite margins composed of grayish brown macules, often with a reticulated or rippled appearance.\nsynonyms :Macular amyloidosis\n'}


{'id': 'HP_0032348', 'url': 'http://purl.obolibrary.org/obo/HP_0032348', 'lbl': 'Cutaneous nodular amyloidosis', 'desc': 'label: Cutaneous nodular amyloidosis\ndefinition : A type of cutaneous amyloidosis that is characterized clinically by waxy, purpuric plaques and nodules and histologically by amyloid deposits in the dermis and subcutaneous tissue.\nsynonyms :\n'}


{'id': 'HP_0032349', 'url': 'http://purl.obolibrary.org/obo/HP_0032349', 'lbl': 'Serinuria', 'desc': 'label: Serinuria\ndefinition : A increased concentration of serine in the urine.\nsynonyms :\n'}


{'id': 'HP_0032350', 'url': 'http://purl.obolibrary.org/obo/HP_0032350', 'lbl': 'Sulfocysteinuria', 'desc': 'label: Sulfocysteinuria\ndefinition : A increased concentration of sulfocysteine in the urine.\nsynonyms :\n'}


{'id': 'HP_0032351', 'url': 'http://purl.obolibrary.org/obo/HP_0032351', 'lbl': 'Phenylalaninuria', 'desc': 'label: Phenylalaninuria\ndefinition : Increased level of phenylalanine in urine.\nsynonyms :Increased level of phenylalanine in urine\n'}


{'id': 'HP_0032352', 'url': 'http://purl.obolibrary.org/obo/HP_0032352', 'lbl': 'Methioninuria', 'desc': 'label: Methioninuria\ndefinition : Level of methionine in urine above the upper limit of normal.\nsynonyms :Methionine high in urine\n'}


{'id': 'HP_0032353', 'url': 'http://purl.obolibrary.org/obo/HP_0032353', 'lbl': 'Leucinuria', 'desc': 'label: Leucinuria\ndefinition : Increased level of leucine in urine.\nsynonyms :\n'}


{'id': 'HP_0032355', 'url': 'http://purl.obolibrary.org/obo/HP_0032355', 'lbl': 'Decreased peak expiratory flow', 'desc': 'label: Decreased peak expiratory flow\ndefinition : A reduction in the maximum expiratory flow per minute, which can be used to measure how fast a subject can exhale as well as to judge the strength of the expiratory muscles and the condition of the large airways.\nsynonyms :\n'}


{'id': 'HP_0032356', 'url': 'http://purl.obolibrary.org/obo/HP_0032356', 'lbl': 'Decreased pre-bronchodilator forced vital capacity', 'desc': 'label: Decreased pre-bronchodilator forced vital capacity\ndefinition : An abnormal reduction in the amount of air a person can expel following maximal insipiration, with the test being performed before the administration of a bronchodilating medication.\nsynonyms :Decreased pre bronchodilator forced vital capacity; Decreased prebronchodilator forced vital capacity\n'}


{'id': 'HP_0032357', 'url': 'http://purl.obolibrary.org/obo/HP_0032357', 'lbl': 'Decreased post-bronchodilator forced vital capacity', 'desc': 'label: Decreased post-bronchodilator forced vital capacity\ndefinition : An abnormal reduction in the amount of air a person can expel following maximal insipiration, with the test being performed after the administration of a bronchodilating medication.\nsynonyms :Decreased post bronchodilator forced vital capacity; Decreased postbronchodilator forced vital capacity\n'}


{'id': 'HP_0032358', 'url': 'http://purl.obolibrary.org/obo/HP_0032358', 'lbl': 'Decreased post-bronchodilator forced expiratory volume in one second', 'desc': 'label: Decreased post-bronchodilator forced expiratory volume in one second\ndefinition : An abnormal reduction in the amount of air a person can forcefully expel in one second, with the test being performed after the administration of a bronchodilating medication.\nsynonyms :Decreased post bronchodilator forced expiratory volume in one second; Decreased postbronchodilator forced expiratory volume in one second\n'}


{'id': 'HP_0032359', 'url': 'http://purl.obolibrary.org/obo/HP_0032359', 'lbl': 'Decreased forced expiratory flow 25-75%', 'desc': 'label: Decreased forced expiratory flow 25-75%\ndefinition : A reduction compared to the predicted value of the forced expiratory flow over the middle one-half of the FVC; the average flow from the point at which 25% of the FVC has been exhaled to the point at which 75% of the FVC has been exhaled.\nsynonyms :Decreased FEF25-75%\n'}


{'id': 'HP_0032360', 'url': 'http://purl.obolibrary.org/obo/HP_0032360', 'lbl': 'Decreased pre-bronchodilator forced expiratory flow 25-75%', 'desc': 'label: Decreased pre-bronchodilator forced expiratory flow 25-75%\ndefinition : A reduction compared to the predicted value of the forced expiratory flow over the middle one-half of the FVC; the average flow from the point at which 25% of the FVC has been exhaled to the point at which 75% of the FVC has been exhaled. Here, the test is performed before the administration of a bronchodilating medication.\nsynonyms :Decreased pre bronchodilator forced expiratory flow 25-75%; Decreased pre-bronchodilator FEF25-75%; Decreased prebronchodilator forced expiratory flow 25-75%\n'}


{'id': 'HP_0032361', 'url': 'http://purl.obolibrary.org/obo/HP_0032361', 'lbl': 'Decreased post-bronchodilator forced expiratory flow 25-75%', 'desc': 'label: Decreased post-bronchodilator forced expiratory flow 25-75%\ndefinition : A reduction compared to the predicted value of the forced expiratory flow over the middle one-half of the FVC; the average flow from the point at which 25% of the FVC has been exhaled to the point at which 75% of the FVC has been exhaled. Here, the test is performed after the administration of a bronchodilating medication.\nsynonyms :Decreased post bronchodilator forced expiratory flow 25-75%; Decreased post-bronchodilator FEF25-75%; Decreased postbronchodilator forced expiratory flow 25-75%\n'}


{'id': 'HP_0032362', 'url': 'http://purl.obolibrary.org/obo/HP_0032362', 'lbl': 'Increased circulating corticosterone level', 'desc': 'label: Increased circulating corticosterone level\ndefinition : An abnormally elevated concentration of corticosterone in the blood.\nsynonyms :\n'}


{'id': 'HP_0032363', 'url': 'http://purl.obolibrary.org/obo/HP_0032363', 'lbl': 'Decreased circulating corticosterone level', 'desc': 'label: Decreased circulating corticosterone level\ndefinition : An abnormally reduced concentration of corticosterone in the blood.\nsynonyms :\n'}


{'id': 'HP_0032364', 'url': 'http://purl.obolibrary.org/obo/HP_0032364', 'lbl': 'obsolete Abnormal CSF amino acid level', 'desc': 'label: obsolete Abnormal CSF amino acid level\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0032365', 'url': 'http://purl.obolibrary.org/obo/HP_0032365', 'lbl': 'Exacerbated by aspirin ingestion', 'desc': 'label: Exacerbated by aspirin ingestion\ndefinition : Applied to a sign or symptom that is worsened by ingestion of aspirin.\nsynonyms :\n'}


{'id': 'HP_0032366', 'url': 'http://purl.obolibrary.org/obo/HP_0032366', 'lbl': 'Positive direct antiglobulin test', 'desc': 'label: Positive direct antiglobulin test\ndefinition : A positive result of the direct antiglobulin test (DAT), a method of demonstrating the presence of antibody or complement bound to red blood cell (RBC) membranes by the use of anti-human globulin to form a visible agglutination reaction.\nsynonyms :\n'}


{'id': 'HP_0032367', 'url': 'http://purl.obolibrary.org/obo/HP_0032367', 'lbl': 'Abnormal growth hormone level', 'desc': 'label: Abnormal growth hormone level\ndefinition : Any deviation from the normal level of growth hormone (GH) in the blood circulation. GH or somatotropin is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. Its secretion from the pituitary is regulated by the neurosecretory nuclei of the hypothalamus, which can release Growth hormone-releasing hormone (GHRH or somatocrinin) and Growth hormone-inhibiting hormone (GHIH or somatostatin) into the hypophyseal portal venous blood surrounding the pituitary. GH is secreted in a pulsatile manner, which is one of the reasons why an isolated measurement of its blood concentration is not meaningful.\nsynonyms :Abnormal somatotropin level\n'}


{'id': 'HP_0032368', 'url': 'http://purl.obolibrary.org/obo/HP_0032368', 'lbl': 'Acidemia', 'desc': 'label: Acidemia\ndefinition : An abnormally low blood pH (usually defined as less than 7.35).\nsynonyms :\n'}


{'id': 'HP_0032369', 'url': 'http://purl.obolibrary.org/obo/HP_0032369', 'lbl': 'Alkalemia', 'desc': 'label: Alkalemia\ndefinition : An abnormally high blood pH (usually defined as 7.41 or above).\nsynonyms :\n'}


{'id': 'HP_0032370', 'url': 'http://purl.obolibrary.org/obo/HP_0032370', 'lbl': 'Blood group A', 'desc': 'label: Blood group A\ndefinition : ABO phenotype A, corresponding to the genotype AO or AA.\nsynonyms :\n'}


{'id': 'HP_0032371', 'url': 'http://purl.obolibrary.org/obo/HP_0032371', 'lbl': 'Isoleucinuria', 'desc': 'label: Isoleucinuria\ndefinition : An increased concentration of isoleucine in the urine.\nsynonyms :Hyperisoleucinuria; Isoleucine high in urine\n'}


{'id': 'HP_0032372', 'url': 'http://purl.obolibrary.org/obo/HP_0032372', 'lbl': 'Increased peripheral blast count', 'desc': 'label: Increased peripheral blast count\ndefinition : An increased count in the peripheral blood of cells that are precursors to mature circulating blood cells such as neutrophiles, monocytes, lymphocutes, and erythrocytes. Blasts are not usually found in significant numbers in the peripheral blood circulation, but can be observed in hematopoietic neoplasms such as leukemia, severe infections, and as a result of certain medications.\nsynonyms :Elevated blast count; Elevated circulating blasts; Increased peripheral myeloblast count\n'}


{'id': 'HP_0032373', 'url': 'http://purl.obolibrary.org/obo/HP_0032373', 'lbl': 'Duffy blood group', 'desc': 'label: Duffy blood group\ndefinition : The Duffy blood group system is based on the presence of a glycoprotein termed Fy that is on the surface of erythrocytes and some other cells. There are two Duffy antigens named Fya and Fyb, and thus there are four Duffy phenotypes: a+b+, a+b-, a-b+,a-b-.\nsynonyms :\n'}


{'id': 'HP_0032374', 'url': 'http://purl.obolibrary.org/obo/HP_0032374', 'lbl': 'Duffy Fya positivity', 'desc': 'label: Duffy Fya positivity\ndefinition : Presence of the Duffy Fya antigen.\nsynonyms :\n'}


{'id': 'HP_0032375', 'url': 'http://purl.obolibrary.org/obo/HP_0032375', 'lbl': 'Duffy Fyb positivity', 'desc': 'label: Duffy Fyb positivity\ndefinition : Presence of the Duffy Fyb antigen.\nsynonyms :\n'}


{'id': 'HP_0032376', 'url': 'http://purl.obolibrary.org/obo/HP_0032376', 'lbl': 'Anti-beta 2 glycoprotein I antibody positivity', 'desc': 'label: Anti-beta 2 glycoprotein I antibody positivity\ndefinition : Presence of antibodies against beta 2 glycoprotein I in the circulation. Beta-2 glycoprotein I (beta2GPI) is the principal target of autoantibodies in the antiphospholipid syndrome (APS).\nsynonyms :Anti-B2GPI positivity\n'}


{'id': 'HP_0032377', 'url': 'http://purl.obolibrary.org/obo/HP_0032377', 'lbl': 'Increased urinary orosomucoid', 'desc': 'label: Increased urinary orosomucoid\ndefinition : An increased concentration in the urine of alpha-1-acid glycoprotein (AGP), also known as orosomucoid (ORM). AGP is a 41-43-kDa glycoprotein with a pI of 2.8-3.8. AGP is an acute-phase protein that has many activities including, but not limited to, acting as an acute-phase reactant and disease marker, modulating immunity, binding and carrying drugs, maintaining the barrier function of capillary, and mediating the sphingolipid metabolism.\nsynonyms :Increased urinary alpha-1-acid glycoprotein\n'}