{'id': 'HP_3000049', 'url': 'http://purl.obolibrary.org/obo/HP_3000049', 'lbl': 'Abnormal greater palatine artery morphology', 'desc': 'label: Abnormal greater palatine artery morphology\ndefinition : An abnormality of a greater palatine artery.\nsynonyms :Abnormality of greater palatine artery\n'}


{'id': 'HP_3000050', 'url': 'http://purl.obolibrary.org/obo/HP_3000050', 'lbl': 'Abnormal odontoid tissue morphology', 'desc': 'label: Abnormal odontoid tissue morphology\ndefinition : An abnormality of an odontoid tissue.\nsynonyms :Abnormality of hard tissues of teeth; Abnormality of odontoid tissue; Abnormality of tooth hard tissue\n'}


{'id': 'HP_3000051', 'url': 'http://purl.obolibrary.org/obo/HP_3000051', 'lbl': 'Abnormal hyoglossus muscle morphology', 'desc': 'label: Abnormal hyoglossus muscle morphology\ndefinition : An abnormality of a hyoglossus muscle.\nsynonyms :Abnormality of hyoglossus muscle\n'}


{'id': 'HP_3000052', 'url': 'http://purl.obolibrary.org/obo/HP_3000052', 'lbl': 'Abnormal hyoid bone morphology', 'desc': 'label: Abnormal hyoid bone morphology\ndefinition : Any structural abnormality of the hyoid bone (hyoid), a small U-shaped (horseshoe-shaped) solitary bone, situated in the midline of the neck anteriorly at the base of the mandible and posteriorly at the fourth cervical vertebra.\nsynonyms :Abnormality of hyoid bone\n'}


{'id': 'HP_3000053', 'url': 'http://purl.obolibrary.org/obo/HP_3000053', 'lbl': 'Abnormal hypopharynx morphology', 'desc': 'label: Abnormal hypopharynx morphology\ndefinition : A structural anomaly of the hypopharyx, which is the most inferior portion of the pharynx. The hypopharynx continues from the oropharynx at the pharyngoepiglottic fold superiorly and extends inferiorly to the level of the inferior aspect of the cricoid cartilage, which marks the beginning of the cervical esophagus.\nsynonyms :Abnormality of hypopharynx; Abnormality of lower pharynx\n'}


{'id': 'HP_3000054', 'url': 'http://purl.obolibrary.org/obo/HP_3000054', 'lbl': 'Abnormal inferior alveolar artery morphology', 'desc': 'label: Abnormal inferior alveolar artery morphology\ndefinition : An abnormality of an inferior alveolar artery.\nsynonyms :\n'}


{'id': 'HP_3000055', 'url': 'http://purl.obolibrary.org/obo/HP_3000055', 'lbl': 'Abnormality of inferior alveolar nerve', 'desc': 'label: Abnormality of inferior alveolar nerve\ndefinition : An abnormality of an inferior alveolar nerve.\nsynonyms :\n'}


{'id': 'HP_3000056', 'url': 'http://purl.obolibrary.org/obo/HP_3000056', 'lbl': 'Abnormality of artery of lower lip', 'desc': 'label: Abnormality of artery of lower lip\ndefinition : An abnormality of an artery of lower lip.\nsynonyms :Abnormality of the inferior labial artery\n'}


{'id': 'HP_3000057', 'url': 'http://purl.obolibrary.org/obo/HP_3000057', 'lbl': 'Abnormality of inferior oblique extraocular muscle', 'desc': 'label: Abnormality of inferior oblique extraocular muscle\ndefinition : An abnormality of an inferior oblique extraocular muscle.\nsynonyms :Abnormality of the inferior oblique muscle\n'}


{'id': 'HP_3000058', 'url': 'http://purl.obolibrary.org/obo/HP_3000058', 'lbl': 'Abnormality of inferior rectus extraocular muscle', 'desc': 'label: Abnormality of inferior rectus extraocular muscle\ndefinition : An abnormality of an inferior rectus extraocular muscle.\nsynonyms :\n'}


{'id': 'HP_3000059', 'url': 'http://purl.obolibrary.org/obo/HP_3000059', 'lbl': 'Abnormal inferior thyroid vein morphology', 'desc': 'label: Abnormal inferior thyroid vein morphology\ndefinition : An abnormality of an inferior thyroid vein.\nsynonyms :Abnormality of inferior thyroid vein\n'}


{'id': 'HP_3000060', 'url': 'http://purl.obolibrary.org/obo/HP_3000060', 'lbl': 'Abnormal infraorbital artery morphology', 'desc': 'label: Abnormal infraorbital artery morphology\ndefinition : An abnormality of an infraorbital artery.\nsynonyms :Abnormality of infraorbital artery\n'}


{'id': 'HP_3000061', 'url': 'http://purl.obolibrary.org/obo/HP_3000061', 'lbl': 'Abnormality of infra-orbital nerve', 'desc': 'label: Abnormality of infra-orbital nerve\ndefinition : A structural abnormality of an infra-orbital nerve. The infraorbital nerve arises from the maxillary branch of the trigeminal nerve and normally traverses the orbital floor in the infraorbital canal.\nsynonyms :Abnormality of the infraorbital nerve\n'}


{'id': 'HP_3000062', 'url': 'http://purl.obolibrary.org/obo/HP_3000062', 'lbl': 'Abnormal internal carotid artery morphology', 'desc': 'label: Abnormal internal carotid artery morphology\ndefinition : An abnormality of an internal carotid artery.\nsynonyms :Abnormality of internal carotid artery\n'}


{'id': 'HP_3000063', 'url': 'http://purl.obolibrary.org/obo/HP_3000063', 'lbl': 'Abnormality of internal jugular vein', 'desc': 'label: Abnormality of internal jugular vein\ndefinition : An abnormality of an internal jugular vein.\nsynonyms :\n'}


{'id': 'HP_3000064', 'url': 'http://purl.obolibrary.org/obo/HP_3000064', 'lbl': 'Abnormality of intrinsic muscle of tongue', 'desc': 'label: Abnormality of intrinsic muscle of tongue\ndefinition : An abnormality of an intrinsic muscle of tongue.\nsynonyms :Abnormality of intrinsic lingual muscle\n'}


{'id': 'HP_3000065', 'url': 'http://purl.obolibrary.org/obo/HP_3000065', 'lbl': 'Abnormal lacrimal artery morphology', 'desc': 'label: Abnormal lacrimal artery morphology\ndefinition : An abnormality of a lacrimal artery.\nsynonyms :Abnormality of lacrimal artery\n'}


{'id': 'HP_3000066', 'url': 'http://purl.obolibrary.org/obo/HP_3000066', 'lbl': 'Abnormal lacrimal sac morphology', 'desc': 'label: Abnormal lacrimal sac morphology\ndefinition : An abnormality of a lacrimal sac.\nsynonyms :Abnormality of lacrimal sac\n'}


{'id': 'HP_3000067', 'url': 'http://purl.obolibrary.org/obo/HP_3000067', 'lbl': 'Abnormal lateral cricoarytenoid muscle morphology', 'desc': 'label: Abnormal lateral cricoarytenoid muscle morphology\ndefinition : Any structural abnormality of a lateral crico-arytenoid muscle, which extends from the lateral cricoid cartilage to the muscular process of the arytenoid cartilage, and can adduct the vocal cords, which closes the rima glottidis and thereby protects the airway.\nsynonyms :Abnormal anterior cricoarytenoid muscle morphology; Abnormality of lateral crico-arytenoid; Abnormality of lateral cricoarytenoid muscle\n'}


{'id': 'HP_3000068', 'url': 'http://purl.obolibrary.org/obo/HP_3000068', 'lbl': 'Abnormality of lateral pterygoid muscle', 'desc': 'label: Abnormality of lateral pterygoid muscle\ndefinition : An abnormality of a lateral pterygoid muscle.\nsynonyms :\n'}


{'id': 'HP_3000069', 'url': 'http://purl.obolibrary.org/obo/HP_3000069', 'lbl': 'Abnormality of lateral rectus extra-ocular muscle', 'desc': 'label: Abnormality of lateral rectus extra-ocular muscle\ndefinition : An abnormality of a lateral rectus extra-ocular muscle.\nsynonyms :\n'}


{'id': 'HP_3000070', 'url': 'http://purl.obolibrary.org/obo/HP_3000070', 'lbl': 'Abnormality of levator anguli oris', 'desc': 'label: Abnormality of levator anguli oris\ndefinition : An abnormality of a levator anguli oris.\nsynonyms :\n'}


{'id': 'HP_3000071', 'url': 'http://purl.obolibrary.org/obo/HP_3000071', 'lbl': 'Abnormality of levator labii superioris', 'desc': 'label: Abnormality of levator labii superioris\ndefinition : An abnormality of a levator labii superioris.\nsynonyms :\n'}


{'id': 'HP_3000072', 'url': 'http://purl.obolibrary.org/obo/HP_3000072', 'lbl': 'Abnormal levator palpebrae superioris morphology', 'desc': 'label: Abnormal levator palpebrae superioris morphology\ndefinition : An abnormality of a levator palpebrae superioris.\nsynonyms :\n'}


{'id': 'HP_3000073', 'url': 'http://purl.obolibrary.org/obo/HP_3000073', 'lbl': 'Abnormality of levator veli palatini muscle', 'desc': 'label: Abnormality of levator veli palatini muscle\ndefinition : An abnormality of a levator veli palatini.\nsynonyms :\n'}


{'id': 'HP_3000074', 'url': 'http://purl.obolibrary.org/obo/HP_3000074', 'lbl': 'Abnormal lingual artery morphology', 'desc': 'label: Abnormal lingual artery morphology\ndefinition : Any structural abnormality of a lingual artery.\nsynonyms :Abnormality of lingual artery\n'}


{'id': 'HP_3000075', 'url': 'http://purl.obolibrary.org/obo/HP_3000075', 'lbl': 'Abnormal lingual nerve morphology', 'desc': 'label: Abnormal lingual nerve morphology\ndefinition : Any structural anomaly of a lingual nerve.\nsynonyms :Abnormality of lingual nerve\n'}


{'id': 'HP_3000076', 'url': 'http://purl.obolibrary.org/obo/HP_3000076', 'lbl': 'Abnormality of lingual tonsil', 'desc': 'label: Abnormality of lingual tonsil\ndefinition : An abnormality of a lingual tonsil.\nsynonyms :\n'}


{'id': 'HP_3000077', 'url': 'http://purl.obolibrary.org/obo/HP_3000077', 'lbl': 'Abnormal mandible condylar process morphology', 'desc': 'label: Abnormal mandible condylar process morphology\ndefinition : An abnormality of a mandible condylar process.\nsynonyms :Abnormality of mandible condylar process\n'}


{'id': 'HP_3000078', 'url': 'http://purl.obolibrary.org/obo/HP_3000078', 'lbl': 'Abnormal mandible coronoid process morphology', 'desc': 'label: Abnormal mandible coronoid process morphology\ndefinition : An abnormality of a mandible coronoid process.\nsynonyms :Abnormality of mandible coronoid process\n'}


{'id': 'HP_3000079', 'url': 'http://purl.obolibrary.org/obo/HP_3000079', 'lbl': 'Abnormal mandibular symphysis morphology', 'desc': 'label: Abnormal mandibular symphysis morphology\ndefinition : A structural abnormality of a mandibular symphysis.\nsynonyms :Abnormality of mandible symphysis\n'}


{'id': 'HP_4000001', 'url': 'http://purl.obolibrary.org/obo/HP_4000001', 'lbl': 'Abnormal cardiac magnetic resonance imaging finding', 'desc': 'label: Abnormal cardiac magnetic resonance imaging finding\ndefinition : Abnormal finding by magnetic resonance imaging (MRI), which uses non-ionizing radiation via a strong magnetic field and radio frequency energy to generate three dimensional images. This term comprises findings that are specific to MRI. Findings such as ventricular spetum defect that can be detected by multiple modalities should be coded separately.\nsynonyms :\n'}


{'id': 'HP_4000003', 'url': 'http://purl.obolibrary.org/obo/HP_4000003', 'lbl': 'Elevated myocardial native T2', 'desc': 'label: Elevated myocardial native T2\ndefinition : Increased duration of myocardial T2 time without gadolinium contrast. Elevated T2, which can detect myocardial edema.\nsynonyms :\n'}


{'id': 'HP_4000004', 'url': 'http://purl.obolibrary.org/obo/HP_4000004', 'lbl': 'Myocardial late gadolinium enhancement', 'desc': 'label: Myocardial late gadolinium enhancement\ndefinition : Areas of high signal intensity in magnetic resonance imaging of the heart appearing 10 to 15 minutes after injection of the intercellular contrast agent gadolinium.\nsynonyms :Delayed myocardial gadolinium enhancement\n'}


{'id': 'HP_4000005', 'url': 'http://purl.obolibrary.org/obo/HP_4000005', 'lbl': 'Pericardial late gadolinium enhancement', 'desc': 'label: Pericardial late gadolinium enhancement\ndefinition : Areas of high signal intensity in magnetic resonance imaging of the pericardium appearing around 10 minutes after injection of the intercellular contrast agent gadolinium.\nsynonyms :\n'}


{'id': 'HP_4000006', 'url': 'http://purl.obolibrary.org/obo/HP_4000006', 'lbl': 'Elevated myocardial native T1', 'desc': 'label: Elevated myocardial native T1\ndefinition : Increased duration of myocardial T1 time without gadolinium contrast. T1 mapping consists of quantifying the T1 relaxation time of a tissue by using analytical expressions of image-based signal intensities. A fundamental principle of MR imaging is that the signal intensity of pixels is based on the relaxation of hydrogen nuclei protons in a static magnetic field. The T1 relaxation times between two tissues vary substantially. Edema, fat infiltration, and fibrosis also cause differences in T1 relaxivity.\nsynonyms :Prolonged myocardial native T1\n'}


{'id': 'HP_4000007', 'url': 'http://purl.obolibrary.org/obo/HP_4000007', 'lbl': 'Bronchoconstriction', 'desc': 'label: Bronchoconstriction\ndefinition : Tightening of smooth muscle surrounding the bronchi and bronchioles with consequent wheezing and shortness of breath.\nsynonyms :Bronchial constriction; Constriction of the bronchi\n'}


{'id': 'HP_4000008', 'url': 'http://purl.obolibrary.org/obo/HP_4000008', 'lbl': 'Formation of multiple pronuclei during fertilization', 'desc': 'label: Formation of multiple pronuclei during fertilization\ndefinition : Pronuclei formation is a critical process during fertilisation. Normally, there are two pronuclei (2PN), including the paternal pronucleus and the maternal pronucleus, in the zygote after fertilisation. It is generally accepted that multiple pronuclei (MPN) formation is due to the abnormal extrusion of the second polar body or to abnormal fertilisation with multiple sperm. The MPN therefore can cause infertility and recurrent failure of IVF/ICSI.\nsynonyms :\n'}


{'id': 'HP_4000009', 'url': 'http://purl.obolibrary.org/obo/HP_4000009', 'lbl': 'Kinesiophobia', 'desc': 'label: Kinesiophobia\ndefinition : An excessive, irrational and debilitating fear to carry out a physical movement, due to a feeling of vulnerability to a painful injury or reinjury.\nsynonyms :\n'}


{'id': 'HP_4000010', 'url': 'http://purl.obolibrary.org/obo/HP_4000010', 'lbl': 'Impaired renal tubular reabsorption of bicarbonate', 'desc': 'label: Impaired renal tubular reabsorption of bicarbonate\ndefinition : Decreased renal tubular reabsorption of bicarbonate.\nsynonyms :\n'}


{'id': 'HP_4000011', 'url': 'http://purl.obolibrary.org/obo/HP_4000011', 'lbl': 'History of congenital HPV infection', 'desc': 'label: History of congenital HPV infection\ndefinition : A congenital human papillomavirus (HPV) infection of the newborn. Congential HPV infection can manifest as condyloma cuminata in the newborn.\nsynonyms :\n'}


{'id': 'HP_4000012', 'url': 'http://purl.obolibrary.org/obo/HP_4000012', 'lbl': 'Necrotizing ileitis', 'desc': 'label: Necrotizing ileitis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_4000013', 'url': 'http://purl.obolibrary.org/obo/HP_4000013', 'lbl': 'Anti-desmoglein-1 antibody positivity', 'desc': 'label: Anti-desmoglein-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against desmoglein-1, a dermal cell adhesion molecule.\nsynonyms :\n'}


{'id': 'HP_4000014', 'url': 'http://purl.obolibrary.org/obo/HP_4000014', 'lbl': 'Anti-desmoglein-3 antibody positivity', 'desc': 'label: Anti-desmoglein-3 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against desmoglein-3, a dermal cell adhesion molecule.\nsynonyms :\n'}


{'id': 'HP_4000015', 'url': 'http://purl.obolibrary.org/obo/HP_4000015', 'lbl': 'Anti-envoplakin antibody positivity', 'desc': 'label: Anti-envoplakin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against envoplakin, a cytoskeletal linker protein that links intermediate filaments to cellular junctions.\nsynonyms :\n'}


{'id': 'HP_4000016', 'url': 'http://purl.obolibrary.org/obo/HP_4000016', 'lbl': 'Anti-periplakin antibody positivity', 'desc': 'label: Anti-periplakin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against periplakin.\nsynonyms :\n'}


{'id': 'HP_4000017', 'url': 'http://purl.obolibrary.org/obo/HP_4000017', 'lbl': 'Anti-desmoplakin I antibody positivity', 'desc': 'label: Anti-desmoplakin I antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against desmoplakin-1.\nsynonyms :\n'}


{'id': 'HP_4000018', 'url': 'http://purl.obolibrary.org/obo/HP_4000018', 'lbl': 'Anti-desmoplakin II antibody positivity', 'desc': 'label: Anti-desmoplakin II antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against desmoplakin-II.\nsynonyms :\n'}


{'id': 'HP_4000019', 'url': 'http://purl.obolibrary.org/obo/HP_4000019', 'lbl': 'Anti-BP230 antibody positivity', 'desc': 'label: Anti-BP230 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against BP230.\nsynonyms :\n'}


{'id': 'HP_4000020', 'url': 'http://purl.obolibrary.org/obo/HP_4000020', 'lbl': 'Anti-BP180 antibody positivity', 'desc': 'label: Anti-BP180 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against BP180.\nsynonyms :\n'}


{'id': 'HP_4000021', 'url': 'http://purl.obolibrary.org/obo/HP_4000021', 'lbl': 'Anti-laminin 332 antibody positivity', 'desc': 'label: Anti-laminin 332 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against laminin-332.\nsynonyms :Anti-laminin 5 antibody positivity\n'}


{'id': 'HP_4000022', 'url': 'http://purl.obolibrary.org/obo/HP_4000022', 'lbl': 'Anti-laminin 6 antibody positivity', 'desc': 'label: Anti-laminin 6 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against laminin-6.\nsynonyms :\n'}


{'id': 'HP_4000023', 'url': 'http://purl.obolibrary.org/obo/HP_4000023', 'lbl': 'Anti-laminin gamma1 antibody positivity', 'desc': 'label: Anti-laminin gamma1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against laminin gamma-1.\nsynonyms :\n'}


{'id': 'HP_4000024', 'url': 'http://purl.obolibrary.org/obo/HP_4000024', 'lbl': 'Anti-laminin antibody positivity', 'desc': 'label: Anti-laminin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against a laminin. Laminins are major components of the basement membrane.\nsynonyms :\n'}


{'id': 'HP_4000025', 'url': 'http://purl.obolibrary.org/obo/HP_4000025', 'lbl': 'Anti-integrin antibody positivity', 'desc': 'label: Anti-integrin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against an integrin. Integrins are a family of cell adhesion molecules with 24 known integrin heterodimers. Integrins transduce mechanical and biochemical signals from fibrotic extracellular matrix into the cell, activate latent TGFbeta, and subsequently modulate fibroblast adhesion, migration, and growth.\nsynonyms :\n'}


{'id': 'HP_4000026', 'url': 'http://purl.obolibrary.org/obo/HP_4000026', 'lbl': 'Anti-transglutaminase 6 antibody', 'desc': 'label: Anti-transglutaminase 6 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against transglutaminase 6.\nsynonyms :\n'}


{'id': 'HP_4000027', 'url': 'http://purl.obolibrary.org/obo/HP_4000027', 'lbl': 'anti-LAD-1 antibody positivity', 'desc': 'label: anti-LAD-1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against LAD-1, which is the soluble 120 kDa ectodomain of BP180.\nsynonyms :\n'}


{'id': 'HP_4000028', 'url': 'http://purl.obolibrary.org/obo/HP_4000028', 'lbl': 'Anti-LABD97 antibody positivity', 'desc': 'label: Anti-LABD97 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against LABD97, which is structurally identical to a portion of the extracellular domain of BPAg2. BPAg2, a 180 kDa bullous pemphigoid antigen, is a transmembrane protein important for basement membrane cohesion.\nsynonyms :\n'}


{'id': 'HP_4000029', 'url': 'http://purl.obolibrary.org/obo/HP_4000029', 'lbl': 'Antigliadin antibody positivity', 'desc': 'label: Antigliadin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against gliadin.\nsynonyms :AGA autoantibodies\n'}


{'id': 'HP_4000030', 'url': 'http://purl.obolibrary.org/obo/HP_4000030', 'lbl': 'Anti-reticulin antibody positivity', 'desc': 'label: Anti-reticulin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against reticulin.\nsynonyms :\n'}


{'id': 'HP_4000031', 'url': 'http://purl.obolibrary.org/obo/HP_4000031', 'lbl': 'Anti-type VII collagen antibody', 'desc': 'label: Anti-type VII collagen antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against collagen type VII.\nsynonyms :\n'}


{'id': 'HP_4000032', 'url': 'http://purl.obolibrary.org/obo/HP_4000032', 'lbl': 'False perception of self-motion', 'desc': "label: False perception of self-motion\ndefinition : A perception that one's body is moving or swaying despite lack of motion of the body.\nsynonyms :\n"}


{'id': 'HP_4000033', 'url': 'http://purl.obolibrary.org/obo/HP_4000033', 'lbl': 'Non-spinning vertigo', 'desc': 'label: Non-spinning vertigo\ndefinition : A perception of unsteadiness of dizziness that is not characterized bythe spinning sensation of classic vertigo, but rather by an oscillatory perception (rocking, bobbing, or swaying despite the fact that the subject is not moving).\nsynonyms :\n'}


{'id': 'HP_4000034', 'url': 'http://purl.obolibrary.org/obo/HP_4000034', 'lbl': 'Infection-associated lymphopenia', 'desc': 'label: Infection-associated lymphopenia\ndefinition : Decreased lymphocyte count during infections.\nsynonyms :Infection-associated lymphocytopenia\n'}


{'id': 'HP_4000035', 'url': 'http://purl.obolibrary.org/obo/HP_4000035', 'lbl': 'Primary obstructive megaureter', 'desc': 'label: Primary obstructive megaureter\ndefinition : Megaurater associated with obstruction or an adynamic ureteral segment in the ureterovesical junction.\nsynonyms :\n'}


{'id': 'HP_4000036', 'url': 'http://purl.obolibrary.org/obo/HP_4000036', 'lbl': 'Encysted hydrocele of the cord', 'desc': 'label: Encysted hydrocele of the cord\ndefinition : A type of hydrocele testis in which both the proximal and distal portions of processus vaginalis get obliterated while the central portion remains patent and fluid accumulates within it.\nsynonyms :\n'}


{'id': 'HP_4000037', 'url': 'http://purl.obolibrary.org/obo/HP_4000037', 'lbl': 'Congenital hydrocele', 'desc': 'label: Congenital hydrocele\ndefinition : Congenital hydrocele occurs when processus vaginalis is patent and communicates with the peritoneal cavity. This communication allows the movement of peritoneal fluid but is too small to allow the intra-abdominal contents to herniate through.\nsynonyms :\n'}


{'id': 'HP_4000038', 'url': 'http://purl.obolibrary.org/obo/HP_4000038', 'lbl': 'Infantile hydrocele', 'desc': 'label: Infantile hydrocele\ndefinition : Infantile Hydrocele is a type pf hydrocele in which the processus vaginalis gets obliterated at the level of the deep inguinal ring. However, the portion distal to it remains patent and allows fluid accumulation.\nsynonyms :\n'}


{'id': 'HP_4000039', 'url': 'http://purl.obolibrary.org/obo/HP_4000039', 'lbl': 'Reduced proportion of mucosal-associated invariant T cells', 'desc': 'label: Reduced proportion of mucosal-associated invariant T cells\ndefinition : A decreased proportion of circulating mucosal-associated invariant T (MAIT) cells relative to total T cell count.\nsynonyms :\n'}


{'id': 'HP_4000040', 'url': 'http://purl.obolibrary.org/obo/HP_4000040', 'lbl': 'Puerpural onset', 'desc': 'label: Puerpural onset\ndefinition : Onset of a phenotypic abnormality or a disease during childbirth or in the period immediately following.\nsynonyms :\n'}


{'id': 'HP_4000041', 'url': 'http://purl.obolibrary.org/obo/HP_4000041', 'lbl': 'AA amyloidosis', 'desc': 'label: AA amyloidosis\ndefinition : Extracellular tissue deposition of fibrils that are composed of fragments of and/or intact serum amyloid A protein, a hepatic acute phase reactant.\nsynonyms :\n'}


{'id': 'HP_4000042', 'url': 'http://purl.obolibrary.org/obo/HP_4000042', 'lbl': 'Fracture type', 'desc': 'label: Fracture type\ndefinition : Category of fracture. Terms from this subontology can be used together with terms in the subontology that descends from Bone fracture (HP:0020110).\nsynonyms :\n'}


{'id': 'HP_4000043', 'url': 'http://purl.obolibrary.org/obo/HP_4000043', 'lbl': 'Greenstick fracture', 'desc': 'label: Greenstick fracture\ndefinition : A type of fracture in which the broken bone is not completely separated.\nsynonyms :Incomplete fracture\n'}


{'id': 'HP_4000044', 'url': 'http://purl.obolibrary.org/obo/HP_4000044', 'lbl': 'Transverse fracture', 'desc': 'label: Transverse fracture\ndefinition : A type of fracture in which the break is in a straight line across the bone.\nsynonyms :\n'}


{'id': 'HP_4000045', 'url': 'http://purl.obolibrary.org/obo/HP_4000045', 'lbl': 'Spiral fracture', 'desc': 'label: Spiral fracture\ndefinition : A type of fracture in which the break spirals around the bone.\nsynonyms :\n'}


{'id': 'HP_4000046', 'url': 'http://purl.obolibrary.org/obo/HP_4000046', 'lbl': 'Oblique fracture', 'desc': 'label: Oblique fracture\ndefinition : A type of fracture in which there is a diagonal break across the bone.\nsynonyms :\n'}


{'id': 'HP_4000047', 'url': 'http://purl.obolibrary.org/obo/HP_4000047', 'lbl': 'Compression fracture', 'desc': 'label: Compression fracture\ndefinition : A type of fracture in which the bone is crushed, causing the broken bone to be wider or flatter in appearance.\nsynonyms :Wedge fracture\n'}


{'id': 'HP_4000048', 'url': 'http://purl.obolibrary.org/obo/HP_4000048', 'lbl': 'Comminuted fracture', 'desc': 'label: Comminuted fracture\ndefinition : A type of fracture in which the break is in three or more pieces and fragments are present at the fracture site.\nsynonyms :\n'}


{'id': 'HP_4000049', 'url': 'http://purl.obolibrary.org/obo/HP_4000049', 'lbl': 'Segmental fracture', 'desc': 'label: Segmental fracture\ndefinition : A type of fracture in which the same bone is fractured in two places, so there is a floating segment of bone.\nsynonyms :\n'}


{'id': 'HP_4000050', 'url': 'http://purl.obolibrary.org/obo/HP_4000050', 'lbl': 'Open fracture', 'desc': 'label: Open fracture\ndefinition : A type of fracture in which there is an open wound or break in the skin near the site of the broken bone.\nsynonyms :Compound fracture\n'}


{'id': 'HP_4000051', 'url': 'http://purl.obolibrary.org/obo/HP_4000051', 'lbl': 'Closed fracture', 'desc': 'label: Closed fracture\ndefinition : A type of fracture in which the broken bone that does not penetrate the skin.\nsynonyms :\n'}


{'id': 'HP_4000052', 'url': 'http://purl.obolibrary.org/obo/HP_4000052', 'lbl': 'Avulsion fracture', 'desc': 'label: Avulsion fracture\ndefinition : A type of fracture that is localied near to a a tendon or ligament and a small fragment of bone is separated from the main mass of bone as a result of physical trauma.\nsynonyms :\n'}


{'id': 'HP_4000053', 'url': 'http://purl.obolibrary.org/obo/HP_4000053', 'lbl': 'Displaced fracture', 'desc': 'label: Displaced fracture\ndefinition : A type of fracture in which the ends of the fractured bone are no longer aligned.\nsynonyms :\n'}


{'id': 'HP_4000054', 'url': 'http://purl.obolibrary.org/obo/HP_4000054', 'lbl': 'Exanthem', 'desc': 'label: Exanthem\ndefinition : A widespread rash.\nsynonyms :\n'}


{'id': 'HP_4000055', 'url': 'http://purl.obolibrary.org/obo/HP_4000055', 'lbl': 'Intestinal inflammation', 'desc': 'label: Intestinal inflammation\ndefinition : A reaction characterizeds by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling localized to the in the intestinal tract.\nsynonyms :\n'}


{'id': 'HP_4000056', 'url': 'http://purl.obolibrary.org/obo/HP_4000056', 'lbl': 'Abnormal apoptosis', 'desc': 'label: Abnormal apoptosis\ndefinition : Any abnormality of programmed cell death (apoptosis), which is defined as the orchestrated collapse of a cell characterised by membrane blebbing, cell shrinkage, condensation of chromatin, and fragmentation of DNA followed by rapid engulfment of the corpse by neighbouring cells. Apoptosis is distinguished from death by necrosis by the absence of an associated inflammatory response.\nsynonyms :\n'}


{'id': 'HP_4000057', 'url': 'http://purl.obolibrary.org/obo/HP_4000057', 'lbl': 'Decreased FasL-mediated apoptosis', 'desc': 'label: Decreased FasL-mediated apoptosis\ndefinition : A reduced amount of programmed cell death upon stimulation of the FAS receptor, which normally induces caspase-8 dependent apoptosis.\nsynonyms :\n'}


{'id': 'HP_4000058', 'url': 'http://purl.obolibrary.org/obo/HP_4000058', 'lbl': 'Glomerular proteinuria', 'desc': 'label: Glomerular proteinuria\ndefinition : A type of proteinuria characterized by increased permeability of the glomerular capillary wall to macromolecules (particularly albumin), whereby protein excretion can reach 20 g/24 h and consists mainly of albumin. \nPMID: 19634399\nsynonyms :\n'}


{'id': 'HP_4000059', 'url': 'http://purl.obolibrary.org/obo/HP_4000059', 'lbl': 'Abnormal lung development', 'desc': 'label: Abnormal lung development\ndefinition : A structural defect associated with abnormal development of the lung.\nsynonyms :Developmental pulmonary anomaly\n'}


{'id': 'HP_4000060', 'url': 'http://purl.obolibrary.org/obo/HP_4000060', 'lbl': 'Abnormal pulmonary alveolar system development', 'desc': 'label: Abnormal pulmonary alveolar system development\ndefinition : \nsynonyms :\n'}


{'id': 'HP_4000061', 'url': 'http://purl.obolibrary.org/obo/HP_4000061', 'lbl': 'Pancreatic alpha-cell hyperplasia', 'desc': 'label: Pancreatic alpha-cell hyperplasia\ndefinition : A diffuse and specific increase in the number of alpha-cells.\nsynonyms :\n'}


{'id': 'HP_4000062', 'url': 'http://purl.obolibrary.org/obo/HP_4000062', 'lbl': '3-4 metacarpal synostosis', 'desc': 'label: 3-4 metacarpal synostosis\ndefinition : A congenital hand malformation characterized by the coalescence of the coalescence of third and fourth metacarpals (i.e., those corresponding to the middle and ring fingers).\nsynonyms :Fused third and fourth metacarpals; Middle and ring finger metacarpal synostosis; Synostosis of third and the fourth metacarpal bones\n'}


{'id': 'HP_4000066', 'url': 'http://purl.obolibrary.org/obo/HP_4000066', 'lbl': 'Abnormal iliac artery morphology', 'desc': 'label: Abnormal iliac artery morphology\ndefinition : Any structural anomaly of the iliac artery.\nsynonyms :\n'}


{'id': 'HP_4000067', 'url': 'http://purl.obolibrary.org/obo/HP_4000067', 'lbl': 'Iliac artery aneurysm', 'desc': 'label: Iliac artery aneurysm\ndefinition : Abnormal outpouching or sac-like dilatation in the iliac artery.\nsynonyms :\n'}


{'id': 'HP_4000068', 'url': 'http://purl.obolibrary.org/obo/HP_4000068', 'lbl': 'Abnormal interest', 'desc': "label: Abnormal interest\ndefinition : Any deviation from normal intensity or subject of a person's interests, which can be defined as a state of giving selective attention to something.\nsynonyms :\n"}


{'id': 'HP_4000069', 'url': 'http://purl.obolibrary.org/obo/HP_4000069', 'lbl': 'Persistent preoccupation with parts of objects or unusual objects', 'desc': 'label: Persistent preoccupation with parts of objects or unusual objects\ndefinition : A type of abnormal interest characterized by a persistent and intense focus on parts of a toy/object. For example, affected individuals may spin the wheels on a toy car rather than driving the toy car.\nsynonyms :Fixated interest in unusual objects; Fixated interest with parts of objects; Fixation with parts of objects\n'}


{'id': 'HP_4000070', 'url': 'http://purl.obolibrary.org/obo/HP_4000070', 'lbl': 'Fixated interests', 'desc': 'label: Fixated interests\ndefinition : Highly restricted, fixated interests that are abnormal in intensity or focus (e.g., strong attachment to or preoccupation with unusual objects, excessively circumscribed or perseverative interests).\nsynonyms :Circumscribed interests; Restricted interests\n'}


{'id': 'HP_4000072', 'url': 'http://purl.obolibrary.org/obo/HP_4000072', 'lbl': 'Abnormal language feature', 'desc': 'label: Abnormal language feature\ndefinition : The presence of any atypical form of expressive language.\nsynonyms :\n'}


{'id': 'HP_4000073', 'url': 'http://purl.obolibrary.org/obo/HP_4000073', 'lbl': 'Pronoun reversal', 'desc': "label: Pronoun reversal\ndefinition : Atypical language feature charaterized by first vs. second or third person pronoun errors such as using 'you' or 'he/she' in place of 'I'.\nsynonyms :\n"}


{'id': 'HP_4000074', 'url': 'http://purl.obolibrary.org/obo/HP_4000074', 'lbl': 'Idiosyncratic language', 'desc': 'label: Idiosyncratic language\ndefinition : Inappropriate use of words that have no phonological or semantic similarity to the intended word.\nsynonyms :\n'}


{'id': 'HP_4000075', 'url': 'http://purl.obolibrary.org/obo/HP_4000075', 'lbl': 'Reduced frequency of facial expressions', 'desc': 'label: Reduced frequency of facial expressions\ndefinition : The number of times facial expressions are produced in a given period is lower than expected given the social and cultural context.\nsynonyms :\n'}


{'id': 'HP_4000076', 'url': 'http://purl.obolibrary.org/obo/HP_4000076', 'lbl': "Use of another person's body to communicate", 'desc': "label: Use of another person's body to communicate\ndefinition : Moving another person's hand, body part, or body to communicate a desire, e.g. pushing or pulling someone toward a desired object or placing someone's hand on something.\nsynonyms :Hand-leading gesture; Hand-taking gestures\n"}


{'id': 'HP_4000077', 'url': 'http://purl.obolibrary.org/obo/HP_4000077', 'lbl': 'Fixated interest with abnormal focus', 'desc': 'label: Fixated interest with abnormal focus\ndefinition : A fixated interest in a specific topic that is atypical for the social context of the individual, such as topics of a non-social nature like fossils or vacuum cleaners.\nsynonyms :\n'}


{'id': 'HP_4000078', 'url': 'http://purl.obolibrary.org/obo/HP_4000078', 'lbl': 'Fixated interest with abnormal intensity', 'desc': 'label: Fixated interest with abnormal intensity\ndefinition : An abnormally intense interest in a topic or object that is not atypical for the social context of the affected person.\nsynonyms :\n'}


{'id': 'HP_4000079', 'url': 'http://purl.obolibrary.org/obo/HP_4000079', 'lbl': 'Sensory seeking', 'desc': 'label: Sensory seeking\ndefinition : Unusual interest in sensory aspects of the environment.\nsynonyms :\n'}


{'id': 'HP_4000080', 'url': 'http://purl.obolibrary.org/obo/HP_4000080', 'lbl': 'Reduced social initiation', 'desc': 'label: Reduced social initiation\ndefinition : Failure of a person to initiate social interactions with others. For a social interaction to have been initiated by someone, there must have been an absence of social interactions from either party for a period. The interaction must also be unprompted by another party.\nsynonyms :\n'}


{'id': 'HP_4000081', 'url': 'http://purl.obolibrary.org/obo/HP_4000081', 'lbl': 'Reduced production of gestures', 'desc': 'label: Reduced production of gestures\ndefinition : Diminished use of typical non-verbal conversational gestures such as shaking the head to indicate no or nodding the head to indicate yes.\nsynonyms :\n'}


{'id': 'HP_4000082', 'url': 'http://purl.obolibrary.org/obo/HP_4000082', 'lbl': 'Reduced collaborative play', 'desc': "label: Reduced collaborative play\ndefinition : Impairment in a child's ability to be able to play in a way that involves peer collaboration. Collaborative play involves things such as verbal and non-verbal communication (e.g., self-initiated interactions), turn-taking, sharing, reciprocity, and collaborative problem-solving. It is often contrasted to parallel play, which involves a form of social play in which two children do similar activities near each other and often mimic each other. Typically developing children develop collaborative play between the ages of 4 and 5.\nsynonyms :\n"}


{'id': 'HP_4000083', 'url': 'http://purl.obolibrary.org/obo/HP_4000083', 'lbl': 'Reduced interest in peers', 'desc': 'label: Reduced interest in peers\ndefinition : Lack of interest of an individual in peers of comparable age and social groups. For example, a child who is only interested in social interactions with adults rather than children their age.\nsynonyms :\n'}


{'id': 'HP_4000084', 'url': 'http://purl.obolibrary.org/obo/HP_4000084', 'lbl': 'Reduced sharing of interests', 'desc': 'label: Reduced sharing of interests\ndefinition : Decreased sharing of interests with others.\nsynonyms :\n'}


{'id': 'HP_4000085', 'url': 'http://purl.obolibrary.org/obo/HP_4000085', 'lbl': 'Reduced object sharing', 'desc': 'label: Reduced object sharing\ndefinition : An absence or reduction in object sharing. Object sharing is an early emerging social skill in which a child will share objects with parents or peers during object play. Object sharing typically develops within the first two years of life.\nsynonyms :\n'}


{'id': 'HP_4000087', 'url': 'http://purl.obolibrary.org/obo/HP_4000087', 'lbl': 'Abnormal communicative facial expressions', 'desc': 'label: Abnormal communicative facial expressions\ndefinition : Abnormal expressions (movements or position of muscles of the face that convey the emotional state of an individual to observers during social interactions) comprising abnormalities of quantity, range, context-appropriateness, and quality.\nsynonyms :Abnormal facial expression use\n'}


{'id': 'HP_4000088', 'url': 'http://purl.obolibrary.org/obo/HP_4000088', 'lbl': 'Facial expressions that do not match the context', 'desc': 'label: Facial expressions that do not match the context\ndefinition : Production of facial expressions that are misaligned with the social context.\nsynonyms :\n'}


{'id': 'HP_4000089', 'url': 'http://purl.obolibrary.org/obo/HP_4000089', 'lbl': 'Abnormal quality of facial expression', 'desc': 'label: Abnormal quality of facial expression\ndefinition : Spontaneous production of communicative facial expressions that have poor quality or are exaggerated or muted.\nsynonyms :Atypical facial expressions\n'}


{'id': 'HP_4000090', 'url': 'http://purl.obolibrary.org/obo/HP_4000090', 'lbl': 'Abnormal gesture use', 'desc': 'label: Abnormal gesture use\ndefinition : Abnormality in use of gestures defined as hand, shoulder, and head movements that convey a shared meaning within a culture that replace or supplement verbal communication.\nsynonyms :Abnormal communicative gesture use; Abnormal communicative gestures; Abnormal gestures\n'}


{'id': 'HP_4000092', 'url': 'http://purl.obolibrary.org/obo/HP_4000092', 'lbl': 'Poor conversational reciprocity', 'desc': 'label: Poor conversational reciprocity\ndefinition : Reduced ability to conduct a reciprocal (back and forth) conversation, as expected for language level. May be characterized by deficits in the ability to make comments about discussion topics of others, failure to ask questions, and not building a conversation on comments of others. Affected persons may not know what to say next in a conversation, may not notice if others are bored with a given topic, may conduct a one-sided conversation (talking but not listening), or may veer off topic more than is socially acceptable.\nsynonyms :Failure of normal back-and-forth conversation\n'}


{'id': 'HP_4000093', 'url': 'http://purl.obolibrary.org/obo/HP_4000093', 'lbl': 'Ectopic tooth eruption', 'desc': 'label: Ectopic tooth eruption\ndefinition : A condition in which the permanent teeth, because of deficiency of growth in the jaw or segment of jaw, assume a path of eruption that intercepts a primary tooth, causes its premature loss and produces a consequent malposition of the permanent tooth.\nsynonyms :\n'}


{'id': 'HP_4000094', 'url': 'http://purl.obolibrary.org/obo/HP_4000094', 'lbl': 'Corpus cavernosum hypoplasia', 'desc': 'label: Corpus cavernosum hypoplasia\ndefinition : A developmental anomaly characterized by undergrowth of the corpus cavernosum.\nsynonyms :\n'}


{'id': 'HP_4000095', 'url': 'http://purl.obolibrary.org/obo/HP_4000095', 'lbl': 'Elevated circulating thymine concentration', 'desc': 'label: Elevated circulating thymine concentration\ndefinition : Concentration of the nucleobase thymine in the blood circulation above the normal range.\nsynonyms :\n'}


{'id': 'HP_4000100', 'url': 'http://purl.obolibrary.org/obo/HP_4000100', 'lbl': 'Positive lactose hydrogen breath test', 'desc': 'label: Positive lactose hydrogen breath test\ndefinition : Elevated hydrogen gas level in exhaled breath following oral administration of lactose. In individuals with lactose intolerance, undigested lactose in the colon will be metabolized by colonic bacteria, releasing hydrogen gas.\nsynonyms :\n'}


{'id': 'HP_4000101', 'url': 'http://purl.obolibrary.org/obo/HP_4000101', 'lbl': 'Triggered by exposure to medication', 'desc': 'label: Triggered by exposure to medication\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to a medication.\nsynonyms :\n'}


{'id': 'HP_4000102', 'url': 'http://purl.obolibrary.org/obo/HP_4000102', 'lbl': 'Triggered by allopurinol', 'desc': 'label: Triggered by allopurinol\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to allopurinol.\nsynonyms :Allopurinol exposure\n'}


{'id': 'HP_4000103', 'url': 'http://purl.obolibrary.org/obo/HP_4000103', 'lbl': 'Ameliorated by oral zinc supplementation', 'desc': 'label: Ameliorated by oral zinc supplementation\ndefinition : Applies to a sign or symptom that is improved or made more bearable by oral zinc supplementation.\nsynonyms :Zinc oral supplementation produces improvement\n'}


{'id': 'HP_4000104', 'url': 'http://purl.obolibrary.org/obo/HP_4000104', 'lbl': 'Curved dental root', 'desc': 'label: Curved dental root\ndefinition : A root of a tooth that is more rounded than normal.\nsynonyms :Dental roots curved\n'}


{'id': 'HP_4000105', 'url': 'http://purl.obolibrary.org/obo/HP_4000105', 'lbl': 'Abnormal four chamber view of the fetal heart', 'desc': "label: Abnormal four chamber view of the fetal heart\ndefinition : The four-chamber (4Ch) view of the fetal heart is the most widely used screening examination for the detection of structural cardiac abnormalities during routine fetal ultrasonography. In the healthy normal fetus, the apical 4Ch view demonstrates four well-developed chambers, a concordant atrioventricular (AV) connection, unobstructed AV valves (mitral and tricuspid valves), the foramen ovale flap opening into left atrium (LA), and an intact interventricular septum. Additionally, the pulmonary venous opening can be visualized at the LA wall. Any structural deviations from normal anatomy may lead to congenital heart disease that can be determined by the 4Ch view of the fetal heart's ultrasound imaging.\nsynonyms :Abnormal four chamber view\n"}


{'id': 'HP_4000106', 'url': 'http://purl.obolibrary.org/obo/HP_4000106', 'lbl': 'Spleen hamartoma', 'desc': 'label: Spleen hamartoma\ndefinition : A hamartomatous lesion (benign focal lesions composed of disorganized tissue elements) localized in the spleen.\nsynonyms :\n'}


{'id': 'HP_4000107', 'url': 'http://purl.obolibrary.org/obo/HP_4000107', 'lbl': 'Positive lupus band test', 'desc': 'label: Positive lupus band test\ndefinition : Deposits of immunoglobulins and complement components along the dermoepidermal junction.\nsynonyms :Lupus band test positive\n'}


{'id': 'HP_4000108', 'url': 'http://purl.obolibrary.org/obo/HP_4000108', 'lbl': 'Bone marrow erythroid vacuolization', 'desc': 'label: Bone marrow erythroid vacuolization\ndefinition : Formation of vacuoles (a space within a cell that is empty of cytoplasm, lined with a membrane, and filled with fluid) in the cytoplasm of erythroid precursors in the bone marrow.\nsynonyms :Bone marrow: erythroid vacuolization\n'}


{'id': 'HP_4000109', 'url': 'http://purl.obolibrary.org/obo/HP_4000109', 'lbl': 'Triggered by electromagnetic field', 'desc': 'label: Triggered by electromagnetic field\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to an electromagnetic field.\nsynonyms :Electromagnetic field triggers symptoms\n'}


{'id': 'HP_4000110', 'url': 'http://purl.obolibrary.org/obo/HP_4000110', 'lbl': 'Exposure history', 'desc': 'label: Exposure history\ndefinition : Information about current and past exposure to metals, dust, fibers, fumes, chemicals, biologic hazards, radiation, noise, and/or vibration at work or home.\nsynonyms :\n'}


{'id': 'HP_4000111', 'url': 'http://purl.obolibrary.org/obo/HP_4000111', 'lbl': 'Asbestos exposure', 'desc': 'label: Asbestos exposure\ndefinition : History of exposure to asbestos, a fibrous mineral with physical and chemical properties that make it resistant to heat and degradation.\nsynonyms :\n'}


{'id': 'HP_4000112', 'url': 'http://purl.obolibrary.org/obo/HP_4000112', 'lbl': 'Medication history', 'desc': 'label: Medication history\ndefinition : Information about current or past medications taken by an individual.\nsynonyms :\n'}


{'id': 'HP_4000113', 'url': 'http://purl.obolibrary.org/obo/HP_4000113', 'lbl': 'Aminoglycoside exposure', 'desc': 'label: Aminoglycoside exposure\ndefinition : History of having taken aminoglycoside antibiotics.\nsynonyms :\n'}


{'id': 'HP_4000114', 'url': 'http://purl.obolibrary.org/obo/HP_4000114', 'lbl': 'Statin exposure', 'desc': 'label: Statin exposure\ndefinition : History of having taken statins, also known as HMG-CoA reductase inhibitors.\nsynonyms :\n'}


{'id': 'HP_4000115', 'url': 'http://purl.obolibrary.org/obo/HP_4000115', 'lbl': 'Potassium-sparing diuretic exposure', 'desc': 'label: Potassium-sparing diuretic exposure\ndefinition : History of having taken a potassium-sparing diuretic exposure such as amiloride, eplerenone, spironolactone, and triamterene.\nsynonyms :\n'}


{'id': 'HP_4000116', 'url': 'http://purl.obolibrary.org/obo/HP_4000116', 'lbl': 'Carbamazepine exposure', 'desc': 'label: Carbamazepine exposure\ndefinition : History of having taken carbamazepine.\nsynonyms :\n'}


{'id': 'HP_4000117', 'url': 'http://purl.obolibrary.org/obo/HP_4000117', 'lbl': 'Valproate exposure', 'desc': 'label: Valproate exposure\ndefinition : History of having taken valproate (valproic acid).\nsynonyms :\n'}


{'id': 'HP_4000118', 'url': 'http://purl.obolibrary.org/obo/HP_4000118', 'lbl': 'Hydralazine exposure', 'desc': 'label: Hydralazine exposure\ndefinition : History of having taken hydralazine.\nsynonyms :\n'}


{'id': 'HP_4000119', 'url': 'http://purl.obolibrary.org/obo/HP_4000119', 'lbl': 'Calcium channel blocker exposure', 'desc': 'label: Calcium channel blocker exposure\ndefinition : History of having taken a calcium channel blocker such as amlodipine, nicardipine, nifedipine, verapamil, or diltiazem.\nsynonyms :Calcium channel blocking drug use\n'}


{'id': 'HP_4000120', 'url': 'http://purl.obolibrary.org/obo/HP_4000120', 'lbl': 'Triggered by nickel', 'desc': 'label: Triggered by nickel\ndefinition : \nsynonyms :Contact with nickel\n'}


{'id': 'HP_4000121', 'url': 'http://purl.obolibrary.org/obo/HP_4000121', 'lbl': 'Triggered by poison ivy, poson oak, or sumac', 'desc': 'label: Triggered by poison ivy, poson oak, or sumac\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure (cutaneous contact) to poison ivy, poison oak, and poison sumac. These three plants each contain urushiol. Contact with these plants is the most common causes of clinically diagnosed allergic contact dermatitis.\nsynonyms :Contact with poison ivy, poison oak, or sumac\n'}


{'id': 'HP_4000122', 'url': 'http://purl.obolibrary.org/obo/HP_4000122', 'lbl': 'History of exclusive breast feeding', 'desc': 'label: History of exclusive breast feeding\ndefinition : A past medical history of having been fed exclusively by breast feeding.\nsynonyms :Breast feeding, exclusive\n'}


{'id': 'HP_4000123', 'url': 'http://purl.obolibrary.org/obo/HP_4000123', 'lbl': 'Nutrition history', 'desc': 'label: Nutrition history\ndefinition : A part of the past medical history consisting of information about the typical food intake of an individual.\nsynonyms :\n'}


{'id': 'HP_4000124', 'url': 'http://purl.obolibrary.org/obo/HP_4000124', 'lbl': 'High dietary oxalate intake', 'desc': 'label: High dietary oxalate intake\ndefinition : A history of ingestion of a relatively high amount of foods containing high levels of oxalate, such as green-leaf vegetables, tea, nuts, chocolate and rhubarb.\nsynonyms :Foods high in oxalate, high intake\n'}


{'id': 'HP_4000125', 'url': 'http://purl.obolibrary.org/obo/HP_4000125', 'lbl': 'Recent honey ingestion', 'desc': 'label: Recent honey ingestion\ndefinition : A history of ingestion of honey in recent weeks.\nsynonyms :Honey ingestion in recent weeks\n'}


{'id': 'HP_4000126', 'url': 'http://purl.obolibrary.org/obo/HP_4000126', 'lbl': 'Raw egg-white ingestion', 'desc': 'label: Raw egg-white ingestion\ndefinition : A history of eating raw egg whites.\nsynonyms :\n'}


{'id': 'HP_4000127', 'url': 'http://purl.obolibrary.org/obo/HP_4000127', 'lbl': 'Aggravated by sodium channel blocking agents', 'desc': 'label: Aggravated by sodium channel blocking agents\ndefinition : Applied to a sign or symptom that is worsened by administration of sodium channel blocking agents such as phenytoin, carbamazepine, oxcarbazepine, lamotrigine, topiramate, and zonisamide.\nsynonyms :Sodium channel blocking drugs aggravate findings\n'}


{'id': 'HP_4000128', 'url': 'http://purl.obolibrary.org/obo/HP_4000128', 'lbl': 'Nitric oxide addiction', 'desc': 'label: Nitric oxide addiction\ndefinition : Addiction to inhaled nitrous oxide gas (N2O).\nsynonyms :Nitrous oxide abuse\n'}


{'id': 'HP_4000129', 'url': 'http://purl.obolibrary.org/obo/HP_4000129', 'lbl': 'Recent blood transfusion', 'desc': 'label: Recent blood transfusion\ndefinition : A past medical history of a recent blood transfusion.\nsynonyms :Blood transfusion, recent\n'}


{'id': 'HP_4000130', 'url': 'http://purl.obolibrary.org/obo/HP_4000130', 'lbl': 'Ameliorated by colchicine', 'desc': 'label: Ameliorated by colchicine\ndefinition : Applies to a sign or symptom that is improved or made more bearable by administration of colchizine.\nsynonyms :Colchicine ameliorates symptoms\n'}


{'id': 'HP_4000131', 'url': 'http://purl.obolibrary.org/obo/HP_4000131', 'lbl': 'Ameliorated by vitamin D', 'desc': 'label: Ameliorated by vitamin D\ndefinition : Applies to a sign or symptom that is improved or made more bearable by administration of vitamin D.\nsynonyms :Vitamin D reduces manifestations\n'}


{'id': 'HP_4000132', 'url': 'http://purl.obolibrary.org/obo/HP_4000132', 'lbl': 'Aggravated by phenytoin', 'desc': 'label: Aggravated by phenytoin\ndefinition : Applied to a sign or symptom that is worsened by administration of phenytoin.\nsynonyms :Phenytoin produces worsening\n'}


{'id': 'HP_4000133', 'url': 'http://purl.obolibrary.org/obo/HP_4000133', 'lbl': 'Triggered by angiotensin-converting enzyme inhibitor', 'desc': 'label: Triggered by angiotensin-converting enzyme inhibitor\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to anngiotensin-converting enzyme inhibitor such as benazepril, captopril, enalapril, fosinopril, and lisinopril.\nsynonyms :ACE inhibitors trigger attacks\n'}


{'id': 'HP_4000134', 'url': 'http://purl.obolibrary.org/obo/HP_4000134', 'lbl': 'Prostaglandin E1 exposure', 'desc': 'label: Prostaglandin E1 exposure\ndefinition : History of having been treateed with prostaglandin E1.\nsynonyms :\n'}


{'id': 'HP_4000135', 'url': 'http://purl.obolibrary.org/obo/HP_4000135', 'lbl': '5-fluorouracil exposure', 'desc': 'label: 5-fluorouracil exposure\ndefinition : History of having been treated with 5-fluorouracil.\nsynonyms :\n'}


{'id': 'HP_4000136', 'url': 'http://purl.obolibrary.org/obo/HP_4000136', 'lbl': '6-mercaptopurine exposure', 'desc': 'label: 6-mercaptopurine exposure\ndefinition : History of having been treateed with 6-mercaptopurine.\nsynonyms :\n'}


{'id': 'HP_4000137', 'url': 'http://purl.obolibrary.org/obo/HP_4000137', 'lbl': 'Isoniazid exposure', 'desc': 'label: Isoniazid exposure\ndefinition : History of having been treateed with isoniazid.\nsynonyms :\n'}


{'id': 'HP_4000138', 'url': 'http://purl.obolibrary.org/obo/HP_4000138', 'lbl': 'Absent cavum septum pellucidum', 'desc': 'label: Absent cavum septum pellucidum\ndefinition : The cavum septum pellucidum (CSP) is an important fetal midline forebrain landmark that is normally visible by prenatal sonography. This term refers to the lack of visiblity of the CSP on prenatal sonography. The CSP normally can be visualized between 18 and 37 weeks of gestation. Lack of visualization of the CSP in this time period generally requires follow up and may indicate the presence of underlying malformations such as malformations of the corpus callosum. The lack of CSP before 18 weeks or after 37 weeks of gestation (or postnatally) is considered a normal finding.\nsynonyms :\n'}


{'id': 'HP_4000139', 'url': 'http://purl.obolibrary.org/obo/HP_4000139', 'lbl': 'Fetal abdominal cyst', 'desc': 'label: Fetal abdominal cyst\ndefinition : Fetal abdominal cysts are usually detected during the second trimester anomaly scan or discovered incidentally at later gestations. However, a definitive diagnosis is often not made until postnatal life. The most common etiologies of fetal abdominal cysts are: ovarian, gastrointestinal cystic duplication, liver and choledochal, meconium pseudocysts, mesenteric and adrenal. Following identification of a cyst, careful morphological assessment allows the prediction of their natural history and importantly, the likelihood of surgical intervention being required postnatally.\nsynonyms :Fetal cystic abdominal mass; Foetal abdominal cyst; Foetal cystic abdominal mass\n'}


{'id': 'HP_4000140', 'url': 'http://purl.obolibrary.org/obo/HP_4000140', 'lbl': 'Fetal bowel dilatation', 'desc': 'label: Fetal bowel dilatation\ndefinition : Fetal bowel dilatation is characterized by fluid-filled intestinal loops which measure at least fifteen millimeters long or seven millimeters in diameter. Ultrasonographic image of dilated fetal bowel is a sign of intestinal mechanical or functional obstruction and its prevalence will depend on the underlying condition: bowel atresia or stenosis, malrotation with volvulus, meconium ileus, total colonic aganglionosis, and meconium plug syndrome. The etiology of fetal bowel dilatation is a difficult prenatal diagnosis since ultrasound has limited accuracy for bowel evaluation.\nsynonyms :Foetal bowel dilatation\n'}


{'id': 'HP_4000141', 'url': 'http://purl.obolibrary.org/obo/HP_4000141', 'lbl': 'Left ventricular dilatation', 'desc': 'label: Left ventricular dilatation\ndefinition : Enlargement of the chamber of the left heart ventricle.\nsynonyms :Dilated left heart ventricle\n'}


{'id': 'HP_4000142', 'url': 'http://purl.obolibrary.org/obo/HP_4000142', 'lbl': 'Fetal trigonocephaly', 'desc': 'label: Fetal trigonocephaly\ndefinition : A fetal ultrasound finding defined by flattening of the occiput with pointing of the frontal bones and brachycephaly with an increased cephalic index. It is characterized by keel shaped deformity of forehead with midline ridge, bilateral fronto temporal constriction with compensatory biparietal expansion, supra orbital and lateral orbital retrusion and hypotelorism. This finding is said to resemble a strawberry.\nsynonyms :Foetal trigonocephaly; Strawberry sign; Strawberry skull; Strawberry-shaped skull\n'}


{'id': 'HP_4000143', 'url': 'http://purl.obolibrary.org/obo/HP_4000143', 'lbl': 'Abnormal fetal heart outflow tract', 'desc': 'label: Abnormal fetal heart outflow tract\ndefinition : A prenatal anomaly of the outflow tract. Fetal ultrasound may not always be able to easily and accurately describe the outflow anomaly, but can detect abnormal anatomy. Often, follow up with a fetal echo is recommended, but fetal ultrasound is limited.\nsynonyms :\n'}


{'id': 'HP_4000144', 'url': 'http://purl.obolibrary.org/obo/HP_4000144', 'lbl': 'Recent past medical history', 'desc': 'label: Recent past medical history\ndefinition : History of events that precede the current presenting condition and are thought to be of potential relevance, having occured in the hours, days, or weeks before the current condition.\nsynonyms :\n'}


{'id': 'HP_4000145', 'url': 'http://purl.obolibrary.org/obo/HP_4000145', 'lbl': 'History of recent viral illness', 'desc': 'label: History of recent viral illness\ndefinition : Medical history of a viral illness in recent weeks.\nsynonyms :Antecedent viral illness\n'}


{'id': 'HP_4000146', 'url': 'http://purl.obolibrary.org/obo/HP_4000146', 'lbl': 'History of recent dental procedure', 'desc': 'label: History of recent dental procedure\ndefinition : Medical history of a dental procedure in recent weeks.\nsynonyms :\n'}


{'id': 'HP_4000147', 'url': 'http://purl.obolibrary.org/obo/HP_4000147', 'lbl': 'Abnormal portal artery morphology', 'desc': 'label: Abnormal portal artery morphology\ndefinition : Any structural anomaly of the portal artery.\nsynonyms :\n'}


{'id': 'HP_4000148', 'url': 'http://purl.obolibrary.org/obo/HP_4000148', 'lbl': 'Portal artery hyperplasia', 'desc': 'label: Portal artery hyperplasia\ndefinition : Abnormal increase in size of the portal arteries of the liver.\nsynonyms :\n'}


{'id': 'HP_4000149', 'url': 'http://purl.obolibrary.org/obo/HP_4000149', 'lbl': 'Lymph node necrosis', 'desc': 'label: Lymph node necrosis\ndefinition : Areas of necrotic tissue within a lymph node.\nsynonyms :Necrosis in lymph node\n'}


{'id': 'HP_4000150', 'url': 'http://purl.obolibrary.org/obo/HP_4000150', 'lbl': 'Multinucleated neuron', 'desc': 'label: Multinucleated neuron\ndefinition : Neurons that contain more than one nucleus.\nsynonyms :\n'}


{'id': 'HP_4000151', 'url': 'http://purl.obolibrary.org/obo/HP_4000151', 'lbl': 'History of recent cotralateral injury', 'desc': 'label: History of recent cotralateral injury\ndefinition : A history of an injury that occurred several hours, days, or weeks before the current presenting complaint and is located on the other side of the body relative to the current presenting complaint.\nsynonyms :\n'}


{'id': 'HP_4000152', 'url': 'http://purl.obolibrary.org/obo/HP_4000152', 'lbl': 'Alternating laterality', 'desc': 'label: Alternating laterality\ndefinition : Occuring on the left and right in succession. This term can refer to alternating sides of the body (e.g., Alternating hemiplegia) or alternative sides of the visual field (e.g., some migraine auras).\nsynonyms :Alternating sides of the body\n'}


{'id': 'HP_4000153', 'url': 'http://purl.obolibrary.org/obo/HP_4000153', 'lbl': 'Cervical squamous cell papilloma', 'desc': 'label: Cervical squamous cell papilloma\ndefinition : A benign tumor arising from the epithelial surface of the cervix and usually caused by Human Papillomavirus infection.\nsynonyms :Cervix squamous papilloma\n'}


{'id': 'HP_4000154', 'url': 'http://purl.obolibrary.org/obo/HP_4000154', 'lbl': 'Liver leiomyoma', 'desc': 'label: Liver leiomyoma\ndefinition : A benign smooth muscle neoplasm that arises in the liver.\nsynonyms :Hepatic leiomyoma\n'}


{'id': 'HP_4000158', 'url': 'http://purl.obolibrary.org/obo/HP_4000158', 'lbl': 'Typified by high penetrance', 'desc': 'label: Typified by high penetrance\ndefinition : Description of conditions in which only an incomplete but relatively high proportion of individuals with a given genotype exhibit the disease regardless of age assuming a full lifespan of 80 years. There is no commonly accepted definition for incomplete, but high penetrance, but we suggest that this term be applied if at least 80 percent but less than 100 percent of individuals with the given genotype would manifest the disease with a full lifespan.\nsynonyms :\n'}


{'id': 'HP_4000159', 'url': 'http://purl.obolibrary.org/obo/HP_4000159', 'lbl': 'Typified by moderate penetrance', 'desc': 'label: Typified by moderate penetrance\ndefinition : Description of conditions in which only a moderate proportion of individuals with a given genotype exhibit the disease regardless of age assuming a full lifespan of 80 years. There is no commonly accepted definition for moderate penetrance, but we suggest that this term be applied if at least 20 percent but less than 80 percent of individuals with the given genotype would manifest the disease with a full lifespan.\nsynonyms :\n'}


{'id': 'HP_4000160', 'url': 'http://purl.obolibrary.org/obo/HP_4000160', 'lbl': 'Typified by low penetrance', 'desc': 'label: Typified by low penetrance\ndefinition : Description of conditions in which only a low proportion of individuals with a given genotype exhibit the disease regardless of age assuming a full lifespan of 80 years. There is no commonly accepted definition for low penetrance, but we suggest that this term be applied if at least some but less than 20 percent of carriers would manifest the disease with a full lifespan.\nsynonyms :\n'}


{'id': 'HP_4000162', 'url': 'http://purl.obolibrary.org/obo/HP_4000162', 'lbl': 'Decreased Succinyl-CoA 3-ketoacid CoA transferase activity', 'desc': 'label: Decreased Succinyl-CoA 3-ketoacid CoA transferase activity\ndefinition : Decreased activity of the enzyme succinyl-CoA 3-ketoacid CoA transferase.\nsynonyms :SCOT activity low in fibroblasts\n'}


{'id': 'HP_4000163', 'url': 'http://purl.obolibrary.org/obo/HP_4000163', 'lbl': 'Decreased phytanoyl-CoA hydroxylase activity', 'desc': 'label: Decreased phytanoyl-CoA hydroxylase activity\ndefinition : Reduced activity of the enzyme phytanoyl-CoA hydroxylase, which plays a role in the catabolism of phytanic acid, a branched-chain fatty acid that is a normal constituent of the human diet.\nsynonyms :PhyH activity low in fibroblasts\n'}


{'id': 'HP_4000164', 'url': 'http://purl.obolibrary.org/obo/HP_4000164', 'lbl': 'Reduced bifunctional protein activity', 'desc': 'label: Reduced bifunctional protein activity\ndefinition : Diminished activity of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), also known as D-bifunctional protein (DBP), a peroxisomal enzyme that catalyzes multiple steps of beta-oxidation of very long chain fatty acids.\nsynonyms :Reduced 17-beta-hydroxysteroid dehydrogenase 4 activity\n'}


{'id': 'HP_4000165', 'url': 'http://purl.obolibrary.org/obo/HP_4000165', 'lbl': 'Decreased circulating plasmalogen concentration', 'desc': 'label: Decreased circulating plasmalogen concentration\ndefinition : Reduced plasmalogen concentration in the blood circulation.\nsynonyms :Reduced circulating plasmalogen concentration\n'}


{'id': 'HP_4000166', 'url': 'http://purl.obolibrary.org/obo/HP_4000166', 'lbl': 'Post-vaccination varicella zoster virus infection', 'desc': 'label: Post-vaccination varicella zoster virus infection\ndefinition : Infection with live, attenuated varicella-zoster virus following vaccination. This is an extreemely rare event that may indicate immunocompromise.\nsynonyms :Varicella zoster virus infection after vaccination\n'}


{'id': 'HP_4000167', 'url': 'http://purl.obolibrary.org/obo/HP_4000167', 'lbl': 'Recent steroid exposure', 'desc': 'label: Recent steroid exposure\ndefinition : History of having been treated with corticosteroid medications in recent weeks.\nsynonyms :History of recent steroid use\n'}


{'id': 'HP_4000168', 'url': 'http://purl.obolibrary.org/obo/HP_4000168', 'lbl': 'Shark teeth', 'desc': 'label: Shark teeth\ndefinition : Eruption of permanent teeth behind deciduous (baby) teeth before they have fallen out, resulting in a double row of teeth. This phenomen is typically observed between the ages of 5 to 7 years.\nsynonyms :Cauliflower teeth; Double-parked teeth; Teeth: double row\n'}


{'id': 'HP_4000169', 'url': 'http://purl.obolibrary.org/obo/HP_4000169', 'lbl': 'Pontine T2 hypointensity', 'desc': 'label: Pontine T2 hypointensity\ndefinition : A darker than expected T2 signal on magnetic resonance imaging (MRI) of the pons.\nsynonyms :\n'}


{'id': 'HP_4000170', 'url': 'http://purl.obolibrary.org/obo/HP_4000170', 'lbl': 'Anti-platelet antigen antibody positivity', 'desc': 'label: Anti-platelet antigen antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against antigens present on the surface of thrombocytes such as the glycoproteins GPIIb/IIIa, GPIb/IX, and GPIa/IIa.\nsynonyms :Antiplatelet antibodies present\n'}


{'id': 'HP_4000171', 'url': 'http://purl.obolibrary.org/obo/HP_4000171', 'lbl': 'Anti-voltage-gated potassium channel antibody positivity', 'desc': 'label: Anti-voltage-gated potassium channel antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against a voltage-gated potassium channel.\nsynonyms :Voltage gated potassium channel antibodies in blood\n'}


{'id': 'HP_4000172', 'url': 'http://purl.obolibrary.org/obo/HP_4000172', 'lbl': 'Vegan diet', 'desc': 'label: Vegan diet\ndefinition : A history of following a vegan diet characterized by avoidance of food sourced from animals including meet, fish, and dairy products.\nsynonyms :\n'}


{'id': 'HP_4000173', 'url': 'http://purl.obolibrary.org/obo/HP_4000173', 'lbl': 'History of previous pregnancy with hydrops fetalis', 'desc': 'label: History of previous pregnancy with hydrops fetalis\ndefinition : One or more previous pregnancies in which the fetus developed hydrops fetalis.\nsynonyms :History of hydrops fetalis in newborn offspring\n'}


{'id': 'HP_4000174', 'url': 'http://purl.obolibrary.org/obo/HP_4000174', 'lbl': 'Ameliorated by potassium supplements', 'desc': 'label: Ameliorated by potassium supplements\ndefinition : Applies to a sign or symptom that is improved or made more bearable by ingesting a potassium supplement.\nsynonyms :Potassium supplements alleviate attacks\n'}


{'id': 'HP_4000175', 'url': 'http://purl.obolibrary.org/obo/HP_4000175', 'lbl': 'Ameliorated by niacin', 'desc': 'label: Ameliorated by niacin\ndefinition : Applies to a sign or symptom that is improved or made more bearable by ingesting niacin (vitamin B3).\nsynonyms :Ameliorated by vitamin B3; Niacin reverses symptoms\n'}


{'id': 'HP_4000176', 'url': 'http://purl.obolibrary.org/obo/HP_4000176', 'lbl': 'Aggravated by exposure to medication', 'desc': 'label: Aggravated by exposure to medication\ndefinition : Applied to a sign or symptom that is worsened by treatment with a medication.\nsynonyms :\n'}


{'id': 'HP_4000177', 'url': 'http://purl.obolibrary.org/obo/HP_4000177', 'lbl': 'Bleeding ameliorated by vitamin K', 'desc': 'label: Bleeding ameliorated by vitamin K\ndefinition : Applies to bleeding that is significantly reduced by treatment with vitamin K.\nsynonyms :Vitamin K treatment reduces bleeding significantly\n'}


{'id': 'HP_4000178', 'url': 'http://purl.obolibrary.org/obo/HP_4000178', 'lbl': 'Anti-retroviral therapy exposure', 'desc': 'label: Anti-retroviral therapy exposure\ndefinition : History of having been treated with an antiretroviral agent.\nsynonyms :\n'}


{'id': 'HP_4000179', 'url': 'http://purl.obolibrary.org/obo/HP_4000179', 'lbl': 'Potassium-wasting diuretic exposure', 'desc': 'label: Potassium-wasting diuretic exposure\ndefinition : History of having been treated with a potassium-wasting diuretic such as thiazide (chlorothiazide, chlorthalidone, hydrochlorothiazide, indapamide, metolazone) and loop (bumetanide, ethacrynic acid, furosemide, torsemide) diuretics.\nsynonyms :\n'}


{'id': 'HP_4000180', 'url': 'http://purl.obolibrary.org/obo/HP_4000180', 'lbl': 'Tricyclic antidepressant exposure', 'desc': 'label: Tricyclic antidepressant exposure\ndefinition : History of having been treated with a tricyclic antidepressant medication.\nsynonyms :Tricyclic antidepressant use\n'}


{'id': 'HP_4000181', 'url': 'http://purl.obolibrary.org/obo/HP_4000181', 'lbl': 'Excessive dental attrition', 'desc': 'label: Excessive dental attrition\ndefinition : A higher than expected amount of attrition of teeth, as menifested by loss of tooth characteristics including rounding or sharpening of incisal edges, loss of cusps, and fracturing of teeth, to an extent that is deemed more than would be expected at a given age.\nsynonyms :Excessive tooth attrition; Excessive wear and tear on teeth\n'}


{'id': 'HP_4000182', 'url': 'http://purl.obolibrary.org/obo/HP_4000182', 'lbl': 'Positionally dependent pain', 'desc': 'label: Positionally dependent pain\ndefinition : Pain improves or worsens with changes in body position.\nsynonyms :Positional nature to pain\n'}


{'id': 'HP_4000183', 'url': 'http://purl.obolibrary.org/obo/HP_4000183', 'lbl': 'Abnormal erythrocyte adenosine triphosphate concentration', 'desc': 'label: Abnormal erythrocyte adenosine triphosphate concentration\ndefinition : Concentration of adenosine triphosphate (ATP) in red blood cells (erythrocytes) outside of the normal range.\nsynonyms :\n'}


{'id': 'HP_4000184', 'url': 'http://purl.obolibrary.org/obo/HP_4000184', 'lbl': 'Reduced erythrocyte adenosine triphosphate concentration', 'desc': 'label: Reduced erythrocyte adenosine triphosphate concentration\ndefinition : Concentration of adenosine triphosphate (ATP) in red blood cells (erythrocytes) below the lower limit of normal.\nsynonyms :\n'}


{'id': 'HP_4000186', 'url': 'http://purl.obolibrary.org/obo/HP_4000186', 'lbl': 'Elevated erythrocyte adenosine triphosphate concentration', 'desc': 'label: Elevated erythrocyte adenosine triphosphate concentration\ndefinition : Concentration of adenosine triphosphate (ATP) in red blood cells (erythrocytes) above the upper limit of normal.\nsynonyms :Adenosine triphosphate (ATP) high in erythrocytes\n'}


{'id': 'HP_5000000', 'url': 'http://purl.obolibrary.org/obo/HP_5000000', 'lbl': 'Anti-AK5 antibody positivity', 'desc': 'label: Anti-AK5 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against anti-adenylate kinase 5 (AK5).\nsynonyms :\n'}


{'id': 'HP_5000001', 'url': 'http://purl.obolibrary.org/obo/HP_5000001', 'lbl': 'Anti-AMPAR antibody positivity', 'desc': 'label: Anti-AMPAR antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR).\nsynonyms :Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antibody\n'}


{'id': 'HP_5000002', 'url': 'http://purl.obolibrary.org/obo/HP_5000002', 'lbl': 'Anti-Amphiphysin antibody', 'desc': 'label: Anti-Amphiphysin antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Amphiphysin.\nsynonyms :\n'}


{'id': 'HP_5000003', 'url': 'http://purl.obolibrary.org/obo/HP_5000003', 'lbl': 'Anti-ARHGAP26 antibody', 'desc': 'label: Anti-ARHGAP26 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Rho GTPase-activating protein 26 (ARHGAP26).\nsynonyms :Anti-Ca antibody; Anti-RhoGTPase-activating protein 26 antibody\n'}


{'id': 'HP_5000004', 'url': 'http://purl.obolibrary.org/obo/HP_5000004', 'lbl': 'Anti-CARP VIII antibody', 'desc': 'label: Anti-CARP VIII antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Carbonic anhydrase-related protein VIII (CARPVIII).\nsynonyms :Anti CARPVIII antibody; Anti-carbonic anhydrase-related protein VIII antibody\n'}


{'id': 'HP_5000005', 'url': 'http://purl.obolibrary.org/obo/HP_5000005', 'lbl': 'Anti-CASPR2', 'desc': 'label: Anti-CASPR2\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against contactin-associated protein-like 2 (CASPR2).\nsynonyms :Anti-Caspr2 antibody; Anti-contactin-associated protein-like 2 antibody\n'}


{'id': 'HP_5000006', 'url': 'http://purl.obolibrary.org/obo/HP_5000006', 'lbl': 'Anti-CV2/CRMP5 antibody positivity', 'desc': 'label: Anti-CV2/CRMP5 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against CV2/CRMP5. Anti-CV2/CRMP5 autoantibody is the most commonly detected anti-neuronal autoantibody. Patients with typical paraneoplastic chorea show fully developed chorea in the course of weeks to months with acute inflammation in the striatum.\nsynonyms :Anti-CV2 antibody; Anti-CV2/collapsin response mediator protein (CRMP)5 antibody; Anti-collapsin response-mediated protein 5 antibody\n'}


{'id': 'HP_5000007', 'url': 'http://purl.obolibrary.org/obo/HP_5000007', 'lbl': 'Anti-DPPX antibody', 'desc': 'label: Anti-DPPX antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against dipeptidyl-peptidase-like protein 6 (DPPX).\nsynonyms :Anti-dipeptidyl-peptidase-like protein 6 antibody\n'}


{'id': 'HP_5000008', 'url': 'http://purl.obolibrary.org/obo/HP_5000008', 'lbl': 'Anti-FGFR3 antibody positivity', 'desc': 'label: Anti-FGFR3 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against FGFR3.\nsynonyms :Anti-fibroblast growth factor receptor 3 antibody\n'}


{'id': 'HP_5000009', 'url': 'http://purl.obolibrary.org/obo/HP_5000009', 'lbl': 'Anti-GABA(A)R antibody', 'desc': 'label: Anti-GABA(A)R antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against gamma-aminobutyric acid A receptor, i.e., GABA(A)R.\nsynonyms :Anti-GABAA R antibody; Anti-gamma amino butyric acid type A receptors antibody\n'}


{'id': 'HP_5000010', 'url': 'http://purl.obolibrary.org/obo/HP_5000010', 'lbl': 'Anti-GABA(B)R antibody', 'desc': 'label: Anti-GABA(B)R antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against gamma-aminobutyric acid B receptor, i.e., GABA(B)R.\nsynonyms :Anti-gamma-aminobutyric acid B receptor antibody\n'}


{'id': 'HP_5000011', 'url': 'http://purl.obolibrary.org/obo/HP_5000011', 'lbl': 'Anti-GAD65 antibody', 'desc': 'label: Anti-GAD65 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against glutamic acid decarboxylase 65 (GAD65).\nsynonyms :Anti-glutamic acid decarboxylase 65 antibody\n'}


{'id': 'HP_5000012', 'url': 'http://purl.obolibrary.org/obo/HP_5000012', 'lbl': 'Anti-Gephyrin antibody', 'desc': 'label: Anti-Gephyrin antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Gephyrin.\nsynonyms :\n'}


{'id': 'HP_5000013', 'url': 'http://purl.obolibrary.org/obo/HP_5000013', 'lbl': 'Anti-GFAP antibody', 'desc': 'label: Anti-GFAP antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against glial fibrillary acidic protein (GFAP).\nsynonyms :Anti-glial fibrillary acidic protein antibody\n'}


{'id': 'HP_5000014', 'url': 'http://purl.obolibrary.org/obo/HP_5000014', 'lbl': 'Anti-GlyR antibody', 'desc': 'label: Anti-GlyR antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Glycine receptor (GlyR).\nsynonyms :Anti-glycine receptor antibody\n'}


{'id': 'HP_5000015', 'url': 'http://purl.obolibrary.org/obo/HP_5000015', 'lbl': 'Anti-Homer-3 antibody', 'desc': 'label: Anti-Homer-3 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Homer-3.\nsynonyms :Anti-Homer protein homolog 3 antibody\n'}


{'id': 'HP_5000016', 'url': 'http://purl.obolibrary.org/obo/HP_5000016', 'lbl': 'Anti-Hu antibody positivity', 'desc': 'label: Anti-Hu antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Hu.\nsynonyms :Anti-ANNA-1 antibody; Anti-Neuronal Nuclear Antibody type-1 antibody\n'}


{'id': 'HP_5000017', 'url': 'http://purl.obolibrary.org/obo/HP_5000017', 'lbl': 'Anti-Iglon5 antibody', 'desc': 'label: Anti-Iglon5 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against immunoglobulin-like cell adhesion molecule 5 (IgLON5).\nsynonyms :Anti-immunoglobulin-like cell adhesion molecule 5 antibody\n'}


{'id': 'HP_5000018', 'url': 'http://purl.obolibrary.org/obo/HP_5000018', 'lbl': 'Anti-ITPR1 antibody', 'desc': 'label: Anti-ITPR1 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against inositol 1,4,5-trisphosphate receptor 1 (ITPR1).\nsynonyms :Anti-inositol 1,4,5-trisphosphate receptor type 1 antibody\n'}


{'id': 'HP_5000019', 'url': 'http://purl.obolibrary.org/obo/HP_5000019', 'lbl': 'Anti-Kelch like protein 11 antibody positivity', 'desc': 'label: Anti-Kelch like protein 11 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against kelch-like protein 11 (KLHL11).\nsynonyms :Anti-KLHL11 antibody\n'}


{'id': 'HP_5000020', 'url': 'http://purl.obolibrary.org/obo/HP_5000020', 'lbl': 'Anti-LGI1 antibody', 'desc': 'label: Anti-LGI1 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against leucine-rich glioma-inactivated 1 (LGI1).\nsynonyms :Anti-Anti-leucine-rich glioma-inactivated 1 antibody\n'}


{'id': 'HP_5000021', 'url': 'http://purl.obolibrary.org/obo/HP_5000021', 'lbl': 'Anti-Ma antibody positivity', 'desc': 'label: Anti-Ma antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ma.\nsynonyms :\n'}


{'id': 'HP_5000022', 'url': 'http://purl.obolibrary.org/obo/HP_5000022', 'lbl': 'Anti-Ma2 antibody positivity', 'desc': 'label: Anti-Ma2 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ma2.\nsynonyms :Anti-Ta antibody\n'}


{'id': 'HP_5000023', 'url': 'http://purl.obolibrary.org/obo/HP_5000023', 'lbl': 'Anti-Ma1 antibody positivity', 'desc': 'label: Anti-Ma1 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ma1.\nsynonyms :\n'}


{'id': 'HP_5000024', 'url': 'http://purl.obolibrary.org/obo/HP_5000024', 'lbl': 'Anti-mGluR1 antibody', 'desc': 'label: Anti-mGluR1 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against metabotropic glutamate receptor 1 (mGluR1).\nsynonyms :Anti-metabotropic glutamate receptor 1 antibody\n'}


{'id': 'HP_5000025', 'url': 'http://purl.obolibrary.org/obo/HP_5000025', 'lbl': 'Anti-mGluR5 antibody', 'desc': 'label: Anti-mGluR5 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against metabotropic glutamate receptor 5 (mGluR5).\nsynonyms :Anti-Metabotropic Glutamate Receptor Type 5 antibody\n'}


{'id': 'HP_5000026', 'url': 'http://purl.obolibrary.org/obo/HP_5000026', 'lbl': 'Anti-neurexin-3alpha antibody positivity', 'desc': 'label: Anti-neurexin-3alpha antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against neurexin-3alpha.\nsynonyms :Anti-neurexin-3alpha antibody\n'}


{'id': 'HP_5000027', 'url': 'http://purl.obolibrary.org/obo/HP_5000027', 'lbl': 'Anti-P/Q-type VGCC antibody positivity', 'desc': 'label: Anti-P/Q-type VGCC antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against P/Q-type voltage-gated calcium channels (VGCCs).\nsynonyms :Anti-P/Q-type voltage-gated calcium-channel antibody\n'}


{'id': 'HP_5000028', 'url': 'http://purl.obolibrary.org/obo/HP_5000028', 'lbl': 'Anti-MAP1B antibody', 'desc': 'label: Anti-MAP1B antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against microtubule-associated protein 1B (MAP1B).\nsynonyms :Anti-Purkinje cell cytoplasmic type-2 antibody; Anti-microtubule-associated protein 1B antibody\n'}


{'id': 'HP_5000029', 'url': 'http://purl.obolibrary.org/obo/HP_5000029', 'lbl': 'Anti-PKCgamma antibody', 'desc': 'label: Anti-PKCgamma antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against protein kinase Cgamma.\nsynonyms :Anti-Protein kinase C gamma antibody\n'}


{'id': 'HP_5000030', 'url': 'http://purl.obolibrary.org/obo/HP_5000030', 'lbl': 'Anti-Ri antibody', 'desc': 'label: Anti-Ri antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ri, an antineuronal antibody.\nsynonyms :Anti-ANNA-2 antibody\n'}


{'id': 'HP_5000031', 'url': 'http://purl.obolibrary.org/obo/HP_5000031', 'lbl': 'Anti-Septin-5 antibody', 'desc': 'label: Anti-Septin-5 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Septin-5.\nsynonyms :\n'}


{'id': 'HP_5000032', 'url': 'http://purl.obolibrary.org/obo/HP_5000032', 'lbl': 'Anti-SEZ6L2 antibody', 'desc': 'label: Anti-SEZ6L2 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against seizure-related 6 homolog like 2 (SEZ6L2).\nsynonyms :\n'}


{'id': 'HP_5000033', 'url': 'http://purl.obolibrary.org/obo/HP_5000033', 'lbl': 'Anti-SOX1 antibody', 'desc': 'label: Anti-SOX1 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against SOX1. Anti-SOX1 antibodies, also known as antiglial nuclear antibody (AGNA), are specifically found in paraneoplastic neurological disorders. Since SOX1 is expressed in neuronal precursor cells in the developing central nervous system, it has been used as an early marker of neural stem cells.\nsynonyms :Anti-Sry-like high mobility group box (SOX) 1 antibody\n'}


{'id': 'HP_5000034', 'url': 'http://purl.obolibrary.org/obo/HP_5000034', 'lbl': 'Anti-Tr/DNER antibody', 'desc': 'label: Anti-Tr/DNER antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Tr/DNER. Anti-Tr antibodies are directed against cerebellar Purkinje cells (termed anti-Tr or PCA-Tr). Anti-Tr autoantibodies are frequently associated with Hodgkin lymphoma (HL). Anti-Tr antibodies are defined by a specific staining pattern in cerebellar tissue that is characterized by punctate immunoreactivity in both the dendritic tree and soma of Purkinje cells but not in their axons. This characteristic pattern is indicative of the presence of anti-Tr antibodies. The Delta/Notch-like epidermal growth factor-related receptor (DNER) was identified as the target antigen of anti-Tr.\nsynonyms :Anti-delta/notch-like epidermal growth factor-related receptor antibody; PCA-Tr\n'}


{'id': 'HP_5000035', 'url': 'http://purl.obolibrary.org/obo/HP_5000035', 'lbl': 'Anti-TRIM46 antibody', 'desc': 'label: Anti-TRIM46 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against the axon initial segment protein tripartite motif 46 (TRIM46).\nsynonyms :\n'}


{'id': 'HP_5000036', 'url': 'http://purl.obolibrary.org/obo/HP_5000036', 'lbl': 'Anti-TRIM9/TRIM67 antibody', 'desc': 'label: Anti-TRIM9/TRIM67 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against TRIM9/TRIM67.\nsynonyms :\n'}


{'id': 'HP_5000037', 'url': 'http://purl.obolibrary.org/obo/HP_5000037', 'lbl': 'Anti-Yo antibody positivity', 'desc': 'label: Anti-Yo antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Yo.\nsynonyms :Anti-Purkinje cell cytoplasmic antibody 1\n'}


{'id': 'HP_5000038', 'url': 'http://purl.obolibrary.org/obo/HP_5000038', 'lbl': 'Anti-titin antibody positivity', 'desc': 'label: Anti-titin antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against titin.\nsynonyms :\n'}


{'id': 'HP_5000039', 'url': 'http://purl.obolibrary.org/obo/HP_5000039', 'lbl': 'Anti-Zic4 antibody positivity', 'desc': 'label: Anti-Zic4 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Zic family member 4 (ZIC4).\nsynonyms :\n'}


{'id': 'HP_5000041', 'url': 'http://purl.obolibrary.org/obo/HP_5000041', 'lbl': 'obsolete Anti-CRMP5 antibody positivity', 'desc': 'label: obsolete Anti-CRMP5 antibody positivity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_5000042', 'url': 'http://purl.obolibrary.org/obo/HP_5000042', 'lbl': 'Anti-Sj/ITPR1 antibody', 'desc': 'label: Anti-Sj/ITPR1 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Sj/inositol 1,4,5-trisphosphate receptor.\nsynonyms :Anti-Sj/inositol 1,4,5-trisphosphate receptor antibody\n'}


{'id': 'HP_5000043', 'url': 'http://purl.obolibrary.org/obo/HP_5000043', 'lbl': 'Anti-D2 R antibody', 'desc': 'label: Anti-D2 R antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against dopamine-2 receptor.\nsynonyms :Anti-dopamine-2 receptors (D2R) antibody\n'}


{'id': 'HP_5000044', 'url': 'http://purl.obolibrary.org/obo/HP_5000044', 'lbl': 'Anti-GluK2 antibody', 'desc': 'label: Anti-GluK2 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against glutamate kainate receptor subunit 2 (GluK2).\nsynonyms :Anti-glutamate kainate receptor subunit 2 antibody\n'}


{'id': 'HP_5000045', 'url': 'http://purl.obolibrary.org/obo/HP_5000045', 'lbl': 'obsolete Anti-MuSK antibody positivity', 'desc': 'label: obsolete Anti-MuSK antibody positivity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_5000046', 'url': 'http://purl.obolibrary.org/obo/HP_5000046', 'lbl': 'Anti-Lrp4 antibody positivity', 'desc': 'label: Anti-Lrp4 antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against low-density lipoprotein receptor (Lrp4).\nsynonyms :Anti-low-density lipoprotein receptor-related protein 4 antibody\n'}


{'id': 'HP_5000047', 'url': 'http://purl.obolibrary.org/obo/HP_5000047', 'lbl': 'Anti-ryanodine receptor antibody', 'desc': 'label: Anti-ryanodine receptor antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against ryanodine receptor.\nsynonyms :Anti-RyR antibody\n'}


{'id': 'HP_5000048', 'url': 'http://purl.obolibrary.org/obo/HP_5000048', 'lbl': 'Anti-Kv1.4 antibody', 'desc': 'label: Anti-Kv1.4 antibody\ndefinition : The presence of autoantibodies (immunoglobulins) in the blood circulation that react against the voltage-gated potassium channel Kv1.4.\nsynonyms :\n'}


{'id': 'HP_5200001', 'url': 'http://purl.obolibrary.org/obo/HP_5200001', 'lbl': 'Selective mutism', 'desc': 'label: Selective mutism\ndefinition : Voluntary failure to use spoken language (at whatever level attained) in selective social contexts over a period of time.\nsynonyms :\n'}


{'id': 'HP_5200002', 'url': 'http://purl.obolibrary.org/obo/HP_5200002', 'lbl': 'Limited repertoire of facial expression', 'desc': "label: Limited repertoire of facial expression\ndefinition : An abnormally limited range of facial expressions demonstrated by a lack of nuance of facial expression to match specific social situations or an inability to demonstrate a normal range of emotions with one's face.\nsynonyms :Reduced range of facial expressions\n"}


{'id': 'HP_5200003', 'url': 'http://purl.obolibrary.org/obo/HP_5200003', 'lbl': 'Excessive interest in others', 'desc': 'label: Excessive interest in others\ndefinition : An unusually strong interest in others in general or tendency to develop a strong interest in certain individuals.\nsynonyms :\n'}


{'id': 'HP_5200004', 'url': 'http://purl.obolibrary.org/obo/HP_5200004', 'lbl': 'Reduced interest in others', 'desc': 'label: Reduced interest in others\ndefinition : A reduced interest in all people including both peers and non-peers.\nsynonyms :\n'}


{'id': 'HP_5200005', 'url': 'http://purl.obolibrary.org/obo/HP_5200005', 'lbl': 'Abnormal pitch', 'desc': 'label: Abnormal pitch\ndefinition : Abnormally high or low-pitched vocalization or speech.\nsynonyms :\n'}


{'id': 'HP_5200006', 'url': 'http://purl.obolibrary.org/obo/HP_5200006', 'lbl': 'Loose association', 'desc': 'label: Loose association\ndefinition : Speech characterized by weak (e.g. tangential/circumstantial) or absent (e.g. word salad) connections between ideas.\nsynonyms :\n'}


{'id': 'HP_5200007', 'url': 'http://purl.obolibrary.org/obo/HP_5200007', 'lbl': 'Neologism', 'desc': 'label: Neologism\ndefinition : Consistent use of an invented term, word, or phrase that is idiosyncratic to the individual.\nsynonyms :\n'}


{'id': 'HP_5200008', 'url': 'http://purl.obolibrary.org/obo/HP_5200008', 'lbl': 'Overly formal/pedantic language', 'desc': 'label: Overly formal/pedantic language\ndefinition : Use of language that is overly formal, precise, detailed, or pedantic for the social context.\nsynonyms :\n'}


{'id': 'HP_5200009', 'url': 'http://purl.obolibrary.org/obo/HP_5200009', 'lbl': 'Midline hand movements', 'desc': 'label: Midline hand movements\ndefinition : Hand stereotypies within the medial plane of the body.\nsynonyms :\n'}


{'id': 'HP_5200010', 'url': 'http://purl.obolibrary.org/obo/HP_5200010', 'lbl': 'Abnormal Intonation', 'desc': 'label: Abnormal Intonation\ndefinition : Abnormal rise and fall of the voice in speech and vocalization.\nsynonyms :\n'}


{'id': 'HP_5200011', 'url': 'http://purl.obolibrary.org/obo/HP_5200011', 'lbl': 'Abnormal speech rate', 'desc': 'label: Abnormal speech rate\ndefinition : Speech that is abnormally fast or slow\nsynonyms :\n'}


{'id': 'HP_5200012', 'url': 'http://purl.obolibrary.org/obo/HP_5200012', 'lbl': 'Abnormal speech rhythm', 'desc': 'label: Abnormal speech rhythm\ndefinition : Speech with abnormal rhythm or pattern\nsynonyms :\n'}


{'id': 'HP_5200013', 'url': 'http://purl.obolibrary.org/obo/HP_5200013', 'lbl': 'Ambiguous facial expression', 'desc': 'label: Ambiguous facial expression\ndefinition : Spontaneous production of communicative facial expressions that have poor quality or are perceived as odd or mechanical. This may include inaccurate mimicry of typical facial expressions. These expressions may be difficult to interpret for someone who is not familiar with the individual making the expression.\nsynonyms :\n'}


{'id': 'HP_5200014', 'url': 'http://purl.obolibrary.org/obo/HP_5200014', 'lbl': 'Exaggerated facial expression', 'desc': 'label: Exaggerated facial expression\ndefinition : A tendency to make facial expressions that are exaggerated and a failure to make subtle facial expressions in a social context when a subtle expression is more appropriate.\nsynonyms :\n'}


{'id': 'HP_5200015', 'url': 'http://purl.obolibrary.org/obo/HP_5200015', 'lbl': 'Muted facial expression', 'desc': 'label: Muted facial expression\ndefinition : A tendency to produce facial expressions with decreased intensity or expressivity which appear muted or flat.\nsynonyms :Flat facial expression\n'}


{'id': 'HP_5200016', 'url': 'http://purl.obolibrary.org/obo/HP_5200016', 'lbl': 'Abnormal peer relationships', 'desc': "label: Abnormal peer relationships\ndefinition : The state of having abnormal relationships with others. This does not describe specific aspects of one's social aptitudes but rather a state which may come about from these aptitudes, such as lacking peer relationships or lacking close friends.\nsynonyms :\n"}


{'id': 'HP_5200017', 'url': 'http://purl.obolibrary.org/obo/HP_5200017', 'lbl': 'Abnormal movements of face and head', 'desc': 'label: Abnormal movements of face and head\ndefinition : Abnormal movements of face and head.\nsynonyms :\n'}


{'id': 'HP_5200018', 'url': 'http://purl.obolibrary.org/obo/HP_5200018', 'lbl': 'Abnormal movements of the upper extremities', 'desc': 'label: Abnormal movements of the upper extremities\ndefinition : Abnormal movements of the upper extremities.\nsynonyms :\n'}


{'id': 'HP_5200019', 'url': 'http://purl.obolibrary.org/obo/HP_5200019', 'lbl': 'Abnormal movements of the whole body', 'desc': 'label: Abnormal movements of the whole body\ndefinition : Abnormal movements of the whole body.\nsynonyms :\n'}


{'id': 'HP_5200020', 'url': 'http://purl.obolibrary.org/obo/HP_5200020', 'lbl': 'Abnormal interest in others', 'desc': 'label: Abnormal interest in others\ndefinition : A social interest in others that is abnormal given the social context. This can include an increased interest with another person or an abnormal lack of interest in other people.\nsynonyms :\n'}


{'id': 'HP_5200021', 'url': 'http://purl.obolibrary.org/obo/HP_5200021', 'lbl': 'Reduced social insight', 'desc': 'label: Reduced social insight\ndefinition : A lack of awareness or failure to apply social rules in multiple social settings which are simple or intuitive to others in the same social setting.\nsynonyms :Abnormal social understanding\n'}


{'id': 'HP_5200022', 'url': 'http://purl.obolibrary.org/obo/HP_5200022', 'lbl': 'Reduced awareness of convention', 'desc': 'label: Reduced awareness of convention\ndefinition : Reduced awareness of expected conventions which are normal and expected for particular social settings or interactions.\nsynonyms :\n'}


{'id': 'HP_5200024', 'url': 'http://purl.obolibrary.org/obo/HP_5200024', 'lbl': 'Abnormal relationship', 'desc': "label: Abnormal relationship\ndefinition : The state of having abnormal relationships with others. This does not describe specific aspects of one's social aptitudes but rather a state which may come about from these aptitudes, such as lacking peer relationships, lacking close friends, or having a relational network that is abnormal given one's cultural context.\nsynonyms :\n"}


{'id': 'HP_5200025', 'url': 'http://purl.obolibrary.org/obo/HP_5200025', 'lbl': 'Abnormal social awareness', 'desc': 'label: Abnormal social awareness\ndefinition : Reduced or lack of awareness of social cues or context as is appropriate given social and cultural norms.\nsynonyms :\n'}


{'id': 'HP_5200026', 'url': 'http://purl.obolibrary.org/obo/HP_5200026', 'lbl': 'Abnormal social imitation', 'desc': 'label: Abnormal social imitation\ndefinition : An inability to imitate a task or the movements of others.\nsynonyms :\n'}


{'id': 'HP_5200027', 'url': 'http://purl.obolibrary.org/obo/HP_5200027', 'lbl': 'Abnormal social initiation', 'desc': "label: Abnormal social initiation\ndefinition : An abnormality in one's tendency to initiate social interactions.\nsynonyms :\n"}


{'id': 'HP_5200028', 'url': 'http://purl.obolibrary.org/obo/HP_5200028', 'lbl': 'Abnormal social response', 'desc': 'label: Abnormal social response\ndefinition : Abnormality in the way one responds to social cues such as a verbal cue (which should cause one to shift attention) or someone sharing their emotions (which should elicit a sympathetic response).\nsynonyms :\n'}


{'id': 'HP_5200029', 'url': 'http://purl.obolibrary.org/obo/HP_5200029', 'lbl': 'Social disinhibition', 'desc': 'label: Social disinhibition\ndefinition : A lack of social constraint shown when one acts on tendencies or desires when doing so breaks a social rule or norm. For example, when someone asks personal questions because of their curiosity, despite their private nature and the discomfort the questions may cause others.\nsynonyms :\n'}


{'id': 'HP_5200030', 'url': 'http://purl.obolibrary.org/obo/HP_5200030', 'lbl': 'Diminished integration of verbal and non-verbal communicative behavior', 'desc': "label: Diminished integration of verbal and non-verbal communicative behavior\ndefinition : A communicative abnormality where one's nonverbal and verbal communication are poorly integrated. This may occur when verbal and nonverbal communication are intact alone but are abnormal when used together, or an abnormality in the use of typically integrated communication such as the use of beat gestures during speech.\nsynonyms :\n"}


{'id': 'HP_5200031', 'url': 'http://purl.obolibrary.org/obo/HP_5200031', 'lbl': 'Deferred imitation of others', 'desc': 'label: Deferred imitation of others\ndefinition : An inability to imitate a task or the movements of others for a period of time (such as an hour) after one has seen the task or movement.\nsynonyms :\n'}


{'id': 'HP_5200032', 'url': 'http://purl.obolibrary.org/obo/HP_5200032', 'lbl': 'Reduced immediate imitation of others', 'desc': 'label: Reduced immediate imitation of others\ndefinition : An inability to imitate a task or the movements immediately after one has seen the task or movement.\nsynonyms :\n'}


{'id': 'HP_5200035', 'url': 'http://purl.obolibrary.org/obo/HP_5200035', 'lbl': 'Reduced collaborative imaginative play', 'desc': 'label: Reduced collaborative imaginative play\ndefinition : Failure of a child to integrate with peers in imaginative play.\nsynonyms :\n'}


{'id': 'HP_5200036', 'url': 'http://purl.obolibrary.org/obo/HP_5200036', 'lbl': 'Lack of response to verbal cues', 'desc': 'label: Lack of response to verbal cues\ndefinition : A consistent failure to make any response to verbal cues.\nsynonyms :\n'}


{'id': 'HP_5200037', 'url': 'http://purl.obolibrary.org/obo/HP_5200037', 'lbl': 'Reduced sympathetic expression', 'desc': 'label: Reduced sympathetic expression\ndefinition : A reduction in producing a sympathetic response where a sympathetic response may expect, such as providing comfort when someone is sad or crying.\nsynonyms :\n'}


{'id': 'HP_5200038', 'url': 'http://purl.obolibrary.org/obo/HP_5200038', 'lbl': 'Bradylalia', 'desc': 'label: Bradylalia\ndefinition : Slow speech.\nsynonyms :\n'}


{'id': 'HP_5200039', 'url': 'http://purl.obolibrary.org/obo/HP_5200039', 'lbl': 'Speech too loud for context', 'desc': 'label: Speech too loud for context\ndefinition : Speech too loud for context.\nsynonyms :\n'}


{'id': 'HP_5200040', 'url': 'http://purl.obolibrary.org/obo/HP_5200040', 'lbl': 'Speech too soft for context', 'desc': 'label: Speech too soft for context\ndefinition : Speech too soft for context.\nsynonyms :\n'}


{'id': 'HP_5200043', 'url': 'http://purl.obolibrary.org/obo/HP_5200043', 'lbl': 'Abnormal speech volume', 'desc': 'label: Abnormal speech volume\ndefinition : Speech that is abnormally loud or quiet for the social context in which it is spoken.\nsynonyms :\n'}


{'id': 'HP_5200044', 'url': 'http://purl.obolibrary.org/obo/HP_5200044', 'lbl': 'Reduced attention regulation', 'desc': "label: Reduced attention regulation\ndefinition : Abnormality in one's ability to control their attention toward a specific subject or task. This could include the inability to change attention or hold attention.\nsynonyms :\n"}


{'id': 'HP_5200045', 'url': 'http://purl.obolibrary.org/obo/HP_5200045', 'lbl': 'Reduced impulse control', 'desc': 'label: Reduced impulse control\ndefinition : Reduced ability to control, or a failure to resist a temptation, urge, or impulse.\nsynonyms :Impaired self-restraint; Impulse control disorders\n'}


{'id': 'HP_5200046', 'url': 'http://purl.obolibrary.org/obo/HP_5200046', 'lbl': 'Sensory behavioral abnormality', 'desc': 'label: Sensory behavioral abnormality\ndefinition : Abnormal behavior consisting seeking specific sensory stimulation or an abnormal avoidance of a specific sensory stimulation.\nsynonyms :\n'}