{'id': 'HP_0031572', 'url': 'http://purl.obolibrary.org/obo/HP_0031572', 'lbl': 'Tessier number 1 facial cleft', 'desc': "label: Tessier number 1 facial cleft\ndefinition : As seen in a typical cleft lip, a cleft of the lip is found in the region of the cupid's bow. The nostril is cleft through the alar dome and extends above onto the nasal dorsum. It passes medial to a normal, but dys- topic, medial canthus. There is an alveolar cleft between the central and lateral incisors that extends above through the pyriform margin lateral to the anterior nasal spine; the nasal septum is not involved. The bony cleft extends through the nasal bone or between the junction of the nasal bone and frontal process of the maxilla. Above the cleft lip, the clefting of the alar dome is associated with deviation to the opposite side of the shortened and broadened columella and nasal tip. Extension of the soft tissue cleft onto the nasal dorsum can be manifest as a series of vertical soft tissue furrows and ridges. Vertical inner canthal dysto- pia and severe telecanthus mark the superior aspect of the Number 1 facial cleft. A cranial soft tissue extension characterized by a tongue-like projection of the frontal hairline delineates the number 13 cleft. Skeletal clefting of the maxilla may extend posteriorly to form a complete cleft of the hard and soft palate. The maxilla is hypoplastic in all three dimensions. There is a keel-shaped alveolus and anterior open bite. Normal septation is preserved between the nasal cavity and the hypoplastic maxillary antrum on the affected side. Distortion of the nasal skeleton produces gross flattening of the nasal dorsum. There is asymmetry of the pterygoid plates, of the greater and lesser wings of the sphenoid, and of the floor of the anterior cranial fossa. The distortion of the cranial base may result in a mild plagiocephaly.\nsynonyms :\n"}


{'id': 'HP_0031573', 'url': 'http://purl.obolibrary.org/obo/HP_0031573', 'lbl': 'Tessier number 2 facial cleft', 'desc': 'label: Tessier number 2 facial cleft\ndefinition : As is typically seen in isolated cleft cases, a cleft of the lip is present. There is hypoplasia, but not true notching of the ala nasi with flattening of the lateral part of the nose. The nasal root is broadened, with lateral displacement of the inner canthus. The palpebral fissure and lacrimal drainage system are not disturbed. The alveolar cleft is through the lateral incisor area and extends to the pyriform aperture. There is normal septation between the nasal cavity and maxillary sinus. Notching at the junction between the nasal bone is present, as is a broad, flat frontal process of the maxilla. Transverse ethmoid enlargement produces orbital hypertelorism. Above the cleft of the lip and palate is a true broad cleft of the nostril that is medial to the intact, but laterally displaced, tail of the alar cartilage. A shallow soft tissue groove extends superiorly to the asymmetrically widened nasal root. The lacrimal system, palpebral fissures, and eyebrows remain intact. The alveolar cleft extends posteriorly as a complete unilateral cleft of the hard and soft palate. The nasal septum is intact but deviated to the opposite side. The nasal cavity remains separated from the normally pneumatized, although hypoplastic, maxilla on the cleft side. Above the nasomaxillary notching, the ethmoid sinus is less well developed, and there is no pneumatization of the frontal sinus on this side. Anterior rotation of the greater and lesser wings of the sphenoid occurs on the cleft side in relation to the narrower orbit and smaller ethmoid sinus. There is mild asymmetry of the anterior cranial fossa, which is narrower on the cleft side. The cranium is brachycephalic with marked occipital flattening.\nsynonyms :\n'}


{'id': 'HP_0031574', 'url': 'http://purl.obolibrary.org/obo/HP_0031574', 'lbl': 'Orbital cleft', 'desc': 'label: Orbital cleft\ndefinition : A facial cleft characterized by involvement of the orbit.\nsynonyms :\n'}


{'id': 'HP_0031575', 'url': 'http://purl.obolibrary.org/obo/HP_0031575', 'lbl': 'Tessier number 3 facial cleft', 'desc': 'label: Tessier number 3 facial cleft\ndefinition : As in the Number 1 and Number 2 clefts, this cleft extends through the lip in the region of the typical cleft lip; however, it does not extend through the base. The cleft continues superiorly to involve the inner canthus and lower eyelid medial to the inferior lacrimal punctum, thereby disrupting the nasolacrimal system. Microphthalmia may be present. The alveolar cleft is between the lateral incisor and the canine. Absent septation between the nasal cavity and maxillary antrum, together with the distortion of the frontal process of the maxilla and lacrimal fossa, produces direct communication between the orbit, maxillary sinus, and nose. There is hypoplasia of the soft tissue margins of the cleft in the vertical dimension. This produces extreme soft tissue deficiency between the alar base and the cleft of the medial aspect of the lower eyelid. The inferior lacrimal punctum is evident at the lateral margin of the lower eyelid cleft. The lacrimal drainage system ends as an opening directly onto the cheek without communication into the nasal cavity. The globe is normal in size, but it is displaced inferiorly and laterally. The nasal septum shows the characteristic distortion seen in typical cleft lip and palate. There is absence of septation between the nasal cavity on the cleft side and the maxilla. The maxilla is hypoplastic in three dimensions, with a marked reduction in pneumatization. Superior extension of the skeletal clefting into the medial portion of the orbital floor and into the inferior orbital rim in the region of the frontal process of the maxilla allows direct communication between the orbit above and the nasomaxillary region below. There is mild narrowing of the ethmoid sinus and of the body of the sphenoid on the cleft side. The pterygoid process appears anatomically normal, but less displaced from the midline compared with that of the noncleft side. Both the orbit and the floor of the anterior cranial fossa are inferiorly displaced.\nsynonyms :\n'}


{'id': 'HP_0031576', 'url': 'http://purl.obolibrary.org/obo/HP_0031576', 'lbl': 'Tessier number 4 facial cleft', 'desc': 'label: Tessier number 4 facial cleft\ndefinition : The cleft lip is midway between the philtral ridge and the commissure of the mouth. The cleft is lateral to the normally shaped and placed nasal ala and passes onto the cheek. The cleft extends through the lower eyelid lateral to the punctum. The lacrimal system and inner canthus are normal. Microphthalmia may be present. The alveolar cleft passes between the lateral incisor and canine, as in the Number 3 cleft. The cleft passes around the pyriform aperture and continues through the portion of the maxillary sinus medial to the infraorbital foramen. The cleft terminates at the medial end of the inferior orbital rim. There is severe vertical soft tissue deficiency in a Number 4 cleft, with the medial margins of the cleft lip extending directly into the medially placed cleft of the lower eyelid. Within the medial segment of the right-sided cleft lip, muscle elements are apparently absent. Muscle bunching is noted in the ipsilateral lateral lip segment, as is seen in a typical unilateral cleft lip. The anatomically normal nasal ala is superiorly displaced in association with a severe deficiency in the overall nasal length. Marked dystopia of the right globe results in its inferior displacement into the medially deficient orbital floor and inferior rim. Both globes are otherwise normal. The complete palatal cleft passes through the maxilla medial to the infraorbital foramen and extends to the medial portion of the inferior orbital rim without evidence of an intact maxillary sinus. Bony septation persists medially, thereby separating the nasal cavity from the orbit, maxillary sinus, and mouth, which are contiguous. Marked midfacial hypoplasia is present. The cleft is manifest as asymmetry of the body of the sphenoid; it is smaller on the right, with asymmetric placement of the pterygoid plates relative to the midline. The orbital floor cleft has no communication with the inferior orbital fissure. The cleft does not extend to the skull base, but there is marked facial asymmetry associated with plagiocephaly.\nsynonyms :\n'}


{'id': 'HP_0031577', 'url': 'http://purl.obolibrary.org/obo/HP_0031577', 'lbl': 'Tessier number 5 facial cleft', 'desc': 'label: Tessier number 5 facial cleft\ndefinition : The cleft of the lip is just medial to the oral commissure and extends across the cheek as a furrow. It ends as a cleft at the junction of the middle and lateral third of the lower eyelid. Microphthalmia is frequently present. The alveolar cleft is through the premolar region and extends superiorly through the orbit at the inferolateral part of the rim and floor. There is a vertical soft tissue deficiency between the lateral portion of the lip and the lower eyelid cleft. The left side of the nose shows vertical shortening, and the left alar base is displaced superiorly. Facial asymmetry secondary to the skeletal abnormality is reflected by a vertical orbital dystopia. However, bothglobes are normal, and there is no abnormality of the upper eyelids, eyebrow, forehead, or frontal hairline. The skeletal clefts vary, ranging from a narrow skeletal furrow that traverses the anterior maxillary wall as on the rightto a broad cleft of the maxilla lateral to the infraorbital foramen and maxillary sinus. This latter cleft enters the inferolateral orbital rim and floor without posterior communication with the inferior orbital fissure on the left side. Medial collapse of the lateral maxillary segments is present bilaterally, with reduction in the transverse dimensions of the maxillary arch. Manifestations of the skeletal disturbance in the sphenoid include a shortening and thickening of the lateral orbital walls in the region of the greater wing and mild asymmetric placement of the pterygoid plates relative to the midline. The right-sided pterygoid plates are smaller and closer to the midline. There is minimal asymmetry of the cranial base and calvarium.\nsynonyms :\n'}


{'id': 'HP_0031578', 'url': 'http://purl.obolibrary.org/obo/HP_0031578', 'lbl': 'Tessier number 6 facial cleft', 'desc': 'label: Tessier number 6 facial cleft\ndefinition : A facial cleft extending from the zygomatic arch to the eye. This zygomaticomaxillary cleft is similar to that typically found in Treacher Collins syndrome. The overlying tissue shows a vertical sclerodermic furrow radiating from the labial commissure or the angle of the mandible across the cheek to a coloboma of the lower eyelid between the middle and lateral one-third. Microphthalmia is not observed. The skeletal cleft is between the maxilla and zygoma; it passes through the inferolateral orbital rim to enter the inferior orbital fissure. No alveolar cleft is present. The zygomatic arch is intact. The soft tissue furrow, which is more apparent on the right, radiates from the oral commissure toward the lateral two-thirds of the lower eyelid. The antimongoloid obliquity of the palpebral fissures is associated with laterally placed lower eyelid clefts and some ectropion. A left-sided anophthalmia is accompanied by adjacent soft tissue hypoplasia and is reflected in a short palpebral fissure, enophthalmos, and minor ptosis of the eyebrow. No abnormality is present in the alveolar arch except for some tilting of the occlusal plane secondary to hypoplasia of the left side of the maxilla. There is a vertical bony groove in the region of the zygomaticomaxillary suture that ends in the inferolateral portion of a small bony orbit. More laterally, the remainder of the zygomatic body and arch is normal in both shape and dimension. The lateral orbital floor is downslanting but intact, and it lacks direct communication with the temporal or infratemporal fossae. The hypoplasia of the left side of the maxilla and orbit is associated with a reduction in the transverse and anteroposterior dimensions of the anterior cranial fossa; mild asymmetry of the middle cranial fossa and calvarium is present. No significant asymmetry of size, shape, or position is present in the sphenoid.\nsynonyms :Tessier facial cleft number 6\n'}


{'id': 'HP_0031579', 'url': 'http://purl.obolibrary.org/obo/HP_0031579', 'lbl': 'Tessier number 7 facial cleft', 'desc': 'label: Tessier number 7 facial cleft\ndefinition : The temporozygomatic Number 7 cleft is found in both Treacher Collins syndrome and hemifacial microsomia. Soft tissue manifestations include macrostomia, malformations of the external and middle ear, temporalis muscle, variable involvement of the seventh cranial nerve (in hemifacial microsomia), and abnormalities of the preauricular hair in Treacher Collins syndrome. The skeletal cleft is through the pterygomaxillary junction, and vertical maxillary hypoplasia is present. In addition, abnormality of the mandibular ramus, coronoid, and condyle and absence of the zygomatic arch are typically present. A soft tissue furrow extends from the macrostomia laterally and superiorly across the cheek toward the preauricular hairline. The lower eyelids are intact. The anatomy of the external ear is normal, and there are no preauricular tags. Bony clefting is through the pterygomaxillary junction with hypoplasia of the alveolar process in the molar region, thereby producing a posterior open bite. The maxilla is hypoplastic, although the maxillary sinuses are symmetrically pneumatized. The hypoplastic zygomatic body arches upward, but then it takes a downward course and is severely malformed and displaced. The zygoma is continuous posteriorly with an apparently normal zygomatic process of the temporal bone. The mandibular condyle and coronoid process are hypoplastic and asymmetric. There is no antegonial notching of the mandible. Marked cranial base asymmetry, with tilting and asymmetric positioning of the temporomandibular articulations, is present. The anatomy of the sphenoid is abnormal, especially on the right where there is no recognizable medial or lateral pterygoid plate.\nsynonyms :Tessier cleft number 7; Tessier facial cleft number 7\n'}


{'id': 'HP_0031580', 'url': 'http://purl.obolibrary.org/obo/HP_0031580', 'lbl': 'Tessier number 8 facial cleft', 'desc': "label: Tessier number 8 facial cleft\ndefinition : The frontozygomatic or Number 8 cleft is found in both Treacher Collins syndrome and the Goldenhar variant of hemifacial microsomia. Skeletal defects are more prominent in Treacher Collins syndrome, whereas the soft tissue clefting is more typical in cases of ''Goldenhar syndrome''. Soft tissue clefting presents as a dermatocele, a true lateral eyelid coloboma with absence of the outer canthus, and anomalies of the globe itself, especially epibulbar cysts in patients with Goldenhar syndrome. The frontozygomatic bony cleft produces absence of the lateral orbital rim; this border now is formed by the hypoplastic greater wing of the sphenoid. The absence of bony support for the outer canthus produces lateral canthal dystopia and the characteristic antimongoloid slant of the palpebral fissures. Secondary to the bony deficiency in the lateral orbital wall and floor, there is soft tissue continuity between the orbit, temporal fossa, and infratemporal region. Preauricular hairline indicators delineate the Number 8 cleft as the first of the northbound clefts. Complete absence of the bony lateral orbital wall and rim constitute the skeletal element of the Number 8 cleft. The lateral border of the orbit is formed by the greater wing of the sphenoid from which small spicules of bone, which represent the rudimentary zygoma, may be found in Treacher Collins syndrome. The symmetry of the facial anomalies is reflected in the apparently normal symmetric anterior and middle cranial fossae.\nsynonyms :Tessier facial cleft number 8\n"}


{'id': 'HP_0031581', 'url': 'http://purl.obolibrary.org/obo/HP_0031581', 'lbl': 'Tessier number 9 facial cleft', 'desc': 'label: Tessier number 9 facial cleft\ndefinition : This is an upper lateral orbital cleft. The soft tissue deformity is in the lateral one-third of the upper eyelid, and the bony cleft is through the superolateral orbital angle. Microphthalmia is present. The superolateral bony deficiency of the orbits allows a lateral displacement of the globes. The lateral one-third of the upper eyelid and the outer canthus are distorted, thus preventing apposition to the globe. The upper eyelid does not have a true cleft. A soft tissue furrow radiates superiorly and posterisphenoid is symmetric and normal. Mild cranial base asymmetry is reflected in the pterygoid plates. The left pair is more laterally displaced from the midline. Skull vault plagiocephaly is evident with an apparent reduction in the anteroposterior dimension of the anterior cranial fossa.\nsynonyms :\n'}


{'id': 'HP_0031582', 'url': 'http://purl.obolibrary.org/obo/HP_0031582', 'lbl': 'Tessier number 10 facial cleft', 'desc': 'label: Tessier number 10 facial cleft\ndefinition : In a Number 10 Tessier cleft there is an upper central orbital cleft with a cleft of the middle one-third of the upper eyelid, which often results in total ablepharia. The eyebrow is disrupted, being virtually absent medially, whereas the lateral portion angles upward toward the frontal hairline. There may be ocular anomalies, including colobomata of the iris. The skeletal cleft is through the midportion of the supraorbital rim, the adjacent frontal bone, and the orbital roof lateral to the supraorbital nerve. A frontal encephalocele frequently occupies the frontal bony cleft. The palpebral fissure is grossly elongated with an amblyopic eye displaced inferiorly and laterally. There is also a divergent squint of the right eye. The eyebrow is deficient medially and becomes thinned out laterally , where it is contiguous with a broad downward and forward projection of the frontotemporal hairline (this may be seen in both the Number 9 and 10 clefts.) A broad frontal encephalocele bulges forward from the middle one-third of the right forehead, supraorbital ridge, and orbital roof. The bony cleft, through which the frontal encephalocele presents, involves the anterior half of the orbital roof, the supraorbital rim, and two-thirds of the vertical height of the frontal bone lateral to the supraorbital nerve. The bony orbit is inferiorly displaced and widened with the lateral orbital wall shortened and laterally deviated. Similar distortion of the anterior cranial fossa is evident, being broader and more flattened on the affected side. The calvarium above the level of the cleft and the cranial base below is symmetric.\nsynonyms :\n'}


{'id': 'HP_0031583', 'url': 'http://purl.obolibrary.org/obo/HP_0031583', 'lbl': 'Tessier number 11 facial cleft', 'desc': 'label: Tessier number 11 facial cleft\ndefinition : An upper medial orbital cleft produces a cleft of the medial one-third of the upper eyelid that extends through the eyebrow into the frontal hairline. The skeletal element of the cleft in the region of the frontal process of the maxilla may either pass lateral to the ethmoid, through the supraorbital rim, or it may pass through the ethmoidal labyrinth to produce orbital hypertelorism. This cleft usually accompanies the Number 3 cleft. The soft tissue features include a cleft of the medial portion of the upper eyelid, an irregularity in hair orientation at the medial end of the eyebrow, and a long tongue-like projection of the frontal hairline onto the forehead. There is a mild flattening of the frontal process of the maxilla and extensive pneumatization of both the ethmoidal and frontal sinuses, both of which are more prominent on the cleft side. No bony clefting of the supraorbital rim or frontal bone is evident. The cranial base and sphenoid architecture, including the pterygoid processes, are symmetric and normal.\nsynonyms :\n'}


{'id': 'HP_0031584', 'url': 'http://purl.obolibrary.org/obo/HP_0031584', 'lbl': 'Tessier number 12 facial cleft', 'desc': 'label: Tessier number 12 facial cleft\ndefinition : There is a soft tissue cleft medial to the inner canthus with a cleft of the root of the eyebrow. The frontal process of the maxilla is flat and broadened, and the ethmoid labyrinth is increased in tranverse dimension, thereby producing orbital hypertelorism. The cribriform plate is of normal width. The frontal sinus is enlarged. Even though the frontal bone is flattened, bony clefts with encephalocele have not been observed. There is a lateral displacement of the inner canthus with a mild thinning, aplasia, or irregularity of the medial end of the eyebrow. There are no eyelid clefts. The soft tissue contour of the forehead is normal, with only a short downward prolongation of the paramedian frontal hairline to mark the superior extent of the soft tissue cleft. Flattening of the frontal process of the maxilla, an increase in the transverse dimension of the ethmoid sinus, and a laterally convex bowing of the medial orbital wall produce orbital hypertelorism. Superiorly there is a minor flattening of the frontal bone medially, and the nasofrontal angle is somewhat obtuse. The extensive pneumatization of the sinuses on the cleft side extends backward through the frontal and ethmoid sinuses and into the sphenoid sinus. The anatomy of the sphenoid, including the pterygoid processes, is otherwise normal. The anterior and middle cranial fossae floors are both broadened on the cleft side with minor widening of the cribriform plate.\nsynonyms :\n'}


{'id': 'HP_0031585', 'url': 'http://purl.obolibrary.org/obo/HP_0031585', 'lbl': 'Tessier number 13 facial cleft', 'desc': "label: Tessier number 13 facial cleft\ndefinition : There is a paramedian frontal encephalocele and a soft tissue cleft that passes medial to an intact eyebrow. The frontal bone shows a paramedian bony cleft with an associated encephalocele. The olfactory groove, cribriform plate, and ethmoid sinus are all increased in transverse diameter, resulting in hypertelorism. The cleft extends medially to the undisturbed eyebrow to end in a short paramedian frontal widow's peak. The bony cleft begins in the region of the nasal bone and extends superiorly through the full height of the frontal bone. Posteriorly, the cleft extends through the cribriform plate and ethmoid sinus as far as the lesser wing and body of the sphenoid. The pterygoid processes are anatomically normal, but they are displaced laterally from the midline on the cleft side. There is orbital hypertelorism below and asymmetry of the floor of the anterior cranial fossa above.\nsynonyms :\n"}


{'id': 'HP_0031586', 'url': 'http://purl.obolibrary.org/obo/HP_0031586', 'lbl': 'Tessier number 14 facial cleft', 'desc': 'label: Tessier number 14 facial cleft\ndefinition : This midline cranial cleft usually occurs with a midline facial cleft that completes a median craniofacial dysraphia. A broad nasal root and bifid nose are associated with orbital hypertelorism and a median frontal encephalocele. The frontal bone abnormality varies from a minor flattening to a large midline defect. There is an increased distance between the olfactory grooves. The crista galli is widened, duplicated, or in some cases absent. Marked inferior prolapse of the enlarged ethmoid bone occurs with orbital hypertelorism. The severe orbital hypertelorism is associated with a broad flattening of the glabella and extreme lateral displacement of the inner canthi. The periorbita, including the eyelids and eyebrows, are otherwise normal. A long midline projection of the frontal hairline marks the superior extent of the soft tissue features of this midline cranial cleft. The median frontal defect delineates the region through which the frontal encephalocele herniates. The lateral segments of the frontal bone sweep upward from the region of the intact glabella and are flattened laterally. No pneumatization of the frontal sinus is evident. The crista galli and the perpendicular plate of the ethmoid are bifid. Just as the ethmoid, including the cribriform plate, is widened and caudally displaced, the sphenoid sinus is broadened and extensively, but symmetrically pneumatized. The lateral rotation of the greater and lesser wings of the sphenoid results in a relative shortening of the anteroposterior dimension of the middle cranial fossa. The floor of the anterior cranial fossa is upslanting from its medial aspect to its lateral aspect, with a harlequin appearance on the coronal scan.\nsynonyms :Tessier facial cleft number 14\n'}


{'id': 'HP_0031587', 'url': 'http://purl.obolibrary.org/obo/HP_0031587', 'lbl': 'Tessier number 30 facial cleft', 'desc': 'label: Tessier number 30 facial cleft\ndefinition : A lower midline facial cleft, also known as the median mandibular cleft. It is a rare anomaly, which may be limited to a defect in the soft tissue of the lower lip. However, in the more severe form, it may extend into the bony mandibular symphysis.\nsynonyms :\n'}


{'id': 'HP_0031588', 'url': 'http://purl.obolibrary.org/obo/HP_0031588', 'lbl': 'Unhappy demeanor', 'desc': 'label: Unhappy demeanor\ndefinition : A conspicuously unhappy disposition characterized by negative assumptions, self-defeating talk, fear of failure, and negative ruminations about past events.\nsynonyms :Unhappy demeanour\n'}


{'id': 'HP_0031589', 'url': 'http://purl.obolibrary.org/obo/HP_0031589', 'lbl': 'Suicidal ideation', 'desc': 'label: Suicidal ideation\ndefinition : Frequent thinking about or preoccupation with killing oneself.\nsynonyms :Suicidality\n'}


{'id': 'HP_0031590', 'url': 'http://purl.obolibrary.org/obo/HP_0031590', 'lbl': 'Asthenopia', 'desc': "label: Asthenopia\ndefinition : Eye strain, i.e., a feeling of fatigue or discomfort of the eyes related to 'overuse' of the eyes in activities such as reading or working at the computer and often accompanied by lacrimation or headache.\nsynonyms :Eye strain\n"}


{'id': 'HP_0031591', 'url': 'http://purl.obolibrary.org/obo/HP_0031591', 'lbl': 'Enlarged Eustachian valve', 'desc': 'label: Enlarged Eustachian valve\ndefinition : An abnormally large Eustachian valve (postnatally). The Eustachian valve is also known as the valve of the inferior vena cava, and is an embryologic remnant of the valve of the inferior vena cava.\nsynonyms :Enlarged inferior vena cava valve; Giant Eustachian valve\n'}


{'id': 'HP_0031592', 'url': 'http://purl.obolibrary.org/obo/HP_0031592', 'lbl': 'Situs inversus with levocardia', 'desc': 'label: Situs inversus with levocardia\ndefinition : Situs inversus of thoracic and abdominal viscera with the heart remaining normally situated on the left; usually associated with congenital cardiac abnormalities such as transposition of the great vessels and/or spleen defects including asplenia or polysplenia.\nsynonyms :\n'}


{'id': 'HP_0031593', 'url': 'http://purl.obolibrary.org/obo/HP_0031593', 'lbl': 'Abnormal PR interval', 'desc': 'label: Abnormal PR interval\ndefinition : An anomaly of the PR interval, which is the portion of the ECG from the onset of the P wave to the beginning of the QRS complex. A normal PR interval in adults is 0.12-0.2 seconds.\nsynonyms :\n'}


{'id': 'HP_0031594', 'url': 'http://purl.obolibrary.org/obo/HP_0031594', 'lbl': 'PR segment depression', 'desc': 'label: PR segment depression\ndefinition : A reduction in voltage of the PR segment below baseline.\nsynonyms :PR interval depression; PTa depression\n'}


{'id': 'HP_0031595', 'url': 'http://purl.obolibrary.org/obo/HP_0031595', 'lbl': 'Abnormal P wave', 'desc': 'label: Abnormal P wave\ndefinition : Any anomaly of the P wave of the EKG, which results from atrial depolarization. The P wave occurs when the sinoatrial node creates an action potential that depolarizes the atria.\nsynonyms :\n'}


{'id': 'HP_0031596', 'url': 'http://purl.obolibrary.org/obo/HP_0031596', 'lbl': 'Abnormal PR segment', 'desc': 'label: Abnormal PR segment\ndefinition : An anomaly of the PR segment, which begins at the endpoint of the P wave and ends at the onset of the QRS complex. The PR segment is normally flat and isoelectric.\nsynonyms :\n'}


{'id': 'HP_0031597', 'url': 'http://purl.obolibrary.org/obo/HP_0031597', 'lbl': 'PR segment elevation', 'desc': 'label: PR segment elevation\ndefinition : An increase in voltage of the PR segment above baseline.\nsynonyms :PR interval elevation; PTa elevation\n'}


{'id': 'HP_0031598', 'url': 'http://purl.obolibrary.org/obo/HP_0031598', 'lbl': 'Notched P wave', 'desc': 'label: Notched P wave\ndefinition : V-shaped cut (notch) in the middle of the P wave.\nsynonyms :\n'}


{'id': 'HP_0031599', 'url': 'http://purl.obolibrary.org/obo/HP_0031599', 'lbl': 'P mitrale', 'desc': 'label: P mitrale\ndefinition : A broad (120 ms or longer in duration) and bifid P-wave in EKG lead II.\nsynonyms :\n'}


{'id': 'HP_0031600', 'url': 'http://purl.obolibrary.org/obo/HP_0031600', 'lbl': 'P wave inversion', 'desc': 'label: P wave inversion\ndefinition : P wave below instead of above the baseline. P-wave inversion in the inferior leads may indicate a non-sinus origin of the P waves.\nsynonyms :\n'}


{'id': 'HP_0031601', 'url': 'http://purl.obolibrary.org/obo/HP_0031601', 'lbl': 'P pulmonale', 'desc': 'label: P pulmonale\ndefinition : The presence of tall, peaked P waves in EKG lead II.\nsynonyms :\n'}


{'id': 'HP_0031602', 'url': 'http://purl.obolibrary.org/obo/HP_0031602', 'lbl': 'Abnormal mucociliary clearance', 'desc': 'label: Abnormal mucociliary clearance\ndefinition : An anomaly in the system of mucociliary transport, which functions to transport the mucous layer lining the respiratory epithelium by ciliary \nbeating.\nsynonyms :Abnormal mucociliary transport\n'}


{'id': 'HP_0031603', 'url': 'http://purl.obolibrary.org/obo/HP_0031603', 'lbl': 'Impaired nasal mucociliary clearance', 'desc': 'label: Impaired nasal mucociliary clearance\ndefinition : An abnormally increased amount of time required to clear mucus (and substances contained in the mucus) from the nasal mucosa. The nasal mucociliary clearance (NMC) system functions to transport the mucous layer lining the nasal epithelium towards the naso pharynx by ciliary beating in a metachronous fashion at a frequency of 7-16 Hz. NMC depends upon two principal components: physicochemical qualities and quantities of mucus and the properties of cilia that propel it. NMC is considered to be representative of pulmonary clearance. normal NMC time is determined to be up to 20 minutes. Duration of 30 minutes is considered as the cutoff point that discriminates normal subjects from subjects with impaired NMC. NMC can be measured by determination of the transport time of markers that are placed on the nasal mucosa including saccharine, radioactive markers, and dyes.\nsynonyms :Abnormal saccharine test\n'}


{'id': 'HP_0031604', 'url': 'http://purl.obolibrary.org/obo/HP_0031604', 'lbl': 'Agenesis of the carotid canal', 'desc': 'label: Agenesis of the carotid canal\ndefinition : A developmental defect characterized by the lack of formation of the carotid canal, which normally is a circular aperture in the temporal bone of the skull through which the internal carotid artery and the carotid plexus of nerves traverse.\nsynonyms :Bony carotid canal agenesis\n'}


{'id': 'HP_0031605', 'url': 'http://purl.obolibrary.org/obo/HP_0031605', 'lbl': 'Abnormality of fundus pigmentation', 'desc': 'label: Abnormality of fundus pigmentation\ndefinition : Any anomaly of the pigmentation of the fundus, the posterior part of the eye including the retina and optic nerve.\nsynonyms :\n'}


{'id': 'HP_0031606', 'url': 'http://purl.obolibrary.org/obo/HP_0031606', 'lbl': 'Retinal cotton wool spot', 'desc': 'label: Retinal cotton wool spot\ndefinition : Fluffy white patch on the retina, representing localized areas of dense white swelling of the retinal nerve fibre layer. They often have a zigzag internal structure, a feathered edge but an otherwise well-delineated form and an approximately 1 mm dimension; they project slightly into the vitreous and sometimes deflect retinal vessels.\nsynonyms :\n'}


{'id': 'HP_0031607', 'url': 'http://purl.obolibrary.org/obo/HP_0031607', 'lbl': 'Pelvic organ prolapse', 'desc': 'label: Pelvic organ prolapse\ndefinition : Weakness in the supporting structures of the pelvic floor allowing the pelvic viscera to descend or one or more of the pelvic organs drop from their normal position.\nsynonyms :\n'}


{'id': 'HP_0031609', 'url': 'http://purl.obolibrary.org/obo/HP_0031609', 'lbl': 'Geographic atrophy', 'desc': 'label: Geographic atrophy\ndefinition : Sharply demarcated area of partial or complete depigmentation of the fundus reflecting atrophy of the retinal pigment epithelium with associated retinal photoreceptor loss. The margins of the de-pigmented area are usually scalloped and the large choroidal vessels are visible through the atrophic retinal pigment epithelium.\nsynonyms :\n'}


{'id': 'HP_0031610', 'url': 'http://purl.obolibrary.org/obo/HP_0031610', 'lbl': 'Recurrent shoulder dislocation', 'desc': 'label: Recurrent shoulder dislocation\ndefinition : Shoulder dislocation occurring repeated times.\nsynonyms :Multiple shoulder dislocation\n'}


{'id': 'HP_0031611', 'url': 'http://purl.obolibrary.org/obo/HP_0031611', 'lbl': 'Sub-inner limiting membrane hemorrhage', 'desc': 'label: Sub-inner limiting membrane hemorrhage\ndefinition : A type of intraretinal hemorrhage that is located in the superficial retina between the inner limiting membrane and the retinal nerve fiber layer.\nsynonyms :Sub-ILM haemorrhage; Sub-ILM hemorrhage; Sub-inner limiting membrane haemorrhage\n'}


{'id': 'HP_0031613', 'url': 'http://purl.obolibrary.org/obo/HP_0031613', 'lbl': 'Inferior chorioretinal coloboma', 'desc': 'label: Inferior chorioretinal coloboma\ndefinition : Absence of a region of the retina, retinal pigment epithelium, and choroid at the lower part of the fundus.\nsynonyms :\n'}


{'id': 'HP_0031614', 'url': 'http://purl.obolibrary.org/obo/HP_0031614', 'lbl': 'Inferior retinal coloboma', 'desc': 'label: Inferior retinal coloboma\ndefinition : A notch or cleft of the lower part of the retina.\nsynonyms :\n'}


{'id': 'HP_0031615', 'url': 'http://purl.obolibrary.org/obo/HP_0031615', 'lbl': 'Hypopyon', 'desc': 'label: Hypopyon\ndefinition : Presence of pus (appears as a white fluid) producing a fluid level in the inferior part of the anterior chamber.\nsynonyms :\n'}


{'id': 'HP_0031616', 'url': 'http://purl.obolibrary.org/obo/HP_0031616', 'lbl': 'Anterior chamber flare', 'desc': 'label: Anterior chamber flare\ndefinition : An abnormal appearance of the beam of light traveling through the anterior chamber of the eye in a slit lamp examination. The flare is produced by an increased concentration of proteins in the aqueous humor in the anterior chamber.\nsynonyms :\n'}


{'id': 'HP_0031618', 'url': 'http://purl.obolibrary.org/obo/HP_0031618', 'lbl': 'Anterior chamber flare grade 1+', 'desc': 'label: Anterior chamber flare grade 1+\ndefinition : Faint anterior chamber flare.\nsynonyms :\n'}


{'id': 'HP_0031619', 'url': 'http://purl.obolibrary.org/obo/HP_0031619', 'lbl': 'Anterior chamber flare grade 2+', 'desc': 'label: Anterior chamber flare grade 2+\ndefinition : Moderate anterior chamber flare (iris and lens details clear).\nsynonyms :\n'}


{'id': 'HP_0031620', 'url': 'http://purl.obolibrary.org/obo/HP_0031620', 'lbl': 'Anterior chamber flare grade 3+', 'desc': 'label: Anterior chamber flare grade 3+\ndefinition : Marked anterior chamber flare (iris and lens details hazy).\nsynonyms :\n'}


{'id': 'HP_0031621', 'url': 'http://purl.obolibrary.org/obo/HP_0031621', 'lbl': 'Anterior chamber flare grade 4+', 'desc': 'label: Anterior chamber flare grade 4+\ndefinition : Intense anterior chamber flare (fibrin/plastic aqueous).\nsynonyms :\n'}


{'id': 'HP_0031622', 'url': 'http://purl.obolibrary.org/obo/HP_0031622', 'lbl': 'Brown anomaly', 'desc': 'label: Brown anomaly\ndefinition : An ocular motility defect where the affected eye(s) does not elevate in adduction but has full depression in adduction. It can be congenital or acquired from injury to or defect of the superior oblique tendon or trochlea and has a positive forced duction test result.\nsynonyms :Brown syndrome\n'}


{'id': 'HP_0031623', 'url': 'http://purl.obolibrary.org/obo/HP_0031623', 'lbl': 'Brow ptosis', 'desc': 'label: Brow ptosis\ndefinition : Drooping of the upper eyebrow below the superior orbital rim.\nsynonyms :Drooping brow\n'}


{'id': 'HP_0031624', 'url': 'http://purl.obolibrary.org/obo/HP_0031624', 'lbl': 'Moderate myopia', 'desc': 'label: Moderate myopia\ndefinition : A moderate form of myopia with refractive error of between -3.00 and -6.00 diopters.\nsynonyms :\n'}


{'id': 'HP_0031625', 'url': 'http://purl.obolibrary.org/obo/HP_0031625', 'lbl': 'Pseudoaneurysm', 'desc': 'label: Pseudoaneurysm\ndefinition : A contained rupture of an artery with a disruption in all 3 layers of the arterial wall.\nsynonyms :\n'}


{'id': 'HP_0031626', 'url': 'http://purl.obolibrary.org/obo/HP_0031626', 'lbl': 'Coronary ostial atresia', 'desc': 'label: Coronary ostial atresia\ndefinition : Absence of the normal opening of a coronary ostium. There are normally two coronary ostia, which are site of origin of the main left or right main coronary artery and are located in the ascending aorta just above the aortic valve.\nsynonyms :Atresia of coronary ostium\n'}


{'id': 'HP_0031627', 'url': 'http://purl.obolibrary.org/obo/HP_0031627', 'lbl': 'Globus pallidus calcification', 'desc': 'label: Globus pallidus calcification\ndefinition : Pathological deposition of calcium salts in the globus pallidus.\nsynonyms :\n'}


{'id': 'HP_0031628', 'url': 'http://purl.obolibrary.org/obo/HP_0031628', 'lbl': 'Aborted sudden cardiac death', 'desc': 'label: Aborted sudden cardiac death\ndefinition : Cardiac arrest that would have led to rapid and unexpected death had an intervention not taken place to prevent it.\nsynonyms :Sudden cardiac arrest\n'}


{'id': 'HP_0031629', 'url': 'http://purl.obolibrary.org/obo/HP_0031629', 'lbl': 'Impaired tandem gait', 'desc': 'label: Impaired tandem gait\ndefinition : Reduced ability to walk in a straight line while placing the feet heel to toe.\nsynonyms :Clumsy tandem walking\n'}


{'id': 'HP_0031630', 'url': 'http://purl.obolibrary.org/obo/HP_0031630', 'lbl': 'Abnormal subpleural morphology', 'desc': 'label: Abnormal subpleural morphology\ndefinition : Any structural anomaly located between the pleura and the chest wall.\nsynonyms :\n'}


{'id': 'HP_0031631', 'url': 'http://purl.obolibrary.org/obo/HP_0031631', 'lbl': 'Subpleural honeycombing', 'desc': 'label: Subpleural honeycombing\ndefinition : So-called honeycombs (variably sized cysts in a background of densely scarred tissue) located in the subpleural space.\nsynonyms :\n'}


{'id': 'HP_0031632', 'url': 'http://purl.obolibrary.org/obo/HP_0031632', 'lbl': 'Anomalous origin of the right subclavian artery from the descending aorta', 'desc': 'label: Anomalous origin of the right subclavian artery from the descending aorta\ndefinition : Abnormal origin of the right subclavian artery from the descending aorta. The right subclavian artery normally arises from the brachiocephalic trunk, which divides into the right common carotid artery and right subclavian artery.\nsynonyms :\n'}


{'id': 'HP_0031633', 'url': 'http://purl.obolibrary.org/obo/HP_0031633', 'lbl': 'Isolation of the left subclavian artery', 'desc': 'label: Isolation of the left subclavian artery\ndefinition : The loss of continuity between the left subclavian artery and the aorta, with persistent connection to the homolateral pulmonary artery through the patent (PDA) or nonpatent ductus arteriosus.\nsynonyms :\n'}


{'id': 'HP_0031634', 'url': 'http://purl.obolibrary.org/obo/HP_0031634', 'lbl': 'Anomalous origin of the left common carotid artery from the main pulmonary artery', 'desc': 'label: Anomalous origin of the left common carotid artery from the main pulmonary artery\ndefinition : The left common carotid artery normally originates from the aortic arch. This term refers to an origin of this artery from the main pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0031635', 'url': 'http://purl.obolibrary.org/obo/HP_0031635', 'lbl': 'Anomalous origin of the left common carotid artery from the brachiocephalic artery', 'desc': 'label: Anomalous origin of the left common carotid artery from the brachiocephalic artery\ndefinition : The left common carotid artery normally originates from the aortic arch. This term refers to an origin of this artery from the brachiocephalic artery.\nsynonyms :Anomalous origin of the left common carotid artery from the brachiocephalic trunk\n'}


{'id': 'HP_0031636', 'url': 'http://purl.obolibrary.org/obo/HP_0031636', 'lbl': 'Anomalous origin of the right common carotid artery from the aorta', 'desc': 'label: Anomalous origin of the right common carotid artery from the aorta\ndefinition : The right common carotid artery normally originates from the brachiocephalic artery. This term refers to an origin of this artery directly from the aorta.\nsynonyms :\n'}


{'id': 'HP_0031637', 'url': 'http://purl.obolibrary.org/obo/HP_0031637', 'lbl': 'Right coronary artery ostial atresia', 'desc': 'label: Right coronary artery ostial atresia\ndefinition : Absence of the normal opening of the coronary ostium from which the right main coronary artery originates.\nsynonyms :\n'}


{'id': 'HP_0031638', 'url': 'http://purl.obolibrary.org/obo/HP_0031638', 'lbl': 'Anomalous origin of the left anterior descending artery from the pulmonary artery', 'desc': 'label: Anomalous origin of the left anterior descending artery from the pulmonary artery\ndefinition : The left anterior descending artery (LAD) branches off from the pulmonary artery.\nsynonyms :\n'}


{'id': 'HP_0031639', 'url': 'http://purl.obolibrary.org/obo/HP_0031639', 'lbl': 'Absent left main coronary artery', 'desc': 'label: Absent left main coronary artery\ndefinition : The left main coronary artery (LMCA) is absent and the left anterior descending (LAD) and left circumflex (LCX) arteries arise from separate but adjacent ostia in the left sinus of Valsava.\nsynonyms :Absent LMCA\n'}


{'id': 'HP_0031640', 'url': 'http://purl.obolibrary.org/obo/HP_0031640', 'lbl': 'Abnormal radial artery morphology', 'desc': 'label: Abnormal radial artery morphology\ndefinition : Any structural anomaly of the radial artery.\nsynonyms :\n'}


{'id': 'HP_0031643', 'url': 'http://purl.obolibrary.org/obo/HP_0031643', 'lbl': 'Fusiform ascending tubular aorta aneurysm', 'desc': 'label: Fusiform ascending tubular aorta aneurysm\ndefinition : A concentric abnormal localized widening (dilatation) of the ascending tubular aorta that involves the full circumference of the vessel wall.\nsynonyms :\n'}


{'id': 'HP_0031644', 'url': 'http://purl.obolibrary.org/obo/HP_0031644', 'lbl': 'Fusiform abdominal aortic aneurysm', 'desc': 'label: Fusiform abdominal aortic aneurysm\ndefinition : A concentric abnormal localized widening (dilatation) of the abdominal aorta that involves the full circumference of the vessel wall\nsynonyms :\n'}


{'id': 'HP_0031645', 'url': 'http://purl.obolibrary.org/obo/HP_0031645', 'lbl': 'Saccular abdominal aortic aneurysm', 'desc': 'label: Saccular abdominal aortic aneurysm\ndefinition : An eccentric abnormal localized widening (dilatation) of the abdominal aorta that involves only a portion of the circumference of the vessel wall.\nsynonyms :\n'}


{'id': 'HP_0031646', 'url': 'http://purl.obolibrary.org/obo/HP_0031646', 'lbl': 'Fusiform aortic arch aneurysm', 'desc': 'label: Fusiform aortic arch aneurysm\ndefinition : A concentric abnormal localized widening (dilatation) of the aortic arch that involves the full circumference of the vessel wall.\nsynonyms :\n'}


{'id': 'HP_0031647', 'url': 'http://purl.obolibrary.org/obo/HP_0031647', 'lbl': 'Saccular aortic arch aneurysm', 'desc': 'label: Saccular aortic arch aneurysm\ndefinition : An eccentric abnormal localized widening (dilatation) of the aortic arch that involves only a portion of the circumference of the vessel wall.\nsynonyms :\n'}


{'id': 'HP_0031648', 'url': 'http://purl.obolibrary.org/obo/HP_0031648', 'lbl': 'Penetrating aortic ulcer', 'desc': 'label: Penetrating aortic ulcer\ndefinition : A focal defect in the elastic lamina of the aortic wall that leads to localized medial disruption and potential rupture.\nsynonyms :\n'}


{'id': 'HP_0031649', 'url': 'http://purl.obolibrary.org/obo/HP_0031649', 'lbl': 'Aortic rupture', 'desc': 'label: Aortic rupture\ndefinition : Tearing of the aortic wall generally associated with profuse internal bleeding.\nsynonyms :\n'}


{'id': 'HP_0031650', 'url': 'http://purl.obolibrary.org/obo/HP_0031650', 'lbl': 'Abnormal atrioventricular valve physiology', 'desc': 'label: Abnormal atrioventricular valve physiology\ndefinition : Any functional defect of the mitral or tricuspid valve.\nsynonyms :\n'}


{'id': 'HP_0031651', 'url': 'http://purl.obolibrary.org/obo/HP_0031651', 'lbl': 'Abnormal tricuspid valve physiology', 'desc': 'label: Abnormal tricuspid valve physiology\ndefinition : Any functional defect of the tricuspid valve.\nsynonyms :\n'}


{'id': 'HP_0031652', 'url': 'http://purl.obolibrary.org/obo/HP_0031652', 'lbl': 'Abnormal aortic valve physiology', 'desc': 'label: Abnormal aortic valve physiology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031653', 'url': 'http://purl.obolibrary.org/obo/HP_0031653', 'lbl': 'Abnormal heart valve physiology', 'desc': 'label: Abnormal heart valve physiology\ndefinition : Any functional abnormality of a cardiac valve.\nsynonyms :\n'}


{'id': 'HP_0031654', 'url': 'http://purl.obolibrary.org/obo/HP_0031654', 'lbl': 'Abnormal pulmonary valve physiology', 'desc': 'label: Abnormal pulmonary valve physiology\ndefinition : Any functional anomaly of the pumonary valve.\nsynonyms :\n'}


{'id': 'HP_0031655', 'url': 'http://purl.obolibrary.org/obo/HP_0031655', 'lbl': 'Quadricuspid aortic valve', 'desc': 'label: Quadricuspid aortic valve\ndefinition : The presence of an aortic valve with four instead of the normal three cusps (flaps).\nsynonyms :\n'}


{'id': 'HP_0031656', 'url': 'http://purl.obolibrary.org/obo/HP_0031656', 'lbl': 'Systolic anterior motion of the mitral valve', 'desc': 'label: Systolic anterior motion of the mitral valve\ndefinition : Systolic anterior motion of the mitral valve (SAM) is a paradoxical motion of the anterior, and occasionally posterior, mitral valve leaflet towards the left ventricular outflow tract (LVOT) during systole.\nsynonyms :\n'}


{'id': 'HP_0031657', 'url': 'http://purl.obolibrary.org/obo/HP_0031657', 'lbl': 'Abnormal heart sound', 'desc': 'label: Abnormal heart sound\ndefinition : Any abnormal noise generated by the beating heart.\nsynonyms :\n'}


{'id': 'HP_0031658', 'url': 'http://purl.obolibrary.org/obo/HP_0031658', 'lbl': 'Third heart sound', 'desc': 'label: Third heart sound\ndefinition : The third heart sound (S3) is related to rapid filling in diastole. S3 can be a normal finding in children and adolescents but suggests heart failure in older patients.\nsynonyms :S3; Ventricular gallop\n'}


{'id': 'HP_0031659', 'url': 'http://purl.obolibrary.org/obo/HP_0031659', 'lbl': 'Fourth heart sound', 'desc': 'label: Fourth heart sound\ndefinition : The fourth heart sound (S4) is a low-pitched sound that occurs just before the first heart sound (S1) when the atria contract to force blood into the left ventricle, that is, coincident with late diastolic filling of the ventricle due to atrial contraction.\nsynonyms :Atrial gallop; Presystolic gallop; S4\n'}


{'id': 'HP_0031660', 'url': 'http://purl.obolibrary.org/obo/HP_0031660', 'lbl': 'Loud first heart sound', 'desc': 'label: Loud first heart sound\ndefinition : Abnormally increased volume of the first heart sound.\nsynonyms :\n'}


{'id': 'HP_0031661', 'url': 'http://purl.obolibrary.org/obo/HP_0031661', 'lbl': 'Abnormal second heart sound', 'desc': 'label: Abnormal second heart sound\ndefinition : Any anomaly of the second heart sound (S2), which is produced by aortic (A2) and pulmonic (P2) valve closure. The A2-P2 interval normally increases with inspiration and narrows with expiration.\nsynonyms :\n'}


{'id': 'HP_0031662', 'url': 'http://purl.obolibrary.org/obo/HP_0031662', 'lbl': 'Fixed splitting of the second heart sound', 'desc': 'label: Fixed splitting of the second heart sound\ndefinition : Lack of variation in the splitting between the two components of the second heart sound with respiration. Normally, the aortic valve closure (A2) is followed by the pulmonic valve closure (P2) but the A2-P2 interval increases with inspiration and decreases with expiration.\nsynonyms :Fixed splitting of S2\n'}


{'id': 'HP_0031663', 'url': 'http://purl.obolibrary.org/obo/HP_0031663', 'lbl': 'Paradoxical splitting of the second heart sound', 'desc': 'label: Paradoxical splitting of the second heart sound\ndefinition : Normally, the aortic valve closure (A2) is followed by the pulmonic valve closure (P2) but the A2-P2 interval increases with inspiration and decreases with expiration. With paradoxical splitting, there is a delay in the closure of the aortic valve, so that A2 can follow P2; the individual components can be appreciated at the end of expiration and the interval narrows with inspiration (which is the oposite of the normal pattern).\nsynonyms :Paradoxical splitting of S2; Reversed splitting of S2; Reversed splitting of the second heart sound\n'}


{'id': 'HP_0031664', 'url': 'http://purl.obolibrary.org/obo/HP_0031664', 'lbl': 'Systolic heart murmur', 'desc': 'label: Systolic heart murmur\ndefinition : A heart murmur limited to systole, i.e., between the first and second heart sounds S1 and S2.\nsynonyms :\n'}


{'id': 'HP_0031665', 'url': 'http://purl.obolibrary.org/obo/HP_0031665', 'lbl': 'Midsystolic murmur', 'desc': 'label: Midsystolic murmur\ndefinition : A systolic murmur that begins after S1 and ends before S2, typically with a crescendo-decrescendo pattern.\nsynonyms :\n'}


{'id': 'HP_0031666', 'url': 'http://purl.obolibrary.org/obo/HP_0031666', 'lbl': 'Late systolic murmur', 'desc': 'label: Late systolic murmur\ndefinition : A murmur that occurs in the latter phase of systole.\nsynonyms :\n'}


{'id': 'HP_0031667', 'url': 'http://purl.obolibrary.org/obo/HP_0031667', 'lbl': 'Holosystolic murmur', 'desc': 'label: Holosystolic murmur\ndefinition : A heart murmur that occurs during the entire systolic phase from S1 to S2.\nsynonyms :\n'}


{'id': 'HP_0031668', 'url': 'http://purl.obolibrary.org/obo/HP_0031668', 'lbl': 'Diastolic heart murmur', 'desc': 'label: Diastolic heart murmur\ndefinition : A heart murmur that occurs during diastole, i.e., in the time between S2 and the subsequent S1.\nsynonyms :\n'}


{'id': 'HP_0031669', 'url': 'http://purl.obolibrary.org/obo/HP_0031669', 'lbl': 'Middiastolic murmur', 'desc': 'label: Middiastolic murmur\ndefinition : A murmur that occurs in the middle of the diastolic phase.\nsynonyms :\n'}


{'id': 'HP_0031670', 'url': 'http://purl.obolibrary.org/obo/HP_0031670', 'lbl': 'Continuous heart murmur', 'desc': 'label: Continuous heart murmur\ndefinition : A murmur that occurs in both systole and diastole.\nsynonyms :\n'}


{'id': 'HP_0031671', 'url': 'http://purl.obolibrary.org/obo/HP_0031671', 'lbl': 'Typical atrial flutter', 'desc': "label: Typical atrial flutter\ndefinition : Typical atrial flutter is an organised atrial tachycardia. It can also be defined as a macroreentrant tachycardia confined to the right atrium. This arrhythmia has a 200-260 ms cycle length, although it may fluctuate depending on patient's previous treatment or ablation, congenital heart disease, etc. Ventricular rate response will be limited by the atrioventricular node conductions, usually presenting a 2:1 or 3:1 response, during atrial flutter. Typical (counter clockwise) flutter is associated with the common flutter pattern: a regular continuous undulation with dominant negative deflections in inferior leads II, III and aVF, often described also as a saw tooth pattern, and flat atrial deflections in leads I and aVL. Atrial deflections in V1 can be positive, biphasic or negative.\nsynonyms :\n"}


{'id': 'HP_0031672', 'url': 'http://purl.obolibrary.org/obo/HP_0031672', 'lbl': 'Reverse typical atrial flutter', 'desc': 'label: Reverse typical atrial flutter\ndefinition : A type of atrial flutter associated with rounded or bimodal positive deflections in inferior leads II, III and aVF, and a very characteristic bimodal negative wave in the shape of a W is seen in lead V1.\nsynonyms :\n'}


{'id': 'HP_0031673', 'url': 'http://purl.obolibrary.org/obo/HP_0031673', 'lbl': 'Orthodromic atrioventricular reentrant tachycardia', 'desc': 'label: Orthodromic atrioventricular reentrant tachycardia\ndefinition : A type of atrioventricular reentrant tachycardia (AVRT) where the atrioventricular node is used for anterograde conduction and the accessory pathway for retrograde conduction.\nsynonyms :Orthodromic AVRT\n'}


{'id': 'HP_0031674', 'url': 'http://purl.obolibrary.org/obo/HP_0031674', 'lbl': 'Antidromic atrioventricular reentrant tachycardia', 'desc': 'label: Antidromic atrioventricular reentrant tachycardia\ndefinition : A type of atrioventricular reentrant tachycardia (AVRT) where the accessory pathway is used for anterograde conduction and the atrioventricular node for retrograde conduction.\nsynonyms :Antidromic AVRT\n'}


{'id': 'HP_0031675', 'url': 'http://purl.obolibrary.org/obo/HP_0031675', 'lbl': 'Fascicular left ventricular tachycardia', 'desc': 'label: Fascicular left ventricular tachycardia\ndefinition : A ventricular tachycardia (VT) characterized by right bundle branch block (RBBB) and left axis deviation (LAD) on electrocardiogram (ECG).\nsynonyms :\n'}


{'id': 'HP_0031676', 'url': 'http://purl.obolibrary.org/obo/HP_0031676', 'lbl': 'Monomorphic ventricular tachycardia', 'desc': 'label: Monomorphic ventricular tachycardia\ndefinition : A type of ventricular tachycardia that is characterized by uniform QRS complexes within each lead (i.e., each QRS is identical or nearly so).\nsynonyms :\n'}


{'id': 'HP_0031677', 'url': 'http://purl.obolibrary.org/obo/HP_0031677', 'lbl': 'Polymorphic ventricular tachycardia', 'desc': 'label: Polymorphic ventricular tachycardia\ndefinition : A type of ventricular tachycardia that is characterized by variable QRS complexes within each lead (i.e., QRS complexes may be different from beat to beat).\nsynonyms :\n'}


{'id': 'HP_0031678', 'url': 'http://purl.obolibrary.org/obo/HP_0031678', 'lbl': 'Atherosclerotic lesion', 'desc': 'label: Atherosclerotic lesion\ndefinition : A lesion associated with atherosclerosis, a multifactorial and multipart progressive disease manifested by the focal development within the arterial wall of lesions, that ranges from teh development of a fatty streak, plaque progression, and plaque disruption. Atherosclerotic lesions demonstrate consistent morphological characteristics, which indicate that each type may stabilize temporarily or permanently and that progression to the next type may require an additional stimulus.\nsynonyms :\n'}


{'id': 'HP_0031679', 'url': 'http://purl.obolibrary.org/obo/HP_0031679', 'lbl': 'Type I atherosclerotic lesion', 'desc': 'label: Type I atherosclerotic lesion\ndefinition : Type I lesions represent the very initial changes and are recognized as an increase in the number of intimal macrophages and the appearance of macrophages filled with lipid droplets (foam cells).\nsynonyms :\n'}


{'id': 'HP_0031680', 'url': 'http://purl.obolibrary.org/obo/HP_0031680', 'lbl': 'Type II atherosclerotic lesion', 'desc': 'label: Type II atherosclerotic lesion\ndefinition : Type II atherosclerotic lesions include the fatty streak lesion, the first grossly visible lesion, and are characterized by layers of macrophage foam cells and lipid droplets within intimal smooth muscle cells and minimal coarse-grained particles and heterogeneous droplets of extracellular lipid.\nsynonyms :\n'}


{'id': 'HP_0031681', 'url': 'http://purl.obolibrary.org/obo/HP_0031681', 'lbl': 'Type III atherosclerotic lesion', 'desc': 'label: Type III atherosclerotic lesion\ndefinition : Type III (intermediate) atherosclerotic lesions are the morphological and chemical bridge between type II and advanced lesions. Type III lesions appear in some adaptive intimal thickenings (progression-prone locations) in young adults and are characterized by pools of extracellular lipid in addition to all the components of type II lesions.\nsynonyms :\n'}


{'id': 'HP_0031682', 'url': 'http://purl.obolibrary.org/obo/HP_0031682', 'lbl': 'Type V atherosclerotic lesion', 'desc': 'label: Type V atherosclerotic lesion\ndefinition : Type V lesions are defined as lesions in which prominent new fibrous connective tissue has formed. When the new tissue is part of a lesion with a lipid core (type IV), this type of morphology may be referred to as fibroatheroma or type Va lesion. A type V lesion in which the lipid core and other parts of the lesion are calcified may be referred to as type Vb. A type V lesion in which a lipid core is absent and lipid in general is minimal may be referred to as type Vc. With these lesions, arteries are variously narrowed, generally more than with type IV. Importantly, as with type IV lesions, type V lesions may develop fissures, hematoma, and/or thrombus (type VI lesion), and for this reason too they are clinically relevant.\nsynonyms :\n'}


{'id': 'HP_0031683', 'url': 'http://purl.obolibrary.org/obo/HP_0031683', 'lbl': 'Type VI atherosclerotic lesion', 'desc': 'label: Type VI atherosclerotic lesion\ndefinition : Type VI atherosclerotic lesions generally have the underlying morphology of type IV or V lesions, surface disruptions, hematoma, and thrombosis may be (although less often) superimposed on any other type of lesion and even on intima without an apparent lesion. Complicating features may arise because of individual differences in risk factors and tissue reactions. These may include differences in composition of the blood, the relative quantities and distributions in the components of the underlying lesion or intima, as well as modifications of shear and tensile forces to which the lesion or intima is exposed. Clinical imaging of lesions may be expected to contribute greatly to the understanding of type VI lesions and the associated clinical syndromes.\nsynonyms :\n'}


{'id': 'HP_0031684', 'url': 'http://purl.obolibrary.org/obo/HP_0031684', 'lbl': 'Renal artery atherosclerosis', 'desc': 'label: Renal artery atherosclerosis\ndefinition : An atherosclerotic lesion located in the renal artery.\nsynonyms :\n'}


{'id': 'HP_0031685', 'url': 'http://purl.obolibrary.org/obo/HP_0031685', 'lbl': 'Abnormal stool composition', 'desc': 'label: Abnormal stool composition\ndefinition : Abnormal level of metabolite or other abnormal analyte result in a stool test.\nsynonyms :Abnormal faeces composition; Abnormal feces composition; Abnormal fecal test result\n'}


{'id': 'HP_0031686', 'url': 'http://purl.obolibrary.org/obo/HP_0031686', 'lbl': 'Increased stool alpha1-antitrypsin concentration', 'desc': 'label: Increased stool alpha1-antitrypsin concentration\ndefinition : An abnormally elevated amount of alpha1-antitrypsin in the feces.\nsynonyms :\n'}


{'id': 'HP_0031687', 'url': 'http://purl.obolibrary.org/obo/HP_0031687', 'lbl': 'Abnormally loud pulmonic component of the second heart sound', 'desc': 'label: Abnormally loud pulmonic component of the second heart sound\ndefinition : \nsynonyms :Accentuation of the pulmonic component of the second heart sound\n'}


{'id': 'HP_0031688', 'url': 'http://purl.obolibrary.org/obo/HP_0031688', 'lbl': 'Erythroid dysplasia', 'desc': 'label: Erythroid dysplasia\ndefinition : Dysplasia in the erythroid lineage, which presents with a variety of morphological changes in the bone marrow, including nuclear budding or irregular nuclear contour in erythroblasts.\nsynonyms :\n'}


{'id': 'HP_0031689', 'url': 'http://purl.obolibrary.org/obo/HP_0031689', 'lbl': 'Megakaryocyte dysplasia', 'desc': 'label: Megakaryocyte dysplasia\ndefinition : The presence of micro-megakaryocytes, hypo-lobed, or non-lobed nuclei in megakaryocytes of all sizes and multiple, widely-separated nuclei.\nsynonyms :Dysmegakaryopoiesis\n'}


{'id': 'HP_0031690', 'url': 'http://purl.obolibrary.org/obo/HP_0031690', 'lbl': 'Opportunistic infection', 'desc': 'label: Opportunistic infection\ndefinition : An infection that is caused by a pathogen that would generally not be able to cause an infection in a host with a normal immune system. Such pathogens take advantage of the opportunity, so to speak, that is provided by a weakened immune system.\nsynonyms :\n'}


{'id': 'HP_0031691', 'url': 'http://purl.obolibrary.org/obo/HP_0031691', 'lbl': 'Severe viral infection', 'desc': 'label: Severe viral infection\ndefinition : An unusually severe viral infection.\nsynonyms :\n'}


{'id': 'HP_0031692', 'url': 'http://purl.obolibrary.org/obo/HP_0031692', 'lbl': 'Severe cytomegalovirus infection', 'desc': 'label: Severe cytomegalovirus infection\ndefinition : An unusually severe infection by cytomegalovirus.\nsynonyms :\n'}


{'id': 'HP_0031693', 'url': 'http://purl.obolibrary.org/obo/HP_0031693', 'lbl': 'Severe Epstein Barr virus infection', 'desc': 'label: Severe Epstein Barr virus infection\ndefinition : An unusually severe Epstein Barr virus (EBV) infection.\nsynonyms :Fulminant infectious mononucleosis; Severe EBV infection\n'}


{'id': 'HP_0031694', 'url': 'http://purl.obolibrary.org/obo/HP_0031694', 'lbl': 'Severe adenovirus infection', 'desc': 'label: Severe adenovirus infection\ndefinition : An unusually severe adenovirus infection.\nsynonyms :\n'}


{'id': 'HP_0031695', 'url': 'http://purl.obolibrary.org/obo/HP_0031695', 'lbl': 'Severe parainfluenza infection', 'desc': 'label: Severe parainfluenza infection\ndefinition : An unusually severe infection by a parainfluenza virus.\nsynonyms :\n'}


{'id': 'HP_0031696', 'url': 'http://purl.obolibrary.org/obo/HP_0031696', 'lbl': 'Disseminated viral infection', 'desc': 'label: Disseminated viral infection\ndefinition : A viral infection that fails to be contained by the immune sytem and spreads throughout the body.\nsynonyms :\n'}


{'id': 'HP_0031697', 'url': 'http://purl.obolibrary.org/obo/HP_0031697', 'lbl': 'Disseminated infection with live vaccine virus', 'desc': 'label: Disseminated infection with live vaccine virus\ndefinition : A dissemination viral infection caused by a live attenuated vaccine virus.\nsynonyms :\n'}


{'id': 'HP_0031698', 'url': 'http://purl.obolibrary.org/obo/HP_0031698', 'lbl': 'obsolete Disseminated Bacillus Calmette-Guerin infection', 'desc': 'label: obsolete Disseminated Bacillus Calmette-Guerin infection\ndefinition : Failure to contain thebacillus Calmette-Guerin (BCG) following vaccination leading to spread of BCG to many sites in the body. The tuberculosis vaccine BCG contains live attenuated Mycobacterium bovis.\nsynonyms :\n'}


{'id': 'HP_0031699', 'url': 'http://purl.obolibrary.org/obo/HP_0031699', 'lbl': 'Disseminated cryptosporidium infection', 'desc': 'label: Disseminated cryptosporidium infection\ndefinition : Failure to contain infection by a protozoan of the genus Cryptosporidium, leading to spread to many parts of the body.\nsynonyms :\n'}


{'id': 'HP_0031700', 'url': 'http://purl.obolibrary.org/obo/HP_0031700', 'lbl': 'Invasive parasitic infection', 'desc': 'label: Invasive parasitic infection\ndefinition : A parasitic infection whereby the parasite invades (migrates through) tissues of the infected host.\nsynonyms :\n'}


{'id': 'HP_0031701', 'url': 'http://purl.obolibrary.org/obo/HP_0031701', 'lbl': 'Anterior chamber inflammatory cells', 'desc': 'label: Anterior chamber inflammatory cells\ndefinition : The presence of inflammatory cells in the aqueous humor of the anterior chamber of the eye.\nsynonyms :\n'}


{'id': 'HP_0031702', 'url': 'http://purl.obolibrary.org/obo/HP_0031702', 'lbl': 'Anterior chamber red blood cells', 'desc': 'label: Anterior chamber red blood cells\ndefinition : The presence of erythrocyte in the aqueous humor of the anterior chamber of the eye.\nsynonyms :Anterior chamber RBCs\n'}


{'id': 'HP_0031703', 'url': 'http://purl.obolibrary.org/obo/HP_0031703', 'lbl': 'Abnormal ear morphology', 'desc': 'label: Abnormal ear morphology\ndefinition : Any structural anomaly of the ear.\nsynonyms :\n'}


{'id': 'HP_0031704', 'url': 'http://purl.obolibrary.org/obo/HP_0031704', 'lbl': 'Abnormal ear physiology', 'desc': 'label: Abnormal ear physiology\ndefinition : Any functional anomaly of the ear.\nsynonyms :\n'}


{'id': 'HP_0031705', 'url': 'http://purl.obolibrary.org/obo/HP_0031705', 'lbl': 'Compensatory head posture', 'desc': 'label: Compensatory head posture\ndefinition : A compensatory head posture occurs when the head is deviated out of the normal primary straight head position in order to compensate for an ocular problem.\nsynonyms :\n'}


{'id': 'HP_0031706', 'url': 'http://purl.obolibrary.org/obo/HP_0031706', 'lbl': 'Compensatory chin depression', 'desc': 'label: Compensatory chin depression\ndefinition : A tendency to hold the chin depressed (lowered) to compensate for a limitation of eye movement.\nsynonyms :\n'}


{'id': 'HP_0031707', 'url': 'http://purl.obolibrary.org/obo/HP_0031707', 'lbl': 'Compensatory face turn to the right', 'desc': 'label: Compensatory face turn to the right\ndefinition : A tendency to turn the face to the right to compensate for a limitation of eye movement.\nsynonyms :\n'}


{'id': 'HP_0031708', 'url': 'http://purl.obolibrary.org/obo/HP_0031708', 'lbl': 'Compensatory face turn to the left', 'desc': 'label: Compensatory face turn to the left\ndefinition : A tendency to turn the face to the left to compensate for a limitation of eye movement.\nsynonyms :\n'}


{'id': 'HP_0031709', 'url': 'http://purl.obolibrary.org/obo/HP_0031709', 'lbl': 'Compensatory head tilt to the right shoulder', 'desc': 'label: Compensatory head tilt to the right shoulder\ndefinition : A tendency to tilt the head towards the right shoulder to compensate for a limitation of eye movement.\nsynonyms :\n'}


{'id': 'HP_0031710', 'url': 'http://purl.obolibrary.org/obo/HP_0031710', 'lbl': 'Compensatory head tilt to the left shoulder', 'desc': 'label: Compensatory head tilt to the left shoulder\ndefinition : A tendency to tilt the head towards the left shoulder to compensate for a limitation of eye movement.\nsynonyms :\n'}


{'id': 'HP_0031711', 'url': 'http://purl.obolibrary.org/obo/HP_0031711', 'lbl': 'Asymmetric abdominal aortic aneurysm', 'desc': 'label: Asymmetric abdominal aortic aneurysm\ndefinition : An abdominal aortic aneurysm that is not symmetric around its axis (not axisymmetric).\nsynonyms :\n'}


{'id': 'HP_0031713', 'url': 'http://purl.obolibrary.org/obo/HP_0031713', 'lbl': 'Constant exotropia', 'desc': 'label: Constant exotropia\ndefinition : A form of divergent strabismus (exotropia) in which the eye turns outward at all distances and at all times.\nsynonyms :\n'}


{'id': 'HP_0031714', 'url': 'http://purl.obolibrary.org/obo/HP_0031714', 'lbl': 'Distance exotropia', 'desc': 'label: Distance exotropia\ndefinition : A type of divergent strabismus (exotropia) in which an eye tends to turn outwards (i.e., the eye squints) mainly when looking at distant objects. The eyes tend to remain straight when they look at near objects. Distance exotropia may be constant or intermittent.\nsynonyms :\n'}


{'id': 'HP_0031715', 'url': 'http://purl.obolibrary.org/obo/HP_0031715', 'lbl': 'Near exotropia', 'desc': 'label: Near exotropia\ndefinition : An intermittent exotropia where there is binocular single vision on distance fixation and exotropia at near (intermittent or constant).\nsynonyms :\n'}


{'id': 'HP_0031716', 'url': 'http://purl.obolibrary.org/obo/HP_0031716', 'lbl': 'Cyclic exotropia', 'desc': 'label: Cyclic exotropia\ndefinition : A type of exotropia (divergent strabismus) in which binocular single vision alternates with large angle exotropia in rhythmic cycle.\nsynonyms :\n'}


{'id': 'HP_0031717', 'url': 'http://purl.obolibrary.org/obo/HP_0031717', 'lbl': 'Alternating exotropia', 'desc': 'label: Alternating exotropia\ndefinition : A type of exotropia in which either eye may be used for fixation.\nsynonyms :Alternating strabismus\n'}


{'id': 'HP_0031718', 'url': 'http://purl.obolibrary.org/obo/HP_0031718', 'lbl': 'Consecutive exotropia', 'desc': 'label: Consecutive exotropia\ndefinition : Exotropia in an individual who has previously had esotropia or esophoria.\nsynonyms :\n'}


{'id': 'HP_0031719', 'url': 'http://purl.obolibrary.org/obo/HP_0031719', 'lbl': 'True distance exotropia', 'desc': 'label: True distance exotropia\ndefinition : Exotropia (intermittent or constant) on distance fixation with binocular single vision on near fixation under all testing conditions. The accommodative convergence/accommodation (AC:A) ratio is within normal limits.\nsynonyms :\n'}


{'id': 'HP_0031720', 'url': 'http://purl.obolibrary.org/obo/HP_0031720', 'lbl': 'Simulated distance exotropia', 'desc': 'label: Simulated distance exotropia\ndefinition : Exotropia (intermittent or constant) worse for distance fixation in which the near angle of deviation increases (or near exophoria becomes exotropia) with: (1) prolonged disruption of fusion and/or (2) elimination of accommodation.\nsynonyms :\n'}


{'id': 'HP_0031721', 'url': 'http://purl.obolibrary.org/obo/HP_0031721', 'lbl': 'Sensory exotropia', 'desc': 'label: Sensory exotropia\ndefinition : A type of divergent strabismus (exotropia) that develops in a poorly seeing eye.\nsynonyms :Secondary exotropia\n'}


{'id': 'HP_0031722', 'url': 'http://purl.obolibrary.org/obo/HP_0031722', 'lbl': 'Near esotropia', 'desc': 'label: Near esotropia\ndefinition : An intermittent esotropia where there is binocular single vision on distance fixation and esotropia at near even when the accommodation is relieved.\nsynonyms :Non-accomodative convergence excess esotropia\n'}


{'id': 'HP_0031723', 'url': 'http://purl.obolibrary.org/obo/HP_0031723', 'lbl': 'Secondary esotropia', 'desc': 'label: Secondary esotropia\ndefinition : Convergent squint which follows loss or impairment of vision.\nsynonyms :Sensory esotropia\n'}


{'id': 'HP_0031724', 'url': 'http://purl.obolibrary.org/obo/HP_0031724', 'lbl': 'Microtropia', 'desc': 'label: Microtropia\ndefinition : A small angle heterotropia (usually of 10 diopters or less) in which a form of binocular single vision occurs.\nsynonyms :\n'}


{'id': 'HP_0031725', 'url': 'http://purl.obolibrary.org/obo/HP_0031725', 'lbl': 'Hypophoria', 'desc': 'label: Hypophoria\ndefinition : A form of latent strabismus (heterophoria) in which, on dissociation, the occluded eye deviates downwards.\nsynonyms :\n'}


{'id': 'HP_0031726', 'url': 'http://purl.obolibrary.org/obo/HP_0031726', 'lbl': 'Incyclotropia', 'desc': 'label: Incyclotropia\ndefinition : A type of cyclotropia (torsion of one or both eye around the visual axis of the eyes) in which the upper poles of the globes are rotated inward (medially) to each other.\nsynonyms :\n'}


{'id': 'HP_0031727', 'url': 'http://purl.obolibrary.org/obo/HP_0031727', 'lbl': 'Excyclotropia', 'desc': 'label: Excyclotropia\ndefinition : A type of cyclotropia (torsion of one or both eye around the visual axis of the eyes) in which the upper poles of the globes are rotated outward (laterally) to each other.\nsynonyms :\n'}


{'id': 'HP_0031728', 'url': 'http://purl.obolibrary.org/obo/HP_0031728', 'lbl': 'Mild hypermetropia', 'desc': 'label: Mild hypermetropia\ndefinition : A form of hypermetropia with not more than +2.00 diopters.\nsynonyms :Mild hyperopia\n'}


{'id': 'HP_0031729', 'url': 'http://purl.obolibrary.org/obo/HP_0031729', 'lbl': 'Moderate hypermetropia', 'desc': 'label: Moderate hypermetropia\ndefinition : A form of hypermetropia with more than +2.00 diopters but not more than +5.00 diopters.\nsynonyms :Moderate hyperopia\n'}


{'id': 'HP_0031730', 'url': 'http://purl.obolibrary.org/obo/HP_0031730', 'lbl': 'Axial myopia', 'desc': 'label: Axial myopia\ndefinition : A form of myopia related to an axial length above the norm and too long for the refractive power of the whole optical system of the eye.\nsynonyms :\n'}


{'id': 'HP_0031731', 'url': 'http://purl.obolibrary.org/obo/HP_0031731', 'lbl': 'Increased tear production', 'desc': 'label: Increased tear production\ndefinition : Increased lacrimation owing to overproduction of tears.\nsynonyms :\n'}


{'id': 'HP_0031732', 'url': 'http://purl.obolibrary.org/obo/HP_0031732', 'lbl': 'Increased basal tear production', 'desc': 'label: Increased basal tear production\ndefinition : A form of watery eye associated with overproduction of tears due to an increased parasympathetic drive to the secretory component of the lacrimal system (lacrimal gland); this could be due to pro-secretory drug use (e.g. pilocarpine) or autonomic disturbance.\nsynonyms :\n'}


{'id': 'HP_0031733', 'url': 'http://purl.obolibrary.org/obo/HP_0031733', 'lbl': 'Reflex tearing', 'desc': 'label: Reflex tearing\ndefinition : A form of watery eye associated with overproduction of tears due to reflex tearing in response to a local irritant (e.g. trichiasis or foreign body), chronic ocular surface disease (e.g. blepharitis) or systemic disease (e.g. thyroid eye disease).\nsynonyms :\n'}


{'id': 'HP_0031734', 'url': 'http://purl.obolibrary.org/obo/HP_0031734', 'lbl': 'Lacrimal pump failure', 'desc': 'label: Lacrimal pump failure\ndefinition : A form of watery eye associated with abnormal lid tone and/or lid position. The former is due to lid laxity (common involutional change in the elderly) or a weak orbicularis muscle (e.g. due to VII cranial nerve palsy). The latter is typically associated with ectropion causing punctal eversion.\nsynonyms :\n'}


{'id': 'HP_0031736', 'url': 'http://purl.obolibrary.org/obo/HP_0031736', 'lbl': 'Involutional entropion', 'desc': 'label: Involutional entropion\ndefinition : An abnormal inversion of the eyelid towards the globe resulting from inferior retractor muscle dysfunction with tissue laxity and, possibly, overriding of the preseptal orbicularis muscle over the pretarsal orbicularis muscle.\nsynonyms :\n'}


{'id': 'HP_0031737', 'url': 'http://purl.obolibrary.org/obo/HP_0031737', 'lbl': 'Cicatricial entropion', 'desc': 'label: Cicatricial entropion\ndefinition : Abnormal inversion (turning inward) of the eyelid towards the globe associated with scarring that vertically shortens the posterior lamella of the eyelid.\nsynonyms :\n'}


{'id': 'HP_0031738', 'url': 'http://purl.obolibrary.org/obo/HP_0031738', 'lbl': 'Mechanical entropion', 'desc': 'label: Mechanical entropion\ndefinition : A type of entropion (abnormal inversion of the eyelid towards the globe) that is related to a mass effect of a lesion (e.g., a tumor) that pulls the eyelid margin away from the globe.\nsynonyms :\n'}


{'id': 'HP_0031739', 'url': 'http://purl.obolibrary.org/obo/HP_0031739', 'lbl': 'Abnormal oblique muscle physiology', 'desc': 'label: Abnormal oblique muscle physiology\ndefinition : A functional anomaly of the inferior or superior oblique muscle.\nsynonyms :\n'}


{'id': 'HP_0031740', 'url': 'http://purl.obolibrary.org/obo/HP_0031740', 'lbl': 'Abnormal horizontal rectus muscle physiology', 'desc': 'label: Abnormal horizontal rectus muscle physiology\ndefinition : A functional anomaly of the medial rectus muscle or lateral rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031741', 'url': 'http://purl.obolibrary.org/obo/HP_0031741', 'lbl': 'Inferior oblique muscle underaction', 'desc': 'label: Inferior oblique muscle underaction\ndefinition : Reduced ocular movement by the inferior oblique muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :\n'}


{'id': 'HP_0031742', 'url': 'http://purl.obolibrary.org/obo/HP_0031742', 'lbl': 'Inferior rectus muscle underaction', 'desc': 'label: Inferior rectus muscle underaction\ndefinition : Reduced movement by the inferior rectus muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :\n'}


{'id': 'HP_0031743', 'url': 'http://purl.obolibrary.org/obo/HP_0031743', 'lbl': 'Inferior rectus muscle overaction', 'desc': 'label: Inferior rectus muscle overaction\ndefinition : Excessive action of the inferior rectus muscle caused by increased innervation typically as a consequence of palsy or limitation to the ipsilateral antagonist or contralateral synergist.\nsynonyms :\n'}


{'id': 'HP_0031744', 'url': 'http://purl.obolibrary.org/obo/HP_0031744', 'lbl': 'Superior rectus muscle weakness', 'desc': 'label: Superior rectus muscle weakness\ndefinition : Decreased strength of the superior rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031745', 'url': 'http://purl.obolibrary.org/obo/HP_0031745', 'lbl': 'Superior rectus muscle overaction', 'desc': 'label: Superior rectus muscle overaction\ndefinition : Excessive action of the superior rectus muscle caused by increased innervation typically as a consequence of palsy or limitation to the ipsilateral antagonist or contralateral synergist.\nsynonyms :\n'}


{'id': 'HP_0031746', 'url': 'http://purl.obolibrary.org/obo/HP_0031746', 'lbl': 'Superior rectus muscle restriction', 'desc': 'label: Superior rectus muscle restriction\ndefinition : Mechanical limitation of the range of movement of the superior rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031747', 'url': 'http://purl.obolibrary.org/obo/HP_0031747', 'lbl': 'Superior rectus muscle underaction', 'desc': 'label: Superior rectus muscle underaction\ndefinition : Reduced movement of the superior rectus muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :\n'}


{'id': 'HP_0031748', 'url': 'http://purl.obolibrary.org/obo/HP_0031748', 'lbl': 'Abnormal vertical rectus muscle physiology', 'desc': 'label: Abnormal vertical rectus muscle physiology\ndefinition : A functional anomaly of the superior or inferior rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031749', 'url': 'http://purl.obolibrary.org/obo/HP_0031749', 'lbl': 'Abnormal lateral rectus muscle physiology', 'desc': 'label: Abnormal lateral rectus muscle physiology\ndefinition : A functional anomaly of the lateral rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031750', 'url': 'http://purl.obolibrary.org/obo/HP_0031750', 'lbl': 'Lateral rectus muscle weakness', 'desc': 'label: Lateral rectus muscle weakness\ndefinition : Decreased strength (ability to move) of the lateral rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031751', 'url': 'http://purl.obolibrary.org/obo/HP_0031751', 'lbl': 'Lateral rectus muscle underaction', 'desc': 'label: Lateral rectus muscle underaction\ndefinition : Reduced movement of the lateral rectus muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :\n'}


{'id': 'HP_0031752', 'url': 'http://purl.obolibrary.org/obo/HP_0031752', 'lbl': 'Lateral rectus muscle overaction', 'desc': 'label: Lateral rectus muscle overaction\ndefinition : Excessive action of the lateral rectus muscle caused by increased innervation typically as a consequence of palsy or limitation to the ipsilateral antagonist or contralateral synergist.\nsynonyms :\n'}


{'id': 'HP_0031753', 'url': 'http://purl.obolibrary.org/obo/HP_0031753', 'lbl': 'Medial rectus muscle weakness', 'desc': 'label: Medial rectus muscle weakness\ndefinition : Decreased strength of the medial rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031754', 'url': 'http://purl.obolibrary.org/obo/HP_0031754', 'lbl': 'Medial rectus muscle overaction', 'desc': 'label: Medial rectus muscle overaction\ndefinition : Excessive action of the medial rectus muscle caused by increased innervation typically as a consequence of palsy or limitation to the ipsilateral antagonist or contralateral synergist.\nsynonyms :\n'}


{'id': 'HP_0031755', 'url': 'http://purl.obolibrary.org/obo/HP_0031755', 'lbl': 'Abnormal rectus muscle physiology', 'desc': 'label: Abnormal rectus muscle physiology\ndefinition : A functional anomaly of a vertical or horizontal rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031756', 'url': 'http://purl.obolibrary.org/obo/HP_0031756', 'lbl': 'Medial rectus muscle underaction', 'desc': 'label: Medial rectus muscle underaction\ndefinition : Reduced movement of the medial rectus muscle which improves on testing ductions, typically associated with neurogenic palsy.\nsynonyms :\n'}


{'id': 'HP_0031757', 'url': 'http://purl.obolibrary.org/obo/HP_0031757', 'lbl': 'Medial rectus muscle restriction', 'desc': 'label: Medial rectus muscle restriction\ndefinition : Mechanical limitation of the range of movement of the medial rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031758', 'url': 'http://purl.obolibrary.org/obo/HP_0031758', 'lbl': 'Lateral rectus muscle restriction', 'desc': 'label: Lateral rectus muscle restriction\ndefinition : Mechanical limitation of the range of movement of the lateral rectus muscle.\nsynonyms :\n'}


{'id': 'HP_0031759', 'url': 'http://purl.obolibrary.org/obo/HP_0031759', 'lbl': 'Basic constant esotropia', 'desc': 'label: Basic constant esotropia\ndefinition : A form of convergent strabismus (esotropia) in which the deviation is present under all conditions (ie at all distances and at all times).\nsynonyms :Basic (constant) esotropia\n'}


{'id': 'HP_0031760', 'url': 'http://purl.obolibrary.org/obo/HP_0031760', 'lbl': 'Non-accomodative esotropia', 'desc': 'label: Non-accomodative esotropia\ndefinition : A form of esotropia in which the angle of deviation is not affected by accommodative effort.\nsynonyms :\n'}


{'id': 'HP_0031761', 'url': 'http://purl.obolibrary.org/obo/HP_0031761', 'lbl': 'Infantile constant esotropia', 'desc': 'label: Infantile constant esotropia\ndefinition : Constant esotropia occurring before 6 months of age. It is typically associated with a large angle of deviation, alternating fixation (therefore low risk of amblyopia) and poor potential for binocular single vision. Other features that might be present in individuals with infantile (constant) esotropia include latent nystagmus or manifest latent nystagmus, dissociated vertical divergence, cyclotropia, abnormal head posture, limited abduction.\nsynonyms :Infantile (constant) esotropia\n'}


{'id': 'HP_0031762', 'url': 'http://purl.obolibrary.org/obo/HP_0031762', 'lbl': 'Distance esotropia', 'desc': 'label: Distance esotropia\ndefinition : An intermittent esotropia where binocular single vision is present on near fixation and an esotropia on distance fixation. Often associated with myopia and aging.\nsynonyms :Divergence insufficiency\n'}


{'id': 'HP_0031763', 'url': 'http://purl.obolibrary.org/obo/HP_0031763', 'lbl': 'Cyclic esotropia', 'desc': 'label: Cyclic esotropia\ndefinition : Convergent strabismus in which normal binocular single vision is alternating with large angle esotropia in rhythmic cycle.\nsynonyms :\n'}


{'id': 'HP_0031764', 'url': 'http://purl.obolibrary.org/obo/HP_0031764', 'lbl': 'Fully accomodative esotropia', 'desc': 'label: Fully accomodative esotropia\ndefinition : Esotropia in which normal binocular single vision is present for all distances when the hypermetropic refractive error is corrected. Esotropia is present for near and distance on accommodation without correction.\nsynonyms :\n'}


{'id': 'HP_0031765', 'url': 'http://purl.obolibrary.org/obo/HP_0031765', 'lbl': 'Partially accomodative esotropia', 'desc': 'label: Partially accomodative esotropia\ndefinition : A form of constant esotropia in which the angle of deviation is partially affected by accommodative effort. Typically there is esotropia at near and distance with hypermetropic correction and the angle of deviation increases without glasses.\nsynonyms :Constant esotropia with an accommodative component; Constant esotropia with an accommodative element\n'}


{'id': 'HP_0031766', 'url': 'http://purl.obolibrary.org/obo/HP_0031766', 'lbl': 'Convergence excess esotropia', 'desc': 'label: Convergence excess esotropia\ndefinition : An intermittent esotropia with binocular single vision present at distance fixation but esotropia on accommodation for near fixation. Usually associated with hypermetropia but patients can be emmetropic and rarely myopic. Associated with a high accommodative convergence/accommodation (AC/A) ratio.\nsynonyms :\n'}


{'id': 'HP_0031767', 'url': 'http://purl.obolibrary.org/obo/HP_0031767', 'lbl': 'Consecutive esotropia', 'desc': 'label: Consecutive esotropia\ndefinition : Esotropia in a patient who has previously had exotropia or exophoria; may be constant or intermittent and usually follows surgical overcorrection.\nsynonyms :\n'}


{'id': 'HP_0031768', 'url': 'http://purl.obolibrary.org/obo/HP_0031768', 'lbl': 'Parafoveal fixation', 'desc': 'label: Parafoveal fixation\ndefinition : Fixation of an object in the area adjacent to the fovea.\nsynonyms :\n'}


{'id': 'HP_0031769', 'url': 'http://purl.obolibrary.org/obo/HP_0031769', 'lbl': 'Peripheral fixation', 'desc': 'label: Peripheral fixation\ndefinition : Fixation of an object in a peripheral area of the retina.\nsynonyms :\n'}


{'id': 'HP_0031770', 'url': 'http://purl.obolibrary.org/obo/HP_0031770', 'lbl': 'Epicanthus palpebralis', 'desc': 'label: Epicanthus palpebralis\ndefinition : A type of epicanthus in which a medial vertical fold is present between upper and lower lids.\nsynonyms :\n'}


{'id': 'HP_0031771', 'url': 'http://purl.obolibrary.org/obo/HP_0031771', 'lbl': 'Epicanthus tarsalis', 'desc': 'label: Epicanthus tarsalis\ndefinition : A type of epicanthus in which a primarily upper lid fold is present.\nsynonyms :\n'}


{'id': 'HP_0031772', 'url': 'http://purl.obolibrary.org/obo/HP_0031772', 'lbl': 'Abnormal posterior circulating artery morphology', 'desc': 'label: Abnormal posterior circulating artery morphology\ndefinition : Any structural anomaly of the posterior circulating artery (PCOM).\nsynonyms :\n'}


{'id': 'HP_0031773', 'url': 'http://purl.obolibrary.org/obo/HP_0031773', 'lbl': 'Posterior communicating artery aneurysm', 'desc': 'label: Posterior communicating artery aneurysm\ndefinition : A widening (ballooning) localized in the wall of the posterior communicating artery.\nsynonyms :\n'}


{'id': 'HP_0031774', 'url': 'http://purl.obolibrary.org/obo/HP_0031774', 'lbl': 'Posterior communicating artery infundibulum', 'desc': 'label: Posterior communicating artery infundibulum\ndefinition : A funnel-shaped symmetrical enlargement of the origin of the posterior communicating artery at its junction with the internal carotid artery.\nsynonyms :\n'}


{'id': 'HP_0031775', 'url': 'http://purl.obolibrary.org/obo/HP_0031775', 'lbl': 'Neurogenic strabismus', 'desc': 'label: Neurogenic strabismus\ndefinition : An ocular deviation caused by a palsy to one or more of the extraocular muscles or nerves supplying them.\nsynonyms :Paralytic strabismus\n'}


{'id': 'HP_0031776', 'url': 'http://purl.obolibrary.org/obo/HP_0031776', 'lbl': 'Cyclotropia', 'desc': 'label: Cyclotropia\ndefinition : A form of manifest strabismus (heterotropia) in which the one eye is wheel rotated so that the upper end of its vertical axis is nasal (incyclotropia) or temporal (excyclotropia).\nsynonyms :\n'}


{'id': 'HP_0031777', 'url': 'http://purl.obolibrary.org/obo/HP_0031777', 'lbl': 'Cyclophoria', 'desc': 'label: Cyclophoria\ndefinition : A form of latent strabismus (heterophoria) in which the occluded eye wheel-rotates on dissociation.\nsynonyms :\n'}


{'id': 'HP_0031778', 'url': 'http://purl.obolibrary.org/obo/HP_0031778', 'lbl': 'Incyclophoria', 'desc': 'label: Incyclophoria\ndefinition : A type of cyclophoria (latent strabismus in which the occluded eye wheel-rotates on dissociation.) in which the upper poles of the globes are rotated inward (medially) to each other.\nsynonyms :\n'}


{'id': 'HP_0031779', 'url': 'http://purl.obolibrary.org/obo/HP_0031779', 'lbl': 'Excyclophoria', 'desc': 'label: Excyclophoria\ndefinition : A type of cyclophoria (latent strabismus in which the occluded eye wheel-rotates on dissociation.) in which the upper poles of the globes are rotated outward (laterally) to each other.\nsynonyms :\n'}


{'id': 'HP_0031780', 'url': 'http://purl.obolibrary.org/obo/HP_0031780', 'lbl': 'Eosinophilic ascites', 'desc': 'label: Eosinophilic ascites\ndefinition : A type of ascites in which there are large numbers of eosinophils in the ascitis fluid.\nsynonyms :\n'}


{'id': 'HP_0031781', 'url': 'http://purl.obolibrary.org/obo/HP_0031781', 'lbl': 'Microtropia with identity', 'desc': 'label: Microtropia with identity\ndefinition : A type of microtropia with no manifest movement on cover test, the eccentric fixation point coinciding with the angle of ARC.\nsynonyms :\n'}


{'id': 'HP_0031782', 'url': 'http://purl.obolibrary.org/obo/HP_0031782', 'lbl': 'Microtropia without identity', 'desc': 'label: Microtropia without identity\ndefinition : A type of microtropia in which the manifest movement is demonstrated on the cover-uncover test.\nsynonyms :\n'}


{'id': 'HP_0031783', 'url': 'http://purl.obolibrary.org/obo/HP_0031783', 'lbl': 'Absent coronary sinus', 'desc': 'label: Absent coronary sinus\ndefinition : A developmental defect in which the coronary sinus fails to form.\nsynonyms :\n'}


{'id': 'HP_0031784', 'url': 'http://purl.obolibrary.org/obo/HP_0031784', 'lbl': 'Abnormal ascending aorta morphology', 'desc': 'label: Abnormal ascending aorta morphology\ndefinition : Any structural anomaly of the portion of the aorta that arises from the base of the left ventricle and extends upward to the aortic arch and from which the coronary arteries arise.\nsynonyms :\n'}


{'id': 'HP_0031785', 'url': 'http://purl.obolibrary.org/obo/HP_0031785', 'lbl': 'Abnormal eyelid movement', 'desc': 'label: Abnormal eyelid movement\ndefinition : An abnormality in voluntary or involuntary eyelid movements or their control.\nsynonyms :\n'}


{'id': 'HP_0031786', 'url': 'http://purl.obolibrary.org/obo/HP_0031786', 'lbl': 'Cogan lid twitch', 'desc': 'label: Cogan lid twitch\ndefinition : Transient eyelid retraction during refixation from down to straight ahead.\nsynonyms :Cogan eyelid twitch; Eyelid twitch; Lid twitch\n'}


{'id': 'HP_0031787', 'url': 'http://purl.obolibrary.org/obo/HP_0031787', 'lbl': 'Oblique astigmatism', 'desc': 'label: Oblique astigmatism\ndefinition : Astigmatism in which the refractive power of the vertical meridian is the greatest.\nsynonyms :\n'}


{'id': 'HP_0031788', 'url': 'http://purl.obolibrary.org/obo/HP_0031788', 'lbl': 'With the rule astigmatism', 'desc': 'label: With the rule astigmatism\ndefinition : Refractive error in which the vertical meridian is relatively hypermetropic and the horizontal meridian is relatively myopic (or ocular astigmatism in which the refractive power of the horizontal meridian is the greatest).\nsynonyms :\n'}


{'id': 'HP_0031789', 'url': 'http://purl.obolibrary.org/obo/HP_0031789', 'lbl': 'Against the rule astigmatism', 'desc': 'label: Against the rule astigmatism\ndefinition : Astigmatism with more plus power on the horizontal meridian.\nsynonyms :\n'}


{'id': 'HP_0031790', 'url': 'http://purl.obolibrary.org/obo/HP_0031790', 'lbl': 'Mixed astigmatism', 'desc': 'label: Mixed astigmatism\ndefinition : A type of astigmatism in which an unequal curvature of the cornea and some cases additionally of the lens causes one meridian of the eye to be hyperopic (farsighted) and a second meridian that is perpendicular to the first to be myopic (nearsighted).\nsynonyms :\n'}


{'id': 'HP_0031791', 'url': 'http://purl.obolibrary.org/obo/HP_0031791', 'lbl': 'Lenticular astigmatism', 'desc': 'label: Lenticular astigmatism\ndefinition : A type of astigmatism related to an irregular shape of the lens.\nsynonyms :\n'}


{'id': 'HP_0031792', 'url': 'http://purl.obolibrary.org/obo/HP_0031792', 'lbl': 'Irregular astigmatism', 'desc': 'label: Irregular astigmatism\ndefinition : A type of astigmatism in which the principle meridians are not 90 degrees apart and which is associated with loss of vision.\nsynonyms :\n'}


{'id': 'HP_0031793', 'url': 'http://purl.obolibrary.org/obo/HP_0031793', 'lbl': 'Increased serum leptin', 'desc': 'label: Increased serum leptin\ndefinition : An increased concentration of leptin in the blood.\nsynonyms :Elevated circulating leptin level\n'}


{'id': 'HP_0031794', 'url': 'http://purl.obolibrary.org/obo/HP_0031794', 'lbl': 'Decreased circulating glycerol level', 'desc': 'label: Decreased circulating glycerol level\ndefinition : A decrease below the normal concentration of glycerol in the blood.\nsynonyms :\n'}


{'id': 'HP_0031795', 'url': 'http://purl.obolibrary.org/obo/HP_0031795', 'lbl': 'Abnormal circulating glycerol level', 'desc': 'label: Abnormal circulating glycerol level\ndefinition : Any deviation from the normal concentration of glycerol in the blood.\nsynonyms :\n'}


{'id': 'HP_0031796', 'url': 'http://purl.obolibrary.org/obo/HP_0031796', 'lbl': 'Recurrent', 'desc': 'label: Recurrent\ndefinition : Applies to a sign, symptom or manifestation that occurs multiple times separated by intervals in which the sign, symptom, or manifestation is not present.\nsynonyms :Intermittent\n'}


{'id': 'HP_0031797', 'url': 'http://purl.obolibrary.org/obo/HP_0031797', 'lbl': 'Clinical course', 'desc': 'label: Clinical course\ndefinition : The course a disease typically takes from its onset, progression in time, and eventual resolution or death of the affected individual.\nsynonyms :Natural history of disease\n'}


{'id': 'HP_0031798', 'url': 'http://purl.obolibrary.org/obo/HP_0031798', 'lbl': 'Elevated circulating apolipoprotein B concentration', 'desc': 'label: Elevated circulating apolipoprotein B concentration\ndefinition : Increased circulating level of apolipoprotein B, which is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100.\nsynonyms :Elevated ApoB level; Elevated apolipoprotein B level\n'}


{'id': 'HP_0031799', 'url': 'http://purl.obolibrary.org/obo/HP_0031799', 'lbl': 'Decreased circulating apolipoprotein A-I concentration', 'desc': 'label: Decreased circulating apolipoprotein A-I concentration\ndefinition : Concentration of apolipoprotein A-I below the lower limit of normal. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma. Defects in this gene are associated with HDL deficiencies, including Tangier disease.\nsynonyms :Decreased apo-AI level; Decreased apoA-I level; Decreased apolipoprotein AI level\n'}


{'id': 'HP_0031800', 'url': 'http://purl.obolibrary.org/obo/HP_0031800', 'lbl': 'Elevated circulating apolipoprotein A-II concentration', 'desc': 'label: Elevated circulating apolipoprotein A-II concentration\ndefinition : An increased concentration in blood of apolipoprotein A-II, a major component of HDL particles, associated with triglyceride and glucose metabolism.\nsynonyms :Elevated APOAII level; Elevated Apo-AII level; Elevated apoA-II level; Elevated apolipoprotein A-II level\n'}


{'id': 'HP_0031801', 'url': 'http://purl.obolibrary.org/obo/HP_0031801', 'lbl': 'Vocal cord dysfunction', 'desc': 'label: Vocal cord dysfunction\ndefinition : Any functional anomaly of the vocal cord.\nsynonyms :\n'}


{'id': 'HP_0031803', 'url': 'http://purl.obolibrary.org/obo/HP_0031803', 'lbl': 'Fundus hemorrhage', 'desc': 'label: Fundus hemorrhage\ndefinition : Bleeding within the fundus of the eye.\nsynonyms :Fundus haemorrhage\n'}


{'id': 'HP_0031804', 'url': 'http://purl.obolibrary.org/obo/HP_0031804', 'lbl': 'Premacular hemorrhage', 'desc': 'label: Premacular hemorrhage\ndefinition : \nsynonyms :Premacular haemorrhage\n'}


{'id': 'HP_0031805', 'url': 'http://purl.obolibrary.org/obo/HP_0031805', 'lbl': 'Intraretinal hemorrhage', 'desc': "label: Intraretinal hemorrhage\ndefinition : A subtype of fundus hemorrhage occurring within the neurosensory retina. Intraretinal haemorrhages may be 'dot' or' blot' shaped or flame shaped depending upon their depth within the retina.\nsynonyms :Intraretinal haemorrhage\n"}


{'id': 'HP_0031806', 'url': 'http://purl.obolibrary.org/obo/HP_0031806', 'lbl': 'Abnormal basophil count', 'desc': 'label: Abnormal basophil count\ndefinition : Any deviation from the normal number of basophils per volume in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0031807', 'url': 'http://purl.obolibrary.org/obo/HP_0031807', 'lbl': 'Increased basophil count', 'desc': 'label: Increased basophil count\ndefinition : An abnormally increased count of basophils per volume in the blood circulation.\nsynonyms :Basophilia\n'}


{'id': 'HP_0031808', 'url': 'http://purl.obolibrary.org/obo/HP_0031808', 'lbl': 'Decreased basophil count', 'desc': 'label: Decreased basophil count\ndefinition : An abnormally reduced count of basophils per volume in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0031809', 'url': 'http://purl.obolibrary.org/obo/HP_0031809', 'lbl': "Archibald's sign", 'desc': "label: Archibald's sign\ndefinition : Shortening of the fourth and fifth metacarpals when the fist is clenched.\nsynonyms :Archibald's metacarpal sign; Knuckle dimple\n"}


{'id': 'HP_0031810', 'url': 'http://purl.obolibrary.org/obo/HP_0031810', 'lbl': 'Anti-ganglioside antibody positivity', 'desc': 'label: Anti-ganglioside antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react to gangliosides.\nsynonyms :\n'}


{'id': 'HP_0031811', 'url': 'http://purl.obolibrary.org/obo/HP_0031811', 'lbl': 'Bilirubinuria', 'desc': 'label: Bilirubinuria\ndefinition : Presence of conjugated bilirubin in the urine.\nsynonyms :\n'}


{'id': 'HP_0031812', 'url': 'http://purl.obolibrary.org/obo/HP_0031812', 'lbl': 'Nitrituria', 'desc': 'label: Nitrituria\ndefinition : Presence of nitrites in the urine.\nsynonyms :\n'}


{'id': 'HP_0031813', 'url': 'http://purl.obolibrary.org/obo/HP_0031813', 'lbl': 'Colonic eosinophilia', 'desc': 'label: Colonic eosinophilia\ndefinition : An excess of eosinophilic cells in colonic tissue, i.e., eosinophilic infiltration in the colon.\nsynonyms :Eosinophilic colitis; Eosinophilic infiltration in the colon\n'}


{'id': 'HP_0031814', 'url': 'http://purl.obolibrary.org/obo/HP_0031814', 'lbl': 'Palilalia', 'desc': "label: Palilalia\ndefinition : Repetition of one's own words or phrases.\nsynonyms :\n"}


{'id': 'HP_0031815', 'url': 'http://purl.obolibrary.org/obo/HP_0031815', 'lbl': 'Abnormal oral physiology', 'desc': 'label: Abnormal oral physiology\ndefinition : A functional anomaly of the mouth (which is also known as the oral cavity).\nsynonyms :\n'}


{'id': 'HP_0031816', 'url': 'http://purl.obolibrary.org/obo/HP_0031816', 'lbl': 'Abnormal oral morphology', 'desc': 'label: Abnormal oral morphology\ndefinition : Any structural anomaly of the mouth, which is also known as the oral cavity.\nsynonyms :\n'}


{'id': 'HP_0031817', 'url': 'http://purl.obolibrary.org/obo/HP_0031817', 'lbl': 'Decreased circulating parathyroid hormone level', 'desc': 'label: Decreased circulating parathyroid hormone level\ndefinition : An abnormally decreased concentration of parathyroid hormone.\nsynonyms :Decreased circulating PTH level; Decreased serum PTH; Decreased serum parathyroid hormone; Decreased serum parathyroid hormone level\n'}