{'id': 'HP_0002692', 'url': 'http://purl.obolibrary.org/obo/HP_0002692', 'lbl': 'Hypoplastic facial bones', 'desc': 'label: Hypoplastic facial bones\ndefinition : \nsynonyms :Hypoplasia of facial skeleton; Small facial bones; Small facial skeleton; Underdevelopment of facial bones; Underdevelopment of facial skeleton; Decreased size of facial bones; Decreased size of facial skeleton; Flattening of facial bones; Flattening of facial skeleton; Hypotrophic facial bones; Hypotrophic facial skeleton\n'}


{'id': 'HP_0002693', 'url': 'http://purl.obolibrary.org/obo/HP_0002693', 'lbl': 'Abnormal skull base morphology', 'desc': 'label: Abnormal skull base morphology\ndefinition : An abnormality of the base of the skull, which forms the floor of the cranial cavity and separates the brain from other facial structures. The skull base is made up of five bones: the ethmoid, sphenoid, occipital, paired frontal, and paired parietal bones, and is subdivided into 3 regions: the anterior, middle, and posterior cranial fossae. The petro-occipital fissure subdivides the middle cranial fossa into 1 central component and 2 lateral components.\nsynonyms :Abnormality of cranial base; Abnormality of the skull base\n'}


{'id': 'HP_0002694', 'url': 'http://purl.obolibrary.org/obo/HP_0002694', 'lbl': 'Sclerosis of skull base', 'desc': 'label: Sclerosis of skull base\ndefinition : Increased bone density of the skull base without significant changes in bony contour.\nsynonyms :Dense bone of skull base; Hyperossification of skull base; Hyperostosis of skull base; Marked sclerosis of skull base; Sclerosis of cranial base; Sclerosis of the skull base; Sclerotic skull base; HyperCalcification of skull base; HyperMineralization of skull base\n'}


{'id': 'HP_0002695', 'url': 'http://purl.obolibrary.org/obo/HP_0002695', 'lbl': 'obsolete Symmetrical, oval parietal bone defects', 'desc': 'label: obsolete Symmetrical, oval parietal bone defects\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002696', 'url': 'http://purl.obolibrary.org/obo/HP_0002696', 'lbl': 'Abnormal parietal bone morphology', 'desc': 'label: Abnormal parietal bone morphology\ndefinition : Any abnormality of the parietal bone of the skull.\nsynonyms :Abnormality of the parietal bone; Abnormality of the parietal bone of skull\n'}


{'id': 'HP_0002697', 'url': 'http://purl.obolibrary.org/obo/HP_0002697', 'lbl': 'Parietal foramina', 'desc': 'label: Parietal foramina\ndefinition : The presence of symmetrical and circular openings (foramina) in the parietal bone ranging in size from a few millimeters to several centimeters wide.\nsynonyms :Persistent foramina of the parietal bones; Symmetrical, oval defects in the parietal bone; Symmetrical, oval parietal bone defects; Holes in parietal bones; Openings in parietal bones\n'}


{'id': 'HP_0002699', 'url': 'http://purl.obolibrary.org/obo/HP_0002699', 'lbl': 'Abnormal foramen magnum morphology', 'desc': 'label: Abnormal foramen magnum morphology\ndefinition : Any abnormality of the foramen magnum.\nsynonyms :Abnormality of the foramen magnum\n'}


{'id': 'HP_0002700', 'url': 'http://purl.obolibrary.org/obo/HP_0002700', 'lbl': 'Large foramen magnum', 'desc': 'label: Large foramen magnum\ndefinition : An abnormal increase in the size of the foramen magnum.\nsynonyms :Big foramen magnum; Dilation of foramen magnum; Enlarged foramen magnum; Wide foramen magnum; Increased circumference of foramen magnum; Increased diameter of foramen magnum\n'}


{'id': 'HP_0002703', 'url': 'http://purl.obolibrary.org/obo/HP_0002703', 'lbl': 'Abnormality of skull ossification', 'desc': 'label: Abnormality of skull ossification\ndefinition : An abnormality of the process of ossification of the skull.\nsynonyms :Abnormality of skull bone formation; Abnormality of ossification of calvarium; Abnormality of ossification of cranium; Abnormality of bone calcification of calvarium; Abnormality of bone calcification of cranium; Abnormality of bone calcification of skull; Abnormality of bone formation of calvarium; Abnormality of bone formation of cranium; Abnormality of bone mineralization of calvarium; Abnormality of bone mineralization of cranium; Abnormality of bone mineralization of skull\n'}


{'id': 'HP_0002705', 'url': 'http://purl.obolibrary.org/obo/HP_0002705', 'lbl': 'High, narrow palate', 'desc': 'label: High, narrow palate\ndefinition : The presence of a high and narrow palate.\nsynonyms :Gothic palate; High narrow palate; High vaulted palate; High, narrow palate; Narrow and high arched palate; Narrow, high-arched palate; Narrow, high-arched roof of mouth; Narrow, highly arched palate; Narrow, highly arched roof of mouth\n'}


{'id': 'HP_0002707', 'url': 'http://purl.obolibrary.org/obo/HP_0002707', 'lbl': 'Palate telangiectasia', 'desc': 'label: Palate telangiectasia\ndefinition : The presence of small (ca. 0.5-1.0 mm) dilated blood vessels near the surface of the mucous membranes of the palate.\nsynonyms :Palatal angioectasia; Palatal telangiectasia; Palate telangiectases; Palate teleangiectases; Telangiectasia of the roof of the mouth; Palatal spider veins; Spider veins of the roof of the mouth\n'}


{'id': 'HP_0002708', 'url': 'http://purl.obolibrary.org/obo/HP_0002708', 'lbl': 'Prominent median palatal raphe', 'desc': 'label: Prominent median palatal raphe\ndefinition : Unusual prominence of the median palatal raphe, which is the ridge formed by the fusion of the two plates of the skull that form the hard palate.\nsynonyms :Prominent central palatal ridge; Prominent central ridge on roof of the mouth; Prominent medial palatal suture\n'}


{'id': 'HP_0002710', 'url': 'http://purl.obolibrary.org/obo/HP_0002710', 'lbl': 'Commissural lip pit', 'desc': 'label: Commissural lip pit\ndefinition : A depression located at an oral commissure.\nsynonyms :Commissural labial pits; Commissural pit; Lip pits at corners of the mouth; Pits at the corners of the lips\n'}


{'id': 'HP_0002711', 'url': 'http://purl.obolibrary.org/obo/HP_0002711', 'lbl': 'Exaggerated median tongue furrow', 'desc': 'label: Exaggerated median tongue furrow\ndefinition : Increased depth of the median tongue furrow.\nsynonyms :Deep central lingual furrow; Deep central lingual groove; Deep central tongue furrow; Deep central tongue groove; Deep median lingual furrow; Deep median lingual groove; Deep median tongue furrow; Deep median tongue groove; Exaggerated median lingual furrow\n'}


{'id': 'HP_0002714', 'url': 'http://purl.obolibrary.org/obo/HP_0002714', 'lbl': 'Downturned corners of mouth', 'desc': 'label: Downturned corners of mouth\ndefinition : A morphological abnormality of the mouth in which the angle of the mouth is downturned. The oral commissures are positioned inferior to the midline labial fissure.\nsynonyms :Downturned corners of mouth; Downturned corners of the mouth; Downturned mouth; Downturned oral commisures\n'}


{'id': 'HP_0002715', 'url': 'http://purl.obolibrary.org/obo/HP_0002715', 'lbl': 'Abnormality of the immune system', 'desc': 'label: Abnormality of the immune system\ndefinition : An abnormality of the immune system.\nsynonyms :Abnormality of the immune system; Immunological abnormality\n'}


{'id': 'HP_0002716', 'url': 'http://purl.obolibrary.org/obo/HP_0002716', 'lbl': 'Lymphadenopathy', 'desc': 'label: Lymphadenopathy\ndefinition : Enlargment (swelling) of a lymph node.\nsynonyms :Lymph node hyperplasia; Swollen lymph nodes\n'}


{'id': 'HP_0002717', 'url': 'http://purl.obolibrary.org/obo/HP_0002717', 'lbl': 'Adrenal overactivity', 'desc': 'label: Adrenal overactivity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002718', 'url': 'http://purl.obolibrary.org/obo/HP_0002718', 'lbl': 'Recurrent bacterial infections', 'desc': 'label: Recurrent bacterial infections\ndefinition : Increased susceptibility to bacterial infections, as manifested by recurrent episodes of bacterial infection.\nsynonyms :Bacterial infections, recurrent; Frequent bacterial infections; Frequent pyogenic infections; Increased susceptibility to bacterial infections; Recurrent bacterial infections; Recurrent major bacterial infections; Recurrent pyogenic infections; Susceptibility to pyogenic infection; Prone to bacterial infection\n'}


{'id': 'HP_0002719', 'url': 'http://purl.obolibrary.org/obo/HP_0002719', 'lbl': 'Recurrent infections', 'desc': 'label: Recurrent infections\ndefinition : Increased susceptibility to infections.\nsynonyms :Frequent infections; Frequent, severe infections; Increased frequency of infection; Predisposition to infections; Recurrent infections; Susceptibility to infection; infections, recurrent\n'}


{'id': 'HP_0002720', 'url': 'http://purl.obolibrary.org/obo/HP_0002720', 'lbl': 'Decreased circulating IgA level', 'desc': 'label: Decreased circulating IgA level\ndefinition : Decreased levels of immunoglobulin A (IgA).\nsynonyms :Decreased IgA; Decreased immunoglobulin A; Gamma-A globulin deficiency; IgA deficiency; Low levels of immunoglobulin A; Reduced IgA levels\n'}


{'id': 'HP_0002721', 'url': 'http://purl.obolibrary.org/obo/HP_0002721', 'lbl': 'Immunodeficiency', 'desc': 'label: Immunodeficiency\ndefinition : Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.\nsynonyms :Decreased immune function; Immune deficiency\n'}


{'id': 'HP_0002722', 'url': 'http://purl.obolibrary.org/obo/HP_0002722', 'lbl': 'Recurrent abscess formation', 'desc': 'label: Recurrent abscess formation\ndefinition : An increased susceptibility to abscess formation, as manifested by a medical history of recurrent abscesses.\nsynonyms :\n'}


{'id': 'HP_0002723', 'url': 'http://purl.obolibrary.org/obo/HP_0002723', 'lbl': 'Absence of bactericidal oxidative respiratory burst in phagocytes', 'desc': 'label: Absence of bactericidal oxidative respiratory burst in phagocytes\ndefinition : An absence of the phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.\nsynonyms :\n'}


{'id': 'HP_0002724', 'url': 'http://purl.obolibrary.org/obo/HP_0002724', 'lbl': 'Recurrent Aspergillus infections', 'desc': 'label: Recurrent Aspergillus infections\ndefinition : An increased susceptibility to Aspergillus infections, as manifested by a history of recurrent episodes of Aspergillus infections.\nsynonyms :Aspergillus infections, recurrent\n'}


{'id': 'HP_0002725', 'url': 'http://purl.obolibrary.org/obo/HP_0002725', 'lbl': 'Systemic lupus erythematosus', 'desc': 'label: Systemic lupus erythematosus\ndefinition : A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes.\nsynonyms :SLE\n'}


{'id': 'HP_0002726', 'url': 'http://purl.obolibrary.org/obo/HP_0002726', 'lbl': 'Recurrent Staphylococcus aureus infections', 'desc': 'label: Recurrent Staphylococcus aureus infections\ndefinition : Increased susceptibility to Staphylococcus aureus infections, as manifested by recurrent episodes of Staphylococcus aureus infection.\nsynonyms :Staphylococcus aureus infections, recurrent\n'}


{'id': 'HP_0002728', 'url': 'http://purl.obolibrary.org/obo/HP_0002728', 'lbl': 'Chronic mucocutaneous candidiasis', 'desc': 'label: Chronic mucocutaneous candidiasis\ndefinition : Recurrent or persistent superficial Candida infections of the skin, mucous membranes, and nails.\nsynonyms :Chronic candidiasis of mucosa, skin and nails; Mucocutaneous candidiasis\n'}


{'id': 'HP_0002729', 'url': 'http://purl.obolibrary.org/obo/HP_0002729', 'lbl': 'Follicular hyperplasia', 'desc': 'label: Follicular hyperplasia\ndefinition : Lymphadenopathy (enlargement of lymph nodes) owing to hyperplasia of follicular (germinal) centers.\nsynonyms :\n'}


{'id': 'HP_0002730', 'url': 'http://purl.obolibrary.org/obo/HP_0002730', 'lbl': 'Chronic noninfectious lymphadenopathy', 'desc': 'label: Chronic noninfectious lymphadenopathy\ndefinition : A chronic form of lymphadenopathy that is not related to infection.\nsynonyms :\n'}


{'id': 'HP_0002731', 'url': 'http://purl.obolibrary.org/obo/HP_0002731', 'lbl': 'Decreased lymphocyte apoptosis', 'desc': 'label: Decreased lymphocyte apoptosis\ndefinition : A reduction in the rate of apoptosis in lymphocytes.\nsynonyms :Defective lymphocyte apoptosis\n'}


{'id': 'HP_0002732', 'url': 'http://purl.obolibrary.org/obo/HP_0002732', 'lbl': 'Lymph node hypoplasia', 'desc': 'label: Lymph node hypoplasia\ndefinition : Underdevelopment of the lymph nodes.\nsynonyms :Small lymph nodes\n'}


{'id': 'HP_0002733', 'url': 'http://purl.obolibrary.org/obo/HP_0002733', 'lbl': 'Abnormal lymph node morphology', 'desc': 'label: Abnormal lymph node morphology\ndefinition : A structural lymph node abnormality.\nsynonyms :Abnormal lymph node histology; Abnormality of the lymph nodes\n'}


{'id': 'HP_0002737', 'url': 'http://purl.obolibrary.org/obo/HP_0002737', 'lbl': 'Thick skull base', 'desc': 'label: Thick skull base\ndefinition : \nsynonyms :Increased thickness of bone of skull base; Increased thickness of skull base; Thick skull base\n'}


{'id': 'HP_0002738', 'url': 'http://purl.obolibrary.org/obo/HP_0002738', 'lbl': 'Hypoplastic frontal sinuses', 'desc': 'label: Hypoplastic frontal sinuses\ndefinition : Underdevelopment of frontal sinus.\nsynonyms :Decreased volume of frontal sinuses; Small frontal sinuses; Underdeveloped frontal sinuses; Decreased pneumatization of frontal sinus; Hypotrophic frontal sinus\n'}


{'id': 'HP_0002740', 'url': 'http://purl.obolibrary.org/obo/HP_0002740', 'lbl': 'Recurrent E. coli infections', 'desc': 'label: Recurrent E. coli infections\ndefinition : Increased susceptibility to infections with Escherichia coli, as manifested by recurrent episodes of infection with this agent.\nsynonyms :E coli infections; E coli infections, recurrent\n'}


{'id': 'HP_0002741', 'url': 'http://purl.obolibrary.org/obo/HP_0002741', 'lbl': 'Recurrent Serratia marcescens infections', 'desc': 'label: Recurrent Serratia marcescens infections\ndefinition : Increased susceptibility to Serratia marcescens infections, as manifested by recurrent episodes of Serratia marcescens infection.\nsynonyms :\n'}


{'id': 'HP_0002742', 'url': 'http://purl.obolibrary.org/obo/HP_0002742', 'lbl': 'Recurrent Klebsiella infections', 'desc': 'label: Recurrent Klebsiella infections\ndefinition : Increased susceptibility to Klebsiella infections, as manifested by recurrent episodes of Klebsiella infection.\nsynonyms :Klebsiella infections, recurrent\n'}


{'id': 'HP_0002743', 'url': 'http://purl.obolibrary.org/obo/HP_0002743', 'lbl': 'Recurrent enteroviral infections', 'desc': 'label: Recurrent enteroviral infections\ndefinition : Increased susceptibility to enteroviral infections, as manifested by recurrent episodes of enteroviral infection.\nsynonyms :\n'}


{'id': 'HP_0002744', 'url': 'http://purl.obolibrary.org/obo/HP_0002744', 'lbl': 'Bilateral cleft lip and palate', 'desc': 'label: Bilateral cleft lip and palate\ndefinition : Cleft lip and cleft palate affecting both sides of the face.\nsynonyms :Bilateral cleft lip and cleft palate; Right and left cleft lip and palate\n'}


{'id': 'HP_0002745', 'url': 'http://purl.obolibrary.org/obo/HP_0002745', 'lbl': 'Oral leukoplakia', 'desc': 'label: Oral leukoplakia\ndefinition : A thickened white patch on the oral mucosa that cannot be rubbed off.\nsynonyms :Oral idiopathic keratosis; Oral idiopathic leukoplakia; Oral idiopathic white patch; Oral leucoplakia; Oral leukokeratosis; Oral leukoplasia; Oral white patch; Oral white plaque; leukokeratosis\n'}


{'id': 'HP_0002747', 'url': 'http://purl.obolibrary.org/obo/HP_0002747', 'lbl': 'Respiratory insufficiency due to muscle weakness', 'desc': 'label: Respiratory insufficiency due to muscle weakness\ndefinition : \nsynonyms :Decreased lung function due to weak breathing muscles; Decreased respiratory function due to muscle weakness; Respiratory distress due to muscle weakness; Respiratory failure due to muscle weakness; Respiratory muscle weakness\n'}


{'id': 'HP_0002748', 'url': 'http://purl.obolibrary.org/obo/HP_0002748', 'lbl': 'Rickets', 'desc': 'label: Rickets\ndefinition : Rickets is divided into two major categories including calcipenic and phosphopenic. Hypophosphatemia is described as a common manifestation of both categories. Hypophosphatemic rickets is the most common type of rickets that is characterized by low levels of serum phosphate, resistance to ultraviolet radiation or vitamin D intake. There are several issues involved in hypophosphatemic rickets such as calcium, vitamin D, phosphorus deficiencies. Moreover, other disorder can be associated with its occurrence such as absorption defects due to pancreatic, intestinal, gastric, and renal disorders and hepatobiliary disease. Symptoms are usually seen in childhood and can be varied in severity. Severe forms may be linked to bowing of the legs, poor bone growth, and short stature as well as joint and bone pain. Hypophosphatemic rickets are associated with renal excretion of phosphate, hypophosphatemia, and mineral defects in bones. The familial type of the disease is the most common type of rickets.\nsynonyms :Weak and soft bones\n'}


{'id': 'HP_0002749', 'url': 'http://purl.obolibrary.org/obo/HP_0002749', 'lbl': 'Osteomalacia', 'desc': 'label: Osteomalacia\ndefinition : Osteomalacia is a general term for bone weakness owing to a defect in mineralization of the protein framework known as osteoid. This defective mineralization is mainly caused by lack in vitamin D. Osteomalacia in children is known as rickets.\nsynonyms :Softening of the bones\n'}


{'id': 'HP_0002750', 'url': 'http://purl.obolibrary.org/obo/HP_0002750', 'lbl': 'Delayed skeletal maturation', 'desc': 'label: Delayed skeletal maturation\ndefinition : A decreased rate of skeletal maturation. Delayed skeletal maturation can be diagnosed on the basis of an estimation of the bone age from radiographs of specific bones in the human body.\nsynonyms :Delayed bone age; Delayed bone age before puberty; Delayed bone maturation; Delayed skeletal development; Retarded bone age; Skeletal maturation retardation; Retarded ossification\n'}


{'id': 'HP_0002751', 'url': 'http://purl.obolibrary.org/obo/HP_0002751', 'lbl': 'Kyphoscoliosis', 'desc': 'label: Kyphoscoliosis\ndefinition : An abnormal curvature of the spine in both a coronal (lateral) and sagittal (back-to-front) plane.\nsynonyms :\n'}


{'id': 'HP_0002752', 'url': 'http://purl.obolibrary.org/obo/HP_0002752', 'lbl': 'Sparse bone trabeculae', 'desc': 'label: Sparse bone trabeculae\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002753', 'url': 'http://purl.obolibrary.org/obo/HP_0002753', 'lbl': 'Thin bony cortex', 'desc': 'label: Thin bony cortex\ndefinition : Abnormal thinning of the cortical region of bones.\nsynonyms :Thin cortices\n'}


{'id': 'HP_0002754', 'url': 'http://purl.obolibrary.org/obo/HP_0002754', 'lbl': 'Osteomyelitis', 'desc': 'label: Osteomyelitis\ndefinition : Osteomyelitis is an inflammatory process accompanied by bone destruction and caused by an infecting microorganism.\nsynonyms :Bone infection\n'}


{'id': 'HP_0002755', 'url': 'http://purl.obolibrary.org/obo/HP_0002755', 'lbl': 'obsolete Osteomyelitis due to immunodeficiency', 'desc': 'label: obsolete Osteomyelitis due to immunodeficiency\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002756', 'url': 'http://purl.obolibrary.org/obo/HP_0002756', 'lbl': 'Pathologic fracture', 'desc': 'label: Pathologic fracture\ndefinition : A pathologic fracture occurs when a bone breaks in an area that is weakened secondarily to another disease process such as tumor, infection, and certain inherited bone disorders. A pathologic fracture can occur without a degree of trauma required to cause fracture in healthy bone.\nsynonyms :Spontaneous fracture; Pathologic fractures; Spontaneous fractures\n'}


{'id': 'HP_0002757', 'url': 'http://purl.obolibrary.org/obo/HP_0002757', 'lbl': 'Recurrent fractures', 'desc': 'label: Recurrent fractures\ndefinition : The repeated occurrence of bone fractures (implying an abnormally increased tendency for fracture).\nsynonyms :Frequent fractures; Increased fracture rate; Increased fractures; Multiple fractures; Multiple spontaneous fractures; Recurrent fractures; Varying degree of multiple fractures\n'}


{'id': 'HP_0002758', 'url': 'http://purl.obolibrary.org/obo/HP_0002758', 'lbl': 'Osteoarthritis', 'desc': 'label: Osteoarthritis\ndefinition : Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.\nsynonyms :Degenerative joint disease\n'}


{'id': 'HP_0002761', 'url': 'http://purl.obolibrary.org/obo/HP_0002761', 'lbl': 'Generalized joint laxity', 'desc': 'label: Generalized joint laxity\ndefinition : Joint hypermobility (ability of a joint to move beyond its normal range of motion) affecting many or all joints of the body.\nsynonyms :Generalised joint laxity; Hypermobility of all joints; Joint laxity, generalised; Joint laxity, generalized\n'}


{'id': 'HP_0002762', 'url': 'http://purl.obolibrary.org/obo/HP_0002762', 'lbl': 'Multiple exostoses', 'desc': 'label: Multiple exostoses\ndefinition : Presence of more than one exostosis. An exostosis is a benign growth the projects outward from the bone surface. It is capped by cartilage, and arises from a bone that develops from cartilage.\nsynonyms :\n'}


{'id': 'HP_0002763', 'url': 'http://purl.obolibrary.org/obo/HP_0002763', 'lbl': 'Abnormal cartilage morphology', 'desc': 'label: Abnormal cartilage morphology\ndefinition : Any morphological abnormality of cartilage.\nsynonyms :Abnormal shape of cartilage; Abnormality of cartilage morphology\n'}


{'id': 'HP_0002764', 'url': 'http://purl.obolibrary.org/obo/HP_0002764', 'lbl': 'Stippled chondral calcification', 'desc': 'label: Stippled chondral calcification\ndefinition : Punctate (speckled, dot-like) deposition of calcium of calcium salts in the articular cartilage (cartilage located in joints).\nsynonyms :\n'}


{'id': 'HP_0002766', 'url': 'http://purl.obolibrary.org/obo/HP_0002766', 'lbl': 'Relatively short spine', 'desc': 'label: Relatively short spine\ndefinition : \nsynonyms :Relatively short spine\n'}


{'id': 'HP_0002773', 'url': 'http://purl.obolibrary.org/obo/HP_0002773', 'lbl': 'obsolete Small vertebral bodies', 'desc': 'label: obsolete Small vertebral bodies\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002777', 'url': 'http://purl.obolibrary.org/obo/HP_0002777', 'lbl': 'Tracheal stenosis', 'desc': 'label: Tracheal stenosis\ndefinition : \nsynonyms :Narrowing of windpipe\n'}


{'id': 'HP_0002778', 'url': 'http://purl.obolibrary.org/obo/HP_0002778', 'lbl': 'Abnormal tracheal morphology', 'desc': 'label: Abnormal tracheal morphology\ndefinition : A structural anomaly of the trachea.\nsynonyms :Abnormal trachea morphology; Abnormality of the trachea; Tracheal disease\n'}


{'id': 'HP_0002779', 'url': 'http://purl.obolibrary.org/obo/HP_0002779', 'lbl': 'Tracheomalacia', 'desc': 'label: Tracheomalacia\ndefinition : \nsynonyms :Floppy windpipe\n'}


{'id': 'HP_0002780', 'url': 'http://purl.obolibrary.org/obo/HP_0002780', 'lbl': 'Bronchomalacia', 'desc': 'label: Bronchomalacia\ndefinition : Weakness or softness of the cartilage in the walls of the bronchial tubes.\nsynonyms :\n'}


{'id': 'HP_0002781', 'url': 'http://purl.obolibrary.org/obo/HP_0002781', 'lbl': 'Upper airway obstruction', 'desc': 'label: Upper airway obstruction\ndefinition : Increased resistance to the passage of air in the upper airway.\nsynonyms :Upper airway obstruction\n'}


{'id': 'HP_0002783', 'url': 'http://purl.obolibrary.org/obo/HP_0002783', 'lbl': 'Recurrent lower respiratory tract infections', 'desc': 'label: Recurrent lower respiratory tract infections\ndefinition : An increased susceptibility to lower respiratory tract infections as manifested by a history of recurrent lower respiratory tract infections.\nsynonyms :Chronic lung infections; Lower respiratory tract infections; Recurrent chest infections\n'}


{'id': 'HP_0002786', 'url': 'http://purl.obolibrary.org/obo/HP_0002786', 'lbl': 'Tracheobronchomalacia', 'desc': 'label: Tracheobronchomalacia\ndefinition : Weakness of the cartilage in the trachea and the bronchi, resulting in a floppy (non-rigid) airway. Affected persons may have difficulties to maintain patency of the airways.\nsynonyms :\n'}


{'id': 'HP_0002787', 'url': 'http://purl.obolibrary.org/obo/HP_0002787', 'lbl': 'Tracheal calcification', 'desc': 'label: Tracheal calcification\ndefinition : Calcification (abnormal deposits of calcium) in the tracheal tissues.\nsynonyms :Calcification of the trachea; Tracheal calcifications; Tracheal ectopic calcification\n'}


{'id': 'HP_0002788', 'url': 'http://purl.obolibrary.org/obo/HP_0002788', 'lbl': 'Recurrent upper respiratory tract infections', 'desc': 'label: Recurrent upper respiratory tract infections\ndefinition : An increased susceptibility to upper respiratory tract infections as manifested by a history of recurrent upper respiratory tract infections (running ears - otitis, sinusitis, pharyngitis, tonsillitis).\nsynonyms :Frequent upper respiratory infections; Frequent upper respiratory tract infections; Recurrent URI; Recurrent colds; Recurrent upper respiratory and lower respiratory infections; Recurrent upper respiratory infection; Recurrent upper respiratory infections; Upper respiratory tract infections; Upper respiratory tract infections, recurrent\n'}


{'id': 'HP_0002789', 'url': 'http://purl.obolibrary.org/obo/HP_0002789', 'lbl': 'Tachypnea', 'desc': 'label: Tachypnea\ndefinition : Very rapid breathing.\nsynonyms :Increased respiratory rate or depth of breathing; Polypnea\n'}


{'id': 'HP_0002790', 'url': 'http://purl.obolibrary.org/obo/HP_0002790', 'lbl': 'Neonatal breathing dysregulation', 'desc': 'label: Neonatal breathing dysregulation\ndefinition : \nsynonyms :Impaired breathing in newborn\n'}


{'id': 'HP_0002791', 'url': 'http://purl.obolibrary.org/obo/HP_0002791', 'lbl': 'Hypoventilation', 'desc': 'label: Hypoventilation\ndefinition : A reduction in the amount of air transported into the pulmonary alveoli by breathing, leading to hypercapnia (increase in the partial pressure of carbon dioxide).\nsynonyms :Alveolar hypoventilation; Slow breathing; Under breathing; Respiratory depression\n'}


{'id': 'HP_0002792', 'url': 'http://purl.obolibrary.org/obo/HP_0002792', 'lbl': 'Reduced vital capacity', 'desc': 'label: Reduced vital capacity\ndefinition : An abnormal reduction on the vital capacity, which is defined as the total lung capacity (volume of air in the lungs at maximal inflation) less the residual volume (i.e., volume of air in the lungs following maximal exhalation) of the lung.\nsynonyms :Decreased vital capacity\n'}


{'id': 'HP_0002793', 'url': 'http://purl.obolibrary.org/obo/HP_0002793', 'lbl': 'Abnormal pattern of respiration', 'desc': 'label: Abnormal pattern of respiration\ndefinition : An anomaly of the rhythm or depth of breathing.\nsynonyms :Abnormal pattern of respiration; Abnormal respiratory patterns; Unusual breathing patterns\n'}


{'id': 'HP_0002795', 'url': 'http://purl.obolibrary.org/obo/HP_0002795', 'lbl': 'Abnormal respiratory system physiology', 'desc': 'label: Abnormal respiratory system physiology\ndefinition : \nsynonyms :Abnormal respiration; Functional respiratory abnormality; Impaired pulmonary function; Respiratory problem\n'}


{'id': 'HP_0002797', 'url': 'http://purl.obolibrary.org/obo/HP_0002797', 'lbl': 'Osteolysis', 'desc': 'label: Osteolysis\ndefinition : Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium.\nsynonyms :Breakdown of bone; Increased bone resorption; Osteolytic defects of bones\n'}


{'id': 'HP_0002803', 'url': 'http://purl.obolibrary.org/obo/HP_0002803', 'lbl': 'Congenital contracture', 'desc': 'label: Congenital contracture\ndefinition : One or more flexion contractures (a bent joint that cannot be straightened actively or passively) that are present at birth.\nsynonyms :Congenital joint contractures; congenital contractures\n'}


{'id': 'HP_0002804', 'url': 'http://purl.obolibrary.org/obo/HP_0002804', 'lbl': 'Arthrogryposis multiplex congenita', 'desc': 'label: Arthrogryposis multiplex congenita\ndefinition : Multiple congenital contractures in different body areas.\nsynonyms :Arthrogryposis; Arthrogryposis multiplex; Arthrogryposis, congenital; Multiple congenital contractures\n'}


{'id': 'HP_0002805', 'url': 'http://purl.obolibrary.org/obo/HP_0002805', 'lbl': 'Accelerated bone age after puberty', 'desc': 'label: Accelerated bone age after puberty\ndefinition : \nsynonyms :Accelerated bone age after puberty\n'}


{'id': 'HP_0002808', 'url': 'http://purl.obolibrary.org/obo/HP_0002808', 'lbl': 'Kyphosis', 'desc': 'label: Kyphosis\ndefinition : Exaggerated anterior convexity of the thoracic vertebral column.\nsynonyms :Gibbus deformity; Hunched back; Hyperkyphosis; Round back\n'}


{'id': 'HP_0002810', 'url': 'http://purl.obolibrary.org/obo/HP_0002810', 'lbl': 'Dumbbell-shaped metaphyses', 'desc': 'label: Dumbbell-shaped metaphyses\ndefinition : \nsynonyms :Dumbbell shaped metaphyses; Dumbbell shaped metaphysis; Dumbbell shaped wide portion of long bone\n'}


{'id': 'HP_0002812', 'url': 'http://purl.obolibrary.org/obo/HP_0002812', 'lbl': 'Coxa vara', 'desc': 'label: Coxa vara\ndefinition : Coxa vara includes all forms of decrease of the femoral neck shaft angle (the angle between the neck and the shaft of the femur) to less than 120 degrees.\nsynonyms :\n'}


{'id': 'HP_0002813', 'url': 'http://purl.obolibrary.org/obo/HP_0002813', 'lbl': 'Abnormality of limb bone morphology', 'desc': 'label: Abnormality of limb bone morphology\ndefinition : Any abnormality of bones of the arms or legs.\nsynonyms :Abnormal shape of limb bone; Arm and/or leg bone differences; Limb abnormality\n'}


{'id': 'HP_0002814', 'url': 'http://purl.obolibrary.org/obo/HP_0002814', 'lbl': 'Abnormality of the lower limb', 'desc': 'label: Abnormality of the lower limb\ndefinition : An abnormality of the leg.\nsynonyms :Abnormality of the leg; Abnormality of the lower limb; Lower limb deformities\n'}


{'id': 'HP_0002815', 'url': 'http://purl.obolibrary.org/obo/HP_0002815', 'lbl': 'Abnormality of the knee', 'desc': 'label: Abnormality of the knee\ndefinition : An abnormality of the knee joint or surrounding structures.\nsynonyms :Abnormality of the knee\n'}


{'id': 'HP_0002816', 'url': 'http://purl.obolibrary.org/obo/HP_0002816', 'lbl': 'Genu recurvatum', 'desc': 'label: Genu recurvatum\ndefinition : An abnormally increased extension of the knee joint, so that the knee can bend backwards.\nsynonyms :Back knee; Genu recurvata; Knee hyperextension\n'}


{'id': 'HP_0002817', 'url': 'http://purl.obolibrary.org/obo/HP_0002817', 'lbl': 'Abnormality of the upper limb', 'desc': 'label: Abnormality of the upper limb\ndefinition : An abnormality of the arm.\nsynonyms :Abnormality of the arm; Abnormality of the upper limb\n'}


{'id': 'HP_0002818', 'url': 'http://purl.obolibrary.org/obo/HP_0002818', 'lbl': 'Abnormal morphology of the radius', 'desc': 'label: Abnormal morphology of the radius\ndefinition : An abnormality of the radius.\nsynonyms :Abnormality of the radius\n'}


{'id': 'HP_0002821', 'url': 'http://purl.obolibrary.org/obo/HP_0002821', 'lbl': 'Neuropathic arthropathy', 'desc': 'label: Neuropathic arthropathy\ndefinition : \nsynonyms :Charcot arthropathy; Charcot joint\n'}


{'id': 'HP_0002822', 'url': 'http://purl.obolibrary.org/obo/HP_0002822', 'lbl': 'Hyperplasia of the femoral trochanters', 'desc': 'label: Hyperplasia of the femoral trochanters\ndefinition : \nsynonyms :Hyperplastic femoral trochanters\n'}


{'id': 'HP_0002823', 'url': 'http://purl.obolibrary.org/obo/HP_0002823', 'lbl': 'Abnormality of femur morphology', 'desc': 'label: Abnormality of femur morphology\ndefinition : Any anomaly of the structure of the femur.\nsynonyms :Abnormality of the femora; Abnormality of the thighbone\n'}


{'id': 'HP_0002825', 'url': 'http://purl.obolibrary.org/obo/HP_0002825', 'lbl': 'Caudal appendage', 'desc': 'label: Caudal appendage\ndefinition : The presence of a tail-like skin appendage located adjacent to the sacrum.\nsynonyms :Coccygeal tail; Human tail\n'}


{'id': 'HP_0002826', 'url': 'http://purl.obolibrary.org/obo/HP_0002826', 'lbl': 'Halberd-shaped pelvis', 'desc': 'label: Halberd-shaped pelvis\ndefinition : An anomalous radiographic appearance of the developing pelvis, in which the greater ischiadic noth (incisura ischiadica major) is shallow and the pelvis takes on the appearance said to resemble a halberd (a weapon especially of the 15th and 16th centuries consisting typically of a battle-ax and pike mounted on a handle).\nsynonyms :Halberd-shaped pelvis bone\n'}


{'id': 'HP_0002827', 'url': 'http://purl.obolibrary.org/obo/HP_0002827', 'lbl': 'Hip dislocation', 'desc': 'label: Hip dislocation\ndefinition : Displacement of the femur from its normal location in the hip joint.\nsynonyms :Dislocated hips; Dislocation of hip; Hip dislocation\n'}


{'id': 'HP_0002828', 'url': 'http://purl.obolibrary.org/obo/HP_0002828', 'lbl': 'Multiple joint contractures', 'desc': 'label: Multiple joint contractures\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002829', 'url': 'http://purl.obolibrary.org/obo/HP_0002829', 'lbl': 'Arthralgia', 'desc': 'label: Arthralgia\ndefinition : Joint pain.\nsynonyms :Arthralgias; Joint pain; Arthritic pain; Joint pains\n'}


{'id': 'HP_0002831', 'url': 'http://purl.obolibrary.org/obo/HP_0002831', 'lbl': 'Long coccyx', 'desc': 'label: Long coccyx\ndefinition : \nsynonyms :Long tailbone\n'}


{'id': 'HP_0002832', 'url': 'http://purl.obolibrary.org/obo/HP_0002832', 'lbl': 'Calcific stippling', 'desc': 'label: Calcific stippling\ndefinition : An abnormal punctate (speckled, dot-like) pattern of calcifications in soft tissues within or surrounding bones (as observed on radiographs).\nsynonyms :Discrete calcific stippling\n'}


{'id': 'HP_0002833', 'url': 'http://purl.obolibrary.org/obo/HP_0002833', 'lbl': 'Cystic angiomatosis of bone', 'desc': 'label: Cystic angiomatosis of bone\ndefinition : Disseminated multifocal hemangiomatous or lymphangiomatous lesions of the skeleton. The lesions are lytic, well-defined, round or oval lesions within the medullary cavity, and they have an intact cortex, and manifest variable peripheral sclerosis and may exhibit endosteal scalloping.\nsynonyms :Lytic cystic lesions in appendicular bones\n'}


{'id': 'HP_0002834', 'url': 'http://purl.obolibrary.org/obo/HP_0002834', 'lbl': 'Flared femoral metaphysis', 'desc': 'label: Flared femoral metaphysis\ndefinition : \nsynonyms :Flared metaphysis of thigh bone\n'}


{'id': 'HP_0002835', 'url': 'http://purl.obolibrary.org/obo/HP_0002835', 'lbl': 'Aspiration', 'desc': 'label: Aspiration\ndefinition : Inspiration of a foreign object into the airway.\nsynonyms :Pulmonary aspiration\n'}


{'id': 'HP_0002836', 'url': 'http://purl.obolibrary.org/obo/HP_0002836', 'lbl': 'Bladder exstrophy', 'desc': 'label: Bladder exstrophy\ndefinition : Eversion of the posterior bladder wall through the congenitally absent lower anterior abdominal wall and anterior bladder wall.\nsynonyms :Ectopia vesicae\n'}


{'id': 'HP_0002837', 'url': 'http://purl.obolibrary.org/obo/HP_0002837', 'lbl': 'Recurrent bronchitis', 'desc': 'label: Recurrent bronchitis\ndefinition : An increased susceptibility to bronchitis as manifested by a history of recurrent bronchitis.\nsynonyms :Bronchitis, recurrent\n'}


{'id': 'HP_0002839', 'url': 'http://purl.obolibrary.org/obo/HP_0002839', 'lbl': 'Urinary bladder sphincter dysfunction', 'desc': 'label: Urinary bladder sphincter dysfunction\ndefinition : Abnormal function of a sphincter of the urinary bladder.\nsynonyms :Sphincter disturbance; Sphincter disturbances\n'}


{'id': 'HP_0002840', 'url': 'http://purl.obolibrary.org/obo/HP_0002840', 'lbl': 'Lymphadenitis', 'desc': 'label: Lymphadenitis\ndefinition : Inflammation of a lymph node.\nsynonyms :Inflammation of the lymph nodes\n'}


{'id': 'HP_0002841', 'url': 'http://purl.obolibrary.org/obo/HP_0002841', 'lbl': 'Recurrent fungal infections', 'desc': 'label: Recurrent fungal infections\ndefinition : Increased susceptibility to fungal infections, as manifested by multiple episodes of fungal infection.\nsynonyms :Recurrent fungal infections\n'}


{'id': 'HP_0002842', 'url': 'http://purl.obolibrary.org/obo/HP_0002842', 'lbl': 'Recurrent Burkholderia cepacia infections', 'desc': 'label: Recurrent Burkholderia cepacia infections\ndefinition : Increased susceptibility to infections with Burkholderia cepacia, as manifested by recurrent episodes of infection with this agent.\nsynonyms :\n'}


{'id': 'HP_0002843', 'url': 'http://purl.obolibrary.org/obo/HP_0002843', 'lbl': 'Abnormal T cell morphology', 'desc': 'label: Abnormal T cell morphology\ndefinition : An abnormality of T cells.\nsynonyms :Abnormal T cells; Abnormality of T cells; Cellular immune defect; Defective cellular immunity\n'}


{'id': 'HP_0002845', 'url': 'http://purl.obolibrary.org/obo/HP_0002845', 'lbl': 'obsolete Increased proportion of peripheral CD3+ T cells', 'desc': 'label: obsolete Increased proportion of peripheral CD3+ T cells\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002846', 'url': 'http://purl.obolibrary.org/obo/HP_0002846', 'lbl': 'Abnormal B cell morphology', 'desc': 'label: Abnormal B cell morphology\ndefinition : A structural abnormality of B cells.\nsynonyms :Abnormal B cells; Abnormality of B cells\n'}


{'id': 'HP_0002847', 'url': 'http://purl.obolibrary.org/obo/HP_0002847', 'lbl': 'Impaired memory B cell generation', 'desc': 'label: Impaired memory B cell generation\ndefinition : Impaired production of memory cells, the B cells that persist for years or an entire lifetime and which confer rapid and enhanced response to secondary challenge.\nsynonyms :\n'}


{'id': 'HP_0002848', 'url': 'http://purl.obolibrary.org/obo/HP_0002848', 'lbl': 'Decreased specific anti-polysaccharide antibody level', 'desc': 'label: Decreased specific anti-polysaccharide antibody level\ndefinition : The presence of normal overall immunoglobulin levels with deficiency of specific immunoglobulins directed against bacterial polysaccharides.\nsynonyms :Depressed antibody response to polysaccharide antigens; Low specific anti-polysaccharide antibody titer; Specific anti-polysaccharide antibody deficiency\n'}


{'id': 'HP_0002849', 'url': 'http://purl.obolibrary.org/obo/HP_0002849', 'lbl': 'Absence of lymph node germinal center', 'desc': 'label: Absence of lymph node germinal center\ndefinition : Absence of germinal centers in lymph nodes. Germinal centers are the parts of lymph nodes in which B lymphocytes proliferate, differentiate, mutate through somatic hypermutation and class switch during antibody responses.\nsynonyms :Absence of lymph node germinal centre; Lymph nodes lack germinal center; Lymph nodes lack germinal centre; Lymphoid germinal center defect; Lymphoid germinal centre defect\n'}


{'id': 'HP_0002850', 'url': 'http://purl.obolibrary.org/obo/HP_0002850', 'lbl': 'Decreased circulating total IgM', 'desc': 'label: Decreased circulating total IgM\ndefinition : An abnormally decreased level of immunoglobulin M (IgM) in blood.\nsynonyms :Decreased IgM; Decreased IgM level; IgM deficiency; Reduced IgM levels\n'}


{'id': 'HP_0002851', 'url': 'http://purl.obolibrary.org/obo/HP_0002851', 'lbl': 'Elevated proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells', 'desc': 'label: Elevated proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells\ndefinition : An abnormally increased proportion of CD4-negative, CD8-negative (double negative or DN) alpha-beta regulatory T cells (Tregs) as compared to total number of T cells.\nsynonyms :Increased number of CD4-/CD8- T cells expressing alpha/beta T-cell receptors\n'}


{'id': 'HP_0002853', 'url': 'http://purl.obolibrary.org/obo/HP_0002853', 'lbl': 'Increased proportion of HLA DR+ T cells', 'desc': 'label: Increased proportion of HLA DR+ T cells\ndefinition : An elevated proportion of T cells that express human leukocyte antigen (HLA)-DR. HLA-DR is an MHC class II cell surface receptor that presents antigens (peptides of at least 9 amino acids), thereby constituting a ligand for the T-cell receptor. HLA-DR can be upregulated in response to immune stimulation.\nsynonyms :\n'}


{'id': 'HP_0002857', 'url': 'http://purl.obolibrary.org/obo/HP_0002857', 'lbl': 'Genu valgum', 'desc': 'label: Genu valgum\ndefinition : The legs angle inward, such that the knees are close together and the ankles far apart.\nsynonyms :Genu valga; Genu valgus; Genua valga; Knee joint valgus deformity; Knock knees\n'}


{'id': 'HP_0002858', 'url': 'http://purl.obolibrary.org/obo/HP_0002858', 'lbl': 'Meningioma', 'desc': 'label: Meningioma\ndefinition : The presence of a meningioma, i.e., a benign tumor originating from the dura mater or arachnoid mater.\nsynonyms :Noncancerous growth of membranes covering brain\n'}


{'id': 'HP_0002859', 'url': 'http://purl.obolibrary.org/obo/HP_0002859', 'lbl': 'Rhabdomyosarcoma', 'desc': 'label: Rhabdomyosarcoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002860', 'url': 'http://purl.obolibrary.org/obo/HP_0002860', 'lbl': 'Squamous cell carcinoma', 'desc': 'label: Squamous cell carcinoma\ndefinition : The presence of squamous cell carcinoma of the skin.\nsynonyms :Squamous cell cancer\n'}


{'id': 'HP_0002861', 'url': 'http://purl.obolibrary.org/obo/HP_0002861', 'lbl': 'Melanoma', 'desc': 'label: Melanoma\ndefinition : The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea).\nsynonyms :Cancer of skin pigment cells; Skin cancer (melanoma); Malignant melanoma\n'}


{'id': 'HP_0002862', 'url': 'http://purl.obolibrary.org/obo/HP_0002862', 'lbl': 'Bladder carcinoma', 'desc': 'label: Bladder carcinoma\ndefinition : The presence of a carcinoma of the urinary bladder.\nsynonyms :\n'}


{'id': 'HP_0002863', 'url': 'http://purl.obolibrary.org/obo/HP_0002863', 'lbl': 'Myelodysplasia', 'desc': 'label: Myelodysplasia\ndefinition : Clonal hematopoietic stem cell disorders characterized by dysplasia (ineffective production) in one or more hematopoietic cell lineages, leading to anemia and cytopenia.\nsynonyms :Myelodysplastic syndrome; Hypoplastic myelodysplasia\n'}


{'id': 'HP_0002864', 'url': 'http://purl.obolibrary.org/obo/HP_0002864', 'lbl': 'Paraganglioma of head and neck', 'desc': 'label: Paraganglioma of head and neck\ndefinition : \nsynonyms :Paragangliomas, head and neck\n'}


{'id': 'HP_0002865', 'url': 'http://purl.obolibrary.org/obo/HP_0002865', 'lbl': 'Medullary thyroid carcinoma', 'desc': 'label: Medullary thyroid carcinoma\ndefinition : The presence of a medullary carcinoma of the thyroid gland.\nsynonyms :Medullary thyroid cancer\n'}


{'id': 'HP_0002866', 'url': 'http://purl.obolibrary.org/obo/HP_0002866', 'lbl': 'Hypoplastic iliac wing', 'desc': 'label: Hypoplastic iliac wing\ndefinition : Underdevelopment of the ilium ala.\nsynonyms :Hypoplastic iliac alae; Hypoplastic iliac wings; Small iliac wings\n'}


{'id': 'HP_0002867', 'url': 'http://purl.obolibrary.org/obo/HP_0002867', 'lbl': 'Abnormal ilium morphology', 'desc': 'label: Abnormal ilium morphology\ndefinition : An abnormality of the ilium, the largest and uppermost bone of the pelvis.\nsynonyms :Abnormality of the ilium; Iliac abnormalities\n'}


{'id': 'HP_0002868', 'url': 'http://purl.obolibrary.org/obo/HP_0002868', 'lbl': 'Narrow iliac wing', 'desc': 'label: Narrow iliac wing\ndefinition : Decreased width of the wing (or ala) of the ilium (which is the large expanded portion which bounds the greater pelvis laterally).\nsynonyms :Narrow iliac wings\n'}


{'id': 'HP_0002869', 'url': 'http://purl.obolibrary.org/obo/HP_0002869', 'lbl': 'Flared iliac wing', 'desc': 'label: Flared iliac wing\ndefinition : Widening of the ilium ala, that is of the wing of the ilium, combined with external rotation, leading to a flared appearance of the iliac wing.\nsynonyms :Flared iliac wings\n'}


{'id': 'HP_0002870', 'url': 'http://purl.obolibrary.org/obo/HP_0002870', 'lbl': 'Obstructive sleep apnea', 'desc': 'label: Obstructive sleep apnea\ndefinition : A condition characterized by obstruction of the airway and by pauses in breathing during sleep occurring many times during the night. Obstructive sleep apnea is related to a relaxation of muscle tone (which normally occurs during sleep) leading to partial collapse of the soft tissues in the airway with resultant obstruction of the air flow.\nsynonyms :Obstructive sleep apnoea\n'}


{'id': 'HP_0002871', 'url': 'http://purl.obolibrary.org/obo/HP_0002871', 'lbl': 'Central apnea', 'desc': 'label: Central apnea\ndefinition : Apnea resulting from depression of the respiratory centers in the medulla oblongata. There is a lack of respiratory effort rather than obstruction of airflow.\nsynonyms :Central apnoea\n'}


{'id': 'HP_0002872', 'url': 'http://purl.obolibrary.org/obo/HP_0002872', 'lbl': 'Apneic episodes precipitated by illness, fatigue, stress', 'desc': 'label: Apneic episodes precipitated by illness, fatigue, stress\ndefinition : Recurrent episodes of apnea that are precipitated by factors such as illness, fatigue, or stress.\nsynonyms :Episodic apnea induced by febrile illness or stress\n'}


{'id': 'HP_0002875', 'url': 'http://purl.obolibrary.org/obo/HP_0002875', 'lbl': 'Exertional dyspnea', 'desc': 'label: Exertional dyspnea\ndefinition : Perceived difficulty to breathe that occurs with exercise or exertion and improves with rest.\nsynonyms :Exertional breathlessness; Exertional dyspnoea; Shortness of breathing upon physical activity\n'}


{'id': 'HP_0002876', 'url': 'http://purl.obolibrary.org/obo/HP_0002876', 'lbl': 'Episodic tachypnea', 'desc': 'label: Episodic tachypnea\ndefinition : Episodes of very rapid breathing.\nsynonyms :Hyperpnea, episodic\n'}


{'id': 'HP_0002877', 'url': 'http://purl.obolibrary.org/obo/HP_0002877', 'lbl': 'Nocturnal hypoventilation', 'desc': 'label: Nocturnal hypoventilation\ndefinition : An abnormal reduction in alveolar ventilation occuring during sleep. This is characterized by a rise in arterial carbon dioxide.\nsynonyms :Hypoventilation during sleep; Nocturnal hypopnea; Nocturnal slow breathing; Nocturnal under breathing\n'}


{'id': 'HP_0002878', 'url': 'http://purl.obolibrary.org/obo/HP_0002878', 'lbl': 'Respiratory failure', 'desc': 'label: Respiratory failure\ndefinition : A severe form of respiratory insufficiency characterized by inadequate gas exchange such that the levels of oxygen or carbon dioxide cannot be maintained within normal limits.\nsynonyms :Respiratory failure\n'}


{'id': 'HP_0002879', 'url': 'http://purl.obolibrary.org/obo/HP_0002879', 'lbl': 'Anisospondyly', 'desc': 'label: Anisospondyly\ndefinition : Abnormally increased variability of the size of the vertebral bodies.\nsynonyms :\n'}


{'id': 'HP_0002880', 'url': 'http://purl.obolibrary.org/obo/HP_0002880', 'lbl': 'obsolete Respiratory difficulties', 'desc': 'label: obsolete Respiratory difficulties\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002882', 'url': 'http://purl.obolibrary.org/obo/HP_0002882', 'lbl': 'Sudden episodic apnea', 'desc': 'label: Sudden episodic apnea\ndefinition : Recurrent bouts of sudden, severe apnea that may be life-threatening.\nsynonyms :\n'}


{'id': 'HP_0002883', 'url': 'http://purl.obolibrary.org/obo/HP_0002883', 'lbl': 'Hyperventilation', 'desc': 'label: Hyperventilation\ndefinition : Hyperventilation refers to an increased pulmonary ventilation rate that is faster than necessary for the exchange of gases. Hyperventilation can result from increased frequency of breathing, an increased tidal volume, or both, and leads to an excess intake of oxygen and the blowing off of carbon dioxide.\nsynonyms :Rapid breathing\n'}


{'id': 'HP_0002884', 'url': 'http://purl.obolibrary.org/obo/HP_0002884', 'lbl': 'Hepatoblastoma', 'desc': 'label: Hepatoblastoma\ndefinition : A kind of neoplasm of the liver that originates from immature liver precursor cells and macroscopically is composed of tissue resembling fetal or mature liver cells or bile ducts.\nsynonyms :\n'}


{'id': 'HP_0002885', 'url': 'http://purl.obolibrary.org/obo/HP_0002885', 'lbl': 'Medulloblastoma', 'desc': 'label: Medulloblastoma\ndefinition : A rapidly growing embryonic tumor arising in the posterior part of the cerebellar vermis and neuroepithelial roof of the fourth ventricle in children. More rarely, medulloblastoma arises in the cerebellum in adults.\nsynonyms :\n'}


{'id': 'HP_0002886', 'url': 'http://purl.obolibrary.org/obo/HP_0002886', 'lbl': 'Vagal paraganglioma', 'desc': 'label: Vagal paraganglioma\ndefinition : A tumor that develops in the retrostyloid compartment of the parapharyngeal space, arising from an island of paraganglion tissue derived from the neural crest that is located on the vagus nerve.\nsynonyms :Glomus vagale tumor; Glomus vagale tumour; Vagal nerve tumors; Vagal nerve tumours; Glomus vagale paraganglioma\n'}


{'id': 'HP_0002888', 'url': 'http://purl.obolibrary.org/obo/HP_0002888', 'lbl': 'Ependymoma', 'desc': 'label: Ependymoma\ndefinition : The presence of an ependymoma of the central nervous system.\nsynonyms :\n'}


{'id': 'HP_0002890', 'url': 'http://purl.obolibrary.org/obo/HP_0002890', 'lbl': 'Thyroid carcinoma', 'desc': 'label: Thyroid carcinoma\ndefinition : The presence of a carcinoma of the thyroid gland.\nsynonyms :\n'}


{'id': 'HP_0002891', 'url': 'http://purl.obolibrary.org/obo/HP_0002891', 'lbl': 'Uterine leiomyosarcoma', 'desc': 'label: Uterine leiomyosarcoma\ndefinition : The presence of a leiomyosarcoma of the uterus.\nsynonyms :\n'}


{'id': 'HP_0002893', 'url': 'http://purl.obolibrary.org/obo/HP_0002893', 'lbl': 'Pituitary adenoma', 'desc': 'label: Pituitary adenoma\ndefinition : A benign epithelial tumor derived from intrinsic cells of the adenohypophysis (anterior pituitary).\nsynonyms :Noncancerous tumor in pituitary gland; Noncancerous tumour in pituitary gland; Pituitary gland adenoma\n'}


{'id': 'HP_0002894', 'url': 'http://purl.obolibrary.org/obo/HP_0002894', 'lbl': 'Neoplasm of the pancreas', 'desc': 'label: Neoplasm of the pancreas\ndefinition : A tumor (abnormal growth of tissue) of the pancreas.\nsynonyms :Cancer of the pancreas; Pancreatic cancer; Neoplasia of the pancreas; Pancreatic tumor; Pancreatic tumour; increased risk of pancreatic cancer\n'}


{'id': 'HP_0002895', 'url': 'http://purl.obolibrary.org/obo/HP_0002895', 'lbl': 'Papillary thyroid carcinoma', 'desc': 'label: Papillary thyroid carcinoma\ndefinition : The presence of a papillary adenocarcinoma of the thyroid gland.\nsynonyms :Papillary carcinoma of thyroid; Thyroid papillary carcinoma\n'}


{'id': 'HP_0002896', 'url': 'http://purl.obolibrary.org/obo/HP_0002896', 'lbl': 'Neoplasm of the liver', 'desc': 'label: Neoplasm of the liver\ndefinition : A tumor (abnormal growth of tissue) of the liver.\nsynonyms :Liver cancer; Liver tumor; Liver tumour\n'}


{'id': 'HP_0002897', 'url': 'http://purl.obolibrary.org/obo/HP_0002897', 'lbl': 'Parathyroid adenoma', 'desc': 'label: Parathyroid adenoma\ndefinition : A benign tumor of the parathyroid gland that can cause hyperparathyroidism.\nsynonyms :Parathyroid adenomas\n'}


{'id': 'HP_0002898', 'url': 'http://purl.obolibrary.org/obo/HP_0002898', 'lbl': 'Embryonal neoplasm', 'desc': 'label: Embryonal neoplasm\ndefinition : \nsynonyms :Embryonal neoplasia; Embryonal tumors; Embryonal tumours\n'}


{'id': 'HP_0002900', 'url': 'http://purl.obolibrary.org/obo/HP_0002900', 'lbl': 'Hypokalemia', 'desc': 'label: Hypokalemia\ndefinition : An abnormally decreased potassium concentration in the blood.\nsynonyms :Low blood potassium levels\n'}


{'id': 'HP_0002901', 'url': 'http://purl.obolibrary.org/obo/HP_0002901', 'lbl': 'Hypocalcemia', 'desc': 'label: Hypocalcemia\ndefinition : An abnormally decreased calcium concentration in the blood.\nsynonyms :Hypocalcaemia; Low blood calcium levels\n'}


{'id': 'HP_0002902', 'url': 'http://purl.obolibrary.org/obo/HP_0002902', 'lbl': 'Hyponatremia', 'desc': 'label: Hyponatremia\ndefinition : An abnormally decreased sodium concentration in the blood.\nsynonyms :Low blood sodium levels\n'}


{'id': 'HP_0002904', 'url': 'http://purl.obolibrary.org/obo/HP_0002904', 'lbl': 'Hyperbilirubinemia', 'desc': 'label: Hyperbilirubinemia\ndefinition : An increased amount of bilirubin in the blood.\nsynonyms :High blood bilirubin levels\n'}


{'id': 'HP_0002905', 'url': 'http://purl.obolibrary.org/obo/HP_0002905', 'lbl': 'Hyperphosphatemia', 'desc': 'label: Hyperphosphatemia\ndefinition : An abnormally increased phosphate concentration in the blood.\nsynonyms :High blood phosphate levels\n'}


{'id': 'HP_0002907', 'url': 'http://purl.obolibrary.org/obo/HP_0002907', 'lbl': 'Microscopic hematuria', 'desc': 'label: Microscopic hematuria\ndefinition : Microscopic hematuria detected by dipstick or microscopic examination of the urine.\nsynonyms :Microhematuria; Occult hematuria; Small amount of blood in urine\n'}


{'id': 'HP_0002908', 'url': 'http://purl.obolibrary.org/obo/HP_0002908', 'lbl': 'Conjugated hyperbilirubinemia', 'desc': 'label: Conjugated hyperbilirubinemia\ndefinition : \nsynonyms :Direct hyperbilirubinemia\n'}


{'id': 'HP_0002909', 'url': 'http://purl.obolibrary.org/obo/HP_0002909', 'lbl': 'Generalized aminoaciduria', 'desc': 'label: Generalized aminoaciduria\ndefinition : An increased concentration of all types of amino acid in the urine.\nsynonyms :Generalised aminoaciduria; Generalised nonspecific aminoaciduria; Generalized nonspecific aminoaciduria\n'}


{'id': 'HP_0002910', 'url': 'http://purl.obolibrary.org/obo/HP_0002910', 'lbl': 'Elevated hepatic transaminase', 'desc': 'label: Elevated hepatic transaminase\ndefinition : Elevations of the levels of SGOT and SGPT in the serum. SGOT (serum glutamic oxaloacetic transaminase) and SGPT (serum glutamic pyruvic transaminase) are transaminases primarily found in the liver and heart and are released into the bloodstream as the result of liver or heart damage. SGOT and SGPT are used clinically mainly as markers of liver damage.\nsynonyms :Abnormal liver enzymes; Abnormal liver function; Abnormal liver function tests; Elevated liver enzymes; Elevated serum transaminases; Elevated transaminases; High liver enzymes; Increased liver enzymes; Increased liver function tests; Increased transaminases; Raised liver enzymes; Subclinical abnormal liver function tests; Elevated liver function tests\n'}


{'id': 'HP_0002912', 'url': 'http://purl.obolibrary.org/obo/HP_0002912', 'lbl': 'Methylmalonic acidemia', 'desc': 'label: Methylmalonic acidemia\ndefinition : Increased concentration of methylmalonic acid in the blood.\nsynonyms :Elevated circulating methylmalonic acid concentration\n'}


{'id': 'HP_0002913', 'url': 'http://purl.obolibrary.org/obo/HP_0002913', 'lbl': 'Myoglobinuria', 'desc': 'label: Myoglobinuria\ndefinition : Presence of myoglobin in the urine.\nsynonyms :\n'}


{'id': 'HP_0002914', 'url': 'http://purl.obolibrary.org/obo/HP_0002914', 'lbl': 'Hyperchloriduria', 'desc': 'label: Hyperchloriduria\ndefinition : An increased concentration of chloride in the urine.\nsynonyms :Increased urinary chloride\n'}


{'id': 'HP_0002916', 'url': 'http://purl.obolibrary.org/obo/HP_0002916', 'lbl': 'Abnormality of chromosome segregation', 'desc': 'label: Abnormality of chromosome segregation\ndefinition : An abnormality of chromosome segregation.\nsynonyms :\n'}


{'id': 'HP_0002917', 'url': 'http://purl.obolibrary.org/obo/HP_0002917', 'lbl': 'Hypomagnesemia', 'desc': 'label: Hypomagnesemia\ndefinition : An abnormally decreased magnesium concentration in the blood.\nsynonyms :Low blood Mg levels; Low blood magnesium levels\n'}


{'id': 'HP_0002918', 'url': 'http://purl.obolibrary.org/obo/HP_0002918', 'lbl': 'Hypermagnesemia', 'desc': 'label: Hypermagnesemia\ndefinition : An abnormally increased magnesium concentration in the blood.\nsynonyms :High blood Mg levels; High blood magnesium levels\n'}


{'id': 'HP_0002919', 'url': 'http://purl.obolibrary.org/obo/HP_0002919', 'lbl': 'Ketonuria', 'desc': 'label: Ketonuria\ndefinition : High levels of ketone bodies (acetoacetic acid, beta-hydroxybutyric acid, and acetone) in the urine. Ketone bodies are insignificant in the blood and urine of normal individuals in the postprandial or overnight-fasted state.\nsynonyms :Ketonaciduria; Ketone bodies in urine; Acetonuria; Ketoaciduria\n'}


{'id': 'HP_0002920', 'url': 'http://purl.obolibrary.org/obo/HP_0002920', 'lbl': 'Decreased circulating ACTH level', 'desc': 'label: Decreased circulating ACTH level\ndefinition : An abnormal reduction in the concentration of corticotropin, also known as adrenocorticotropic hormone (ACTH), in the blood.\nsynonyms :\n'}


{'id': 'HP_0002921', 'url': 'http://purl.obolibrary.org/obo/HP_0002921', 'lbl': 'Abnormal cerebrospinal fluid morphology', 'desc': 'label: Abnormal cerebrospinal fluid morphology\ndefinition : An abnormality of the cerebrospinal fluid (CSF).\nsynonyms :Abnormal CSF findings; Abnormality of the CSF; Abnormality of the cerebrospinal fluid\n'}


{'id': 'HP_0002922', 'url': 'http://purl.obolibrary.org/obo/HP_0002922', 'lbl': 'Increased CSF protein concentration', 'desc': 'label: Increased CSF protein concentration\ndefinition : Increased concentration of protein in the cerebrospinal fluid.\nsynonyms :Cerebrospinal fluid protein increased; Cerebrospinal fluid with increased protein; Elevated cerebrospinal fluid protein; Elevated csf protein; Hyperproteinorrhachia; Increased CSF protein; Increased protein in csf; Spinal fluid protein elevated\n'}


{'id': 'HP_0002923', 'url': 'http://purl.obolibrary.org/obo/HP_0002923', 'lbl': 'Rheumatoid factor positive', 'desc': 'label: Rheumatoid factor positive\ndefinition : The presence in the serum of an autoantibody directed against the Fc portion of IgG.\nsynonyms :\n'}


{'id': 'HP_0002924', 'url': 'http://purl.obolibrary.org/obo/HP_0002924', 'lbl': 'obsolete Decreased circulating aldosterone level', 'desc': 'label: obsolete Decreased circulating aldosterone level\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002925', 'url': 'http://purl.obolibrary.org/obo/HP_0002925', 'lbl': 'Elevated circulating thyroid-stimulating hormone concentration', 'desc': 'label: Elevated circulating thyroid-stimulating hormone concentration\ndefinition : Increased concentration of thyroid-stimulating hormone (TSH) in the blood circulation.\nsynonyms :Elevated thyroid stimulating hormone; Elevated thyroid stimulating hormone levels; High TSH; Increased serum thyroid-stimulating hormone; Increased thyroid-stimulating hormone; Increased thyroid-stimulating hormone level; Increased thyrotropin level; TSH excess; Thyroid-stimulating hormone excess\n'}


{'id': 'HP_0002926', 'url': 'http://purl.obolibrary.org/obo/HP_0002926', 'lbl': 'Abnormality of thyroid physiology', 'desc': 'label: Abnormality of thyroid physiology\ndefinition : An abnormal functionality of the thyroid gland.\nsynonyms :Abnormal thyroid function\n'}


{'id': 'HP_0002927', 'url': 'http://purl.obolibrary.org/obo/HP_0002927', 'lbl': 'Histidinuria', 'desc': 'label: Histidinuria\ndefinition : An increased concentration of histidine in the urine.\nsynonyms :Elevated histidine in urine; High urine histidine levels\n'}


{'id': 'HP_0002928', 'url': 'http://purl.obolibrary.org/obo/HP_0002928', 'lbl': 'Decreased activity of the pyruvate dehydrogenase complex', 'desc': 'label: Decreased activity of the pyruvate dehydrogenase complex\ndefinition : \nsynonyms :Decreased activity of the PDH complex; Pyruvate dehydrogenase complex deficiency\n'}


{'id': 'HP_0002929', 'url': 'http://purl.obolibrary.org/obo/HP_0002929', 'lbl': 'Leydig cell insensitivity to gonadotropin', 'desc': 'label: Leydig cell insensitivity to gonadotropin\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002930', 'url': 'http://purl.obolibrary.org/obo/HP_0002930', 'lbl': 'Impaired sensitivity to thyroid hormone', 'desc': 'label: Impaired sensitivity to thyroid hormone\ndefinition : Reduced sensitivity of end organs to thyroid hormone characterized by elevated serum levels of free thyroid hormone with nonsuppressed thyroid stimulating hormone.\nsynonyms :Elevated serum levels of free thyroid hormone with nonsuppressed TSH; End-organ unresponsiveness to thyroid hormone; Resistance to thyroid hormone; Thyroid hormone receptor defect; Thyroid hormone resistance\n'}


{'id': 'HP_0002932', 'url': 'http://purl.obolibrary.org/obo/HP_0002932', 'lbl': 'Aldehyde oxidase deficiency', 'desc': 'label: Aldehyde oxidase deficiency\ndefinition : A reduction in aldehyde oxidase level.\nsynonyms :\n'}


{'id': 'HP_0002933', 'url': 'http://purl.obolibrary.org/obo/HP_0002933', 'lbl': 'Ventral hernia', 'desc': 'label: Ventral hernia\ndefinition : Ventral hernia refers to a condition in which abdominal contents protrude through a weakened portion of the abdominal wall.\nsynonyms :\n'}


{'id': 'HP_0002936', 'url': 'http://purl.obolibrary.org/obo/HP_0002936', 'lbl': 'Distal sensory impairment', 'desc': 'label: Distal sensory impairment\ndefinition : An abnormal reduction in sensation in the distal portions of the extremities.\nsynonyms :Decreased distal sensation; Decreased sensation in extremities; Distal sensation loss; Distal sensory impairment in lower limbs; Distal sensory impairment of the lower extremities; Distal sensory loss; Distal sensory loss, upper and lower limbs; Loss of distal sensation\n'}


{'id': 'HP_0002937', 'url': 'http://purl.obolibrary.org/obo/HP_0002937', 'lbl': 'Hemivertebrae', 'desc': 'label: Hemivertebrae\ndefinition : Absence of one half of the vertebral body.\nsynonyms :Hemi-vertebrae; Hemivertebra; Missing part of vertebrae\n'}


{'id': 'HP_0002938', 'url': 'http://purl.obolibrary.org/obo/HP_0002938', 'lbl': 'Lumbar hyperlordosis', 'desc': 'label: Lumbar hyperlordosis\ndefinition : An abnormal accentuation of the inward curvature of the spine in the lumbar region.\nsynonyms :Exaggerated lumbar lordosis; Excessive inward curvature of lower spine; Increased lumbar lordosis; Lumbar lordosis; Prominent lumbar lordosis\n'}


{'id': 'HP_0002942', 'url': 'http://purl.obolibrary.org/obo/HP_0002942', 'lbl': 'Thoracic kyphosis', 'desc': 'label: Thoracic kyphosis\ndefinition : Over curvature of the thoracic region, leading to a round back or if sever to a hump.\nsynonyms :Accentuated thoracic kyphosis; Exaggerated thoracic kyphosis\n'}


{'id': 'HP_0002943', 'url': 'http://purl.obolibrary.org/obo/HP_0002943', 'lbl': 'Thoracic scoliosis', 'desc': 'label: Thoracic scoliosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002944', 'url': 'http://purl.obolibrary.org/obo/HP_0002944', 'lbl': 'Thoracolumbar scoliosis', 'desc': 'label: Thoracolumbar scoliosis\ndefinition : \nsynonyms :Scoliosis, thoracolumbar\n'}


{'id': 'HP_0002945', 'url': 'http://purl.obolibrary.org/obo/HP_0002945', 'lbl': 'Intervertebral space narrowing', 'desc': 'label: Intervertebral space narrowing\ndefinition : Decreased height of the intervertebral disk.\nsynonyms :Narrow intervertebral disc spaces; Narrow intervertebral spaces\n'}


{'id': 'HP_0002946', 'url': 'http://purl.obolibrary.org/obo/HP_0002946', 'lbl': 'Supernumerary vertebrae', 'desc': 'label: Supernumerary vertebrae\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002947', 'url': 'http://purl.obolibrary.org/obo/HP_0002947', 'lbl': 'Cervical kyphosis', 'desc': 'label: Cervical kyphosis\ndefinition : Exaggerated convexity of the cervical vertebral column, causing the cervical spine to bow outwards and take on a rounded appearance.\nsynonyms :Rounded neck\n'}


{'id': 'HP_0002948', 'url': 'http://purl.obolibrary.org/obo/HP_0002948', 'lbl': 'Vertebral fusion', 'desc': 'label: Vertebral fusion\ndefinition : A developmental defect leading to the union of two adjacent vertebrae.\nsynonyms :Fused vertebrae; Fusion of vertebral bodies; Spinal fusion; Vertebral body fusion\n'}


{'id': 'HP_0002949', 'url': 'http://purl.obolibrary.org/obo/HP_0002949', 'lbl': 'Fused cervical vertebrae', 'desc': 'label: Fused cervical vertebrae\ndefinition : A congenital anomaly characterized by a joining (fusion) of two or more cervical vertebral bodies with one another.\nsynonyms :Cervical spine fusion; Cervical vertebral fusion; Fused neck; Fusion of cervical vertebrae\n'}


{'id': 'HP_0002951', 'url': 'http://purl.obolibrary.org/obo/HP_0002951', 'lbl': 'Partial absence of cerebellar vermis', 'desc': 'label: Partial absence of cerebellar vermis\ndefinition : Congenital absence of a part of the vermis of cerebellum.\nsynonyms :\n'}


{'id': 'HP_0002953', 'url': 'http://purl.obolibrary.org/obo/HP_0002953', 'lbl': 'Vertebral compression fracture', 'desc': 'label: Vertebral compression fracture\ndefinition : \nsynonyms :Compression fracture of a vertebral body; Fractures of vertebral bodies; Vertebral body compression; Vertebral collapse; Vertebral compression; Vertebral compression fractures; Vertebral compression or collapse\n'}


{'id': 'HP_0002955', 'url': 'http://purl.obolibrary.org/obo/HP_0002955', 'lbl': 'Granulomatosis', 'desc': 'label: Granulomatosis\ndefinition : A granulomatous inflammation leading to multiple granuloma formation, which is a specific type of inflammation. A granuloma is a focal compact collection of inflammatory cells, mononuclear cells predominating, usually as a result of the persistence of a non-degradable product and of active cell mediated hypersensitivity.\nsynonyms :\n'}


{'id': 'HP_0002958', 'url': 'http://purl.obolibrary.org/obo/HP_0002958', 'lbl': 'Immune dysregulation', 'desc': 'label: Immune dysregulation\ndefinition : Altered immune function characterized by lymphoid proliferation, immune activation, and excessive autoreactivity often leading to autoimmune/inflammatory complications.\nsynonyms :Immune dysregulation; Unregulated immune response\n'}


{'id': 'HP_0002959', 'url': 'http://purl.obolibrary.org/obo/HP_0002959', 'lbl': 'Impaired Ig class switch recombination', 'desc': 'label: Impaired Ig class switch recombination\ndefinition : An impairment of the class-switch recombination process that normally leads B lymphocytes to produce IgG, IgA, or IgE.\nsynonyms :Impaired B-lymphocyte isotype switching\n'}


{'id': 'HP_0002960', 'url': 'http://purl.obolibrary.org/obo/HP_0002960', 'lbl': 'Autoimmunity', 'desc': "label: Autoimmunity\ndefinition : The occurrence of an immune reaction against the organism's own cells or tissues.\nsynonyms :Autoimmune condition; Autoimmune disease; Autoimmune disorder; Autoimmunity\n"}


{'id': 'HP_0002961', 'url': 'http://purl.obolibrary.org/obo/HP_0002961', 'lbl': 'Dysgammaglobulinemia', 'desc': 'label: Dysgammaglobulinemia\ndefinition : Selective deficiency of one or more, but not all, classes of immunoglobulins.\nsynonyms :\n'}


{'id': 'HP_0002963', 'url': 'http://purl.obolibrary.org/obo/HP_0002963', 'lbl': 'Abnormal delayed hypersensitivity skin test', 'desc': 'label: Abnormal delayed hypersensitivity skin test\ndefinition : Delay in cutaneous immune reaction to specific antigens mediated not by antibodies but by cells. The delayed hypersensitivity test is an immune function test measuring the presence of activated T cells that recognize a specific antigen and is performed by injecting a small amount of the antigen into the skin. The area of the injection is examined 48-72 hours thereafter.\nsynonyms :\n'}


{'id': 'HP_0002965', 'url': 'http://purl.obolibrary.org/obo/HP_0002965', 'lbl': 'Cutaneous anergy', 'desc': 'label: Cutaneous anergy\ndefinition : Inability to react to a delayed hypersensitivity skin test.\nsynonyms :Absence of delayed hypersensitivity skin test; Lack of delayed skin hypersensitivity reaction\n'}


{'id': 'HP_0002967', 'url': 'http://purl.obolibrary.org/obo/HP_0002967', 'lbl': 'Cubitus valgus', 'desc': 'label: Cubitus valgus\ndefinition : Abnormal positioning in which the elbows are turned out.\nsynonyms :Outward turned elbows\n'}


{'id': 'HP_0002970', 'url': 'http://purl.obolibrary.org/obo/HP_0002970', 'lbl': 'Genu varum', 'desc': 'label: Genu varum\ndefinition : A positional abnormality marked by outward bowing of the legs in which the knees stay wide apart when a person stands with the feet and ankles together.\nsynonyms :Genu vara; Genua vara; Outward bow-leggedness; Outward bowing at knees\n'}


{'id': 'HP_0002971', 'url': 'http://purl.obolibrary.org/obo/HP_0002971', 'lbl': 'Absent microvilli on the surface of peripheral blood lymphocytes', 'desc': 'label: Absent microvilli on the surface of peripheral blood lymphocytes\ndefinition : Absence of the fingerlike protrusive, actin-dependent structures found on the surface of peripheral blood lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0002972', 'url': 'http://purl.obolibrary.org/obo/HP_0002972', 'lbl': 'Reduced delayed hypersensitivity', 'desc': 'label: Reduced delayed hypersensitivity\ndefinition : Decreased ability to react to a delayed hypersensitivity skin test.\nsynonyms :Decreased reactivity to skin test antigens; Deficiency of delayed skin hypersensitivity; Impaired delayed hypersensitivity\n'}


{'id': 'HP_0002973', 'url': 'http://purl.obolibrary.org/obo/HP_0002973', 'lbl': 'Abnormal forearm morphology', 'desc': 'label: Abnormal forearm morphology\ndefinition : An abnormality of the lower arm.\nsynonyms :Abnormality of the forearm\n'}


{'id': 'HP_0002974', 'url': 'http://purl.obolibrary.org/obo/HP_0002974', 'lbl': 'Radioulnar synostosis', 'desc': 'label: Radioulnar synostosis\ndefinition : An abnormal osseous union (fusion) between the radius and the ulna.\nsynonyms :Fused forearm bones\n'}


{'id': 'HP_0002977', 'url': 'http://purl.obolibrary.org/obo/HP_0002977', 'lbl': 'Aplasia/Hypoplasia involving the central nervous system', 'desc': 'label: Aplasia/Hypoplasia involving the central nervous system\ndefinition : Absence or underdevelopment of tissue in the central nervous system.\nsynonyms :Absent/underdeveloped central nervous system tissue; Aplasia/Hypoplasia involving the CNS\n'}


{'id': 'HP_0002979', 'url': 'http://purl.obolibrary.org/obo/HP_0002979', 'lbl': 'Bowing of the legs', 'desc': 'label: Bowing of the legs\ndefinition : A bending or abnormal curvature affecting a long bone of the leg.\nsynonyms :Bow legs; Bow-leggedness; Bowed legs; Bowed lower limbs\n'}


{'id': 'HP_0002980', 'url': 'http://purl.obolibrary.org/obo/HP_0002980', 'lbl': 'Femoral bowing', 'desc': 'label: Femoral bowing\ndefinition : Bowing (abnormal curvature) of the femur.\nsynonyms :Bowed femur; Bowed femura; Bowed femurs; Bowed thighbone\n'}


{'id': 'HP_0002981', 'url': 'http://purl.obolibrary.org/obo/HP_0002981', 'lbl': 'Abnormality of the calf', 'desc': 'label: Abnormality of the calf\ndefinition : An abnormality of the calf, i.e. of the posterior part of the lower leg.\nsynonyms :Abnormality of the calf\n'}


{'id': 'HP_0002982', 'url': 'http://purl.obolibrary.org/obo/HP_0002982', 'lbl': 'Tibial bowing', 'desc': 'label: Tibial bowing\ndefinition : A bending or abnormal curvature of the tibia.\nsynonyms :Bowed shankbone; Bowed shinbone; Bowed tibia; Bowing of the tibia\n'}


{'id': 'HP_0002983', 'url': 'http://purl.obolibrary.org/obo/HP_0002983', 'lbl': 'Micromelia', 'desc': 'label: Micromelia\ndefinition : The presence of abnormally small extremities.\nsynonyms :Smaller or shorter than typical limbs\n'}


{'id': 'HP_0002984', 'url': 'http://purl.obolibrary.org/obo/HP_0002984', 'lbl': 'Hypoplasia of the radius', 'desc': 'label: Hypoplasia of the radius\ndefinition : Underdevelopment of the radius.\nsynonyms :Hypoplastic radii; Hypoplastic radius; Radial hypoplasia; Short radii; Short radius; Shortening of radius; Underdeveloped outer large forearm bone; Radial ray hypoplasia\n'}


{'id': 'HP_0002986', 'url': 'http://purl.obolibrary.org/obo/HP_0002986', 'lbl': 'Radial bowing', 'desc': 'label: Radial bowing\ndefinition : A bending or abnormal curvature of the radius.\nsynonyms :Bowed radii; Bowed radius; Bowing of outer large bone of the forearm; Bowing of radius bone of the forearm\n'}


{'id': 'HP_0002987', 'url': 'http://purl.obolibrary.org/obo/HP_0002987', 'lbl': 'Elbow flexion contracture', 'desc': 'label: Elbow flexion contracture\ndefinition : An elbow contracture that limits the ability of the elbow joint to be extended (straightened), meaning that the elbow is fixed in an flexed (bent) position.\nsynonyms :Elbow flexion contractures; Elbow flexion deformity; Fixed flexion at the elbow joint\n'}


{'id': 'HP_0002990', 'url': 'http://purl.obolibrary.org/obo/HP_0002990', 'lbl': 'Fibular aplasia', 'desc': 'label: Fibular aplasia\ndefinition : Absence of the fibula.\nsynonyms :Absent calf bone; Absent fibulae; Absent-hypoplastic fibulae\n'}


{'id': 'HP_0002991', 'url': 'http://purl.obolibrary.org/obo/HP_0002991', 'lbl': 'Abnormality of fibula morphology', 'desc': 'label: Abnormality of fibula morphology\ndefinition : An anomaly of the calf bone (fibula), one of the two bones of the calf.\nsynonyms :Abnormality of the calf bone\n'}


{'id': 'HP_0002992', 'url': 'http://purl.obolibrary.org/obo/HP_0002992', 'lbl': 'Abnormality of tibia morphology', 'desc': 'label: Abnormality of tibia morphology\ndefinition : Abnormality of the tibia (shinbone).\nsynonyms :Abnormality of the shankbone; Abnormality of the shinbone\n'}


{'id': 'HP_0002996', 'url': 'http://purl.obolibrary.org/obo/HP_0002996', 'lbl': 'Limited elbow movement', 'desc': 'label: Limited elbow movement\ndefinition : \nsynonyms :Decreased elbow mobility; Limited elbow mobility; Limited elbow movement; Restricted elbow motion\n'}


{'id': 'HP_0002997', 'url': 'http://purl.obolibrary.org/obo/HP_0002997', 'lbl': 'obsolete Abnormality of the ulna', 'desc': 'label: obsolete Abnormality of the ulna\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0002999', 'url': 'http://purl.obolibrary.org/obo/HP_0002999', 'lbl': 'Patellar dislocation', 'desc': 'label: Patellar dislocation\ndefinition : The kneecap normally is located within the groove termed trochlea on the distal femur and can slide up and down in it. Patellar dislocation occurs if the patella fully dislocates out of the groove.\nsynonyms :Dislocated kneecap; Dislocated patellae; Dislocation of patella\n'}


{'id': 'HP_0003001', 'url': 'http://purl.obolibrary.org/obo/HP_0003001', 'lbl': 'Glomus jugular tumor', 'desc': 'label: Glomus jugular tumor\ndefinition : \nsynonyms :Glomus jugular tumour; Glomus jugulare tumor; Glomus jugulare tumors; Glomus jugulare tumour; Glomus jugulare tumours\n'}


{'id': 'HP_0003002', 'url': 'http://purl.obolibrary.org/obo/HP_0003002', 'lbl': 'Breast carcinoma', 'desc': 'label: Breast carcinoma\ndefinition : The presence of a carcinoma of the breast.\nsynonyms :Breast cancer\n'}


{'id': 'HP_0003003', 'url': 'http://purl.obolibrary.org/obo/HP_0003003', 'lbl': 'Colon cancer', 'desc': 'label: Colon cancer\ndefinition : \nsynonyms :Colon cancer\n'}


{'id': 'HP_0003005', 'url': 'http://purl.obolibrary.org/obo/HP_0003005', 'lbl': 'Ganglioneuroma', 'desc': 'label: Ganglioneuroma\ndefinition : A benign neoplasm that usually arises from the sympathetic trunk in the mediastinum, representing a tumor of the sympathetic nerve fibers arising from neural crest cells.\nsynonyms :\n'}


{'id': 'HP_0003006', 'url': 'http://purl.obolibrary.org/obo/HP_0003006', 'lbl': 'Neuroblastoma', 'desc': 'label: Neuroblastoma\ndefinition : Neuroblastoma is a solid tumor that originate in neural crest cells of the sympathetic nervous system. Most neuroblastomas originate in the abdomen, and most abdominal neuroblastomas originate in the adrenal gland. Neuroblastomas can also originate in the thorax, usually in the posterior mediastinum.\nsynonyms :Cancer of early nerve cells\n'}


{'id': 'HP_0003009', 'url': 'http://purl.obolibrary.org/obo/HP_0003009', 'lbl': 'Enhanced neurotoxicity of vincristine', 'desc': 'label: Enhanced neurotoxicity of vincristine\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003010', 'url': 'http://purl.obolibrary.org/obo/HP_0003010', 'lbl': 'Prolonged bleeding time', 'desc': 'label: Prolonged bleeding time\ndefinition : Prolongation of the time taken for a standardized skin cut of fixed depth and length to stop bleeding.\nsynonyms :Increased bleeding time; Prolonged bleeding time\n'}


{'id': 'HP_0003011', 'url': 'http://purl.obolibrary.org/obo/HP_0003011', 'lbl': 'Abnormality of the musculature', 'desc': 'label: Abnormality of the musculature\ndefinition : Abnormality originating in one or more muscles, i.e., of the set of muscles of body.\nsynonyms :Muscular abnormality\n'}


{'id': 'HP_0003013', 'url': 'http://purl.obolibrary.org/obo/HP_0003013', 'lbl': 'Bulging epiphyses', 'desc': 'label: Bulging epiphyses\ndefinition : A morphological abnormality of epiphyses whereby they are abnormally outwardly curving (protuberant).\nsynonyms :Bulging end part of bone\n'}


{'id': 'HP_0003015', 'url': 'http://purl.obolibrary.org/obo/HP_0003015', 'lbl': 'Flared metaphysis', 'desc': 'label: Flared metaphysis\ndefinition : The presence of a splayed (i.e.,flared) metaphyseal segment of one or more long bones.\nsynonyms :Flared wide portion of long bone; Flared, widened metaphyses; Metaphyseal flaring; Metaphyseal flaring of long bones; Metaphyseal splaying; Metaphyses flared; Splayed metaphyses; marked metaphyseal flaring of long bones\n'}


{'id': 'HP_0003016', 'url': 'http://purl.obolibrary.org/obo/HP_0003016', 'lbl': 'Metaphyseal widening', 'desc': 'label: Metaphyseal widening\ndefinition : Abnormal widening of the metaphyseal regions of long bones.\nsynonyms :Broad wide portion of long bone; Wide metaphyses; Widened long bone metaphyses; Widened metaphyses\n'}


{'id': 'HP_0003019', 'url': 'http://purl.obolibrary.org/obo/HP_0003019', 'lbl': 'Abnormality of the wrist', 'desc': 'label: Abnormality of the wrist\ndefinition : Abnormality of the wrist, the structure connecting the hand and the forearm.\nsynonyms :Abnormalities of the wrists; Abnormality of the wrist\n'}


{'id': 'HP_0003020', 'url': 'http://purl.obolibrary.org/obo/HP_0003020', 'lbl': 'Enlargement of the wrists', 'desc': 'label: Enlargement of the wrists\ndefinition : \nsynonyms :Enlargement of the wrists\n'}


{'id': 'HP_0003021', 'url': 'http://purl.obolibrary.org/obo/HP_0003021', 'lbl': 'Metaphyseal cupping', 'desc': 'label: Metaphyseal cupping\ndefinition : Metaphyseal cupping refers to an inward bulging of the metaphyseal profile giving the metaphysis a cup-like appearance.\nsynonyms :\n'}


{'id': 'HP_0003022', 'url': 'http://purl.obolibrary.org/obo/HP_0003022', 'lbl': 'Hypoplasia of the ulna', 'desc': 'label: Hypoplasia of the ulna\ndefinition : Underdevelopment of the ulna.\nsynonyms :Hypoplastic ulna; Short ulna; Short ulnae; Ulnar hypoplasia; Underdeveloped inner large forearm bone; Underdeveloped ulna\n'}


{'id': 'HP_0003023', 'url': 'http://purl.obolibrary.org/obo/HP_0003023', 'lbl': 'Bowing of limbs due to multiple fractures', 'desc': 'label: Bowing of limbs due to multiple fractures\ndefinition : Curvature of the shafts of the long bones due to multiple fractures.\nsynonyms :Bowed limbs due to multiple fractures\n'}


{'id': 'HP_0003025', 'url': 'http://purl.obolibrary.org/obo/HP_0003025', 'lbl': 'Metaphyseal irregularity', 'desc': 'label: Metaphyseal irregularity\ndefinition : Irregularity of the normally smooth surface of the metaphyses.\nsynonyms :Frayed, irregular metaphyses; Frayed, irregular, metaphyses; Irregular metaphyses; Irregular wide portion of a long bone; Metaphyseal fraying; Metaphyseal irregularities\n'}


{'id': 'HP_0003026', 'url': 'http://purl.obolibrary.org/obo/HP_0003026', 'lbl': 'Short long bone', 'desc': 'label: Short long bone\ndefinition : One or more abnormally short long bone.\nsynonyms :Long bone shortening; Short long bone; Short tubular bones; shortened long tubular bones\n'}


{'id': 'HP_0003027', 'url': 'http://purl.obolibrary.org/obo/HP_0003027', 'lbl': 'Mesomelia', 'desc': 'label: Mesomelia\ndefinition : Shortening of the middle parts of the limbs (forearm and lower leg) in relation to the upper and terminal segments.\nsynonyms :Disproportionately short middle portion of limb; Mesomelic limb shortening; Mesomelic shortening of limbs; Symmetric mesomelic limb shortness\n'}


{'id': 'HP_0003028', 'url': 'http://purl.obolibrary.org/obo/HP_0003028', 'lbl': 'Abnormality of the ankle', 'desc': 'label: Abnormality of the ankle\ndefinition : An anomaly of the joint that connects the foot with the leg.\nsynonyms :Abnormality of the ankles\n'}


{'id': 'HP_0003029', 'url': 'http://purl.obolibrary.org/obo/HP_0003029', 'lbl': 'Enlargement of the ankles', 'desc': 'label: Enlargement of the ankles\ndefinition : \nsynonyms :Enlargement of the ankles\n'}


{'id': 'HP_0003031', 'url': 'http://purl.obolibrary.org/obo/HP_0003031', 'lbl': 'Ulnar bowing', 'desc': 'label: Ulnar bowing\ndefinition : Bending of the diaphysis (shaft) of the ulna.\nsynonyms :Bowed ulna; Curved ulna; Curving of inner forearm bone\n'}


{'id': 'HP_0003034', 'url': 'http://purl.obolibrary.org/obo/HP_0003034', 'lbl': 'Diaphyseal sclerosis', 'desc': 'label: Diaphyseal sclerosis\ndefinition : An elevation in bone density in one or more diaphyses. Sclerosis is normally detected on a radiograph as an area of increased opacity.\nsynonyms :Craniodiaphyseal osteosclerosis; Diaphyseal osteosclerosis; Increased bone density in shaft of long bone\n'}


{'id': 'HP_0003037', 'url': 'http://purl.obolibrary.org/obo/HP_0003037', 'lbl': 'Enlarged joints', 'desc': 'label: Enlarged joints\ndefinition : Increase in size of one or more joints.\nsynonyms :Enlarged joints; Prominent joints\n'}


{'id': 'HP_0003038', 'url': 'http://purl.obolibrary.org/obo/HP_0003038', 'lbl': 'Fibular hypoplasia', 'desc': 'label: Fibular hypoplasia\ndefinition : Underdevelopment of the fibula.\nsynonyms :Hypoplastic fibula; Short calf bone; Short fibula; Short fibulae\n'}


{'id': 'HP_0003040', 'url': 'http://purl.obolibrary.org/obo/HP_0003040', 'lbl': 'Arthropathy', 'desc': 'label: Arthropathy\ndefinition : \nsynonyms :Disease of the joints\n'}


{'id': 'HP_0003041', 'url': 'http://purl.obolibrary.org/obo/HP_0003041', 'lbl': 'Humeroradial synostosis', 'desc': 'label: Humeroradial synostosis\ndefinition : An abnormal osseous union (fusion) between the radius and the humerus.\nsynonyms :Fusion of upper and lower arm bones; Humeral radial synostosis; Humeral-radial synostosis; Radiohumeral synostosis of elbow; Synostosis of radius and humerus\n'}


{'id': 'HP_0003042', 'url': 'http://purl.obolibrary.org/obo/HP_0003042', 'lbl': 'Elbow dislocation', 'desc': 'label: Elbow dislocation\ndefinition : Dislocation of the distal humerus out of the elbow joint, where the radius, ulna, and humerus meet.\nsynonyms :Dislocations of the elbows; Elbow dislocation; Elbow dislocations; Radiocapitellar dislocation; Radiohumeral dislocation; Ulnohumeral dislocation\n'}


{'id': 'HP_0003043', 'url': 'http://purl.obolibrary.org/obo/HP_0003043', 'lbl': 'Abnormal shoulder morphology', 'desc': 'label: Abnormal shoulder morphology\ndefinition : An abnormality of the shoulder, which is defined as the structures surrounding the shoulder joint where the humerus attaches to the scapula.\nsynonyms :Abnormality of the shoulder\n'}


{'id': 'HP_0003044', 'url': 'http://purl.obolibrary.org/obo/HP_0003044', 'lbl': 'Shoulder flexion contracture', 'desc': 'label: Shoulder flexion contracture\ndefinition : Chronic reduction in active and passive mobility of the shoulder joint due to structural changes in muscle, tendons, ligaments, or skin that prevents normal movement.\nsynonyms :\n'}


{'id': 'HP_0003045', 'url': 'http://purl.obolibrary.org/obo/HP_0003045', 'lbl': 'Abnormal patella morphology', 'desc': 'label: Abnormal patella morphology\ndefinition : Abnormality of the patella (knee cap).\nsynonyms :Abnormal kneecap; Abnormality of the patella; Patellar abnormality\n'}


{'id': 'HP_0003048', 'url': 'http://purl.obolibrary.org/obo/HP_0003048', 'lbl': 'Radial head subluxation', 'desc': 'label: Radial head subluxation\ndefinition : Partial dislocation of the head of the radius.\nsynonyms :Radial subluxation; Radial-head subluxation\n'}


{'id': 'HP_0003049', 'url': 'http://purl.obolibrary.org/obo/HP_0003049', 'lbl': 'Ulnar deviation of the wrist', 'desc': 'label: Ulnar deviation of the wrist\ndefinition : \nsynonyms :Ulnar deviation of wrists\n'}


{'id': 'HP_0003051', 'url': 'http://purl.obolibrary.org/obo/HP_0003051', 'lbl': 'Enlarged metaphyses', 'desc': 'label: Enlarged metaphyses\ndefinition : Abnormal increase in size of one or more metaphyses.\nsynonyms :Enlarged wide portion of a long bone\n'}


{'id': 'HP_0003053', 'url': 'http://purl.obolibrary.org/obo/HP_0003053', 'lbl': 'Epiphyseal deformities of tubular bones', 'desc': 'label: Epiphyseal deformities of tubular bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003057', 'url': 'http://purl.obolibrary.org/obo/HP_0003057', 'lbl': 'Tetraamelia', 'desc': 'label: Tetraamelia\ndefinition : Amelia of all four limbs.\nsynonyms :Tetra-amelia\n'}


{'id': 'HP_0003059', 'url': 'http://purl.obolibrary.org/obo/HP_0003059', 'lbl': 'Abnormality of the radioulnar joints', 'desc': 'label: Abnormality of the radioulnar joints\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003063', 'url': 'http://purl.obolibrary.org/obo/HP_0003063', 'lbl': 'Abnormality of the humerus', 'desc': 'label: Abnormality of the humerus\ndefinition : An abnormality of the humerus (i.e., upper arm bone).\nsynonyms :Abnormality of the humeri\n'}


{'id': 'HP_0003065', 'url': 'http://purl.obolibrary.org/obo/HP_0003065', 'lbl': 'Patellar hypoplasia', 'desc': 'label: Patellar hypoplasia\ndefinition : Underdevelopment of the patella.\nsynonyms :Hypoplastic patellae; Small kneecap; Small patella; Small patellae; Underdeveloped kneecap\n'}


{'id': 'HP_0003066', 'url': 'http://purl.obolibrary.org/obo/HP_0003066', 'lbl': 'Limited knee extension', 'desc': 'label: Limited knee extension\ndefinition : Reduced ability to extend (straighten) the knee joint.\nsynonyms :Limited knee extension\n'}


{'id': 'HP_0003067', 'url': 'http://purl.obolibrary.org/obo/HP_0003067', 'lbl': 'Madelung deformity', 'desc': 'label: Madelung deformity\ndefinition : An anomaly related to partial closure, or failure of development of the ulnar side of the distal radial growth plate, which results in an arrest of epiphyseal growth of the medial and volar portions of the distal radius. This leads to shortening of the radius and relative overgrowth of the ulna.\nsynonyms :Madelung wrist deformity\n'}


{'id': 'HP_0003068', 'url': 'http://purl.obolibrary.org/obo/HP_0003068', 'lbl': 'Madelung-like forearm deformities', 'desc': 'label: Madelung-like forearm deformities\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003070', 'url': 'http://purl.obolibrary.org/obo/HP_0003070', 'lbl': 'Elbow ankylosis', 'desc': 'label: Elbow ankylosis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003071', 'url': 'http://purl.obolibrary.org/obo/HP_0003071', 'lbl': 'Flattened epiphysis', 'desc': 'label: Flattened epiphysis\ndefinition : Abnormal flatness (decreased height) of epiphyses.\nsynonyms :Flat end part of bone; Flat epiphyses\n'}


{'id': 'HP_0003072', 'url': 'http://purl.obolibrary.org/obo/HP_0003072', 'lbl': 'Hypercalcemia', 'desc': 'label: Hypercalcemia\ndefinition : An abnormally increased calcium concentration in the blood.\nsynonyms :High blood calcium levels; Hypercalcaemia; Increased calcium in blood\n'}


{'id': 'HP_0003073', 'url': 'http://purl.obolibrary.org/obo/HP_0003073', 'lbl': 'Hypoalbuminemia', 'desc': 'label: Hypoalbuminemia\ndefinition : Reduction in the concentration of albumin in the blood.\nsynonyms :Low albumin; Hypoalbuminaemia; Low blood albumin\n'}


{'id': 'HP_0003074', 'url': 'http://purl.obolibrary.org/obo/HP_0003074', 'lbl': 'Hyperglycemia', 'desc': 'label: Hyperglycemia\ndefinition : An increased concentration of glucose in the blood.\nsynonyms :High blood glucose; High blood sugar\n'}


{'id': 'HP_0003075', 'url': 'http://purl.obolibrary.org/obo/HP_0003075', 'lbl': 'Hypoproteinemia', 'desc': 'label: Hypoproteinemia\ndefinition : A decreased concentration of protein in the blood.\nsynonyms :Decreased protein levels in blood\n'}


{'id': 'HP_0003076', 'url': 'http://purl.obolibrary.org/obo/HP_0003076', 'lbl': 'Glycosuria', 'desc': 'label: Glycosuria\ndefinition : An increased concentration of glucose in the urine.\nsynonyms :Glucose in urine; Glucosuria\n'}


{'id': 'HP_0003077', 'url': 'http://purl.obolibrary.org/obo/HP_0003077', 'lbl': 'Hyperlipidemia', 'desc': 'label: Hyperlipidemia\ndefinition : An elevated lipid concentration in the blood.\nsynonyms :Elevated lipids in blood\n'}


{'id': 'HP_0003079', 'url': 'http://purl.obolibrary.org/obo/HP_0003079', 'lbl': 'Defective DNA repair after ultraviolet radiation damage', 'desc': 'label: Defective DNA repair after ultraviolet radiation damage\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003080', 'url': 'http://purl.obolibrary.org/obo/HP_0003080', 'lbl': 'Hydroxyprolinuria', 'desc': 'label: Hydroxyprolinuria\ndefinition : An increased concentration of 4-hydroxy-L-proline in the urine.\nsynonyms :Elevated urinary hydroxyproline\n'}


{'id': 'HP_0003081', 'url': 'http://purl.obolibrary.org/obo/HP_0003081', 'lbl': 'Increased urinary potassium', 'desc': 'label: Increased urinary potassium\ndefinition : An increased concentration of potassium(1+) in the urine.\nsynonyms :Hyperkaliuresis; Increased urinary K; Increased urinary potassium\n'}


{'id': 'HP_0003083', 'url': 'http://purl.obolibrary.org/obo/HP_0003083', 'lbl': 'Dislocated radial head', 'desc': 'label: Dislocated radial head\ndefinition : A dislocation of the head of the radius from its socket in the elbow joint.\nsynonyms :Congenital radial head dislocation; Dislocated radius; Dislocation of radial head; Dislocation of the radial head; Radial dislocation; Radial head dislocation; Radial head dislocation/subluxation; Dislocated radial heads\n'}


{'id': 'HP_0003084', 'url': 'http://purl.obolibrary.org/obo/HP_0003084', 'lbl': 'Fractures of the long bones', 'desc': 'label: Fractures of the long bones\ndefinition : An increased tendency to fractures of the long bones (Mainly, the femur, tibia, fibula, humerus, radius, and ulna).\nsynonyms :Increased long bone fracture rate\n'}


{'id': 'HP_0003085', 'url': 'http://purl.obolibrary.org/obo/HP_0003085', 'lbl': 'Long fibula', 'desc': 'label: Long fibula\ndefinition : Disproportionately long fibulae.\nsynonyms :Disproportionately long fibula; Long calf bone; Long fibula\n'}


{'id': 'HP_0003086', 'url': 'http://purl.obolibrary.org/obo/HP_0003086', 'lbl': 'Acromesomelia', 'desc': 'label: Acromesomelia\ndefinition : Small hands and feet.\nsynonyms :\n'}


{'id': 'HP_0003088', 'url': 'http://purl.obolibrary.org/obo/HP_0003088', 'lbl': 'Premature osteoarthritis', 'desc': 'label: Premature osteoarthritis\ndefinition : \nsynonyms :Premature arthritis; Premature osteoarthritis\n'}


{'id': 'HP_0003089', 'url': 'http://purl.obolibrary.org/obo/HP_0003089', 'lbl': 'Hamstring contractures', 'desc': 'label: Hamstring contractures\ndefinition : \nsynonyms :Hamstring contractures\n'}


{'id': 'HP_0003090', 'url': 'http://purl.obolibrary.org/obo/HP_0003090', 'lbl': 'Hypoplasia of the capital femoral epiphysis', 'desc': 'label: Hypoplasia of the capital femoral epiphysis\ndefinition : Underdevelopment of the proximal epiphysis of the femur.\nsynonyms :Small capital femoral epiphyses; Small femoral capital epiphyses; Small innermost thighbone end part; Small proximal femoral epiphyses; Underdevelopment of the innermost thighbone end part\n'}


{'id': 'HP_0003091', 'url': 'http://purl.obolibrary.org/obo/HP_0003091', 'lbl': 'Trophic limb changes', 'desc': 'label: Trophic limb changes\ndefinition : Trophic changes occurring in a limb.\nsynonyms :\n'}


{'id': 'HP_0003093', 'url': 'http://purl.obolibrary.org/obo/HP_0003093', 'lbl': 'Limited hip extension', 'desc': 'label: Limited hip extension\ndefinition : Limitation of the extension of the hip, i.e., decreased ability to straighten the hip joint and thereby increase the angle between torso and thigh; moving the thigh or top of the pelvis backward.\nsynonyms :Limited hip extension; Restricted hip extension\n'}


{'id': 'HP_0003095', 'url': 'http://purl.obolibrary.org/obo/HP_0003095', 'lbl': 'Septic arthritis', 'desc': 'label: Septic arthritis\ndefinition : \nsynonyms :Infected joint\n'}


{'id': 'HP_0003097', 'url': 'http://purl.obolibrary.org/obo/HP_0003097', 'lbl': 'Short femur', 'desc': 'label: Short femur\ndefinition : An abnormal shortening of the femur.\nsynonyms :Femoral hypoplasia; Hypoplasia of the femora; Short femurs; Short thighbone\n'}


{'id': 'HP_0003099', 'url': 'http://purl.obolibrary.org/obo/HP_0003099', 'lbl': 'Fibular overgrowth', 'desc': 'label: Fibular overgrowth\ndefinition : Relatively increased growth of the fibula compared to that of the tibia.\nsynonyms :Overgrowth of calf bone\n'}


{'id': 'HP_0003100', 'url': 'http://purl.obolibrary.org/obo/HP_0003100', 'lbl': 'Slender long bone', 'desc': 'label: Slender long bone\ndefinition : Reduced diameter of a long bone.\nsynonyms :Gracile long bones; Long bones slender; Slender long bone; Slender, gracile long tubular bones; Thin long bones; Thin, gracile long bones; Slender long bones; Thin gracile long bones\n'}


{'id': 'HP_0003102', 'url': 'http://purl.obolibrary.org/obo/HP_0003102', 'lbl': 'Increased carrying angle', 'desc': 'label: Increased carrying angle\ndefinition : An abnormal increase in the carrying angle, which is the angle he long axis of the extended forearm as it lies lateral to the long axis of the arm.\nsynonyms :\n'}


{'id': 'HP_0003103', 'url': 'http://purl.obolibrary.org/obo/HP_0003103', 'lbl': 'Abnormal cortical bone morphology', 'desc': 'label: Abnormal cortical bone morphology\ndefinition : An abnormality of compact bone (also known as cortical bone), which forms the dense surface of bones.\nsynonyms :Abnormal compact bone morphology; Abnormality of cortical bone\n'}


{'id': 'HP_0003105', 'url': 'http://purl.obolibrary.org/obo/HP_0003105', 'lbl': 'Protuberances at ends of long bones', 'desc': 'label: Protuberances at ends of long bones\ndefinition : The presence of multiple protuberances (bulges, or knobs) at the ends of the long bones.\nsynonyms :Protuberances at ends of long bones\n'}


{'id': 'HP_0003106', 'url': 'http://purl.obolibrary.org/obo/HP_0003106', 'lbl': 'Subperiosteal bone resorption', 'desc': 'label: Subperiosteal bone resorption\ndefinition : Loss of bone mass occurring beneath the periosteum (the periosteum is the connective-tissue membrane that surrounds all bones except at the articular surfaces). This process may create a serrated and lace-like appearance in periosteal cortical bone.\nsynonyms :Subperiosteal erosions\n'}


{'id': 'HP_0003107', 'url': 'http://purl.obolibrary.org/obo/HP_0003107', 'lbl': 'Abnormal circulating cholesterol concentration', 'desc': 'label: Abnormal circulating cholesterol concentration\ndefinition : Any deviation from the normal concentration of cholesterol in the blood circulation.\nsynonyms :Abnormal cholesterol homeostasis; Abnormality of cholesterol metabolism\n'}


{'id': 'HP_0003108', 'url': 'http://purl.obolibrary.org/obo/HP_0003108', 'lbl': 'Hyperglycinuria', 'desc': 'label: Hyperglycinuria\ndefinition : An increased concentration of glycine in the urine.\nsynonyms :Glycinuria; High urine glycine levels\n'}


{'id': 'HP_0003109', 'url': 'http://purl.obolibrary.org/obo/HP_0003109', 'lbl': 'Hyperphosphaturia', 'desc': 'label: Hyperphosphaturia\ndefinition : An increased excretion of phosphates in the urine.\nsynonyms :High urine phosphate levels; Phosphaturia\n'}


{'id': 'HP_0003110', 'url': 'http://purl.obolibrary.org/obo/HP_0003110', 'lbl': 'Abnormality of urine homeostasis', 'desc': 'label: Abnormality of urine homeostasis\ndefinition : An abnormality of the composition of urine or the levels of its components.\nsynonyms :Pee issues; Urine issues\n'}


{'id': 'HP_0003111', 'url': 'http://purl.obolibrary.org/obo/HP_0003111', 'lbl': 'Abnormal blood ion concentration', 'desc': 'label: Abnormal blood ion concentration\ndefinition : Abnormality of the homeostasis (concentration) of a monoatomic ion.\nsynonyms :Abnormality of ion homeostasis; Electrolyte disorders; Electrolyte disturbance\n'}


{'id': 'HP_0003112', 'url': 'http://purl.obolibrary.org/obo/HP_0003112', 'lbl': 'Abnormal circulating amino acid concentration', 'desc': 'label: Abnormal circulating amino acid concentration\ndefinition : The presence of an abnormal decrease or increase of one or more amino acids in the blood circulation.\nsynonyms :Abnormality of serum amino acid level; Abnormality of serum amino acid levels\n'}


{'id': 'HP_0003113', 'url': 'http://purl.obolibrary.org/obo/HP_0003113', 'lbl': 'Hypochloremia', 'desc': 'label: Hypochloremia\ndefinition : An abnormally decreased chloride concentration in the blood.\nsynonyms :Low blood chloride levels\n'}


{'id': 'HP_0003114', 'url': 'http://purl.obolibrary.org/obo/HP_0003114', 'lbl': 'obsolete Abnormal cardiological findings', 'desc': 'label: obsolete Abnormal cardiological findings\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003115', 'url': 'http://purl.obolibrary.org/obo/HP_0003115', 'lbl': 'Abnormal EKG', 'desc': 'label: Abnormal EKG\ndefinition : Abnormal rhythm of the heart.\nsynonyms :Abnormal ECG; Abnormal EKG; Abnormal electrocardiogram; EKG abnormality\n'}


{'id': 'HP_0003116', 'url': 'http://purl.obolibrary.org/obo/HP_0003116', 'lbl': 'Abnormal echocardiogram', 'desc': 'label: Abnormal echocardiogram\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0003117', 'url': 'http://purl.obolibrary.org/obo/HP_0003117', 'lbl': 'Abnormal circulating hormone concentration', 'desc': 'label: Abnormal circulating hormone concentration\ndefinition : An abnormal concentration of a hormone in the blood.\nsynonyms :Abnormal circulating hormone level; Abnormality of circulating hormone level\n'}


{'id': 'HP_0003118', 'url': 'http://purl.obolibrary.org/obo/HP_0003118', 'lbl': 'Increased circulating cortisol level', 'desc': 'label: Increased circulating cortisol level\ndefinition : Overproduction of the hormone of cortisol by the adrenal cortex, resulting in a characteristic combination of clinical symptoms termed Cushing syndrome, with truncal obesity, a round, full face, striae atrophicae and acne, muscle weakness, and other features.\nsynonyms :Cushing syndrome; Hypercortisolism; Increased circulating cortisol level; Increased cortisol production\n'}


{'id': 'HP_0003119', 'url': 'http://purl.obolibrary.org/obo/HP_0003119', 'lbl': 'Abnormal circulating lipid concentration', 'desc': 'label: Abnormal circulating lipid concentration\ndefinition : Any deviation from the normal concentration of a lipid in the blood circulation.\nsynonyms :Dyslipidaemia; Dyslipidemia\n'}


{'id': 'HP_0003121', 'url': 'http://purl.obolibrary.org/obo/HP_0003121', 'lbl': 'Limb joint contracture', 'desc': 'label: Limb joint contracture\ndefinition : A contracture (chronic loss of joint motion due to structural changes in muscle, tendons, ligaments, or skin) that prevent normal movement of one or more joints of the limbs.\nsynonyms :Limb contractures\n'}