{'id': 'HP_0040008', 'url': 'http://purl.obolibrary.org/obo/HP_0040008', 'lbl': 'Aplasia of facial bones', 'desc': 'label: Aplasia of facial bones\ndefinition : \nsynonyms :Failure of development of facial skeleton; Absence of facial bones; Agenesis of facial bones; Aplasia of facial skeleton; Failure of development of facial bones; Missing facial bones\n'}


{'id': 'HP_0040009', 'url': 'http://purl.obolibrary.org/obo/HP_0040009', 'lbl': 'Hyperparakeratosis', 'desc': 'label: Hyperparakeratosis\ndefinition : Abnormal keratinization of the epidermal stratum coreum (horny layer) with increased keratin formation, preservation of the nuclei in the superficial cells, and absence of the stratum granulosum.\nsynonyms :\n'}


{'id': 'HP_0040010', 'url': 'http://purl.obolibrary.org/obo/HP_0040010', 'lbl': 'Small posterior fossa', 'desc': 'label: Small posterior fossa\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040011', 'url': 'http://purl.obolibrary.org/obo/HP_0040011', 'lbl': 'Flat posterior fossa', 'desc': 'label: Flat posterior fossa\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040012', 'url': 'http://purl.obolibrary.org/obo/HP_0040012', 'lbl': 'Chromosome breakage', 'desc': 'label: Chromosome breakage\ndefinition : Elevated rate of chromosomal breakage or interchanges occurring either spontaneously or following exposure to various DNA-damaging agents. This feature may be assayed by treatment of cultured lymphocytes with agents such as chemical mutagens, irradiation, and alkylating agents.\nsynonyms :High frequency of chromosome breaks in lymphocytes; Increased chromosomal breakage; Increased chromosomal breakage rate; Multiple chromosomal breaks; Tendency to chromosomal breakage\n'}


{'id': 'HP_0040013', 'url': 'http://purl.obolibrary.org/obo/HP_0040013', 'lbl': 'Decreased mitochondrial number', 'desc': 'label: Decreased mitochondrial number\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040014', 'url': 'http://purl.obolibrary.org/obo/HP_0040014', 'lbl': 'Increased mitochondrial number', 'desc': 'label: Increased mitochondrial number\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040015', 'url': 'http://purl.obolibrary.org/obo/HP_0040015', 'lbl': 'Increased activity of mitochondrial respiratory chain', 'desc': 'label: Increased activity of mitochondrial respiratory chain\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040016', 'url': 'http://purl.obolibrary.org/obo/HP_0040016', 'lbl': 'Prominent coccyx', 'desc': 'label: Prominent coccyx\ndefinition : \nsynonyms :Prominent tailbone\n'}


{'id': 'HP_0040017', 'url': 'http://purl.obolibrary.org/obo/HP_0040017', 'lbl': 'Protruding coccyx', 'desc': 'label: Protruding coccyx\ndefinition : \nsynonyms :Protruding tailbone\n'}


{'id': 'HP_0040018', 'url': 'http://purl.obolibrary.org/obo/HP_0040018', 'lbl': 'Clinodactyly of hallux', 'desc': 'label: Clinodactyly of hallux\ndefinition : \nsynonyms :Curvature of big toe\n'}


{'id': 'HP_0040019', 'url': 'http://purl.obolibrary.org/obo/HP_0040019', 'lbl': 'Finger clinodactyly', 'desc': 'label: Finger clinodactyly\ndefinition : \nsynonyms :Curvature of finger\n'}


{'id': 'HP_0040020', 'url': 'http://purl.obolibrary.org/obo/HP_0040020', 'lbl': 'Radial deviation of the 5th finger', 'desc': 'label: Radial deviation of the 5th finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040021', 'url': 'http://purl.obolibrary.org/obo/HP_0040021', 'lbl': 'obsolete Radial deviation of the thumb', 'desc': 'label: obsolete Radial deviation of the thumb\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040022', 'url': 'http://purl.obolibrary.org/obo/HP_0040022', 'lbl': 'Clinodactyly of the 2nd finger', 'desc': 'label: Clinodactyly of the 2nd finger\ndefinition : \nsynonyms :Curvature of index finger; Second finger clinodactyly\n'}


{'id': 'HP_0040023', 'url': 'http://purl.obolibrary.org/obo/HP_0040023', 'lbl': 'Clinodactyly of the thumb', 'desc': 'label: Clinodactyly of the thumb\ndefinition : \nsynonyms :Curvature of thumb\n'}


{'id': 'HP_0040024', 'url': 'http://purl.obolibrary.org/obo/HP_0040024', 'lbl': 'Clinodactyly of the 3rd finger', 'desc': 'label: Clinodactyly of the 3rd finger\ndefinition : \nsynonyms :Curvature of middle finger\n'}


{'id': 'HP_0040025', 'url': 'http://purl.obolibrary.org/obo/HP_0040025', 'lbl': 'Clinodactyly of the 4th finger', 'desc': 'label: Clinodactyly of the 4th finger\ndefinition : \nsynonyms :Curvature of ring finger\n'}


{'id': 'HP_0040030', 'url': 'http://purl.obolibrary.org/obo/HP_0040030', 'lbl': 'Chorioretinal hypopigmentation', 'desc': 'label: Chorioretinal hypopigmentation\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040031', 'url': 'http://purl.obolibrary.org/obo/HP_0040031', 'lbl': 'Chorioretinal hyperpigmentation', 'desc': 'label: Chorioretinal hyperpigmentation\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040032', 'url': 'http://purl.obolibrary.org/obo/HP_0040032', 'lbl': 'Hypoplasia of the upper eyelids', 'desc': 'label: Hypoplasia of the upper eyelids\ndefinition : \nsynonyms :Small upper eyelid; Decreased size of upper eyelid; Underdevelopment of upper eyelid; Short upper eyelid; Hypotrophic upper eyelid\n'}


{'id': 'HP_0040033', 'url': 'http://purl.obolibrary.org/obo/HP_0040033', 'lbl': 'Aplasia/Hypoplasia of the fifth metatarsal bone', 'desc': 'label: Aplasia/Hypoplasia of the fifth metatarsal bone\ndefinition : \nsynonyms :Absent/small 5th long bone of foot; Absent/underdeveloped 5th long bone of foot\n'}


{'id': 'HP_0040034', 'url': 'http://purl.obolibrary.org/obo/HP_0040034', 'lbl': 'Abnormality of the second metatarsal bone', 'desc': 'label: Abnormality of the second metatarsal bone\ndefinition : \nsynonyms :Abnormality of the 2nd long bone of foot\n'}


{'id': 'HP_0040035', 'url': 'http://purl.obolibrary.org/obo/HP_0040035', 'lbl': 'Abnormality of the fourth metatarsal bone', 'desc': 'label: Abnormality of the fourth metatarsal bone\ndefinition : \nsynonyms :Abnormality of the 4th long bone of foot\n'}


{'id': 'HP_0040036', 'url': 'http://purl.obolibrary.org/obo/HP_0040036', 'lbl': 'Onychogryposis of fingernail', 'desc': 'label: Onychogryposis of fingernail\ndefinition : Thickened fingernails.\nsynonyms :Overgrowth and curving of fingernail\n'}


{'id': 'HP_0040037', 'url': 'http://purl.obolibrary.org/obo/HP_0040037', 'lbl': 'obsolete Thin fingernail (obsolete)', 'desc': 'label: obsolete Thin fingernail (obsolete)\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040038', 'url': 'http://purl.obolibrary.org/obo/HP_0040038', 'lbl': 'obsolete Thin toenail', 'desc': 'label: obsolete Thin toenail\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040039', 'url': 'http://purl.obolibrary.org/obo/HP_0040039', 'lbl': 'Onycholysis of fingernails', 'desc': 'label: Onycholysis of fingernails\ndefinition : \nsynonyms :Detachment of fingernails; Onycholysis of fingernail\n'}


{'id': 'HP_0040040', 'url': 'http://purl.obolibrary.org/obo/HP_0040040', 'lbl': 'Toenail onycholysis', 'desc': 'label: Toenail onycholysis\ndefinition : Painless and spontaneous separation of a toenail from the nail bed.\nsynonyms :Detachment of toenails; Onycholysis of toenails\n'}


{'id': 'HP_0040042', 'url': 'http://purl.obolibrary.org/obo/HP_0040042', 'lbl': 'Aplasia of the eccrine sweat glands', 'desc': 'label: Aplasia of the eccrine sweat glands\ndefinition : \nsynonyms :Absent eccrine sweat glands\n'}


{'id': 'HP_0040043', 'url': 'http://purl.obolibrary.org/obo/HP_0040043', 'lbl': 'Hypoplasia of the eccrine sweat glands', 'desc': 'label: Hypoplasia of the eccrine sweat glands\ndefinition : \nsynonyms :Underdeveloped major sweat glands\n'}


{'id': 'HP_0040044', 'url': 'http://purl.obolibrary.org/obo/HP_0040044', 'lbl': 'Hypoplasia of the diaphragm', 'desc': 'label: Hypoplasia of the diaphragm\ndefinition : \nsynonyms :Underdeveloped diaphragm\n'}


{'id': 'HP_0040045', 'url': 'http://purl.obolibrary.org/obo/HP_0040045', 'lbl': 'Abnormal hemidiaphragm morphology', 'desc': 'label: Abnormal hemidiaphragm morphology\ndefinition : \nsynonyms :Abnormality of the hemidiaphragms\n'}


{'id': 'HP_0040046', 'url': 'http://purl.obolibrary.org/obo/HP_0040046', 'lbl': 'Abnormal left hemidiaphragm morphology', 'desc': 'label: Abnormal left hemidiaphragm morphology\ndefinition : \nsynonyms :Abnormality of the left hemidiaphragm\n'}


{'id': 'HP_0040047', 'url': 'http://purl.obolibrary.org/obo/HP_0040047', 'lbl': 'Abnormal right hemidiaphragm morphology', 'desc': 'label: Abnormal right hemidiaphragm morphology\ndefinition : \nsynonyms :Abnormality of the right hemidiaphragm\n'}


{'id': 'HP_0040048', 'url': 'http://purl.obolibrary.org/obo/HP_0040048', 'lbl': 'obsolete Aplasia of the left hemidiaphragm', 'desc': 'label: obsolete Aplasia of the left hemidiaphragm\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040049', 'url': 'http://purl.obolibrary.org/obo/HP_0040049', 'lbl': 'Macular edema', 'desc': 'label: Macular edema\ndefinition : Thickening of the retina that takes place due to accumulation of fluid in the macula as a nonspecific response to blood-retinal barrier breakdown. Macular edema is a common pathological response to a wide variety of ocular insults, most commonly after intraocular (e.g. cataract) surgery or in association with retinal vascular (e.g. diabetic eye disease, retinal vein occlusion) or inflammatory (e.g. uveitis) disease.\nsynonyms :Macular oedema\n'}


{'id': 'HP_0040050', 'url': 'http://purl.obolibrary.org/obo/HP_0040050', 'lbl': 'Sparse upper eyelashes', 'desc': 'label: Sparse upper eyelashes\ndefinition : \nsynonyms :Hypotrichosis of upper eyelashes; Partial absence of upper eyelashes; Sparse upper eyelashes\n'}


{'id': 'HP_0040051', 'url': 'http://purl.obolibrary.org/obo/HP_0040051', 'lbl': 'Abnormality of upper eyelashes', 'desc': 'label: Abnormality of upper eyelashes\ndefinition : \nsynonyms :Abnormality of upper eyelashes\n'}


{'id': 'HP_0040052', 'url': 'http://purl.obolibrary.org/obo/HP_0040052', 'lbl': 'Abnormality of lower eyelashes', 'desc': 'label: Abnormality of lower eyelashes\ndefinition : \nsynonyms :Abnormality of lower eyelashes\n'}


{'id': 'HP_0040053', 'url': 'http://purl.obolibrary.org/obo/HP_0040053', 'lbl': 'Long lower eyelashes', 'desc': 'label: Long lower eyelashes\ndefinition : \nsynonyms :Ciliary trichomegaly of lower eyelashes; Increased length of lower eyelashes; Long lower eyelashes\n'}


{'id': 'HP_0040054', 'url': 'http://purl.obolibrary.org/obo/HP_0040054', 'lbl': 'Short upper eyelashes', 'desc': 'label: Short upper eyelashes\ndefinition : \nsynonyms :Decreased length of upper eyelashes; Short upper eyelashes\n'}


{'id': 'HP_0040055', 'url': 'http://purl.obolibrary.org/obo/HP_0040055', 'lbl': 'Short lower eyelashes', 'desc': 'label: Short lower eyelashes\ndefinition : \nsynonyms :Decreased length of lower eyelashes; Short lower eyelashes\n'}


{'id': 'HP_0040056', 'url': 'http://purl.obolibrary.org/obo/HP_0040056', 'lbl': 'Absent upper eyelashes', 'desc': 'label: Absent upper eyelashes\ndefinition : \nsynonyms :Absent upper eyelashes; Atrichia of upper eyelashes; Failure of development of upper eyelashes; Agenesis of upper eyelashes; Aplasia of upper eyelashes\n'}


{'id': 'HP_0040057', 'url': 'http://purl.obolibrary.org/obo/HP_0040057', 'lbl': 'Abnormality of nasal hair', 'desc': 'label: Abnormality of nasal hair\ndefinition : \nsynonyms :Abnormality of nasal hair; Abnormality of nose hair\n'}


{'id': 'HP_0040059', 'url': 'http://purl.obolibrary.org/obo/HP_0040059', 'lbl': 'Calcification of ribs', 'desc': 'label: Calcification of ribs\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040061', 'url': 'http://purl.obolibrary.org/obo/HP_0040061', 'lbl': 'Osteosclerosis of the radius', 'desc': 'label: Osteosclerosis of the radius\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040062', 'url': 'http://purl.obolibrary.org/obo/HP_0040062', 'lbl': 'Slender radius', 'desc': 'label: Slender radius\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040063', 'url': 'http://purl.obolibrary.org/obo/HP_0040063', 'lbl': 'Decreased adipose tissue', 'desc': 'label: Decreased adipose tissue\ndefinition : \nsynonyms :Decreased fat tissue\n'}


{'id': 'HP_0040064', 'url': 'http://purl.obolibrary.org/obo/HP_0040064', 'lbl': 'Abnormality of limbs', 'desc': 'label: Abnormality of limbs\ndefinition : \nsynonyms :Abnormal limbs; Abnormality of limbs; Limb anomaly; Dysmelia\n'}


{'id': 'HP_0040065', 'url': 'http://purl.obolibrary.org/obo/HP_0040065', 'lbl': 'obsolete Abnormal morphology of bones of the upper limbs', 'desc': 'label: obsolete Abnormal morphology of bones of the upper limbs\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040066', 'url': 'http://purl.obolibrary.org/obo/HP_0040066', 'lbl': 'obsolete Abnormal morphology of bones of the lower limbs', 'desc': 'label: obsolete Abnormal morphology of bones of the lower limbs\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040068', 'url': 'http://purl.obolibrary.org/obo/HP_0040068', 'lbl': 'Abnormality of limb bone', 'desc': 'label: Abnormality of limb bone\ndefinition : \nsynonyms :Abnormality of limb bone\n'}


{'id': 'HP_0040069', 'url': 'http://purl.obolibrary.org/obo/HP_0040069', 'lbl': 'Abnormal lower limb bone morphology', 'desc': 'label: Abnormal lower limb bone morphology\ndefinition : \nsynonyms :Abnormal morphology of bones of the lower limbs; Abnormal shape of bones of the lower limbs; Abnormality of lower limb bone\n'}


{'id': 'HP_0040070', 'url': 'http://purl.obolibrary.org/obo/HP_0040070', 'lbl': 'Abnormal upper limb bone morphology', 'desc': 'label: Abnormal upper limb bone morphology\ndefinition : \nsynonyms :Abnormal morphology of bones of the upper limbs; Abnormal shape of bones of the upper limbs; Abnormality of upper limb bone\n'}


{'id': 'HP_0040071', 'url': 'http://purl.obolibrary.org/obo/HP_0040071', 'lbl': 'Abnormal morphology of ulna', 'desc': 'label: Abnormal morphology of ulna\ndefinition : Any structural anomaly of the ulna, a bone of the forearm the extends from the elbow to the little finger.\nsynonyms :\n'}


{'id': 'HP_0040072', 'url': 'http://purl.obolibrary.org/obo/HP_0040072', 'lbl': 'Abnormal forearm bone morphology', 'desc': 'label: Abnormal forearm bone morphology\ndefinition : \nsynonyms :Abnormality of forearm bone\n'}


{'id': 'HP_0040073', 'url': 'http://purl.obolibrary.org/obo/HP_0040073', 'lbl': 'Obsolete Abnormal forearm bone morphology', 'desc': 'label: Obsolete Abnormal forearm bone morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040075', 'url': 'http://purl.obolibrary.org/obo/HP_0040075', 'lbl': 'Hypopituitarism', 'desc': 'label: Hypopituitarism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040077', 'url': 'http://purl.obolibrary.org/obo/HP_0040077', 'lbl': 'obsolete Abnormal concentration of calcium in blood', 'desc': 'label: obsolete Abnormal concentration of calcium in blood\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040078', 'url': 'http://purl.obolibrary.org/obo/HP_0040078', 'lbl': 'Axonal degeneration', 'desc': 'label: Axonal degeneration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040079', 'url': 'http://purl.obolibrary.org/obo/HP_0040079', 'lbl': 'Irregular dentition', 'desc': 'label: Irregular dentition\ndefinition : \nsynonyms :Irregular teeth\n'}


{'id': 'HP_0040080', 'url': 'http://purl.obolibrary.org/obo/HP_0040080', 'lbl': 'Anteverted ears', 'desc': 'label: Anteverted ears\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040081', 'url': 'http://purl.obolibrary.org/obo/HP_0040081', 'lbl': 'Abnormal circulating creatine kinase concentration', 'desc': 'label: Abnormal circulating creatine kinase concentration\ndefinition : Any deviation from the normal circulating creatine kinase concentration.\nsynonyms :Abnormal circulating CK concentration; Abnormal circulating CPK concentration; Abnormal circulation phospho-CK concentration; Abnormal levels of creatine kinase in blood\n'}


{'id': 'HP_0040082', 'url': 'http://purl.obolibrary.org/obo/HP_0040082', 'lbl': 'Happy demeanor', 'desc': 'label: Happy demeanor\ndefinition : A conspicuously happy disposition with frequent smiling and laughing that may be context-inappropriate or unrelated to context.\nsynonyms :Happy demeanor; Happy demeanour\n'}


{'id': 'HP_0040083', 'url': 'http://purl.obolibrary.org/obo/HP_0040083', 'lbl': 'obsolete Toe walking', 'desc': 'label: obsolete Toe walking\ndefinition : Toe walking is a pattern of walking in which a person walks on balls of his or her feet, with no contact between the heels and ground. Toe-walking is common in children who are learning to walk, but most children outgrow it around the age of two years. This term refers to the persistance of toe-walking beyond the usual age.\nsynonyms :\n'}


{'id': 'HP_0040084', 'url': 'http://purl.obolibrary.org/obo/HP_0040084', 'lbl': 'Abnormal circulating renin', 'desc': 'label: Abnormal circulating renin\ndefinition : A deviation from the normal concentration of renin in the blood, a central hormone in the control of blood pressure and various other physiological functions.\nsynonyms :Abnormal circulating renin; Abnormal plasma renin\n'}


{'id': 'HP_0040085', 'url': 'http://purl.obolibrary.org/obo/HP_0040085', 'lbl': 'Abnormal circulating aldosterone', 'desc': 'label: Abnormal circulating aldosterone\ndefinition : \nsynonyms :Abnormal circulating aldosterone; Abnormal plasma aldosterone\n'}


{'id': 'HP_0040086', 'url': 'http://purl.obolibrary.org/obo/HP_0040086', 'lbl': 'Abnormal prolactin level', 'desc': 'label: Abnormal prolactin level\ndefinition : \nsynonyms :Abnormal prolactin level\n'}


{'id': 'HP_0040087', 'url': 'http://purl.obolibrary.org/obo/HP_0040087', 'lbl': 'Abnormal blood folate concentration', 'desc': 'label: Abnormal blood folate concentration\ndefinition : Any deviation from the normal concentration of folate in the blood circulation.\nsynonyms :Abnormal serum folate; Abnormality of folate in blood\n'}


{'id': 'HP_0040088', 'url': 'http://purl.obolibrary.org/obo/HP_0040088', 'lbl': 'Abnormal lymphocyte count', 'desc': 'label: Abnormal lymphocyte count\ndefinition : Any abnormality in the total number of lymphocytes in the blood.\nsynonyms :Abnormal lymphocyte count; Abnormal lymphocyte counts; Abnormal number of lymphocytes; Abnormal numbers of lymphocytes; Abnormality of lymphocyte number\n'}


{'id': 'HP_0040089', 'url': 'http://purl.obolibrary.org/obo/HP_0040089', 'lbl': 'Abnormal natural killer cell count', 'desc': 'label: Abnormal natural killer cell count\ndefinition : Any deviation from the normal overall count of natural killer (NK) cells in the circulation or a deviation from the normal distribution of NK cell subtypes.\nsynonyms :Abnormal NK cell count; Abnormal number of natural killer cells; Abnormality of natural killer cell count\n'}


{'id': 'HP_0040090', 'url': 'http://purl.obolibrary.org/obo/HP_0040090', 'lbl': 'Abnormality of the tympanic membrane', 'desc': 'label: Abnormality of the tympanic membrane\ndefinition : An abnormality of the tympanic membrane\nsynonyms :Abnormality of the eardrum\n'}


{'id': 'HP_0040091', 'url': 'http://purl.obolibrary.org/obo/HP_0040091', 'lbl': 'Asymmetry of the size of ears', 'desc': 'label: Asymmetry of the size of ears\ndefinition : \nsynonyms :Asymmetry of the size of ears\n'}


{'id': 'HP_0040092', 'url': 'http://purl.obolibrary.org/obo/HP_0040092', 'lbl': 'Asymmetry of the shape of the ears', 'desc': 'label: Asymmetry of the shape of the ears\ndefinition : \nsynonyms :Asymmetry of the shape of the ears\n'}


{'id': 'HP_0040093', 'url': 'http://purl.obolibrary.org/obo/HP_0040093', 'lbl': 'Asymmetry of the position of the ears', 'desc': 'label: Asymmetry of the position of the ears\ndefinition : \nsynonyms :Uneven ears\n'}


{'id': 'HP_0040095', 'url': 'http://purl.obolibrary.org/obo/HP_0040095', 'lbl': 'Neoplasm of the outer ear', 'desc': 'label: Neoplasm of the outer ear\ndefinition : A tumor (abnormal growth of tissue) of the outer ear.\nsynonyms :Outer ear tumor; Outer ear tumour\n'}


{'id': 'HP_0040096', 'url': 'http://purl.obolibrary.org/obo/HP_0040096', 'lbl': 'Neoplasm of the inner ear', 'desc': 'label: Neoplasm of the inner ear\ndefinition : A tumor (abnormal growth of tissue) of the inner ear.\nsynonyms :Inner ear tumor; Inner ear tumour\n'}


{'id': 'HP_0040097', 'url': 'http://purl.obolibrary.org/obo/HP_0040097', 'lbl': 'Neoplasm of the ceruminal gland', 'desc': 'label: Neoplasm of the ceruminal gland\ndefinition : A tumor (abnormal growth of tissue) of the ceruminal gland.\nsynonyms :Adenoma of the ceruminous gland; Ceruminoma; Ceruminous adenoma\n'}


{'id': 'HP_0040098', 'url': 'http://purl.obolibrary.org/obo/HP_0040098', 'lbl': 'Basalioma of the outer ear', 'desc': 'label: Basalioma of the outer ear\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040099', 'url': 'http://purl.obolibrary.org/obo/HP_0040099', 'lbl': 'Abnormality of the round window', 'desc': 'label: Abnormality of the round window\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040100', 'url': 'http://purl.obolibrary.org/obo/HP_0040100', 'lbl': 'Abnormality of the vestibular window', 'desc': 'label: Abnormality of the vestibular window\ndefinition : \nsynonyms :Abnormality of the oval window\n'}


{'id': 'HP_0040101', 'url': 'http://purl.obolibrary.org/obo/HP_0040101', 'lbl': 'Cutaneous atresia of the external auditory canal', 'desc': 'label: Cutaneous atresia of the external auditory canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040102', 'url': 'http://purl.obolibrary.org/obo/HP_0040102', 'lbl': 'Osseous atresia of the external auditory canal', 'desc': 'label: Osseous atresia of the external auditory canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040103', 'url': 'http://purl.obolibrary.org/obo/HP_0040103', 'lbl': 'Cutaneous stenosis of the external auditory canal', 'desc': 'label: Cutaneous stenosis of the external auditory canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040104', 'url': 'http://purl.obolibrary.org/obo/HP_0040104', 'lbl': 'Osseous stenosis of the external auditory canal', 'desc': 'label: Osseous stenosis of the external auditory canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040106', 'url': 'http://purl.obolibrary.org/obo/HP_0040106', 'lbl': 'Morphological abnormality of the lateral semicircular canal', 'desc': 'label: Morphological abnormality of the lateral semicircular canal\ndefinition : \nsynonyms :Morphological abnormality of the horizontal semicircular canal\n'}


{'id': 'HP_0040107', 'url': 'http://purl.obolibrary.org/obo/HP_0040107', 'lbl': 'Morphological abnormality of the posterior semicircular canal', 'desc': 'label: Morphological abnormality of the posterior semicircular canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040108', 'url': 'http://purl.obolibrary.org/obo/HP_0040108', 'lbl': 'Morphological abnormality of the anterior semicircular canal', 'desc': 'label: Morphological abnormality of the anterior semicircular canal\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040109', 'url': 'http://purl.obolibrary.org/obo/HP_0040109', 'lbl': 'Morphological abnormality of the utricle', 'desc': 'label: Morphological abnormality of the utricle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040110', 'url': 'http://purl.obolibrary.org/obo/HP_0040110', 'lbl': 'Morphological abnormality of the saccule', 'desc': 'label: Morphological abnormality of the saccule\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040111', 'url': 'http://purl.obolibrary.org/obo/HP_0040111', 'lbl': 'obsolete Bilateral external ear deformity', 'desc': 'label: obsolete Bilateral external ear deformity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040112', 'url': 'http://purl.obolibrary.org/obo/HP_0040112', 'lbl': 'Abnormal number of tubercles', 'desc': 'label: Abnormal number of tubercles\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040113', 'url': 'http://purl.obolibrary.org/obo/HP_0040113', 'lbl': 'Old-aged sensorineural hearing impairment', 'desc': 'label: Old-aged sensorineural hearing impairment\ndefinition : \nsynonyms :Presbycusis\n'}


{'id': 'HP_0040114', 'url': 'http://purl.obolibrary.org/obo/HP_0040114', 'lbl': 'Absence of the reflex of the tensor tympani muscle', 'desc': 'label: Absence of the reflex of the tensor tympani muscle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040115', 'url': 'http://purl.obolibrary.org/obo/HP_0040115', 'lbl': 'Abnormal Eustachian tube morphology', 'desc': 'label: Abnormal Eustachian tube morphology\ndefinition : A structural anomaly of the Eustachian tube (ET). The ET is a biomechanical valve between the nasopharynx and the middle ear. Physiologically, it controls the passive adaptation of the middle ear air pressure to the ambient air pressure primarily via direct muscular actions of the soft palate. In the closed state it protects the middle ear. Inadequate function of the ET causes middle ear ventilation disorders.\nsynonyms :Abnormality of the Eustachian tube\n'}


{'id': 'HP_0040116', 'url': 'http://purl.obolibrary.org/obo/HP_0040116', 'lbl': 'Aplasia of the Eustachian tube', 'desc': 'label: Aplasia of the Eustachian tube\ndefinition : \nsynonyms :Absent eustachian tube\n'}


{'id': 'HP_0040117', 'url': 'http://purl.obolibrary.org/obo/HP_0040117', 'lbl': 'Atresia of the Eustachian tube', 'desc': 'label: Atresia of the Eustachian tube\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040118', 'url': 'http://purl.obolibrary.org/obo/HP_0040118', 'lbl': 'Stenosis of the Eustachian tube', 'desc': 'label: Stenosis of the Eustachian tube\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040119', 'url': 'http://purl.obolibrary.org/obo/HP_0040119', 'lbl': 'Unilateral conductive hearing impairment', 'desc': 'label: Unilateral conductive hearing impairment\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040120', 'url': 'http://purl.obolibrary.org/obo/HP_0040120', 'lbl': 'Abnormality of the reflex of the tensor tympani muscle', 'desc': 'label: Abnormality of the reflex of the tensor tympani muscle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040121', 'url': 'http://purl.obolibrary.org/obo/HP_0040121', 'lbl': 'Abnormality of the acoustic reflex', 'desc': 'label: Abnormality of the acoustic reflex\ndefinition : An abnormality in the reflexive contraction of the middle-ear muscles in response to sound stimulation.\nsynonyms :Abnormal auditory reflex; Abnormal middle-ear-muscles (MEM) reflex; Abnormality of stapedial reflex\n'}


{'id': 'HP_0040122', 'url': 'http://purl.obolibrary.org/obo/HP_0040122', 'lbl': 'Impairment of the the acoustic reflex', 'desc': 'label: Impairment of the the acoustic reflex\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040123', 'url': 'http://purl.obolibrary.org/obo/HP_0040123', 'lbl': 'Impairment of the reflex of the tensor tympani muscle', 'desc': 'label: Impairment of the reflex of the tensor tympani muscle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040124', 'url': 'http://purl.obolibrary.org/obo/HP_0040124', 'lbl': 'obsolete Patent tuba eustachii', 'desc': 'label: obsolete Patent tuba eustachii\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040126', 'url': 'http://purl.obolibrary.org/obo/HP_0040126', 'lbl': 'Abnormal vitamin B12 level', 'desc': 'label: Abnormal vitamin B12 level\ndefinition : A deviation from the normal concentration of cobalamin (vitamin B12) in the blood. Vitamin B12 is one of the eight B vitamins.\nsynonyms :Abnormal serum cobalamin level\n'}


{'id': 'HP_0040127', 'url': 'http://purl.obolibrary.org/obo/HP_0040127', 'lbl': 'Abnormal sweat homeostasis', 'desc': 'label: Abnormal sweat homeostasis\ndefinition : An abnormality of the composition of sweat or the levels of its components.\nsynonyms :\n'}


{'id': 'HP_0040128', 'url': 'http://purl.obolibrary.org/obo/HP_0040128', 'lbl': 'Abnormal sweat electrolytes', 'desc': 'label: Abnormal sweat electrolytes\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040129', 'url': 'http://purl.obolibrary.org/obo/HP_0040129', 'lbl': 'Abnormal nerve conduction velocity', 'desc': 'label: Abnormal nerve conduction velocity\ndefinition : \nsynonyms :Abnormal nerve conduction; Abnormal nerve conduction velocities; Nerve conduction abnormalities\n'}


{'id': 'HP_0040130', 'url': 'http://purl.obolibrary.org/obo/HP_0040130', 'lbl': 'Abnormal serum iron concentration', 'desc': 'label: Abnormal serum iron concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040131', 'url': 'http://purl.obolibrary.org/obo/HP_0040131', 'lbl': 'Abnormal motor nerve conduction velocity', 'desc': 'label: Abnormal motor nerve conduction velocity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040132', 'url': 'http://purl.obolibrary.org/obo/HP_0040132', 'lbl': 'Abnormal sensory nerve conduction velocity', 'desc': 'label: Abnormal sensory nerve conduction velocity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040133', 'url': 'http://purl.obolibrary.org/obo/HP_0040133', 'lbl': 'Abnormal circulating ferritin concentration', 'desc': 'label: Abnormal circulating ferritin concentration\ndefinition : A deviation from the normal circulating concentration of ferritin. Ferritin concentration can be measured in serum or plasma.\nsynonyms :Abnormal plasma ferritin; Abnormal serum ferritin\n'}


{'id': 'HP_0040134', 'url': 'http://purl.obolibrary.org/obo/HP_0040134', 'lbl': 'Abnormal hepatic iron concentration', 'desc': 'label: Abnormal hepatic iron concentration\ndefinition : \nsynonyms :Abnormal liver iron concentration; Abnormal liver iron level\n'}


{'id': 'HP_0040135', 'url': 'http://purl.obolibrary.org/obo/HP_0040135', 'lbl': 'Abnormal transferrin saturation', 'desc': 'label: Abnormal transferrin saturation\ndefinition : Any abnormality in the serum transferrin saturation, which is calculated by dividing the serum iron level by total iron-binding capacity.\nsynonyms :\n'}


{'id': 'HP_0040137', 'url': 'http://purl.obolibrary.org/obo/HP_0040137', 'lbl': 'Comedonal acne', 'desc': 'label: Comedonal acne\ndefinition : A type of acne in which open and closed comedones comprise the majority of the lesions, with substantially fewer papules and pustules.\nsynonyms :Comedogenic acne\n'}


{'id': 'HP_0040138', 'url': 'http://purl.obolibrary.org/obo/HP_0040138', 'lbl': 'Mucinous histiocytosis', 'desc': 'label: Mucinous histiocytosis\ndefinition : Multiple subcutaneous non-fragile and skin-coloured papules characterized by interstitial infiltrate of spindle and epithelioid histiocytes, and mucin. There are well circumscribed aggregates of epithelioid histiocytes and mucin in the upper and middle dermis,with the histiocytes arranged between collagen bundles and separated from the epidermis by a Grenz zone.\nsynonyms :Histiocytosis, mucinous\n'}


{'id': 'HP_0040139', 'url': 'http://purl.obolibrary.org/obo/HP_0040139', 'lbl': 'Lipogranulomatosis', 'desc': 'label: Lipogranulomatosis\ndefinition : Yellow nodules of lipoid material are deposited in the skin and mucosae. This gives rise to granulomatous reactions.\nsynonyms :\n'}


{'id': 'HP_0040140', 'url': 'http://purl.obolibrary.org/obo/HP_0040140', 'lbl': 'Degeneration of the striatum', 'desc': 'label: Degeneration of the striatum\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040141', 'url': 'http://purl.obolibrary.org/obo/HP_0040141', 'lbl': 'Tardive dyskinesia', 'desc': 'label: Tardive dyskinesia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040142', 'url': 'http://purl.obolibrary.org/obo/HP_0040142', 'lbl': 'Reduced 5-oxoprolinase level', 'desc': 'label: Reduced 5-oxoprolinase level\ndefinition : Decreased level of the reaction 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.\nsynonyms :5-oxoprolinase deficiency\n'}


{'id': 'HP_0040143', 'url': 'http://purl.obolibrary.org/obo/HP_0040143', 'lbl': 'Dystopic os odontoideum', 'desc': 'label: Dystopic os odontoideum\ndefinition : Os odontoideum is classified into two anatomic types (orthotopic and dystopic). Os odontoideum is defined as an ossicle that consists of smooth and separate caudal portions of the odontoid process. With orthotopic os odontoideum, the ossicle moves with the anterior arch of the atlas, while the dystopic type consists of an ossicle near the basion, or one that is fused with the clivus\nsynonyms :\n'}


{'id': 'HP_0040144', 'url': 'http://purl.obolibrary.org/obo/HP_0040144', 'lbl': 'L-2-hydroxyglutaric aciduria', 'desc': 'label: L-2-hydroxyglutaric aciduria\ndefinition : An increase in the level of L-2-hydroxyglutaric acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0040145', 'url': 'http://purl.obolibrary.org/obo/HP_0040145', 'lbl': 'Dicarboxylic acidemia', 'desc': 'label: Dicarboxylic acidemia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040146', 'url': 'http://purl.obolibrary.org/obo/HP_0040146', 'lbl': 'D-2-hydroxyglutaric acidemia', 'desc': 'label: D-2-hydroxyglutaric acidemia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040147', 'url': 'http://purl.obolibrary.org/obo/HP_0040147', 'lbl': 'L-2-hydroxyglutaric acidemia', 'desc': 'label: L-2-hydroxyglutaric acidemia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040148', 'url': 'http://purl.obolibrary.org/obo/HP_0040148', 'lbl': 'Cortical myoclonus', 'desc': 'label: Cortical myoclonus\ndefinition : Cortical myoclonus mainly affects the distal upper limbs and face, which reflects the largest cortical representations of these body areas. It is often focal, but may be multifocal, bilateral or generalized, as a consequence of intracortical and transcallosal spreading of abnormal activity. It typically occurs on voluntary action and may affect speech and gait. Cortical myoclonic jerks are stimulus sensitive, typically to touch, but sensitivity to visual stimuli is also described. Most patients with cortical myoclonus have both positive myoclonus and NM, occurring either independently or together as a complex of the two kinds of myoclonus. If cortical myoclonus is prolonged and lasts for hours, days or weeks, it is called epilepsia partials continua and is considered to be a rare form of focal epileptic status. Focal cortical myoclonus almost always points to an underlining lesion of the sensori-motor cortex, which produces hyperexcitability (e.g. vascular, inflammatory or neoplastic).\nsynonyms :\n'}


{'id': 'HP_0040149', 'url': 'http://purl.obolibrary.org/obo/HP_0040149', 'lbl': 'Woolly scalp hair', 'desc': 'label: Woolly scalp hair\ndefinition : The presence of woolly hair on the scalp. The term woolly hair refers to an abnormal variant of hair that is fine, with tightly coiled curls, and often hypopigmented. Optical microscopy may reveal the presence of tight spirals and a clear diameter reduction as compared with normal hair. Electron microscopy may show flat, oval hair shafts with reduced transversal diameter.\nsynonyms :Nappy scalp hair texture; Wooly scalp hair; Afro-textured scalp hair; Kinky scalp hair texture\n'}


{'id': 'HP_0040150', 'url': 'http://purl.obolibrary.org/obo/HP_0040150', 'lbl': 'Epiblepharon of upper lid', 'desc': 'label: Epiblepharon of upper lid\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040151', 'url': 'http://purl.obolibrary.org/obo/HP_0040151', 'lbl': 'Epiblepharon of lower lid', 'desc': 'label: Epiblepharon of lower lid\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040154', 'url': 'http://purl.obolibrary.org/obo/HP_0040154', 'lbl': 'Acne inversa', 'desc': "label: Acne inversa\ndefinition : A chronic skin condition involving the inflammation of the apocrine sweat glands, forming pimple-like bumps known as abscesses.\nsynonyms :Hidradenitis suppurativa; Pyoderma fistulans significa; Smoker's boils; Verneuil's disease\n"}


{'id': 'HP_0040155', 'url': 'http://purl.obolibrary.org/obo/HP_0040155', 'lbl': 'Elevated urinary 3-hydroxybutyric acid', 'desc': 'label: Elevated urinary 3-hydroxybutyric acid\ndefinition : An increased amount of 3-hydroxybutyric acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0040156', 'url': 'http://purl.obolibrary.org/obo/HP_0040156', 'lbl': 'Elevated urinary carboxylic acid', 'desc': 'label: Elevated urinary carboxylic acid\ndefinition : An increased amount of carboxylic acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0040157', 'url': 'http://purl.obolibrary.org/obo/HP_0040157', 'lbl': 'Abnormal intermamillary distance', 'desc': 'label: Abnormal intermamillary distance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040158', 'url': 'http://purl.obolibrary.org/obo/HP_0040158', 'lbl': 'Short intermamillary distance', 'desc': 'label: Short intermamillary distance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040159', 'url': 'http://purl.obolibrary.org/obo/HP_0040159', 'lbl': 'Abnormal spaced incisors', 'desc': 'label: Abnormal spaced incisors\ndefinition : \nsynonyms :Abnormal spaced incisors; Abnormality of spacing of front teeth; Abnormality of spacing of incisors\n'}


{'id': 'HP_0040160', 'url': 'http://purl.obolibrary.org/obo/HP_0040160', 'lbl': 'Generalized osteoporosis', 'desc': 'label: Generalized osteoporosis\ndefinition : \nsynonyms :Generalised osteoporosis; Generalised osteoporosis with pathologic fractures; Generalized osteoporosis with pathologic fractures\n'}


{'id': 'HP_0040161', 'url': 'http://purl.obolibrary.org/obo/HP_0040161', 'lbl': 'Localized osteoporosis', 'desc': 'label: Localized osteoporosis\ndefinition : \nsynonyms :Localised osteoporosis\n'}


{'id': 'HP_0040162', 'url': 'http://purl.obolibrary.org/obo/HP_0040162', 'lbl': 'Orthokeratosis', 'desc': 'label: Orthokeratosis\ndefinition : Formation of an anuclear keratin layer\nsynonyms :\n'}


{'id': 'HP_0040163', 'url': 'http://purl.obolibrary.org/obo/HP_0040163', 'lbl': 'Abnormal pelvis bone morphology', 'desc': 'label: Abnormal pelvis bone morphology\ndefinition : \nsynonyms :Abnormal shape of pelvis bone\n'}


{'id': 'HP_0040164', 'url': 'http://purl.obolibrary.org/obo/HP_0040164', 'lbl': 'Lipomas of eyelids', 'desc': 'label: Lipomas of eyelids\ndefinition : Fatty tumors on the eyelids.\nsynonyms :Fatty tumors on the eyelids; Fatty tumours on the eyelids\n'}


{'id': 'HP_0040165', 'url': 'http://purl.obolibrary.org/obo/HP_0040165', 'lbl': 'Periostitis', 'desc': 'label: Periostitis\ndefinition : Inflammation of the periosteum\nsynonyms :Periostalgia\n'}


{'id': 'HP_0040166', 'url': 'http://purl.obolibrary.org/obo/HP_0040166', 'lbl': 'obsolete Abnormality of the periosteum', 'desc': 'label: obsolete Abnormality of the periosteum\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040167', 'url': 'http://purl.obolibrary.org/obo/HP_0040167', 'lbl': 'Facial papilloma', 'desc': 'label: Facial papilloma\ndefinition : \nsynonyms :Facial verruca; Facial wart\n'}


{'id': 'HP_0040168', 'url': 'http://purl.obolibrary.org/obo/HP_0040168', 'lbl': 'obsolete Focal seizures, afebril', 'desc': 'label: obsolete Focal seizures, afebril\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040169', 'url': 'http://purl.obolibrary.org/obo/HP_0040169', 'lbl': 'Loose anagen hair', 'desc': 'label: Loose anagen hair\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040170', 'url': 'http://purl.obolibrary.org/obo/HP_0040170', 'lbl': 'Abnormality of hair growth', 'desc': 'label: Abnormality of hair growth\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040171', 'url': 'http://purl.obolibrary.org/obo/HP_0040171', 'lbl': 'Decreased serum testosterone concentration', 'desc': 'label: Decreased serum testosterone concentration\ndefinition : \nsynonyms :Decreased testosterone; Decreased serum testosterone level; Decreased serum testosterone levels; Low serum testosterone level; Low serum testosterone levels\n'}


{'id': 'HP_0040172', 'url': 'http://purl.obolibrary.org/obo/HP_0040172', 'lbl': 'Abnormality of occipitofrontalis muscle', 'desc': 'label: Abnormality of occipitofrontalis muscle\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040173', 'url': 'http://purl.obolibrary.org/obo/HP_0040173', 'lbl': 'Abnormality of the tongue muscle', 'desc': 'label: Abnormality of the tongue muscle\ndefinition : \nsynonyms :Abnormality of lingual muscle; Abnormality of the tongue muscle\n'}


{'id': 'HP_0040174', 'url': 'http://purl.obolibrary.org/obo/HP_0040174', 'lbl': 'Abnormality of extrinsic muscle of tongue', 'desc': 'label: Abnormality of extrinsic muscle of tongue\ndefinition : \nsynonyms :Abnormality of extrinsic lingual muscle\n'}


{'id': 'HP_0040175', 'url': 'http://purl.obolibrary.org/obo/HP_0040175', 'lbl': 'Platelet-activating factor acetylhydrolase deficiency', 'desc': 'label: Platelet-activating factor acetylhydrolase deficiency\ndefinition : Reduced level of platelet-activating factor acetylhydrolase.\nsynonyms :\n'}


{'id': 'HP_0040176', 'url': 'http://purl.obolibrary.org/obo/HP_0040176', 'lbl': 'Abnormal circulating phospholipid concentration', 'desc': 'label: Abnormal circulating phospholipid concentration\ndefinition : Any deviation from the normal concentration of a phospholipid in the blood circulation.\nsynonyms :Abnormal level of phospholipids\n'}


{'id': 'HP_0040177', 'url': 'http://purl.obolibrary.org/obo/HP_0040177', 'lbl': 'Abnormal level of platelet-activating factor', 'desc': 'label: Abnormal level of platelet-activating factor\ndefinition : \nsynonyms :Abnormal level of PAF\n'}


{'id': 'HP_0040178', 'url': 'http://purl.obolibrary.org/obo/HP_0040178', 'lbl': 'Increased level of platelet-activating factor', 'desc': 'label: Increased level of platelet-activating factor\ndefinition : \nsynonyms :Increased level of PAF\n'}


{'id': 'HP_0040179', 'url': 'http://purl.obolibrary.org/obo/HP_0040179', 'lbl': 'Decreased level of platelet-activating factor', 'desc': 'label: Decreased level of platelet-activating factor\ndefinition : \nsynonyms :Decreased level of PAF\n'}


{'id': 'HP_0040180', 'url': 'http://purl.obolibrary.org/obo/HP_0040180', 'lbl': 'obsolete Hyperkeratosis pilaris', 'desc': 'label: obsolete Hyperkeratosis pilaris\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040181', 'url': 'http://purl.obolibrary.org/obo/HP_0040181', 'lbl': 'Chapped lip', 'desc': 'label: Chapped lip\ndefinition : Cracking, fissuring, and peeling of the skin of the lips.\nsynonyms :Chapped lip; Chapped lips; Cheilitis simplex; Common cheilitis; Dry lips; Perioral dermatitis\n'}


{'id': 'HP_0040182', 'url': 'http://purl.obolibrary.org/obo/HP_0040182', 'lbl': 'Inappropriate sinus tachycardia', 'desc': 'label: Inappropriate sinus tachycardia\ndefinition : Inappropriate sinus tachycardia is a nonparoxysmal tachyarrhythmia characterized by an increased resting heart rate (HR) and/or an exaggerated HR response to minimal exertion or a change in body posture. HR is constantly above the physiological range with no appropriate relation to metabolic or physiological demands.\nsynonyms :\n'}


{'id': 'HP_0040183', 'url': 'http://purl.obolibrary.org/obo/HP_0040183', 'lbl': 'Encopresis', 'desc': 'label: Encopresis\ndefinition : \nsynonyms :Stool holding; Stool soiling\n'}


{'id': 'HP_0040184', 'url': 'http://purl.obolibrary.org/obo/HP_0040184', 'lbl': 'Oral bleeding', 'desc': 'label: Oral bleeding\ndefinition : \nsynonyms :Oral bleeding; Oral haemorrhage; Oral hemorrhage\n'}


{'id': 'HP_0040185', 'url': 'http://purl.obolibrary.org/obo/HP_0040185', 'lbl': 'Macrothrombocytopenia', 'desc': 'label: Macrothrombocytopenia\ndefinition : \nsynonyms :Macrothrombozytopenia\n'}


{'id': 'HP_0040186', 'url': 'http://purl.obolibrary.org/obo/HP_0040186', 'lbl': 'Maculopapular exanthema', 'desc': 'label: Maculopapular exanthema\ndefinition : A skin rash that is characterized by diffuse cutaneous erythema with areas of skin elevation. It may evolve to vesicles or papules as part of a more severe clinical entity. Different degrees of angioedema with involvement of subcutaneous tissue may also appear.\nsynonyms :\n'}


{'id': 'HP_0040187', 'url': 'http://purl.obolibrary.org/obo/HP_0040187', 'lbl': 'Neonatal sepsis', 'desc': 'label: Neonatal sepsis\ndefinition : Systemic inflammatory response to infection in newborn babies.\nsynonyms :\n'}


{'id': 'HP_0040188', 'url': 'http://purl.obolibrary.org/obo/HP_0040188', 'lbl': 'Osteochondrosis', 'desc': 'label: Osteochondrosis\ndefinition : Abnormal growth ossification centers in children. Initially a degeneration/ necrosis followed by regeneration or recalcification.\nsynonyms :\n'}


{'id': 'HP_0040189', 'url': 'http://purl.obolibrary.org/obo/HP_0040189', 'lbl': 'Scaling skin', 'desc': 'label: Scaling skin\ndefinition : Refers to the loss of the outer layer of the epidermis in large, scale-like flakes.\nsynonyms :Desquamation; Scaling skin; Scaly skin; flaking skin; peeling skin\n'}


{'id': 'HP_0040190', 'url': 'http://purl.obolibrary.org/obo/HP_0040190', 'lbl': 'White scaling skin', 'desc': 'label: White scaling skin\ndefinition : \nsynonyms :White scaling skin; White scaly skin\n'}


{'id': 'HP_0040191', 'url': 'http://purl.obolibrary.org/obo/HP_0040191', 'lbl': 'Rectus femoris muscle atrophy', 'desc': 'label: Rectus femoris muscle atrophy\ndefinition : \nsynonyms :Atrophy of the rectus femoris muscles\n'}


{'id': 'HP_0040192', 'url': 'http://purl.obolibrary.org/obo/HP_0040192', 'lbl': 'APUdoma', 'desc': 'label: APUdoma\ndefinition : An endocrine tumor arising from an APUD cell.\nsynonyms :amine precursor uptake and decarboxylation tumours\n'}


{'id': 'HP_0040193', 'url': 'http://purl.obolibrary.org/obo/HP_0040193', 'lbl': 'obsolete Pinealoblastoma', 'desc': 'label: obsolete Pinealoblastoma\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040194', 'url': 'http://purl.obolibrary.org/obo/HP_0040194', 'lbl': 'Increased head circumference', 'desc': 'label: Increased head circumference\ndefinition : An abnormally increased head circumference in a growing child. Head circumference is measured with a nonelastic tape and comprises the distance from above the eyebrows and ears and around the back of the head. The measured HC is then plotted on an appropriate growth chart.\nsynonyms :Increased head circumference\n'}


{'id': 'HP_0040195', 'url': 'http://purl.obolibrary.org/obo/HP_0040195', 'lbl': 'Decreased head circumference', 'desc': 'label: Decreased head circumference\ndefinition : An abnormally reduced head circumference in a growing child. Head circumference is measured with a nonelastic tape and comprises the distance from above the eyebrows and ears and around the back of the head. The measured HC is then plotted on an appropriate growth chart. Microcephaly is defined as a head circumference (HC) that is great than two standard deviations below the mean of age- and gender-matched population based samples. Severe microcephaly is defined with an HC that is three standard deviations below the mean.\nsynonyms :Decreased head circumference\n'}


{'id': 'HP_0040196', 'url': 'http://purl.obolibrary.org/obo/HP_0040196', 'lbl': 'Mild microcephaly', 'desc': 'label: Mild microcephaly\ndefinition : Decreased occipito-frontal (head) circumference (OFC). For the microcephaly OFC must be between -3 SD and -2 SD compared to appropriate, age matched, normal standards (i.e. -3 SD <= OFC < -2 SD).\nsynonyms :\n'}


{'id': 'HP_0040197', 'url': 'http://purl.obolibrary.org/obo/HP_0040197', 'lbl': 'Encephalomalacia', 'desc': 'label: Encephalomalacia\ndefinition : Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.\nsynonyms :Cerebral softening\n'}


{'id': 'HP_0040198', 'url': 'http://purl.obolibrary.org/obo/HP_0040198', 'lbl': 'Non-medullary thyroid carcinoma', 'desc': 'label: Non-medullary thyroid carcinoma\ndefinition : \nsynonyms :Nonmedullary thyroid carcinoma; Thyroid cancer, nonmedullary\n'}


{'id': 'HP_0040199', 'url': 'http://purl.obolibrary.org/obo/HP_0040199', 'lbl': 'obsolete Flat midface', 'desc': 'label: obsolete Flat midface\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040200', 'url': 'http://purl.obolibrary.org/obo/HP_0040200', 'lbl': 'Motor impersistence', 'desc': "label: Motor impersistence\ndefinition : The inability to maintain postures or positions (such as keeping eyes closed, protruding the tongue, maintaining conjugate gaze steadily in a fixed direction, or making a prolonged 'ah' sound) without repeated prompts.\nsynonyms :Negative chorea\n"}


{'id': 'HP_0040201', 'url': 'http://purl.obolibrary.org/obo/HP_0040201', 'lbl': 'Simultanapraxia', 'desc': 'label: Simultanapraxia\ndefinition : A subset of motor impersistence, defined as the inability to perform more than two of the simple voluntary acts simultaneously, such as closing the eyes and protruding the tongue.\nsynonyms :\n'}


{'id': 'HP_0040202', 'url': 'http://purl.obolibrary.org/obo/HP_0040202', 'lbl': 'Abnormal consumption behavior', 'desc': 'label: Abnormal consumption behavior\ndefinition : Abnormal and compulsive consumption of food, liquid, or objects that could have negative consequences for the individual\nsynonyms :Abnormal consumption behaviour\n'}


{'id': 'HP_0040203', 'url': 'http://purl.obolibrary.org/obo/HP_0040203', 'lbl': 'Abnormal CSF neopterin concentration', 'desc': 'label: Abnormal CSF neopterin concentration\ndefinition : Abnormal concentration of neopterin in the cerebrospinal fluid (CSF).\nsynonyms :Abnormal CSF neopterin level\n'}


{'id': 'HP_0040204', 'url': 'http://purl.obolibrary.org/obo/HP_0040204', 'lbl': 'Elevated CSF neopterin level', 'desc': 'label: Elevated CSF neopterin level\ndefinition : Increased concentration of neopterin in the cerebrospinal fluid (CSF).\nsynonyms :\n'}


{'id': 'HP_0040205', 'url': 'http://purl.obolibrary.org/obo/HP_0040205', 'lbl': 'Decreased CSF neopterin level', 'desc': 'label: Decreased CSF neopterin level\ndefinition : Decreased concentration of neopterin in the cerebrospinal fluid (CSF).\nsynonyms :\n'}


{'id': 'HP_0040206', 'url': 'http://purl.obolibrary.org/obo/HP_0040206', 'lbl': 'Abnormal circulating neopterin concentration', 'desc': 'label: Abnormal circulating neopterin concentration\ndefinition : Any deviation from the normal concentration of neopterin in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0040207', 'url': 'http://purl.obolibrary.org/obo/HP_0040207', 'lbl': 'Abnormal CSF biopterin concentration', 'desc': 'label: Abnormal CSF biopterin concentration\ndefinition : Abnormal concentration of biopterin in the cerebrospinal fluid (CSF).\nsynonyms :Abnormal CSF biopterin level; Abnormal cerebrospinal fluid biopterin level\n'}


{'id': 'HP_0040208', 'url': 'http://purl.obolibrary.org/obo/HP_0040208', 'lbl': 'Elevated CSF biopterin level', 'desc': 'label: Elevated CSF biopterin level\ndefinition : Concentration of biopterin in the cerebrospinal fluid (CSF) above the upper limit of normal.\nsynonyms :\n'}


{'id': 'HP_0040209', 'url': 'http://purl.obolibrary.org/obo/HP_0040209', 'lbl': 'Decreased CSF biopterin level', 'desc': 'label: Decreased CSF biopterin level\ndefinition : Concentration of biopterin in the cerebrospinal fluid (CSF) below the lower limit of normal.\nsynonyms :Decreased cerebrospinal fluid biopterin level\n'}


{'id': 'HP_0040210', 'url': 'http://purl.obolibrary.org/obo/HP_0040210', 'lbl': 'Abnormal circulating biopterin concentration', 'desc': 'label: Abnormal circulating biopterin concentration\ndefinition : A deviation from the normal concentration of biopterin in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0040211', 'url': 'http://purl.obolibrary.org/obo/HP_0040211', 'lbl': 'Abnormal skin morphology of the palm', 'desc': 'label: Abnormal skin morphology of the palm\ndefinition : An abnormality of the skin of the palm, that is, the skin of the front of the hand.\nsynonyms :\n'}


{'id': 'HP_0040212', 'url': 'http://purl.obolibrary.org/obo/HP_0040212', 'lbl': 'Risus sardonicus', 'desc': 'label: Risus sardonicus\ndefinition : Fixed sarcastic grimace and anxious expression. Caused by spasms of the masseter and other facial muscles.\nsynonyms :Rictus grin\n'}


{'id': 'HP_0040213', 'url': 'http://purl.obolibrary.org/obo/HP_0040213', 'lbl': 'Hypopnea', 'desc': 'label: Hypopnea\ndefinition : Hypopnea is referring to breathing that is abnormally shallow.\nsynonyms :Shallow breathing\n'}


{'id': 'HP_0040214', 'url': 'http://purl.obolibrary.org/obo/HP_0040214', 'lbl': 'Abnormal circulating insulin concentration', 'desc': 'label: Abnormal circulating insulin concentration\ndefinition : An abnormal concentration of insulin in the body.\nsynonyms :Abnormal insulin level\n'}


{'id': 'HP_0040215', 'url': 'http://purl.obolibrary.org/obo/HP_0040215', 'lbl': 'obsolete Abnormal circulating insulin level', 'desc': 'label: obsolete Abnormal circulating insulin level\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040216', 'url': 'http://purl.obolibrary.org/obo/HP_0040216', 'lbl': 'Hypoinsulinemia', 'desc': 'label: Hypoinsulinemia\ndefinition : A decreased concentration of insulin in the blood.\nsynonyms :\n'}


{'id': 'HP_0040217', 'url': 'http://purl.obolibrary.org/obo/HP_0040217', 'lbl': 'Elevated hemoglobin A1c', 'desc': 'label: Elevated hemoglobin A1c\ndefinition : An increased concentration of hemoglobin A1c (HbA1c), which is the product of nonenzymatic attachment of a hexose molecule to the N-terminal amino acid of the hemoglobin molecule. This reaction is dependent on blood glucose concentration, and therefore reflects the mean glucose concentration over the previous 8 to 12 weeks. The HbA1c level provides a better indication of long-term glycemic control than one-time blood or urinary glucose measurements.\nsynonyms :Elevated HbA1c; Elevated glycated haemoglobin; Elevated glycated hemoglobin; Elevated glycosylated haemoglobin; Elevated glycosylated hemoglobin; Elevated haemoglobin A1c; Increased HbA1c levels\n'}


{'id': 'HP_0040218', 'url': 'http://purl.obolibrary.org/obo/HP_0040218', 'lbl': 'Reduced natural killer cell count', 'desc': 'label: Reduced natural killer cell count\ndefinition : Less than normal number of natural killer cells, a type of lymphocyte in the innate immune system with an ability to mediate cytotoxicity and produce cytokines after the ligation of a germline-encoded activation receptor.\nsynonyms :Reduced NK cell number; Reduced natural killer cell number\n'}


{'id': 'HP_0040219', 'url': 'http://purl.obolibrary.org/obo/HP_0040219', 'lbl': 'Absent natural killer cells', 'desc': 'label: Absent natural killer cells\ndefinition : Lack of natural killer cells, a type of lymphocyte in the innate immune system that contains cytoplasmic granzymes, i.e., small granules with perforin and proteases that allow natural killer cells to form pores in the cell membrane of the target cell through which the granzymes and associated molecules can enter, inducing apoptosis.\nsynonyms :Absent NK cells\n'}


{'id': 'HP_0040220', 'url': 'http://purl.obolibrary.org/obo/HP_0040220', 'lbl': 'Abnormal size of the dental root', 'desc': 'label: Abnormal size of the dental root\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040221', 'url': 'http://purl.obolibrary.org/obo/HP_0040221', 'lbl': 'Hypoplasia of the dental root', 'desc': 'label: Hypoplasia of the dental root\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040222', 'url': 'http://purl.obolibrary.org/obo/HP_0040222', 'lbl': 'Maternal thrombophilia', 'desc': 'label: Maternal thrombophilia\ndefinition : An increased tendency towards thrombosis in the mother during a pregnancy.\nsynonyms :\n'}


{'id': 'HP_0040223', 'url': 'http://purl.obolibrary.org/obo/HP_0040223', 'lbl': 'Pulmonary hemorrhage', 'desc': 'label: Pulmonary hemorrhage\ndefinition : Pulmonary hemorrhage is a bleeding within the lungs. Older children and adults may spit blood or bloody sputum. Neonates, infants and young children usually do not spit up blood. Anemia, pulmonary infiltrates, increasingling bloody return on BAL and the presence of hemosiderin-laden macrophages in broncho-alveolar lavage (BAL) fluid or lung biopsy can diagnose lung bleeding. Alveolar macrophages contain phagocytosed red blood cells and stain positive for hemosiderin, a product of hemoglobin degradation, after about 48-72 hours following pulmonary hemorraghe. Previous or recurrent bleeding can thus be distinguished from fresh events. A differentiation into local or diffuse is of importance. Also differentiate if pulmonary hemorrhage is due to a primary lung disorder or a manifestation of a systemic disease.\nsynonyms :Intrapulmonary haemorrhage; Intrapulmonary hemorrhage; Pulmonary haemorrhage\n'}


{'id': 'HP_0040224', 'url': 'http://purl.obolibrary.org/obo/HP_0040224', 'lbl': 'Abnormality of fibrinolysis', 'desc': 'label: Abnormality of fibrinolysis\ndefinition : Clincial phenotype characterized by delayed bleeding accelerated break down of blood clot (fibrinolysis)\nsynonyms :Abnormality of the fibrinolytic system\n'}


{'id': 'HP_0040225', 'url': 'http://purl.obolibrary.org/obo/HP_0040225', 'lbl': 'Decrease in high molecular weight von Willebrand factor Multimers', 'desc': 'label: Decrease in high molecular weight von Willebrand factor Multimers\ndefinition : A decrease in high molecular weight von Willebrand factor multimers.\nsynonyms :Decrease in HMW VWF multimers\n'}


{'id': 'HP_0040226', 'url': 'http://purl.obolibrary.org/obo/HP_0040226', 'lbl': 'Decreased level of heparin co-factor II', 'desc': 'label: Decreased level of heparin co-factor II\ndefinition : An abnormality of coagulation related to a decreased concentration of heparin co-factor II\nsynonyms :Heparin co-factor II deficiency\n'}


{'id': 'HP_0040227', 'url': 'http://purl.obolibrary.org/obo/HP_0040227', 'lbl': 'Decreased level of histidine-rich glycoprotein', 'desc': 'label: Decreased level of histidine-rich glycoprotein\ndefinition : Decrease of these levels result in increased inhibition of fibrinolysis and reduced inhibition of coagulation\nsynonyms :\n'}


{'id': 'HP_0040228', 'url': 'http://purl.obolibrary.org/obo/HP_0040228', 'lbl': 'Decreased level of plasminogen', 'desc': 'label: Decreased level of plasminogen\ndefinition : A decreased level of Plasminogen\nsynonyms :Hypoplasminogenemia\n'}


{'id': 'HP_0040229', 'url': 'http://purl.obolibrary.org/obo/HP_0040229', 'lbl': 'Decreased level of thrombomodulin', 'desc': 'label: Decreased level of thrombomodulin\ndefinition : Thrombomodulin is a cofactor in the thrombin induced activation of Protein C. In the case of deficiency there will be less Protein C and tendency to clot\nsynonyms :BDCA-3\n'}


{'id': 'HP_0040230', 'url': 'http://purl.obolibrary.org/obo/HP_0040230', 'lbl': 'Decreased level of tissue plasminogen activator', 'desc': 'label: Decreased level of tissue plasminogen activator\ndefinition : The tPA protein catalyzes the conversion of plasiminogen to plasmin, and thus break down of clots. When there is a deficiency there will be an increase of thrombosis\nsynonyms :Decreased level of tPA\n'}


{'id': 'HP_0040231', 'url': 'http://purl.obolibrary.org/obo/HP_0040231', 'lbl': 'Abnormal onset of bleeding', 'desc': 'label: Abnormal onset of bleeding\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040232', 'url': 'http://purl.obolibrary.org/obo/HP_0040232', 'lbl': 'Delayed onset bleeding', 'desc': 'label: Delayed onset bleeding\ndefinition : Abnormal bleeding related to a procedure or trauma which does not start at the time of the initial insult, but after delay by at least 24 hours.\nsynonyms :\n'}


{'id': 'HP_0040233', 'url': 'http://purl.obolibrary.org/obo/HP_0040233', 'lbl': 'Factor XIII subunit A deficiency', 'desc': 'label: Factor XIII subunit A deficiency\ndefinition : Deficiency of factor XIII subunit A, leading to a reduced factor XIII activity. Activated Factor XIII cross-links fibrin polymers solidifying the clot.\nsynonyms :Reduced factor XIII, subunit A\n'}


{'id': 'HP_0040234', 'url': 'http://purl.obolibrary.org/obo/HP_0040234', 'lbl': 'Factor XIII subunit B deficiency', 'desc': 'label: Factor XIII subunit B deficiency\ndefinition : Deficiency of factor XIII subunit B, leading to a reduced factor XIII activity. Activated Factor XIII cross-links fibrin polymers solidifying the clot.\nsynonyms :Reduced factor XIII, subunit B\n'}


{'id': 'HP_0040235', 'url': 'http://purl.obolibrary.org/obo/HP_0040235', 'lbl': 'Leukocyte inclusion bodies', 'desc': 'label: Leukocyte inclusion bodies\ndefinition : The presence of intraceullar inclusion bodies (aggregates of stainable substances, usually proteins) in leukocytes.\nsynonyms :Dohle-like leukocyte inclusion bodies; Inclusion bodies in leukocytes\n'}


{'id': 'HP_0040236', 'url': 'http://purl.obolibrary.org/obo/HP_0040236', 'lbl': 'Hyperfibrinolysis', 'desc': 'label: Hyperfibrinolysis\ndefinition : Increased degradation of fibrin, associated with clot instability and bleeding\nsynonyms :\n'}


{'id': 'HP_0040237', 'url': 'http://purl.obolibrary.org/obo/HP_0040237', 'lbl': 'Impaired binding of factor VIII to VWF', 'desc': 'label: Impaired binding of factor VIII to VWF\ndefinition : Impaired binding of factor VIII to von Willebrand Factor. This is determined using a modified ELISA assay.\nsynonyms :von Willebrand Disease Type II Normandy\n'}


{'id': 'HP_0040238', 'url': 'http://purl.obolibrary.org/obo/HP_0040238', 'lbl': 'Impaired neutrophil chemotaxis', 'desc': 'label: Impaired neutrophil chemotaxis\ndefinition : An impairment of the migration of neutrophils towards chemoattractants as part of the innate immune response\nsynonyms :Neutrophil migratory defect\n'}


{'id': 'HP_0040239', 'url': 'http://purl.obolibrary.org/obo/HP_0040239', 'lbl': 'Increased plasma vitamin K epoxide after vitamin K supplementation', 'desc': 'label: Increased plasma vitamin K epoxide after vitamin K supplementation\ndefinition : Increased plasma vitamin K epoxide after vitamin K supplementation is present in VKCFD (vitamin K-dependent clotting factor deficiency) type 2, but not in VKCFD type 1.\nsynonyms :\n'}


{'id': 'HP_0040240', 'url': 'http://purl.obolibrary.org/obo/HP_0040240', 'lbl': 'Increased ratio of VWF propeptide to VWF antigen', 'desc': 'label: Increased ratio of VWF propeptide to VWF antigen\ndefinition : An increased VWF propeptide to VWF antigen indicates that deficiency of VWF is not due to impaired synthesis but due to rapid clearance. The VWF propeptide is measured by ELISA.\nsynonyms :\n'}


{'id': 'HP_0040241', 'url': 'http://purl.obolibrary.org/obo/HP_0040241', 'lbl': 'Increased RIPA', 'desc': 'label: Increased RIPA\ndefinition : Increased platelet agglutination in response to low-dose ristocetin\nsynonyms :\n'}


{'id': 'HP_0040242', 'url': 'http://purl.obolibrary.org/obo/HP_0040242', 'lbl': 'Muscle hemorrhage', 'desc': 'label: Muscle hemorrhage\ndefinition : Bleeding occuring within a muscle\nsynonyms :Muscle haemorrhage\n'}


{'id': 'HP_0040243', 'url': 'http://purl.obolibrary.org/obo/HP_0040243', 'lbl': 'Prolonged euglobulin clot lysis time', 'desc': 'label: Prolonged euglobulin clot lysis time\ndefinition : Abnormally increased length of time required for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. This test is a clinical assay used to measure fibrinolysis. The euglobulin fraction of plasma is precipitated and used to form clot by addition of thrombin; after clot forms the rate of clot breakdown (fibrinolysis) can be monitored.\nsynonyms :\n'}


{'id': 'HP_0040244', 'url': 'http://purl.obolibrary.org/obo/HP_0040244', 'lbl': "Prolonged Russell's viper venom time", 'desc': "label: Prolonged Russell's viper venom time\ndefinition : Increased time to coagulation in the Russell's viper venom assay\nsynonyms :\n"}


{'id': 'HP_0040245', 'url': 'http://purl.obolibrary.org/obo/HP_0040245', 'lbl': 'Reduced alpha-2-antiplasmin activity', 'desc': 'label: Reduced alpha-2-antiplasmin activity\ndefinition : Reduced activity of alpha-2-antiplasmin. This protein inactivates the protease plasmin that drives fibrinolysis.\nsynonyms :\n'}


{'id': 'HP_0040246', 'url': 'http://purl.obolibrary.org/obo/HP_0040246', 'lbl': 'Reduced antithrombin antigen', 'desc': 'label: Reduced antithrombin antigen\ndefinition : Reduced antithrombin antigen. A reduced level of antithrombin may lead to an increased risk of thrombus formation.\nsynonyms :\n'}


{'id': 'HP_0040247', 'url': 'http://purl.obolibrary.org/obo/HP_0040247', 'lbl': 'Reduced euglobulin clot lysis time', 'desc': 'label: Reduced euglobulin clot lysis time\ndefinition : Abnormally decreased length of time required for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. This test is a clinical assay used to measure fibrinolysis. The euglobulin fraction of plasma is precipitated and used to form clot by addition of thrombin; after clot forms the rate of clot breakdown (fibrinolysis) can be monitored.\nsynonyms :\n'}


{'id': 'HP_0040248', 'url': 'http://purl.obolibrary.org/obo/HP_0040248', 'lbl': 'Reduced plasminogen activator inhibitor 1 activity', 'desc': 'label: Reduced plasminogen activator inhibitor 1 activity\ndefinition : Reduced activity of plasminogen activator inhibitor 1. This protein down-regulates fibrinolysis in the circulation by inhibiting the two major plasminogen activators: tissue-plasminogen activator and urokinase-plasminogen activator.\nsynonyms :\n'}


{'id': 'HP_0040249', 'url': 'http://purl.obolibrary.org/obo/HP_0040249', 'lbl': 'Reduced plasminogen activator inhibitor 1 antigen', 'desc': 'label: Reduced plasminogen activator inhibitor 1 antigen\ndefinition : Reduced level of plasminogen activator inhibitor 1 antigen.\nsynonyms :\n'}


{'id': 'HP_0040250', 'url': 'http://purl.obolibrary.org/obo/HP_0040250', 'lbl': 'Reduced prothrombin antigen', 'desc': 'label: Reduced prothrombin antigen\ndefinition : Reduced prothrombin antigen as measured by ELISA assay. Prothrombin is a vitamin K-dependent coagulation factor that is proteolytically cleaved to form thrombin.\nsynonyms :\n'}


{'id': 'HP_0040251', 'url': 'http://purl.obolibrary.org/obo/HP_0040251', 'lbl': 'Hand dimple', 'desc': 'label: Hand dimple\ndefinition : A cutaneous indentation resulting from tethering of the skin to underlying structures (bone) of the hand.\nsynonyms :Hand dimples\n'}


{'id': 'HP_0040252', 'url': 'http://purl.obolibrary.org/obo/HP_0040252', 'lbl': 'Abnormal size of the clitoris', 'desc': 'label: Abnormal size of the clitoris\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040253', 'url': 'http://purl.obolibrary.org/obo/HP_0040253', 'lbl': 'Increased size of the clitoris', 'desc': 'label: Increased size of the clitoris\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040254', 'url': 'http://purl.obolibrary.org/obo/HP_0040254', 'lbl': 'Decreased size of the clitoris', 'desc': 'label: Decreased size of the clitoris\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040255', 'url': 'http://purl.obolibrary.org/obo/HP_0040255', 'lbl': 'Aplasia/Hypoplasia of the clitoris', 'desc': 'label: Aplasia/Hypoplasia of the clitoris\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040256', 'url': 'http://purl.obolibrary.org/obo/HP_0040256', 'lbl': 'Aplastic/Hypoplastic nasopharyngeal adenoids', 'desc': 'label: Aplastic/Hypoplastic nasopharyngeal adenoids\ndefinition : Absence or underdevelopment of the nasopharyngeal adenoids.\nsynonyms :Adenoids small or absent\n'}


{'id': 'HP_0040257', 'url': 'http://purl.obolibrary.org/obo/HP_0040257', 'lbl': 'Abnormal size of nasopharyngeal adenoids', 'desc': 'label: Abnormal size of nasopharyngeal adenoids\ndefinition : A deviation in the size of nasopharyngeal adenoids.\nsynonyms :\n'}


{'id': 'HP_0040258', 'url': 'http://purl.obolibrary.org/obo/HP_0040258', 'lbl': 'Hypoplastic nasopharyngeal adenoids', 'desc': 'label: Hypoplastic nasopharyngeal adenoids\ndefinition : Underdevelopment of the nasopharyngeal adenoids.\nsynonyms :Underdeveloped nasopharyngeal adenoids\n'}


{'id': 'HP_0040259', 'url': 'http://purl.obolibrary.org/obo/HP_0040259', 'lbl': 'Aplastic nasopharyngeal adenoids', 'desc': 'label: Aplastic nasopharyngeal adenoids\ndefinition : Absence of the nasopharyngeal adenoids as a developmental defect.\nsynonyms :\n'}


{'id': 'HP_0040260', 'url': 'http://purl.obolibrary.org/obo/HP_0040260', 'lbl': 'Decreased size of nasopharyngeal adenoids', 'desc': 'label: Decreased size of nasopharyngeal adenoids\ndefinition : An abnormal decrease in the size of nasopharyngeal adenoids.\nsynonyms :\n'}


{'id': 'HP_0040261', 'url': 'http://purl.obolibrary.org/obo/HP_0040261', 'lbl': 'Increased size of nasopharyngeal adenoids', 'desc': 'label: Increased size of nasopharyngeal adenoids\ndefinition : An abnormal increase in the size of nasopharyngeal adenoids.\nsynonyms :Adenoid hypertrophy; Adenoids large\n'}


{'id': 'HP_0040262', 'url': 'http://purl.obolibrary.org/obo/HP_0040262', 'lbl': 'Glue ear', 'desc': 'label: Glue ear\ndefinition : Middle ear is filled with glue-like fluid instead of air.\nsynonyms :\n'}


{'id': 'HP_0040263', 'url': 'http://purl.obolibrary.org/obo/HP_0040263', 'lbl': 'Jaw ankylosis', 'desc': 'label: Jaw ankylosis\ndefinition : \nsynonyms :Difficulty opening mouth\n'}


{'id': 'HP_0040264', 'url': 'http://purl.obolibrary.org/obo/HP_0040264', 'lbl': 'Jaw pain', 'desc': 'label: Jaw pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the jaw.\nsynonyms :Jaw pain\n'}


{'id': 'HP_0040265', 'url': 'http://purl.obolibrary.org/obo/HP_0040265', 'lbl': 'Upper limb muscle hypertrophy', 'desc': 'label: Upper limb muscle hypertrophy\ndefinition : Abnormal increase in muscle size and mass of one or both arms not due to training.\nsynonyms :\n'}


{'id': 'HP_0040266', 'url': 'http://purl.obolibrary.org/obo/HP_0040266', 'lbl': 'Proximal upper limb muscle hypertrophy', 'desc': 'label: Proximal upper limb muscle hypertrophy\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040267', 'url': 'http://purl.obolibrary.org/obo/HP_0040267', 'lbl': 'Distal upper limb muscle hypertrophy', 'desc': 'label: Distal upper limb muscle hypertrophy\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040268', 'url': 'http://purl.obolibrary.org/obo/HP_0040268', 'lbl': 'Recurrent infections of the middle ear', 'desc': 'label: Recurrent infections of the middle ear\ndefinition : Increased susceptibility to middle ear infections, as manifested by recurrent episodes of middle ear infections\nsynonyms :\n'}


{'id': 'HP_0040269', 'url': 'http://purl.obolibrary.org/obo/HP_0040269', 'lbl': 'Blocked Eustachian tube', 'desc': 'label: Blocked Eustachian tube\ndefinition : \nsynonyms :Obstruction of Eustachian tube\n'}


{'id': 'HP_0040270', 'url': 'http://purl.obolibrary.org/obo/HP_0040270', 'lbl': 'Impaired glucose tolerance', 'desc': 'label: Impaired glucose tolerance\ndefinition : An abnormal resistance to glucose, i.e., a reduction in the ability to maintain glucose levels in the blood stream within normal limits following oral or intravenous administration of glucose.\nsynonyms :Decreased glucose tolerance; Glucose tolerance decreased\n'}


{'id': 'HP_0040272', 'url': 'http://purl.obolibrary.org/obo/HP_0040272', 'lbl': 'Hyperintensity of MRI T2 signal of the spinal cord', 'desc': 'label: Hyperintensity of MRI T2 signal of the spinal cord\ndefinition : A region of high intensity (brightness) observed upon magnetic resonance imaging (MRI) scans of the spinal cord.\nsynonyms :\n'}


{'id': 'HP_0040273', 'url': 'http://purl.obolibrary.org/obo/HP_0040273', 'lbl': 'Adenocarcinoma of the intestines', 'desc': 'label: Adenocarcinoma of the intestines\ndefinition : A malignant epithelial tumor with a glandular organization that originates in the intestines.\nsynonyms :\n'}


{'id': 'HP_0040274', 'url': 'http://purl.obolibrary.org/obo/HP_0040274', 'lbl': 'Adenocarcinoma of the small intestine', 'desc': 'label: Adenocarcinoma of the small intestine\ndefinition : A malignant epithelial tumor with a glandular organization that originates in the small intestine.\nsynonyms :\n'}


{'id': 'HP_0040275', 'url': 'http://purl.obolibrary.org/obo/HP_0040275', 'lbl': 'Adenocarcinoma of the large intestine', 'desc': 'label: Adenocarcinoma of the large intestine\ndefinition : A malignant epithelial tumor with a glandular organization that originates in the large intestine.\nsynonyms :\n'}


{'id': 'HP_0040276', 'url': 'http://purl.obolibrary.org/obo/HP_0040276', 'lbl': 'Adenocarcinoma of the colon', 'desc': 'label: Adenocarcinoma of the colon\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040277', 'url': 'http://purl.obolibrary.org/obo/HP_0040277', 'lbl': 'Neoplasm of the pituitary gland', 'desc': 'label: Neoplasm of the pituitary gland\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040278', 'url': 'http://purl.obolibrary.org/obo/HP_0040278', 'lbl': 'Prolactinoma', 'desc': 'label: Prolactinoma\ndefinition : A benign tumor (adenoma) of the pituitary gland\nsynonyms :\n'}


{'id': 'HP_0040279', 'url': 'http://purl.obolibrary.org/obo/HP_0040279', 'lbl': 'Frequency', 'desc': 'label: Frequency\ndefinition : Class to represent frequency of phenotypic abnormalities within a patient cohort.\nsynonyms :\n'}


{'id': 'HP_0040280', 'url': 'http://purl.obolibrary.org/obo/HP_0040280', 'lbl': 'Obligate', 'desc': 'label: Obligate\ndefinition : Always present, i.e. in 100% of the cases.\nsynonyms :Obligate (100%)\n'}


{'id': 'HP_0040281', 'url': 'http://purl.obolibrary.org/obo/HP_0040281', 'lbl': 'Very frequent', 'desc': 'label: Very frequent\ndefinition : Present in 80% to 99% of the cases.\nsynonyms :Very frequent (99-80%)\n'}


{'id': 'HP_0040282', 'url': 'http://purl.obolibrary.org/obo/HP_0040282', 'lbl': 'Frequent', 'desc': 'label: Frequent\ndefinition : Present in 30% to 79% of the cases.\nsynonyms :Frequent (79-30%)\n'}


{'id': 'HP_0040283', 'url': 'http://purl.obolibrary.org/obo/HP_0040283', 'lbl': 'Occasional', 'desc': 'label: Occasional\ndefinition : Present in 5% to 29% of the cases.\nsynonyms :Occasional (29-5%)\n'}


{'id': 'HP_0040284', 'url': 'http://purl.obolibrary.org/obo/HP_0040284', 'lbl': 'Very rare', 'desc': 'label: Very rare\ndefinition : Present in 1% to 4% of the cases.\nsynonyms :Very rare (<4-1%); Very rare (<4-1%)\n'}


{'id': 'HP_0040285', 'url': 'http://purl.obolibrary.org/obo/HP_0040285', 'lbl': 'Excluded', 'desc': 'label: Excluded\ndefinition : Present in 0% of the cases.\nsynonyms :Excluded (0%)\n'}


{'id': 'HP_0040286', 'url': 'http://purl.obolibrary.org/obo/HP_0040286', 'lbl': 'Abnormal axial muscle morphology', 'desc': 'label: Abnormal axial muscle morphology\ndefinition : A structural anomaly of the muscles of the trunk and head.\nsynonyms :Abnormality of axial muscles\n'}


{'id': 'HP_0040287', 'url': 'http://purl.obolibrary.org/obo/HP_0040287', 'lbl': 'Axial muscle atrophy', 'desc': 'label: Axial muscle atrophy\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040288', 'url': 'http://purl.obolibrary.org/obo/HP_0040288', 'lbl': 'Nasogastric tube feeding', 'desc': 'label: Nasogastric tube feeding\ndefinition : The condition of inability to eat normally treated by placement of a thin tube through the nose into the stomach that is then used to carry food.\nsynonyms :\n'}


{'id': 'HP_0040289', 'url': 'http://purl.obolibrary.org/obo/HP_0040289', 'lbl': 'Cyclic neutropenia', 'desc': 'label: Cyclic neutropenia\ndefinition : Recurrent episodes of abnormally low levels of neutrophils in the body (neutropenia).\nsynonyms :CyN\n'}


{'id': 'HP_0040290', 'url': 'http://purl.obolibrary.org/obo/HP_0040290', 'lbl': 'obsolete Abnormality of skeletal muscles', 'desc': 'label: obsolete Abnormality of skeletal muscles\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040291', 'url': 'http://purl.obolibrary.org/obo/HP_0040291', 'lbl': 'Skeletal muscle steatosis', 'desc': 'label: Skeletal muscle steatosis\ndefinition : \nsynonyms :Steatosis of skeletal muscle; Steatosis of skeletal muscles\n'}


{'id': 'HP_0040292', 'url': 'http://purl.obolibrary.org/obo/HP_0040292', 'lbl': 'Left hemiplegia', 'desc': 'label: Left hemiplegia\ndefinition : \nsynonyms :Hemiplegia (left)\n'}


{'id': 'HP_0040293', 'url': 'http://purl.obolibrary.org/obo/HP_0040293', 'lbl': 'Right hemiplegia', 'desc': 'label: Right hemiplegia\ndefinition : \nsynonyms :Hemiplegia (right)\n'}


{'id': 'HP_0040294', 'url': 'http://purl.obolibrary.org/obo/HP_0040294', 'lbl': 'Duplicated tongue', 'desc': 'label: Duplicated tongue\ndefinition : \nsynonyms :Duplication of tongue; Tongue duplicated; Tongue duplication\n'}


{'id': 'HP_0040295', 'url': 'http://purl.obolibrary.org/obo/HP_0040295', 'lbl': 'Duplication of the upper lip', 'desc': 'label: Duplication of the upper lip\ndefinition : \nsynonyms :Double upper lip\n'}


{'id': 'HP_0040296', 'url': 'http://purl.obolibrary.org/obo/HP_0040296', 'lbl': 'Abnormal location of the eyebrow', 'desc': 'label: Abnormal location of the eyebrow\ndefinition : Anomalous anatomical placement of the eyebrow.\nsynonyms :Abnormal location of eyebrows; Abnormally placed eyebrows\n'}


{'id': 'HP_0040297', 'url': 'http://purl.obolibrary.org/obo/HP_0040297', 'lbl': 'Preauricular cyst', 'desc': 'label: Preauricular cyst\ndefinition : Preauricular sinus is an occasional finding and most frequently appears as a small pit close to the anterior margin of the ascending portion of the helix. The opening has also been reported along the postero superior margin of the helix, the tragus or the lobule. Preauricular sinus may lead to the formation of a subcutaneous cyst that is intimately related to the tragal cartilage and the anterior crus of the helix.\nsynonyms :\n'}


{'id': 'HP_0040298', 'url': 'http://purl.obolibrary.org/obo/HP_0040298', 'lbl': 'Hyperplasia of the endometrium', 'desc': 'label: Hyperplasia of the endometrium\ndefinition : \nsynonyms :Hyperplastic endometrium\n'}


{'id': 'HP_0040299', 'url': 'http://purl.obolibrary.org/obo/HP_0040299', 'lbl': 'Decreased circulating free fatty acid level', 'desc': 'label: Decreased circulating free fatty acid level\ndefinition : \nsynonyms :Low fatty acids level\n'}


{'id': 'HP_0040300', 'url': 'http://purl.obolibrary.org/obo/HP_0040300', 'lbl': 'Abnormal circulating free fatty acid concentration', 'desc': 'label: Abnormal circulating free fatty acid concentration\ndefinition : Any deviation from the normal concentration of a free fatty acid in the blood circulation.\nsynonyms :Abnormal circulating free fatty acid level\n'}


{'id': 'HP_0040301', 'url': 'http://purl.obolibrary.org/obo/HP_0040301', 'lbl': 'Increased urinary glycerol', 'desc': 'label: Increased urinary glycerol\ndefinition : An increased concentration of glycerol in the urine.\nsynonyms :\n'}


{'id': 'HP_0040302', 'url': 'http://purl.obolibrary.org/obo/HP_0040302', 'lbl': 'Hyperglycerolemia', 'desc': 'label: Hyperglycerolemia\ndefinition : Increased concentration of glycerol in the blood.\nsynonyms :Pseudohypertriglyceridemia\n'}


{'id': 'HP_0040303', 'url': 'http://purl.obolibrary.org/obo/HP_0040303', 'lbl': 'Decreased serum iron', 'desc': 'label: Decreased serum iron\ndefinition : \nsynonyms :Low serum iron\n'}


{'id': 'HP_0040304', 'url': 'http://purl.obolibrary.org/obo/HP_0040304', 'lbl': 'Duplication of the sella turcica', 'desc': 'label: Duplication of the sella turcica\ndefinition : \nsynonyms :Duplicate sella turcica; Duplicated sella turcica\n'}


{'id': 'HP_0040305', 'url': 'http://purl.obolibrary.org/obo/HP_0040305', 'lbl': 'Increased male libido', 'desc': 'label: Increased male libido\ndefinition : Increased desire for sexual activity on the part of a male.\nsynonyms :\n'}


{'id': 'HP_0040306', 'url': 'http://purl.obolibrary.org/obo/HP_0040306', 'lbl': 'Decreased male libido', 'desc': 'label: Decreased male libido\ndefinition : Reduced desire for sexual activity on the part of a male.\nsynonyms :\n'}


{'id': 'HP_0040307', 'url': 'http://purl.obolibrary.org/obo/HP_0040307', 'lbl': 'Male sexual dysfunction', 'desc': 'label: Male sexual dysfunction\ndefinition : A problem occurring during any phase of the male sexual response cycle that prevents the individual from experiencing satisfaction from the sexual activity\nsynonyms :\n'}


{'id': 'HP_0040308', 'url': 'http://purl.obolibrary.org/obo/HP_0040308', 'lbl': 'Male anorgasmia', 'desc': 'label: Male anorgasmia\ndefinition : Inability of a male to reach orgasm.\nsynonyms :\n'}


{'id': 'HP_0040309', 'url': 'http://purl.obolibrary.org/obo/HP_0040309', 'lbl': 'Increased size of the mandible', 'desc': 'label: Increased size of the mandible\ndefinition : \nsynonyms :Large jaw\n'}


{'id': 'HP_0040310', 'url': 'http://purl.obolibrary.org/obo/HP_0040310', 'lbl': 'Sterile arthritis', 'desc': 'label: Sterile arthritis\ndefinition : An inflammatory arthritis characterized by purulent synovial fluid with neutrophil accumulation, but with negative cultures.\nsynonyms :\n'}


{'id': 'HP_0040311', 'url': 'http://purl.obolibrary.org/obo/HP_0040311', 'lbl': 'Symmetric polyarthritis', 'desc': 'label: Symmetric polyarthritis\ndefinition : Polyarthritis refers to a joint disease that involves at least five joints. One or more signs of inflammation, including pain, movement restriction, swelling, warmth, and redness, are seen in the joints involved. Polyarthritis is defined as symmetric if at least half of the joints involved are affected in a symmetric (i.e., both right and the left) fashion.\nsynonyms :\n'}


{'id': 'HP_0040312', 'url': 'http://purl.obolibrary.org/obo/HP_0040312', 'lbl': 'Temporomandibular arthritis', 'desc': 'label: Temporomandibular arthritis\ndefinition : \nsynonyms :Arthritis of temporomandibular joint\n'}


{'id': 'HP_0040313', 'url': 'http://purl.obolibrary.org/obo/HP_0040313', 'lbl': 'Oligoarthritis', 'desc': 'label: Oligoarthritis\ndefinition : A type of arthritis that affects up to four joints in the first six months of disease.\nsynonyms :\n'}


{'id': 'HP_0040314', 'url': 'http://purl.obolibrary.org/obo/HP_0040314', 'lbl': 'Blind vagina', 'desc': 'label: Blind vagina\ndefinition : The vagina ends in a blind pouch or sac rather than being connected to the internal genitalia.\nsynonyms :Blind-ended vagina\n'}


{'id': 'HP_0040315', 'url': 'http://purl.obolibrary.org/obo/HP_0040315', 'lbl': 'Tongue edema', 'desc': 'label: Tongue edema\ndefinition : An abnormal accumulation of fluid and swelling in the tongue.\nsynonyms :Tongue oedema\n'}


{'id': 'HP_0040316', 'url': 'http://purl.obolibrary.org/obo/HP_0040316', 'lbl': 'obsolete Aplasia of the penis', 'desc': 'label: obsolete Aplasia of the penis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040317', 'url': 'http://purl.obolibrary.org/obo/HP_0040317', 'lbl': 'Blue urine', 'desc': 'label: Blue urine\ndefinition : An abnormal blue color of the urine.\nsynonyms :\n'}


{'id': 'HP_0040318', 'url': 'http://purl.obolibrary.org/obo/HP_0040318', 'lbl': 'Red urine', 'desc': 'label: Red urine\ndefinition : An abnormal red color of the urine.\nsynonyms :\n'}


{'id': 'HP_0040319', 'url': 'http://purl.obolibrary.org/obo/HP_0040319', 'lbl': 'Dark urine', 'desc': 'label: Dark urine\ndefinition : An abnormal dark color of the urine.\nsynonyms :\n'}


{'id': 'HP_0040320', 'url': 'http://purl.obolibrary.org/obo/HP_0040320', 'lbl': 'Red-brown urine', 'desc': 'label: Red-brown urine\ndefinition : An abnormal red-brown color of the urine.\nsynonyms :red brown urine\n'}


{'id': 'HP_0040321', 'url': 'http://purl.obolibrary.org/obo/HP_0040321', 'lbl': 'Dark yellow urine', 'desc': 'label: Dark yellow urine\ndefinition : An abnormal dark-yellow color of the urine.\nsynonyms :\n'}


{'id': 'HP_0040322', 'url': 'http://purl.obolibrary.org/obo/HP_0040322', 'lbl': 'Purple urine', 'desc': 'label: Purple urine\ndefinition : An abnormal purple color of the urine.\nsynonyms :\n'}


{'id': 'HP_0040323', 'url': 'http://purl.obolibrary.org/obo/HP_0040323', 'lbl': 'Erythema of the eyelids', 'desc': 'label: Erythema of the eyelids\ndefinition : Redness of the skin of the eyelids, caused by hyperemia of the capillaries in the lower layers of the skin.\nsynonyms :Erythema of eyelid; Eyelid erythema\n'}


{'id': 'HP_0040324', 'url': 'http://purl.obolibrary.org/obo/HP_0040324', 'lbl': 'Heliotrope rash', 'desc': 'label: Heliotrope rash\ndefinition : In a heliotrope rash, the color of the skin turns to violet, which is the color of the heliotrope flower.\nsynonyms :Heliotrope erythema\n'}


{'id': 'HP_0040325', 'url': 'http://purl.obolibrary.org/obo/HP_0040325', 'lbl': "Bull's eye rash", 'desc': "label: Bull's eye rash\ndefinition : A cutaneous eruption that consists of multiple (at least two) concentric erythematous rings.\nsynonyms :\n"}


{'id': 'HP_0040326', 'url': 'http://purl.obolibrary.org/obo/HP_0040326', 'lbl': 'Hypoplasia of the olfactory bulb', 'desc': 'label: Hypoplasia of the olfactory bulb\ndefinition : Underdevelopment of the olfactory bulb.\nsynonyms :Hypoplasia of olfactory bulb; Hypoplastic olfactory bulb\n'}


{'id': 'HP_0040327', 'url': 'http://purl.obolibrary.org/obo/HP_0040327', 'lbl': 'Abnormal morphology of the olfactory bulb', 'desc': 'label: Abnormal morphology of the olfactory bulb\ndefinition : An abnormal morphology of the olfactory bulb (bulbus olfactorius), which is involved in olfaction, i.e. the sense of smell.\nsynonyms :\n'}


{'id': 'HP_0040328', 'url': 'http://purl.obolibrary.org/obo/HP_0040328', 'lbl': 'Focal hyperintensity of cerebral white matter on MRI', 'desc': 'label: Focal hyperintensity of cerebral white matter on MRI\ndefinition : An abnormal area of increased brightness (hyperintensity) that is limited to one particular area.\nsynonyms :\n'}


{'id': 'HP_0040329', 'url': 'http://purl.obolibrary.org/obo/HP_0040329', 'lbl': 'Multifocal hyperintensity of cerebral white matter on MRI', 'desc': 'label: Multifocal hyperintensity of cerebral white matter on MRI\ndefinition : An abnormal area of increased brightness (hyperintensity) that occurs in several distinct areas.\nsynonyms :\n'}


{'id': 'HP_0040330', 'url': 'http://purl.obolibrary.org/obo/HP_0040330', 'lbl': 'Confluent hyperintensity of cerebral white matter on MRI', 'desc': 'label: Confluent hyperintensity of cerebral white matter on MRI\ndefinition : Areas of brighter than expected MRI signal in the white matter of the brain whereby individual patches run together.\nsynonyms :\n'}


{'id': 'HP_0040331', 'url': 'http://purl.obolibrary.org/obo/HP_0040331', 'lbl': 'Focal hypointensity of cerebral white matter on MRI', 'desc': 'label: Focal hypointensity of cerebral white matter on MRI\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040332', 'url': 'http://purl.obolibrary.org/obo/HP_0040332', 'lbl': 'Multifocal hypointensity of cerebral white matter on MRI', 'desc': 'label: Multifocal hypointensity of cerebral white matter on MRI\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040333', 'url': 'http://purl.obolibrary.org/obo/HP_0040333', 'lbl': 'Confluent hypointensity of cerebral white matter on MRI', 'desc': 'label: Confluent hypointensity of cerebral white matter on MRI\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0040334', 'url': 'http://purl.obolibrary.org/obo/HP_0040334', 'lbl': 'Purulent rhinitis', 'desc': 'label: Purulent rhinitis\ndefinition : Chronic rhinitis accompanied by pus formation.\nsynonyms :\n'}


{'id': 'HP_0041042', 'url': 'http://purl.obolibrary.org/obo/HP_0041042', 'lbl': 'Absent neutrophil lactoferrin', 'desc': 'label: Absent neutrophil lactoferrin\ndefinition : The absence of lactoferrin in neutrophil granules, which could be caused by either an isolated failure of synthesis of this protein (or the production of an antigenically unrecognizable form of lactoferrin) or a complete deficiency of specific granule production.\nsynonyms :\n'}


{'id': 'HP_0041043', 'url': 'http://purl.obolibrary.org/obo/HP_0041043', 'lbl': 'Neutrophil nuclear clefts', 'desc': 'label: Neutrophil nuclear clefts\ndefinition : An abnormality of the nucleus of neutrophils, which presents as either a type I nuclear cleft, where the nuclear cleft may show a transition into a round/oval shape. The second type nuclear cleft, which runs perpendicular to the nuclear surface, and this type of cleft might be related to nuclear lobe formation.\nsynonyms :\n'}


{'id': 'HP_0041044', 'url': 'http://purl.obolibrary.org/obo/HP_0041044', 'lbl': 'Low neutrophil alkaline phosphatase', 'desc': 'label: Low neutrophil alkaline phosphatase\ndefinition : An abnormally reduced level of alkaline phosphatase in neutrophils, which could be due to absence of enzyme or the production of defective enzyme.\nsynonyms :\n'}


{'id': 'HP_0041045', 'url': 'http://purl.obolibrary.org/obo/HP_0041045', 'lbl': 'Increased neutrophil mitochondria', 'desc': 'label: Increased neutrophil mitochondria\ndefinition : An increased number of mitochondria detected in neutrophils.\nsynonyms :\n'}


{'id': 'HP_0041046', 'url': 'http://purl.obolibrary.org/obo/HP_0041046', 'lbl': 'Increased neutrophil ribosomes', 'desc': 'label: Increased neutrophil ribosomes\ndefinition : An increased number of ribosomes detected in neutrophils.\nsynonyms :\n'}


{'id': 'HP_0041047', 'url': 'http://purl.obolibrary.org/obo/HP_0041047', 'lbl': 'Bladder outlet obstruction', 'desc': 'label: Bladder outlet obstruction\ndefinition : A compression or resistance upon the bladder outflow channel at any location from the bladder neck to urethral meatus, which usually causes lower urinary tract symptoms (LUTS).\nsynonyms :Obstruction of bladder outlet\n'}


{'id': 'HP_0041048', 'url': 'http://purl.obolibrary.org/obo/HP_0041048', 'lbl': 'Decreased expression of GPI-anchored proteins on the cell surface', 'desc': 'label: Decreased expression of GPI-anchored proteins on the cell surface\ndefinition : A decrease in the protein expression of GPI-anchor proteins, such as CD55 and CD59, at the cell surface, which suggests a defect in GPI-anchor biosynthesis.\nsynonyms :\n'}


{'id': 'HP_0041049', 'url': 'http://purl.obolibrary.org/obo/HP_0041049', 'lbl': 'Starch intolerance', 'desc': 'label: Starch intolerance\ndefinition : An inability to digest starch.\nsynonyms :Amylose-amylopectin intolerance; Starch intolerance\n'}


{'id': 'HP_0041050', 'url': 'http://purl.obolibrary.org/obo/HP_0041050', 'lbl': 'Renal tubular cyst', 'desc': 'label: Renal tubular cyst\ndefinition : Tubular lumnal dilatation/prominence lined by simple layer of cuboidal-to-flat tublar epihelial cells.\nsynonyms :Renal tubule cyst\n'}


{'id': 'HP_0041051', 'url': 'http://purl.obolibrary.org/obo/HP_0041051', 'lbl': 'Ageusia', 'desc': 'label: Ageusia\ndefinition : A rare condition that is characterized by a complete loss of taste function of the tongue.\nsynonyms :Absent sense of taste; Impaired taste sensation; Lost taste\n'}


{'id': 'HP_0041052', 'url': 'http://purl.obolibrary.org/obo/HP_0041052', 'lbl': 'Agenesis of putamen', 'desc': 'label: Agenesis of putamen\ndefinition : A developmental defect characterized by the absence of the putamen owing to its failure to develop.\nsynonyms :\n'}


{'id': 'HP_0041053', 'url': 'http://purl.obolibrary.org/obo/HP_0041053', 'lbl': 'obsolete Fractured head', 'desc': 'label: obsolete Fractured head\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0041054', 'url': 'http://purl.obolibrary.org/obo/HP_0041054', 'lbl': 'obsolete Fractured thoracic segment of trunk', 'desc': 'label: obsolete Fractured thoracic segment of trunk\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0041055', 'url': 'http://purl.obolibrary.org/obo/HP_0041055', 'lbl': 'Fractured humerus', 'desc': 'label: Fractured humerus\ndefinition : A partial or complete breakage of the humerus.\nsynonyms :Broken humerus; Fracture of the humerus; Humeral fracture; Humerus fracture; bone humerus\n'}


{'id': 'HP_0041056', 'url': 'http://purl.obolibrary.org/obo/HP_0041056', 'lbl': 'Hot cross bun sign', 'desc': 'label: Hot cross bun sign\ndefinition : A cruciform-shaped hyperintensity within the pons found on T2-weighted magnetic resonance imaging (MRI).\nsynonyms :\n'}


{'id': 'HP_0041057', 'url': 'http://purl.obolibrary.org/obo/HP_0041057', 'lbl': 'Transient decreased circulating IgG4', 'desc': 'label: Transient decreased circulating IgG4\ndefinition : A temporary reduction beneath the normal level of total immunoglobulin G4 (IgG4) in the blood circulation.\nsynonyms :Transient decreased IgG4 in blood\n'}


{'id': 'HP_0041058', 'url': 'http://purl.obolibrary.org/obo/HP_0041058', 'lbl': 'Chronic decreased circulating IgG4', 'desc': 'label: Chronic decreased circulating IgG4\ndefinition : A lasting decrease of immunoglobulin G4 (IgG4) in the blood.\nsynonyms :Chronic decreased IgG4 in blood\n'}


{'id': 'HP_0041059', 'url': 'http://purl.obolibrary.org/obo/HP_0041059', 'lbl': 'Chronic (near) absent circulating IgG4', 'desc': 'label: Chronic (near) absent circulating IgG4\ndefinition : A lasting absence of immunoglobulin G4 (IgG4) in the blood, whereby at most trace quantities of IgG4 can be measured.\nsynonyms :Chronic (near) absent IgG4 in blood\n'}


{'id': 'HP_0041060', 'url': 'http://purl.obolibrary.org/obo/HP_0041060', 'lbl': 'Chronic partially decreased circulating IgG4', 'desc': 'label: Chronic partially decreased circulating IgG4\ndefinition : A lasting limited decrease of immunoglobulin G4 (IgG4) in the blood.\nsynonyms :Chronic partially decreased IgG4 in blood\n'}


{'id': 'HP_0041061', 'url': 'http://purl.obolibrary.org/obo/HP_0041061', 'lbl': 'Fractured calcaneus', 'desc': 'label: Fractured calcaneus\ndefinition : A partial or complete breakage of the calcaneus.\nsynonyms :bone calcaneus\n'}


{'id': 'HP_0041062', 'url': 'http://purl.obolibrary.org/obo/HP_0041062', 'lbl': 'Transient decreased circulating IgG2', 'desc': 'label: Transient decreased circulating IgG2\ndefinition : A temporary reduction beneath the normal level of total immunoglobulin G2 (IgG2) in the blood circulation.\nsynonyms :Transient decreased IgG2 in blood\n'}


{'id': 'HP_0041063', 'url': 'http://purl.obolibrary.org/obo/HP_0041063', 'lbl': 'Chronic decreased cirulating IgG2', 'desc': 'label: Chronic decreased cirulating IgG2\ndefinition : A lasting decrease of immunoglobulin G2 (IgG2) in the blood.\nsynonyms :Chronic decreased IgG2 in blood\n'}


{'id': 'HP_0041064', 'url': 'http://purl.obolibrary.org/obo/HP_0041064', 'lbl': 'Fractured knee', 'desc': 'label: Fractured knee\ndefinition : A partial or complete breakage of the knee.\nsynonyms :bone knee\n'}


{'id': 'HP_0041065', 'url': 'http://purl.obolibrary.org/obo/HP_0041065', 'lbl': 'Chronic (near) absent circulating IgG2', 'desc': 'label: Chronic (near) absent circulating IgG2\ndefinition : A lasting absence of immunoglobulin G2 (IgG2) in the blood, whereby at most trace quantities of IgG2 can be measured.\nsynonyms :Chronic (near) absent IgG2 in blood\n'}


{'id': 'HP_0041066', 'url': 'http://purl.obolibrary.org/obo/HP_0041066', 'lbl': 'Chronic partially decreased circulating IgG2', 'desc': 'label: Chronic partially decreased circulating IgG2\ndefinition : A lasting limited decrease of immunoglobulin G2 (IgG2) in the blood.\nsynonyms :Chronic partially decreased IgG2 in blood\n'}


{'id': 'HP_0041067', 'url': 'http://purl.obolibrary.org/obo/HP_0041067', 'lbl': 'Transient decreased circulating IgG1', 'desc': 'label: Transient decreased circulating IgG1\ndefinition : A temporary reduction beneath the normal level of total immunoglobulin G1 (IgG1) in the blood circulation.\nsynonyms :Transient decreased IgG1 in blood\n'}


{'id': 'HP_0041068', 'url': 'http://purl.obolibrary.org/obo/HP_0041068', 'lbl': 'Chronic decreased circulating IgG1', 'desc': 'label: Chronic decreased circulating IgG1\ndefinition : A lasting decrease of immunoglobulin G1 (IgG1) in the blood.\nsynonyms :Chronic decreased IgG1 in blood\n'}


{'id': 'HP_0041069', 'url': 'http://purl.obolibrary.org/obo/HP_0041069', 'lbl': 'Chronic (near) absent circulating IgG1', 'desc': 'label: Chronic (near) absent circulating IgG1\ndefinition : A lasting absence of immunoglobulin G1 (IgG1) in the blood, whereby at most trace quantities of IgG1 can be measured.\nsynonyms :Chronic (near) absent IgG1 in blood\n'}


{'id': 'HP_0041070', 'url': 'http://purl.obolibrary.org/obo/HP_0041070', 'lbl': 'Chronic partially decreased circulating IgG1', 'desc': 'label: Chronic partially decreased circulating IgG1\ndefinition : A lasting limited decrease of immunoglobulin G1 (IgG1) in the blood.\nsynonyms :Chronic partially decreased IgG1 in blood\n'}


{'id': 'HP_0041071', 'url': 'http://purl.obolibrary.org/obo/HP_0041071', 'lbl': 'Transient decreased circulating IgG3', 'desc': 'label: Transient decreased circulating IgG3\ndefinition : A temporary reduction beneath the normal level of total immunoglobulin G3 (IgG3) in the blood circulation.\nsynonyms :Transient decreased IgG3 in blood\n'}


{'id': 'HP_0041072', 'url': 'http://purl.obolibrary.org/obo/HP_0041072', 'lbl': 'Chronic decreased circulating IgG3', 'desc': 'label: Chronic decreased circulating IgG3\ndefinition : A lasting decrease of immunoglobulin G3 (IgG3) in the blood.\nsynonyms :Chronic decreased IgG3 in blood\n'}


{'id': 'HP_0041073', 'url': 'http://purl.obolibrary.org/obo/HP_0041073', 'lbl': 'Fractured thoracic vertebra', 'desc': 'label: Fractured thoracic vertebra\ndefinition : A partial or complete breakage of the thoracic vertebra.\nsynonyms :bone thoracic vertebra\n'}


{'id': 'HP_0041074', 'url': 'http://purl.obolibrary.org/obo/HP_0041074', 'lbl': 'Chronic (near) absent circulating IgG3', 'desc': 'label: Chronic (near) absent circulating IgG3\ndefinition : A lasting absence of immunoglobulin G3 (IgG3) in the blood, whereby at most trace quantities of IgG3 can be measured.\nsynonyms :Chronic (near) absent IgG3 in blood\n'}


{'id': 'HP_0041075', 'url': 'http://purl.obolibrary.org/obo/HP_0041075', 'lbl': 'Chronic partially decreased circulating IgG3', 'desc': 'label: Chronic partially decreased circulating IgG3\ndefinition : A lasting limited decrease of immunoglobulin G3 (IgG3) in the blood.\nsynonyms :Chronic partially decreased IgG3 in blood\n'}


{'id': 'HP_0041076', 'url': 'http://purl.obolibrary.org/obo/HP_0041076', 'lbl': 'Abnormal immunoglobulin level in body fluid', 'desc': 'label: Abnormal immunoglobulin level in body fluid\ndefinition : An abnormal deviation from normal levels of immunoglobulins in body fluids, such as mucous.\nsynonyms :\n'}


{'id': 'HP_0041077', 'url': 'http://purl.obolibrary.org/obo/HP_0041077', 'lbl': 'Increased immunoglobulin level in body fluid', 'desc': 'label: Increased immunoglobulin level in body fluid\ndefinition : An elevation from normal levels of immunoglobulins in body fluids, such as mucous.\nsynonyms :\n'}


{'id': 'HP_0041078', 'url': 'http://purl.obolibrary.org/obo/HP_0041078', 'lbl': 'Decreased immunoglobulin level in body fluid', 'desc': 'label: Decreased immunoglobulin level in body fluid\ndefinition : An reduction from normal levels of immunoglobulins in body fluids, such as mucous.\nsynonyms :\n'}


{'id': 'HP_0041079', 'url': 'http://purl.obolibrary.org/obo/HP_0041079', 'lbl': 'Decreased body fat percentage', 'desc': 'label: Decreased body fat percentage\ndefinition : The percentage of fat as a part of total body weight below the norm, usually defined as less than 14% for females and less than 8% for males.\nsynonyms :Decreased adipose tissue percentage\n'}


{'id': 'HP_0041080', 'url': 'http://purl.obolibrary.org/obo/HP_0041080', 'lbl': 'Abnormal proportion of exhausted T cells', 'desc': 'label: Abnormal proportion of exhausted T cells\ndefinition : A deviation from the normal proportion of exhausted T cell relative to T cell in the blood.\nsynonyms :\n'}


{'id': 'HP_0041081', 'url': 'http://purl.obolibrary.org/obo/HP_0041081', 'lbl': 'Fractured lower leg', 'desc': 'label: Fractured lower leg\ndefinition : Bone fracture anywhere in the tibia, fibula, or ankle.\nsynonyms :Fracture of the lower leg; Lower extremity fracture; Lower limb fracture\n'}


{'id': 'HP_0041082', 'url': 'http://purl.obolibrary.org/obo/HP_0041082', 'lbl': 'Fractured skull', 'desc': 'label: Fractured skull\ndefinition : A partial or complete breakage of the skull.\nsynonyms :\n'}


{'id': 'HP_0041083', 'url': 'http://purl.obolibrary.org/obo/HP_0041083', 'lbl': 'Fractured phalanx', 'desc': 'label: Fractured phalanx\ndefinition : A partial or complete breakage of the phalanx.\nsynonyms :bone phalanx\n'}