{'id': 'HP_0004035', 'url': 'http://purl.obolibrary.org/obo/HP_0004035', 'lbl': 'Abnormal ulnar styloid process morphology', 'desc': 'label: Abnormal ulnar styloid process morphology\ndefinition : \nsynonyms :Abnormality of the styloid process of ulna\n'}


{'id': 'HP_0004036', 'url': 'http://purl.obolibrary.org/obo/HP_0004036', 'lbl': 'Long styloid process of ulna', 'desc': 'label: Long styloid process of ulna\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004037', 'url': 'http://purl.obolibrary.org/obo/HP_0004037', 'lbl': 'Abnormal ulnar epiphysis morphology', 'desc': 'label: Abnormal ulnar epiphysis morphology\ndefinition : \nsynonyms :Abnormality of the epiphyseal plate of the ulna; Abnormality of the ulnar epiphyses\n'}


{'id': 'HP_0004038', 'url': 'http://purl.obolibrary.org/obo/HP_0004038', 'lbl': 'obsolete Bony spicule of ulnar epiphyseal plate', 'desc': 'label: obsolete Bony spicule of ulnar epiphyseal plate\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004039', 'url': 'http://purl.obolibrary.org/obo/HP_0004039', 'lbl': 'Abnormal ulnar metaphysis morphology', 'desc': 'label: Abnormal ulnar metaphysis morphology\ndefinition : Any structural abnormality of the portion of the ulna between the epiphysis and the diaphysis.\nsynonyms :Abnormality of ulnar metaphysis\n'}


{'id': 'HP_0004040', 'url': 'http://purl.obolibrary.org/obo/HP_0004040', 'lbl': 'Corner fragments of ulnar metaphysis', 'desc': 'label: Corner fragments of ulnar metaphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004041', 'url': 'http://purl.obolibrary.org/obo/HP_0004041', 'lbl': 'Cupped ulnar metaphysis', 'desc': 'label: Cupped ulnar metaphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004042', 'url': 'http://purl.obolibrary.org/obo/HP_0004042', 'lbl': 'Ulnar metaphyseal irregularity', 'desc': 'label: Ulnar metaphyseal irregularity\ndefinition : Irregularity of the normally smooth surface of the metaphysis of the ulna.\nsynonyms :Irregular ulnar metaphysis\n'}


{'id': 'HP_0004043', 'url': 'http://purl.obolibrary.org/obo/HP_0004043', 'lbl': 'Lytic defects of ulnar metaphysis', 'desc': 'label: Lytic defects of ulnar metaphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004044', 'url': 'http://purl.obolibrary.org/obo/HP_0004044', 'lbl': 'Pointed ulnar metaphysis', 'desc': 'label: Pointed ulnar metaphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004045', 'url': 'http://purl.obolibrary.org/obo/HP_0004045', 'lbl': 'Sloping ulnar metaphysis', 'desc': 'label: Sloping ulnar metaphysis\ndefinition : A sloped configuration of the metaphysis (shaft) of the ulna.\nsynonyms :\n'}


{'id': 'HP_0004046', 'url': 'http://purl.obolibrary.org/obo/HP_0004046', 'lbl': 'Spurred ulnar metaphysis', 'desc': 'label: Spurred ulnar metaphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004047', 'url': 'http://purl.obolibrary.org/obo/HP_0004047', 'lbl': 'Wide ulnar metaphysis', 'desc': 'label: Wide ulnar metaphysis\ndefinition : Increase in width (breadth) of the ulnar metaphysis.\nsynonyms :Broad ulnar metaphysis\n'}


{'id': 'HP_0004048', 'url': 'http://purl.obolibrary.org/obo/HP_0004048', 'lbl': 'Narrow joint spaces of wrist', 'desc': 'label: Narrow joint spaces of wrist\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004049', 'url': 'http://purl.obolibrary.org/obo/HP_0004049', 'lbl': 'Decreased carpal angles of wrist', 'desc': 'label: Decreased carpal angles of wrist\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004050', 'url': 'http://purl.obolibrary.org/obo/HP_0004050', 'lbl': 'Absent hand', 'desc': 'label: Absent hand\ndefinition : The total absence of the hand, with no bony elements distal to the radius or ulna.\nsynonyms :Absent hand; Acheiria\n'}


{'id': 'HP_0004051', 'url': 'http://purl.obolibrary.org/obo/HP_0004051', 'lbl': 'Advanced ossification of the hand bones', 'desc': 'label: Advanced ossification of the hand bones\ndefinition : Ossification of hand bones at an earlier age than normal.\nsynonyms :Accelerated maturation of hand bones; Advanced maturation of the hand bones\n'}


{'id': 'HP_0004052', 'url': 'http://purl.obolibrary.org/obo/HP_0004052', 'lbl': 'Delayed ossification of the hand bones', 'desc': 'label: Delayed ossification of the hand bones\ndefinition : Ossification of hand bones is less advanced than would be expected according to age-adjusted norms.\nsynonyms :Delay maturation/delayed ossification of the hand; Delayed maturation of the hand bones\n'}


{'id': 'HP_0004053', 'url': 'http://purl.obolibrary.org/obo/HP_0004053', 'lbl': 'Dysharmonic maturation of the hand bones', 'desc': 'label: Dysharmonic maturation of the hand bones\ndefinition : Pattern of hand-wrist development does not fit the normal sequence of ossification of the individual bones of the hand.\nsynonyms :Disharmonic maturation of the hand bones; Dysharmonic ossification of the hand bones\n'}


{'id': 'HP_0004054', 'url': 'http://purl.obolibrary.org/obo/HP_0004054', 'lbl': 'Sclerosis of hand bone', 'desc': 'label: Sclerosis of hand bone\ndefinition : Osteosclerosis affecting one or more bones of the hand.\nsynonyms :Generalised sclerosis of hand bones; Generalized sclerosis of hand bones; Hand bone sclerosis; Increased bone density in hand bone; Increased bone density in hand bones\n'}


{'id': 'HP_0004057', 'url': 'http://purl.obolibrary.org/obo/HP_0004057', 'lbl': 'Mitten deformity', 'desc': 'label: Mitten deformity\ndefinition : Fusion of the hands and feet by a thin membrane of skin (scarring) seen in forms of dystrophic epidermolysis bullosa and leading to a "mitten" hand deformity.\nsynonyms :Pseudosyndactyly\n'}


{'id': 'HP_0004058', 'url': 'http://purl.obolibrary.org/obo/HP_0004058', 'lbl': 'Hand monodactyly', 'desc': 'label: Hand monodactyly\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004059', 'url': 'http://purl.obolibrary.org/obo/HP_0004059', 'lbl': 'Radial club hand', 'desc': 'label: Radial club hand\ndefinition : Wrist is bent inward toward the thumb because of a congenital defect associated with shortening or absence of the radius.\nsynonyms :\n'}


{'id': 'HP_0004060', 'url': 'http://purl.obolibrary.org/obo/HP_0004060', 'lbl': 'Trident hand', 'desc': 'label: Trident hand\ndefinition : A hand in which the fingers are of nearly equal length and deflected at the first interphalangeal joint, so as to give a forklike shape consisting of separation of the first and second as well as the third and fourth digits.\nsynonyms :trident abnormality; trident deformity\n'}


{'id': 'HP_0004066', 'url': 'http://purl.obolibrary.org/obo/HP_0004066', 'lbl': 'obsolete Laterally deviated thumb phalanges', 'desc': 'label: obsolete Laterally deviated thumb phalanges\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004083', 'url': 'http://purl.obolibrary.org/obo/HP_0004083', 'lbl': 'obsolete Laterally deviated terminal thumb phalanx', 'desc': 'label: obsolete Laterally deviated terminal thumb phalanx\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004090', 'url': 'http://purl.obolibrary.org/obo/HP_0004090', 'lbl': 'obsolete Advanced maturation/advanced ossification of terminal thumb phalanx epiphysis', 'desc': 'label: obsolete Advanced maturation/advanced ossification of terminal thumb phalanx epiphysis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004095', 'url': 'http://purl.obolibrary.org/obo/HP_0004095', 'lbl': 'Curved fingers', 'desc': 'label: Curved fingers\ndefinition : \nsynonyms :Curved fingers\n'}


{'id': 'HP_0004097', 'url': 'http://purl.obolibrary.org/obo/HP_0004097', 'lbl': 'Deviation of finger', 'desc': 'label: Deviation of finger\ndefinition : Deviated fingers is a term that should be used if one or more fingers of the hand are deviated from their normal position, either to the radial or ulnar side. A deviation of a finger can be caused by an abnormal form of one or more of the phalanges of the affected finger, or by a deviation or displacement of one or more phalanges.\nsynonyms :Atypical position of finger; Deviated fingers; Finger pointing in a different direction than usual\n'}


{'id': 'HP_0004099', 'url': 'http://purl.obolibrary.org/obo/HP_0004099', 'lbl': 'Macrodactyly', 'desc': 'label: Macrodactyly\ndefinition : Significant increase in the length and girth of most or all of a digit compared to its contralateral digit (if unaffected) or compared to what would be expected for age/body build. The increased girth is accompanied by an increase in the dorso-ventral dimension AND the lateral dimension of the digit.\nsynonyms :Finger overgrowth; Megalodactyly\n'}


{'id': 'HP_0004100', 'url': 'http://purl.obolibrary.org/obo/HP_0004100', 'lbl': 'Abnormal 2nd finger morphology', 'desc': 'label: Abnormal 2nd finger morphology\ndefinition : An anomaly of the second finger, also known as the index finger.\nsynonyms :Abnormality of index finger; Abnormality of the 2nd finger\n'}


{'id': 'HP_0004110', 'url': 'http://purl.obolibrary.org/obo/HP_0004110', 'lbl': 'obsolete Radially deviated index finger phalanges', 'desc': 'label: obsolete Radially deviated index finger phalanges\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004112', 'url': 'http://purl.obolibrary.org/obo/HP_0004112', 'lbl': 'Midline nasal groove', 'desc': 'label: Midline nasal groove\ndefinition : An abnormal groove on the midline of the nose that may extend to the nasal tip.\nsynonyms :Central nasal groove; Midline nasal groove\n'}


{'id': 'HP_0004121', 'url': 'http://purl.obolibrary.org/obo/HP_0004121', 'lbl': 'obsolete Radially displaced proximal index finger phalanx', 'desc': 'label: obsolete Radially displaced proximal index finger phalanx\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004122', 'url': 'http://purl.obolibrary.org/obo/HP_0004122', 'lbl': 'Midline defect of the nose', 'desc': 'label: Midline defect of the nose\ndefinition : This term groups together three conditions that presumably represent different degrees of severity of a midline defect of the nose or nasal tip.\nsynonyms :Central defect of nose; Central nasal defect; Midline defect of the nose; Midline nasal defect; Central cleft of nose; Midline cleft of nose\n'}


{'id': 'HP_0004132', 'url': 'http://purl.obolibrary.org/obo/HP_0004132', 'lbl': 'Dimple on nasal tip', 'desc': 'label: Dimple on nasal tip\ndefinition : An abnormal indentation of the skin in the region of the nasal tip.\nsynonyms :Dimple on nasal tip; Dimpled tip of nose\n'}


{'id': 'HP_0004138', 'url': 'http://purl.obolibrary.org/obo/HP_0004138', 'lbl': 'obsolete Metaphyseal abnormality of middle phalanx of the 2nd finger', 'desc': 'label: obsolete Metaphyseal abnormality of middle phalanx of the 2nd finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004139', 'url': 'http://purl.obolibrary.org/obo/HP_0004139', 'lbl': 'obsolete Flared metaphysis of middle phalanx of index finger', 'desc': 'label: obsolete Flared metaphysis of middle phalanx of index finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004143', 'url': 'http://purl.obolibrary.org/obo/HP_0004143', 'lbl': 'obsolete Radially deviated terminal index finger phalanx', 'desc': 'label: obsolete Radially deviated terminal index finger phalanx\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004144', 'url': 'http://purl.obolibrary.org/obo/HP_0004144', 'lbl': 'obsolete Duplication of terminal index finger phalanx', 'desc': 'label: obsolete Duplication of terminal index finger phalanx\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004150', 'url': 'http://purl.obolibrary.org/obo/HP_0004150', 'lbl': 'Abnormal 3rd finger morphology', 'desc': 'label: Abnormal 3rd finger morphology\ndefinition : An anomaly of the third finger.\nsynonyms :Abnormality of the 3rd finger; Abnormality of the middle finger\n'}


{'id': 'HP_0004153', 'url': 'http://purl.obolibrary.org/obo/HP_0004153', 'lbl': 'obsolete Overgrowth of middle finger', 'desc': 'label: obsolete Overgrowth of middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004157', 'url': 'http://purl.obolibrary.org/obo/HP_0004157', 'lbl': 'obsolete Accessory middle-finger phalanges', 'desc': 'label: obsolete Accessory middle-finger phalanges\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004161', 'url': 'http://purl.obolibrary.org/obo/HP_0004161', 'lbl': 'obsolete Periosteal new bone of middle finger phalanges', 'desc': 'label: obsolete Periosteal new bone of middle finger phalanges\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004162', 'url': 'http://purl.obolibrary.org/obo/HP_0004162', 'lbl': 'obsolete Radially pointed middle finger phalanges', 'desc': 'label: obsolete Radially pointed middle finger phalanges\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004168', 'url': 'http://purl.obolibrary.org/obo/HP_0004168', 'lbl': 'obsolete Radially pointed proximal middle-finger phalanx', 'desc': 'label: obsolete Radially pointed proximal middle-finger phalanx\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004172', 'url': 'http://purl.obolibrary.org/obo/HP_0004172', 'lbl': 'Abnormality of the middle phalanx of the 3rd finger', 'desc': 'label: Abnormality of the middle phalanx of the 3rd finger\ndefinition : \nsynonyms :Abnormal middle finger bone of the middle finger\n'}


{'id': 'HP_0004174', 'url': 'http://purl.obolibrary.org/obo/HP_0004174', 'lbl': 'obsolete Accessory middle phalanx of middle finger', 'desc': 'label: obsolete Accessory middle phalanx of middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004175', 'url': 'http://purl.obolibrary.org/obo/HP_0004175', 'lbl': 'obsolete Periosteal new bone of middle phalanx of middle-finger', 'desc': 'label: obsolete Periosteal new bone of middle phalanx of middle-finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004180', 'url': 'http://purl.obolibrary.org/obo/HP_0004180', 'lbl': 'Short distal phalanx of the 3rd finger', 'desc': 'label: Short distal phalanx of the 3rd finger\ndefinition : Hypoplasia (congenital reduction in size) of the distal phalanx of the third finger.\nsynonyms :Hypoplastic/small distal phalanx of the 3rd finger; Short distal phalanx of the third finger; Short outermost bone of the middle finger; Short terminal phalanx of middle finger\n'}


{'id': 'HP_0004183', 'url': 'http://purl.obolibrary.org/obo/HP_0004183', 'lbl': 'obsolete Abnormality of the epiphyses of the terminal phalanx of the middle finger', 'desc': 'label: obsolete Abnormality of the epiphyses of the terminal phalanx of the middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004184', 'url': 'http://purl.obolibrary.org/obo/HP_0004184', 'lbl': 'obsolete Cone-shaped epiphysis of terminal phalanx of the middle finger', 'desc': 'label: obsolete Cone-shaped epiphysis of terminal phalanx of the middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004185', 'url': 'http://purl.obolibrary.org/obo/HP_0004185', 'lbl': 'obsolete Fused epiphysis of terminal phalanx of the middle finger', 'desc': 'label: obsolete Fused epiphysis of terminal phalanx of the middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004186', 'url': 'http://purl.obolibrary.org/obo/HP_0004186', 'lbl': 'obsolete Large epiphysis of terminal phalanx of the middle finger', 'desc': 'label: obsolete Large epiphysis of terminal phalanx of the middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004187', 'url': 'http://purl.obolibrary.org/obo/HP_0004187', 'lbl': 'obsolete Prematurely fused epiphysis of terminal phalanx of the middle finger', 'desc': 'label: obsolete Prematurely fused epiphysis of terminal phalanx of the middle finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004188', 'url': 'http://purl.obolibrary.org/obo/HP_0004188', 'lbl': 'Abnormal 4th finger morphology', 'desc': 'label: Abnormal 4th finger morphology\ndefinition : \nsynonyms :Abnormality of the 4th finger; Abnormality of the ring finger\n'}


{'id': 'HP_0004192', 'url': 'http://purl.obolibrary.org/obo/HP_0004192', 'lbl': 'obsolete Bracket epiphyses of the 4th finger', 'desc': 'label: obsolete Bracket epiphyses of the 4th finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004193', 'url': 'http://purl.obolibrary.org/obo/HP_0004193', 'lbl': 'obsolete Expanded phalanges of the ring finger', 'desc': 'label: obsolete Expanded phalanges of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004194', 'url': 'http://purl.obolibrary.org/obo/HP_0004194', 'lbl': 'obsolete Hypoplastic phalanges of the ring finger', 'desc': 'label: obsolete Hypoplastic phalanges of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004195', 'url': 'http://purl.obolibrary.org/obo/HP_0004195', 'lbl': 'Osteolytic defects of the phalanges of the 4th finger', 'desc': 'label: Osteolytic defects of the phalanges of the 4th finger\ndefinition : Osteolytic defects of the phalanges of the 4th (ring) finger.\nsynonyms :Lytic defects of the phalanges of the ring finger\n'}


{'id': 'HP_0004196', 'url': 'http://purl.obolibrary.org/obo/HP_0004196', 'lbl': 'obsolete Short phalanges of the ring finger', 'desc': 'label: obsolete Short phalanges of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004197', 'url': 'http://purl.obolibrary.org/obo/HP_0004197', 'lbl': 'Symphalangism of the 4th finger', 'desc': 'label: Symphalangism of the 4th finger\ndefinition : Fusion of two or more bones of the 4th finger.\nsynonyms :Fused ring finger bones; Symphalangism of the ring finger\n'}


{'id': 'HP_0004198', 'url': 'http://purl.obolibrary.org/obo/HP_0004198', 'lbl': 'obsolete Wide/broad phalanges of the ring finger', 'desc': 'label: obsolete Wide/broad phalanges of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004201', 'url': 'http://purl.obolibrary.org/obo/HP_0004201', 'lbl': 'obsolete Expanded proximal phalanx of the ring finger', 'desc': 'label: obsolete Expanded proximal phalanx of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004202', 'url': 'http://purl.obolibrary.org/obo/HP_0004202', 'lbl': 'obsolete Lytic defects of the proximal phalanx of the ring finger', 'desc': 'label: obsolete Lytic defects of the proximal phalanx of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004203', 'url': 'http://purl.obolibrary.org/obo/HP_0004203', 'lbl': 'obsolete Short proximal phalanx of the ring finger', 'desc': 'label: obsolete Short proximal phalanx of the ring finger\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004207', 'url': 'http://purl.obolibrary.org/obo/HP_0004207', 'lbl': 'Abnormal 5th finger morphology', 'desc': 'label: Abnormal 5th finger morphology\ndefinition : An abnormality affecting one or both 5th fingers.\nsynonyms :Abnormality of the 5th finger; Abnormality of the little finger; Abnormality of the pinkie finger; Abnormality of the pinky finger\n'}


{'id': 'HP_0004209', 'url': 'http://purl.obolibrary.org/obo/HP_0004209', 'lbl': 'Clinodactyly of the 5th finger', 'desc': 'label: Clinodactyly of the 5th finger\ndefinition : Clinodactyly refers to a bending or curvature of the fifth finger in the radial direction (i.e., towards the 4th finger).\nsynonyms :Curvature of little finger; Curvature of pinkie finger; Curvature of pinky finger; Bilateral fifth digit clinodactyly; Bilateral fifth finger clinodactyly; Clinodactyly of fifth digit; Clinodactyly of the little finger; Fifth finger clinodactyly; Permanent curving of the pinkie finger\n'}


{'id': 'HP_0004213', 'url': 'http://purl.obolibrary.org/obo/HP_0004213', 'lbl': 'Abnormal 5th finger phalanx morphology', 'desc': 'label: Abnormal 5th finger phalanx morphology\ndefinition : Abnormality of the phalanges of the 5th (little) finger.\nsynonyms :Abnormality of the little finger bone; Abnormality of the phalanges of the 5th finger; Abnormality of the pinkie finger bone; Abnormality of the pinky finger bone\n'}


{'id': 'HP_0004214', 'url': 'http://purl.obolibrary.org/obo/HP_0004214', 'lbl': 'Curved phalanges of the 5th finger', 'desc': 'label: Curved phalanges of the 5th finger\ndefinition : Curved phalanges of the 5th (little) finger.\nsynonyms :Curved little finger bone; Curved pinkie finger bone; Curved pinky finger bone\n'}


{'id': 'HP_0004216', 'url': 'http://purl.obolibrary.org/obo/HP_0004216', 'lbl': 'Osteolytic defects of the phalanges of the 5th finger', 'desc': 'label: Osteolytic defects of the phalanges of the 5th finger\ndefinition : Dissolution or degeneration of bone tissue of the phalanges of the 5th finger.\nsynonyms :Lytic defects of the phalanges of the little finger\n'}


{'id': 'HP_0004218', 'url': 'http://purl.obolibrary.org/obo/HP_0004218', 'lbl': 'Symphalangism of the 5th finger', 'desc': 'label: Symphalangism of the 5th finger\ndefinition : Fusion of two or more bones of the 5th finger.\nsynonyms :Fifth finger symphalangism; Fused little finger bones; Fused pinkie finger bones; Fused pinky finger bones; Symphalagism of the little finger\n'}


{'id': 'HP_0004219', 'url': 'http://purl.obolibrary.org/obo/HP_0004219', 'lbl': 'Abnormality of the middle phalanx of the 5th finger', 'desc': 'label: Abnormality of the middle phalanx of the 5th finger\ndefinition : \nsynonyms :Abnormality of the middle bone of little finger; Abnormality of the middle bone of pinkie finger; Abnormality of the middle bone of pinky finger\n'}


{'id': 'HP_0004220', 'url': 'http://purl.obolibrary.org/obo/HP_0004220', 'lbl': 'Short middle phalanx of the 5th finger', 'desc': 'label: Short middle phalanx of the 5th finger\ndefinition : Hypoplastic/small middle phalanx of the fifth finger.\nsynonyms :5th finger middle phalangeal hypoplasia; Brachymesophalangism V; Brachymesophalangy V (finger); Fifth finger mid-phalanx hypoplasia; Hypoplastic fifth finger middle phalanx; Hypoplastic middle phalanx of the 5th finger; Hypoplastic/small middle phalanx of the 5th finger; Hypoplastic/small middle phalanx of the little finger; Short middle bone of the little finger; Short middle bone of the pinkie finger; Short middle bone of the pinky finger; Short middle phalanx of the little finger; Type A3 brachydactyly\n'}


{'id': 'HP_0004222', 'url': 'http://purl.obolibrary.org/obo/HP_0004222', 'lbl': 'Cone-shaped epiphysis of the distal phalanx of the 5th finger', 'desc': "label: Cone-shaped epiphysis of the distal phalanx of the 5th finger\ndefinition : A cone-shaped appearance of the epiphysis of the distal phalanx of the little finger of the hand, producing a 'ball-in-a-socket' appearance. This epiphysis is located at the proximal end of the phalanx and is normally nearly flat. The related entity 'angel-shaped' epiphysis refers to a pronounced cone-shaped epiphysis in combination with a pseudoepiphysis at the distal end of the phalanx.\nsynonyms :Cone-shaped end part of the outermost little finger bone; Cone-shaped end part of the outermost pinkie finger bone; Cone-shaped end part of the outermost pinky finger bone; Cone-shaped epiphysis of the distal phalanx of the little finger\n"}


{'id': 'HP_0004223', 'url': 'http://purl.obolibrary.org/obo/HP_0004223', 'lbl': 'Ivory epiphysis of the distal phalanx of the 5th finger', 'desc': 'label: Ivory epiphysis of the distal phalanx of the 5th finger\ndefinition : Sclerosis of the epiphysis of the distal phalanx of the little finger, leading to an increased degree of radiopacity (white or ivory appearance) in X-rays.\nsynonyms :Increased bone density of end part of the outermost little finger bone; Increased bone density of end part of the outermost pinkie finger bone; Increased bone density of end part of the outermost pinky finger bone; Ivory epiphysis of the distal phalanx of the little finger; Ivory epiphysis of the terminal phalanx of the little finger\n'}


{'id': 'HP_0004224', 'url': 'http://purl.obolibrary.org/obo/HP_0004224', 'lbl': 'Abnormality of the epiphysis of the middle phalanx of the 5th finger', 'desc': 'label: Abnormality of the epiphysis of the middle phalanx of the 5th finger\ndefinition : Abnormality of the epiphysis of the middle phalanx of the fifth finger. This epiphysis is located on the proximal end of the phalanx.\nsynonyms :Abnormality of the end part of middle little finger bone; Abnormality of the end part of middle pinkie finger bone; Abnormality of the end part of middle pinky finger bone\n'}


{'id': 'HP_0004225', 'url': 'http://purl.obolibrary.org/obo/HP_0004225', 'lbl': 'Abnormality of the distal phalanx of the 5th finger', 'desc': 'label: Abnormality of the distal phalanx of the 5th finger\ndefinition : Abnormality of the distal phalanx of the 5th (little) finger.\nsynonyms :Abnormality of the distal phalanx of the little finger; Abnormality of the outermost little finger bone; Abnormality of the outermost pinkie finger bone; Abnormality of the outermost pinky finger bone; Abnormality of the terminal phalanx of the little finger\n'}


{'id': 'HP_0004226', 'url': 'http://purl.obolibrary.org/obo/HP_0004226', 'lbl': 'Curved distal phalanx of the 5th finger', 'desc': 'label: Curved distal phalanx of the 5th finger\ndefinition : Curved appearance of the distal phalanx of the 5th (little) finger.\nsynonyms :Curved outermost little finger bone; Curved outermost pinkie finger bone; Curved outermost pinky finger bone; Curved terminal phalanx of the little finger\n'}


{'id': 'HP_0004227', 'url': 'http://purl.obolibrary.org/obo/HP_0004227', 'lbl': 'Short distal phalanx of the 5th finger', 'desc': 'label: Short distal phalanx of the 5th finger\ndefinition : Hypoplastic/small distal phalanx of the fifth finger.\nsynonyms :Brachytelophalangism V; Fifth digit distal phalangeal hypoplasia; Hypoplastic/small terminal phalanx of the little finger; Short distal phalanx of the fifth finger; Short outermost little finger bone; Short outermost pinkie finger bone; Short outermost pinky finger bone\n'}


{'id': 'HP_0004230', 'url': 'http://purl.obolibrary.org/obo/HP_0004230', 'lbl': 'Subluxation of the proximal interphalangeal joint of the little finger', 'desc': 'label: Subluxation of the proximal interphalangeal joint of the little finger\ndefinition : A partial dislocation of the proximal interphalangeal joint of the little finger.\nsynonyms :Partially dislocated innermost hinge joint of little finger; Partially dislocated innermost hinge joint of pinkie finger; Partially dislocated innermost hinge joint of pinky finger\n'}


{'id': 'HP_0004231', 'url': 'http://purl.obolibrary.org/obo/HP_0004231', 'lbl': 'Carpal bone aplasia', 'desc': 'label: Carpal bone aplasia\ndefinition : Congenital absence of a carpal bone.\nsynonyms :Absent wrist bone; Missing wrist bone; Absent carpal bone; Absent carpal bones; Absent carpal ossification center; Absent carpal ossification centre; Aplastic carpal bone\n'}


{'id': 'HP_0004232', 'url': 'http://purl.obolibrary.org/obo/HP_0004232', 'lbl': 'Accessory carpal bones', 'desc': 'label: Accessory carpal bones\ndefinition : The presence of more than the normal number of carpal bones.\nsynonyms :Extra wrist bones; Supernumerary carpal bones\n'}


{'id': 'HP_0004233', 'url': 'http://purl.obolibrary.org/obo/HP_0004233', 'lbl': 'Advanced ossification of carpal bones', 'desc': 'label: Advanced ossification of carpal bones\ndefinition : Ossification of carpal bones at an abnormally early age.\nsynonyms :Accelerated wrist bone maturation; Accelerated carpal bone maturation; Advanced carpal bone age; Advanced carpal ossification; Precociously ossified carpal bones\n'}


{'id': 'HP_0004234', 'url': 'http://purl.obolibrary.org/obo/HP_0004234', 'lbl': 'Bone-in-a-bone appearance of carpal bones', 'desc': 'label: Bone-in-a-bone appearance of carpal bones\ndefinition : The bone-in-bone sign is a radiographic finding produced by increased sclerosis (abnormally dense bone) occurring intermittently with zones of relatively normal bone density. This term should be used to describe such a finding in the carpal bones.\nsynonyms :Bone-in-a-bone appearance of wrist bones\n'}


{'id': 'HP_0004235', 'url': 'http://purl.obolibrary.org/obo/HP_0004235', 'lbl': 'Comma-shaped carpal bones', 'desc': 'label: Comma-shaped carpal bones\ndefinition : \nsynonyms :Comma-shaped wrist bones\n'}


{'id': 'HP_0004236', 'url': 'http://purl.obolibrary.org/obo/HP_0004236', 'lbl': 'Irregular carpal bones', 'desc': 'label: Irregular carpal bones\ndefinition : Carpal bones with irregular or fragmented margins.\nsynonyms :Irregular wrist bones\n'}


{'id': 'HP_0004237', 'url': 'http://purl.obolibrary.org/obo/HP_0004237', 'lbl': 'Large carpal bones', 'desc': 'label: Large carpal bones\ndefinition : Increased size of carpal bones.\nsynonyms :Large wrist bones; Large carpals\n'}


{'id': 'HP_0004238', 'url': 'http://purl.obolibrary.org/obo/HP_0004238', 'lbl': 'Lytic defects of carpal bones', 'desc': 'label: Lytic defects of carpal bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004239', 'url': 'http://purl.obolibrary.org/obo/HP_0004239', 'lbl': 'Proximally placed carpal bones', 'desc': 'label: Proximally placed carpal bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004240', 'url': 'http://purl.obolibrary.org/obo/HP_0004240', 'lbl': 'Sclerotic foci within carpal bones', 'desc': 'label: Sclerotic foci within carpal bones\ndefinition : \nsynonyms :Hardened spots within wrist bones; Stiffened spots within wrist bones\n'}


{'id': 'HP_0004241', 'url': 'http://purl.obolibrary.org/obo/HP_0004241', 'lbl': 'Stippled calcification in carpal bones', 'desc': 'label: Stippled calcification in carpal bones\ndefinition : Point-shaped (punctate) calcifications affecting the carpal bones.\nsynonyms :Punctate calcifications of carpals\n'}


{'id': 'HP_0004242', 'url': 'http://purl.obolibrary.org/obo/HP_0004242', 'lbl': 'Broad carpal bones', 'desc': 'label: Broad carpal bones\ndefinition : \nsynonyms :Wide wrist bones; Wide carpal bones\n'}


{'id': 'HP_0004243', 'url': 'http://purl.obolibrary.org/obo/HP_0004243', 'lbl': 'Abnormality of the scaphoid', 'desc': 'label: Abnormality of the scaphoid\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004244', 'url': 'http://purl.obolibrary.org/obo/HP_0004244', 'lbl': 'Accessory scaphoid', 'desc': 'label: Accessory scaphoid\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004245', 'url': 'http://purl.obolibrary.org/obo/HP_0004245', 'lbl': 'Comma-shaped scaphoid', 'desc': 'label: Comma-shaped scaphoid\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004246', 'url': 'http://purl.obolibrary.org/obo/HP_0004246', 'lbl': 'Delayed ossification of the scaphoid', 'desc': 'label: Delayed ossification of the scaphoid\ndefinition : Formation of bone tissue of scaphoid is less than expected for age.\nsynonyms :Delayed maturation of the scaphoid\n'}


{'id': 'HP_0004247', 'url': 'http://purl.obolibrary.org/obo/HP_0004247', 'lbl': 'Small scaphoid', 'desc': 'label: Small scaphoid\ndefinition : Underdevelopment of the scaphoid.\nsynonyms :\n'}


{'id': 'HP_0004248', 'url': 'http://purl.obolibrary.org/obo/HP_0004248', 'lbl': 'Abnormality of the lunate bone', 'desc': 'label: Abnormality of the lunate bone\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004249', 'url': 'http://purl.obolibrary.org/obo/HP_0004249', 'lbl': 'Accessory lunate', 'desc': 'label: Accessory lunate\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004250', 'url': 'http://purl.obolibrary.org/obo/HP_0004250', 'lbl': 'Proximally placed lunate', 'desc': 'label: Proximally placed lunate\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004251', 'url': 'http://purl.obolibrary.org/obo/HP_0004251', 'lbl': 'Lunate-triquetral fusion', 'desc': 'label: Lunate-triquetral fusion\ndefinition : Osseous fusion of the lunate and triquetrum.\nsynonyms :Lunotriquetral synostosis\n'}


{'id': 'HP_0004252', 'url': 'http://purl.obolibrary.org/obo/HP_0004252', 'lbl': 'Abnormality of the trapezium', 'desc': 'label: Abnormality of the trapezium\ndefinition : An anomaly of trapezium.\nsynonyms :\n'}


{'id': 'HP_0004253', 'url': 'http://purl.obolibrary.org/obo/HP_0004253', 'lbl': 'Absent trapezium', 'desc': 'label: Absent trapezium\ndefinition : \nsynonyms :Absent trapezium bone\n'}


{'id': 'HP_0004254', 'url': 'http://purl.obolibrary.org/obo/HP_0004254', 'lbl': 'Delayed ossification of the trapezium', 'desc': 'label: Delayed ossification of the trapezium\ndefinition : Formation of bone tissue of trapezium is less than expected for age.\nsynonyms :Delayed maturation of the trapezium\n'}


{'id': 'HP_0004255', 'url': 'http://purl.obolibrary.org/obo/HP_0004255', 'lbl': 'Small trapezium', 'desc': 'label: Small trapezium\ndefinition : Underdevelopment of the trapezium.\nsynonyms :\n'}


{'id': 'HP_0004256', 'url': 'http://purl.obolibrary.org/obo/HP_0004256', 'lbl': 'Abnormality of the trapezoid bone', 'desc': 'label: Abnormality of the trapezoid bone\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004257', 'url': 'http://purl.obolibrary.org/obo/HP_0004257', 'lbl': 'Delayed ossification of the trapezoid bone', 'desc': 'label: Delayed ossification of the trapezoid bone\ndefinition : Formation of bone tissue of trapezoid is less than expected for age.\nsynonyms :Delayed maturation of the trapezoid bone\n'}


{'id': 'HP_0004258', 'url': 'http://purl.obolibrary.org/obo/HP_0004258', 'lbl': 'Small trapezoid bone', 'desc': 'label: Small trapezoid bone\ndefinition : Underdevelopment of the trapezoid.\nsynonyms :\n'}


{'id': 'HP_0004259', 'url': 'http://purl.obolibrary.org/obo/HP_0004259', 'lbl': 'Abnormality of the hamate bone', 'desc': 'label: Abnormality of the hamate bone\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004260', 'url': 'http://purl.obolibrary.org/obo/HP_0004260', 'lbl': 'Large hamate bone', 'desc': 'label: Large hamate bone\ndefinition : \nsynonyms :Large unciform bone\n'}


{'id': 'HP_0004261', 'url': 'http://purl.obolibrary.org/obo/HP_0004261', 'lbl': 'Wide hamate bone', 'desc': 'label: Wide hamate bone\ndefinition : \nsynonyms :Broad hamate bone; Wide unciform bone\n'}


{'id': 'HP_0004262', 'url': 'http://purl.obolibrary.org/obo/HP_0004262', 'lbl': 'Abnormality of the capitate bone', 'desc': 'label: Abnormality of the capitate bone\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004263', 'url': 'http://purl.obolibrary.org/obo/HP_0004263', 'lbl': 'Large capitate bone', 'desc': 'label: Large capitate bone\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004264', 'url': 'http://purl.obolibrary.org/obo/HP_0004264', 'lbl': 'Narrow carpal joint spaces', 'desc': 'label: Narrow carpal joint spaces\ndefinition : \nsynonyms :Decreased carpal joint angles\n'}


{'id': 'HP_0004267', 'url': 'http://purl.obolibrary.org/obo/HP_0004267', 'lbl': 'Narrow small joints of the hand', 'desc': 'label: Narrow small joints of the hand\ndefinition : \nsynonyms :Narrow small joints of the hand\n'}


{'id': 'HP_0004268', 'url': 'http://purl.obolibrary.org/obo/HP_0004268', 'lbl': 'Osteoarthritis of the small joints of the hand', 'desc': 'label: Osteoarthritis of the small joints of the hand\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004269', 'url': 'http://purl.obolibrary.org/obo/HP_0004269', 'lbl': 'Subluxation of the small joints of the hand', 'desc': 'label: Subluxation of the small joints of the hand\ndefinition : A partial dislocation of some or all of the small joints of the hand.\nsynonyms :Partial dislocation of small joints of hand\n'}


{'id': 'HP_0004271', 'url': 'http://purl.obolibrary.org/obo/HP_0004271', 'lbl': 'Cortical thickening of hand bones', 'desc': 'label: Cortical thickening of hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004272', 'url': 'http://purl.obolibrary.org/obo/HP_0004272', 'lbl': 'Cortical thinning of hand bones', 'desc': 'label: Cortical thinning of hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004273', 'url': 'http://purl.obolibrary.org/obo/HP_0004273', 'lbl': 'Cupped metaphyses of hand bones', 'desc': 'label: Cupped metaphyses of hand bones\ndefinition : \nsynonyms :Cupped metaphysis of hand bones; Cupped wide portion of hand bones\n'}


{'id': 'HP_0004274', 'url': 'http://purl.obolibrary.org/obo/HP_0004274', 'lbl': 'Deficient ossification of hand bones', 'desc': 'label: Deficient ossification of hand bones\ndefinition : \nsynonyms :Deficient maturation of hand bones\n'}


{'id': 'HP_0004275', 'url': 'http://purl.obolibrary.org/obo/HP_0004275', 'lbl': 'Duplication of hand bones', 'desc': 'label: Duplication of hand bones\ndefinition : \nsynonyms :Duplication of hand bones\n'}


{'id': 'HP_0004276', 'url': 'http://purl.obolibrary.org/obo/HP_0004276', 'lbl': 'Exostoses of hand bones', 'desc': 'label: Exostoses of hand bones\ndefinition : Abnormal formation of new bone on the surface of a bone of the hand.\nsynonyms :\n'}


{'id': 'HP_0004277', 'url': 'http://purl.obolibrary.org/obo/HP_0004277', 'lbl': 'Fractured hand bones', 'desc': 'label: Fractured hand bones\ndefinition : \nsynonyms :Broken hand bones; Fractured hand bones\n'}


{'id': 'HP_0004278', 'url': 'http://purl.obolibrary.org/obo/HP_0004278', 'lbl': 'Synostosis involving bones of the hand', 'desc': 'label: Synostosis involving bones of the hand\ndefinition : An abnormal union between bones or parts of bones of the hand.\nsynonyms :Fused hand bones\n'}


{'id': 'HP_0004279', 'url': 'http://purl.obolibrary.org/obo/HP_0004279', 'lbl': 'Short palm', 'desc': 'label: Short palm\ndefinition : Short palm.\nsynonyms :Short palm; Hypoplastic hands; Short hands; Short palms\n'}


{'id': 'HP_0004280', 'url': 'http://purl.obolibrary.org/obo/HP_0004280', 'lbl': 'Irregular ossification of hand bones', 'desc': 'label: Irregular ossification of hand bones\ndefinition : \nsynonyms :Irregular maturation of hand bones\n'}


{'id': 'HP_0004281', 'url': 'http://purl.obolibrary.org/obo/HP_0004281', 'lbl': 'Irregular sclerosis of hand bones', 'desc': 'label: Irregular sclerosis of hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004283', 'url': 'http://purl.obolibrary.org/obo/HP_0004283', 'lbl': 'Narrow palm', 'desc': 'label: Narrow palm\ndefinition : For children from birth to 4 years of age, the palm width is more than 2 SD below the mean; for children from 4 to 16 years of age the palm width is below the 5th centile; or, the width of the palm appears disproportionately narrow for its length.\nsynonyms :Narrow hand; Narrow palm; Narrow hands\n'}


{'id': 'HP_0004284', 'url': 'http://purl.obolibrary.org/obo/HP_0004284', 'lbl': 'Notched hand bones', 'desc': 'label: Notched hand bones\ndefinition : \nsynonyms :Notched hand bones\n'}


{'id': 'HP_0004285', 'url': 'http://purl.obolibrary.org/obo/HP_0004285', 'lbl': 'Overmodelled hand bones', 'desc': 'label: Overmodelled hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004286', 'url': 'http://purl.obolibrary.org/obo/HP_0004286', 'lbl': 'Patchy sclerosis of hand bones', 'desc': 'label: Patchy sclerosis of hand bones\ndefinition : \nsynonyms :Uneven increase in bone density in hand bones\n'}


{'id': 'HP_0004287', 'url': 'http://purl.obolibrary.org/obo/HP_0004287', 'lbl': 'Pointed hand bones', 'desc': 'label: Pointed hand bones\ndefinition : \nsynonyms :Pointed hand bones\n'}


{'id': 'HP_0004288', 'url': 'http://purl.obolibrary.org/obo/HP_0004288', 'lbl': 'Pseudoepiphyses of hand bones', 'desc': 'label: Pseudoepiphyses of hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004289', 'url': 'http://purl.obolibrary.org/obo/HP_0004289', 'lbl': 'Sclerotic foci in hand bones', 'desc': 'label: Sclerotic foci in hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004290', 'url': 'http://purl.obolibrary.org/obo/HP_0004290', 'lbl': 'Sclerosis of hand bones with transverse striations', 'desc': 'label: Sclerosis of hand bones with transverse striations\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004291', 'url': 'http://purl.obolibrary.org/obo/HP_0004291', 'lbl': 'Stippled calcification of hand bones', 'desc': 'label: Stippled calcification of hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004292', 'url': 'http://purl.obolibrary.org/obo/HP_0004292', 'lbl': 'Undermodelled hand bones', 'desc': 'label: Undermodelled hand bones\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004293', 'url': 'http://purl.obolibrary.org/obo/HP_0004293', 'lbl': 'Synostosis of second metacarpal-trapezoid', 'desc': 'label: Synostosis of second metacarpal-trapezoid\ndefinition : Fusion of the second metacarpal-trapezoid.\nsynonyms :Fusion of second metacarpal-trapezoid\n'}


{'id': 'HP_0004294', 'url': 'http://purl.obolibrary.org/obo/HP_0004294', 'lbl': 'Subluxation of metacarpal phalangeal joints', 'desc': 'label: Subluxation of metacarpal phalangeal joints\ndefinition : A partial dislocation affecting some or all of the metacarpophalangeal joints.\nsynonyms :Partial knuckle dislocation; Subluxation of metacarpophalangeal joints\n'}


{'id': 'HP_0004295', 'url': 'http://purl.obolibrary.org/obo/HP_0004295', 'lbl': 'Abnormal gastric mucosa morphology', 'desc': 'label: Abnormal gastric mucosa morphology\ndefinition : An abnormality of the gastric mucous membrane.\nsynonyms :Abnormality of the gastric mucosa; Abnormality of the mucous membrane layer of stomach\n'}


{'id': 'HP_0004296', 'url': 'http://purl.obolibrary.org/obo/HP_0004296', 'lbl': 'Abnormal gastrointestinal vascular morphology', 'desc': 'label: Abnormal gastrointestinal vascular morphology\ndefinition : \nsynonyms :Abnormality of GI blood vessels; Abnormality of GI vasculature; Abnormality of gastrointestinal vasculature\n'}


{'id': 'HP_0004297', 'url': 'http://purl.obolibrary.org/obo/HP_0004297', 'lbl': 'Abnormality of the biliary system', 'desc': 'label: Abnormality of the biliary system\ndefinition : An abnormality of the biliary system.\nsynonyms :\n'}


{'id': 'HP_0004298', 'url': 'http://purl.obolibrary.org/obo/HP_0004298', 'lbl': 'Abnormality of the abdominal wall', 'desc': 'label: Abnormality of the abdominal wall\ndefinition : The presence of any abnormality affecting the abdominal wall.\nsynonyms :Abnormality of external features of the abdomen; Abnormality of the abdominal wall\n'}


{'id': 'HP_0004299', 'url': 'http://purl.obolibrary.org/obo/HP_0004299', 'lbl': 'Hernia of the abdominal wall', 'desc': 'label: Hernia of the abdominal wall\ndefinition : The presence of a hernia in the abdominal wall.\nsynonyms :Herniated abdominal wall\n'}


{'id': 'HP_0004302', 'url': 'http://purl.obolibrary.org/obo/HP_0004302', 'lbl': 'Functional motor deficit', 'desc': 'label: Functional motor deficit\ndefinition : \nsynonyms :Functional motor problems\n'}


{'id': 'HP_0004303', 'url': 'http://purl.obolibrary.org/obo/HP_0004303', 'lbl': 'Abnormal muscle fiber morphology', 'desc': 'label: Abnormal muscle fiber morphology\ndefinition : Any abnormality of the skeletal muscle cell. Muscle fibers are subdivided into two types. Type I fibers are fatigue-resistant and rich in oxidative enzymes (they stain light with the myosin ATPase reaction), and type II fibers are fast-contracting, fatigue-prone, and rich in glycolytic enzymes (these fibers stain darkly). Normal muscle tissue has a random distribution of type I and type II fibers.\nsynonyms :Abnormal muscle fibre morphology; Abnormal skeletal muscle fiber morphology; Abnormal skeletal muscle fibre morphology; Abnormality of muscle fibers; Abnormality of muscle fibres\n'}


{'id': 'HP_0004305', 'url': 'http://purl.obolibrary.org/obo/HP_0004305', 'lbl': 'Involuntary movements', 'desc': 'label: Involuntary movements\ndefinition : Involuntary contractions of muscle leading to involuntary movements of extremities, neck, trunk, or face.\nsynonyms :Involuntary movements; Involuntary muscle contractions\n'}


{'id': 'HP_0004306', 'url': 'http://purl.obolibrary.org/obo/HP_0004306', 'lbl': 'Abnormal endocardium morphology', 'desc': 'label: Abnormal endocardium morphology\ndefinition : An abnormality of the endocardium.\nsynonyms :Abnormality of the endocardium; Abnormality of the endomycoardium\n'}


{'id': 'HP_0004307', 'url': 'http://purl.obolibrary.org/obo/HP_0004307', 'lbl': 'Abnormal anatomic location of the heart', 'desc': 'label: Abnormal anatomic location of the heart\ndefinition : Developmental defect characterized by an anomalous anatomic location of the heart.\nsynonyms :\n'}


{'id': 'HP_0004308', 'url': 'http://purl.obolibrary.org/obo/HP_0004308', 'lbl': 'Ventricular arrhythmia', 'desc': 'label: Ventricular arrhythmia\ndefinition : \nsynonyms :Ventricular arrhythmias\n'}


{'id': 'HP_0004309', 'url': 'http://purl.obolibrary.org/obo/HP_0004309', 'lbl': 'Ventricular preexcitation', 'desc': 'label: Ventricular preexcitation\ndefinition : An abnormality in which the cardiac ventricles depolarize too early as a result of an abnormality of cardiac conduction pathways such as an accessory pathway.\nsynonyms :Pre-excitation syndrome; Preexcitation; Ventricular pre-excitation\n'}


{'id': 'HP_0004311', 'url': 'http://purl.obolibrary.org/obo/HP_0004311', 'lbl': 'Abnormal macrophage morphology', 'desc': 'label: Abnormal macrophage morphology\ndefinition : An abnormality of macrophages.\nsynonyms :Abnormality of histiocytes; Abnormality of macrophages\n'}


{'id': 'HP_0004312', 'url': 'http://purl.obolibrary.org/obo/HP_0004312', 'lbl': 'Abnormal reticulocyte morphology', 'desc': 'label: Abnormal reticulocyte morphology\ndefinition : A reticulocyte abnormality.\nsynonyms :Abnormality of reticulocytes\n'}


{'id': 'HP_0004313', 'url': 'http://purl.obolibrary.org/obo/HP_0004313', 'lbl': 'Decreased circulating antibody level', 'desc': 'label: Decreased circulating antibody level\ndefinition : An abnormally decreased level of immunoglobulin in blood.\nsynonyms :Decreased antibody level in blood; Decreased immunoglobulin level; Decreased serum immunoglobulin; Hypogammaglobulinemia; Immunoglobulin deficiency; Reduced immunoglobulin levels\n'}


{'id': 'HP_0004315', 'url': 'http://purl.obolibrary.org/obo/HP_0004315', 'lbl': 'Decreased circulating IgG level', 'desc': 'label: Decreased circulating IgG level\ndefinition : An abnormally decreased level of immunoglobulin G (IgG) in blood.\nsynonyms :Decreased IgG level; Decreased IgG level in blood; Decreased gamma-globin expression; Decreased immunoglobulin G; Decreased serum IgG; IgG deficiency; Reduced IgG levels\n'}


{'id': 'HP_0004319', 'url': 'http://purl.obolibrary.org/obo/HP_0004319', 'lbl': 'Decreased circulating aldosterone level', 'desc': 'label: Decreased circulating aldosterone level\ndefinition : Abnormally reduced levels of aldosterone.\nsynonyms :Decreased aldosterone; Decreased aldosterone production; Decreased serum aldosterone; Hypoaldosteronism; Low blood aldosterone level; Mineralocorticoid insufficiency\n'}


{'id': 'HP_0004320', 'url': 'http://purl.obolibrary.org/obo/HP_0004320', 'lbl': 'Vaginal fistula', 'desc': 'label: Vaginal fistula\ndefinition : The presence of a fistula of the vagina.\nsynonyms :\n'}


{'id': 'HP_0004321', 'url': 'http://purl.obolibrary.org/obo/HP_0004321', 'lbl': 'Bladder fistula', 'desc': 'label: Bladder fistula\ndefinition : The presence of a fistula connecting the urinary bladder to another organ or the skin. The fistula can involve the bowel, the vagina, or rarely, the skin.\nsynonyms :\n'}


{'id': 'HP_0004322', 'url': 'http://purl.obolibrary.org/obo/HP_0004322', 'lbl': 'Short stature', 'desc': 'label: Short stature\ndefinition : A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms).\nsynonyms :Decreased body height; Height less than 3rd percentile; Short stature; Small stature; Stature below 3rd percentile\n'}


{'id': 'HP_0004323', 'url': 'http://purl.obolibrary.org/obo/HP_0004323', 'lbl': 'Abnormality of body weight', 'desc': 'label: Abnormality of body weight\ndefinition : An abnormal increase or decrease of weight or an abnormal distribution of mass in the body.\nsynonyms :Abnormality of body weight; Abnormality of habitus\n'}


{'id': 'HP_0004324', 'url': 'http://purl.obolibrary.org/obo/HP_0004324', 'lbl': 'Increased body weight', 'desc': 'label: Increased body weight\ndefinition : Abnormally increased body weight.\nsynonyms :Increased body weight; Weight gain\n'}


{'id': 'HP_0004325', 'url': 'http://purl.obolibrary.org/obo/HP_0004325', 'lbl': 'Decreased body weight', 'desc': 'label: Decreased body weight\ndefinition : Abnormally low body weight.\nsynonyms :Decreased body weight; Decreased weight; Low body weight; Low weight; Weight less than 3rd percentile\n'}


{'id': 'HP_0004326', 'url': 'http://purl.obolibrary.org/obo/HP_0004326', 'lbl': 'Cachexia', 'desc': 'label: Cachexia\ndefinition : Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease.\nsynonyms :Wasting syndrome\n'}


{'id': 'HP_0004327', 'url': 'http://purl.obolibrary.org/obo/HP_0004327', 'lbl': 'Abnormal vitreous humor morphology', 'desc': 'label: Abnormal vitreous humor morphology\ndefinition : Any structural anomaly of the vitreous body.\nsynonyms :Abnormal vitreous humour morphology\n'}


{'id': 'HP_0004328', 'url': 'http://purl.obolibrary.org/obo/HP_0004328', 'lbl': 'Abnormal anterior eye segment morphology', 'desc': 'label: Abnormal anterior eye segment morphology\ndefinition : An abnormality of the anterior segment of the eyeball (which comprises the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens).\nsynonyms :Abnormal anterior segment morphology; Abnormality of the anterior segment of the eye; Abnormality of the anterior segment of the eyeball; Abnormality of the anterior segment of the globe\n'}


{'id': 'HP_0004329', 'url': 'http://purl.obolibrary.org/obo/HP_0004329', 'lbl': 'Abnormal posterior eye segment morphology', 'desc': 'label: Abnormal posterior eye segment morphology\ndefinition : \nsynonyms :Abnormal morphology of the posterior segment of the globe; Abnormality of the posterior segment of the eye; Abnormality of the posterior segment of the eyeball; Abnormality of the posterior segment of the globe\n'}


{'id': 'HP_0004330', 'url': 'http://purl.obolibrary.org/obo/HP_0004330', 'lbl': 'Increased skull ossification', 'desc': 'label: Increased skull ossification\ndefinition : An increase in the magnitude or amount of ossification of the skull.\nsynonyms :Hyperossification of skull; Hyperostosis of skull; Sclerosis of bones of skull; Sclerosis of skull; Increased Mineralization of skull; Increased calcification of skull\n'}


{'id': 'HP_0004331', 'url': 'http://purl.obolibrary.org/obo/HP_0004331', 'lbl': 'Decreased skull ossification', 'desc': 'label: Decreased skull ossification\ndefinition : A reduction in the magnitude or amount of ossification of the skull.\nsynonyms :Decreased bone formation of skull; Deficient skull ossification; Hypoossification of skull; Ossification defect of skull; Poorly mineralized skull; Poorly ossified skull; Poorly ossified skull bones; Decreased calcification of skull; Decreased mineralization of skull\n'}


{'id': 'HP_0004332', 'url': 'http://purl.obolibrary.org/obo/HP_0004332', 'lbl': 'Abnormal lymphocyte morphology', 'desc': 'label: Abnormal lymphocyte morphology\ndefinition : An abnormality of lymphocytes.\nsynonyms :Abnormal lymphocytes; Abnormality of cells of the lymphoid lineage\n'}


{'id': 'HP_0004333', 'url': 'http://purl.obolibrary.org/obo/HP_0004333', 'lbl': 'Bone-marrow foam cells', 'desc': "label: Bone-marrow foam cells\ndefinition : The presence of foam cells in the bone marrow, generally demonstrated by bone-marrow aspiration or biopsy. Foam cells have a vacuolated appearance due to the presence of complex lipid deposits, giving them a foamy or soap-suds appearance.\nsynonyms :Bone marrow foam cells; Large vacuolated foam cells ('NP cells') on bone marrow biopsy; Large vacuolated foam cells on bone marrow biopsy\n"}


{'id': 'HP_0004334', 'url': 'http://purl.obolibrary.org/obo/HP_0004334', 'lbl': 'Dermal atrophy', 'desc': 'label: Dermal atrophy\ndefinition : Partial or complete wasting (atrophy) of the skin.\nsynonyms :Atrophic skin; Skin atrophy; Skin degeneration\n'}


{'id': 'HP_0004336', 'url': 'http://purl.obolibrary.org/obo/HP_0004336', 'lbl': 'Myelin outfoldings', 'desc': 'label: Myelin outfoldings\ndefinition : The presence of excessive redundant myelin in the peripheral nerve sheath.\nsynonyms :Excessive focal folding of myelin sheaths; Irregular myelin foldings\n'}


{'id': 'HP_0004337', 'url': 'http://purl.obolibrary.org/obo/HP_0004337', 'lbl': 'Abnormality of amino acid metabolism', 'desc': 'label: Abnormality of amino acid metabolism\ndefinition : Abnormality of an amino acid metabolic process.\nsynonyms :Amino acid levels abnormal\n'}


{'id': 'HP_0004338', 'url': 'http://purl.obolibrary.org/obo/HP_0004338', 'lbl': 'Abnormal circulating aromatic amino acid concentration', 'desc': 'label: Abnormal circulating aromatic amino acid concentration\ndefinition : Any deviation from the normal concentration of a aromatic amino acid in the blood circulation.\nsynonyms :Abnormality of aromatic amino acid family metabolism\n'}


{'id': 'HP_0004339', 'url': 'http://purl.obolibrary.org/obo/HP_0004339', 'lbl': 'Abnormal circulating sulfur amino acid concentration', 'desc': 'label: Abnormal circulating sulfur amino acid concentration\ndefinition : Any deviation from the normal concentration of a sulfur amino acid in the blood circulation.\nsynonyms :Abnormal circulating sulphur amino acid concentration; Abnormality of sulfur-containing amino acids\n'}


{'id': 'HP_0004340', 'url': 'http://purl.obolibrary.org/obo/HP_0004340', 'lbl': 'Abnormality of vitamin B metabolism', 'desc': 'label: Abnormality of vitamin B metabolism\ndefinition : \nsynonyms :Abnormality of B-vitamin metabolism\n'}


{'id': 'HP_0004341', 'url': 'http://purl.obolibrary.org/obo/HP_0004341', 'lbl': 'Abnormality of vitamin B12 metabolism', 'desc': 'label: Abnormality of vitamin B12 metabolism\ndefinition : \nsynonyms :Abnormality of the vitamin B12 metabolism\n'}


{'id': 'HP_0004342', 'url': 'http://purl.obolibrary.org/obo/HP_0004342', 'lbl': 'Abnormality of galactoside metabolism', 'desc': 'label: Abnormality of galactoside metabolism\ndefinition : Abnormality of galactoside metabolism. A galactoside is a glycoside (a suger moiety bound to some other moiety) containing galactose.\nsynonyms :\n'}


{'id': 'HP_0004343', 'url': 'http://purl.obolibrary.org/obo/HP_0004343', 'lbl': 'Abnormal glycosphingolipid metabolism', 'desc': 'label: Abnormal glycosphingolipid metabolism\ndefinition : An abnormality of glycosphingolipid metabolism.\nsynonyms :Abnormality of glycosphingolipid metabolism\n'}


{'id': 'HP_0004344', 'url': 'http://purl.obolibrary.org/obo/HP_0004344', 'lbl': 'Abnormality of cerebrosidase metabolism', 'desc': 'label: Abnormality of cerebrosidase metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004345', 'url': 'http://purl.obolibrary.org/obo/HP_0004345', 'lbl': 'Ganglioside accumulation', 'desc': 'label: Ganglioside accumulation\ndefinition : Defects in the lysosomal glycosidases or specific co-activators, result in accumulation of the substrates, such as glycosphingolipids, including gangliosides in GM1 gangliosidosis (Tay-Sachs disease) and GM2 gangliosidosis (Sandhoff disease).\nsynonyms :\n'}


{'id': 'HP_0004347', 'url': 'http://purl.obolibrary.org/obo/HP_0004347', 'lbl': 'Weakness of muscles of respiration', 'desc': 'label: Weakness of muscles of respiration\ndefinition : Reduced function of the muscles required to generate subatmospheric pressure in the thoracic cavity during breathing: the diaphragm, the external intercostal and the interchondral part of the internal intercostal muscles.\nsynonyms :\n'}


{'id': 'HP_0004348', 'url': 'http://purl.obolibrary.org/obo/HP_0004348', 'lbl': 'Abnormality of bone mineral density', 'desc': "label: Abnormality of bone mineral density\ndefinition : This term applies to all changes in bone mineral density which (depending on severity) can be seen on x-rays as a change in density and or structure of the bone. Changes may affect all bones of the organism, just certain bones or only parts of bones and include decreased mineralisation as may be seen in osteoporosis or increased mineralisation and or ossification as in osteopetrosis, exostoses or any kind of atopic calicfications of different origin and distribution. The overall amount of mineralization of the bone-organ can be measured as the amount of matter per cubic centimeter of bones, usually measured by densitometry of the lumbar spine or hip. The measurements are usually reported as g/cm3 or as a Z-score (the number of standard deviations above or below the mean for the patient's age and sex). Note that measurement with this method does not reflect local changes in other bones, and as such might not be correct with regard the hole bone-organ.\nsynonyms :Abnormality of bone mineralisation and ossification\n"}


{'id': 'HP_0004349', 'url': 'http://purl.obolibrary.org/obo/HP_0004349', 'lbl': 'Reduced bone mineral density', 'desc': 'label: Reduced bone mineral density\ndefinition : A reduction of bone mineral density, that is, of the amount of matter per cubic centimeter of bones.\nsynonyms :Decreased bone mineral density; Decreased bone mineral density Z score; Low solidness and mass of the bones\n'}


{'id': 'HP_0004352', 'url': 'http://purl.obolibrary.org/obo/HP_0004352', 'lbl': 'Abnormal circulating purine concentration', 'desc': 'label: Abnormal circulating purine concentration\ndefinition : Any deviation from the normal concentration of a purine in the blood circulation.\nsynonyms :Abnormal circulating purine level\n'}


{'id': 'HP_0004353', 'url': 'http://purl.obolibrary.org/obo/HP_0004353', 'lbl': 'Abnormal circulating pyrimidine concentration', 'desc': 'label: Abnormal circulating pyrimidine concentration\ndefinition : Any deviation from the normal concentration of a pyrimidine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0004354', 'url': 'http://purl.obolibrary.org/obo/HP_0004354', 'lbl': 'Abnormal circulating carboxylic acid concentration', 'desc': 'label: Abnormal circulating carboxylic acid concentration\ndefinition : Any deviation from the normal concentration of a carboxylic acid in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0004355', 'url': 'http://purl.obolibrary.org/obo/HP_0004355', 'lbl': 'obsolete Abnormality of proteoglycan metabolism', 'desc': 'label: obsolete Abnormality of proteoglycan metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004356', 'url': 'http://purl.obolibrary.org/obo/HP_0004356', 'lbl': 'Abnormality of lysosomal metabolism', 'desc': 'label: Abnormality of lysosomal metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004357', 'url': 'http://purl.obolibrary.org/obo/HP_0004357', 'lbl': 'Abnormal circulating leucine concentration', 'desc': 'label: Abnormal circulating leucine concentration\ndefinition : Any deviation from the normal circulation of leucine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0004358', 'url': 'http://purl.obolibrary.org/obo/HP_0004358', 'lbl': 'Abnormality of superoxide metabolism', 'desc': 'label: Abnormality of superoxide metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004359', 'url': 'http://purl.obolibrary.org/obo/HP_0004359', 'lbl': 'Abnormal circulating fatty-acid concentration', 'desc': 'label: Abnormal circulating fatty-acid concentration\ndefinition : A deviation from the normal concentration of a fatty acid in the blood circulation.\nsynonyms :Abnormality of fatty acid metabolism; Fatty acids abnormal\n'}


{'id': 'HP_0004360', 'url': 'http://purl.obolibrary.org/obo/HP_0004360', 'lbl': 'Abnormality of acid-base homeostasis', 'desc': 'label: Abnormality of acid-base homeostasis\ndefinition : An abnormality of the balance or maintenance of the balance of acids and bases in bodily fluids, resulting in an abnormal pH.\nsynonyms :Acid base imbalance\n'}


{'id': 'HP_0004361', 'url': 'http://purl.obolibrary.org/obo/HP_0004361', 'lbl': 'Abnormal circulating leptin concentration', 'desc': 'label: Abnormal circulating leptin concentration\ndefinition : An abnormal concentration of leptin in the blood.\nsynonyms :Abnormality of circulating leptin level\n'}


{'id': 'HP_0004362', 'url': 'http://purl.obolibrary.org/obo/HP_0004362', 'lbl': 'Abnormality of enteric ganglion morphology', 'desc': "label: Abnormality of enteric ganglion morphology\ndefinition : An abnormality of the enteric nervous system, which comprises two types of ganglia, the myenteric (Auerbach's) and submucosal (Meissner's) plexuses. The enteric nervous system functions to control gut movement, fluid exchange between the gut and its lumen, and local blood flow.\nsynonyms :Abnormality of the enteric ganglia\n"}


{'id': 'HP_0004363', 'url': 'http://purl.obolibrary.org/obo/HP_0004363', 'lbl': 'Abnormal circulating calcium concentration', 'desc': 'label: Abnormal circulating calcium concentration\ndefinition : Any deviation from the normal concentration of calcium in the blood circulation.\nsynonyms :Abnormal blood calcium concentration; Abnormal blood calcium levels; Abnormal circulating Ca concentration; Abnormal circulating Ca2+ concentration\n'}


{'id': 'HP_0004364', 'url': 'http://purl.obolibrary.org/obo/HP_0004364', 'lbl': 'Abnormal circulating nitrogen compound concentration', 'desc': 'label: Abnormal circulating nitrogen compound concentration\ndefinition : Any deviation from the normal concentration of a nitrogen compound in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0004365', 'url': 'http://purl.obolibrary.org/obo/HP_0004365', 'lbl': 'Abnormal circulating tryptophan concentration', 'desc': 'label: Abnormal circulating tryptophan concentration\ndefinition : Any deviation from the normal concentration of tryptophan in the blood circulation.\nsynonyms :Abnormality of tryptophan metabolism\n'}


{'id': 'HP_0004366', 'url': 'http://purl.obolibrary.org/obo/HP_0004366', 'lbl': 'Abnormality of glycolysis', 'desc': 'label: Abnormality of glycolysis\ndefinition : An abnormality of glycolysis.\nsynonyms :\n'}


{'id': 'HP_0004367', 'url': 'http://purl.obolibrary.org/obo/HP_0004367', 'lbl': 'obsolete Abnormality of glycoprotein metabolism', 'desc': 'label: obsolete Abnormality of glycoprotein metabolism\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004368', 'url': 'http://purl.obolibrary.org/obo/HP_0004368', 'lbl': 'Increased circulating purine concentration', 'desc': 'label: Increased circulating purine concentration\ndefinition : Abnormally elevated concentration of a purine compound. Purine compounds are aromatic heterocyclic compounds containing a purine moiety, which is formed a pyrimidine-ring ring fused to an imidazole ring.\nsynonyms :Increased purine level; Increased purine levels\n'}


{'id': 'HP_0004369', 'url': 'http://purl.obolibrary.org/obo/HP_0004369', 'lbl': 'Decreased circulating purine concentration', 'desc': 'label: Decreased circulating purine concentration\ndefinition : Abnormally reduced concentration of a purine compound. Purine compounds are aromatic heterocyclic compounds containing a purine moiety, which is formed a pyrimidine-ring ring fused to an imidazole ring.\nsynonyms :Decreased purine level; Decreased purine levels\n'}


{'id': 'HP_0004370', 'url': 'http://purl.obolibrary.org/obo/HP_0004370', 'lbl': 'Abnormality of temperature regulation', 'desc': 'label: Abnormality of temperature regulation\ndefinition : An abnormality of temperature homeostasis.\nsynonyms :Abnormality of temperature regulation; Poor temperature regulation; Body temperature changes\n'}


{'id': 'HP_0004371', 'url': 'http://purl.obolibrary.org/obo/HP_0004371', 'lbl': 'Abnormality of glycosaminoglycan metabolism', 'desc': 'label: Abnormality of glycosaminoglycan metabolism\ndefinition : Abnormality of glycosaminoglycan metabolism.\nsynonyms :\n'}


{'id': 'HP_0004372', 'url': 'http://purl.obolibrary.org/obo/HP_0004372', 'lbl': 'Reduced consciousness/confusion', 'desc': 'label: Reduced consciousness/confusion\ndefinition : \nsynonyms :Disturbances of consciousness; Lowered consciousness; Reduced consciousness/confusion\n'}


{'id': 'HP_0004373', 'url': 'http://purl.obolibrary.org/obo/HP_0004373', 'lbl': 'Focal dystonia', 'desc': 'label: Focal dystonia\ndefinition : A type of dystonia that is localized to a specific part of the body.\nsynonyms :\n'}


{'id': 'HP_0004374', 'url': 'http://purl.obolibrary.org/obo/HP_0004374', 'lbl': 'Hemiplegia/hemiparesis', 'desc': 'label: Hemiplegia/hemiparesis\ndefinition : Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a severe or complete loss of strength, whereas hemiparesis refers to a relatively mild loss of strength.\nsynonyms :Paralysis or weakness of one side of body\n'}


{'id': 'HP_0004375', 'url': 'http://purl.obolibrary.org/obo/HP_0004375', 'lbl': 'Neoplasm of the nervous system', 'desc': 'label: Neoplasm of the nervous system\ndefinition : A tumor (abnormal growth of tissue) of the nervous system.\nsynonyms :Tumor of the nervous system; Tumour of the nervous system; Neoplasia of the nervous system; Nervous system cancer\n'}


{'id': 'HP_0004376', 'url': 'http://purl.obolibrary.org/obo/HP_0004376', 'lbl': 'Neuroblastic tumor', 'desc': 'label: Neuroblastic tumor\ndefinition : A family of tumors arising in the embryonal remnants of the sympathetic nervous system, which includes neuroblastoma, ganglioneuroblastoma, and ganglioneuroma.\nsynonyms :Neuroblastic tumour\n'}


{'id': 'HP_0004377', 'url': 'http://purl.obolibrary.org/obo/HP_0004377', 'lbl': 'Hematological neoplasm', 'desc': 'label: Hematological neoplasm\ndefinition : Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue).\nsynonyms :Blood tumor; Blood tumour; Haematological neoplasm\n'}


{'id': 'HP_0004378', 'url': 'http://purl.obolibrary.org/obo/HP_0004378', 'lbl': 'Abnormality of the anus', 'desc': 'label: Abnormality of the anus\ndefinition : Abnormality of the anal canal.\nsynonyms :Abnormality of the anus\n'}


{'id': 'HP_0004379', 'url': 'http://purl.obolibrary.org/obo/HP_0004379', 'lbl': 'Abnormality of alkaline phosphatase level', 'desc': 'label: Abnormality of alkaline phosphatase level\ndefinition : An abnormality of alkaline phosphatase level.\nsynonyms :Abnormality of ALP level; Abnormality of alkaline phosphatase activity; Alkaline phosphatase abnormal\n'}


{'id': 'HP_0004380', 'url': 'http://purl.obolibrary.org/obo/HP_0004380', 'lbl': 'Aortic valve calcification', 'desc': 'label: Aortic valve calcification\ndefinition : Deposition of calcium salts in the aortic valve.\nsynonyms :\n'}


{'id': 'HP_0004381', 'url': 'http://purl.obolibrary.org/obo/HP_0004381', 'lbl': 'Supravalvular aortic stenosis', 'desc': 'label: Supravalvular aortic stenosis\ndefinition : A pathological narrowing in the region above the aortic valve associated with restricted left ventricular outflow.\nsynonyms :\n'}


{'id': 'HP_0004382', 'url': 'http://purl.obolibrary.org/obo/HP_0004382', 'lbl': 'Mitral valve calcification', 'desc': 'label: Mitral valve calcification\ndefinition : Abnormal calcification of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0004383', 'url': 'http://purl.obolibrary.org/obo/HP_0004383', 'lbl': 'Hypoplastic left heart', 'desc': 'label: Hypoplastic left heart\ndefinition : Underdevelopment of the left side of the heart. May include atresia of the aortic or mitral orifice and hypoplasia of the ascending aorta.\nsynonyms :Heart left ventricle hypoplasia; Left ventricular hypoplasia; Underdeveloped left heart\n'}


{'id': 'HP_0004384', 'url': 'http://purl.obolibrary.org/obo/HP_0004384', 'lbl': 'Type I truncus arteriosus', 'desc': 'label: Type I truncus arteriosus\ndefinition : Truncus arteriosus (single great artery leaving the base of the heart, giving rise to the coronary, pulmonary, and systemic arteries) with a short pulmonary trunk arises from the truncus arteriosus, giving rise to both pulmonary arteries.\nsynonyms :Persistent truncus arteriosus type I; Type 1 truncus arteriosus\n'}


{'id': 'HP_0004385', 'url': 'http://purl.obolibrary.org/obo/HP_0004385', 'lbl': 'Protracted diarrhea', 'desc': 'label: Protracted diarrhea\ndefinition : \nsynonyms :Protracted diarrhoea\n'}


{'id': 'HP_0004386', 'url': 'http://purl.obolibrary.org/obo/HP_0004386', 'lbl': 'Gastrointestinal inflammation', 'desc': 'label: Gastrointestinal inflammation\ndefinition : Inflammation of the alimentary part of the gastrointestinal system.\nsynonyms :GI inflammation; Gastrointestinal inflammation\n'}


{'id': 'HP_0004387', 'url': 'http://purl.obolibrary.org/obo/HP_0004387', 'lbl': 'Enterocolitis', 'desc': 'label: Enterocolitis\ndefinition : An inflammation of the colon and small intestine. However, most conditions are either categorized as Enteritis (inflammation of the small intestine) or Colitis (inflammation of the large intestine).\nsynonyms :\n'}


{'id': 'HP_0004388', 'url': 'http://purl.obolibrary.org/obo/HP_0004388', 'lbl': 'Microcolon', 'desc': 'label: Microcolon\ndefinition : A colon of abnormally small caliber.\nsynonyms :Microcolon on contrast enema\n'}


{'id': 'HP_0004389', 'url': 'http://purl.obolibrary.org/obo/HP_0004389', 'lbl': 'Intestinal pseudo-obstruction', 'desc': 'label: Intestinal pseudo-obstruction\ndefinition : A functional rather than mechanical obstruction of the intestines, associated with manifestations that resemble those caused by an intestinal obstruction, including distension, abdominal pain, nausea, vomiting, constipation or diarrhea, in an individual in whom a mechanical blockage has been excluded.\nsynonyms :Intestinal pseudoobstruction\n'}


{'id': 'HP_0004390', 'url': 'http://purl.obolibrary.org/obo/HP_0004390', 'lbl': 'Hamartomatous polyposis', 'desc': 'label: Hamartomatous polyposis\ndefinition : Polyp-like protrusions which are histologically hamartomas. These can occur throughout the gastrointestinal tract. Hamartomatous polyps are composed of the normal cellular elements of the gastrointestinal tract, but have a markedly distorted architecture.\nsynonyms :Gastrointestinal hamartoma; Hamartomatous polyps; Gastrointestinal hamartomatous polyps\n'}


{'id': 'HP_0004392', 'url': 'http://purl.obolibrary.org/obo/HP_0004392', 'lbl': 'Prune belly', 'desc': 'label: Prune belly\ndefinition : A kind of congenital defect of the anterior abdominal wall in which the intestines are evident through the thin, lax, and protruding abdominal wall in affected infants.\nsynonyms :Prune belly\n'}


{'id': 'HP_0004394', 'url': 'http://purl.obolibrary.org/obo/HP_0004394', 'lbl': 'Multiple gastric polyps', 'desc': 'label: Multiple gastric polyps\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004395', 'url': 'http://purl.obolibrary.org/obo/HP_0004395', 'lbl': 'Malnutrition', 'desc': 'label: Malnutrition\ndefinition : A deficiency in the intake of energy and nutrients.\nsynonyms :Malnutrition\n'}


{'id': 'HP_0004396', 'url': 'http://purl.obolibrary.org/obo/HP_0004396', 'lbl': 'Poor appetite', 'desc': 'label: Poor appetite\ndefinition : A reduced desire to eat.\nsynonyms :Decreased appetite; Loss of appetite; Poor appetite; No appetite\n'}


{'id': 'HP_0004397', 'url': 'http://purl.obolibrary.org/obo/HP_0004397', 'lbl': 'Ectopic anus', 'desc': 'label: Ectopic anus\ndefinition : Abnormal displacement or malposition of the anus.\nsynonyms :Abnormal anus position; Anus malposition\n'}


{'id': 'HP_0004398', 'url': 'http://purl.obolibrary.org/obo/HP_0004398', 'lbl': 'Peptic ulcer', 'desc': "label: Peptic ulcer\ndefinition : The term peptic ulcer refers to acid peptic injury of the digestive tract, resulting in mucosal break reaching the submucosa. Peptic ulcers are usually located in the stomach or proximal duodenum, but they can also be found in the oesophagus or Meckel's diverticulum. Infection with Helicobacter pylori and the use of non steroidal antiinflammatory drugs (NSAIDs) or aspirin are the main risk factors of both gastric and duodenal peptic ulcers.\nsynonyms :Sore in the lining of gastrointestinal tract\n"}


{'id': 'HP_0004399', 'url': 'http://purl.obolibrary.org/obo/HP_0004399', 'lbl': 'Congenital pyloric atresia', 'desc': 'label: Congenital pyloric atresia\ndefinition : Congenital atresia of the pylorus.\nsynonyms :\n'}


{'id': 'HP_0004400', 'url': 'http://purl.obolibrary.org/obo/HP_0004400', 'lbl': 'Abnormality of the pylorus', 'desc': 'label: Abnormality of the pylorus\ndefinition : An abnormality of the pylorus.\nsynonyms :\n'}


{'id': 'HP_0004401', 'url': 'http://purl.obolibrary.org/obo/HP_0004401', 'lbl': 'Meconium ileus', 'desc': 'label: Meconium ileus\ndefinition : Obstruction of the intestine due to abnormally thick meconium.\nsynonyms :Meconium ileus in neonates; Distal intestinal obstruction syndrome; Meconium ileus on ultrasonography\n'}


{'id': 'HP_0004403', 'url': 'http://purl.obolibrary.org/obo/HP_0004403', 'lbl': 'Proximal esophageal atresia', 'desc': 'label: Proximal esophageal atresia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004404', 'url': 'http://purl.obolibrary.org/obo/HP_0004404', 'lbl': 'Abnormal nipple morphology', 'desc': 'label: Abnormal nipple morphology\ndefinition : An abnormality of the nipple.\nsynonyms :Abnormality of the nipple\n'}


{'id': 'HP_0004405', 'url': 'http://purl.obolibrary.org/obo/HP_0004405', 'lbl': 'Prominent nipples', 'desc': 'label: Prominent nipples\ndefinition : \nsynonyms :Prominent nipples\n'}


{'id': 'HP_0004406', 'url': 'http://purl.obolibrary.org/obo/HP_0004406', 'lbl': 'Spontaneous, recurrent epistaxis', 'desc': 'label: Spontaneous, recurrent epistaxis\ndefinition : \nsynonyms :Recurrent epistaxes; Recurrent epistaxis; Recurring nosebleed; Spontaneous, recurrent nosebleed\n'}


{'id': 'HP_0004407', 'url': 'http://purl.obolibrary.org/obo/HP_0004407', 'lbl': 'Bony paranasal bossing', 'desc': 'label: Bony paranasal bossing\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004408', 'url': 'http://purl.obolibrary.org/obo/HP_0004408', 'lbl': 'Abnormality of the sense of smell', 'desc': 'label: Abnormality of the sense of smell\ndefinition : An anomaly in the ability to perceive and distinguish scents (odors).\nsynonyms :Abnormal sense of smell; Abnormality of olfaction; Abnormality of the sense of smell; Smell defect\n'}


{'id': 'HP_0004409', 'url': 'http://purl.obolibrary.org/obo/HP_0004409', 'lbl': 'Hyposmia', 'desc': 'label: Hyposmia\ndefinition : A decreased sensitivity to odorants (that is, a decreased ability to perceive odors).\nsynonyms :Decreased smell sensation; Sense of smell impaired\n'}


{'id': 'HP_0004411', 'url': 'http://purl.obolibrary.org/obo/HP_0004411', 'lbl': 'Deviated nasal septum', 'desc': 'label: Deviated nasal septum\ndefinition : Positioning of the nasal septum to the right or left in contrast to the normal midline position of the nasal septum.\nsynonyms :Crooked nasal septum; Crooked septum of nose; Deviated nasal septum; Deviated septum of nose\n'}


{'id': 'HP_0004414', 'url': 'http://purl.obolibrary.org/obo/HP_0004414', 'lbl': 'Abnormality of the pulmonary artery', 'desc': 'label: Abnormality of the pulmonary artery\ndefinition : An abnormality of the pulmonary artery.\nsynonyms :Abnormality of lung artery\n'}


{'id': 'HP_0004415', 'url': 'http://purl.obolibrary.org/obo/HP_0004415', 'lbl': 'Pulmonary artery stenosis', 'desc': 'label: Pulmonary artery stenosis\ndefinition : An abnormal narrowing or constriction of the pulmonary artery, in the main pulmonary artery and/or in the left or right pulmonary artery branches.\nsynonyms :Narrowing of lung artery\n'}


{'id': 'HP_0004416', 'url': 'http://purl.obolibrary.org/obo/HP_0004416', 'lbl': 'Precocious atherosclerosis', 'desc': 'label: Precocious atherosclerosis\ndefinition : \nsynonyms :Premature plaque build-up in arteries; Premature atherosclerosis\n'}


{'id': 'HP_0004417', 'url': 'http://purl.obolibrary.org/obo/HP_0004417', 'lbl': 'Intermittent claudication', 'desc': 'label: Intermittent claudication\ndefinition : Intermittent claudication is a symptom of peripheral arterial occlusive disease. After having walked over a distance which is individually characteristic, the patients experience pain or cramps in the calves, feet or thighs which typically subsides on standing still.\nsynonyms :\n'}


{'id': 'HP_0004418', 'url': 'http://purl.obolibrary.org/obo/HP_0004418', 'lbl': 'Thrombophlebitis', 'desc': 'label: Thrombophlebitis\ndefinition : Inflammation of a vein associated with venous thrombosis (blood clot formation within the vein).\nsynonyms :\n'}


{'id': 'HP_0004419', 'url': 'http://purl.obolibrary.org/obo/HP_0004419', 'lbl': 'Recurrent thrombophlebitis', 'desc': 'label: Recurrent thrombophlebitis\ndefinition : Repeated episodes of inflammation of a vein associated with venous thrombosis (blood clot formation within the vein).\nsynonyms :Recurrent phlebitis; Recurrent thrombosis\n'}


{'id': 'HP_0004420', 'url': 'http://purl.obolibrary.org/obo/HP_0004420', 'lbl': 'Arterial thrombosis', 'desc': 'label: Arterial thrombosis\ndefinition : The formation of a blood clot inside an artery.\nsynonyms :Blood clot in artery\n'}


{'id': 'HP_0004421', 'url': 'http://purl.obolibrary.org/obo/HP_0004421', 'lbl': 'Elevated systolic blood pressure', 'desc': 'label: Elevated systolic blood pressure\ndefinition : Abnormal increase in systolic blood pressure.\nsynonyms :Elevated systolic BP\n'}


{'id': 'HP_0004422', 'url': 'http://purl.obolibrary.org/obo/HP_0004422', 'lbl': 'Biparietal narrowing', 'desc': 'label: Biparietal narrowing\ndefinition : A narrowing of the biparietal diameter (i.e., of the transverse distance between the protuberances of the two parietal bones of the skull).\nsynonyms :Decreased width of the skull\n'}


{'id': 'HP_0004423', 'url': 'http://purl.obolibrary.org/obo/HP_0004423', 'lbl': 'Cranium bifidum occultum', 'desc': 'label: Cranium bifidum occultum\ndefinition : Cranium bifidum occultum, also known as Catlin mark, is a congenital midline skull defect presenting as an enlarged posterior fontanelle in the upper posterior angle of the parietal bone close to the intersection of the sagittal and lambdoid sutures.1, 2, 3 Cranium bifidum occultum occurs due to a defect in intramembranous ossification, a process through which skull bones (frontal, parietal, squamous temporal and occipital bones superior to the mendosal suture) ossify under a vascularized membrane toward the midline to cover the brain.1, 4, 5 Unlike cranium bifidum cysticum, cranium bifidum occultum does not have herniation of intracranial contents. As the skull grows, the midline cranium bifidum occultum defect is separated into bilateral enlarged parietal foramina (EPF) by a midline osseous bridge.\nsynonyms :\n'}


{'id': 'HP_0004425', 'url': 'http://purl.obolibrary.org/obo/HP_0004425', 'lbl': 'Flat forehead', 'desc': 'label: Flat forehead\ndefinition : A forehead with abnormal flatness.\nsynonyms :Flat forehead; Flattened forehead; Frontal flattening\n'}


{'id': 'HP_0004426', 'url': 'http://purl.obolibrary.org/obo/HP_0004426', 'lbl': 'Abnormal cheek morphology', 'desc': 'label: Abnormal cheek morphology\ndefinition : An abnormality of the cheek- one of two bilateral soft tissue facial structures in the region of the face inferior to the eyes and between the nose and the ear. "Buccal" means relating to the cheek. The cheek is part of the midface\nsynonyms :Abnormality of the cheek; Abnormality of the cheeks; Anomaly of the cheeks; Deformity of the cheeks; Malformation of the cheeks\n'}


{'id': 'HP_0004428', 'url': 'http://purl.obolibrary.org/obo/HP_0004428', 'lbl': 'Elfin facies', 'desc': 'label: Elfin facies\ndefinition : This is a description previously used to describe a facial form characterized by a short, upturned nose, wide mouth, widely spaced eyes, and full cheeks. Because of the imprecision in this definition it is preferable to describe these features precisely. This term is retained because it was often used in the past, but it should not be used for new annotations.\nsynonyms :Elf-like facial appearance; Elf-like facial features; Leprechaun facies\n'}


{'id': 'HP_0004429', 'url': 'http://purl.obolibrary.org/obo/HP_0004429', 'lbl': 'Recurrent viral infections', 'desc': 'label: Recurrent viral infections\ndefinition : Increased susceptibility to viral infections, as manifested by recurrent episodes of viral infection.\nsynonyms :\n'}


{'id': 'HP_0004430', 'url': 'http://purl.obolibrary.org/obo/HP_0004430', 'lbl': 'Severe combined immunodeficiency', 'desc': 'label: Severe combined immunodeficiency\ndefinition : A type of primary immune deficiency that is characterized by a more severe defect in both the T- and B-lymphocyte systems.\nsynonyms :Immunodeficiency, severe combined\n'}


{'id': 'HP_0004431', 'url': 'http://purl.obolibrary.org/obo/HP_0004431', 'lbl': 'Complement deficiency', 'desc': 'label: Complement deficiency\ndefinition : An immunodeficiency defined by the absent or suboptimal functioning of one of the complement system proteins.\nsynonyms :\n'}


{'id': 'HP_0004432', 'url': 'http://purl.obolibrary.org/obo/HP_0004432', 'lbl': 'Agammaglobulinemia', 'desc': 'label: Agammaglobulinemia\ndefinition : A lasting absence of total IgG and total IgA and total IgM in the blood circulation, whereby at most trace quantities can be measured.\nsynonyms :Agammaglobulinaemia\n'}


{'id': 'HP_0004433', 'url': 'http://purl.obolibrary.org/obo/HP_0004433', 'lbl': 'Secretory IgA deficiency', 'desc': 'label: Secretory IgA deficiency\ndefinition : Deficiency of secretory IgA (polymers of 2-4 IgA monomers are linked by two additional chains) and is the primary antibody response at the mucosal level, where it forms immune complexes with pathogens and allergens.\nsynonyms :\n'}


{'id': 'HP_0004434', 'url': 'http://purl.obolibrary.org/obo/HP_0004434', 'lbl': 'Decreased circulating complement C8 concentration', 'desc': 'label: Decreased circulating complement C8 concentration\ndefinition : Concentration of the complement component C8 in the blood circulation below the lower limit of normal.\nsynonyms :C8 deficiency; Decreased serum complement C8\n'}


{'id': 'HP_0004437', 'url': 'http://purl.obolibrary.org/obo/HP_0004437', 'lbl': 'Cranial hyperostosis', 'desc': 'label: Cranial hyperostosis\ndefinition : Excessive growth of the bones of cranium, i.e., of the skull.\nsynonyms :Enlargement of skull bones; Excessive growth of skull bones; Hypertrophy of cranial bones; Overgrowth of skull bones; Thick skull bones; Hyperostosis of cranial bones; Hyperostosis of cranial vault; Increased ossification of cranial bones\n'}


{'id': 'HP_0004438', 'url': 'http://purl.obolibrary.org/obo/HP_0004438', 'lbl': 'Hyperostosis frontalis interna', 'desc': 'label: Hyperostosis frontalis interna\ndefinition : Bony overgrowth of the internal (endosteal) surface of the frontal bone.\nsynonyms :Enlargement of the inner surface of the frontal bone; Hypertrophy of the internal surface of the frontal bone; Increased ossification of the internal surface of the frontal bone; Overgrowth of the inside of the frontal bone; Thick inner surface of the frontal bone; Thick internal surface of the frontal bone; Excessive growth of inner surface of the frontal bone; Hyperostosis of the internal surface of the frontal bone; Overgrowth of the inner surface of the frontal bone\n'}


{'id': 'HP_0004439', 'url': 'http://purl.obolibrary.org/obo/HP_0004439', 'lbl': 'Craniofacial dysostosis', 'desc': 'label: Craniofacial dysostosis\ndefinition : A characteristic appearance resulting from defective ossification of craniofacial bones.\nsynonyms :Crouzon syndrome\n'}


{'id': 'HP_0004440', 'url': 'http://purl.obolibrary.org/obo/HP_0004440', 'lbl': 'Coronal craniosynostosis', 'desc': 'label: Coronal craniosynostosis\ndefinition : Premature closure of the coronal suture of skull.\nsynonyms :Coronal suture craniosynostosis; Coronal suture synostosis; Craniosynostosis of coronal suture\n'}


{'id': 'HP_0004442', 'url': 'http://purl.obolibrary.org/obo/HP_0004442', 'lbl': 'Sagittal craniosynostosis', 'desc': 'label: Sagittal craniosynostosis\ndefinition : A kind of craniosynostosis affecting the sagittal suture.\nsynonyms :Craniosynostosis, sagittal; Craniosynostosis, sagittal suture; Early closure of midline skull joint; Midline skull joint closes early; Sagittal suture synostosis\n'}


{'id': 'HP_0004443', 'url': 'http://purl.obolibrary.org/obo/HP_0004443', 'lbl': 'Lambdoidal craniosynostosis', 'desc': 'label: Lambdoidal craniosynostosis\ndefinition : A kind of craniosynostosis affecting the lambdoidal suture.\nsynonyms :Lambdoid suture craniosynostosis; Lambdoid suture synostosis\n'}


{'id': 'HP_0004444', 'url': 'http://purl.obolibrary.org/obo/HP_0004444', 'lbl': 'Spherocytosis', 'desc': 'label: Spherocytosis\ndefinition : The presence of erythrocytes that are sphere-shaped.\nsynonyms :\n'}


{'id': 'HP_0004445', 'url': 'http://purl.obolibrary.org/obo/HP_0004445', 'lbl': 'Elliptocytosis', 'desc': 'label: Elliptocytosis\ndefinition : The presence of elliptical, cigar-shaped erythrocytes on peripheral blood smear.\nsynonyms :Ovalocytes; Ovalocytosis; Elliptocyte; Hereditary elliptocytosis\n'}


{'id': 'HP_0004446', 'url': 'http://purl.obolibrary.org/obo/HP_0004446', 'lbl': 'Stomatocytosis', 'desc': 'label: Stomatocytosis\ndefinition : The presence of erythrocytes with a mouth-shaped (stoma) area of central pallor on peripheral blood smear.\nsynonyms :Red cell stomatocytosis; erythrocyte stomatocytes\n'}


{'id': 'HP_0004447', 'url': 'http://purl.obolibrary.org/obo/HP_0004447', 'lbl': 'Poikilocytosis', 'desc': 'label: Poikilocytosis\ndefinition : The presence of abnormally shaped erythrocytes.\nsynonyms :\n'}


{'id': 'HP_0004448', 'url': 'http://purl.obolibrary.org/obo/HP_0004448', 'lbl': 'Fulminant hepatic failure', 'desc': 'label: Fulminant hepatic failure\ndefinition : Hepatic failure refers to the inability of the liver to perform its normal synthetic and metabolic functions, which can result in coagulopathy and alteration in the mental status of a previously healthy individual. Hepatic failure is defined as fulminant if there is onset of encephalopathy within 4 weeks of the onset of symptoms in a patient with a previously healthy liver.\nsynonyms :\n'}


{'id': 'HP_0004450', 'url': 'http://purl.obolibrary.org/obo/HP_0004450', 'lbl': 'Preauricular skin furrow', 'desc': 'label: Preauricular skin furrow\ndefinition : A groove of the skin immediately in front of the ear.\nsynonyms :Preauricular skin furrows; Preauricular skin groove; Preauricular skin sulcus; Skin groove in front of the ear; Skin sulcus in front of the ear\n'}


{'id': 'HP_0004451', 'url': 'http://purl.obolibrary.org/obo/HP_0004451', 'lbl': 'Postauricular skin tag', 'desc': 'label: Postauricular skin tag\ndefinition : A rudimentary tag of ear tissue often containing a core of cartilage and located just in back of the auricle (outer part of the ear).\nsynonyms :Postauricular acrochordon; Postauricular fibroepithelial polyp; Skin tag behind the ear\n'}


{'id': 'HP_0004452', 'url': 'http://purl.obolibrary.org/obo/HP_0004452', 'lbl': 'Abnormality of the middle ear ossicles', 'desc': 'label: Abnormality of the middle ear ossicles\ndefinition : An abnormality of the middle-ear ossicles (three small bones called malleus, incus, and stapes) that are contained within the middle ear and serve to transmit sounds from the air to the fluid-filled labyrinth (cochlea).\nsynonyms :Malformed ossicles; Ossicular malformation\n'}


{'id': 'HP_0004453', 'url': 'http://purl.obolibrary.org/obo/HP_0004453', 'lbl': 'Overfolding of the superior helices', 'desc': 'label: Overfolding of the superior helices\ndefinition : A condition in which the superior portion of the helix is folded over to a greater degree than normal.\nsynonyms :Overfolding of superior helix\n'}


{'id': 'HP_0004454', 'url': 'http://purl.obolibrary.org/obo/HP_0004454', 'lbl': 'Abnormal middle ear reflexes', 'desc': 'label: Abnormal middle ear reflexes\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004458', 'url': 'http://purl.obolibrary.org/obo/HP_0004458', 'lbl': 'Dilatated internal auditory canal', 'desc': 'label: Dilatated internal auditory canal\ndefinition : The presence of a dilated inner part of external acoustic meatus.\nsynonyms :Bulbous internal auditory canal; Enlarged internal auditory canal\n'}


{'id': 'HP_0004459', 'url': 'http://purl.obolibrary.org/obo/HP_0004459', 'lbl': 'Exostosis of the external auditory canal', 'desc': 'label: Exostosis of the external auditory canal\ndefinition : A benign bony growth projecting outward from a bone surface within the external auditory canal.\nsynonyms :External auditory canal exostoses\n'}


{'id': 'HP_0004461', 'url': 'http://purl.obolibrary.org/obo/HP_0004461', 'lbl': 'Congenital earlobe sinuses', 'desc': 'label: Congenital earlobe sinuses\ndefinition : Pits in the earlobes at the location where ears are typically pierced for earrings.\nsynonyms :\n'}


{'id': 'HP_0004463', 'url': 'http://purl.obolibrary.org/obo/HP_0004463', 'lbl': 'Absent brainstem auditory responses', 'desc': 'label: Absent brainstem auditory responses\ndefinition : Lack of measurable response to stimulation of auditory evoked potentials.\nsynonyms :No auditory brainstem response\n'}


{'id': 'HP_0004464', 'url': 'http://purl.obolibrary.org/obo/HP_0004464', 'lbl': 'Postauricular pit', 'desc': 'label: Postauricular pit\ndefinition : Benign congenital lesion of the postauricular soft tissue consisting of a blind-ending narrow tube or pit.\nsynonyms :Pit behind the ear; Postauricular earpits; Postauricular fistula; Posterior auricular pit; Posterior auricular sinus\n'}


{'id': 'HP_0004466', 'url': 'http://purl.obolibrary.org/obo/HP_0004466', 'lbl': 'Prolonged brainstem auditory evoked potentials', 'desc': 'label: Prolonged brainstem auditory evoked potentials\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004467', 'url': 'http://purl.obolibrary.org/obo/HP_0004467', 'lbl': 'Preauricular pit', 'desc': 'label: Preauricular pit\ndefinition : Small indentation anterior to the insertion of the ear.\nsynonyms :Ear pit; Pit in front of the ear; Preauricular earpits; Preauricular fistulas; Preauricular pits; Preauricular sinus\n'}


{'id': 'HP_0004468', 'url': 'http://purl.obolibrary.org/obo/HP_0004468', 'lbl': 'Anomalous tracheal cartilage', 'desc': 'label: Anomalous tracheal cartilage\ndefinition : An abnormality of the C-shaped rings of hyaline cartilage, normally 16 to 20 in number, that occupy the anterior two-thirds of the circumference of the trachea (the posterior portion of the ring is completed by fibrous and smooth muscle tissue).\nsynonyms :Abnormal tracheal cartilaginous ring\n'}


{'id': 'HP_0004469', 'url': 'http://purl.obolibrary.org/obo/HP_0004469', 'lbl': 'Chronic bronchitis', 'desc': 'label: Chronic bronchitis\ndefinition : Chronic inflammation of the bronchi.\nsynonyms :\n'}


{'id': 'HP_0004470', 'url': 'http://purl.obolibrary.org/obo/HP_0004470', 'lbl': 'Atretic occipital cephalocele', 'desc': 'label: Atretic occipital cephalocele\ndefinition : A congenital defect in the occipital region of the skull, covered by skin of the scalp and containing meninges or remnants of glial or neural tissues.\nsynonyms :\n'}


{'id': 'HP_0004471', 'url': 'http://purl.obolibrary.org/obo/HP_0004471', 'lbl': 'Aplasia cutis congenita over the scalp vertex', 'desc': 'label: Aplasia cutis congenita over the scalp vertex\ndefinition : A developmental defect resulting in the congenital absence of skin on the scalp vertex, often just lateral to the midline.\nsynonyms :Absent cutis congenita of vertex; Aplasia cutis congenita of vertex\n'}


{'id': 'HP_0004472', 'url': 'http://purl.obolibrary.org/obo/HP_0004472', 'lbl': 'Mandibular hyperostosis', 'desc': 'label: Mandibular hyperostosis\ndefinition : Hyperostosis (bony overgrowth) of the mandible.\nsynonyms :Excessive growth of mandibular bone; Overgrowth of mandibular bone; Thick lower jaw bone; Thick mandibular bone; Hyperostosis of lower jaw; Hyperostosis of mandibular bone; Increased ossification of mandibular bone; Increased ossification of lower jaw; Increased ossification of mandible\n'}


{'id': 'HP_0004474', 'url': 'http://purl.obolibrary.org/obo/HP_0004474', 'lbl': 'Persistent open anterior fontanelle', 'desc': 'label: Persistent open anterior fontanelle\ndefinition : The anterior fontanelle generally ossifies by around the 18th month of life. A persistent open anterior fontanelle is diagnosed if closure is delayed beyond this age.\nsynonyms :Front fontanelle stays open; Persistent, open anterior fontanel; Anterior fontanelle open in adults\n'}


{'id': 'HP_0004476', 'url': 'http://purl.obolibrary.org/obo/HP_0004476', 'lbl': 'Aplasia cutis congenita over parietal area', 'desc': 'label: Aplasia cutis congenita over parietal area\ndefinition : A developmental defect resulting in the congenital absence of skin on the scalp in the parietal area.\nsynonyms :Absent cutis congenita over parietal area\n'}


{'id': 'HP_0004478', 'url': 'http://purl.obolibrary.org/obo/HP_0004478', 'lbl': 'Ethmoidal encephalocele', 'desc': 'label: Ethmoidal encephalocele\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004481', 'url': 'http://purl.obolibrary.org/obo/HP_0004481', 'lbl': 'Progressive macrocephaly', 'desc': 'label: Progressive macrocephaly\ndefinition : The progressive development of an abnormally large skull.\nsynonyms :Macrocephaly, progressive; Progressively abnormally enlarging cranium; Progressively abnormally enlarging skull\n'}


{'id': 'HP_0004482', 'url': 'http://purl.obolibrary.org/obo/HP_0004482', 'lbl': 'Relative macrocephaly', 'desc': 'label: Relative macrocephaly\ndefinition : A relatively mild degree of macrocephaly in which the head circumference is not above two standard deviations from the mean, but appears dysproportionately large when other factors such as body stature are taken into account.\nsynonyms :Disproportionately large head; Macrocephaly, relative; Relatively large head\n'}


{'id': 'HP_0004484', 'url': 'http://purl.obolibrary.org/obo/HP_0004484', 'lbl': 'Craniofacial asymmetry', 'desc': 'label: Craniofacial asymmetry\ndefinition : Asymmetry of the bones of the skull and the face.\nsynonyms :Uneven craniofacial structures; Abnormality of craniofacial shape; Malformation of craniofacial shape\n'}


{'id': 'HP_0004485', 'url': 'http://purl.obolibrary.org/obo/HP_0004485', 'lbl': 'Cessation of head growth', 'desc': 'label: Cessation of head growth\ndefinition : Stagnation of head growth seen as flattening of the head circumference curve.\nsynonyms :Skull stopped growing; Cranium stopped growing; Head stopped growing\n'}


{'id': 'HP_0004487', 'url': 'http://purl.obolibrary.org/obo/HP_0004487', 'lbl': 'Acrobrachycephaly', 'desc': 'label: Acrobrachycephaly\ndefinition : An abnormality of head shape characterized by the presence of a short, wide head as well as a pointy or conical form of the top of the head owing to premature closure of the coronal and lambdoid sutures.\nsynonyms :\n'}


{'id': 'HP_0004488', 'url': 'http://purl.obolibrary.org/obo/HP_0004488', 'lbl': 'Macrocephaly at birth', 'desc': 'label: Macrocephaly at birth\ndefinition : The presence of an abnormally large skull with onset at birth.\nsynonyms :Big head present at birth; Big head present since birth; Congenital large head; Large head present at birth; Large head present since birth; Big cranium present at birth; Big cranium present since birth; Big skull present at birth; Big skull present since birth; Congenital large cranium; Congenital large skull; Congenital macrocephaly; Head circumference large for gestational age; Large cranium present at birth; Large cranium present since birth; Large skull present at birth; Large skull present since birth\n'}


{'id': 'HP_0004490', 'url': 'http://purl.obolibrary.org/obo/HP_0004490', 'lbl': 'Calvarial hyperostosis', 'desc': 'label: Calvarial hyperostosis\ndefinition : Excessive growth of the calvaria.\nsynonyms :Enlargement of calvarial bones; Excessive growth of calvarial bones; Hypertrophy of calvarial bones; Overgrowth of calvarial bones; Thick calvarial bones; Hyperostosis of calvarial bones; Increased ossification of calvarial bones; Overgrowth of skullcap\n'}


{'id': 'HP_0004491', 'url': 'http://purl.obolibrary.org/obo/HP_0004491', 'lbl': 'Large posterior fontanelle', 'desc': 'label: Large posterior fontanelle\ndefinition : An enlargement of the posterior fontanelle relative to age-dependent norms.\nsynonyms :Large posterior fontanel\n'}


{'id': 'HP_0004492', 'url': 'http://purl.obolibrary.org/obo/HP_0004492', 'lbl': 'Widely patent fontanelles and sutures', 'desc': 'label: Widely patent fontanelles and sutures\ndefinition : An abnormally increased width of the cranial fontanelles and sutures.\nsynonyms :Widely patent fontanels and sutures\n'}


{'id': 'HP_0004493', 'url': 'http://purl.obolibrary.org/obo/HP_0004493', 'lbl': 'Craniofacial hyperostosis', 'desc': 'label: Craniofacial hyperostosis\ndefinition : Excessive growth of the craniofacial bones.\nsynonyms :Enlargement of craniofacial bones; Excessive growth of craniofacial bones; Hypertrophy of craniofacial bones; Overgrowth of craniofacial bones; Thick craniofacial bones; Excessive bone growth of the skull and face; Hyperostosis of craniofacial bones; Increased ossification of craniofacial bones\n'}


{'id': 'HP_0004495', 'url': 'http://purl.obolibrary.org/obo/HP_0004495', 'lbl': 'obsolete Thin anteverted nares', 'desc': 'label: obsolete Thin anteverted nares\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004496', 'url': 'http://purl.obolibrary.org/obo/HP_0004496', 'lbl': 'obsolete Posterior choanal atresia', 'desc': 'label: obsolete Posterior choanal atresia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0004499', 'url': 'http://purl.obolibrary.org/obo/HP_0004499', 'lbl': 'Chronic rhinitis due to narrow nasal airway', 'desc': 'label: Chronic rhinitis due to narrow nasal airway\ndefinition : \nsynonyms :Chronic nasal inflammation due to narrow nasal airway\n'}


{'id': 'HP_0004502', 'url': 'http://purl.obolibrary.org/obo/HP_0004502', 'lbl': 'Bilateral choanal atresia', 'desc': 'label: Bilateral choanal atresia\ndefinition : Bilateral absence (atresia) of the posterior nasal aperture (choana).\nsynonyms :Bilateral blockage of the rear opening of the nasal cavity; Bilateral obstruction of the rear opening of the nasal cavity\n'}


{'id': 'HP_0004510', 'url': 'http://purl.obolibrary.org/obo/HP_0004510', 'lbl': 'Pancreatic islet-cell hyperplasia', 'desc': 'label: Pancreatic islet-cell hyperplasia\ndefinition : Hyperplasia of the islets of Langerhans, i.e., of the regions of the pancreas that contain its endocrine cells.\nsynonyms :Hyperplastic islets of langerhans; Hypertrophic pancreatic islets; Islet of Langerhans hyperplasia; Islets of langerhans hypertrophy; Pancreatic islet-cell hypertrophy\n'}


{'id': 'HP_0004523', 'url': 'http://purl.obolibrary.org/obo/HP_0004523', 'lbl': 'Long eyebrows', 'desc': 'label: Long eyebrows\ndefinition : Increased length of the hairs of the eyebrows.\nsynonyms :Elongated eyebrow; Increased horizontal length of eyebrow; Increased transverse length of eyebrow; Long eyebrows\n'}


{'id': 'HP_0004524', 'url': 'http://purl.obolibrary.org/obo/HP_0004524', 'lbl': 'Temporal hypotrichosis', 'desc': 'label: Temporal hypotrichosis\ndefinition : Reduced or lacking hair growth in the temporal region (i.e., around the temples on the side of the skull).\nsynonyms :Reduced hair growth in temporal region\n'}


{'id': 'HP_0004527', 'url': 'http://purl.obolibrary.org/obo/HP_0004527', 'lbl': 'Large clumps of pigment irregularly distributed along hair shaft', 'desc': 'label: Large clumps of pigment irregularly distributed along hair shaft\ndefinition : \nsynonyms :Large clumps of pigment irregularly distributed along hair shaft\n'}


{'id': 'HP_0004528', 'url': 'http://purl.obolibrary.org/obo/HP_0004528', 'lbl': 'Generalized hypotrichosis', 'desc': 'label: Generalized hypotrichosis\ndefinition : Reduced or lacking hair growth in a generalized distribution.\nsynonyms :Generalised hypotrichosis; Hypotrichosis, generalised; Hypotrichosis, generalized\n'}