{'id': 'HP_0031283', 'url': 'http://purl.obolibrary.org/obo/HP_0031283', 'lbl': 'Tufted hairs', 'desc': 'label: Tufted hairs\ndefinition : The presence of tufts of 8-15 hairs that appear to emerge from a single follicular orifice.\nsynonyms :\n'}


{'id': 'HP_0031284', 'url': 'http://purl.obolibrary.org/obo/HP_0031284', 'lbl': 'Flushing', 'desc': 'label: Flushing\ndefinition : Recurrent episodes of redness of the skin together with a sensation of warmth or burning of the affected areas of skin.\nsynonyms :\n'}


{'id': 'HP_0031285', 'url': 'http://purl.obolibrary.org/obo/HP_0031285', 'lbl': 'Abnormal perifollicular morphology', 'desc': 'label: Abnormal perifollicular morphology\ndefinition : Any structural anomaly in the areas surrounding the hair follicles.\nsynonyms :\n'}


{'id': 'HP_0031286', 'url': 'http://purl.obolibrary.org/obo/HP_0031286', 'lbl': 'Perifollicular erythema', 'desc': 'label: Perifollicular erythema\ndefinition : Redness surrounding the hair follicles.\nsynonyms :\n'}


{'id': 'HP_0031287', 'url': 'http://purl.obolibrary.org/obo/HP_0031287', 'lbl': 'Seborrheic keratosis', 'desc': 'label: Seborrheic keratosis\ndefinition : A raised growth on the skin of older individuals. The lesion usually is initially light tan and may darken to dark brown or nearly black. The consistent feature of seborrheic keratoses is their waxy, pasted-on or stuck-on look.\nsynonyms :Basal cell papilloma; Seborrheic verruca; Senile wart\n'}


{'id': 'HP_0031288', 'url': 'http://purl.obolibrary.org/obo/HP_0031288', 'lbl': 'Cobblestone-like hyperkeratosis', 'desc': 'label: Cobblestone-like hyperkeratosis\ndefinition : The presence of verrucous, cobblestone-like papules and nodules in a region of skin that is said to have an appearance like that of cobblestones.\nsynonyms :\n'}


{'id': 'HP_0031289', 'url': 'http://purl.obolibrary.org/obo/HP_0031289', 'lbl': 'White papule', 'desc': 'label: White papule\ndefinition : A papule with white color.\nsynonyms :\n'}


{'id': 'HP_0031290', 'url': 'http://purl.obolibrary.org/obo/HP_0031290', 'lbl': 'Tuberous xanthoma', 'desc': 'label: Tuberous xanthoma\ndefinition : A type of xanthoma characterized by a nodular form. Tuberous xanthomas are firm subcutaneous nodules,whereby the overlying skin can have red or red-yellow color changes.\nsynonyms :\n'}


{'id': 'HP_0031291', 'url': 'http://purl.obolibrary.org/obo/HP_0031291', 'lbl': 'Ichthyosis follicularis', 'desc': 'label: Ichthyosis follicularis\ndefinition : Ichthyosis follicularis is characterized by widespread non inflammatory thorn-like follicular projections. Dyskeratotic papules are most pronounced over the extensor extremities and scalp and are symmetrically distributed.\nsynonyms :\n'}


{'id': 'HP_0031292', 'url': 'http://purl.obolibrary.org/obo/HP_0031292', 'lbl': 'Cutaneous abscess', 'desc': 'label: Cutaneous abscess\ndefinition : A circumscribed area of pus or necrotic debris in the skin.\nsynonyms :Skin abscess\n'}


{'id': 'HP_0031293', 'url': 'http://purl.obolibrary.org/obo/HP_0031293', 'lbl': 'Digital pitting scar', 'desc': 'label: Digital pitting scar\ndefinition : Pinhole-sized concave depressions with hyperkeratosis in the skin of a finger or toe.\nsynonyms :\n'}


{'id': 'HP_0031294', 'url': 'http://purl.obolibrary.org/obo/HP_0031294', 'lbl': 'Hypoplastic right atrium', 'desc': 'label: Hypoplastic right atrium\ndefinition : Underdeveloped, small right heart atrium.\nsynonyms :\n'}


{'id': 'HP_0031295', 'url': 'http://purl.obolibrary.org/obo/HP_0031295', 'lbl': 'Left atrial enlargement', 'desc': 'label: Left atrial enlargement\ndefinition : Increase in size of the left atrium.\nsynonyms :Enlarged heart left atrium\n'}


{'id': 'HP_0031296', 'url': 'http://purl.obolibrary.org/obo/HP_0031296', 'lbl': 'Atrial septal hypertrophy', 'desc': 'label: Atrial septal hypertrophy\ndefinition : An abnormal increase in the thickness of the atrial septum.\nsynonyms :\n'}


{'id': 'HP_0031297', 'url': 'http://purl.obolibrary.org/obo/HP_0031297', 'lbl': 'Unroofed coronary sinus', 'desc': 'label: Unroofed coronary sinus\ndefinition : Unroofed coronary sinus (CS) is a rare congenital cardiac anomaly in which there is partial (either focal or fenestrated) or complete absence of the roof of the CS, which results in a communication between the CS and the LA. Unroofed CS is the rarest type of atrial septal defect. It is often associated with persistent left superior vena cava (LSVC) and other forms of complex congenital heart disease, usually heterotaxia syndromes. The morphological types have been classified into 4 groups: Type I, completely unroofed with persistent LSVC; type II, completely unroofed without persistent LSVC; type III, partially unroofed mid portion; and type IV, partially unroofed terminal portion.\nsynonyms :\n'}


{'id': 'HP_0031298', 'url': 'http://purl.obolibrary.org/obo/HP_0031298', 'lbl': 'Coronary sinus enlargement', 'desc': 'label: Coronary sinus enlargement\ndefinition : Abnormal increase in size of the coronary sinus.\nsynonyms :Coronary sinus dilatation; Enlarged coronary sinus\n'}


{'id': 'HP_0031299', 'url': 'http://purl.obolibrary.org/obo/HP_0031299', 'lbl': 'Elevated left atrial pressure', 'desc': 'label: Elevated left atrial pressure\ndefinition : An abnormal increase in magnitude of the pressure in the left atrium.\nsynonyms :\n'}


{'id': 'HP_0031300', 'url': 'http://purl.obolibrary.org/obo/HP_0031300', 'lbl': 'Abnormal circulating properdin level', 'desc': 'label: Abnormal circulating properdin level\ndefinition : A deviation from the normal concentration of properdin in the blood.\nsynonyms :\n'}


{'id': 'HP_0031301', 'url': 'http://purl.obolibrary.org/obo/HP_0031301', 'lbl': 'Peripheral arterial calcification', 'desc': 'label: Peripheral arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall.\nsynonyms :Peripheral artery calcification\n'}


{'id': 'HP_0031302', 'url': 'http://purl.obolibrary.org/obo/HP_0031302', 'lbl': 'Lower extremity peripheral arterial calcification', 'desc': 'label: Lower extremity peripheral arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the leg.\nsynonyms :Lower extremity peripheral artery calcification\n'}


{'id': 'HP_0031303', 'url': 'http://purl.obolibrary.org/obo/HP_0031303', 'lbl': 'Femoral arterial calcification', 'desc': 'label: Femoral arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the femoral artery.\nsynonyms :\n'}


{'id': 'HP_0031304', 'url': 'http://purl.obolibrary.org/obo/HP_0031304', 'lbl': 'Iliac arterial calcification', 'desc': 'label: Iliac arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the iliac artery.\nsynonyms :\n'}


{'id': 'HP_0031305', 'url': 'http://purl.obolibrary.org/obo/HP_0031305', 'lbl': 'Tibial arterial calcification', 'desc': 'label: Tibial arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the tibial artery.\nsynonyms :\n'}


{'id': 'HP_0031306', 'url': 'http://purl.obolibrary.org/obo/HP_0031306', 'lbl': 'Intracranial arterial calcification', 'desc': 'label: Intracranial arterial calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in an artery that is located within the skull (intracranial).\nsynonyms :\n'}


{'id': 'HP_0031307', 'url': 'http://purl.obolibrary.org/obo/HP_0031307', 'lbl': 'Internal carotid artery calcification', 'desc': 'label: Internal carotid artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the internal carotid artery.\nsynonyms :\n'}


{'id': 'HP_0031308', 'url': 'http://purl.obolibrary.org/obo/HP_0031308', 'lbl': 'Vertebral artery calcification', 'desc': 'label: Vertebral artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the vertebral artery.\nsynonyms :\n'}


{'id': 'HP_0031309', 'url': 'http://purl.obolibrary.org/obo/HP_0031309', 'lbl': 'Cerebral artery calcification', 'desc': 'label: Cerebral artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in a cerebral artery.\nsynonyms :\n'}


{'id': 'HP_0031310', 'url': 'http://purl.obolibrary.org/obo/HP_0031310', 'lbl': 'Basilar artery calcification', 'desc': 'label: Basilar artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the basilar artery.\nsynonyms :\n'}


{'id': 'HP_0031311', 'url': 'http://purl.obolibrary.org/obo/HP_0031311', 'lbl': 'Middle cerebral artery calcification', 'desc': 'label: Middle cerebral artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the middle cerebral artery.\nsynonyms :\n'}


{'id': 'HP_0031313', 'url': 'http://purl.obolibrary.org/obo/HP_0031313', 'lbl': 'Abdominal aortic calcification', 'desc': 'label: Abdominal aortic calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in abdominal aorta.\nsynonyms :\n'}


{'id': 'HP_0031314', 'url': 'http://purl.obolibrary.org/obo/HP_0031314', 'lbl': 'Carotid artery calcification', 'desc': 'label: Carotid artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in a carotid artery.\nsynonyms :\n'}


{'id': 'HP_0031315', 'url': 'http://purl.obolibrary.org/obo/HP_0031315', 'lbl': 'External carotid artery calcification', 'desc': 'label: External carotid artery calcification\ndefinition : An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in the external carotid artery.\nsynonyms :\n'}


{'id': 'HP_0031316', 'url': 'http://purl.obolibrary.org/obo/HP_0031316', 'lbl': 'Abnormal ventricular myocardium morphology', 'desc': 'label: Abnormal ventricular myocardium morphology\ndefinition : A structural anomaly of the muscle layer of the heart wall of a cardiac ventricle.\nsynonyms :\n'}


{'id': 'HP_0031317', 'url': 'http://purl.obolibrary.org/obo/HP_0031317', 'lbl': 'Fatty replacement of ventricular myocardial tissue', 'desc': 'label: Fatty replacement of ventricular myocardial tissue\ndefinition : Presence of an increased amount of fat tissue within a cardiac ventricle with corresponding reduction of muscle tissue.\nsynonyms :Fatty infiltration of cardiac ventricle; Intramyocardial fat infiltration\n'}


{'id': 'HP_0031318', 'url': 'http://purl.obolibrary.org/obo/HP_0031318', 'lbl': 'Myofiber disarray', 'desc': 'label: Myofiber disarray\ndefinition : A nonparallel arrangement of cardiac myocytes.\nsynonyms :Myocardial fiber disarray; Myocardial fibre disarray\n'}


{'id': 'HP_0031319', 'url': 'http://purl.obolibrary.org/obo/HP_0031319', 'lbl': 'Cardiomyocyte hypertrophy', 'desc': 'label: Cardiomyocyte hypertrophy\ndefinition : An increase in cell size, enhanced protein synthesis, and heightened organization of the sarcomere within cardiac myocytes.\nsynonyms :Myocyte cellular hypertrophy\n'}


{'id': 'HP_0031320', 'url': 'http://purl.obolibrary.org/obo/HP_0031320', 'lbl': 'Cardiomyocyte mitochondrial proliferation', 'desc': 'label: Cardiomyocyte mitochondrial proliferation\ndefinition : An abnormal increase in the number of mitochondria per cardiac myocyte.\nsynonyms :\n'}


{'id': 'HP_0031321', 'url': 'http://purl.obolibrary.org/obo/HP_0031321', 'lbl': 'Myocardial immune cell infiltration', 'desc': 'label: Myocardial immune cell infiltration\ndefinition : An increase in the number of immune cells in myocardial tissue (which can be assumed to have migrated into the myocardium).\nsynonyms :\n'}


{'id': 'HP_0031322', 'url': 'http://purl.obolibrary.org/obo/HP_0031322', 'lbl': 'Myocardial lymphocytic infiltration', 'desc': 'label: Myocardial lymphocytic infiltration\ndefinition : An increase in the number of lymphocytes in myocardial tissue.\nsynonyms :\n'}


{'id': 'HP_0031323', 'url': 'http://purl.obolibrary.org/obo/HP_0031323', 'lbl': 'Myocardial eosinophilic infiltration', 'desc': 'label: Myocardial eosinophilic infiltration\ndefinition : An increase in the number of eosinophils in myocardial tissue.\nsynonyms :\n'}


{'id': 'HP_0031324', 'url': 'http://purl.obolibrary.org/obo/HP_0031324', 'lbl': 'Myocardial multinucleated giant cells', 'desc': 'label: Myocardial multinucleated giant cells\ndefinition : The presence of extremely large cells with multiple nuclei. The so-called giant cells are thought to be of macrophage origin.\nsynonyms :\n'}


{'id': 'HP_0031325', 'url': 'http://purl.obolibrary.org/obo/HP_0031325', 'lbl': 'Myocardial granulomatous infiltrates', 'desc': 'label: Myocardial granulomatous infiltrates\ndefinition : The presence of multiple granulomata (small nodular inflammatory lesions containing grouped mononuclear phagocytes) in the myocardium.\nsynonyms :\n'}


{'id': 'HP_0031326', 'url': 'http://purl.obolibrary.org/obo/HP_0031326', 'lbl': 'Monoclonal light chain cardiac amyloidosis', 'desc': 'label: Monoclonal light chain cardiac amyloidosis\ndefinition : A type of cardiac amyloidosis related to deposition of an immunoglobulin light chain. The current gold standard of amyloid typing is to determine the precursor protein using laser microdissection mass spectrometry.\nsynonyms :\n'}


{'id': 'HP_0031327', 'url': 'http://purl.obolibrary.org/obo/HP_0031327', 'lbl': 'Transthyretin cardiac amyloidosis', 'desc': 'label: Transthyretin cardiac amyloidosis\ndefinition : A type of cardiac amyloidosis related to deposition of transthyretin (TTR), which is identified by immunohistochemical staining.\nsynonyms :TTR cardiac amyloidosis\n'}


{'id': 'HP_0031328', 'url': 'http://purl.obolibrary.org/obo/HP_0031328', 'lbl': 'Perivascular cardiac fibrosis', 'desc': 'label: Perivascular cardiac fibrosis\ndefinition : A type of myocardial fibrosis characterized by excessive diffuse collagen accumulation concentrated in perivascular spaces.\nsynonyms :\n'}


{'id': 'HP_0031329', 'url': 'http://purl.obolibrary.org/obo/HP_0031329', 'lbl': 'Interstitial cardiac fibrosis', 'desc': 'label: Interstitial cardiac fibrosis\ndefinition : A type of myocardial fibrosis characterized by excessive diffuse collagen accumulation concentrated in interstitial spaces.\nsynonyms :\n'}


{'id': 'HP_0031330', 'url': 'http://purl.obolibrary.org/obo/HP_0031330', 'lbl': 'Perivascular myocardial immune cell infiltration', 'desc': 'label: Perivascular myocardial immune cell infiltration\ndefinition : An increase in the number of immune cells in myocardial tissue concentrated in the spaces surrounding blood vessels.\nsynonyms :\n'}


{'id': 'HP_0031331', 'url': 'http://purl.obolibrary.org/obo/HP_0031331', 'lbl': 'Abnormal cardiomyocyte morphology', 'desc': 'label: Abnormal cardiomyocyte morphology\ndefinition : Any structural anomaly of cardiomyocytes, which are terminally differentiated muscle cells in the heart that are interconnected end to end by gap junctions, which allows coordinated contraction of heart tissue.\nsynonyms :Abnormal cardiac muscle cell morphology\n'}


{'id': 'HP_0031332', 'url': 'http://purl.obolibrary.org/obo/HP_0031332', 'lbl': 'Cardiomyocyte degeneration', 'desc': 'label: Cardiomyocyte degeneration\ndefinition : Deterioration of cardiomyocyte characterized by abnormal features such as loss of myofilaments, occurrence of cellular sequestration, decreased mitochondrial sizes and cellular debris.\nsynonyms :\n'}


{'id': 'HP_0031333', 'url': 'http://purl.obolibrary.org/obo/HP_0031333', 'lbl': 'Myocardial sarcomeric disarray', 'desc': 'label: Myocardial sarcomeric disarray\ndefinition : A disruption of the structure of the sarcomeres of cardiomyocytes. The sarcomere is the repeating unit between two Z lines comprised largely of myosin and actin that mediates contractility, and normally sarcomeres are aligned with the long axis of cells, with the Z bands being in register throughout the length of the cardiac myocytes.\nsynonyms :Cardiac biopsy: myocyte disarray; Cardiomyocyte disarray; Myocardial sarcomere disarray\n'}


{'id': 'HP_0031334', 'url': 'http://purl.obolibrary.org/obo/HP_0031334', 'lbl': 'Cardiomyocyte inclusion bodies', 'desc': 'label: Cardiomyocyte inclusion bodies\ndefinition : Nuclear or cytoplasmic aggregates of stainable substances within cardiomyocytes.\nsynonyms :\n'}


{'id': 'HP_0031335', 'url': 'http://purl.obolibrary.org/obo/HP_0031335', 'lbl': 'Abnormal cardiomyocyte mitochondrial morphology', 'desc': 'label: Abnormal cardiomyocyte mitochondrial morphology\ndefinition : An anomaly of the structure of mitochondria within cardiomyocytes.\nsynonyms :\n'}


{'id': 'HP_0031336', 'url': 'http://purl.obolibrary.org/obo/HP_0031336', 'lbl': 'Intranuclear cardiomyocyte mitochondria', 'desc': 'label: Intranuclear cardiomyocyte mitochondria\ndefinition : Abnormal localization of mitochondria within the nuclei of cardiomyocytes.\nsynonyms :\n'}


{'id': 'HP_0031337', 'url': 'http://purl.obolibrary.org/obo/HP_0031337', 'lbl': 'Abnormal cardiomyocyte connexin43 staining', 'desc': 'label: Abnormal cardiomyocyte connexin43 staining\ndefinition : Anomalous staining of Connexin43 in cardiomyocytes. Connexin43 (Cx43) is the primary gap junction protein in the working myocardium. Cx43 exhibits increased localization at the lateral membranes of cardiomyocytes in a variety of heart diseases.\nsynonyms :\n'}


{'id': 'HP_0031338', 'url': 'http://purl.obolibrary.org/obo/HP_0031338', 'lbl': 'Abnormal cardiomyocyte plakoglobin staining', 'desc': 'label: Abnormal cardiomyocyte plakoglobin staining\ndefinition : Anomalous staining of plakoglobin in cardiomyocytes. Plakoglobin is a component of desmosomes in cardiomyocytes.\nsynonyms :\n'}


{'id': 'HP_0031339', 'url': 'http://purl.obolibrary.org/obo/HP_0031339', 'lbl': 'Abnormal cardiomyocyte dystrophin staining', 'desc': 'label: Abnormal cardiomyocyte dystrophin staining\ndefinition : Anomalous staining of dystrophin in cardiomyocytes.\nsynonyms :\n'}


{'id': 'HP_0031340', 'url': 'http://purl.obolibrary.org/obo/HP_0031340', 'lbl': 'Abnormal lysosomal morphology', 'desc': 'label: Abnormal lysosomal morphology\ndefinition : A structural anomaly of lysosomes, membrane-enclosed organelles that contain an array of enzymes capable of catabolizing proteins, nucleic acids, carbohydrates, and lipids.\nsynonyms :\n'}


{'id': 'HP_0031341', 'url': 'http://purl.obolibrary.org/obo/HP_0031341', 'lbl': 'Gastric arteriovenous malformation', 'desc': 'label: Gastric arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the stomach.\nsynonyms :\n'}


{'id': 'HP_0031342', 'url': 'http://purl.obolibrary.org/obo/HP_0031342', 'lbl': 'Duodenal arteriovenous malformation', 'desc': 'label: Duodenal arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the duodenum.\nsynonyms :\n'}


{'id': 'HP_0031343', 'url': 'http://purl.obolibrary.org/obo/HP_0031343', 'lbl': 'Jejunal arteriovenous malformation', 'desc': 'label: Jejunal arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the jejunum.\nsynonyms :\n'}


{'id': 'HP_0031344', 'url': 'http://purl.obolibrary.org/obo/HP_0031344', 'lbl': 'Pelvic arteriovenous malformation', 'desc': 'label: Pelvic arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the pelvis.\nsynonyms :\n'}


{'id': 'HP_0031345', 'url': 'http://purl.obolibrary.org/obo/HP_0031345', 'lbl': 'Colonic arteriovenous malformation', 'desc': 'label: Colonic arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the colon.\nsynonyms :\n'}


{'id': 'HP_0031346', 'url': 'http://purl.obolibrary.org/obo/HP_0031346', 'lbl': 'Rectal arteriovenous malformation', 'desc': 'label: Rectal arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the rectum.\nsynonyms :\n'}


{'id': 'HP_0031347', 'url': 'http://purl.obolibrary.org/obo/HP_0031347', 'lbl': 'Uterine arteriovenous malformation', 'desc': 'label: Uterine arteriovenous malformation\ndefinition : An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries and that is located in the uterus.\nsynonyms :\n'}


{'id': 'HP_0031348', 'url': 'http://purl.obolibrary.org/obo/HP_0031348', 'lbl': 'Dextrotransposition of the great arteries', 'desc': 'label: Dextrotransposition of the great arteries\ndefinition : A type of transposition of the great arteries (TGA) in which aorta is in front of and primarily to the right of the pulmonary artery. This is the most common kind of TGA.\nsynonyms :D-TGA; D-loop transposition of the great arteries\n'}


{'id': 'HP_0031349', 'url': 'http://purl.obolibrary.org/obo/HP_0031349', 'lbl': 'Levotransposition of the great arteries', 'desc': 'label: Levotransposition of the great arteries\ndefinition : A type of transposition of the great arteries (TGA) in which aorta is in front of and primarily to the left of the pulmonary artery.\nsynonyms :L-TGA\n'}


{'id': 'HP_0031350', 'url': 'http://purl.obolibrary.org/obo/HP_0031350', 'lbl': 'Cardiac sarcoma', 'desc': 'label: Cardiac sarcoma\ndefinition : A malignant soft tissue neoplasm that arises from the heart.\nsynonyms :\n'}


{'id': 'HP_0031351', 'url': 'http://purl.obolibrary.org/obo/HP_0031351', 'lbl': 'Calcified amorphous tumor of the heart', 'desc': 'label: Calcified amorphous tumor of the heart\ndefinition : A non-neoplastic cardiac tumor characterized by calcification and eosinophilic amorphous material in the background of dense collagenous fibrous tissue.\nsynonyms :Calcified amorphous tumour of the heart\n'}


{'id': 'HP_0031352', 'url': 'http://purl.obolibrary.org/obo/HP_0031352', 'lbl': 'Chest tightness', 'desc': 'label: Chest tightness\ndefinition : An unpleasant sensation of tightness or pressure in the chest.\nsynonyms :Tightness in chest; Tightness of chest; Chest distress\n'}


{'id': 'HP_0031353', 'url': 'http://purl.obolibrary.org/obo/HP_0031353', 'lbl': 'Otitis media with effusion', 'desc': 'label: Otitis media with effusion\ndefinition : Otitis media characterized by thick or sticky fluid behind the tympanic membrane.\nsynonyms :Fluid behind eardrum\n'}


{'id': 'HP_0031354', 'url': 'http://purl.obolibrary.org/obo/HP_0031354', 'lbl': 'Sleep onset insomnia', 'desc': 'label: Sleep onset insomnia\ndefinition : Difficulty initiating sleep, that is, increased sleep onset latency.\nsynonyms :Difficulty falling asleep\n'}


{'id': 'HP_0031355', 'url': 'http://purl.obolibrary.org/obo/HP_0031355', 'lbl': 'Maintenance insomnia', 'desc': 'label: Maintenance insomnia\ndefinition : Abnormal difficulty in staying asleep. Affected individuals tend to wake up at night and have difficulty returning to sleep.\nsynonyms :Waking up several times during the night\n'}


{'id': 'HP_0031356', 'url': 'http://purl.obolibrary.org/obo/HP_0031356', 'lbl': 'Terminal insomnia', 'desc': 'label: Terminal insomnia\ndefinition : A type of insomnia characterized by waking up (too) early in the morning.\nsynonyms :Late insomnia\n'}


{'id': 'HP_0031357', 'url': 'http://purl.obolibrary.org/obo/HP_0031357', 'lbl': 'Glomeruloid hemangioma', 'desc': 'label: Glomeruloid hemangioma\ndefinition : A histologically distinctive, cutaneous, benign vascular tumor that is characterized by a solitary or multiple blue-red papules and histologically resembles renal glomeruli.\nsynonyms :\n'}


{'id': 'HP_0031358', 'url': 'http://purl.obolibrary.org/obo/HP_0031358', 'lbl': 'Vegetative state', 'desc': 'label: Vegetative state\ndefinition : Absence of wakefulness and conscience, but (in contrast to coma) with involuntary opening of the eyes and movements (such as teeth grinding, yawning, or thrashing of the extremities).\nsynonyms :\n'}


{'id': 'HP_0031359', 'url': 'http://purl.obolibrary.org/obo/HP_0031359', 'lbl': 'Cutaneous sclerotic plaque', 'desc': 'label: Cutaneous sclerotic plaque\ndefinition : A solid, raised, plateau-like (flat-topped) lesion greater than 1 cm in diameter that is characterized by hardening (sclerosis) of the affected skin area (related to collagen thickening).\nsynonyms :\n'}


{'id': 'HP_0031360', 'url': 'http://purl.obolibrary.org/obo/HP_0031360', 'lbl': 'Yellow skin plaque', 'desc': 'label: Yellow skin plaque\ndefinition : A solid, raised, plateau-like (flat-topped) lesion greater than 1 cm in diameter and that has a yellow color.\nsynonyms :\n'}


{'id': 'HP_0031361', 'url': 'http://purl.obolibrary.org/obo/HP_0031361', 'lbl': 'Zebra bodies', 'desc': 'label: Zebra bodies\ndefinition : Intralysosomal, osmiophilic, lamellated and sometimes concentric cytoplasmic inclusions comprised of broad transversely-stacked myelinoid membranes and said to resemble a zebra in electron microscopic images.\nsynonyms :\n'}


{'id': 'HP_0031362', 'url': 'http://purl.obolibrary.org/obo/HP_0031362', 'lbl': 'obsolete Sex-limited autosomal recessive inheritance', 'desc': 'label: obsolete Sex-limited autosomal recessive inheritance\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031363', 'url': 'http://purl.obolibrary.org/obo/HP_0031363', 'lbl': 'Palpable purpura', 'desc': 'label: Palpable purpura\ndefinition : A type of purpura in which the lesions are raised (and can therefore be appreciated upon palpation).\nsynonyms :\n'}


{'id': 'HP_0031364', 'url': 'http://purl.obolibrary.org/obo/HP_0031364', 'lbl': 'Ecchymosis', 'desc': 'label: Ecchymosis\ndefinition : A purpuric lesion that is larger than 1 cm in diameter.\nsynonyms :Ecchymoses\n'}


{'id': 'HP_0031365', 'url': 'http://purl.obolibrary.org/obo/HP_0031365', 'lbl': 'Macular purpura', 'desc': 'label: Macular purpura\ndefinition : Purpura that is flat (non-palpable, not raised).\nsynonyms :Flat purpura\n'}


{'id': 'HP_0031366', 'url': 'http://purl.obolibrary.org/obo/HP_0031366', 'lbl': 'Palate neoplasm', 'desc': 'label: Palate neoplasm\ndefinition : A neoplasm that affects the hard palate, soft palate, or uvula.\nsynonyms :\n'}


{'id': 'HP_0031367', 'url': 'http://purl.obolibrary.org/obo/HP_0031367', 'lbl': 'Metaphyseal striations', 'desc': 'label: Metaphyseal striations\ndefinition : Longitudinal densities on radiographs located in a metaphysis (the narrow region of a long bone between the epiphysis and the diaphysis).\nsynonyms :Striated metaphysis\n'}


{'id': 'HP_0031368', 'url': 'http://purl.obolibrary.org/obo/HP_0031368', 'lbl': 'Intestinal perforation', 'desc': 'label: Intestinal perforation\ndefinition : A hole (perforation) in the wall of the intestine.\nsynonyms :\n'}


{'id': 'HP_0031369', 'url': 'http://purl.obolibrary.org/obo/HP_0031369', 'lbl': 'Colon perforation', 'desc': 'label: Colon perforation\ndefinition : A hole (perforation) in the wall of the colon.\nsynonyms :Perforation of the colon\n'}


{'id': 'HP_0031370', 'url': 'http://purl.obolibrary.org/obo/HP_0031370', 'lbl': 'Small intestinal perforation', 'desc': 'label: Small intestinal perforation\ndefinition : A hole (perforation) in the wall of the small intestine.\nsynonyms :\n'}


{'id': 'HP_0031371', 'url': 'http://purl.obolibrary.org/obo/HP_0031371', 'lbl': 'Rectal perforation', 'desc': 'label: Rectal perforation\ndefinition : A hole (perforation) in the wall of the rectum.\nsynonyms :\n'}


{'id': 'HP_0031372', 'url': 'http://purl.obolibrary.org/obo/HP_0031372', 'lbl': 'Cold paresis', 'desc': 'label: Cold paresis\ndefinition : Increased muscle weakness upon exposure to cold temperatures.\nsynonyms :\n'}


{'id': 'HP_0031373', 'url': 'http://purl.obolibrary.org/obo/HP_0031373', 'lbl': 'Stiff tongue', 'desc': 'label: Stiff tongue\ndefinition : Increased rigidity and reduced mobility of the tongue.\nsynonyms :Tongue stiffness\n'}


{'id': 'HP_0031374', 'url': 'http://purl.obolibrary.org/obo/HP_0031374', 'lbl': 'Ankle weakness', 'desc': 'label: Ankle weakness\ndefinition : Reduced strength of the muscles that lift or otherwise move the foot at the ankle.\nsynonyms :\n'}


{'id': 'HP_0031375', 'url': 'http://purl.obolibrary.org/obo/HP_0031375', 'lbl': 'Refractory', 'desc': 'label: Refractory\ndefinition : Applies to a sign or symptom that is difficult to treat or cure.\nsynonyms :\n'}


{'id': 'HP_0031377', 'url': 'http://purl.obolibrary.org/obo/HP_0031377', 'lbl': 'Abnormal cell proliferation', 'desc': 'label: Abnormal cell proliferation\ndefinition : Any abnormality in the multiplication or reproduction of cells, which may result in the expansion of a cell population.\nsynonyms :\n'}


{'id': 'HP_0031378', 'url': 'http://purl.obolibrary.org/obo/HP_0031378', 'lbl': 'Abnormal lymphocyte proliferation', 'desc': 'label: Abnormal lymphocyte proliferation\ndefinition : Any abnormality in the multiplication or reproduction of lymphocytes, which results in the expansion of a cell population.\nsynonyms :\n'}


{'id': 'HP_0031379', 'url': 'http://purl.obolibrary.org/obo/HP_0031379', 'lbl': 'Abnormal T cell proliferation', 'desc': 'label: Abnormal T cell proliferation\ndefinition : Any abnormality in the multiplication or reproduction of T cells, which results in the expansion of a cell population.\nsynonyms :\n'}


{'id': 'HP_0031380', 'url': 'http://purl.obolibrary.org/obo/HP_0031380', 'lbl': 'Abnormal B cell proliferation', 'desc': 'label: Abnormal B cell proliferation\ndefinition : Any abnormality in the multiplication or reproduction of B cells, which results in the expansion of a cell population.\nsynonyms :\n'}


{'id': 'HP_0031381', 'url': 'http://purl.obolibrary.org/obo/HP_0031381', 'lbl': 'Decreased lymphocyte proliferation in response to mitogen', 'desc': 'label: Decreased lymphocyte proliferation in response to mitogen\ndefinition : A decreased proliferative response of lymphocytes in vitro or in vivo, when stimulated with mitogens, such as phytohemagglutinin (PHA).\nsynonyms :Reduced lymphocyte proliferation to mitogen\n'}


{'id': 'HP_0031382', 'url': 'http://purl.obolibrary.org/obo/HP_0031382', 'lbl': 'Decreased lymphocyte proliferation in response to anti-CD3', 'desc': 'label: Decreased lymphocyte proliferation in response to anti-CD3\ndefinition : A decreased proliferative response of lymphocytes in vitro or in vivo, when stimulated with an anti-CD3 antibody against the T-cell co-receptor, CD3.\nsynonyms :Defective lymphocyte proliferation to anti-CD3; Defective proliferation of lymphocytes following anti-CD3 stimulation\n'}


{'id': 'HP_0031383', 'url': 'http://purl.obolibrary.org/obo/HP_0031383', 'lbl': 'Abnormal lymphocyte surface marker expression', 'desc': 'label: Abnormal lymphocyte surface marker expression\ndefinition : Abnormal amount of a protein that is normally present on the cell surface of lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0031384', 'url': 'http://purl.obolibrary.org/obo/HP_0031384', 'lbl': 'Reduced T cell CD40 expression', 'desc': 'label: Reduced T cell CD40 expression\ndefinition : A deficiency in the expression of the CD40 ligand on the surface of activated T-lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0031385', 'url': 'http://purl.obolibrary.org/obo/HP_0031385', 'lbl': 'Megakaryocyte nucleus hypolobulation', 'desc': 'label: Megakaryocyte nucleus hypolobulation\ndefinition : The presence of megakaryocytes in the bone marrow whose nuclei are less lobulated than expected for the size of the nucleus.\nsynonyms :\n'}


{'id': 'HP_0031386', 'url': 'http://purl.obolibrary.org/obo/HP_0031386', 'lbl': 'Increased micromegakaryocyte count', 'desc': 'label: Increased micromegakaryocyte count\ndefinition : The presence of abnormally high numbers of micromegakaryocytes in the bone marrow. Micromegakaryocytes are mononuclear diploid cells, with a nucleus similar in size to that of a myeloblast or promyelocyte with the cell being less than 30 micrometers in diameter.\nsynonyms :\n'}


{'id': 'HP_0031387', 'url': 'http://purl.obolibrary.org/obo/HP_0031387', 'lbl': 'Increased multinucleated megakaryocyte count', 'desc': 'label: Increased multinucleated megakaryocyte count\ndefinition : The presence of abnormally high numbers of multinucleated megakaryocytes in the bone marrow.\nsynonyms :\n'}


{'id': 'HP_0031388', 'url': 'http://purl.obolibrary.org/obo/HP_0031388', 'lbl': 'Megakaryocyte nucleus hyperlobulation', 'desc': 'label: Megakaryocyte nucleus hyperlobulation\ndefinition : The presence of megakaryocytes in the bone marrow whose nuclei are more lobulated than expected for the size of the nucleus.\nsynonyms :\n'}


{'id': 'HP_0031389', 'url': 'http://purl.obolibrary.org/obo/HP_0031389', 'lbl': 'Abnormal MHC II surface expression', 'desc': 'label: Abnormal MHC II surface expression\ndefinition : A deviation from the normal level of major histocompatibility complex class II molecules expressed at the cell surface.\nsynonyms :\n'}


{'id': 'HP_0031390', 'url': 'http://purl.obolibrary.org/obo/HP_0031390', 'lbl': 'Reduced MHC II surface expression', 'desc': 'label: Reduced MHC II surface expression\ndefinition : A reduction from the normal level of major histocompatibility complex class II molecules expressed at the cell surface.\nsynonyms :\n'}


{'id': 'HP_0031391', 'url': 'http://purl.obolibrary.org/obo/HP_0031391', 'lbl': 'Elevated MHC II surface expression', 'desc': 'label: Elevated MHC II surface expression\ndefinition : An increase above the normal level of major histocompatibility complex class II molecules expressed at the cell surface.\nsynonyms :\n'}


{'id': 'HP_0031392', 'url': 'http://purl.obolibrary.org/obo/HP_0031392', 'lbl': 'Abnormal proportion of CD4-positive T cells', 'desc': 'label: Abnormal proportion of CD4-positive T cells\ndefinition : Any abnormality in the proportion of CD4-positive T cells relative to the total number of T cells.\nsynonyms :Abnormal proportion of CD4+ T cells; Abnormal proportion of CD4-positive, alpha-beta T cells\n'}


{'id': 'HP_0031393', 'url': 'http://purl.obolibrary.org/obo/HP_0031393', 'lbl': 'Abnormal proportion of CD8-positive T cells', 'desc': 'label: Abnormal proportion of CD8-positive T cells\ndefinition : Any abnormality in the proportion of CD8 T cells relative to the total number of T cells.\nsynonyms :Abnormal proportion of CD8+ T cells; Abnormal proportion of CD8-positive, alpha-beta T cells\n'}


{'id': 'HP_0031394', 'url': 'http://purl.obolibrary.org/obo/HP_0031394', 'lbl': 'Abnormal CD4:CD8 ratio', 'desc': 'label: Abnormal CD4:CD8 ratio\ndefinition : Any abnormality in the relative amount of CD4+ and CD8+ T lymphocytes.\nsynonyms :\n'}


{'id': 'HP_0031396', 'url': 'http://purl.obolibrary.org/obo/HP_0031396', 'lbl': 'Abnormal proportion of naive T cells', 'desc': 'label: Abnormal proportion of naive T cells\ndefinition : Any abnormality in the proportion of naive T cells relative to the total number of T cells.\nsynonyms :Abnormal naive T cell proportion; Abnormal proportion of naive thymus-derived, alpha-beta T cells\n'}


{'id': 'HP_0031397', 'url': 'http://purl.obolibrary.org/obo/HP_0031397', 'lbl': 'Decreased proportion of naive T cells', 'desc': 'label: Decreased proportion of naive T cells\ndefinition : An abnormally decreased proportion of naive T cells relative to the total number of T cells.\nsynonyms :Decreased proportion of naive thymus-derived, alpha-beta T cells; Reduced proportion of naive T cells\n'}


{'id': 'HP_0031398', 'url': 'http://purl.obolibrary.org/obo/HP_0031398', 'lbl': 'Increased proportion of naive T cells', 'desc': 'label: Increased proportion of naive T cells\ndefinition : An abnormally increased proportion of naive T cells relative to the total number of T cells.\nsynonyms :Elevated proportion of naive T cells; Increased proportion of naive thymus-derived, alpha-beta T cells\n'}


{'id': 'HP_0031399', 'url': 'http://purl.obolibrary.org/obo/HP_0031399', 'lbl': 'Abnormal proportion of double-negative alpha-beta regulatory T cell', 'desc': 'label: Abnormal proportion of double-negative alpha-beta regulatory T cell\ndefinition : An abnormal proportion of CD4-negative, CD8-negative (double negative or DN) alpha-beta regulatory T cells (Tregs) as compared to total number of T cells.\nsynonyms :Abnormal CD4-negative, CD8-negative, alpha-beta regulatory T cell distribution; Abnormal DN Treg distribution; Abnormal Double negative Treg distribution; Abnormal double-negative alpha-beta regulatory T cell distribution\n'}


{'id': 'HP_0031401', 'url': 'http://purl.obolibrary.org/obo/HP_0031401', 'lbl': 'Reduced proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells', 'desc': 'label: Reduced proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells\ndefinition : An abnormally decreased proportion of CD4-negative, CD8-negative (double negative or DN) alpha-beta regulatory T cells (Tregs) as compared to total number of T cells.\nsynonyms :\n'}


{'id': 'HP_0031402', 'url': 'http://purl.obolibrary.org/obo/HP_0031402', 'lbl': 'Reduced antigen-specific T cell proliferation', 'desc': 'label: Reduced antigen-specific T cell proliferation\ndefinition : Impaired proliferation and expansion of a T cell population following activation by an antigenic stimulus.\nsynonyms :Impaired cellular adaptive immune response; Antigen-specific T cell proliferation defect; Impaired Ag-specific T cell proliferation; Impaired activated T cell proliferation\n'}


{'id': 'HP_0031403', 'url': 'http://purl.obolibrary.org/obo/HP_0031403', 'lbl': 'Impaired pathogen-specific CD8 cytoxicity', 'desc': 'label: Impaired pathogen-specific CD8 cytoxicity\ndefinition : Impaired response of CD8 T cells to pathogens. CD8 T cells direct the killing of a target cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.\nsynonyms :Pathogen-specific CD8 cytoxicity defect\n'}


{'id': 'HP_0031404', 'url': 'http://purl.obolibrary.org/obo/HP_0031404', 'lbl': 'Impaired antigen-specific response', 'desc': 'label: Impaired antigen-specific response\ndefinition : An impaired immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).\nsynonyms :Impaired adaptive immune response\n'}


{'id': 'HP_0031405', 'url': 'http://purl.obolibrary.org/obo/HP_0031405', 'lbl': 'Poroma', 'desc': 'label: Poroma\ndefinition : A benign, well circumscribed sweat gland neoplasm with eccrine or apocrine differentiation. It usually presents as a solitary, dome-shaped papule, nodule, or plaque on acral sites. It is characterized by a proliferation of uniform basaloid cells in the dermis and it is associated with the presence of focal ductal and cystic structures [NCIT:C27273].\nsynonyms :\n'}


{'id': 'HP_0031406', 'url': 'http://purl.obolibrary.org/obo/HP_0031406', 'lbl': 'Abnormal cytokine signaling', 'desc': 'label: Abnormal cytokine signaling\ndefinition : Any abnormality in the series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.\nsynonyms :Abnormal cytokine signalling\n'}


{'id': 'HP_0031407', 'url': 'http://purl.obolibrary.org/obo/HP_0031407', 'lbl': 'Impaired cytokine signaling', 'desc': 'label: Impaired cytokine signaling\ndefinition : A defect or impairment in the series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.\nsynonyms :Cytokine signaling defect; Cytokine signalling defect; Impaired cytokine signalling\n'}


{'id': 'HP_0031408', 'url': 'http://purl.obolibrary.org/obo/HP_0031408', 'lbl': 'Increased proportion of CD25+ mast cells', 'desc': 'label: Increased proportion of CD25+ mast cells\ndefinition : An increased proportion of mast cells are positive for the cell surface marker CD25 (also called interleukin-2 receptor alpha chain).\nsynonyms :\n'}


{'id': 'HP_0031409', 'url': 'http://purl.obolibrary.org/obo/HP_0031409', 'lbl': 'Abnormal lymphocyte physiology', 'desc': 'label: Abnormal lymphocyte physiology\ndefinition : Any anomaly of lymphocyte function.\nsynonyms :\n'}


{'id': 'HP_0031410', 'url': 'http://purl.obolibrary.org/obo/HP_0031410', 'lbl': 'Abnormal distribution of CD56 bright/dim natural killer cells', 'desc': 'label: Abnormal distribution of CD56 bright/dim natural killer cells\ndefinition : An abnormal distribution in the number of CD56 bright NK cells, as measured by flow cytometry. CD56, an adhesion molecule mediating homotypic adhesion, is used as a functional marker for NK cells.\nsynonyms :Abnormal distribution of CD56 bright/dim NK cells\n'}


{'id': 'HP_0031411', 'url': 'http://purl.obolibrary.org/obo/HP_0031411', 'lbl': 'Abnormal chromosome morphology', 'desc': 'label: Abnormal chromosome morphology\ndefinition : Any structural anomaly of a chromosome, which is a thread like molecule consisting of DNA and proteins (chromatin) that contains DNA sequences for genes and other genetic elements in linear order.\nsynonyms :\n'}


{'id': 'HP_0031412', 'url': 'http://purl.obolibrary.org/obo/HP_0031412', 'lbl': 'Abnormal telomere morphology', 'desc': 'label: Abnormal telomere morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031413', 'url': 'http://purl.obolibrary.org/obo/HP_0031413', 'lbl': 'Short telomere length', 'desc': 'label: Short telomere length\ndefinition : An abnormal reduction in telomere length. Telomeres are non-coding, repetitive sequences of DNA at the ends of the chromosomes of eukaryotic cells which become shorter as cells divide, and when telomere attrition reaches its limit, cell proliferation arrest, senescence, and apoptosis can occur.\nsynonyms :\n'}


{'id': 'HP_0031414', 'url': 'http://purl.obolibrary.org/obo/HP_0031414', 'lbl': 'High serum calcifediol', 'desc': 'label: High serum calcifediol\ndefinition : An increased concentration of calcifediol in the blood. Calcifediol is also known as 25-hydroxycholecalciferol or 25-Hydroxyvitamin D3.\nsynonyms :High serum 25-hydroxycholecalciferol; High serum calcidiol\n'}


{'id': 'HP_0031415', 'url': 'http://purl.obolibrary.org/obo/HP_0031415', 'lbl': 'High serum calcitriol', 'desc': 'label: High serum calcitriol\ndefinition : An increased concentration of calcitriol in the blood. Calcitriol is also known as 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3.\nsynonyms :High serum 1,25-dihydroxycholecalciferol; High serum 1,25-dihydroxyvitamin D3; Increased serum 1,25-dihydroxyvitamin D3; Increased serum calcitriol\n'}


{'id': 'HP_0031416', 'url': 'http://purl.obolibrary.org/obo/HP_0031416', 'lbl': 'Abnormal nasal mucus secretion', 'desc': 'label: Abnormal nasal mucus secretion\ndefinition : Any deviation from the normal quantity of secretion of nasal mucus, a thick viscous liquid produced by the mucous membranes of the nose.\nsynonyms :\n'}


{'id': 'HP_0031417', 'url': 'http://purl.obolibrary.org/obo/HP_0031417', 'lbl': 'Rhinorrhea', 'desc': 'label: Rhinorrhea\ndefinition : Increased discharge of mucus from the nose.\nsynonyms :Nasal Discharge; Runny Nose\n'}


{'id': 'HP_0031418', 'url': 'http://purl.obolibrary.org/obo/HP_0031418', 'lbl': 'Increased body mass index', 'desc': "label: Increased body mass index\ndefinition : Abnormally increased weight-to-height squared ratio, calculated by dividing the individual's weight in kilograms by the square of the individual's height in meters and used as an indicator of overweight compared to averages.\nsynonyms :Increased BMI\n"}


{'id': 'HP_0031419', 'url': 'http://purl.obolibrary.org/obo/HP_0031419', 'lbl': 'Reduced sex -hormone binding protein level', 'desc': 'label: Reduced sex -hormone binding protein level\ndefinition : A decreased concentration of sex-hormone binding protein in the circulation.\nsynonyms :Reduced androgen-binding protein level\n'}


{'id': 'HP_0031420', 'url': 'http://purl.obolibrary.org/obo/HP_0031420', 'lbl': 'Small yellow foveal lesion with surrounding gray zone', 'desc': 'label: Small yellow foveal lesion with surrounding gray zone\ndefinition : A lesion that is observed following light damage to the macula. Damage to the retinal by exposure to intense visible light, usually the sun. Intense light exposure such as staring at the sun causes fine structural anomalies in the outer segments of the photoreceptors and the retinal pigment epithelium (RPE) cells of the macula. Symptoms usually develop within 1 to 4 h after exposure and include decreased vision, metamorphopsia, micropsia, and central or paracentral scotomas. Fundus examination typically shows a small yellow spot with a surrounding gray zone in the foveolar or parafoveolar area. Spontaneous evolution leads to the improvement of visual acuity.\nsynonyms :Small yellow foveal lesion with surrounding grey zone; Laser pointer-induced maculopathy; Laser pointer-induced retinopathy; Light induced retinopathy; Photic retinopathy; Solar retinitis; Solar retinopathy\n'}


{'id': 'HP_0031421', 'url': 'http://purl.obolibrary.org/obo/HP_0031421', 'lbl': 'Small superior frontal cortex', 'desc': 'label: Small superior frontal cortex\ndefinition : Reduced size of the superior frontal portion of the cerebral cortex.\nsynonyms :\n'}


{'id': 'HP_0031422', 'url': 'http://purl.obolibrary.org/obo/HP_0031422', 'lbl': 'Abnormal cerebellar cortex morphology', 'desc': 'label: Abnormal cerebellar cortex morphology\ndefinition : Any structural anomaly of the cortex of the cerebellum.\nsynonyms :Abnormal morphology of the cerebellar cortex\n'}


{'id': 'HP_0031423', 'url': 'http://purl.obolibrary.org/obo/HP_0031423', 'lbl': 'Small cerebellar cortex', 'desc': 'label: Small cerebellar cortex\ndefinition : Reduced size of the cerebellar cortex.\nsynonyms :\n'}


{'id': 'HP_0031424', 'url': 'http://purl.obolibrary.org/obo/HP_0031424', 'lbl': 'Abnormal circulating beta-C-terminal telopeptide concentration', 'desc': 'label: Abnormal circulating beta-C-terminal telopeptide concentration\ndefinition : A deviation from the normal concentration of beta-C-terminal telopeptide of type I collagen in the blood circulation, a marker of the rate of bone turnover.\nsynonyms :Abnormal circulating beta-C-terminal telopeptide level; Abnormal circulating beta-CTx level; Abnormal circulating beta-CrossLaps level\n'}


{'id': 'HP_0031425', 'url': 'http://purl.obolibrary.org/obo/HP_0031425', 'lbl': 'Increased circulating beta-C-terminal telopeptide concentration', 'desc': 'label: Increased circulating beta-C-terminal telopeptide concentration\ndefinition : A abnormal elevation above the normal concentration of beta-C-terminal telopeptide of type I collagen in the blood circulation.\nsynonyms :Increased circulating beta-C-terminal telopeptide level; Increased circulating beta-CTx level; Increased circulating beta-CrossLaps level\n'}


{'id': 'HP_0031426', 'url': 'http://purl.obolibrary.org/obo/HP_0031426', 'lbl': 'Decreased circulating beta-C-terminal telopeptide concentration', 'desc': 'label: Decreased circulating beta-C-terminal telopeptide concentration\ndefinition : A reduction from the normal concentration of beta-C-terminal telopeptide of type I collagen in the blood circulation.\nsynonyms :Decreased circulating beta-C-terminal telopeptide level; Decreased circulating beta-CTx level; Decreased circulating beta-CrossLaps level\n'}


{'id': 'HP_0031427', 'url': 'http://purl.obolibrary.org/obo/HP_0031427', 'lbl': 'Abnormal circulating osteocalcin level', 'desc': 'label: Abnormal circulating osteocalcin level\ndefinition : A deviation from the normal concentration of osteocalcin in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0031428', 'url': 'http://purl.obolibrary.org/obo/HP_0031428', 'lbl': 'Increased circulating osteocalcin level', 'desc': 'label: Increased circulating osteocalcin level\ndefinition : An elevated level of osteocalcin in the blood.\nsynonyms :\n'}


{'id': 'HP_0031429', 'url': 'http://purl.obolibrary.org/obo/HP_0031429', 'lbl': 'Decreased circulating osteocalcin level', 'desc': 'label: Decreased circulating osteocalcin level\ndefinition : A reduced level of osteocalcin in the blood.\nsynonyms :\n'}


{'id': 'HP_0031430', 'url': 'http://purl.obolibrary.org/obo/HP_0031430', 'lbl': 'Oligoclonal T cell expansion', 'desc': 'label: Oligoclonal T cell expansion\ndefinition : The presence of a population of T cells with a restricted T cell receptor (TCR) repertoire derived from a limited number of TCR clones.\nsynonyms :\n'}


{'id': 'HP_0031431', 'url': 'http://purl.obolibrary.org/obo/HP_0031431', 'lbl': 'Persistent repetition of words or sounds', 'desc': 'label: Persistent repetition of words or sounds\ndefinition : Repetitive use of words, phrases, intonation, or sounds of speech, often of the speech of others.\nsynonyms :\n'}


{'id': 'HP_0031432', 'url': 'http://purl.obolibrary.org/obo/HP_0031432', 'lbl': 'Atypical repetitive behaviors', 'desc': 'label: Atypical repetitive behaviors\ndefinition : A broad range of behaviors that are repeated including simple motor stereotypies and tics as well as more complex repetitive movements or compulsions.\nsynonyms :\n'}


{'id': 'HP_0031433', 'url': 'http://purl.obolibrary.org/obo/HP_0031433', 'lbl': 'Alexithymia', 'desc': "label: Alexithymia\ndefinition : A deficit in emotional awareness characterized by difficulties in recognizing and expressing feelings and emotions manifested as a limited ability to respond to facial clues or other signs of emotions in others often accompanied by detached connections to others.\nsynonyms :Unaware of others' emotions\n"}


{'id': 'HP_0031434', 'url': 'http://purl.obolibrary.org/obo/HP_0031434', 'lbl': 'Abnormal prosody', 'desc': 'label: Abnormal prosody\ndefinition : Abnormalities in the patterns of stress or intonation of speech or vocalization.\nsynonyms :\n'}


{'id': 'HP_0031435', 'url': 'http://purl.obolibrary.org/obo/HP_0031435', 'lbl': 'Monotonic speech', 'desc': 'label: Monotonic speech\ndefinition : A speech pattern characterized by abnormally reduced or lacking variability of the pitch of the voice.\nsynonyms :\n'}


{'id': 'HP_0031436', 'url': 'http://purl.obolibrary.org/obo/HP_0031436', 'lbl': 'Singsong Intonation', 'desc': 'label: Singsong Intonation\ndefinition : A speech pattern characterized by abnormal fluctuations in the pitch of the voice.\nsynonyms :\n'}


{'id': 'HP_0031437', 'url': 'http://purl.obolibrary.org/obo/HP_0031437', 'lbl': 'Pregnancy exposure', 'desc': 'label: Pregnancy exposure\ndefinition : Exposure of pregnant women to toxins from any source, such as environmental toxins or chemicals, that may potentially cause problems such as miscarriage, preterm delivery, low birth weight, and, in some cases, developmental delays in infants.\nsynonyms :Exposure during pregnancy\n'}


{'id': 'HP_0031438', 'url': 'http://purl.obolibrary.org/obo/HP_0031438', 'lbl': 'Abnormal sex hormone-binding globulin level', 'desc': 'label: Abnormal sex hormone-binding globulin level\ndefinition : A deviation from the normal concentration in the circulation of sex hormone-binding globulin, a circulating glycoprotein that transports testosterone and other steroids in the blood.\nsynonyms :\n'}


{'id': 'HP_0031439', 'url': 'http://purl.obolibrary.org/obo/HP_0031439', 'lbl': 'Abnormal angiostatin level', 'desc': 'label: Abnormal angiostatin level\ndefinition : A deviation from the normal concentration in the circulation of angiostatin, an endogenous angiogenesis inhibitor, which blocks the growth of new blood vessels.\nsynonyms :\n'}


{'id': 'HP_0031440', 'url': 'http://purl.obolibrary.org/obo/HP_0031440', 'lbl': 'obsolete Abnormal tricuspid valve morphology', 'desc': 'label: obsolete Abnormal tricuspid valve morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031441', 'url': 'http://purl.obolibrary.org/obo/HP_0031441', 'lbl': 'Abnormal tricuspid valve annulus morphology', 'desc': 'label: Abnormal tricuspid valve annulus morphology\ndefinition : Any structural anomaly of the annulus of the tricuspid valve. The annulus is a ring composed of fibrous and myocardial tissue and is the structure onto which the cusps of the valve attach.\nsynonyms :\n'}


{'id': 'HP_0031442', 'url': 'http://purl.obolibrary.org/obo/HP_0031442', 'lbl': 'Abnormal tricuspid chordae tendinae morphology', 'desc': 'label: Abnormal tricuspid chordae tendinae morphology\ndefinition : Any structural anomaly of the chordae tendinae of the tricuspid valve. The chordae tendineae connect the papillary muscles to the tricuspid valve.\nsynonyms :\n'}


{'id': 'HP_0031443', 'url': 'http://purl.obolibrary.org/obo/HP_0031443', 'lbl': 'Abnormal tricuspid valve leaflet morphology', 'desc': 'label: Abnormal tricuspid valve leaflet morphology\ndefinition : Any structural anomaly of the leaflets (also known as cusps) of the tricuspid valve.\nsynonyms :\n'}


{'id': 'HP_0031444', 'url': 'http://purl.obolibrary.org/obo/HP_0031444', 'lbl': 'Dilatation of the tricuspid annulus', 'desc': 'label: Dilatation of the tricuspid annulus\ndefinition : An increase in the diameter of the ring (annulus) of the tricuspid valve.\nsynonyms :\n'}


{'id': 'HP_0031445', 'url': 'http://purl.obolibrary.org/obo/HP_0031445', 'lbl': 'Oral mucosa nodule', 'desc': 'label: Oral mucosa nodule\ndefinition : A palpable, solid lesion greater than 5mm in diameter. that is located in the mucosa of the mouth.\nsynonyms :\n'}


{'id': 'HP_0031446', 'url': 'http://purl.obolibrary.org/obo/HP_0031446', 'lbl': 'Erosion of oral mucosa', 'desc': 'label: Erosion of oral mucosa\ndefinition : Loss of the superficial layer of the oral mucosa usually resulting in a shallow or crusted lesion.\nsynonyms :\n'}


{'id': 'HP_0031447', 'url': 'http://purl.obolibrary.org/obo/HP_0031447', 'lbl': 'Penile freckling', 'desc': 'label: Penile freckling\ndefinition : Multiple pigmented macules located on the skin of the penis.\nsynonyms :\n'}


{'id': 'HP_0031448', 'url': 'http://purl.obolibrary.org/obo/HP_0031448', 'lbl': 'Herpetiform vesicles', 'desc': 'label: Herpetiform vesicles\ndefinition : Multiple vesicles distributed in multiple distinct groups consisting of multiple adjacent vesicles.\nsynonyms :\n'}


{'id': 'HP_0031449', 'url': 'http://purl.obolibrary.org/obo/HP_0031449', 'lbl': 'Perineal hemangioma', 'desc': 'label: Perineal hemangioma\ndefinition : Hemangioma, a benign tumor of the vascular endothelial cells, located in the perineal region, i.e., the region between the anus and the genitals.\nsynonyms :\n'}


{'id': 'HP_0031450', 'url': 'http://purl.obolibrary.org/obo/HP_0031450', 'lbl': 'Polycyclic', 'desc': 'label: Polycyclic\ndefinition : A distribution of skin lesions resembling multiple merged circles. For instance, this can be seen with multiple urticarial wheals as the individual, circular wheals resolve and merge.\nsynonyms :\n'}


{'id': 'HP_0031451', 'url': 'http://purl.obolibrary.org/obo/HP_0031451', 'lbl': 'Lower extremity subcutanous fat hypertrophy', 'desc': 'label: Lower extremity subcutanous fat hypertrophy\ndefinition : An abnormal increase in the amount of subcutaneous fat in the legs.\nsynonyms :\n'}


{'id': 'HP_0031452', 'url': 'http://purl.obolibrary.org/obo/HP_0031452', 'lbl': 'Lichenoid skin lesion', 'desc': 'label: Lichenoid skin lesion\ndefinition : Mutliple skin lesions resembling those characteristic of the disease lichen planus. These lesions are violaceous (reddish-purple), shiny, isolated, flat-topped papules and plaques.\nsynonyms :\n'}


{'id': 'HP_0031453', 'url': 'http://purl.obolibrary.org/obo/HP_0031453', 'lbl': 'Oral lichenoid lesion', 'desc': 'label: Oral lichenoid lesion\ndefinition : Mutliple lesions of the oral mucosa resembling those characteristic of the disease lichen planus. These are symmetric reticular lesions that resemble a white, lacelike network, as well as by papules, plaques, erythematous lesions, and erosions.\nsynonyms :\n'}


{'id': 'HP_0031454', 'url': 'http://purl.obolibrary.org/obo/HP_0031454', 'lbl': 'Apocrine hidrocystoma', 'desc': 'label: Apocrine hidrocystoma\ndefinition : A cystic lesions that forms a benign tumor of an apocrine sweat gland.\nsynonyms :\n'}


{'id': 'HP_0031455', 'url': 'http://purl.obolibrary.org/obo/HP_0031455', 'lbl': 'Presacral ganglioneuroma', 'desc': 'label: Presacral ganglioneuroma\ndefinition : A gangioleneuroma originating from sympathetic ganglion cells in the abdomen.\nsynonyms :\n'}


{'id': 'HP_0031456', 'url': 'http://purl.obolibrary.org/obo/HP_0031456', 'lbl': 'Ectopic pregnancy', 'desc': 'label: Ectopic pregnancy\ndefinition : A pregnancy in which the fertilized egg inserts in a location outside of the main cavity of the uterus (usually in the Fallopian tube).\nsynonyms :\n'}


{'id': 'HP_0031457', 'url': 'http://purl.obolibrary.org/obo/HP_0031457', 'lbl': 'Pulmonary opacity', 'desc': 'label: Pulmonary opacity\ndefinition : Opacity refers to any area that preferentially attenuates the x-ray beam and therefore appears more opaque than the surrounding area. It is a nonspecific term that does not indicate the size or pathologic nature of the abnormality.\nsynonyms :\n'}


{'id': 'HP_0031458', 'url': 'http://purl.obolibrary.org/obo/HP_0031458', 'lbl': 'Adenoiditis', 'desc': 'label: Adenoiditis\ndefinition : An inflammation of the adenoid tissue.\nsynonyms :\n'}


{'id': 'HP_0031459', 'url': 'http://purl.obolibrary.org/obo/HP_0031459', 'lbl': 'Soft tissue neoplasm', 'desc': 'label: Soft tissue neoplasm\ndefinition : A tumor (abnormal growth of tissue) that arises from the soft tissue. The most common types are lipomatous (fatty), vascular, smooth muscle, fibrous, and fibrohistiocytic neoplasms.\nsynonyms :\n'}


{'id': 'HP_0031460', 'url': 'http://purl.obolibrary.org/obo/HP_0031460', 'lbl': 'Benign muscle neoplasm', 'desc': 'label: Benign muscle neoplasm\ndefinition : A benign mesenchymal neoplasm arising from smooth, skeletal, or cardiac muscle tissue [NCIT:C4882].\nsynonyms :\n'}


{'id': 'HP_0031461', 'url': 'http://purl.obolibrary.org/obo/HP_0031461', 'lbl': 'Intramuscular Myxoma', 'desc': 'label: Intramuscular Myxoma\ndefinition : A benign tumor that is usually solitary, painless, palpable mass that is firm in consistency and slightly movable and often fluctuant. It can occur in any location, but tends to involve the muscles of the thighs, buttocks, and shoulders. On microscopic examination, there is abundant mucoid material and relative hypo cellularity and loose reticulin fibers. Vascular structures are sparse. The cells have a stellate shape with small hyper chromatic pyknotic nuclei and scanty cytoplasm. Some myxomas may show focal areas of hyper cellularity. However absence of nuclear atypia, mitotic figures or necrosis helps to rule out malignancy.\nsynonyms :IM Myxoma\n'}


{'id': 'HP_0031462', 'url': 'http://purl.obolibrary.org/obo/HP_0031462', 'lbl': 'Musculotendinous retraction', 'desc': 'label: Musculotendinous retraction\ndefinition : Abnormal reduction in length of a tendon which tends to pull (retract) the attached muscle tissue with shortening of the muscle fibers often accompanied by atrophy and fatty degeneration of the affected muscle tissue.\nsynonyms :\n'}


{'id': 'HP_0031463', 'url': 'http://purl.obolibrary.org/obo/HP_0031463', 'lbl': 'Esophageal squamous papilloma', 'desc': 'label: Esophageal squamous papilloma\ndefinition : A rare benign epithelial tumor that is usually asymptomatic but can present with pyrosis and epigastric discomfort with or without dysphagia. Histopathologically, esophageal squamous papilloma has fingerlike projections lined with acanthotic stratified squamous epithelium with conservation of normal cellular with or without cellular atypia.\nsynonyms :\n'}


{'id': 'HP_0031464', 'url': 'http://purl.obolibrary.org/obo/HP_0031464', 'lbl': 'Genital blistering', 'desc': 'label: Genital blistering\ndefinition : The presence of one or more bullae on the skin of the genital region, defined as fluid-filled blisters more than 5 mm in diameter with thin walls.\nsynonyms :\n'}


{'id': 'HP_0031465', 'url': 'http://purl.obolibrary.org/obo/HP_0031465', 'lbl': 'Abnormal vasa vasorum morphology', 'desc': 'label: Abnormal vasa vasorum morphology\ndefinition : A structural anomaly of vasa vasorum, which are defined as small blood vessels that supply or drain the walls of larger arteries and veins, delivering nutrients and oxygen as well as removing systemic waste products.\nsynonyms :\n'}


{'id': 'HP_0031466', 'url': 'http://purl.obolibrary.org/obo/HP_0031466', 'lbl': 'Impairment in personality functioning', 'desc': 'label: Impairment in personality functioning\ndefinition : A maladaptive personality trait characterized by moderate or greater impairment in personality (self /interpersonal) functioning.\nsynonyms :\n'}


{'id': 'HP_0031467', 'url': 'http://purl.obolibrary.org/obo/HP_0031467', 'lbl': 'Negative affectivity', 'desc': 'label: Negative affectivity\ndefinition : A stable tendency to experience negative emotions, i.e., a disposition to experience aversive emotional states.\nsynonyms :\n'}


{'id': 'HP_0031468', 'url': 'http://purl.obolibrary.org/obo/HP_0031468', 'lbl': 'Separation insecurity', 'desc': 'label: Separation insecurity\ndefinition : Fears of rejection by and/or separation from significant others, associated with fears of excessive dependency and complete loss of autonomy.\nsynonyms :\n'}


{'id': 'HP_0031469', 'url': 'http://purl.obolibrary.org/obo/HP_0031469', 'lbl': 'Low self esteem', 'desc': 'label: Low self esteem\ndefinition : Negative opinion about oneself characterized by low self-confidence and exaggeratedly critical feelings about oneself.\nsynonyms :\n'}


{'id': 'HP_0031472', 'url': 'http://purl.obolibrary.org/obo/HP_0031472', 'lbl': 'Risk taking', 'desc': "label: Risk taking\ndefinition : Engagement in dangerous, risky, and potentially self-damaging activities, unnecessarily and without regard to consequences; lack of concern for one's limitations and denial of the reality or personal danger.\nsynonyms :\n"}


{'id': 'HP_0031473', 'url': 'http://purl.obolibrary.org/obo/HP_0031473', 'lbl': 'Hostility', 'desc': 'label: Hostility\ndefinition : Persistent or frequent angry feelings; anger or irritability in response to minor slights and insults.\nsynonyms :\n'}


{'id': 'HP_0031474', 'url': 'http://purl.obolibrary.org/obo/HP_0031474', 'lbl': 'Pulmonary chondroma', 'desc': 'label: Pulmonary chondroma\ndefinition : A benign cartilaginous tumors of the lung.\nsynonyms :\n'}


{'id': 'HP_0031475', 'url': 'http://purl.obolibrary.org/obo/HP_0031475', 'lbl': 'Status epilepticus without prominent motor symptoms', 'desc': 'label: Status epilepticus without prominent motor symptoms\ndefinition : There is inconclusive evidence to precisely define the duration of the seizure; however, based on current evidence an operational threshold of 10 minutes is appropriate as beyond this a seizure is likely to be more prolonged. The individual may or may not be aware or in coma.\nsynonyms :Nonconvulsive status epilepticus\n'}


{'id': 'HP_0031476', 'url': 'http://purl.obolibrary.org/obo/HP_0031476', 'lbl': 'Abnormal buccal mucosa cell morphology', 'desc': 'label: Abnormal buccal mucosa cell morphology\ndefinition : Any structural anomaly of the cells of the mucosa of the oral cavity in the region of the cheek (buccal mucosa cells).\nsynonyms :\n'}


{'id': 'HP_0031477', 'url': 'http://purl.obolibrary.org/obo/HP_0031477', 'lbl': 'obsolete Abnormal mitral valve morphology', 'desc': 'label: obsolete Abnormal mitral valve morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031478', 'url': 'http://purl.obolibrary.org/obo/HP_0031478', 'lbl': 'Abnormal mitral valve annulus morphology', 'desc': 'label: Abnormal mitral valve annulus morphology\ndefinition : Any structural anomaly of the annulus of the mitral valve. The annulus is a ring composed of fibrous and myocardial tissue and is the structure onto which the cusps of the valve attach.\nsynonyms :\n'}


{'id': 'HP_0031479', 'url': 'http://purl.obolibrary.org/obo/HP_0031479', 'lbl': 'Dilatation of the mitral annulus', 'desc': 'label: Dilatation of the mitral annulus\ndefinition : An increase in the diameter of the ring (annulus) of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0031480', 'url': 'http://purl.obolibrary.org/obo/HP_0031480', 'lbl': 'Abnormal mitral valve leaflet morphology', 'desc': 'label: Abnormal mitral valve leaflet morphology\ndefinition : Any structural anomaly of the leaflets (also known as cusps) of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0031481', 'url': 'http://purl.obolibrary.org/obo/HP_0031481', 'lbl': 'Abnormal mitral valve physiology', 'desc': 'label: Abnormal mitral valve physiology\ndefinition : Any functional anomaly of the mitral valve.\nsynonyms :\n'}


{'id': 'HP_0031482', 'url': 'http://purl.obolibrary.org/obo/HP_0031482', 'lbl': 'Abnormal regional left ventricular contraction', 'desc': 'label: Abnormal regional left ventricular contraction\ndefinition : A wall motion abnormality observed upon left ventricular contraction that affects a specific region of the left ventricle.\nsynonyms :\n'}


{'id': 'HP_0031483', 'url': 'http://purl.obolibrary.org/obo/HP_0031483', 'lbl': 'Reduced contraction of the left ventricular apex', 'desc': 'label: Reduced contraction of the left ventricular apex\ndefinition : Reduced wall motion (contraction) of the apex of the left ventricle. This manifestation can be observed on echocardiography.\nsynonyms :\n'}


{'id': 'HP_0031484', 'url': 'http://purl.obolibrary.org/obo/HP_0031484', 'lbl': 'Cold-induced hemolysis', 'desc': 'label: Cold-induced hemolysis\ndefinition : A form of hemolytic anemia that can be triggered by cold temperatures.\nsynonyms :\n'}


{'id': 'HP_0031485', 'url': 'http://purl.obolibrary.org/obo/HP_0031485', 'lbl': 'Subperiosteal bone formation', 'desc': 'label: Subperiosteal bone formation\ndefinition : The formation of new bone along the cortex and underneath the periosteum of a bone.\nsynonyms :Periosteal reaction\n'}


{'id': 'HP_0031486', 'url': 'http://purl.obolibrary.org/obo/HP_0031486', 'lbl': 'Vascular malformation of the lip', 'desc': 'label: Vascular malformation of the lip\ndefinition : An anomaly of blood vessels located in the lip.\nsynonyms :\n'}


{'id': 'HP_0031487', 'url': 'http://purl.obolibrary.org/obo/HP_0031487', 'lbl': 'Capillary malformation of the lip', 'desc': 'label: Capillary malformation of the lip\ndefinition : A vascular malformation located in the lip that is characterized by\nectatic papillary dermal capillaries and postcapillary venules in the upper reticular dermis.\nsynonyms :\n'}


{'id': 'HP_0031488', 'url': 'http://purl.obolibrary.org/obo/HP_0031488', 'lbl': 'Arteriovenous malformation of the lip', 'desc': 'label: Arteriovenous malformation of the lip\ndefinition : A vascular malformation located in the lip that is characterized by direct blood shunting from an artery to a vein due to the absence of a capillary bed. The artery and vein can be directly connected by a fistula or indirectly connected by an abnormal vessel channel termed a nidus.\nsynonyms :Atypical connection between arteries and veins\n'}


{'id': 'HP_0031489', 'url': 'http://purl.obolibrary.org/obo/HP_0031489', 'lbl': 'Venous malformation of the lip', 'desc': 'label: Venous malformation of the lip\ndefinition : A vascular malformation located in the lip that is related to abnormal vascular morphogenesis.\nsynonyms :\n'}


{'id': 'HP_0031490', 'url': 'http://purl.obolibrary.org/obo/HP_0031490', 'lbl': 'Hemangioma of the lip', 'desc': 'label: Hemangioma of the lip\ndefinition : A vascular malformation located in the lip that is related to vascular endothelial cell hyperplasia.\nsynonyms :\n'}


{'id': 'HP_0031491', 'url': 'http://purl.obolibrary.org/obo/HP_0031491', 'lbl': 'Continuous spike and waves during slow sleep', 'desc': 'label: Continuous spike and waves during slow sleep\ndefinition : Diffuse, bilateral and recently also unilateral or focal localization spike-wave occurring in slow sleep or non-rapid eye movement sleep.\nsynonyms :CSWS; Electrical status epilepticus during slow-wave sleep\n'}


{'id': 'HP_0031492', 'url': 'http://purl.obolibrary.org/obo/HP_0031492', 'lbl': 'Epithelial neoplasm', 'desc': 'label: Epithelial neoplasm\ndefinition : A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas [NCIT:C3709].\nsynonyms :\n'}


{'id': 'HP_0031493', 'url': 'http://purl.obolibrary.org/obo/HP_0031493', 'lbl': 'Glandular cell neoplasm', 'desc': 'label: Glandular cell neoplasm\ndefinition : A tumor that arises from a gland cell.\nsynonyms :\n'}


{'id': 'HP_0031494', 'url': 'http://purl.obolibrary.org/obo/HP_0031494', 'lbl': 'Ovarian mucinous tumor', 'desc': 'label: Ovarian mucinous tumor\ndefinition : Ovarian mucinous neoplasms consist of borderline tumors (tumors of low malignant potential, or LMP tumors), intraepithelial (non-invasive) carcinoma, and invasive carcinoma.\nsynonyms :Mucinous neoplasm of the ovary; Ovarian mucinous tumour\n'}


{'id': 'HP_0031495', 'url': 'http://purl.obolibrary.org/obo/HP_0031495', 'lbl': 'Mucinous neoplasm', 'desc': 'label: Mucinous neoplasm\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031496', 'url': 'http://purl.obolibrary.org/obo/HP_0031496', 'lbl': 'Mucinous cystic neoplasm of the pancreas', 'desc': 'label: Mucinous cystic neoplasm of the pancreas\ndefinition : Mucin-producing and septated cyst-forming epithelial neoplasia of the pancreas with a distinctive ovarian-type stroma.\nsynonyms :\n'}


{'id': 'HP_0031497', 'url': 'http://purl.obolibrary.org/obo/HP_0031497', 'lbl': 'Mucinous colorectal carcinoma', 'desc': 'label: Mucinous colorectal carcinoma\ndefinition : A subtype of colorectal carcinoma with mucin lakes.\nsynonyms :\n'}


{'id': 'HP_0031498', 'url': 'http://purl.obolibrary.org/obo/HP_0031498', 'lbl': 'Mucinous gastric carcinoma', 'desc': 'label: Mucinous gastric carcinoma\ndefinition : A poorly differentiated type of gastric carcinoma with a substantial amount of extracellular mucus (over 50% of tumor volume) within the tumor.\nsynonyms :\n'}


{'id': 'HP_0031499', 'url': 'http://purl.obolibrary.org/obo/HP_0031499', 'lbl': 'Appendiceal mucinous neoplasm', 'desc': 'label: Appendiceal mucinous neoplasm\ndefinition : An epithelial neoplasm originating in the appendix and often associated with cystic dilation of the appendix due to accumulation of gelatinous material, morphologically referred to as mucoceles.\nsynonyms :\n'}


{'id': 'HP_0031500', 'url': 'http://purl.obolibrary.org/obo/HP_0031500', 'lbl': 'Abdominal mass', 'desc': 'label: Abdominal mass\ndefinition : An abnormal enlargement or swelling in the abdomen.\nsynonyms :\n'}


{'id': 'HP_0031501', 'url': 'http://purl.obolibrary.org/obo/HP_0031501', 'lbl': 'Pelvic mass', 'desc': 'label: Pelvic mass\ndefinition : An abnormal enlargement or swelling in the pelvic region.\nsynonyms :\n'}


{'id': 'HP_0031502', 'url': 'http://purl.obolibrary.org/obo/HP_0031502', 'lbl': 'Trophoblastic tumor', 'desc': 'label: Trophoblastic tumor\ndefinition : A gestational or non-gestational neoplasm composed of neoplastic trophoblastic cells [NCIT:C3422].\nsynonyms :Trophoblastic tumour\n'}


{'id': 'HP_0031503', 'url': 'http://purl.obolibrary.org/obo/HP_0031503', 'lbl': 'Night gasping', 'desc': 'label: Night gasping\ndefinition : Waking up at night gasping for breath.\nsynonyms :\n'}


{'id': 'HP_0031504', 'url': 'http://purl.obolibrary.org/obo/HP_0031504', 'lbl': 'Foamy urine', 'desc': 'label: Foamy urine\ndefinition : Urine has an increased amount of frothy fine bubbles.\nsynonyms :Frothy urine\n'}


{'id': 'HP_0031505', 'url': 'http://purl.obolibrary.org/obo/HP_0031505', 'lbl': 'Abnormal circulating T4 concentration', 'desc': 'label: Abnormal circulating T4 concentration\ndefinition : A deviation from the normal concentration of thyroxine in the blood. Thyroxine (also known as T4) is the main hormone secreted by the thyroid gland into the blood. It can be converted into the active form triiodothyronine (also known as T3).\nsynonyms :Abnormal circulating T4 level; Abnormal circulating thyroxine level\n'}


{'id': 'HP_0031506', 'url': 'http://purl.obolibrary.org/obo/HP_0031506', 'lbl': 'Increased circulating T4 concentration', 'desc': 'label: Increased circulating T4 concentration\ndefinition : An elevation above the normal concentration of thyroxine in the blood. Thyroxine (also known as T4) is the main hormone secreted by the thyroid gland into the blood. It can be converted into the active form triiodothyronine (also known as T3).\nsynonyms :Increased circulating T4 level; Increased circulating thyroxine level\n'}


{'id': 'HP_0031507', 'url': 'http://purl.obolibrary.org/obo/HP_0031507', 'lbl': 'Decreased circulating T4 concentration', 'desc': 'label: Decreased circulating T4 concentration\ndefinition : A reduction below the normal concentration of thyroxine in the blood. Thyroxine (also known as T4) is the main hormone secreted by the thyroid gland into the blood. It can be converted into the active form triiodothyronine (also known as T3).\nsynonyms :Decreased circulating T4 level; Decreased circulating thyroxine level; Reduced T4 plasma level\n'}


{'id': 'HP_0031508', 'url': 'http://purl.obolibrary.org/obo/HP_0031508', 'lbl': 'Abnormal circulating thyroid hormone concentration', 'desc': 'label: Abnormal circulating thyroid hormone concentration\ndefinition : Any deviation from the normal range of the hormones produced by the thyroid gland.\nsynonyms :Abnormal thyroid hormone level\n'}


{'id': 'HP_0031509', 'url': 'http://purl.obolibrary.org/obo/HP_0031509', 'lbl': 'Dry nipple', 'desc': 'label: Dry nipple\ndefinition : Abnormally dry skin in the area of the nipple of the breast.\nsynonyms :\n'}


{'id': 'HP_0031510', 'url': 'http://purl.obolibrary.org/obo/HP_0031510', 'lbl': 'Linear earlobe crease', 'desc': 'label: Linear earlobe crease\ndefinition : A transverse linear fissure (crease) in the lobule of the ear.\nsynonyms :\n'}


{'id': 'HP_0031511', 'url': 'http://purl.obolibrary.org/obo/HP_0031511', 'lbl': 'Diagonal earlobe crease', 'desc': 'label: Diagonal earlobe crease\ndefinition : Diagonal earlobe creases run from the lower pole of the external meatus, diagonally backwards to the edge of the lobe at approximately 45 degrees.\nsynonyms :\n'}


{'id': 'HP_0031512', 'url': 'http://purl.obolibrary.org/obo/HP_0031512', 'lbl': 'Abnormal cutaneous collagen fibril morphology', 'desc': 'label: Abnormal cutaneous collagen fibril morphology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0031513', 'url': 'http://purl.obolibrary.org/obo/HP_0031513', 'lbl': 'Luse bodies', 'desc': 'label: Luse bodies\ndefinition : Fusiform collagen fibers with abnormally long spacing (exceeding 100 nm) between electron-dense bands.\nsynonyms :\n'}


{'id': 'HP_0031514', 'url': 'http://purl.obolibrary.org/obo/HP_0031514', 'lbl': 'Increased proportion of exhausted T cells', 'desc': 'label: Increased proportion of exhausted T cells\ndefinition : An abnormally elevated proportion of exhausted T cells (Tex) among circulating T cells. T cell exhaustion is a distinct differentiation state that can be distinguished from naive, effector, and memory T cells. Compared to effector (TE) and memory (TMEM) T cells, exhausted T cells (TEX) display impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity). TEX have limited proliferative potential, especially compared to some subsets of TMEM and naive T cells.\nsynonyms :\n'}


{'id': 'HP_0031515', 'url': 'http://purl.obolibrary.org/obo/HP_0031515', 'lbl': 'Abnormal meiosis', 'desc': 'label: Abnormal meiosis\ndefinition : Any anomaly of meiosis, a type of cell division that reduces the number of chromosomes in the parent cell by half and produces four gamete cells.\nsynonyms :\n'}


{'id': 'HP_0031516', 'url': 'http://purl.obolibrary.org/obo/HP_0031516', 'lbl': 'Oocyte arrest at metaphase I', 'desc': 'label: Oocyte arrest at metaphase I\ndefinition : Failure of oocytes to proceed through the stages of meiosis with stoppage at the first metaphase stage.\nsynonyms :Metaphase I oocyte meiotic arrest; Oocyte meiotic arrest at metaphase I\n'}


{'id': 'HP_0031517', 'url': 'http://purl.obolibrary.org/obo/HP_0031517', 'lbl': 'Verruciform xanthoma', 'desc': 'label: Verruciform xanthoma\ndefinition : A papillary or cauliflower-like growth characterized by the presence of foamy histiocytes within the elongated dermal papillae forms.\nsynonyms :\n'}


{'id': 'HP_0031518', 'url': 'http://purl.obolibrary.org/obo/HP_0031518', 'lbl': 'Absent posterior alpha rhythm', 'desc': 'label: Absent posterior alpha rhythm\ndefinition : Lack of normal alpha rhythm in the EEG. Alpha rhythm has been defined as a rhythm at 8-13 Hz occurring during wakefulness over the posterior regions of the head, generally with higher voltage over the occipital areas. Amplitude is variable but is mostly below 50 microvolt in adults. It is best seen with eyes closed and under conditions of physical relaxation and relative mental inactivity. It is blocked or attenuated by attention, especially visual and mental effort. One should here note the difference between the terms alpha rhythm and alpha activity: Alpha activity refers to activity in the range of 8-13 Hz and alpha rhythm is the activity of 8-13 Hz with specific characteristics as defined above.\nsynonyms :\n'}


{'id': 'HP_0031519', 'url': 'http://purl.obolibrary.org/obo/HP_0031519', 'lbl': 'Cauliflower deformity of dermal collagen fibrils', 'desc': 'label: Cauliflower deformity of dermal collagen fibrils\ndefinition : An anomaly of collagen fibers of the skin that is said to resemble a cauliflower and can be appreciated by electron microscopy.\nsynonyms :\n'}


{'id': 'HP_0031520', 'url': 'http://purl.obolibrary.org/obo/HP_0031520', 'lbl': 'Groin pain', 'desc': 'label: Groin pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the groin region.\nsynonyms :\n'}


{'id': 'HP_0031521', 'url': 'http://purl.obolibrary.org/obo/HP_0031521', 'lbl': 'Vaginal clear cell adenocarcinoma', 'desc': 'label: Vaginal clear cell adenocarcinoma\ndefinition : A type of adenocarcinoma originating in the vagina and characterized by large cells with moderate to abundant clear cytoplasm.\nsynonyms :Clear cell adenocarcinoma of the vagina\n'}


{'id': 'HP_0031522', 'url': 'http://purl.obolibrary.org/obo/HP_0031522', 'lbl': 'Cervical clear cell adenocarcinoma', 'desc': 'label: Cervical clear cell adenocarcinoma\ndefinition : A type of adenocarcinoma originating in the cervix and characterized by large cells with moderate to abundant clear cytoplasm.\nsynonyms :Clear cell carcinoma of cervix\n'}


{'id': 'HP_0031523', 'url': 'http://purl.obolibrary.org/obo/HP_0031523', 'lbl': 'Salivary gland oncocytoma', 'desc': 'label: Salivary gland oncocytoma\ndefinition : A benign epithelial neoplasm composed of layers of oncocytes (small round nucleus, micro-granular, eosinophilic cytoplasm with numerous tightly-packed mitochondria)\nsynonyms :Parotid oncocytoma\n'}


{'id': 'HP_0031524', 'url': 'http://purl.obolibrary.org/obo/HP_0031524', 'lbl': 'Ampulla of Vater carcinoma', 'desc': 'label: Ampulla of Vater carcinoma\ndefinition : A carcinoma originating in the ampulla of Vater (also known as the hepatopancreatic duct), which is formed by the union of the pancreatic duct and the common bile duct.\nsynonyms :\n'}


{'id': 'HP_0031525', 'url': 'http://purl.obolibrary.org/obo/HP_0031525', 'lbl': 'Keratoacanthoma', 'desc': 'label: Keratoacanthoma\ndefinition : Keratoacanthoma (KA) is a common benign epithelial tumor that originates from the pilosebaceous glands. In most cases, it is characterized by rapid evolution, followed by spontaneous resolution over 4 to 6 months. KA usually presents as a solitary flesh-coloured nodule with a central keratin plug on the sun-exposed skin of elderly individuals.\nsynonyms :\n'}


{'id': 'HP_0031526', 'url': 'http://purl.obolibrary.org/obo/HP_0031526', 'lbl': 'Subretinal fluid', 'desc': "label: Subretinal fluid\ndefinition : Edema/fluid accumulating between the retinal pigment epithelium and Bruch's membrane.\nsynonyms :Sub-retinal fluid\n"}


{'id': 'HP_0031527', 'url': 'http://purl.obolibrary.org/obo/HP_0031527', 'lbl': 'Intraretinal fluid', 'desc': 'label: Intraretinal fluid\ndefinition : Edema/fluid accumulating within the retinal layers.\nsynonyms :Intra-retinal fluid\n'}


{'id': 'HP_0031528', 'url': 'http://purl.obolibrary.org/obo/HP_0031528', 'lbl': 'Subretinal deposits', 'desc': 'label: Subretinal deposits\ndefinition : Deposits accumulating between the outer retina and the retinal pigment epithelium.\nsynonyms :\n'}


{'id': 'HP_0031529', 'url': 'http://purl.obolibrary.org/obo/HP_0031529', 'lbl': 'Focal subretinal deposits', 'desc': 'label: Focal subretinal deposits\ndefinition : Deposits accumulating between the outer retina and the retinal pigment epithelium and that have a focal distribution.\nsynonyms :\n'}


{'id': 'HP_0031530', 'url': 'http://purl.obolibrary.org/obo/HP_0031530', 'lbl': 'Multifocal subretinal deposits', 'desc': 'label: Multifocal subretinal deposits\ndefinition : Deposits accumulating between the outer retina and the retinal pigment epithelium and that are distributed with multiple foci.\nsynonyms :\n'}


{'id': 'HP_0031531', 'url': 'http://purl.obolibrary.org/obo/HP_0031531', 'lbl': 'Sub-RPE deposits', 'desc': "label: Sub-RPE deposits\ndefinition : Deposits accumulating between the retinal pigment epithelium and Bruch's membrane.\nsynonyms :\n"}


{'id': 'HP_0031532', 'url': 'http://purl.obolibrary.org/obo/HP_0031532', 'lbl': 'Focal sub-RPE deposits', 'desc': "label: Focal sub-RPE deposits\ndefinition : Deposits accumulating between the retinal pigment epithelium and Bruch's membrane and that are distributed in a single focus.\nsynonyms :\n"}


{'id': 'HP_0031533', 'url': 'http://purl.obolibrary.org/obo/HP_0031533', 'lbl': 'Multifocal sub-RPE deposits', 'desc': "label: Multifocal sub-RPE deposits\ndefinition : Deposits accumulating between the retinal pigment epithelium and Bruch's membrane and that are distributed in multiple foci.\nsynonyms :\n"}


{'id': 'HP_0031534', 'url': 'http://purl.obolibrary.org/obo/HP_0031534', 'lbl': 'Passive dorsiflexion of the 5th finger more than 90 degrees', 'desc': "label: Passive dorsiflexion of the 5th finger more than 90 degrees\ndefinition : An abnormally increased ability to bend (dorsiflex) one's fifth finger. To assess this feature, the examiner requests to proband to extend the elbows,to bend the wrist back so that it forms a ninety degree angle to the forearm, and to extend the fingers. Then, the proband is requested to bend the fifth finger back as far as is possible without discomfort. If the angle of the fifth finger exceeds 90 degrees, this is considered to be abnormal.\nsynonyms :\n"}


{'id': 'HP_0031535', 'url': 'http://purl.obolibrary.org/obo/HP_0031535', 'lbl': 'Increased theta frequency activity in EEG', 'desc': 'label: Increased theta frequency activity in EEG\ndefinition : Increased frequency of theta wave activity in the electroencephalogram. Theta waves have a frequency of 3.5-7.5 Hertz, and are present in very small amounts in healthy waking adult EEGs. Theta activity is normal in small very amounts in the healthy waking adult EEG in a symmetrical distribution.\nsynonyms :\n'}


{'id': 'HP_0031536', 'url': 'http://purl.obolibrary.org/obo/HP_0031536', 'lbl': 'Separate origin of the left anterior descending and left circumflex artery', 'desc': 'label: Separate origin of the left anterior descending and left circumflex artery\ndefinition : Anomalous coronary origin whereby the left anterior descending (LAD) and the left circumflex artery (LCX) arise separately. Normally, these arteries arise from a common stem, the left main coronary artery (LMCA).\nsynonyms :\n'}


{'id': 'HP_0031537', 'url': 'http://purl.obolibrary.org/obo/HP_0031537', 'lbl': 'Anomalous origin of the left circumflex artery from the right coronary artery', 'desc': 'label: Anomalous origin of the left circumflex artery from the right coronary artery\ndefinition : An abnormal origin of the left circumflex artery (LCX) from the right coronary artery. Normally, the left anterior descending (LAD) and the LCX arise from a common stem, the left main coronary artery (LMCA).\nsynonyms :\n'}


{'id': 'HP_0031538', 'url': 'http://purl.obolibrary.org/obo/HP_0031538', 'lbl': 'Abnormal dermoepidermal junction morphology', 'desc': 'label: Abnormal dermoepidermal junction morphology\ndefinition : Any anomaly of the structure of the acellular zone that is between the dermis and the epidermis and which functions to bind the epidermis to the dermis and to serve as a selective barrier allowing the control of molecular and cellular exchanges between the two compartments.\nsynonyms :\n'}


{'id': 'HP_0031539', 'url': 'http://purl.obolibrary.org/obo/HP_0031539', 'lbl': 'Linear IgA deposits along the epidermal basement membrane zone', 'desc': 'label: Linear IgA deposits along the epidermal basement membrane zone\ndefinition : Presence of IgA antibodies in the dermoepidermal junction that are distributed in a linear pattern. This feature can be appreciated by immunofluorescence microscopy.\nsynonyms :\n'}


{'id': 'HP_0031540', 'url': 'http://purl.obolibrary.org/obo/HP_0031540', 'lbl': 'Linear IgG deposits along the epidermal basement membrane zone', 'desc': 'label: Linear IgG deposits along the epidermal basement membrane zone\ndefinition : Presence of IgG antibodies in the dermoepidermal junction that are distributed in a linear pattern. This feature can be appreciated by immunofluorescence microscopy.\nsynonyms :\n'}


{'id': 'HP_0031541', 'url': 'http://purl.obolibrary.org/obo/HP_0031541', 'lbl': 'Linear C3 deposits along the epidermal basement membrane zone', 'desc': 'label: Linear C3 deposits along the epidermal basement membrane zone\ndefinition : Presence of complement C3 in the dermoepidermal junction that are distributed in a linear pattern. This feature can be appreciated by immunofluorescence microscopy.\nsynonyms :\n'}


{'id': 'HP_0031542', 'url': 'http://purl.obolibrary.org/obo/HP_0031542', 'lbl': 'Myelin-like whorls in vacuolated fibers', 'desc': 'label: Myelin-like whorls in vacuolated fibers\ndefinition : Muscle fibers contain one or more vacuoles (membrane-bound cavity) associated with collections of membranes arranged in a whorl-like (spiral or circular) manner.\nsynonyms :Myelin-like whorls in vacuolated fibres\n'}


{'id': 'HP_0031544', 'url': 'http://purl.obolibrary.org/obo/HP_0031544', 'lbl': 'Elevated circulating palmitoleylcarnitine concentration', 'desc': 'label: Elevated circulating palmitoleylcarnitine concentration\ndefinition : An elevated level of propionylcarnitine in the circulation. Propionylcarnitine is present in high abundance in the urine of patients with Methylmalonyl-CoA mutase (MUT) deficiency.\nsynonyms :Elevated circulating O-propionylcarnitine concentration; Elevated plasma palmitoleylcarnitine, C16:1; Elevated plasma propionylcarnitine, C3:0; Elevated propionylcarnitine level\n'}


{'id': 'HP_0031545', 'url': 'http://purl.obolibrary.org/obo/HP_0031545', 'lbl': 'Abnormally low T cell receptor excision circle level', 'desc': 'label: Abnormally low T cell receptor excision circle level\ndefinition : Reduced level of T cell receptor excision circle (TRECs) as measured by the TREC assay. Late in maturation, 70% of thymocytes that will ultimately express alpha/beta-T cell receptors form a circular DNA TREC from the excised TCRdelta gene that lies within the TCRalpha genetic locus. The circles are stable but do not increase following cell division and, therefore, become diluted as T cells proliferate. A quantitative polymerase chain reaction (PCR) reaction across the joint of the circular DNA provides the TREC copy number, a marker of newly-formed, antigenically-naïve thymic emigrant T cells.\nsynonyms :\n'}


{'id': 'HP_0031546', 'url': 'http://purl.obolibrary.org/obo/HP_0031546', 'lbl': 'Cardiac conduction abnormality', 'desc': 'label: Cardiac conduction abnormality\ndefinition : Any anomaly of the progression of electrical impulses through the heart.\nsynonyms :Abnormality of cardiac conduction; Abnormality of cardiac conduction system; Cardiac conduction abnormalities; Cardiac conduction defects; Heart conduction disorder\n'}


{'id': 'HP_0031547', 'url': 'http://purl.obolibrary.org/obo/HP_0031547', 'lbl': 'Abnormal QT interval', 'desc': 'label: Abnormal QT interval\ndefinition : Any anomaly of the time interval between the start of the Q wave and the end of the T wave as measured by the electrocardiogram (EKG).\nsynonyms :\n'}


{'id': 'HP_0031548', 'url': 'http://purl.obolibrary.org/obo/HP_0031548', 'lbl': 'Follicular infundibulum tumor', 'desc': 'label: Follicular infundibulum tumor\ndefinition : A cutaneous adnexal neoplasm with variable clinical presentation. It tends to be located in the head and neck and the presentation is papulonodular, scaly, asymptomatic, measuring up to 1-2cm, simulating a basal cell carcinoma.\nsynonyms :Basal cell hamartoma with follicular differentiation; Follicular infundibulum tumour\n'}


{'id': 'HP_0031549', 'url': 'http://purl.obolibrary.org/obo/HP_0031549', 'lbl': 'Lymphocytoma cutis', 'desc': 'label: Lymphocytoma cutis\ndefinition : Lymphocytoma cutis, or Spiegler-Fendt sarcoid, is classed as one of the pseudolymphomas, referring to inflammatory disorders in which the accumulation of lymphocytes on the skin resemble, clinically and histopathologically, cutaneous lymphomas. Careful clinical evaluation, histopathological and immunohistochemical exams may be needed to make the correct diagnosis.\nsynonyms :Skin pseudolymphoma; Spiegler-Fendt sarcoid\n'}


{'id': 'HP_0031550', 'url': 'http://purl.obolibrary.org/obo/HP_0031550', 'lbl': 'Abnormal flow cytometry test result', 'desc': 'label: Abnormal flow cytometry test result\ndefinition : Any abnormal result of flow cytometry, a method that suspends cells in a stream of fluid and passes them through an electronic detection apparatus in order to assess cell count or measure biomarkers or surface molecules.\nsynonyms :\n'}


{'id': 'HP_0031551', 'url': 'http://purl.obolibrary.org/obo/HP_0031551', 'lbl': 'Reduced cell surface marker level', 'desc': 'label: Reduced cell surface marker level\ndefinition : Reduced level of a protein that is normally present on the cell surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031552', 'url': 'http://purl.obolibrary.org/obo/HP_0031552', 'lbl': 'Reduced fibroblast surface marker level', 'desc': 'label: Reduced fibroblast surface marker level\ndefinition : Reduced level of a protein that is normally present on the fibroblast surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031553', 'url': 'http://purl.obolibrary.org/obo/HP_0031553', 'lbl': 'Reduced granulocyte surface marker level', 'desc': 'label: Reduced granulocyte surface marker level\ndefinition : Reduced level of a protein that is normally present on the granulocyte surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031554', 'url': 'http://purl.obolibrary.org/obo/HP_0031554', 'lbl': 'Reduced granulocyte CD55 level', 'desc': 'label: Reduced granulocyte CD55 level\ndefinition : Reduced level of CD55 on the granulocyte surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031555', 'url': 'http://purl.obolibrary.org/obo/HP_0031555', 'lbl': 'Reduced granulocyte CD59 level', 'desc': 'label: Reduced granulocyte CD59 level\ndefinition : Reduced level of CD59 on the granulocyte surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031556', 'url': 'http://purl.obolibrary.org/obo/HP_0031556', 'lbl': 'Reduced granulocyte CD16 level', 'desc': 'label: Reduced granulocyte CD16 level\ndefinition : Reduced level of CD16 on the granulocyte surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031557', 'url': 'http://purl.obolibrary.org/obo/HP_0031557', 'lbl': 'Reduced fibroblast CD55 level', 'desc': 'label: Reduced fibroblast CD55 level\ndefinition : Reduced level of CD55 on the fibroblast surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031558', 'url': 'http://purl.obolibrary.org/obo/HP_0031558', 'lbl': 'Reduced fibroblast CD59 level', 'desc': 'label: Reduced fibroblast CD59 level\ndefinition : Reduced level of CD59 on the fibroblast surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031559', 'url': 'http://purl.obolibrary.org/obo/HP_0031559', 'lbl': 'Reduced fibroblast CD16 level', 'desc': 'label: Reduced fibroblast CD16 level\ndefinition : Reduced level of CD16 on the fibroblast surface as assessed by flow cytometry.\nsynonyms :\n'}


{'id': 'HP_0031560', 'url': 'http://purl.obolibrary.org/obo/HP_0031560', 'lbl': 'Coronary cameral fistula', 'desc': 'label: Coronary cameral fistula\ndefinition : An abnormal communication between coronary artery and a cardiac chamber.\nsynonyms :\n'}


{'id': 'HP_0031561', 'url': 'http://purl.obolibrary.org/obo/HP_0031561', 'lbl': 'Coronary cameral fistula to right ventricle', 'desc': 'label: Coronary cameral fistula to right ventricle\ndefinition : An abnormal communication between the terminus of a coronary artery, bypassing the myocardial capillary bed and entering the right ventricle.\nsynonyms :\n'}


{'id': 'HP_0031562', 'url': 'http://purl.obolibrary.org/obo/HP_0031562', 'lbl': 'Balanced double aortic arch', 'desc': 'label: Balanced double aortic arch\ndefinition : A type of double aortic arch in which the two branches are of equal size. In most cases of double aortic arch, the right aortic arch is larger and located higher than the left aortic arch.\nsynonyms :\n'}


{'id': 'HP_0031563', 'url': 'http://purl.obolibrary.org/obo/HP_0031563', 'lbl': 'Coronary arteriovenous fistula', 'desc': 'label: Coronary arteriovenous fistula\ndefinition : An abnormal communication between the terminus of a coronary artery, bypassing the myocardial capillary bed and entering any segment of the systemic or pulmonary circulation.\nsynonyms :\n'}


{'id': 'HP_0031564', 'url': 'http://purl.obolibrary.org/obo/HP_0031564', 'lbl': 'Bronchial isomerism', 'desc': 'label: Bronchial isomerism\ndefinition : An anomalous mirror-imaged arrangement of some bronchial structures. Right isomerism is defined as a subset of heterotaxy where some paired structures on opposite sides of the left-right axis of the body are symmetrical mirror images of each other, and have the morphology of the normal right-sided structures (vice versa for left isomerism).\nsynonyms :\n'}


{'id': 'HP_0031565', 'url': 'http://purl.obolibrary.org/obo/HP_0031565', 'lbl': 'Abdominal situs ambiguus', 'desc': 'label: Abdominal situs ambiguus\ndefinition : An abnormality in which the abdominal organs are positioned in such a way with respect to each other and the left-right axis as to be not clearly lateralised and thus have neither the usual, or normal (situs solitus), nor the mirror-imaged (situs inversus) arrangements.\nsynonyms :\n'}


{'id': 'HP_0031566', 'url': 'http://purl.obolibrary.org/obo/HP_0031566', 'lbl': 'Abnormal pulmonary valve cusp morphology', 'desc': 'label: Abnormal pulmonary valve cusp morphology\ndefinition : Any structural anomaly of the pulmonary valve leaflets.\nsynonyms :\n'}


{'id': 'HP_0031567', 'url': 'http://purl.obolibrary.org/obo/HP_0031567', 'lbl': 'Abnormal aortic valve cusp morphology', 'desc': 'label: Abnormal aortic valve cusp morphology\ndefinition : Any structural anomaly of the aortic valve leaflets.\nsynonyms :\n'}


{'id': 'HP_0031568', 'url': 'http://purl.obolibrary.org/obo/HP_0031568', 'lbl': 'Thickened aortic valve cusp', 'desc': 'label: Thickened aortic valve cusp\ndefinition : An abnormally increased thickness of a leaflet of the aortic valve.\nsynonyms :\n'}


{'id': 'HP_0031569', 'url': 'http://purl.obolibrary.org/obo/HP_0031569', 'lbl': 'Absent aortic valve cusps', 'desc': 'label: Absent aortic valve cusps\ndefinition : A developmental defect characterized by the lack of aortic valve cusps (leaflets). There may be remnants of the aortic valve in form of a nonobstructive fibrous ridge or rudimentary leaflets or sinuses of Valsalva.\nsynonyms :Absent aortic valve\n'}


{'id': 'HP_0031570', 'url': 'http://purl.obolibrary.org/obo/HP_0031570', 'lbl': 'Tessier number 0 facial cleft', 'desc': 'label: Tessier number 0 facial cleft\ndefinition : A Number 0 Tessier cleft is a true median cleft lip with a broad columella and bifid nasal tip. The alveolar cleft is between the central incisors. The nasal septum may be thickened, duplicated, or absent. The nasal bridge is usually broad with associated orbital hypertelorism. The midline soft tissue anomaly may range from a mild broadening of the philtrum or there may be a true median cleft lip. The columella and nasal tip are typically bifid and broadened with a midline depression. The alae nasi are intact but laterally displaced. The nose appears shortened in the vertical dimension.\nsynonyms :Tessier facial cleft number 0\n'}


{'id': 'HP_0031571', 'url': 'http://purl.obolibrary.org/obo/HP_0031571', 'lbl': 'Paramedian facial cleft', 'desc': 'label: Paramedian facial cleft\ndefinition : A type of facial cleft located near to but not directly on the midline of the face.\nsynonyms :\n'}