{'id': 'HP_0025186', 'url': 'http://purl.obolibrary.org/obo/HP_0025186', 'lbl': 'Marcus Gunn jaw winking synkinesis', 'desc': 'label: Marcus Gunn jaw winking synkinesis\ndefinition : Unilateral ptosis with associated upper eyelid contraction and contraction of either the external or the internal pterygoid muscle. It is thought to occur because of congenital miswiring of a branch of the fifth cranial nerve into the branch of the third cranial nerve supplying the levator muscle. In Marcus Gunn jaw winking synkinesis, elevation and even retraction of the affected eyelid is triggered by chewing, suction, lateral mandible movement, smiling, sternocleidomastoid contraction, protruding tongue, Valsalva manoeuvre and even by breathing.\nsynonyms :Marcus Gunn jaw-winking syndrome; Pterygoid-levator synkinesis; Trigemino-oculomotor synkinesis\n'}


{'id': 'HP_0025188', 'url': 'http://purl.obolibrary.org/obo/HP_0025188', 'lbl': 'Retinal vasculitis', 'desc': 'label: Retinal vasculitis\ndefinition : Inflammation of retinal blood vessels as manifested by perivascular sheathing or cuffing, vascular leakage and/or occlusion.\nsynonyms :\n'}


{'id': 'HP_0025190', 'url': 'http://purl.obolibrary.org/obo/HP_0025190', 'lbl': 'Bilateral tonic-clonic seizure with generalized onset', 'desc': 'label: Bilateral tonic-clonic seizure with generalized onset\ndefinition : A bilateral tonic-clonic seizure with generalized onset is a type of bilateral tonic-clonic seizure characterised by generalized onset; these seizures rapidly engage networks in both hemispheres at the start of the seizure.\nsynonyms :Bilateral tonic-clonic seizure with generalised onset; Generalised tonic-clonic seizure without focal onset; Generalised tonic-clonic seizure without partial onset; Generalised tonic-clonic seizures without focal onset; Generalised-onset tonic-clonic seizure; Generalized tonic-clonic seizure without focal onset; Generalized tonic-clonic seizure without partial onset; Generalized tonic-clonic seizures without focal onset; Generalized-onset tonic-clonic seizure; Primarily generalised tonic-clonic seizures; Primarily generalized tonic-clonic seizures; Primary generalised tonic-clonic seizure; Primary generalised tonic-clonic seizures; Primary generalized tonic-clonic seizure; Primary generalized tonic-clonic seizures\n'}


{'id': 'HP_0025191', 'url': 'http://purl.obolibrary.org/obo/HP_0025191', 'lbl': 'obsolete Segmental myoclonic seizures', 'desc': 'label: obsolete Segmental myoclonic seizures\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025192', 'url': 'http://purl.obolibrary.org/obo/HP_0025192', 'lbl': 'Subtentorial periventricular white matter hyperdensity', 'desc': 'label: Subtentorial periventricular white matter hyperdensity\ndefinition : Areas of brighter than expected signal on magnetic resonance imaging emanating from the cerebral white matter that surrounds the fourth cerebral ventricle (which is located beneath the tentorium of the cerebellum).\nsynonyms :\n'}


{'id': 'HP_0025193', 'url': 'http://purl.obolibrary.org/obo/HP_0025193', 'lbl': 'Posterolateral diaphragmatic hernia', 'desc': 'label: Posterolateral diaphragmatic hernia\ndefinition : A posterolateral defect in the diaphragm, commonly referred to as a Bochdalek hernia, which is often accompanied by herniation of the stomach, intestines, liver, and/or spleen into the chest cavity.\nsynonyms :Bochdalek hernia\n'}


{'id': 'HP_0025194', 'url': 'http://purl.obolibrary.org/obo/HP_0025194', 'lbl': 'Morgagni diaphragmatic hernia', 'desc': 'label: Morgagni diaphragmatic hernia\ndefinition : An anterior retrosternal or parasternal hernia that can result in the herniation of liver or intestines into the chest cavity.\nsynonyms :Morgagni hernia\n'}


{'id': 'HP_0025195', 'url': 'http://purl.obolibrary.org/obo/HP_0025195', 'lbl': 'Central diaphragmatic hernia', 'desc': 'label: Central diaphragmatic hernia\ndefinition : A congenital diaphragm defect involving the central tendinous (e.g., amuscular) portion of the diaphragm, whereby the entire rim of diaphragmatic musculature is present.\nsynonyms :Central hernia\n'}


{'id': 'HP_0025196', 'url': 'http://purl.obolibrary.org/obo/HP_0025196', 'lbl': 'Increased total iron binding capacity', 'desc': 'label: Increased total iron binding capacity\ndefinition : An elevation in the total-iron binding capacity, which measures how much serum iron is bound if an excess of radioactive iron is added. A high TIBC corresponds to a high transferrin concentration. The latent (or free) iron binding capacity is the difference between the TIBC and the measured serum iron, corresponding to the transferrin not bound to iron, i.e., free iron binding capacity.\nsynonyms :\n'}


{'id': 'HP_0025197', 'url': 'http://purl.obolibrary.org/obo/HP_0025197', 'lbl': 'Inclusion body fibromatosis', 'desc': 'label: Inclusion body fibromatosis\ndefinition : A benign tumor made up of mostly myofibroblasts that appears almost exclusively on the digits of the hands and feet, rarely involving the thumb or big toe. The lesion displays a proliferation of bland intradermal spindle cells arranged in whorls, fascicles, or a storiform pattern in a collagenous background of varying degrees. Also usually present are perpendicular tumor cell fascicles that extend to the epidermis. The small intracytoplasmic inclusions are said to appear similar to red blood cells. The inclusion bodies have been shown to be made up of densely packed vimentin and actin filaments. The tumor often causes a dome-shaped elevation of the overlying structures, forming a protuberant or polypoid nodule. The overlying epidermis can display a host of changes, including acanthosis, hyperkeratosis, parakeratosis, rete ridge flattening, entrapment of adnexal structures, and, rarely, ulceration.\nsynonyms :Digital fibrous tumor of Reye; Digital fibrous tumour of Reye; Infantile digital fibroma; Infantile digital fibromatosis\n'}


{'id': 'HP_0025198', 'url': 'http://purl.obolibrary.org/obo/HP_0025198', 'lbl': 'Inflammatory cap polyp', 'desc': 'label: Inflammatory cap polyp\ndefinition : A non-malignant sessile or pedunculated polyp in the colon and rectum that displays a cap of inflammatory granulation tissue with fibrinopurulent exudate that covers the polyp.\nsynonyms :\n'}


{'id': 'HP_0025200', 'url': 'http://purl.obolibrary.org/obo/HP_0025200', 'lbl': 'Muscle fiber actin filament accumulation', 'desc': 'label: Muscle fiber actin filament accumulation\ndefinition : Accumulation in muscle cells of filaments composed of actin.\nsynonyms :Muscle fibre actin filament accumulation\n'}


{'id': 'HP_0025201', 'url': 'http://purl.obolibrary.org/obo/HP_0025201', 'lbl': 'Abnormal circulating apolipoprotein concentration', 'desc': 'label: Abnormal circulating apolipoprotein concentration\ndefinition : A deviation from the normal concentration in blood of an apolipoprotein, i.e., of a protein that binds lipids to form lipoprotein and is thereby responsible for the transport of lipids in the blood and lymph circulation.\nsynonyms :Abnormal apolipoprotein level\n'}


{'id': 'HP_0025202', 'url': 'http://purl.obolibrary.org/obo/HP_0025202', 'lbl': 'Elevated circulating apolipoprotein A-IV concentration', 'desc': 'label: Elevated circulating apolipoprotein A-IV concentration\ndefinition : An increased concentration in blood of apolipoprotein A-IV, a major component of HDL and chylomicrons that has a role in VLDL secretion and catabolism and is required for efficient activation of lipoprotein lipase by ApoC-II.\nsynonyms :Elevated apolipoprotein A-IV level\n'}


{'id': 'HP_0025203', 'url': 'http://purl.obolibrary.org/obo/HP_0025203', 'lbl': 'Caput medusae', 'desc': 'label: Caput medusae\ndefinition : Distended and engorged umbilical veins which are seen radiating from the umbilicus across the abdomen to join systemic veins.\nsynonyms :Palm tree sign\n'}


{'id': 'HP_0025204', 'url': 'http://purl.obolibrary.org/obo/HP_0025204', 'lbl': 'Triggered by', 'desc': 'label: Triggered by\ndefinition : A trigger is defined as an external factor that leads to the manifestation of a sign or symptom in a person with a susceptibility to developing that manifestation.\nsynonyms :\n'}


{'id': 'HP_0025205', 'url': 'http://purl.obolibrary.org/obo/HP_0025205', 'lbl': 'Triggered by breast feeding', 'desc': 'label: Triggered by breast feeding\ndefinition : Applies to a sign or symptom that is provoked or brought about by breast feeding in an infant.\nsynonyms :Breastfeeding triggered symptoms; Triggered by breastfeeding\n'}


{'id': 'HP_0025206', 'url': 'http://purl.obolibrary.org/obo/HP_0025206', 'lbl': 'Triggered by cold', 'desc': 'label: Triggered by cold\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to cold surroundings.\nsynonyms :Cold triggered symptoms; Triggered by cold temperature\n'}


{'id': 'HP_0025207', 'url': 'http://purl.obolibrary.org/obo/HP_0025207', 'lbl': 'Triggered by dehydration', 'desc': 'label: Triggered by dehydration\ndefinition : Applies to a sign or symptom that is provoked or brought about by being dehydrated, i.e., by a deficit in total body water.\nsynonyms :Dehydration triggered symptoms; Triggered by dehydration\n'}


{'id': 'HP_0025208', 'url': 'http://purl.obolibrary.org/obo/HP_0025208', 'lbl': 'Triggered by carbohydrate ingestion', 'desc': 'label: Triggered by carbohydrate ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating or drinking carbohydrates.\nsynonyms :Carbohydrate ingestion triggered symptoms; Triggered by carbohydrate ingestion\n'}


{'id': 'HP_0025209', 'url': 'http://purl.obolibrary.org/obo/HP_0025209', 'lbl': 'Triggered by fructose ingestion', 'desc': 'label: Triggered by fructose ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating or drinking fructose.\nsynonyms :Trigged by fruit sugar\n'}


{'id': 'HP_0025210', 'url': 'http://purl.obolibrary.org/obo/HP_0025210', 'lbl': 'Triggered by glucose ingestion', 'desc': 'label: Triggered by glucose ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating or drinking glucose.\nsynonyms :\n'}


{'id': 'HP_0025211', 'url': 'http://purl.obolibrary.org/obo/HP_0025211', 'lbl': 'Triggered by ethanol ingestion', 'desc': 'label: Triggered by ethanol ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by drinking or otherwise ingesting ethanol.\nsynonyms :Triggered by alcohol ingestion; Ethanol ingestion triggered symptoms\n'}


{'id': 'HP_0025212', 'url': 'http://purl.obolibrary.org/obo/HP_0025212', 'lbl': 'Triggered by fasting', 'desc': 'label: Triggered by fasting\ndefinition : Applies to a sign or symptom that is provoked or brought about by abstaining from eating food (fasting).\nsynonyms :Fasting triggered attacks; Fasting triggered symptoms; Triggered by fasting\n'}


{'id': 'HP_0025213', 'url': 'http://purl.obolibrary.org/obo/HP_0025213', 'lbl': 'Triggered by galactose ingestion', 'desc': 'label: Triggered by galactose ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating or drinking galactose. Galactose usually is ingested as lactose, which is composed of equimolar amounts of glucose and galactose.\nsynonyms :Triggered by ingestion of lactose-containing milk\n'}


{'id': 'HP_0025214', 'url': 'http://purl.obolibrary.org/obo/HP_0025214', 'lbl': 'Triggered by heat', 'desc': 'label: Triggered by heat\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to heat.\nsynonyms :Heat triggered symptoms; Triggered by heat\n'}


{'id': 'HP_0025215', 'url': 'http://purl.obolibrary.org/obo/HP_0025215', 'lbl': 'Triggered by febrile illness', 'desc': 'label: Triggered by febrile illness\ndefinition : Applies to a sign or symptom that is provoked or brought about by febrile illness.\nsynonyms :Febrile illness triggered symptoms; Triggered by fever\n'}


{'id': 'HP_0025216', 'url': 'http://purl.obolibrary.org/obo/HP_0025216', 'lbl': 'Triggered by heavy meal', 'desc': 'label: Triggered by heavy meal\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating large quantities of food, for instance, by a heavy meal.\nsynonyms :Heavy meal triggered symptoms; Triggered by overeating\n'}


{'id': 'HP_0025217', 'url': 'http://purl.obolibrary.org/obo/HP_0025217', 'lbl': 'Triggered by high-fat diet', 'desc': 'label: Triggered by high-fat diet\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating a diet high in lipids.\nsynonyms :High-fat diet triggered symptoms; Triggered by high-fat diet\n'}


{'id': 'HP_0025218', 'url': 'http://purl.obolibrary.org/obo/HP_0025218', 'lbl': 'Triggered by hyperventilation', 'desc': 'label: Triggered by hyperventilation\ndefinition : Applies to a sign or symptom that is provoked or brought about by excessively rapid and deep breathing.\nsynonyms :Hyperventilation triggered symptoms; Triggered by hyperventilation\n'}


{'id': 'HP_0025219', 'url': 'http://purl.obolibrary.org/obo/HP_0025219', 'lbl': 'Triggered by vaccination', 'desc': 'label: Triggered by vaccination\ndefinition : Applies to a sign or symptom that is provoked or brought about by a vaccination.\nsynonyms :Triggered by immunisation; Triggered by immunization; Triggered by vaccination; Vaccination triggered symptoms\n'}


{'id': 'HP_0025220', 'url': 'http://purl.obolibrary.org/obo/HP_0025220', 'lbl': 'Triggered by menstruation', 'desc': 'label: Triggered by menstruation\ndefinition : Applies to a sign or symptom that is provoked or brought about by menstruation in a female.\nsynonyms :Menstruation triggered symptoms; Triggered by monthly period; Triggered by period\n'}


{'id': 'HP_0025221', 'url': 'http://purl.obolibrary.org/obo/HP_0025221', 'lbl': 'Triggered by pregnancy', 'desc': 'label: Triggered by pregnancy\ndefinition : Applies to a sign or symptom that is provoked or brought about by pregnancy in a female.\nsynonyms :Pregnancy triggered symptoms; Triggered by pregnancy\n'}


{'id': 'HP_0025222', 'url': 'http://purl.obolibrary.org/obo/HP_0025222', 'lbl': 'Triggered by sleep deprivation', 'desc': 'label: Triggered by sleep deprivation\ndefinition : Applies to a sign or symptom that is provoked or brought about by a lack of sufficient sleep.\nsynonyms :Sleep deprivation triggered symptoms; Triggered by sleep deprivation\n'}


{'id': 'HP_0025223', 'url': 'http://purl.obolibrary.org/obo/HP_0025223', 'lbl': 'Triggered by smoking', 'desc': 'label: Triggered by smoking\ndefinition : Applies to a sign or symptom that is provoked or brought about by smoking.\nsynonyms :Smoking triggered symptoms; Triggered by cigarette consumption; Triggered by smoking; Triggered by tobacco use\n'}


{'id': 'HP_0025224', 'url': 'http://purl.obolibrary.org/obo/HP_0025224', 'lbl': 'Triggered by sodium ingestion', 'desc': 'label: Triggered by sodium ingestion\ndefinition : Applies to a sign or symptom that is provoked or brought about by eating or drinking sodium.\nsynonyms :Sodium ingestion triggered symptoms; Sodium intake triggered attacks; Triggered by Na ingestion; Triggered by Na+ ingestion; Triggered by sodium intake; Triggered by salt ingestion\n'}


{'id': 'HP_0025225', 'url': 'http://purl.obolibrary.org/obo/HP_0025225', 'lbl': 'Triggered by sound', 'desc': 'label: Triggered by sound\ndefinition : Applies to a sign or symptom that is provoked or brought about by exposure to sound or noise.\nsynonyms :Sound triggered symptoms; Triggered by sound\n'}


{'id': 'HP_0025226', 'url': 'http://purl.obolibrary.org/obo/HP_0025226', 'lbl': 'Triggered by stress', 'desc': 'label: Triggered by stress\ndefinition : Applies to a sign or symptom that is provoked or brought about by a physical, mental, or emotional factor associated with bodily or mental tension.\nsynonyms :Stress triggered symptoms; Triggered by stress\n'}


{'id': 'HP_0025227', 'url': 'http://purl.obolibrary.org/obo/HP_0025227', 'lbl': 'Triggered by excitement', 'desc': 'label: Triggered by excitement\ndefinition : Applies to a sign or symptom that is provoked or brought about by a a state of excitement or by being startled.\nsynonyms :Excitement triggered symptoms; Triggered by excitement; Triggered by startle\n'}


{'id': 'HP_0025228', 'url': 'http://purl.obolibrary.org/obo/HP_0025228', 'lbl': 'Triggered by sudden movement', 'desc': 'label: Triggered by sudden movement\ndefinition : Applies to a sign or symptom that is provoked or brought about by a sudden movement.\nsynonyms :Kinesigenic; Sudden movement triggered symptoms; Triggered by sudden movement\n'}


{'id': 'HP_0025229', 'url': 'http://purl.obolibrary.org/obo/HP_0025229', 'lbl': 'Triggered by vestibular stimulation', 'desc': 'label: Triggered by vestibular stimulation\ndefinition : Applies to a sign or symptom that is provoked or brought about by vestibular stimulation, including head turning, cold calorics, postural changes, or rotating chair.\nsynonyms :Vestibular stimulation triggered attacks; Vestibular stimulation triggered symptoms\n'}


{'id': 'HP_0025230', 'url': 'http://purl.obolibrary.org/obo/HP_0025230', 'lbl': 'Tendonitis', 'desc': 'label: Tendonitis\ndefinition : Inflammation of a tendon.\nsynonyms :Teninitis\n'}


{'id': 'HP_0025231', 'url': 'http://purl.obolibrary.org/obo/HP_0025231', 'lbl': 'Abnormal synovial bursa morphology', 'desc': 'label: Abnormal synovial bursa morphology\ndefinition : A structural anomaly of a synovial bursa.\nsynonyms :Abnormality of synovial bursa morphology\n'}


{'id': 'HP_0025232', 'url': 'http://purl.obolibrary.org/obo/HP_0025232', 'lbl': 'Bursitis', 'desc': 'label: Bursitis\ndefinition : Inflammation of a synovial bursa.\nsynonyms :\n'}


{'id': 'HP_0025233', 'url': 'http://purl.obolibrary.org/obo/HP_0025233', 'lbl': 'Sleep paralysis', 'desc': 'label: Sleep paralysis\ndefinition : An inability to move the body at sleep onset or upon awakening from sleep lasting seconds to a few minutes.\nsynonyms :\n'}


{'id': 'HP_0025234', 'url': 'http://purl.obolibrary.org/obo/HP_0025234', 'lbl': 'Parasomnia', 'desc': 'label: Parasomnia\ndefinition : An undesirable physical event or experience that occurs during entry into sleep, during sleep, or during arousal from sleep.\nsynonyms :\n'}


{'id': 'HP_0025235', 'url': 'http://purl.obolibrary.org/obo/HP_0025235', 'lbl': 'Non-rapid eye movement parasomnia', 'desc': 'label: Non-rapid eye movement parasomnia\ndefinition : A parasomnia that occurs in non-rapid eye movement (NREM) sleep. This refers to a disorder of arousal that occurs during slow-wave sleep (ie, NREM stage 3 sleep).\nsynonyms :NREM parasomnia\n'}


{'id': 'HP_0025236', 'url': 'http://purl.obolibrary.org/obo/HP_0025236', 'lbl': 'Somnambulism', 'desc': 'label: Somnambulism\ndefinition : Ambulation or other complex motor behaviors after getting out of bed in a sleep-like state. During sleepwalking episodes, the sonambulating individual appears confused or dazed, the eyes are usually open, and he or she might mumble or give inappropriate answers to questions, or occasionally appear agitated.\nsynonyms :Sleep walking\n'}


{'id': 'HP_0025237', 'url': 'http://purl.obolibrary.org/obo/HP_0025237', 'lbl': 'Confusional arousal', 'desc': 'label: Confusional arousal\ndefinition : A nocturnal episode characterized by disorientation, grogginess, and, at times, substantial agitation upon awakening from slow-wave sleep or following forced awakenings. These characteristics might present as agitation, crying or moaning, disorientation, and particularly slow mentation on arousal from sleep (i.e., sleep inertia). The duration of episodes is typically 5 to 15 min but they might last up to several hours.\nsynonyms :\n'}


{'id': 'HP_0025238', 'url': 'http://purl.obolibrary.org/obo/HP_0025238', 'lbl': 'Foot pain', 'desc': 'label: Foot pain\ndefinition : An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the foot.\nsynonyms :Foot pain\n'}


{'id': 'HP_0025239', 'url': 'http://purl.obolibrary.org/obo/HP_0025239', 'lbl': 'Subhyaloid hemorrhage', 'desc': 'label: Subhyaloid hemorrhage\ndefinition : A localized detachment of the vitreous from the retina due to the accumulation of blood. When localized in the macular area, it results in sudden profound loss of vision. Subhyaloid premacular hemorrhage is typically characterized by a circumscribed, round or dumb-bell shaped, bright red mound of blood beneath the internal limiting membrane (ILM) or between the ILM and hyaloid face, in or near to the central macular area.\nsynonyms :Subhyaloid haemorrhage; Subhyaloid heme\n'}


{'id': 'HP_0025240', 'url': 'http://purl.obolibrary.org/obo/HP_0025240', 'lbl': 'Preretinal hemorrhage', 'desc': 'label: Preretinal hemorrhage\ndefinition : An accumulation of blood between the neurosensory retina and the retinal pigment epithelium (RPE) arising from the choroidal or retinal circulation.\nsynonyms :Preretinal haemorrhage; Preretinal heme\n'}


{'id': 'HP_0025241', 'url': 'http://purl.obolibrary.org/obo/HP_0025241', 'lbl': 'Flame-shaped retinal hemorrhage', 'desc': 'label: Flame-shaped retinal hemorrhage\ndefinition : A type of retinal hemorrhage that is located within the nerve fiber layer (NFL) of the retina and that exhibits a characteristic flame shape which results from constraints by the structure of the NFL (axons of the ganglion cells).\nsynonyms :Feathered retinal heme; Flame-shaped retinal haemorrhage; Linear retina heme\n'}


{'id': 'HP_0025242', 'url': 'http://purl.obolibrary.org/obo/HP_0025242', 'lbl': 'Dot-and-blot retinal hemorrhage', 'desc': "label: Dot-and-blot retinal hemorrhage\ndefinition : Accumulation of blood located in the retina's inner nuclear and outer plexiform layers, and having a dot-like or blot-like shape. THe shape results from intraretinal compression, restricting the hemorrhages within a specific location.\nsynonyms :Dot-and-blot retinal haemorrhage; Round retinal heme\n"}


{'id': 'HP_0025243', 'url': 'http://purl.obolibrary.org/obo/HP_0025243', 'lbl': 'Subretinal hemorrhage', 'desc': 'label: Subretinal hemorrhage\ndefinition : Accumulation of blood located beneath the neurosensory retina in the space between the neurosensory retina and the retinal pigment epithelium.\nsynonyms :Subretinal haemorrhage; Subretinal heme\n'}


{'id': 'HP_0025244', 'url': 'http://purl.obolibrary.org/obo/HP_0025244', 'lbl': 'Subretinal pigment epithelium hemorrhage', 'desc': "label: Subretinal pigment epithelium hemorrhage\ndefinition : An accumulation of blood located between the retinal pigment epithelium (RPE) and Bruch's membrane.\nsynonyms :Subretinal pigment epithelium haemorrhage\n"}


{'id': 'HP_0025245', 'url': 'http://purl.obolibrary.org/obo/HP_0025245', 'lbl': 'Cutaneous cyst', 'desc': 'label: Cutaneous cyst\ndefinition : A hollow mass located in the skin that is surrounded by an epithelium-lined wall and is well demarcated from the adjacent tissue. Cysts are often said to be sac-like and may contain serous liquid or semisolid material.\nsynonyms :\n'}


{'id': 'HP_0025246', 'url': 'http://purl.obolibrary.org/obo/HP_0025246', 'lbl': 'Trichilemmal cyst', 'desc': 'label: Trichilemmal cyst\ndefinition : Nontender, round and firm, but slightly compressible, intradermal or subcutaneous cyst measuring 0.5-5 cm in diameter. Trichilemmal cysts are acquired rather than congenital, and tend to appear on the scalp rather than the face, and to be intradermal rather than subcutaneous.\nsynonyms :Pilar cyst\n'}


{'id': 'HP_0025247', 'url': 'http://purl.obolibrary.org/obo/HP_0025247', 'lbl': 'Dermoid cyst', 'desc': 'label: Dermoid cyst\ndefinition : A congenital subcutaneous cyst that arises from entrapment of skin along the lines of embryonic fusion. In contrast to epidermal cysts, dermoid cysts tend to contain various adnexal structures such as hair, sebaceous, eccrine or apocrine glands. Dermoid cysts are present at birth, and are indolent, firm, deep, subcutaneous nodules. They are often located on the head and neck, and rarely in the anogenital area. Dermoid cysts are\nslowly progressive and can grow to a size of 1 to 4 cm.\nsynonyms :\n'}


{'id': 'HP_0025248', 'url': 'http://purl.obolibrary.org/obo/HP_0025248', 'lbl': 'Eruptive vellus hair cyst', 'desc': 'label: Eruptive vellus hair cyst\ndefinition : A cutaneous cyst that is small (one or two millimeters in diameter) and painless, presenting as a follicular papule that usually is skin colored but may have a reddish or brownish tinge.\nsynonyms :\n'}


{'id': 'HP_0025249', 'url': 'http://purl.obolibrary.org/obo/HP_0025249', 'lbl': 'Comedo', 'desc': 'label: Comedo\ndefinition : A clogged cutaneous sebaceous follicle, which is a cutaneous gland that secretes sebum (usually into a hair follicle).\nsynonyms :\n'}


{'id': 'HP_0025250', 'url': 'http://purl.obolibrary.org/obo/HP_0025250', 'lbl': 'Closed comedo', 'desc': 'label: Closed comedo\ndefinition : A comedo in which the top of the pore is not stretched open and thus does not expose the clogged portion (which would appear black), hence the name whitehead.\nsynonyms :Whitehead\n'}


{'id': 'HP_0025251', 'url': 'http://purl.obolibrary.org/obo/HP_0025251', 'lbl': 'Open comedo', 'desc': 'label: Open comedo\ndefinition : A comedo in which the part of the pore at the surface of the skin is stretched and open, exposing the contents of the comedo, which appear black.\nsynonyms :Blackhead\n'}


{'id': 'HP_0025252', 'url': 'http://purl.obolibrary.org/obo/HP_0025252', 'lbl': 'Geographic tongue', 'desc': 'label: Geographic tongue\ndefinition : An anomaly of the tongue characterized by loss (atrophy) of filiform papillae of the tongue, leaving areas of erythema (redness), surrounded by a serpiginous, white, hyperkeratotic border. The name geographic tongue refers to an appearance that is said to be similar to a map.\nsynonyms :Annulus migrans; Benign migratory glossitis; Glossitis areata exfoliativa; Lingual erythema migrans; Wandering rash of the tongue\n'}


{'id': 'HP_0025253', 'url': 'http://purl.obolibrary.org/obo/HP_0025253', 'lbl': 'Claustrophobia', 'desc': 'label: Claustrophobia\ndefinition : An abnormal fear of being in a closed or narrow space with no escape.\nsynonyms :\n'}


{'id': 'HP_0025254', 'url': 'http://purl.obolibrary.org/obo/HP_0025254', 'lbl': 'Ameliorated by', 'desc': 'label: Ameliorated by\ndefinition : An ameliorating factor is defined as an external factor that leads to a sign or symptom that is already present improving or becoming more bearable\nsynonyms :Improved by\n'}


{'id': 'HP_0025255', 'url': 'http://purl.obolibrary.org/obo/HP_0025255', 'lbl': 'Ameliorated by pregnancy', 'desc': 'label: Ameliorated by pregnancy\ndefinition : Applies to a sign or symptom that is improved or made more bearable by pregnancy in a female.\nsynonyms :Pregnancy relieves symptoms\n'}


{'id': 'HP_0025256', 'url': 'http://purl.obolibrary.org/obo/HP_0025256', 'lbl': 'Ameliorated by heat', 'desc': 'label: Ameliorated by heat\ndefinition : Applies to a sign or symptom that is improved or made more bearable by heat (including fever).\nsynonyms :Heat improves condition; Heat improves symptom; Fever improves condition\n'}


{'id': 'HP_0025257', 'url': 'http://purl.obolibrary.org/obo/HP_0025257', 'lbl': 'Ameliorated by carbohydrate ingestion', 'desc': 'label: Ameliorated by carbohydrate ingestion\ndefinition : Applies to a sign or symptom that is improved or made more bearable by eating or drinking carbohydrates including glucose (sugar).\nsynonyms :\n'}


{'id': 'HP_0025258', 'url': 'http://purl.obolibrary.org/obo/HP_0025258', 'lbl': 'Stiff neck', 'desc': 'label: Stiff neck\ndefinition : A sensation of tightness in the neck when attempting to move it, especially after a period of inactivity. Neck stiffness often involves soreness and difficulty moving the neck, especially when trying to turn the head to the side.\nsynonyms :Neck stiffness; Stiff neck\n'}


{'id': 'HP_0025259', 'url': 'http://purl.obolibrary.org/obo/HP_0025259', 'lbl': 'Stiff elbow', 'desc': 'label: Stiff elbow\ndefinition : A sensation of tightness in the elbow joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Elbow stiffness; Stiff elbow\n'}


{'id': 'HP_0025260', 'url': 'http://purl.obolibrary.org/obo/HP_0025260', 'lbl': 'Stiff wrist', 'desc': 'label: Stiff wrist\ndefinition : A sensation of tightness in the wrist joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Stiff wrist; Wrist stiffness\n'}


{'id': 'HP_0025261', 'url': 'http://purl.obolibrary.org/obo/HP_0025261', 'lbl': 'Stiff finger', 'desc': 'label: Stiff finger\ndefinition : A sensation of tightness in a finger joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Finger stiffness; Stiff finger\n'}


{'id': 'HP_0025262', 'url': 'http://purl.obolibrary.org/obo/HP_0025262', 'lbl': 'Stiff hip', 'desc': 'label: Stiff hip\ndefinition : A sensation of tightness in the hip joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Hip stiffness; Stiff hip\n'}


{'id': 'HP_0025263', 'url': 'http://purl.obolibrary.org/obo/HP_0025263', 'lbl': 'Stiff knee', 'desc': 'label: Stiff knee\ndefinition : A sensation of tightness in the knee joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Knee stiffness; Stiff knee\n'}


{'id': 'HP_0025264', 'url': 'http://purl.obolibrary.org/obo/HP_0025264', 'lbl': 'Stiff ankle', 'desc': 'label: Stiff ankle\ndefinition : A sensation of tightness in the ankle joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Ankle stiffness; Stiff ankle\n'}


{'id': 'HP_0025265', 'url': 'http://purl.obolibrary.org/obo/HP_0025265', 'lbl': 'Stiff toe', 'desc': 'label: Stiff toe\ndefinition : A sensation of tightness in a toe joint when attempting to move it, especially after a period of inactivity.\nsynonyms :Stiff toe; Toe stiffness\n'}


{'id': 'HP_0025266', 'url': 'http://purl.obolibrary.org/obo/HP_0025266', 'lbl': 'obsolete Cervical osteoarthritis', 'desc': 'label: obsolete Cervical osteoarthritis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025267', 'url': 'http://purl.obolibrary.org/obo/HP_0025267', 'lbl': 'Snoring', 'desc': 'label: Snoring\ndefinition : Deep, noisy breathing during sleep accompanied by hoarse or harsh sounds caused by the vibration of respiratory structures (especially the soft palate) resulting in sound due to obstructed air movement during breathing while sleeping.\nsynonyms :Snore; Snores; Snoring symptoms\n'}


{'id': 'HP_0025268', 'url': 'http://purl.obolibrary.org/obo/HP_0025268', 'lbl': 'Stuttering', 'desc': 'label: Stuttering\ndefinition : Disruptions in the production of speech sounds, with involuntary repetitions of words or parts of words, prolongations of speech sounds, or complete blockage of speech production for several seconds.\nsynonyms :Stammering; Stuttering\n'}


{'id': 'HP_0025269', 'url': 'http://purl.obolibrary.org/obo/HP_0025269', 'lbl': 'Panic attack', 'desc': 'label: Panic attack\ndefinition : A sudden episode of intense fear in a situation in which there is no danger or apparent cause.\nsynonyms :Panic attack\n'}


{'id': 'HP_0025270', 'url': 'http://purl.obolibrary.org/obo/HP_0025270', 'lbl': 'Abnormal esophagus physiology', 'desc': 'label: Abnormal esophagus physiology\ndefinition : Any physiological abnormality of the esophagus.\nsynonyms :Abnormality of esophagus physiology; Abnormality of oesophagus physiology; Functional abnormality of the esophagus; Functional abnormality of the oesophagus\n'}


{'id': 'HP_0025271', 'url': 'http://purl.obolibrary.org/obo/HP_0025271', 'lbl': 'Esophageal spasms', 'desc': 'label: Esophageal spasms\ndefinition : Involuntary contractions of the esophagus that are irregular, uncoordinated, and painful.\nsynonyms :\n'}


{'id': 'HP_0025272', 'url': 'http://purl.obolibrary.org/obo/HP_0025272', 'lbl': 'Melasma', 'desc': 'label: Melasma\ndefinition : Symmetrical, blotchy, brownish facial pigmentation.\nsynonyms :Chloasma; Facial melanosis\n'}


{'id': 'HP_0025273', 'url': 'http://purl.obolibrary.org/obo/HP_0025273', 'lbl': 'Achilles tendonitis', 'desc': 'label: Achilles tendonitis\ndefinition : Inflammation of the Achilles tendon.\nsynonyms :\n'}


{'id': 'HP_0025274', 'url': 'http://purl.obolibrary.org/obo/HP_0025274', 'lbl': 'Ovarian dermoid cyst', 'desc': 'label: Ovarian dermoid cyst\ndefinition : An cystic ovarian teratoma composed of dermal and epidermal elements and containing tissue components including hair, teeth, bone, thyroid, and others.\nsynonyms :Mature cystic ovarian teratoma\n'}


{'id': 'HP_0025275', 'url': 'http://purl.obolibrary.org/obo/HP_0025275', 'lbl': 'Lateral', 'desc': 'label: Lateral\ndefinition : Applies to an abnormality that is located farther from the median plane or midline of the body or of the referenced structure.\nsynonyms :\n'}


{'id': 'HP_0025276', 'url': 'http://purl.obolibrary.org/obo/HP_0025276', 'lbl': 'Abnormality of skin adnexa physiology', 'desc': 'label: Abnormality of skin adnexa physiology\ndefinition : Any functional anomaly of the skin adnexa (skin appendages), which are specialized skin structures located within the dermis and focally within the subcutaneous fatty tissue, comprising three histologically distinct structures: (1) the pilosebaceous unit (hair follicle and sebaceous glands); (2) the eccrine sweat glands; and (3) the apocrine glands.\nsynonyms :\n'}


{'id': 'HP_0025277', 'url': 'http://purl.obolibrary.org/obo/HP_0025277', 'lbl': 'Gustatory sweating', 'desc': 'label: Gustatory sweating\ndefinition : Hyperhidrosis that occurs with gustatory stimulation (e.g., moisture on face from sweating that occurs after eating).\nsynonyms :\n'}


{'id': 'HP_0025278', 'url': 'http://purl.obolibrary.org/obo/HP_0025278', 'lbl': 'Cold-induced sweating', 'desc': 'label: Cold-induced sweating\ndefinition : Sweating provoked by cold temperature rather than by heat.\nsynonyms :\n'}


{'id': 'HP_0025279', 'url': 'http://purl.obolibrary.org/obo/HP_0025279', 'lbl': 'Migratory', 'desc': 'label: Migratory\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025280', 'url': 'http://purl.obolibrary.org/obo/HP_0025280', 'lbl': 'Pain characteristic', 'desc': 'label: Pain characteristic\ndefinition : A pain characteristic is defined as a subjective category or type of pain.\nsynonyms :\n'}


{'id': 'HP_0025281', 'url': 'http://purl.obolibrary.org/obo/HP_0025281', 'lbl': 'Sharp', 'desc': 'label: Sharp\ndefinition : Applied to pain that is described as sharp, i.e., sudden and severe.\nsynonyms :\n'}


{'id': 'HP_0025282', 'url': 'http://purl.obolibrary.org/obo/HP_0025282', 'lbl': 'Dull', 'desc': 'label: Dull\ndefinition : Applied to pain that is dull, i.e., not severe but that continues over a long period of time.\nsynonyms :Dull pain\n'}


{'id': 'HP_0025283', 'url': 'http://purl.obolibrary.org/obo/HP_0025283', 'lbl': 'Tender', 'desc': 'label: Tender\ndefinition : Applied to pain that is tender, i.e., elicited by touching the affected body part.\nsynonyms :\n'}


{'id': 'HP_0025284', 'url': 'http://purl.obolibrary.org/obo/HP_0025284', 'lbl': 'Sleep-interrupting', 'desc': 'label: Sleep-interrupting\ndefinition : Applied to pain that wakes the affecting individual from sleep.\nsynonyms :\n'}


{'id': 'HP_0025285', 'url': 'http://purl.obolibrary.org/obo/HP_0025285', 'lbl': 'Aggravated by', 'desc': 'label: Aggravated by\ndefinition : An aggravating factor is defined as an external factor that leads to a sign or symptom that is already present getting worse or becoming more severe.\nsynonyms :Exacerbated by\n'}


{'id': 'HP_0025286', 'url': 'http://purl.obolibrary.org/obo/HP_0025286', 'lbl': 'Aggravated by activity', 'desc': 'label: Aggravated by activity\ndefinition : Applied to a sign or symptom that is aggravated by activity, exertion, or exercise.\nsynonyms :Aggravated by exercise; Aggravated by exertion; Worse with activity; Worsened by activity\n'}


{'id': 'HP_0025287', 'url': 'http://purl.obolibrary.org/obo/HP_0025287', 'lbl': 'Axial', 'desc': 'label: Axial\ndefinition : Applies to an abnormality that is situated in the central part of the body, in the head and trunk as distinguished from the limbs.\nsynonyms :\n'}


{'id': 'HP_0025289', 'url': 'http://purl.obolibrary.org/obo/HP_0025289', 'lbl': 'Cervical lymphadenopathy', 'desc': 'label: Cervical lymphadenopathy\ndefinition : Enlarged lymph nodes in the neck.\nsynonyms :Swollen lymph nodes in the neck\n'}


{'id': 'HP_0025290', 'url': 'http://purl.obolibrary.org/obo/HP_0025290', 'lbl': 'Upper-body predominance', 'desc': 'label: Upper-body predominance\ndefinition : Applies to an abnormality that affects the arms, trunk, head more than the legs.\nsynonyms :\n'}


{'id': 'HP_0025291', 'url': 'http://purl.obolibrary.org/obo/HP_0025291', 'lbl': 'Lower-body predominance', 'desc': 'label: Lower-body predominance\ndefinition : Applies to an abnormality that affects the legs more than the arms, trunk, head.\nsynonyms :\n'}


{'id': 'HP_0025292', 'url': 'http://purl.obolibrary.org/obo/HP_0025292', 'lbl': 'Acral', 'desc': 'label: Acral\ndefinition : Applies to an abnormality that affects the distal portions of limbs (hand, foot) and head (ears, nose).\nsynonyms :\n'}


{'id': 'HP_0025293', 'url': 'http://purl.obolibrary.org/obo/HP_0025293', 'lbl': 'Distributed along Blaschko lines', 'desc': 'label: Distributed along Blaschko lines\ndefinition : Applies to an abnormality whose localization corresponds to the lines of Blaschko, which correspond to the lineage of epithelia cells. Blaschko lines are normally invisible but may become apparent with certain skin diseases and then can be seen to be distributed in lines horizontal to the body.\nsynonyms :\n'}


{'id': 'HP_0025294', 'url': 'http://purl.obolibrary.org/obo/HP_0025294', 'lbl': 'Dermatomal', 'desc': 'label: Dermatomal\ndefinition : Applies to an abnormality whose localization corresponds to the dermatomes, i.e., the nerve root distribution.\nsynonyms :Radicular\n'}


{'id': 'HP_0025295', 'url': 'http://purl.obolibrary.org/obo/HP_0025295', 'lbl': 'Herpetiform', 'desc': 'label: Herpetiform\ndefinition : Applies to an abnormality whose distribution and appearance resembles that of the grouped umbilicated vesicles seen in herpes simplex and herpes zoster infections.\nsynonyms :\n'}


{'id': 'HP_0025296', 'url': 'http://purl.obolibrary.org/obo/HP_0025296', 'lbl': 'Morbilliform', 'desc': 'label: Morbilliform\ndefinition : Applies to an abnormality whose distribution and appearance resembles that of measles, i.e., maculopapular lesions that are red and roughly 2 to 10 mm in diameter and may be partially confluent.\nsynonyms :\n'}


{'id': 'HP_0025297', 'url': 'http://purl.obolibrary.org/obo/HP_0025297', 'lbl': 'Prolonged', 'desc': 'label: Prolonged\ndefinition : Applied to an abnormality whose duration is extended over a longer period of time than is expected or usual (e.g., prolonged fever lasts longer than one usually sees with an infection).\nsynonyms :\n'}


{'id': 'HP_0025300', 'url': 'http://purl.obolibrary.org/obo/HP_0025300', 'lbl': 'Malar rash', 'desc': 'label: Malar rash\ndefinition : An erythematous (red), flat facial rash that affects the skin in the malar area (over the cheekbones) and extends over the bridge of the nose.\nsynonyms :Butterfly rash; Cheekbone rash\n'}


{'id': 'HP_0025301', 'url': 'http://purl.obolibrary.org/obo/HP_0025301', 'lbl': 'Nocturnal', 'desc': 'label: Nocturnal\ndefinition : Applies to an abnormality that occurs in or is exacerbated during the night.\nsynonyms :\n'}


{'id': 'HP_0025302', 'url': 'http://purl.obolibrary.org/obo/HP_0025302', 'lbl': 'Diurnal', 'desc': 'label: Diurnal\ndefinition : Applies to a sign, symptom, or other abnormality that occurs in or is exacerbated in the day time.\nsynonyms :\n'}


{'id': 'HP_0025303', 'url': 'http://purl.obolibrary.org/obo/HP_0025303', 'lbl': 'Episodic', 'desc': 'label: Episodic\ndefinition : Applied to a sign, symptom, or other manifestation that occurs multiple times at usually irregular intervals. The occurences are separated by an interval in which the sign, symptom, or manifestation is not present.\nsynonyms :Now and then\n'}


{'id': 'HP_0025304', 'url': 'http://purl.obolibrary.org/obo/HP_0025304', 'lbl': 'Periodic', 'desc': 'label: Periodic\ndefinition : Applies to a sign, symptom, or other manifestation that recurs with a fixed time interval, i.e., the symptom-free periods are always of the same length.\nsynonyms :Cyclic; Cyclical\n'}


{'id': 'HP_0025305', 'url': 'http://purl.obolibrary.org/obo/HP_0025305', 'lbl': 'Quotidian', 'desc': 'label: Quotidian\ndefinition : Applies to a sign, symptom, or other manifestation that is episodic with a fixed time interval of one day (24 hours).\nsynonyms :\n'}


{'id': 'HP_0025306', 'url': 'http://purl.obolibrary.org/obo/HP_0025306', 'lbl': 'Acute emergence over minutes', 'desc': 'label: Acute emergence over minutes\ndefinition : Acute appearance of disease manifestations in a period of minutes.\nsynonyms :\n'}


{'id': 'HP_0025307', 'url': 'http://purl.obolibrary.org/obo/HP_0025307', 'lbl': 'Acute emergence over hours', 'desc': 'label: Acute emergence over hours\ndefinition : Acute appearance of disease manifestations in a period of hours.\nsynonyms :\n'}


{'id': 'HP_0025308', 'url': 'http://purl.obolibrary.org/obo/HP_0025308', 'lbl': 'Acute emergence over days', 'desc': 'label: Acute emergence over days\ndefinition : Acute appearance of disease manifestations in a period of days.\nsynonyms :\n'}


{'id': 'HP_0025309', 'url': 'http://purl.obolibrary.org/obo/HP_0025309', 'lbl': 'Abnormal pupil shape', 'desc': 'label: Abnormal pupil shape\ndefinition : A deviation from the normal circular shape of the pupil\nsynonyms :Irregular pupil\n'}


{'id': 'HP_0025310', 'url': 'http://purl.obolibrary.org/obo/HP_0025310', 'lbl': 'Oval pupil', 'desc': 'label: Oval pupil\ndefinition : An abnormal pupil shape that is elliptical, i.e., egg-like.\nsynonyms :\n'}


{'id': 'HP_0025311', 'url': 'http://purl.obolibrary.org/obo/HP_0025311', 'lbl': 'Anterior chamber cyst', 'desc': 'label: Anterior chamber cyst\ndefinition : A closed sac, having a distinct membrane and division compared to the nearby tissue located within the anterior chamber. The sac that may contain air, fluids, or semi-solid material.\nsynonyms :\n'}


{'id': 'HP_0025312', 'url': 'http://purl.obolibrary.org/obo/HP_0025312', 'lbl': 'Esophoria', 'desc': 'label: Esophoria\ndefinition : A form of strabismus with both eyes turned inward to a relatively mild degree, usually defined as less than 10 prism diopters.\nsynonyms :\n'}


{'id': 'HP_0025313', 'url': 'http://purl.obolibrary.org/obo/HP_0025313', 'lbl': 'Exophoria', 'desc': 'label: Exophoria\ndefinition : A form of strabismus with one or both eyes deviated outward to a milder degree than with exotropia.\nsynonyms :\n'}


{'id': 'HP_0025314', 'url': 'http://purl.obolibrary.org/obo/HP_0025314', 'lbl': 'Choroidal nevus', 'desc': 'label: Choroidal nevus\ndefinition : A benign, flat or slightly elevated melanocytic lesions of the posterior uveawith clearly defined margins. Choroidal nevi tend they remain stable in size, and to display features such as overlying drusen as well as retinal pigment epithelial atrophy, hyperplasia or fibrous metaplasia.\nsynonyms :\n'}


{'id': 'HP_0025315', 'url': 'http://purl.obolibrary.org/obo/HP_0025315', 'lbl': 'Exacerbated by head trauma', 'desc': 'label: Exacerbated by head trauma\ndefinition : Applies to a sign or symptom that is worsened, aggravated, or exacerbated by head trauma.\nsynonyms :\n'}


{'id': 'HP_0025317', 'url': 'http://purl.obolibrary.org/obo/HP_0025317', 'lbl': 'Cubitus varus', 'desc': 'label: Cubitus varus\ndefinition : A deformity of the elbow in which there is a deviation of the forearm toward the midline of the body.\nsynonyms :\n'}


{'id': 'HP_0025318', 'url': 'http://purl.obolibrary.org/obo/HP_0025318', 'lbl': 'Ovarian carcinoma', 'desc': 'label: Ovarian carcinoma\ndefinition : A malignant neoplasm originating from the surface ovarian epithelium.\nsynonyms :Ovarian epithelial cancer\n'}


{'id': 'HP_0025319', 'url': 'http://purl.obolibrary.org/obo/HP_0025319', 'lbl': 'Rubeosis iridis', 'desc': 'label: Rubeosis iridis\ndefinition : Formation of new blood vessels on the iris. The new vessels do not display the typical radially symmertic growth pattern of normal iris blood vessels, but rather appear disorganized. Rubeosis usually starts from the pupillary border with tiny tufts of dilated capillaries or red spots that can only be appreciated with high magnification.\nsynonyms :\n'}


{'id': 'HP_0025320', 'url': 'http://purl.obolibrary.org/obo/HP_0025320', 'lbl': 'Leakage of dye on fundus fluorescein angiography', 'desc': 'label: Leakage of dye on fundus fluorescein angiography\ndefinition : Leakage of fluorescein dye observed upon retinal fluorescein angiography. Areas of leakage can be appreciated as showing gradual enlargement with blurring of margins.\nsynonyms :Fluorescein leakage\n'}


{'id': 'HP_0025321', 'url': 'http://purl.obolibrary.org/obo/HP_0025321', 'lbl': 'Copper accumulation in liver', 'desc': 'label: Copper accumulation in liver\ndefinition : An anomalous build up of copper (Cu) in the liver.\nsynonyms :Liver copper accumulation\n'}


{'id': 'HP_0025322', 'url': 'http://purl.obolibrary.org/obo/HP_0025322', 'lbl': 'Venous occlusion', 'desc': 'label: Venous occlusion\ndefinition : Blockage of venous return (flow of blood from the periphery back towards the right atrium) in a vein.\nsynonyms :\n'}


{'id': 'HP_0025323', 'url': 'http://purl.obolibrary.org/obo/HP_0025323', 'lbl': 'Abnormal arterial physiology', 'desc': 'label: Abnormal arterial physiology\ndefinition : An anomaly of arterial function.\nsynonyms :\n'}


{'id': 'HP_0025324', 'url': 'http://purl.obolibrary.org/obo/HP_0025324', 'lbl': 'Arterial occlusion', 'desc': 'label: Arterial occlusion\ndefinition : Blockage of blood flow through an artery.\nsynonyms :\n'}


{'id': 'HP_0025325', 'url': 'http://purl.obolibrary.org/obo/HP_0025325', 'lbl': 'Sparse medial eyebrow', 'desc': 'label: Sparse medial eyebrow\ndefinition : Decreased density/number and/or decreased diameter of medial eyebrow hairs.\nsynonyms :Medial thinning of eyebrow\n'}


{'id': 'HP_0025326', 'url': 'http://purl.obolibrary.org/obo/HP_0025326', 'lbl': 'Retinal arterial occlusion', 'desc': 'label: Retinal arterial occlusion\ndefinition : Blockage of the retinal artery, generally associated with interruption of blood flow and oxygen delivery to the retina.\nsynonyms :Retinal artery occlusion\n'}


{'id': 'HP_0025327', 'url': 'http://purl.obolibrary.org/obo/HP_0025327', 'lbl': 'Decreased renal parenchymal thickness', 'desc': 'label: Decreased renal parenchymal thickness\ndefinition : Reduced dimension of the solid part of the kidney (parenchyma, the renal cortex and medulla) as measured from the collecting system (renal calyces and pelvis) to the border of the kidney. This measurement can be performed by measuring the thickness of the parenchyma in computed tomography scans.\nsynonyms :\n'}


{'id': 'HP_0025328', 'url': 'http://purl.obolibrary.org/obo/HP_0025328', 'lbl': 'Antepartum hemorrhage', 'desc': 'label: Antepartum hemorrhage\ndefinition : Significant maternal hemorrhage/bleed in the second half of pregnancy and prior to the birth of the baby.\nsynonyms :Antepartum haemorrhage; Prepartum haemorrhage; Prepartum hemorrhage\n'}


{'id': 'HP_0025329', 'url': 'http://purl.obolibrary.org/obo/HP_0025329', 'lbl': 'Anti-glutamic acid decarboxylase antibody positivity', 'desc': 'label: Anti-glutamic acid decarboxylase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against glutamic acid decarboxylase.\nsynonyms :Anti-GAD antibody positivity\n'}


{'id': 'HP_0025330', 'url': 'http://purl.obolibrary.org/obo/HP_0025330', 'lbl': 'Downgaze palsy', 'desc': "label: Downgaze palsy\ndefinition : A limitation of the ability to direct one's gaze below the horizontal meridian.\nsynonyms :Downgaze paresis; Supranuclear downgaze palsy\n"}


{'id': 'HP_0025331', 'url': 'http://purl.obolibrary.org/obo/HP_0025331', 'lbl': 'Upgaze palsy', 'desc': "label: Upgaze palsy\ndefinition : A limitation of the ability to direct one's gaze above the horizontal meridian.\nsynonyms :Supranuclear upgaze palsy; Upgaze paresis\n"}


{'id': 'HP_0025332', 'url': 'http://purl.obolibrary.org/obo/HP_0025332', 'lbl': 'Abnormality of foot cortical bone', 'desc': 'label: Abnormality of foot cortical bone\ndefinition : An anomaly of the outer shell (cortex) of a foot bone.\nsynonyms :Abnormality of the cortex of foot bones\n'}


{'id': 'HP_0025333', 'url': 'http://purl.obolibrary.org/obo/HP_0025333', 'lbl': 'Cortical thinning of foot bones', 'desc': 'label: Cortical thinning of foot bones\ndefinition : A reduction in the thickness of the outer shell (cortex) of foot bones.\nsynonyms :\n'}


{'id': 'HP_0025334', 'url': 'http://purl.obolibrary.org/obo/HP_0025334', 'lbl': 'Triggered by emotion', 'desc': 'label: Triggered by emotion\ndefinition : Applies to a sign or symptom that is provoked or brought about by a strong spontaneously arising mental state, reaction or feeling (emotion).\nsynonyms :Emotion triggered symptoms\n'}


{'id': 'HP_0025335', 'url': 'http://purl.obolibrary.org/obo/HP_0025335', 'lbl': 'Delayed ability to stand', 'desc': 'label: Delayed ability to stand\ndefinition : A failure to achieve the ability to stand up at an appropriate developmental stage. Most children begin to walk alone at 11 to 15 months of age. On average, children can stand while holding on at the age of 9 to 10 months, can pull up to stand and walk with one hand being held at 12 months, and can stand alone and walk well at 18 months.\nsynonyms :\n'}


{'id': 'HP_0025336', 'url': 'http://purl.obolibrary.org/obo/HP_0025336', 'lbl': 'Delayed ability to sit', 'desc': 'label: Delayed ability to sit\ndefinition : A failure to achieve the ability to sit at an appropriate developmental stage. Most children sit with support at 6 months of age and sit steadily without support at 9 months of age.\nsynonyms :\n'}


{'id': 'HP_0025337', 'url': 'http://purl.obolibrary.org/obo/HP_0025337', 'lbl': 'Red eye', 'desc': 'label: Red eye\ndefinition : A reddish appearance over the white part (sclera) of the eye ranging from a few enlarged blood vessels appearing as wiggly lines over the sclera to a bright red color completely covering to sclera.\nsynonyms :Red eye; Red eyes\n'}


{'id': 'HP_0025338', 'url': 'http://purl.obolibrary.org/obo/HP_0025338', 'lbl': 'Circumlimbal hyperemia', 'desc': 'label: Circumlimbal hyperemia\ndefinition : A ring of redness at the limbus of the eye, the border between the cornea and the sclera.\nsynonyms :Ciliary limbus; Circumlimbal hyperaemia\n'}


{'id': 'HP_0025339', 'url': 'http://purl.obolibrary.org/obo/HP_0025339', 'lbl': 'Superficial episcleral hyperemia', 'desc': 'label: Superficial episcleral hyperemia\ndefinition : Prominence of blood vessels of the superficial episcleral tissues.\nsynonyms :Superficial episcleral hypaeremia\n'}


{'id': 'HP_0025340', 'url': 'http://purl.obolibrary.org/obo/HP_0025340', 'lbl': 'Deep episcleral hyperemia', 'desc': 'label: Deep episcleral hyperemia\ndefinition : Prominence of blood vessels of the deep episcleral tissues.\nsynonyms :Deep episcleral hyperaemia\n'}


{'id': 'HP_0025341', 'url': 'http://purl.obolibrary.org/obo/HP_0025341', 'lbl': 'Corneal keratic precipitates', 'desc': 'label: Corneal keratic precipitates\ndefinition : An inflammatory cellular deposit deposited on the corneal endothelium and visible as spots on the cornea.\nsynonyms :\n'}


{'id': 'HP_0025342', 'url': 'http://purl.obolibrary.org/obo/HP_0025342', 'lbl': 'Central retinal artery occlusion', 'desc': 'label: Central retinal artery occlusion\ndefinition : Blockage of the main artery in the retina. The typical presentation is one of profound monocular visual loss.\nsynonyms :\n'}


{'id': 'HP_0025343', 'url': 'http://purl.obolibrary.org/obo/HP_0025343', 'lbl': 'Lupus anticoagulant', 'desc': 'label: Lupus anticoagulant\ndefinition : Presence of lupus anticoagulant (LA) autoantibodies. LA represent a heterogeneous group of autoantibodies, IgG, IgM, or a mixture of both classes, that interfere with standard phospholipid-based coagulant tests (this is only an in vitro phenomenon, LA do not cause reduction of coagulation in vivo). The antibodies are directed against plasma proteins which also bind to phospholipid surfaces.\nsynonyms :\n'}


{'id': 'HP_0025344', 'url': 'http://purl.obolibrary.org/obo/HP_0025344', 'lbl': 'Interlobular bile duct destruction', 'desc': 'label: Interlobular bile duct destruction\ndefinition : Damage to and obliteration of intrahepatic bile ducts (bile ducts that transport bile between the Canals of Hering and the interlobar bile ducts).\nsynonyms :\n'}


{'id': 'HP_0025345', 'url': 'http://purl.obolibrary.org/obo/HP_0025345', 'lbl': 'Abnormality of circulating beta-2-microglobulin level', 'desc': 'label: Abnormality of circulating beta-2-microglobulin level\ndefinition : A deviation from the normal concentration of beta-2-microglobulin in the blood.\nsynonyms :Abnormality of circulating B2M level; Abnormality of circulating beta2 microglobulin level; Abnormality of circulating beta2-m level; Abnormality of circulating beta2m level\n'}


{'id': 'HP_0025346', 'url': 'http://purl.obolibrary.org/obo/HP_0025346', 'lbl': 'Increased circulating beta-2-microglobulin level', 'desc': 'label: Increased circulating beta-2-microglobulin level\ndefinition : Elevated concentration of beta-2-microglobulin in the blood.\nsynonyms :Elevated circulating beta-2-microglobulin level\n'}


{'id': 'HP_0025347', 'url': 'http://purl.obolibrary.org/obo/HP_0025347', 'lbl': 'Decreased circulating beta-2-microglobulin level', 'desc': 'label: Decreased circulating beta-2-microglobulin level\ndefinition : Reduced concentration of beta-2-microglobulin in the blood.\nsynonyms :Reduced circulating beta-2-microglobulin level\n'}


{'id': 'HP_0025348', 'url': 'http://purl.obolibrary.org/obo/HP_0025348', 'lbl': 'Abnormal corneal limbus morphology', 'desc': 'label: Abnormal corneal limbus morphology\ndefinition : An anomaly of the margin of the cornea overlapped by the sclera.\nsynonyms :Abnormality of the corneal limbus\n'}


{'id': 'HP_0025349', 'url': 'http://purl.obolibrary.org/obo/HP_0025349', 'lbl': 'Limbal edema', 'desc': 'label: Limbal edema\ndefinition : Swelling of the margin of the cornea overlapped by the sclera.\nsynonyms :Limbal oedema\n'}


{'id': 'HP_0025350', 'url': 'http://purl.obolibrary.org/obo/HP_0025350', 'lbl': 'Giant conjunctival papillae', 'desc': 'label: Giant conjunctival papillae\ndefinition : Conjunctival papillae with a diameter greater than 1 millimeter. They characteristically have flattened tops which sometimes demonstrate staining with fluorescein.\nsynonyms :\n'}


{'id': 'HP_0025351', 'url': 'http://purl.obolibrary.org/obo/HP_0025351', 'lbl': 'Recurrent interdigital mycosis', 'desc': 'label: Recurrent interdigital mycosis\ndefinition : A history of repeated fungal infections located between the fingers or toes, usually manifested by scaling, maceration, and itching. The toes are more commonly affected than the fingers.\nsynonyms :Recurrent interdigital tinea\n'}


{'id': 'HP_0025352', 'url': 'http://purl.obolibrary.org/obo/HP_0025352', 'lbl': 'Typically de novo', 'desc': 'label: Typically de novo\ndefinition : Description of conditions that are exclusively or predominantly observed to display de novo variants. In some cases, this may be due to the limited reproductive fitness of affected individuals.\nsynonyms :Autosomal dominant germline de novo mutation\n'}


{'id': 'HP_0025353', 'url': 'http://purl.obolibrary.org/obo/HP_0025353', 'lbl': 'Anti-multiple nuclear dots antibody positivity', 'desc': 'label: Anti-multiple nuclear dots antibody positivity\ndefinition : A type of antinuclear antibody (ANA) positivity revealed by indirect immunofluorescence (IFL). The multiple nuclear dots (MND) pattern is immunomorphologically characterized by the staining of 3-20 dots of variable size distributed all over the cell nucleus, but sparing the nucleoli, and, in contrast to the anticentromere pattern, MND reactivity does not stain the chromosomes in mitotic cells.\nsynonyms :Anti-MND antibodies\n'}


{'id': 'HP_0025354', 'url': 'http://purl.obolibrary.org/obo/HP_0025354', 'lbl': 'Abnormal cellular phenotype', 'desc': 'label: Abnormal cellular phenotype\ndefinition : An anomaly of cellular morphology or physiology.\nsynonyms :\n'}


{'id': 'HP_0025355', 'url': 'http://purl.obolibrary.org/obo/HP_0025355', 'lbl': 'Retinal arterial macroaneurysms', 'desc': 'label: Retinal arterial macroaneurysms\ndefinition : Acquired focal dilatations of branches of the retinal artery, usually second-order retinal arterioles, that range in size from 100 to 200 micrometers in diameter. Macroaneurysms are generally located at the termporal retina and may be hemorrhagic or exudative.\nsynonyms :\n'}


{'id': 'HP_0025356', 'url': 'http://purl.obolibrary.org/obo/HP_0025356', 'lbl': 'obsolete Psychomotor retardation', 'desc': 'label: obsolete Psychomotor retardation\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025357', 'url': 'http://purl.obolibrary.org/obo/HP_0025357', 'lbl': 'Erratic myoclonus', 'desc': 'label: Erratic myoclonus\ndefinition : A type of myoclonus in which the myoclonias shift from body region to another in a random and asynchronous fashion. Erratic myoclonus can affect the face or limbs, are brief, single or repetitive, very frequent and nearly continuous.\nsynonyms :Fragmentary myoclonus\n'}


{'id': 'HP_0025358', 'url': 'http://purl.obolibrary.org/obo/HP_0025358', 'lbl': 'Uveal ectropion', 'desc': 'label: Uveal ectropion\ndefinition : Presence of iris pigment epithelium on the anterior surface of the iris.\nsynonyms :Ectropion uveae\n'}


{'id': 'HP_0025359', 'url': 'http://purl.obolibrary.org/obo/HP_0025359', 'lbl': 'Polygonal renal calices', 'desc': 'label: Polygonal renal calices\ndefinition : An abnormal polygonal shape of the calices of the kidney (which normally have a rounded or cup-shaped appearance).\nsynonyms :Polygonal calices; Polygonal-shaped calices\n'}


{'id': 'HP_0025360', 'url': 'http://purl.obolibrary.org/obo/HP_0025360', 'lbl': 'Polycalycosis', 'desc': 'label: Polycalycosis\ndefinition : Increased number of calices of the kidney.\nsynonyms :\n'}


{'id': 'HP_0025361', 'url': 'http://purl.obolibrary.org/obo/HP_0025361', 'lbl': 'Abnormality of medullary pyramid morphology', 'desc': 'label: Abnormality of medullary pyramid morphology\ndefinition : A structural anomaly of the pyramid of the adult kidney, cone-shaped structures with a broad base adjacent to the renal cortex and the narrow apex that is termed papilla.\nsynonyms :\n'}


{'id': 'HP_0025362', 'url': 'http://purl.obolibrary.org/obo/HP_0025362', 'lbl': 'Renal medullary pyramid hypoplasia', 'desc': 'label: Renal medullary pyramid hypoplasia\ndefinition : Undergrowth of the pyramid of the adult kidney, cone-shaped structures with a broad base adjacent to the renal cortex and the narrow apex that is termed papilla.\nsynonyms :Hypoplasia of the medullary pyramids\n'}


{'id': 'HP_0025363', 'url': 'http://purl.obolibrary.org/obo/HP_0025363', 'lbl': 'Glomerular endocapillary hypercellularity', 'desc': 'label: Glomerular endocapillary hypercellularity\ndefinition : Hypercellularity due to increased number of cells within glomerular capillary lumina, causing narrowing of the lumina.\nsynonyms :Endocapillary hypercellularity\n'}


{'id': 'HP_0025364', 'url': 'http://purl.obolibrary.org/obo/HP_0025364', 'lbl': 'Glomerular extracapillary hypercellularity', 'desc': 'label: Glomerular extracapillary hypercellularity\ndefinition : Hypercellularity (increased number of cells) in the renal glomerulus but external to the glomerular capillaries, i.e., in the Bowman space or more than one layer of parietal or visceral epithelial cells.\nsynonyms :Extracapillary glomerular hypercellularity; Extracapillary hypercellularity\n'}


{'id': 'HP_0025367', 'url': 'http://purl.obolibrary.org/obo/HP_0025367', 'lbl': 'Trichoepithelioma', 'desc': 'label: Trichoepithelioma\ndefinition : A benign hair follicle tumor whose tumor cells form rudimentary hair follicles but not actual hair shafts. A trichoepithelioma is usually less than one centimeter, firm, round, and shihy with yellow, pink, brown, or bluish color. They may occur multiply, usually on the face, and may gradually increase in number with age.\nsynonyms :\n'}


{'id': 'HP_0025368', 'url': 'http://purl.obolibrary.org/obo/HP_0025368', 'lbl': 'Abnormal growth plate morphology', 'desc': 'label: Abnormal growth plate morphology\ndefinition : A structural anomaly of the growth plates (epiphyseal plates), areas of cartilage located near the ends of long bones that are located between the metaphysis (widened part of the shaft of the bone) and the epiphysis (end of the bone) and in which growth occurs in the developing bone. After conclusion of bone growth, the growth plates ossify (harden into solid bone).\nsynonyms :Abnormality of growth plate morphology\n'}


{'id': 'HP_0025369', 'url': 'http://purl.obolibrary.org/obo/HP_0025369', 'lbl': 'Thick growth plates', 'desc': 'label: Thick growth plates\ndefinition : Increased thickness (dimension along the axis of the bone) of the growth plate.\nsynonyms :\n'}


{'id': 'HP_0025370', 'url': 'http://purl.obolibrary.org/obo/HP_0025370', 'lbl': 'Abnormal ossification of the sacrum', 'desc': 'label: Abnormal ossification of the sacrum\ndefinition : Abnormal bone tissue formation (ossification) affecting the sacrum.\nsynonyms :\n'}


{'id': 'HP_0025371', 'url': 'http://purl.obolibrary.org/obo/HP_0025371', 'lbl': 'Delayed ossification of the sacrum', 'desc': 'label: Delayed ossification of the sacrum\ndefinition : Formation of the sacrum bone tissue occurs later than age-adjusted norms.\nsynonyms :\n'}


{'id': 'HP_0025372', 'url': 'http://purl.obolibrary.org/obo/HP_0025372', 'lbl': 'Loud snoring', 'desc': 'label: Loud snoring\ndefinition : Particularly loud snoring, snoring at high volume.\nsynonyms :Has loud snoring; Have loud snoring; Heavy snoring; Snores loudly\n'}


{'id': 'HP_0025373', 'url': 'http://purl.obolibrary.org/obo/HP_0025373', 'lbl': 'Interictal EEG abnormality', 'desc': 'label: Interictal EEG abnormality\ndefinition : Interictal refers to a period of time between epileptic seizures. Electroencephalographic (EEG) patterns are important in the differential diagnosis of epilepsy, and the EEG is almost always abnormal during a seizure. Some persons with seizures may show EEG abnormalities between seizures, while others do not. In some cases, multiple interictal EEGs must be recorded before an abnormality is observed. In most cases the electrographic pattern of seizure onset is completely different from the activity recorded during interictal discharge.\nsynonyms :\n'}


{'id': 'HP_0025374', 'url': 'http://purl.obolibrary.org/obo/HP_0025374', 'lbl': 'Duplicated odontoid process', 'desc': 'label: Duplicated odontoid process\ndefinition : The presence of two distinct odontoid processes. The odontoid process, also known as the dens of the axis, is a protuberance of the C2 vertebral body around which the first vertebra rotates.\nsynonyms :\n'}


{'id': 'HP_0025375', 'url': 'http://purl.obolibrary.org/obo/HP_0025375', 'lbl': 'Orthotopic os odontoideum', 'desc': 'label: Orthotopic os odontoideum\ndefinition : Os odontoideum is classified into two anatomic types (orthotopic and dystopic). Os odontoideum is defined as an ossicle that consists of smooth and separate caudal portions of the odontoid process.With dystopic os odontoideum, the ossicle is located near the basion or is fused with the clivus.\nsynonyms :\n'}


{'id': 'HP_0025376', 'url': 'http://purl.obolibrary.org/obo/HP_0025376', 'lbl': 'Hyperglutaminuria', 'desc': 'label: Hyperglutaminuria\ndefinition : An increased concentration of glutamine in the urine.\nsynonyms :Glutamine high in urine; Glutaminuria\n'}


{'id': 'HP_0025377', 'url': 'http://purl.obolibrary.org/obo/HP_0025377', 'lbl': 'Triggered by exertion', 'desc': 'label: Triggered by exertion\ndefinition : Applies to a sign or symptom that is provoked or brought about by exertion or physical exercise.\nsynonyms :Exertion triggered symptoms; Triggered by physical exercise\n'}


{'id': 'HP_0025379', 'url': 'http://purl.obolibrary.org/obo/HP_0025379', 'lbl': 'Anti-thyroid peroxidase antibody positivity', 'desc': 'label: Anti-thyroid peroxidase antibody positivity\ndefinition : The presence of autoantibodies (immunoglobulins) in the serum that react against thyroid peroxidase.\nsynonyms :Anti-TPO antibody positivity; TPOAbs\n'}


{'id': 'HP_0025380', 'url': 'http://purl.obolibrary.org/obo/HP_0025380', 'lbl': 'Increased circulating androstenedione concentration', 'desc': 'label: Increased circulating androstenedione concentration\ndefinition : Increased concentration of androstenedione in the blood circulation.\nsynonyms :Increased serum androstenedione\n'}


{'id': 'HP_0025381', 'url': 'http://purl.obolibrary.org/obo/HP_0025381', 'lbl': 'Anti-pituitary antibody positivity', 'desc': 'label: Anti-pituitary antibody positivity\ndefinition : Circulating antipituitary antibodies (APA) are markers of autoimmune hypophysitis, which may cause deficient pituitary function.\nsynonyms :\n'}


{'id': 'HP_0025382', 'url': 'http://purl.obolibrary.org/obo/HP_0025382', 'lbl': 'Hypodipsia', 'desc': 'label: Hypodipsia\ndefinition : Reduced fluid intake (drinking) in a clinical situation where the plasma molarity or sodium concentration normally would induce greater fluid intake.\nsynonyms :\n'}


{'id': 'HP_0025383', 'url': 'http://purl.obolibrary.org/obo/HP_0025383', 'lbl': 'Dorsocervical fat pad', 'desc': 'label: Dorsocervical fat pad\ndefinition : An area of fat accumulation at the back of the neck in the form of a hump.\nsynonyms :Buffalo hump\n'}


{'id': 'HP_0025384', 'url': 'http://purl.obolibrary.org/obo/HP_0025384', 'lbl': 'Diet-resistant subcutaneous adipose tissue', 'desc': 'label: Diet-resistant subcutaneous adipose tissue\ndefinition : Areas of subcutanous fat tissue that are resistant to (do not respond as expected to) diet, life-style alteration, or bariatric surgery.\nsynonyms :\n'}


{'id': 'HP_0025385', 'url': 'http://purl.obolibrary.org/obo/HP_0025385', 'lbl': 'Diet-resistant subcutaneous adipose tissue below waist', 'desc': 'label: Diet-resistant subcutaneous adipose tissue below waist\ndefinition : Areas of subcutanous fat tissue below the waist that are resistant to (do not respond as expected to) diet, life-style alteration, or bariatric surgery.\nsynonyms :\n'}


{'id': 'HP_0025386', 'url': 'http://purl.obolibrary.org/obo/HP_0025386', 'lbl': 'Bitemporal hollowing', 'desc': 'label: Bitemporal hollowing\ndefinition : Depression of profile in both temporal regions.\nsynonyms :\n'}


{'id': 'HP_0025387', 'url': 'http://purl.obolibrary.org/obo/HP_0025387', 'lbl': 'Pill-rolling tremor', 'desc': 'label: Pill-rolling tremor\ndefinition : A type of resting tremor characterized by simultaneous rubbing movements of thumb and index fingers against each other.\nsynonyms :Pill rolling\n'}


{'id': 'HP_0025388', 'url': 'http://purl.obolibrary.org/obo/HP_0025388', 'lbl': 'Thyroid nodule', 'desc': 'label: Thyroid nodule\ndefinition : A nodular lesion that develops in the thyroid gland. The term "thyroid nodule" refers to any abnormal growth that forms a lump in the thyroid gland.\nsynonyms :\n'}


{'id': 'HP_0025389', 'url': 'http://purl.obolibrary.org/obo/HP_0025389', 'lbl': 'Pulmonary interstitial high-resolution computed tomography abnormality', 'desc': 'label: Pulmonary interstitial high-resolution computed tomography abnormality\ndefinition : High-resolution computed tomography (HRCT) can distinguish findings that characterize characterise interstitial lung diseases in a way not possible with other modalities.\nsynonyms :Pulmonary interstitiatial HRCT abnormality\n'}


{'id': 'HP_0025390', 'url': 'http://purl.obolibrary.org/obo/HP_0025390', 'lbl': 'Reticular pattern on pulmonary HRCT', 'desc': 'label: Reticular pattern on pulmonary HRCT\ndefinition : On pulmonary high-resolution computed tomography, reticular pattern is characterised by innumerable interlacing shadows suggesting a mesh.\nsynonyms :\n'}


{'id': 'HP_0025391', 'url': 'http://purl.obolibrary.org/obo/HP_0025391', 'lbl': 'Crazy paving pattern', 'desc': 'label: Crazy paving pattern\ndefinition : The so-called crazy paving pattern appears as thickened interlobular septa and intralobular lines superimposed on a background of ground-glass opacity, resembling irregularly shaped paving stones. The crazy-paving pattern is often sharply demarcated from more normal lung and may have a geographic outline. It was originally reported in patients with alveolar proteinosis and is also encountered in other diffuse lung diseases that affect both the interstitial and airspace compartments, such as lipoid pneumonia.\nsynonyms :Crazy paving pattern on pulmonary HRCT; Crazy-paving pattern\n'}


{'id': 'HP_0025392', 'url': 'http://purl.obolibrary.org/obo/HP_0025392', 'lbl': 'Nodular pattern on pulmonary HRCT', 'desc': 'label: Nodular pattern on pulmonary HRCT\ndefinition : A nodular pattern is characterised on pulmonary high-resolution computed tomography by the presence of numerous rounded opacities that range from 2 mm to 1 cm in diameter, with micronodules defined as smaller than 3 mm in diameter.\nsynonyms :\n'}


{'id': 'HP_0025393', 'url': 'http://purl.obolibrary.org/obo/HP_0025393', 'lbl': 'Reticulonodular pattern on pulmonary HRCT', 'desc': 'label: Reticulonodular pattern on pulmonary HRCT\ndefinition : Co-occurrence of reticular and micronodular patterns on pulmonary high-resolution computed tomography.\nsynonyms :\n'}


{'id': 'HP_0025394', 'url': 'http://purl.obolibrary.org/obo/HP_0025394', 'lbl': 'Cystic pattern on pulmonary HRCT', 'desc': 'label: Cystic pattern on pulmonary HRCT\ndefinition : On pulmonary high-resolution computed tomography, the cystic pattern is composed by well-defined, round and circumscribed air-containing parenchymal spaces with a well-defined wall and interface with normal lung. The wall of the cysts may be uniform or varied in thickness, but usually is thin (less than 2 mm) and occurs without associated emphysema.\nsynonyms :\n'}


{'id': 'HP_0025395', 'url': 'http://purl.obolibrary.org/obo/HP_0025395', 'lbl': 'Combined cystic and ground-glass pattern on pulmonary HRCT', 'desc': 'label: Combined cystic and ground-glass pattern on pulmonary HRCT\ndefinition : Co-occurrence of the cystic pattern and the ground-glass pattern on pulmonary high-resolution computed tomography,\nsynonyms :\n'}


{'id': 'HP_0025396', 'url': 'http://purl.obolibrary.org/obo/HP_0025396', 'lbl': 'Decreased attenuation pattern on pulmonary HRCT', 'desc': 'label: Decreased attenuation pattern on pulmonary HRCT\ndefinition : Areas of low density corresponding to parenchymal destruction and reduced perfusion, and attenuation of the pulmonary vasculature, as visualized on pulmonary high-resolution computed tomography.\nsynonyms :Black lung pattern on pulmonary HRCT\n'}


{'id': 'HP_0025397', 'url': 'http://purl.obolibrary.org/obo/HP_0025397', 'lbl': 'Mosaic attenuation pattern on pulmonary HRCT', 'desc': 'label: Mosaic attenuation pattern on pulmonary HRCT\ndefinition : A patchwork of intermingled areas of increased and decreased attenuation visualized on pulmonary high-resolution computed tomography.\nsynonyms :\n'}


{'id': 'HP_0025398', 'url': 'http://purl.obolibrary.org/obo/HP_0025398', 'lbl': 'Nodular-perilymphatic pattern on pulmonary HRCT', 'desc': 'label: Nodular-perilymphatic pattern on pulmonary HRCT\ndefinition : A nodular pattern on pulmonary high-resolution computed tomography that has a perilymphatic distribution.\nsynonyms :\n'}


{'id': 'HP_0025399', 'url': 'http://purl.obolibrary.org/obo/HP_0025399', 'lbl': 'Nodular-centrilobular with tree-in-bud pattern on pulmonary HRCT', 'desc': 'label: Nodular-centrilobular with tree-in-bud pattern on pulmonary HRCT\ndefinition : A nodular pattern on pulmonary high-resolution computed tomography that displays a tree-in-bud pattern, representing centrilobular branching structures that resemble a budding tree.\nsynonyms :\n'}


{'id': 'HP_0025400', 'url': 'http://purl.obolibrary.org/obo/HP_0025400', 'lbl': 'Nodular-random pattern on pulmonary HRCT', 'desc': 'label: Nodular-random pattern on pulmonary HRCT\ndefinition : A nodular pattern on pulmonary high-resolution computed tomography that has an apparently random pattern.\nsynonyms :\n'}


{'id': 'HP_0025401', 'url': 'http://purl.obolibrary.org/obo/HP_0025401', 'lbl': 'Staring gaze', 'desc': 'label: Staring gaze\ndefinition : An abnormality in which the eyes are held permanently wide open.\nsynonyms :Staring eyes\n'}


{'id': 'HP_0025402', 'url': 'http://purl.obolibrary.org/obo/HP_0025402', 'lbl': 'Square-wave jerks', 'desc': 'label: Square-wave jerks\ndefinition : Square wave jerks are saccadic eye movements which, when recorded with open eyes are considered to be a pathological sign, caused by fixation instability, and pointing to a central neurological lesion.\nsynonyms :\n'}


{'id': 'HP_0025403', 'url': 'http://purl.obolibrary.org/obo/HP_0025403', 'lbl': 'Stooped posture', 'desc': 'label: Stooped posture\ndefinition : A habitual positioning of the body with the head and upper back bent forward.\nsynonyms :\n'}


{'id': 'HP_0025404', 'url': 'http://purl.obolibrary.org/obo/HP_0025404', 'lbl': 'Abnormal visual fixation', 'desc': 'label: Abnormal visual fixation\ndefinition : Any anomaly in the process of ocular fixation, which is the maintaining of the visual gaze on a single location.\nsynonyms :\n'}


{'id': 'HP_0025405', 'url': 'http://purl.obolibrary.org/obo/HP_0025405', 'lbl': 'Visual fixation instability', 'desc': 'label: Visual fixation instability\ndefinition : A deficit in the ability to fixate eye movements in order to stabilize images on the retina\nsynonyms :Instability of ocular fixation\n'}


{'id': 'HP_0025406', 'url': 'http://purl.obolibrary.org/obo/HP_0025406', 'lbl': 'Asthenia', 'desc': 'label: Asthenia\ndefinition : A state characterized by a feeling of weakness and loss of strength leading to a generalized weakness of the body.\nsynonyms :Lack of energy and strength; Weakness; Prostration\n'}


{'id': 'HP_0025407', 'url': 'http://purl.obolibrary.org/obo/HP_0025407', 'lbl': 'Rectourethral fistula', 'desc': 'label: Rectourethral fistula\ndefinition : An abnormal connection (fistula) between the rectum and the urethra.\nsynonyms :Urethrorectal fistula\n'}


{'id': 'HP_0025408', 'url': 'http://purl.obolibrary.org/obo/HP_0025408', 'lbl': 'Abnormal spleen morphology', 'desc': 'label: Abnormal spleen morphology\ndefinition : Any anomaly of the structure of the spleen.\nsynonyms :Splenic lesion\n'}


{'id': 'HP_0025409', 'url': 'http://purl.obolibrary.org/obo/HP_0025409', 'lbl': 'Abnormal spleen physiology', 'desc': 'label: Abnormal spleen physiology\ndefinition : Any anomaly of the function of the spleen.\nsynonyms :\n'}


{'id': 'HP_0025410', 'url': 'http://purl.obolibrary.org/obo/HP_0025410', 'lbl': 'Splenogonadal fusion', 'desc': 'label: Splenogonadal fusion\ndefinition : Joining of the spleen and a gonad during embryological development.\nsynonyms :\n'}


{'id': 'HP_0025413', 'url': 'http://purl.obolibrary.org/obo/HP_0025413', 'lbl': 'Fossa navicularis urethral stricture', 'desc': 'label: Fossa navicularis urethral stricture\ndefinition : A type of urethral stricture affecting the fossa navicularis, which is the spongy part of the male urethra located at the glans penis.\nsynonyms :\n'}


{'id': 'HP_0025414', 'url': 'http://purl.obolibrary.org/obo/HP_0025414', 'lbl': 'Pendulous urethral stricture', 'desc': 'label: Pendulous urethral stricture\ndefinition : A type of urethral stricture affecting the pendulous urethra, which is straight and fixed to the corpora cavernosa.\nsynonyms :\n'}


{'id': 'HP_0025415', 'url': 'http://purl.obolibrary.org/obo/HP_0025415', 'lbl': 'Bulbar urethral stricture', 'desc': 'label: Bulbar urethral stricture\ndefinition : A type of urethral stricture affecting the bulbar urethra, which is the part of the urethra that traverses the root of the penis.\nsynonyms :\n'}


{'id': 'HP_0025416', 'url': 'http://purl.obolibrary.org/obo/HP_0025416', 'lbl': 'Vaginal stricture', 'desc': 'label: Vaginal stricture\ndefinition : A narrowing of the vagina owing to scar formation.\nsynonyms :\n'}


{'id': 'HP_0025417', 'url': 'http://purl.obolibrary.org/obo/HP_0025417', 'lbl': 'Patulous urethra', 'desc': 'label: Patulous urethra\ndefinition : Urethra more open or expanded than normal.\nsynonyms :\n'}


{'id': 'HP_0025418', 'url': 'http://purl.obolibrary.org/obo/HP_0025418', 'lbl': 'Renal cortical necrosis', 'desc': 'label: Renal cortical necrosis\ndefinition : Patchy or diffuse ischemic destruction of all the elements of renal cortex resulting from significantly diminished renal arterial perfusion. Coagulative necrosis may be present, involving all tubular segments and glomeruli. Nuclei may be pale and pyknotic, or may no longer be apparent. Thrombi may be present in vessels at the edge of the infarct.\nsynonyms :Necrosis of the kidney cortex\n'}


{'id': 'HP_0025419', 'url': 'http://purl.obolibrary.org/obo/HP_0025419', 'lbl': 'Pulmonary pneumatocele', 'desc': 'label: Pulmonary pneumatocele\ndefinition : A pneumatocele is a thin walled, gas-filled space in the lung. It is most frequently caused by acute pneumonia, trauma, or aspiration of hydrocarbon fluid and is usually transient. The mechanism is believed to be a combination of parenchymal necrosis and check-valve airway obstruction. A pneumatocele appears as an approximately round, thin-walled airspace in the lung.\nsynonyms :Pulmonary pneumatocoele\n'}


{'id': 'HP_0025420', 'url': 'http://purl.obolibrary.org/obo/HP_0025420', 'lbl': 'Diffuse alveolar hemorrhage', 'desc': 'label: Diffuse alveolar hemorrhage\ndefinition : A type of of pulmonary hemorrhage that originates from the pulmonary microcirculation, including the alveolar capillaries, arterioles, and venules. It presents with hemoptysis, anemia, diffuse lung infiltration, and acute respiratory failure. The diagnosis is confirmed by the observation of the accumulation of red blood cells, fibrin, or hemosiderin-laden macrophage in the alveolar space on pathologic biopsy. Hemosiderin, a product of hemoglobin degradation, appears at least 48-72 hours after bleeding and is helpful in distinguishing diffuse alveolar hemorrhage from surgical trauma. Mild interstitial thickening, organizing pneumonia, or diffuse alveolar damage can also be seen.\nsynonyms :Diffuse alveolar haemorrhage\n'}


{'id': 'HP_0025421', 'url': 'http://purl.obolibrary.org/obo/HP_0025421', 'lbl': 'Pneumomediastinum', 'desc': 'label: Pneumomediastinum\ndefinition : The presence of free air in the mediastinum.\nsynonyms :\n'}


{'id': 'HP_0025422', 'url': 'http://purl.obolibrary.org/obo/HP_0025422', 'lbl': 'Pleural cyst', 'desc': 'label: Pleural cyst\ndefinition : A closed sac-like structure originating from the pleura that contains a liquid, gaseous, or semisolid substance.\nsynonyms :\n'}


{'id': 'HP_0025423', 'url': 'http://purl.obolibrary.org/obo/HP_0025423', 'lbl': 'Abnormal larynx morphology', 'desc': 'label: Abnormal larynx morphology\ndefinition : Any anomaly of the structure of the larynx.\nsynonyms :\n'}


{'id': 'HP_0025424', 'url': 'http://purl.obolibrary.org/obo/HP_0025424', 'lbl': 'Abnormal larynx physiology', 'desc': 'label: Abnormal larynx physiology\ndefinition : Any anomaly of the function of the larynx.\nsynonyms :\n'}


{'id': 'HP_0025425', 'url': 'http://purl.obolibrary.org/obo/HP_0025425', 'lbl': 'Laryngospasm', 'desc': 'label: Laryngospasm\ndefinition : A spasm (involuntary contraction) of the vocal cords that can make it difficult to speak or breathe.\nsynonyms :\n'}


{'id': 'HP_0025426', 'url': 'http://purl.obolibrary.org/obo/HP_0025426', 'lbl': 'Abnormal bronchus morphology', 'desc': 'label: Abnormal bronchus morphology\ndefinition : Any structural anomaly of the bronchi, i.e., of the airways leading from the trachea to the lungs.\nsynonyms :Abnormality of the bronchi\n'}


{'id': 'HP_0025427', 'url': 'http://purl.obolibrary.org/obo/HP_0025427', 'lbl': 'Abnormal bronchus physiology', 'desc': 'label: Abnormal bronchus physiology\ndefinition : Any anomaly of the function of the bronchi.\nsynonyms :\n'}


{'id': 'HP_0025428', 'url': 'http://purl.obolibrary.org/obo/HP_0025428', 'lbl': 'Bronchospasm', 'desc': 'label: Bronchospasm\ndefinition : A spasm (sudden, involuntary constriction) of the bronchioles.\nsynonyms :\n'}


{'id': 'HP_0025429', 'url': 'http://purl.obolibrary.org/obo/HP_0025429', 'lbl': 'Abnormal cry', 'desc': "label: Abnormal cry\ndefinition : Any anomaly of the vocalizing of an infant's crying, i.e.,the typically loud voice production that is accompanied by tears and agitation.\nsynonyms :\n"}


{'id': 'HP_0025430', 'url': 'http://purl.obolibrary.org/obo/HP_0025430', 'lbl': 'High-pitched cry', 'desc': 'label: High-pitched cry\ndefinition : A type of crying in an abnormally high-pitched voice.\nsynonyms :\n'}


{'id': 'HP_0025431', 'url': 'http://purl.obolibrary.org/obo/HP_0025431', 'lbl': 'Staccato cry', 'desc': 'label: Staccato cry\ndefinition : A type of cry that is abnormal because it is consists of unusually shortened and detached vocalizations.\nsynonyms :\n'}


{'id': 'HP_0025432', 'url': 'http://purl.obolibrary.org/obo/HP_0025432', 'lbl': 'Acanthoma', 'desc': 'label: Acanthoma\ndefinition : A benign epithelial skin tumor manifesting as a slightly elevated circular plaque or nodule with a red, pink or brown color and a diameter up to 22 mm.\nsynonyms :\n'}


{'id': 'HP_0025433', 'url': 'http://purl.obolibrary.org/obo/HP_0025433', 'lbl': 'Decreased lecithin cholesterol acyl transferase level', 'desc': 'label: Decreased lecithin cholesterol acyl transferase level\ndefinition : Reduced level of the enzyme lecithin cholesterol acyl transferase.\nsynonyms :\n'}


{'id': 'HP_0025434', 'url': 'http://purl.obolibrary.org/obo/HP_0025434', 'lbl': 'Reduced hemolytic complement activity', 'desc': 'label: Reduced hemolytic complement activity\ndefinition : A diminished activity of the classical complement pathway as measured by the assay for 50% haemolytic complement (CH50) activity of serum.\nsynonyms :Reduced CH50\n'}


{'id': 'HP_0025435', 'url': 'http://purl.obolibrary.org/obo/HP_0025435', 'lbl': 'Increased circulating lactate dehydrogenase concentration', 'desc': 'label: Increased circulating lactate dehydrogenase concentration\ndefinition : An elevated level of the enzyme lactate dehydrogenase in the blood circulation.\nsynonyms :Increased lactate dehydrogenase level\n'}


{'id': 'HP_0025436', 'url': 'http://purl.obolibrary.org/obo/HP_0025436', 'lbl': 'Elevated serum 11-deoxycortisol', 'desc': 'label: Elevated serum 11-deoxycortisol\ndefinition : Increased concentration of 11-deoxycortisol in the circulation. 11-deoxycorticosterone, which is also known as simply deoxycorticosterone and 21-hydroxyprogesterone, is a steroid hormore that is produces in the adrenals and is a precursor to aldosterone.\nsynonyms :Elevated serum 21-hydroxyprogesterone; Elevated serum deoxycorticosterone\n'}


{'id': 'HP_0025437', 'url': 'http://purl.obolibrary.org/obo/HP_0025437', 'lbl': 'Macrocephalic sperm head', 'desc': 'label: Macrocephalic sperm head\ndefinition : Increased size of the head of sperm.\nsynonyms :\n'}


{'id': 'HP_0025439', 'url': 'http://purl.obolibrary.org/obo/HP_0025439', 'lbl': 'Pharyngitis', 'desc': 'label: Pharyngitis\ndefinition : Inflammation (due to infection or irritation) of the pharynx.\nsynonyms :\n'}


{'id': 'HP_0025440', 'url': 'http://purl.obolibrary.org/obo/HP_0025440', 'lbl': 'Warm reactive autoantibody positivity', 'desc': 'label: Warm reactive autoantibody positivity\ndefinition : Warm reactive autoantibodies are RBC-directed immune responses that are maximally reactive at 37 degrees C.\nsynonyms :\n'}


{'id': 'HP_0025441', 'url': 'http://purl.obolibrary.org/obo/HP_0025441', 'lbl': 'Achilles tendon calcification', 'desc': 'label: Achilles tendon calcification\ndefinition : Ectopic deposition of calcium salts in the Achilles tendon.\nsynonyms :Calcification of the Achilles tendon\n'}


{'id': 'HP_0025443', 'url': 'http://purl.obolibrary.org/obo/HP_0025443', 'lbl': 'Abnormal cardiac atrial physiology', 'desc': 'label: Abnormal cardiac atrial physiology\ndefinition : An abnormality of the function of the cardiac atria.\nsynonyms :\n'}


{'id': 'HP_0025444', 'url': 'http://purl.obolibrary.org/obo/HP_0025444', 'lbl': 'Reduced amygdala volume', 'desc': 'label: Reduced amygdala volume\ndefinition : A decrease in the volume (size) of the amygdyla.\nsynonyms :Decrease in amygdala volume\n'}


{'id': 'HP_0025445', 'url': 'http://purl.obolibrary.org/obo/HP_0025445', 'lbl': 'Morphological abnormality of the papillary muscles', 'desc': 'label: Morphological abnormality of the papillary muscles\ndefinition : Any structural anomaly of the papillary muscles of the left ventricle.\nsynonyms :\n'}


{'id': 'HP_0025446', 'url': 'http://purl.obolibrary.org/obo/HP_0025446', 'lbl': 'Anomalous insertion of papillary muscle directly into anterior mitral leaflet', 'desc': 'label: Anomalous insertion of papillary muscle directly into anterior mitral leaflet\ndefinition : A congenital malformation in which one or both of the papillary muscles (posteromedial or anterolateral) insert directly (that is, without interpositioned chordae tendineae) into the anterior mitral leaflet.\nsynonyms :\n'}


{'id': 'HP_0025447', 'url': 'http://purl.obolibrary.org/obo/HP_0025447', 'lbl': 'Displacement of the papillary muscles', 'desc': 'label: Displacement of the papillary muscles\ndefinition : Abnormal location of the insertion of a papillary muscle into the left ventricular wall.\nsynonyms :\n'}


{'id': 'HP_0025448', 'url': 'http://purl.obolibrary.org/obo/HP_0025448', 'lbl': 'Anterior displacement of the papillary muscles', 'desc': 'label: Anterior displacement of the papillary muscles\ndefinition : Abnormally anterior location of the papillary muscles of the left ventricle.\nsynonyms :Anteriorly displaced papillary muscles\n'}


{'id': 'HP_0025449', 'url': 'http://purl.obolibrary.org/obo/HP_0025449', 'lbl': 'Apically displaced anterolateral papillary muscle', 'desc': 'label: Apically displaced anterolateral papillary muscle\ndefinition : Abnormal location of the insertion of the anterolateral papillary muscle near to the apex of the left ventricle. This feature may be appreciated by noting that this muscle is usually not seen in the apical level of the parasternal short-axis echocardiographic view,\nsynonyms :Apically displaced papillary muscles\n'}


{'id': 'HP_0025451', 'url': 'http://purl.obolibrary.org/obo/HP_0025451', 'lbl': 'Testicular adrenal rest tumor', 'desc': 'label: Testicular adrenal rest tumor\ndefinition : Testicular adrenal rest tumor (TART) is a abenign tumor of the testis. TART generally occurs multiply and bilaterally within the rete testis. Histologically, TART resemble adrenocortical tissue, which led to the name. The tumous are not encapsulated and consist of sheets or confluent cords of large polygonal cells with abundant eosinophilic cytoplasm.\nsynonyms :Testicular adrenal rest tumour\n'}


{'id': 'HP_0025452', 'url': 'http://purl.obolibrary.org/obo/HP_0025452', 'lbl': 'Pyoderma gangrenosum', 'desc': "label: Pyoderma gangrenosum\ndefinition : A deep skin ulcer with a well defined border, which is usually violet or blue. The ulcer edge is often undermined (worn and damaged) and the surrounding skin is erythematous and indurated. The ulcer often starts as a small papule or collection of papules, which break down to form small ulcers with a so called cat's paw appearance. These coalesce and the central area then undergoes necrosis to form a single ulcer.\nsynonyms :\n"}


{'id': 'HP_0025453', 'url': 'http://purl.obolibrary.org/obo/HP_0025453', 'lbl': 'Delayed adrenarche', 'desc': 'label: Delayed adrenarche\ndefinition : Occurence of adrenarche at a later than normal age. Adrenarche normally occurs between six and eight years of age with increased adrenal androgen secretion; its exact biologic role is not well understood. It is accompanied by changes in pilosebaceous units, a transient growth spurt and the appearance of axillary and pubic hair in some children, but no sexual development.\nsynonyms :\n'}


{'id': 'HP_0025454', 'url': 'http://purl.obolibrary.org/obo/HP_0025454', 'lbl': 'Abnormal CSF metabolite concentration', 'desc': 'label: Abnormal CSF metabolite concentration\ndefinition : Any deviation from the normal range of concentration of a metabolite in the cerebrospinal fluid.\nsynonyms :Abnormal CSF metabolite level; Abnormal cerebrospinal fluid metabolite concentration\n'}


{'id': 'HP_0025455', 'url': 'http://purl.obolibrary.org/obo/HP_0025455', 'lbl': 'Decreased CSF 5-hydroxyindolacetic acid concentration', 'desc': 'label: Decreased CSF 5-hydroxyindolacetic acid concentration\ndefinition : 5-HIAA (5-hydroxyindolacetic acid) concentration in the cerebrospinal fluid (CSF) is below the lower limit of normal.\nsynonyms :Decreased CSF 5-HIAA; Low CSF 5-HIAA; Low CSF 5-hydroxyindolacetic acid\n'}


{'id': 'HP_0025456', 'url': 'http://purl.obolibrary.org/obo/HP_0025456', 'lbl': 'Abnormal CSF protein concentration', 'desc': 'label: Abnormal CSF protein concentration\ndefinition : Any deviation from the normal range of a protein concentration in the cerebrospinal fluid.\nsynonyms :Abnormal CSF protein level\n'}


{'id': 'HP_0025457', 'url': 'http://purl.obolibrary.org/obo/HP_0025457', 'lbl': 'Decreased CSF protein concentration', 'desc': 'label: Decreased CSF protein concentration\ndefinition : CSF total protein level is below the lower limit of normal.\nsynonyms :Decreased CSF protein; Decreased cerebrospinal fluid total protein; Hypoproteinorrhachia; Low CSF total protein\n'}


{'id': 'HP_0025458', 'url': 'http://purl.obolibrary.org/obo/HP_0025458', 'lbl': 'Decreased CSF albumin concentration', 'desc': 'label: Decreased CSF albumin concentration\ndefinition : CSF albumin level is below the lower limit of normal.\nsynonyms :Low CSF albumin\n'}


{'id': 'HP_0025459', 'url': 'http://purl.obolibrary.org/obo/HP_0025459', 'lbl': 'Increased CSF/serum albumin ratio', 'desc': 'label: Increased CSF/serum albumin ratio\ndefinition : An increase above normal limits of the ratio of the cerebrospinal fluid (CSF) albumin concentration to serum albumin concentration.\nsynonyms :\n'}


{'id': 'HP_0025460', 'url': 'http://purl.obolibrary.org/obo/HP_0025460', 'lbl': 'High myoinositol in brain by MRS', 'desc': 'label: High myoinositol in brain by MRS\ndefinition : An elevated level of myoinositol in the brain identified by magnetic resonance spectroscopy (MRS).\nsynonyms :High myo-inositol in brain by MRS\n'}


{'id': 'HP_0025461', 'url': 'http://purl.obolibrary.org/obo/HP_0025461', 'lbl': 'Abnormal cell morphology', 'desc': 'label: Abnormal cell morphology\ndefinition : Any anomaly of cell structure.\nsynonyms :\n'}


{'id': 'HP_0025462', 'url': 'http://purl.obolibrary.org/obo/HP_0025462', 'lbl': 'obsolete Abnormal cellular physiology', 'desc': 'label: obsolete Abnormal cellular physiology\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0025463', 'url': 'http://purl.obolibrary.org/obo/HP_0025463', 'lbl': 'Abnormality of redox activity', 'desc': 'label: Abnormality of redox activity\ndefinition : An abnormality of the processes that maintain the redox environment of a cell or compartment within a cell, that is, the balance between reduction and oxidation chemical reactions.\nsynonyms :\n'}


{'id': 'HP_0025464', 'url': 'http://purl.obolibrary.org/obo/HP_0025464', 'lbl': 'Increased reactive oxygen species production', 'desc': 'label: Increased reactive oxygen species production\ndefinition : An accumulation of free radical groups in the body inadequately neutralized by antioxidants, which creates a potentially unstable and damaging cellular environment linked to tissue damage.\nsynonyms :Increased ROS production; Oxidative stress\n'}


{'id': 'HP_0025465', 'url': 'http://purl.obolibrary.org/obo/HP_0025465', 'lbl': 'Abnormal circulating beta globulin level', 'desc': 'label: Abnormal circulating beta globulin level\ndefinition : A deviation from the normal concentration of beta globulin. The beta globulins are a group of globular (globe-shaped) proteins in blood.\nsynonyms :\n'}


{'id': 'HP_0025466', 'url': 'http://purl.obolibrary.org/obo/HP_0025466', 'lbl': 'Beta 2-microglobulinuria', 'desc': 'label: Beta 2-microglobulinuria\ndefinition : Increased level of beta 2-microglobulins in the urine.\nsynonyms :\n'}


{'id': 'HP_0025469', 'url': 'http://purl.obolibrary.org/obo/HP_0025469', 'lbl': 'Anagen effluvium', 'desc': 'label: Anagen effluvium\ndefinition : An abnormal loss of anagen (growth phase) hairs.\nsynonyms :\n'}


{'id': 'HP_0025470', 'url': 'http://purl.obolibrary.org/obo/HP_0025470', 'lbl': 'Telogen effluvium', 'desc': 'label: Telogen effluvium\ndefinition : A type of hair loss characterized by an abnormal increase in dormant, telogen stage hair follicles.\nsynonyms :\n'}


{'id': 'HP_0025471', 'url': 'http://purl.obolibrary.org/obo/HP_0025471', 'lbl': 'Congenital panfollicular nevus', 'desc': 'label: Congenital panfollicular nevus\ndefinition : A hamartomatous proliferation containing malformed hair follicles in various stages of development. Panfolliculomas are well-circumscribed lesions demonstrating all stages of follicular differentiation.\nsynonyms :\n'}


{'id': 'HP_0025472', 'url': 'http://purl.obolibrary.org/obo/HP_0025472', 'lbl': 'Recurrent plantar mycosis', 'desc': 'label: Recurrent plantar mycosis\ndefinition : A history of repeated fungal infections located on the sole of the foot, usually manifested by scaling, maceration, and itching.\nsynonyms :\n'}


{'id': 'HP_0025473', 'url': 'http://purl.obolibrary.org/obo/HP_0025473', 'lbl': 'Hyperpigmented papule', 'desc': 'label: Hyperpigmented papule\ndefinition : A papule (circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point) that exhibits increased pigmentation (is darker) compared to the surrounding skin.\nsynonyms :\n'}


{'id': 'HP_0025474', 'url': 'http://purl.obolibrary.org/obo/HP_0025474', 'lbl': 'Erythematous plaque', 'desc': 'label: Erythematous plaque\ndefinition : A plaque (a solid, raised, plateau-like (flat-topped) lesion greater than 1 cm in diameter) with a red or reddish color often associated with inflammation or irritation.\nsynonyms :Violaceous plaque\n'}


{'id': 'HP_0025475', 'url': 'http://purl.obolibrary.org/obo/HP_0025475', 'lbl': 'Erythematous macule', 'desc': 'label: Erythematous macule\ndefinition : A macule (flat, distinct, discolored area of skin less than 1 cm wide that does not involve any change in the thickness or texture of the skin) with a red or reddish color often associated with inflammation or irritation.\nsynonyms :\n'}


{'id': 'HP_0025476', 'url': 'http://purl.obolibrary.org/obo/HP_0025476', 'lbl': 'Testicular lipomatosis', 'desc': 'label: Testicular lipomatosis\ndefinition : Multiple foci of adipocytes within the testicular interstitium, usually presenting as multiple bilateral ill-defined hyperechoic intratesticular lesions of different sizes but generally with maximum diameter of 4 mm.\nsynonyms :\n'}


{'id': 'HP_0025477', 'url': 'http://purl.obolibrary.org/obo/HP_0025477', 'lbl': 'Periarticular calcification', 'desc': 'label: Periarticular calcification\ndefinition : Calcified deposits in soft tissue structures outside a joint.\nsynonyms :\n'}


{'id': 'HP_0025478', 'url': 'http://purl.obolibrary.org/obo/HP_0025478', 'lbl': 'Atrial standstill', 'desc': 'label: Atrial standstill\ndefinition : Atrial standstill or silent atrium is a rare condition presenting with the absence of electrical and mechanical activity in the atria. It presents with the absence of P waves, bradycardia, and wide QRS complex in the electrocardiogram.\nsynonyms :Silent atrium\n'}


{'id': 'HP_0025479', 'url': 'http://purl.obolibrary.org/obo/HP_0025479', 'lbl': 'Self-neglect', 'desc': "label: Self-neglect\ndefinition : Neglecting one's own needs and well-being.\nsynonyms :\n"}


{'id': 'HP_0025480', 'url': 'http://purl.obolibrary.org/obo/HP_0025480', 'lbl': 'Lipomyelomeningocele', 'desc': 'label: Lipomyelomeningocele\ndefinition : A type of spinal dysraphism presenting as a subcutaneous fatty mass, that is, a spinal defect associated with lipomatous tissue, and covered by skin. The most usual location for lipomyelomeningocele is at the gluteal cleft.\nsynonyms :\n'}


{'id': 'HP_0025481', 'url': 'http://purl.obolibrary.org/obo/HP_0025481', 'lbl': 'Cervical hemivertebrae', 'desc': 'label: Cervical hemivertebrae\ndefinition : Absence of one half of the vertebral body in the cervical spine.\nsynonyms :\n'}


{'id': 'HP_0025482', 'url': 'http://purl.obolibrary.org/obo/HP_0025482', 'lbl': 'Positive perchlorate discharge test', 'desc': 'label: Positive perchlorate discharge test\ndefinition : An abnormal result of the perchlorate discharge test. In this test, first radioactive iodine is administered, sufficient time is allowed to pass so that the radioactive iodine is captured by the thyroid,and then, perchlorate is administered orally. The perchlorate displaces non-organified iodide from the thyroid. The perchlorate discharge test is considered positive (abnormal) if there is an abnormally rapid loss of radioactive iodine from the thyroid.\nsynonyms :\n'}


{'id': 'HP_0025483', 'url': 'http://purl.obolibrary.org/obo/HP_0025483', 'lbl': 'Abnormal circulating thyroglobulin level', 'desc': 'label: Abnormal circulating thyroglobulin level\ndefinition : A deviation from the normal concentration of thyroglobulin, a protein produced in the thyroid gland that acts as a precursor to thyrroid hormones.\nsynonyms :\n'}


{'id': 'HP_0025484', 'url': 'http://purl.obolibrary.org/obo/HP_0025484', 'lbl': 'Increased circulating thyroglobulin level', 'desc': 'label: Increased circulating thyroglobulin level\ndefinition : An abnormal elevation of the concentration of thyroglobulin, a protein produced in the thyroid gland that acts as a precursor to thyrroid hormones.\nsynonyms :\n'}


{'id': 'HP_0025485', 'url': 'http://purl.obolibrary.org/obo/HP_0025485', 'lbl': 'Vaginal adenosis', 'desc': 'label: Vaginal adenosis\ndefinition : Vaginal adenosis is defined by the presence of metaplastic cervical or endometrial epithelium within the vaginal wall, thought to be derived from persistent Müllerian (synonymous with paramesonephric) epithelium islets in postembryonic life.\nsynonyms :\n'}


{'id': 'HP_0025486', 'url': 'http://purl.obolibrary.org/obo/HP_0025486', 'lbl': 'Fused labia majora', 'desc': 'label: Fused labia majora\ndefinition : The outer labia are sealed together.\nsynonyms :\n'}


{'id': 'HP_0025487', 'url': 'http://purl.obolibrary.org/obo/HP_0025487', 'lbl': 'Abnormality of bladder morphology', 'desc': 'label: Abnormality of bladder morphology\ndefinition : Any structural anomaly of the bladder.\nsynonyms :\n'}