{'id': 'HP_0012036', 'url': 'http://purl.obolibrary.org/obo/HP_0012036', 'lbl': 'Sternocleidomastoid amyotrophy', 'desc': 'label: Sternocleidomastoid amyotrophy\ndefinition : Wasting of the sternocleidomastoid muscle, the muscle in the anterior part of the neck that acts to flex and rotate the head.\nsynonyms :\n'}


{'id': 'HP_0012037', 'url': 'http://purl.obolibrary.org/obo/HP_0012037', 'lbl': 'Pectoralis amyotrophy', 'desc': 'label: Pectoralis amyotrophy\ndefinition : Wasting of the pectoral muscles, i.e., of the pectoralis major and pectoralis minor.\nsynonyms :Wasting of pec muscles\n'}


{'id': 'HP_0012038', 'url': 'http://purl.obolibrary.org/obo/HP_0012038', 'lbl': 'Corneal guttata', 'desc': "label: Corneal guttata\ndefinition : Corneal guttata are droplet-like accumulations of non-banded collagen on the posterior surface of Descemet's membrane. The presence of focal thickenings of Descemet's membrane histologically named guttae. Cornea guttata can be easily diagnosed in vivo and ex vivo by means of specular microscopy as it gives dark areas where no endothelial cells are visible.\nsynonyms :Corneal endothelial guttata; Corneal guttae\n"}


{'id': 'HP_0012039', 'url': 'http://purl.obolibrary.org/obo/HP_0012039', 'lbl': 'Descemet Membrane Folds', 'desc': 'label: Descemet Membrane Folds\ndefinition : Presence of folds in the Descemet membrane, which is the basement membrane of the endothelial (inner) cell layer of the cornea. Descemet membrane folds are generally a manifestation of inflammation or edema of the cornea.\nsynonyms :\n'}


{'id': 'HP_0012040', 'url': 'http://purl.obolibrary.org/obo/HP_0012040', 'lbl': 'Corneal stromal edema', 'desc': 'label: Corneal stromal edema\ndefinition : Abnormal accumulation of fluid and swelling of the stroma of cornea.\nsynonyms :Corneal stromal oedema\n'}


{'id': 'HP_0012041', 'url': 'http://purl.obolibrary.org/obo/HP_0012041', 'lbl': 'Decreased fertility in males', 'desc': 'label: Decreased fertility in males\ndefinition : \nsynonyms :Decreased fertility in males\n'}


{'id': 'HP_0012042', 'url': 'http://purl.obolibrary.org/obo/HP_0012042', 'lbl': 'Aspirin-induced asthma', 'desc': 'label: Aspirin-induced asthma\ndefinition : A type of asthma in which aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygen-ase 1 (COX-1) exacerbate bronchoconstriction.\nsynonyms :Aspirin-induced asthma\n'}


{'id': 'HP_0012043', 'url': 'http://purl.obolibrary.org/obo/HP_0012043', 'lbl': 'Pendular nystagmus', 'desc': 'label: Pendular nystagmus\ndefinition : Rhythmic, involuntary sinusoidal oscillations of one or both eyes. The waveform of pendular nystagmus may occur in any direction.\nsynonyms :Nystagmus, continuous pendular; Nystagmus, pendular\n'}


{'id': 'HP_0012044', 'url': 'http://purl.obolibrary.org/obo/HP_0012044', 'lbl': 'Seesaw nystagmus', 'desc': 'label: Seesaw nystagmus\ndefinition : Seesaw nystagmus is a type of pendular nystagmus where a half cycle consists of the elevation and intorsion of one eye, concurrently with the depression and extortion of the fellow eye. In the other half cycle, there is an inversion of the ocular movements.\nsynonyms :\n'}


{'id': 'HP_0012045', 'url': 'http://purl.obolibrary.org/obo/HP_0012045', 'lbl': 'Retinal flecks', 'desc': 'label: Retinal flecks\ndefinition : Presence of multiple yellowish-white lesions of various size and configuration on the retina not related to vascular lesions.\nsynonyms :\n'}


{'id': 'HP_0012046', 'url': 'http://purl.obolibrary.org/obo/HP_0012046', 'lbl': 'Areflexia of upper limbs', 'desc': 'label: Areflexia of upper limbs\ndefinition : Inability to elicit tendon reflexes in the upper limbs.\nsynonyms :\n'}


{'id': 'HP_0012047', 'url': 'http://purl.obolibrary.org/obo/HP_0012047', 'lbl': 'Hemeralopia', 'desc': 'label: Hemeralopia\ndefinition : A visual defect characterized by the inability to see as clearly in bright light as in dim light. The word hemeralopia literally means day blindness.\nsynonyms :Day blindness\n'}


{'id': 'HP_0012048', 'url': 'http://purl.obolibrary.org/obo/HP_0012048', 'lbl': 'Oromandibular dystonia', 'desc': 'label: Oromandibular dystonia\ndefinition : A kind of focal dystonia characterized by forceful contractions of the face, jaw, and/or tongue causing difficulty in opening and closing the mouth and often affecting chewing and speech.\nsynonyms :Cranial dystonia\n'}


{'id': 'HP_0012049', 'url': 'http://purl.obolibrary.org/obo/HP_0012049', 'lbl': 'Laryngeal dystonia', 'desc': 'label: Laryngeal dystonia\ndefinition : A form of focal dystonia that affects the vocal cords, associated with involuntary contractions of the vocal cords causing interruptions of speech and affecting the voice quality and often leading to patterned, repeated breaks in speech.\nsynonyms :Spasmodic dysphonia\n'}


{'id': 'HP_0012050', 'url': 'http://purl.obolibrary.org/obo/HP_0012050', 'lbl': 'Anasarca', 'desc': 'label: Anasarca\ndefinition : An extreme form of generalized edema with widespread and massive edema due to effusion of fluid into the extracellular space.\nsynonyms :Extreme generalised oedema; Extreme generalized edema\n'}


{'id': 'HP_0012051', 'url': 'http://purl.obolibrary.org/obo/HP_0012051', 'lbl': 'Reactive hypoglycemia', 'desc': 'label: Reactive hypoglycemia\ndefinition : Hypoglycermia following a meal (or more generally, after intake of glucose).\nsynonyms :Low blood sugar after a meal; Postprandial hypoglycemia\n'}


{'id': 'HP_0012052', 'url': 'http://purl.obolibrary.org/obo/HP_0012052', 'lbl': 'Low serum calcitriol', 'desc': 'label: Low serum calcitriol\ndefinition : A reduced concentration of calcitriol in the blood. Calcitriol is also known as 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3.\nsynonyms :Low serum 1,25-dihydroxycholecalciferol; Low serum 1,25-dihydroxyvitamin D3\n'}


{'id': 'HP_0012053', 'url': 'http://purl.obolibrary.org/obo/HP_0012053', 'lbl': 'Decreased circulating calcifediol concentration', 'desc': 'label: Decreased circulating calcifediol concentration\ndefinition : A reduced concentration of calcifediol in the blood. Calcifediol is also known as calcidiol, 25-hydroxycholecalciferol and 25-Hydroxyvitamin D3.\nsynonyms :Decreased 25-hydroxyvitamin D3; Low serum 25-hydroxycholecalciferol; Low serum calcidiol; Low serum calcifediol\n'}


{'id': 'HP_0012054', 'url': 'http://purl.obolibrary.org/obo/HP_0012054', 'lbl': 'Choroidal melanoma', 'desc': 'label: Choroidal melanoma\ndefinition : Malignant tumor of melanocytes of the choroid. The classic appearance of choroidal melanoma is a pigmented dome-shaped or collar button-shaped tumor with an associated exudative retinal detachment. Choroidal melanoma is usually pigmented, but can be variably pigmented and even amelanotic (non-pigmented).\nsynonyms :\n'}


{'id': 'HP_0012055', 'url': 'http://purl.obolibrary.org/obo/HP_0012055', 'lbl': 'Ciliary body melanoma', 'desc': 'label: Ciliary body melanoma\ndefinition : Malignant tumor of melanocytes of the ciliary body.\nsynonyms :\n'}


{'id': 'HP_0012056', 'url': 'http://purl.obolibrary.org/obo/HP_0012056', 'lbl': 'Cutaneous melanoma', 'desc': 'label: Cutaneous melanoma\ndefinition : The presence of a melanoma of the skin.\nsynonyms :\n'}


{'id': 'HP_0012057', 'url': 'http://purl.obolibrary.org/obo/HP_0012057', 'lbl': 'Superficial spreading melanoma', 'desc': 'label: Superficial spreading melanoma\ndefinition : A type of melanoma that is flat and irregular in shape and color, with different shades of black and brown.\nsynonyms :\n'}


{'id': 'HP_0012058', 'url': 'http://purl.obolibrary.org/obo/HP_0012058', 'lbl': 'Nodular melanoma', 'desc': 'label: Nodular melanoma\ndefinition : A type of melanoma that starts as a raised area that is usually dark blackish-blue or bluish-red but may not have any color.\nsynonyms :\n'}


{'id': 'HP_0012059', 'url': 'http://purl.obolibrary.org/obo/HP_0012059', 'lbl': 'Lentigo maligna melanoma', 'desc': 'label: Lentigo maligna melanoma\ndefinition : A subtype of melanoma in situ that typically develops on sun-damaged skin. The lesion is typically a large, irregularly pigmented macule that has developed from an ordinary lentigo (a small pigmented spot on the skin with a clearly-defined edge). Change to a malignant lentigo typically takes place over 20 years or more, and many patients accept the change as a consequence of aging.\nsynonyms :\n'}


{'id': 'HP_0012060', 'url': 'http://purl.obolibrary.org/obo/HP_0012060', 'lbl': 'Acral lentiginous melanoma', 'desc': 'label: Acral lentiginous melanoma\ndefinition : A type of cutaneous melanoma localized to the palm, sole, or beneath the nail (subungual melanoma). Acral lentiginous melanoma starts as a slowly-enlarging flat patch of discoloured skin and usually displays a size above 6 mm and often several centimetres or more in diameter upon diagnosis and variable pigmentation with a mixutre of colors including brown, and blue-grey, black and red. The surface of the lesion is initially smooth but later in the course may become thicker and irregular, and may ulcerate or bleed.\nsynonyms :\n'}


{'id': 'HP_0012061', 'url': 'http://purl.obolibrary.org/obo/HP_0012061', 'lbl': 'Urinary excretion of sialylated oligosaccharides', 'desc': 'label: Urinary excretion of sialylated oligosaccharides\ndefinition : Excretion of oligosaccharides conjugated to sialic acid in the urine.\nsynonyms :Increased urinary sialyloligosaccharides\n'}


{'id': 'HP_0012062', 'url': 'http://purl.obolibrary.org/obo/HP_0012062', 'lbl': 'Bone cyst', 'desc': 'label: Bone cyst\ndefinition : A fluid filled cavity that develops with a bone.\nsynonyms :Bone cyst; Bone cysts\n'}


{'id': 'HP_0012063', 'url': 'http://purl.obolibrary.org/obo/HP_0012063', 'lbl': 'Aneurysmal bone cyst', 'desc': 'label: Aneurysmal bone cyst\ndefinition : Radiographic features include a dilated, radiolucent lesion typically located eccentrically within the metaphyseal portion of the bone, with fluid levels visible on magnetic resonance imaging.\nsynonyms :\n'}


{'id': 'HP_0012064', 'url': 'http://purl.obolibrary.org/obo/HP_0012064', 'lbl': 'Unicameral bone cyst', 'desc': 'label: Unicameral bone cyst\ndefinition : A benign fluid filled simple cyst of bone filled with serous fluid.\nsynonyms :\n'}


{'id': 'HP_0012065', 'url': 'http://purl.obolibrary.org/obo/HP_0012065', 'lbl': 'Multiple bony cystic lesions', 'desc': 'label: Multiple bony cystic lesions\ndefinition : Presence of multiple cystic changes in multiple areas or multiple bones.\nsynonyms :Multiple bony cystic lesions\n'}


{'id': 'HP_0012066', 'url': 'http://purl.obolibrary.org/obo/HP_0012066', 'lbl': 'Increased urinary disaccharide excretion', 'desc': 'label: Increased urinary disaccharide excretion\ndefinition : Increased concentration of disaccharide in the urine.\nsynonyms :\n'}


{'id': 'HP_0012067', 'url': 'http://purl.obolibrary.org/obo/HP_0012067', 'lbl': 'Glycopeptiduria', 'desc': 'label: Glycopeptiduria\ndefinition : Increased excretion of glycopeptides in the urine. Glycopeptides are peptides with carbohydrate moieties covalently attached to the side chains of the amino acid residues.\nsynonyms :High urine glycopeptide levels\n'}


{'id': 'HP_0012068', 'url': 'http://purl.obolibrary.org/obo/HP_0012068', 'lbl': 'Aspartylglucosaminuria', 'desc': 'label: Aspartylglucosaminuria\ndefinition : Excretion of excess amounts of aspartylglucosamine in the urine.\nsynonyms :High urine aspartylglucosamine levels\n'}


{'id': 'HP_0012069', 'url': 'http://purl.obolibrary.org/obo/HP_0012069', 'lbl': 'Keratan sulfate excretion in urine', 'desc': 'label: Keratan sulfate excretion in urine\ndefinition : An increased concentration of keratan sulfate in the urine.\nsynonyms :Keratan sulphate excretion in urine\n'}


{'id': 'HP_0012070', 'url': 'http://purl.obolibrary.org/obo/HP_0012070', 'lbl': 'Chondroitin sulfate excretion in urine', 'desc': 'label: Chondroitin sulfate excretion in urine\ndefinition : An increased concentration of chondroitin sulfate (CHEBI:37397) in the urine.\nsynonyms :Chondroitin sulphate excretion in urine\n'}


{'id': 'HP_0012071', 'url': 'http://purl.obolibrary.org/obo/HP_0012071', 'lbl': 'Abnormal circulating acetylcarnitine concentration', 'desc': 'label: Abnormal circulating acetylcarnitine concentration\ndefinition : Any deviation from the normal concentration in the blood circulation of acylcarnitine, which is produced by reversible esterification of the 3-hydroxyl group of carnitine.\nsynonyms :Abnormal circulating esterified carnitine concentration; Abnormal acetylcarnitine profile\n'}


{'id': 'HP_0012072', 'url': 'http://purl.obolibrary.org/obo/HP_0012072', 'lbl': 'Aciduria', 'desc': 'label: Aciduria\ndefinition : Excretion of urine with an acid pH, i.e., having an increased hydrogen ion concentration.\nsynonyms :Acidic urine\n'}


{'id': 'HP_0012073', 'url': 'http://purl.obolibrary.org/obo/HP_0012073', 'lbl': 'Abnormal urinary acylglycine profile', 'desc': 'label: Abnormal urinary acylglycine profile\ndefinition : An abnormal distribution of N-acylglycines in the urine. There are numerous different N-acylglycines, and this term refers to pathological alterations in their level or distribution.\nsynonyms :\n'}


{'id': 'HP_0012074', 'url': 'http://purl.obolibrary.org/obo/HP_0012074', 'lbl': 'Tonic pupil', 'desc': "label: Tonic pupil\ndefinition : An abnormality of the pupillary light reaction characterized by a marked slowing of the light reaction of usually just one pupil. The pupil tends to be relatively dilated, and there is reduced accommodation.\nsynonyms :Adie pupil; Adie's tonic pupil\n"}


{'id': 'HP_0012075', 'url': 'http://purl.obolibrary.org/obo/HP_0012075', 'lbl': 'Personality disorder', 'desc': 'label: Personality disorder\ndefinition : An abnormality of mental functioning affecting the personality and behavioural tendencies of an individual and characterized by a rigid and unhealthy pattern of thinking and behavior. The definition of a personal disorder implies that the abnormality is not the result of damage or insult to the brain or from another psychiatric disorder.\nsynonyms :\n'}


{'id': 'HP_0012076', 'url': 'http://purl.obolibrary.org/obo/HP_0012076', 'lbl': 'Borderline personality disorder', 'desc': 'label: Borderline personality disorder\ndefinition : A personality disorder characterized by impulsive behavior and unpredictable and capricious mood. Affected individuals show a liability to outbursts of emotion and an incapacity to control the behavioural explosions.\nsynonyms :BPD\n'}


{'id': 'HP_0012077', 'url': 'http://purl.obolibrary.org/obo/HP_0012077', 'lbl': 'Histrionic personality disorder', 'desc': 'label: Histrionic personality disorder\ndefinition : A personality disorder characterized by shallow and labile affectivity, self-dramatization, theatricality, exaggerated expression of emotions, suggestibility, egocentricity, self-indulgence, lack of consideration for others, easily hurt feelings, and continuous seeking for appreciation, excitement and attention.\nsynonyms :\n'}


{'id': 'HP_0012078', 'url': 'http://purl.obolibrary.org/obo/HP_0012078', 'lbl': 'Motor conduction block', 'desc': 'label: Motor conduction block\ndefinition : Blockade of impulses at a focal site along the course of a motor axon.\nsynonyms :\n'}


{'id': 'HP_0012079', 'url': 'http://purl.obolibrary.org/obo/HP_0012079', 'lbl': 'Abnormality of central motor conduction', 'desc': 'label: Abnormality of central motor conduction\ndefinition : Any anomaly of the conduction of motor nerve impulses in the central nervous system.\nsynonyms :\n'}


{'id': 'HP_0012080', 'url': 'http://purl.obolibrary.org/obo/HP_0012080', 'lbl': 'Cerebellar granular layer atrophy', 'desc': 'label: Cerebellar granular layer atrophy\ndefinition : Atrophy of the cerebellum affecting primarily the granular cell layer.\nsynonyms :\n'}


{'id': 'HP_0012081', 'url': 'http://purl.obolibrary.org/obo/HP_0012081', 'lbl': 'Enlarged cerebellum', 'desc': 'label: Enlarged cerebellum\ndefinition : An abnormally increased size of the cerebellum compared to other brain structures.\nsynonyms :\n'}


{'id': 'HP_0012082', 'url': 'http://purl.obolibrary.org/obo/HP_0012082', 'lbl': 'Cerebellar Purkinje layer atrophy', 'desc': 'label: Cerebellar Purkinje layer atrophy\ndefinition : Atrophy of the cerebellum affecting primarily the Purkinje cell layer.\nsynonyms :\n'}


{'id': 'HP_0012083', 'url': 'http://purl.obolibrary.org/obo/HP_0012083', 'lbl': 'Ubiquitin-positive cerebral inclusion bodies', 'desc': 'label: Ubiquitin-positive cerebral inclusion bodies\ndefinition : Nuclear or cytoplasmic aggregates that show positive staining with antibodies against ubiquitin within cells of the brain.\nsynonyms :\n'}


{'id': 'HP_0012084', 'url': 'http://purl.obolibrary.org/obo/HP_0012084', 'lbl': 'Abnormality of skeletal muscle fiber size', 'desc': 'label: Abnormality of skeletal muscle fiber size\ndefinition : Any abnormality of the size of the skeletal muscle cell.\nsynonyms :Abnormality of skeletal muscle fibre size\n'}


{'id': 'HP_0012085', 'url': 'http://purl.obolibrary.org/obo/HP_0012085', 'lbl': 'Pyuria', 'desc': 'label: Pyuria\ndefinition : The presence of 10 or more white cells per cubic millimeter in a urine specimen, 3 or more white cells per high-power field of unspun urine, a positive result on Gram staining of an unspun urine specimen, or a urinary dipstick test that is positive for leukocyte esterase.\nsynonyms :High urine neutrophil count; Leukocyturia\n'}


{'id': 'HP_0012086', 'url': 'http://purl.obolibrary.org/obo/HP_0012086', 'lbl': 'Abnormal urinary color', 'desc': 'label: Abnormal urinary color\ndefinition : An abnormal color of the urine, that is, the color of the urine appears different from the usual straw-yellow color.\nsynonyms :Abnormal urinary color; Abnormal urinary colour; Abnormal urine color; Abnormal urine colour\n'}


{'id': 'HP_0012087', 'url': 'http://purl.obolibrary.org/obo/HP_0012087', 'lbl': 'Abnormal mitochondrial shape', 'desc': 'label: Abnormal mitochondrial shape\ndefinition : An anomaly in the surface contour of mitochondria.\nsynonyms :\n'}


{'id': 'HP_0012088', 'url': 'http://purl.obolibrary.org/obo/HP_0012088', 'lbl': 'Abnormal urinary odor', 'desc': 'label: Abnormal urinary odor\ndefinition : A deviation from the normal odor of the urine.\nsynonyms :Abnormal urinary odor; Abnormal urinary odour; Abnormal urine smell\n'}


{'id': 'HP_0012089', 'url': 'http://purl.obolibrary.org/obo/HP_0012089', 'lbl': 'Arteritis', 'desc': 'label: Arteritis\ndefinition : Arterial inflammation.\nsynonyms :Inflammation of artery\n'}


{'id': 'HP_0012090', 'url': 'http://purl.obolibrary.org/obo/HP_0012090', 'lbl': 'Abnormal pancreas morphology', 'desc': 'label: Abnormal pancreas morphology\ndefinition : \nsynonyms :Abnormality of pancreas morphology; Abnormally shaped pancreas\n'}


{'id': 'HP_0012091', 'url': 'http://purl.obolibrary.org/obo/HP_0012091', 'lbl': 'Abnormality of pancreas physiology', 'desc': 'label: Abnormality of pancreas physiology\ndefinition : An anomaly of the function of the pancreas.\nsynonyms :\n'}


{'id': 'HP_0012092', 'url': 'http://purl.obolibrary.org/obo/HP_0012092', 'lbl': 'Abnormality of exocrine pancreas physiology', 'desc': 'label: Abnormality of exocrine pancreas physiology\ndefinition : A functional anomaly of the acinar gland portion of the pancreas that secretes digestive enzymes.\nsynonyms :Abnormal exocrine pancreatic function\n'}


{'id': 'HP_0012093', 'url': 'http://purl.obolibrary.org/obo/HP_0012093', 'lbl': 'Abnormality of endocrine pancreas physiology', 'desc': 'label: Abnormality of endocrine pancreas physiology\ndefinition : A function abnormality of the endocrine pancreas.\nsynonyms :\n'}


{'id': 'HP_0012094', 'url': 'http://purl.obolibrary.org/obo/HP_0012094', 'lbl': 'Abnormal pancreas size', 'desc': 'label: Abnormal pancreas size\ndefinition : A deviation from the normal size of the pancreas.\nsynonyms :Abnormal pancreas size\n'}


{'id': 'HP_0012095', 'url': 'http://purl.obolibrary.org/obo/HP_0012095', 'lbl': 'Multiple joint dislocation', 'desc': 'label: Multiple joint dislocation\ndefinition : Dislocation of many joints.\nsynonyms :Multiple joint dislocations\n'}


{'id': 'HP_0012096', 'url': 'http://purl.obolibrary.org/obo/HP_0012096', 'lbl': 'Intracranial epidermoid cyst', 'desc': 'label: Intracranial epidermoid cyst\ndefinition : A congenital inclusion cysts that arises from ectodermal cells that normally form skin cells being left behind in the nervous system during development.\nsynonyms :\n'}


{'id': 'HP_0012097', 'url': 'http://purl.obolibrary.org/obo/HP_0012097', 'lbl': 'Intracranial dermoid cyst', 'desc': 'label: Intracranial dermoid cyst\ndefinition : A congenital inclusion cysts that arises from the inclusion of ectodermally committed cells at the time of neural tube closure (3rd-5th week of embryogenesis). The capsule of dermoid cysts consists of simple epithelium supported by collagen. In thicker parts, the lining is supplemented with dermis containing hair follicles, sebaceous glands, and apocrine glands.\nsynonyms :\n'}


{'id': 'HP_0012098', 'url': 'http://purl.obolibrary.org/obo/HP_0012098', 'lbl': 'Edema of the dorsum of feet', 'desc': 'label: Edema of the dorsum of feet\ndefinition : An abnormal accumulation of fluid beneath the skin on the back of the feet.\nsynonyms :Edema of dorsum of feet; Oedema of dorsum of feet; Oedema of the dorsum of feet\n'}


{'id': 'HP_0012099', 'url': 'http://purl.obolibrary.org/obo/HP_0012099', 'lbl': 'Abnormality of circulating catecholamine level', 'desc': 'label: Abnormality of circulating catecholamine level\ndefinition : An abnormal catecholamine concentration in the blood.\nsynonyms :Catecholamine levels abnormal\n'}


{'id': 'HP_0012100', 'url': 'http://purl.obolibrary.org/obo/HP_0012100', 'lbl': 'Abnormal circulating creatinine concentration', 'desc': 'label: Abnormal circulating creatinine concentration\ndefinition : An abnormal concentration of creatinine in the blood.\nsynonyms :Abnormal blood creatinine level; Abnormal circulating creatinine level; Creatinine levels abnormal\n'}


{'id': 'HP_0012101', 'url': 'http://purl.obolibrary.org/obo/HP_0012101', 'lbl': 'Decreased serum creatinine', 'desc': 'label: Decreased serum creatinine\ndefinition : An abnormally reduced amount of creatinine in the blood.\nsynonyms :Decreased serum creatinine; Low blood creatinine level; Reduced creatinine levels\n'}


{'id': 'HP_0012102', 'url': 'http://purl.obolibrary.org/obo/HP_0012102', 'lbl': 'Abnormal mitochondrial number', 'desc': 'label: Abnormal mitochondrial number\ndefinition : A deviation from the normal number of mitochondria per cell.\nsynonyms :\n'}


{'id': 'HP_0012103', 'url': 'http://purl.obolibrary.org/obo/HP_0012103', 'lbl': 'Abnormality of the mitochondrion', 'desc': 'label: Abnormality of the mitochondrion\ndefinition : An anomaly of the mitochondrion, the membranous cytoplasmic organelle the interior of which is subdivided by cristae. The mitochondrion is a self replicating organelle that is the site of tissue respiration.\nsynonyms :Mitochondrial abnormalities\n'}


{'id': 'HP_0012104', 'url': 'http://purl.obolibrary.org/obo/HP_0012104', 'lbl': 'Parietal cortical atrophy', 'desc': 'label: Parietal cortical atrophy\ndefinition : Atrophy of the parietal cortex.\nsynonyms :\n'}


{'id': 'HP_0012105', 'url': 'http://purl.obolibrary.org/obo/HP_0012105', 'lbl': 'Occipital cortical atrophy', 'desc': 'label: Occipital cortical atrophy\ndefinition : Atrophy of the occipital cortex.\nsynonyms :\n'}


{'id': 'HP_0012106', 'url': 'http://purl.obolibrary.org/obo/HP_0012106', 'lbl': 'Rhizomelic leg shortening', 'desc': 'label: Rhizomelic leg shortening\ndefinition : Disproportionate shortening of the proximal segment of the leg (i.e. the femur).\nsynonyms :\n'}


{'id': 'HP_0012107', 'url': 'http://purl.obolibrary.org/obo/HP_0012107', 'lbl': 'Increased fibular diameter', 'desc': 'label: Increased fibular diameter\ndefinition : Increased width of the cross sectional diameter of the fibula.\nsynonyms :Thick fibula; Thick fibulae; Wide calf bone; Wide fibula\n'}


{'id': 'HP_0012108', 'url': 'http://purl.obolibrary.org/obo/HP_0012108', 'lbl': 'Open angle glaucoma', 'desc': 'label: Open angle glaucoma\ndefinition : A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,\nsynonyms :Primary open angle glaucoma\n'}


{'id': 'HP_0012109', 'url': 'http://purl.obolibrary.org/obo/HP_0012109', 'lbl': 'Angle closure glaucoma', 'desc': 'label: Angle closure glaucoma\ndefinition : A type of glaucomatous optic neuropathy in an eye that has evidence of angle closure (i.e. significant iridotrabecular contact).\nsynonyms :Closed-angle glaucoma; Narrow angle glaucoma; Primary angle closure glaucoma\n'}


{'id': 'HP_0012110', 'url': 'http://purl.obolibrary.org/obo/HP_0012110', 'lbl': 'Hypoplasia of the pons', 'desc': 'label: Hypoplasia of the pons\ndefinition : Underdevelopment of the pons.\nsynonyms :Pontine hypoplasia\n'}


{'id': 'HP_0012111', 'url': 'http://purl.obolibrary.org/obo/HP_0012111', 'lbl': 'Abnormality of circulating glucocorticoid level', 'desc': 'label: Abnormality of circulating glucocorticoid level\ndefinition : An abnormality of the concentration of a glucocorticoid in the blood.\nsynonyms :\n'}


{'id': 'HP_0012112', 'url': 'http://purl.obolibrary.org/obo/HP_0012112', 'lbl': 'Abnormal circulating corticosterone level', 'desc': 'label: Abnormal circulating corticosterone level\ndefinition : An abnormality of the concentration of corticosterone in the blood.\nsynonyms :Abnormality of circulating corticosterone level\n'}


{'id': 'HP_0012113', 'url': 'http://purl.obolibrary.org/obo/HP_0012113', 'lbl': 'Abnormal circulating creatine concentration', 'desc': 'label: Abnormal circulating creatine concentration\ndefinition : A deviation from the normal concentration of creatine in the blood circulation. Creatine is a derivative of glycine having methyl and amidino groups attached to the nitrogen. Creatine is naturally produced from amino acids, primarily in liver and kidney, and acts as an energy source for cells, primarly for muscle cells.\nsynonyms :Abnormality of creatine metabolism; Creatine metabolism abnormal\n'}


{'id': 'HP_0012114', 'url': 'http://purl.obolibrary.org/obo/HP_0012114', 'lbl': 'Endometrial carcinoma', 'desc': 'label: Endometrial carcinoma\ndefinition : A carcinoma of the endometrium, the mucous lining of the uterus.\nsynonyms :\n'}


{'id': 'HP_0012115', 'url': 'http://purl.obolibrary.org/obo/HP_0012115', 'lbl': 'Hepatitis', 'desc': 'label: Hepatitis\ndefinition : Inflammation of the liver.\nsynonyms :Liver inflammation\n'}


{'id': 'HP_0012116', 'url': 'http://purl.obolibrary.org/obo/HP_0012116', 'lbl': 'Abnormal circulating albumin concentration', 'desc': 'label: Abnormal circulating albumin concentration\ndefinition : Deviation from normal concentration of albumin in the blood.\nsynonyms :Abnormal albumin level\n'}


{'id': 'HP_0012117', 'url': 'http://purl.obolibrary.org/obo/HP_0012117', 'lbl': 'Hyperalbuminemia', 'desc': 'label: Hyperalbuminemia\ndefinition : Elevation in the concentration of albumin in the blood.\nsynonyms :High albumin; High blood albumin levels; Hyperalbuminaemia\n'}


{'id': 'HP_0012118', 'url': 'http://purl.obolibrary.org/obo/HP_0012118', 'lbl': 'Laryngeal carcinoma', 'desc': 'label: Laryngeal carcinoma\ndefinition : A carcinoma of the larynx.\nsynonyms :Cancer of the larynx; Laryngeal cancer\n'}


{'id': 'HP_0012119', 'url': 'http://purl.obolibrary.org/obo/HP_0012119', 'lbl': 'Methemoglobinemia', 'desc': 'label: Methemoglobinemia\ndefinition : Abnormally increased levels of methemoglobin in the blood. In this form of hemoglobin, there is an oxidized ferric iron (Fe +3) rather than the reduced ferrous form (Fe 2+) that is normally found in hemoglobin. Methemoglobin has a reduced affinity for oxygen, resulting in a reduced ability to release oxygen to tissues.\nsynonyms :\n'}


{'id': 'HP_0012120', 'url': 'http://purl.obolibrary.org/obo/HP_0012120', 'lbl': 'Methylmalonic aciduria', 'desc': 'label: Methylmalonic aciduria\ndefinition : Increased concentration of methylmalonic acid in the urine.\nsynonyms :High blood methylmalonic acid levels; Methymalonicaciduria\n'}


{'id': 'HP_0012121', 'url': 'http://purl.obolibrary.org/obo/HP_0012121', 'lbl': 'Panuveitis', 'desc': 'label: Panuveitis\ndefinition : Inflammation of the uveal tract in which inflammation affects the anterior chamber, vitreous, retina or choroid.\nsynonyms :\n'}


{'id': 'HP_0012122', 'url': 'http://purl.obolibrary.org/obo/HP_0012122', 'lbl': 'Anterior uveitis', 'desc': 'label: Anterior uveitis\ndefinition : Inflammation of the uveal tract in which the primary site of inflammation is the anterior chamber.\nsynonyms :\n'}


{'id': 'HP_0012123', 'url': 'http://purl.obolibrary.org/obo/HP_0012123', 'lbl': 'Posterior uveitis', 'desc': 'label: Posterior uveitis\ndefinition : Inflammation of the uveal tract in which the primary site of inflammation is the retina or choroid.\nsynonyms :Choroiditis\n'}


{'id': 'HP_0012124', 'url': 'http://purl.obolibrary.org/obo/HP_0012124', 'lbl': 'Intermediate uveitis', 'desc': 'label: Intermediate uveitis\ndefinition : Inflammation of the uveal tract in which the primary site of inflammation is the vitreous.\nsynonyms :\n'}


{'id': 'HP_0012125', 'url': 'http://purl.obolibrary.org/obo/HP_0012125', 'lbl': 'Prostate cancer', 'desc': 'label: Prostate cancer\ndefinition : A cancer of the prostate.\nsynonyms :Prostatic cancer\n'}


{'id': 'HP_0012126', 'url': 'http://purl.obolibrary.org/obo/HP_0012126', 'lbl': 'Stomach cancer', 'desc': 'label: Stomach cancer\ndefinition : A cancer arising in any part of the stomach.\nsynonyms :Gastric cancer\n'}


{'id': 'HP_0012127', 'url': 'http://purl.obolibrary.org/obo/HP_0012127', 'lbl': 'Uraciluria', 'desc': 'label: Uraciluria\ndefinition : Increased concentration of uracil in the urine.\nsynonyms :High urine uracil levels\n'}


{'id': 'HP_0012128', 'url': 'http://purl.obolibrary.org/obo/HP_0012128', 'lbl': 'Basal ganglia necrosis', 'desc': 'label: Basal ganglia necrosis\ndefinition : Death of cells in the basal ganglia.\nsynonyms :\n'}


{'id': 'HP_0012129', 'url': 'http://purl.obolibrary.org/obo/HP_0012129', 'lbl': 'Abnormality of bone marrow stromal cells', 'desc': 'label: Abnormality of bone marrow stromal cells\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012130', 'url': 'http://purl.obolibrary.org/obo/HP_0012130', 'lbl': 'Abnormal erythroid lineage cell morphology', 'desc': 'label: Abnormal erythroid lineage cell morphology\ndefinition : An anomaly of erythroid lineage cells, that is, of the erythropoietic cells in the lineage leading to and including erythrocytes.\nsynonyms :Abnormality of cells of the erythroid lineage\n'}


{'id': 'HP_0012131', 'url': 'http://purl.obolibrary.org/obo/HP_0012131', 'lbl': 'Abnormal number of erythroid precursors', 'desc': 'label: Abnormal number of erythroid precursors\ndefinition : A deviation from the normal count of erythroid precursor cells, that is, erythroid lineage cells in the bone marrow.\nsynonyms :\n'}


{'id': 'HP_0012132', 'url': 'http://purl.obolibrary.org/obo/HP_0012132', 'lbl': 'Erythroid hyperplasia', 'desc': 'label: Erythroid hyperplasia\ndefinition : Increased count of erythroid precursor cells, that is, erythroid lineage cells in the bone marrow.\nsynonyms :Bone marrow biopsy shows erythroid hyperplasia; Bone marrow smear shows erythroid hyperplasia\n'}


{'id': 'HP_0012133', 'url': 'http://purl.obolibrary.org/obo/HP_0012133', 'lbl': 'Erythroid hypoplasia', 'desc': 'label: Erythroid hypoplasia\ndefinition : Decreased count of erythroid precursor cells, that is, erythroid lineage cells in the bone marrow.\nsynonyms :Erythroblastopenia; Erythroid hypoplasia in the bone marrow\n'}


{'id': 'HP_0012134', 'url': 'http://purl.obolibrary.org/obo/HP_0012134', 'lbl': 'Dysplastic erythropoesis', 'desc': 'label: Dysplastic erythropoesis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012135', 'url': 'http://purl.obolibrary.org/obo/HP_0012135', 'lbl': 'Abnormal granulocytopoietic cell morphology', 'desc': 'label: Abnormal granulocytopoietic cell morphology\ndefinition : An anomaly of cells involved in the formation of a granulocytes, that is, of the granulocytopoietic cell.\nsynonyms :Abnormality of cells of the granulocytic lineage\n'}


{'id': 'HP_0012136', 'url': 'http://purl.obolibrary.org/obo/HP_0012136', 'lbl': 'Dysplastic granulopoesis', 'desc': 'label: Dysplastic granulopoesis\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012137', 'url': 'http://purl.obolibrary.org/obo/HP_0012137', 'lbl': 'Abnormal number of granulocyte precursors', 'desc': 'label: Abnormal number of granulocyte precursors\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012138', 'url': 'http://purl.obolibrary.org/obo/HP_0012138', 'lbl': 'Granulocytic hyperplasia', 'desc': 'label: Granulocytic hyperplasia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012139', 'url': 'http://purl.obolibrary.org/obo/HP_0012139', 'lbl': 'Granulocytic hypoplasia', 'desc': 'label: Granulocytic hypoplasia\ndefinition : Decreased number of granulocyte precursors in the bone marrow.\nsynonyms :\n'}


{'id': 'HP_0012140', 'url': 'http://purl.obolibrary.org/obo/HP_0012140', 'lbl': 'obsolete Abnormality of cells of the lymphoid lineage', 'desc': 'label: obsolete Abnormality of cells of the lymphoid lineage\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012142', 'url': 'http://purl.obolibrary.org/obo/HP_0012142', 'lbl': 'Pancreatic squamous cell carcinoma', 'desc': 'label: Pancreatic squamous cell carcinoma\ndefinition : A subtype of ductal pancreatic carcinoma that is thought to originate from squamous metaplasia of pancreatic ductal epithelium.\nsynonyms :Squamous cell carcinoma of the pancreas\n'}


{'id': 'HP_0012143', 'url': 'http://purl.obolibrary.org/obo/HP_0012143', 'lbl': 'Abnormal megakaryocyte morphology', 'desc': 'label: Abnormal megakaryocyte morphology\ndefinition : Any structural anomaly of megakaryocytes. Mature blood platelets are released from the cytoplasm of megakaryocytes, which are bone-marrow resident cells.\nsynonyms :Abnormality of cells of the megakaryocyte lineage\n'}


{'id': 'HP_0012144', 'url': 'http://purl.obolibrary.org/obo/HP_0012144', 'lbl': 'Abnormal monocyte morphology', 'desc': 'label: Abnormal monocyte morphology\ndefinition : Any structural anomaly of a myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.\nsynonyms :\n'}


{'id': 'HP_0012145', 'url': 'http://purl.obolibrary.org/obo/HP_0012145', 'lbl': 'Abnormality of multiple cell lineages in the bone marrow', 'desc': 'label: Abnormality of multiple cell lineages in the bone marrow\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012146', 'url': 'http://purl.obolibrary.org/obo/HP_0012146', 'lbl': 'Abnormality of von Willebrand factor', 'desc': 'label: Abnormality of von Willebrand factor\ndefinition : Decreased quantity or activity of von Willebrand factor. Von Willebrand factor mediates the adhesion of platelets to the collagen exposed on endothelial cell surfaces.\nsynonyms :\n'}


{'id': 'HP_0012147', 'url': 'http://purl.obolibrary.org/obo/HP_0012147', 'lbl': 'Reduced quantity of Von Willebrand factor', 'desc': 'label: Reduced quantity of Von Willebrand factor\ndefinition : Decreased quantity of von Willebrand factor.\nsynonyms :Decreased von Willebrand factor\n'}


{'id': 'HP_0012148', 'url': 'http://purl.obolibrary.org/obo/HP_0012148', 'lbl': 'Multiple lineage myelodysplasia', 'desc': 'label: Multiple lineage myelodysplasia\ndefinition : Myelodysplasia with dysplastic changes in two or more of the myeloid lineages: erythroid, granulocytic, megakaryocytic.\nsynonyms :\n'}


{'id': 'HP_0012149', 'url': 'http://purl.obolibrary.org/obo/HP_0012149', 'lbl': 'Bilineage myelodysplasia', 'desc': 'label: Bilineage myelodysplasia\ndefinition : Myelodysplasia with dysplastic changes in two of the myeloid lineages: erythroid, granulocytic, megakaryocytic.\nsynonyms :\n'}


{'id': 'HP_0012150', 'url': 'http://purl.obolibrary.org/obo/HP_0012150', 'lbl': 'Single lineage myelodysplasia', 'desc': 'label: Single lineage myelodysplasia\ndefinition : Abnormality/dysplasia of a single myeloid cell (erythroid, granulocytic, or megakaryocytic).\nsynonyms :\n'}


{'id': 'HP_0012151', 'url': 'http://purl.obolibrary.org/obo/HP_0012151', 'lbl': 'Hemothorax', 'desc': 'label: Hemothorax\ndefinition : The presence of blood in the pleural space.\nsynonyms :\n'}


{'id': 'HP_0012152', 'url': 'http://purl.obolibrary.org/obo/HP_0012152', 'lbl': 'Foveoschisis', 'desc': 'label: Foveoschisis\ndefinition : Splitting of the retinal layers in the macula.\nsynonyms :Retinoschisis involving the fovea\n'}


{'id': 'HP_0012153', 'url': 'http://purl.obolibrary.org/obo/HP_0012153', 'lbl': 'Hypotriglyceridemia', 'desc': 'label: Hypotriglyceridemia\ndefinition : An decrease in the level of triglycerides in the blood.\nsynonyms :Decreased circulating Tg levels; Decreased plasma Tg levels; Low blood triglyceride levels\n'}


{'id': 'HP_0012154', 'url': 'http://purl.obolibrary.org/obo/HP_0012154', 'lbl': 'Anhedonia', 'desc': 'label: Anhedonia\ndefinition : Inability to experience pleasure activities usually found enjoyable.\nsynonyms :\n'}


{'id': 'HP_0012155', 'url': 'http://purl.obolibrary.org/obo/HP_0012155', 'lbl': 'Decreased corneal sensation', 'desc': 'label: Decreased corneal sensation\ndefinition : Reduced ability of the cornea to respond to stimulation.\nsynonyms :Corneal hypaesthesia; Corneal hypesthesia; Reduced corneal sensation; Decreased corneal sensitivity\n'}


{'id': 'HP_0012156', 'url': 'http://purl.obolibrary.org/obo/HP_0012156', 'lbl': 'Hemophagocytosis', 'desc': 'label: Hemophagocytosis\ndefinition : Phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and other tissues.\nsynonyms :\n'}


{'id': 'HP_0012157', 'url': 'http://purl.obolibrary.org/obo/HP_0012157', 'lbl': 'Subcortical cerebral atrophy', 'desc': 'label: Subcortical cerebral atrophy\ndefinition : Atrophy of the cerebral subcortical white and gray matter, termed subcortical atrophy, reflects loss of nerve cells in the basal ganglia or fibers in the deep white matter.\nsynonyms :\n'}


{'id': 'HP_0012158', 'url': 'http://purl.obolibrary.org/obo/HP_0012158', 'lbl': 'Carotid artery dissection', 'desc': 'label: Carotid artery dissection\ndefinition : A separation (dissection) of the layers of the carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0012159', 'url': 'http://purl.obolibrary.org/obo/HP_0012159', 'lbl': 'Internal carotid artery dissection', 'desc': 'label: Internal carotid artery dissection\ndefinition : A separation (dissection) of the layers of the internal carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0012160', 'url': 'http://purl.obolibrary.org/obo/HP_0012160', 'lbl': 'Intracranial internal carotid artery dissection', 'desc': 'label: Intracranial internal carotid artery dissection\ndefinition : A separation (dissection) of the layers of the intracranial portion of the internal carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0012161', 'url': 'http://purl.obolibrary.org/obo/HP_0012161', 'lbl': 'External carotid artery dissection', 'desc': 'label: External carotid artery dissection\ndefinition : A separation (dissection) of the layers of the external carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0012162', 'url': 'http://purl.obolibrary.org/obo/HP_0012162', 'lbl': 'Common carotid artery dissection', 'desc': 'label: Common carotid artery dissection\ndefinition : A separation (dissection) of the layers of the common carotid artery wall.\nsynonyms :\n'}


{'id': 'HP_0012163', 'url': 'http://purl.obolibrary.org/obo/HP_0012163', 'lbl': 'Carotid artery dilatation', 'desc': 'label: Carotid artery dilatation\ndefinition : A dilatation (balooning or bulging out of the vessel wall) of a carotid artery.\nsynonyms :Carotid artery aneurysm\n'}


{'id': 'HP_0012164', 'url': 'http://purl.obolibrary.org/obo/HP_0012164', 'lbl': 'Asterixis', 'desc': 'label: Asterixis\ndefinition : A clinical sign indicating a lapse of posture and is usually manifest by a bilateral flapping tremor at the wrist, metacarpophalangeal, and hip joints.\nsynonyms :\n'}


{'id': 'HP_0012165', 'url': 'http://purl.obolibrary.org/obo/HP_0012165', 'lbl': 'Oligodactyly', 'desc': 'label: Oligodactyly\ndefinition : A developmental defect resulting in the presence of fewer than the normal number of digits.\nsynonyms :\n'}


{'id': 'HP_0012166', 'url': 'http://purl.obolibrary.org/obo/HP_0012166', 'lbl': 'Skin-picking', 'desc': 'label: Skin-picking\ndefinition : Repetitive and compulsive picking of skin which results in tissue damage.\nsynonyms :Compulsive skin picking; Dermatillomania\n'}


{'id': 'HP_0012167', 'url': 'http://purl.obolibrary.org/obo/HP_0012167', 'lbl': 'Hair-pulling', 'desc': 'label: Hair-pulling\ndefinition : A phenomenon in which persons repetitively pull out their own hair, resulting in noticeable hair loss.\nsynonyms :Trichotillomania\n'}


{'id': 'HP_0012168', 'url': 'http://purl.obolibrary.org/obo/HP_0012168', 'lbl': 'Head-banging', 'desc': "label: Head-banging\ndefinition : Habitual striking of one's own head against a surface such as a mattress or wall of a crib.\nsynonyms :\n"}


{'id': 'HP_0012169', 'url': 'http://purl.obolibrary.org/obo/HP_0012169', 'lbl': 'Self-biting', 'desc': "label: Self-biting\ndefinition : Habitual biting of one's own body.\nsynonyms :\n"}


{'id': 'HP_0012170', 'url': 'http://purl.obolibrary.org/obo/HP_0012170', 'lbl': 'Nail-biting', 'desc': "label: Nail-biting\ndefinition : Habitual biting of one's own fingernails.\nsynonyms :Nail-biting; Onychophagia; Onychophagy\n"}


{'id': 'HP_0012171', 'url': 'http://purl.obolibrary.org/obo/HP_0012171', 'lbl': 'Stereotypical hand wringing', 'desc': 'label: Stereotypical hand wringing\ndefinition : Habitual clasping and squeezing of the hands.\nsynonyms :Hand clasping; Hand-wringing; Handwringing\n'}


{'id': 'HP_0012172', 'url': 'http://purl.obolibrary.org/obo/HP_0012172', 'lbl': 'Stereotypical body rocking', 'desc': 'label: Stereotypical body rocking\ndefinition : Habitual repetitive movement of the entire body.\nsynonyms :\n'}


{'id': 'HP_0012173', 'url': 'http://purl.obolibrary.org/obo/HP_0012173', 'lbl': 'Orthostatic tachycardia', 'desc': 'label: Orthostatic tachycardia\ndefinition : An increase in heart rate with standing of 30 beats per minute or more.\nsynonyms :Postural tachycardia\n'}


{'id': 'HP_0012174', 'url': 'http://purl.obolibrary.org/obo/HP_0012174', 'lbl': 'Glioblastoma multiforme', 'desc': 'label: Glioblastoma multiforme\ndefinition : A tumor arising from glia in the central nervous system with macroscopic regions of necrosis and hemorrhage. Microscopically, glioblastoma multiforme is characterized by regions of pseudopalisading necrosis, pleomorphic nuclei and cells, and microvascular proliferation.\nsynonyms :Glioblastoma\n'}


{'id': 'HP_0012175', 'url': 'http://purl.obolibrary.org/obo/HP_0012175', 'lbl': 'Resistance to activated protein C', 'desc': "label: Resistance to activated protein C\ndefinition : Poor anticoagulant response to activated protein C. A plasma is termed 'APC resistant' when the addition of exogenous APC fails to prolong its clotting time in an activated partial thromboplastin time assay.\nsynonyms :Activated protein C resistance\n"}


{'id': 'HP_0012176', 'url': 'http://purl.obolibrary.org/obo/HP_0012176', 'lbl': 'Abnormal natural killer cell morphology', 'desc': 'label: Abnormal natural killer cell morphology\ndefinition : An anomaly of the natural killer cell, which is a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors. It also regulates immune responses via cytokine release and direct contact with other cells.\nsynonyms :Abnormal NK cells; Abnormality of natural killer cells\n'}


{'id': 'HP_0012177', 'url': 'http://purl.obolibrary.org/obo/HP_0012177', 'lbl': 'Abnormal natural killer cell physiology', 'desc': 'label: Abnormal natural killer cell physiology\ndefinition : A functional anomaly of the natural killer cell.\nsynonyms :\n'}


{'id': 'HP_0012178', 'url': 'http://purl.obolibrary.org/obo/HP_0012178', 'lbl': 'Reduced natural killer cell activity', 'desc': 'label: Reduced natural killer cell activity\ndefinition : Reduced ability of the natural killer cell to function in the adaptive immune response.\nsynonyms :\n'}


{'id': 'HP_0012179', 'url': 'http://purl.obolibrary.org/obo/HP_0012179', 'lbl': 'Craniofacial dystonia', 'desc': 'label: Craniofacial dystonia\ndefinition : A form of focal dystonia affecting the face and especially the jaw that is induced by the act of speaking. It is an involuntary contraction of the masticatory muscles, resulting in dysarthria or dysphagia.\nsynonyms :Abnormal craniofacial posture; Distorted craniofacial posture; Abnormal craniofacial muscle tone; Abnormal facial muscle tone; Facial Dystonia\n'}


{'id': 'HP_0012180', 'url': 'http://purl.obolibrary.org/obo/HP_0012180', 'lbl': 'Cystic medial necrosis', 'desc': 'label: Cystic medial necrosis\ndefinition : A disorder of large arteries, in particular the aorta, characterized by an accumulation of basophilic ground substance in the media with cyst-like lesions associated with degenerative changes of collagen, elastin and the vascular smooth muscle cells.\nsynonyms :Arterial cystic medial necrosis\n'}


{'id': 'HP_0012181', 'url': 'http://purl.obolibrary.org/obo/HP_0012181', 'lbl': 'Entrapment neuropathy', 'desc': 'label: Entrapment neuropathy\ndefinition : Malfunction of a peripheral nerve resulting from mechanical compression of the nerve roots from internal or external causes and leading to a conduction block or axonal loss.\nsynonyms :\n'}


{'id': 'HP_0012182', 'url': 'http://purl.obolibrary.org/obo/HP_0012182', 'lbl': 'Oropharyngeal squamous cell carcinoma', 'desc': 'label: Oropharyngeal squamous cell carcinoma\ndefinition : A squamous cell carcinoma that originates in the oropharnyx.\nsynonyms :\n'}


{'id': 'HP_0012183', 'url': 'http://purl.obolibrary.org/obo/HP_0012183', 'lbl': 'Hyperplastic colonic polyposis', 'desc': 'label: Hyperplastic colonic polyposis\ndefinition : Presence of multiple hyperplastic polyps in the colon. Hyperplastic polyps are generally about 5 mm in size and show hyperplastic mucosal proliferation.\nsynonyms :\n'}


{'id': 'HP_0012184', 'url': 'http://purl.obolibrary.org/obo/HP_0012184', 'lbl': 'Increased HDL cholesterol concentration', 'desc': 'label: Increased HDL cholesterol concentration\ndefinition : An elevated concentration of high-density lipoprotein cholesterol (HDL) in the blood.\nsynonyms :High blood HDL level; Hyperalphalipoproteinemia; Increased circulating high-density lipoprotein levels\n'}


{'id': 'HP_0012185', 'url': 'http://purl.obolibrary.org/obo/HP_0012185', 'lbl': 'Constrictive median neuropathy', 'desc': 'label: Constrictive median neuropathy\ndefinition : Injury to the median nerve caused by its entrapment at the wrist as it traverses through the carpal tunnel. Clinically, constrictive median neuropathy is characterized by pain, paresthesia, and weakness in the median nerve distribution of the hand.\nsynonyms :Carpal tunnel syndrome\n'}


{'id': 'HP_0012186', 'url': 'http://purl.obolibrary.org/obo/HP_0012186', 'lbl': 'Entrapment neuropathy of the ulnar nerve at elbow', 'desc': 'label: Entrapment neuropathy of the ulnar nerve at elbow\ndefinition : An entrapment neuropathy of the ulnar nerve in the cubital tunnel (in the elbow) characterized by numbness in the ring and little fingers and weakness of the intrinsic muscles in the hand.\nsynonyms :\n'}


{'id': 'HP_0012187', 'url': 'http://purl.obolibrary.org/obo/HP_0012187', 'lbl': 'Increased erythrocyte protoporphyrin concentration', 'desc': 'label: Increased erythrocyte protoporphyrin concentration\ndefinition : An increased concentration of protoporphyrins in erythrocytes.\nsynonyms :\n'}


{'id': 'HP_0012188', 'url': 'http://purl.obolibrary.org/obo/HP_0012188', 'lbl': 'Hyperemesis gravidarum', 'desc': 'label: Hyperemesis gravidarum\ndefinition : Excessive vomiting in early pregnancy, leading to the loss of 5% or more of body weight.\nsynonyms :\n'}


{'id': 'HP_0012189', 'url': 'http://purl.obolibrary.org/obo/HP_0012189', 'lbl': 'Hodgkin lymphoma', 'desc': "label: Hodgkin lymphoma\ndefinition : A type of lymphoma characterized microscopically by multinucleated Reed-Sternberg cells.\nsynonyms :Hodgkin disease; Hodgkin's lymphoma\n"}


{'id': 'HP_0012190', 'url': 'http://purl.obolibrary.org/obo/HP_0012190', 'lbl': 'T-cell lymphoma', 'desc': 'label: T-cell lymphoma\ndefinition : A type of lymphoma that originates in T-cells.\nsynonyms :T cell lymphoma\n'}


{'id': 'HP_0012191', 'url': 'http://purl.obolibrary.org/obo/HP_0012191', 'lbl': 'B-cell lymphoma', 'desc': 'label: B-cell lymphoma\ndefinition : A type of lymphoma that originates in B-cells.\nsynonyms :B cell lymphoma\n'}


{'id': 'HP_0012192', 'url': 'http://purl.obolibrary.org/obo/HP_0012192', 'lbl': 'Cutaneous T-cell lymphoma', 'desc': 'label: Cutaneous T-cell lymphoma\ndefinition : A type of T-cell lymphoma that exhibits malignant infiltration of the skin.\nsynonyms :\n'}


{'id': 'HP_0012193', 'url': 'http://purl.obolibrary.org/obo/HP_0012193', 'lbl': 'Anaplastic large-cell lymphoma', 'desc': 'label: Anaplastic large-cell lymphoma\ndefinition : A type of T-cell lymphoma that is characterized by so-called hallmark cells with a pleomorphic appearance that express the CD30 antigen, are lobulated, and have indented nuclei.\nsynonyms :\n'}


{'id': 'HP_0012194', 'url': 'http://purl.obolibrary.org/obo/HP_0012194', 'lbl': 'Episodic hemiplegia', 'desc': 'label: Episodic hemiplegia\ndefinition : Transient episodes of weakness of the arm, leg, and in some cases the face on one side of the body.\nsynonyms :\n'}


{'id': 'HP_0012195', 'url': 'http://purl.obolibrary.org/obo/HP_0012195', 'lbl': 'Irregular respiration', 'desc': 'label: Irregular respiration\ndefinition : Uneven rhythm of breathing.\nsynonyms :Irregular respiratory rhythm\n'}


{'id': 'HP_0012196', 'url': 'http://purl.obolibrary.org/obo/HP_0012196', 'lbl': 'Cheyne-Stokes respiration', 'desc': 'label: Cheyne-Stokes respiration\ndefinition : An abnormal pattern of respiration characterized by cycles of respiration that are increasingly deeper then shallower with possible periods of apnea. Affected patients may display a 10 to 20 second episode of hypoventilation or apnea, followed by respiration of increased depth and frequency over the course of about one minute. The cycle repeats every 45 seconds to 3 minutes.\nsynonyms :Cheyne-Stokes breathing; Periodic respiration\n'}


{'id': 'HP_0012197', 'url': 'http://purl.obolibrary.org/obo/HP_0012197', 'lbl': 'Insulinoma', 'desc': 'label: Insulinoma\ndefinition : A type of tumor of the pancreatic beta cells that secretes excess insulin and can result in hypoglycemia.\nsynonyms :Pancreatic insulinoma\n'}


{'id': 'HP_0012198', 'url': 'http://purl.obolibrary.org/obo/HP_0012198', 'lbl': 'Juvenile colonic polyposis', 'desc': 'label: Juvenile colonic polyposis\ndefinition : The presence of more than 5 juvenile polyps of the colon. The term juvenile polyps refer to a special histopathology and not the age of onset as the polyp might be diagnosed at all ages. The juvenile polyp has a spherical appearance and is microscopically characterized by overgrowth of an oedematous lamina propria with inflammatory cells and cystic glands.\nsynonyms :\n'}


{'id': 'HP_0012199', 'url': 'http://purl.obolibrary.org/obo/HP_0012199', 'lbl': 'Cluster headache', 'desc': 'label: Cluster headache\ndefinition : A type of headache characterized by repeated attacks of unilateral pain lasting 15 to 180 minutes and associated with local autonomic signs.\nsynonyms :\n'}


{'id': 'HP_0012200', 'url': 'http://purl.obolibrary.org/obo/HP_0012200', 'lbl': 'Abnormality of prothrombin', 'desc': 'label: Abnormality of prothrombin\ndefinition : An anomaly of clotting factor II, which is known as prothrombin, a vitamin K-dependent proenzyme that functions in the blood coagulation cascade.\nsynonyms :\n'}


{'id': 'HP_0012201', 'url': 'http://purl.obolibrary.org/obo/HP_0012201', 'lbl': 'obsolete Reduced prothrombin activity', 'desc': 'label: obsolete Reduced prothrombin activity\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012202', 'url': 'http://purl.obolibrary.org/obo/HP_0012202', 'lbl': 'Increased serum bile acid concentration', 'desc': 'label: Increased serum bile acid concentration\ndefinition : An increase in the concentration of bile acid in the blood.\nsynonyms :\n'}


{'id': 'HP_0012203', 'url': 'http://purl.obolibrary.org/obo/HP_0012203', 'lbl': 'Onychomycosis', 'desc': 'label: Onychomycosis\ndefinition : A fungal infection of the toenails or fingernails that tends to cause the nails to thicken, discolor, disfigure, and split.\nsynonyms :\n'}


{'id': 'HP_0012204', 'url': 'http://purl.obolibrary.org/obo/HP_0012204', 'lbl': 'Recurrent vulvovaginal candidiasis', 'desc': 'label: Recurrent vulvovaginal candidiasis\ndefinition : Recurrent infection involving the vulva, vagina, and adjacent crural areas, whereby the causative agent belongs to the genus Candida.\nsynonyms :\n'}


{'id': 'HP_0012205', 'url': 'http://purl.obolibrary.org/obo/HP_0012205', 'lbl': 'Globozoospermia', 'desc': 'label: Globozoospermia\ndefinition : Any structural anomaly of the acrosome resulting in a round sperm head.\nsynonyms :\n'}


{'id': 'HP_0012206', 'url': 'http://purl.obolibrary.org/obo/HP_0012206', 'lbl': 'Abnormal sperm motility', 'desc': 'label: Abnormal sperm motility\ndefinition : An anomaly of the mobility of ejaculated sperm.\nsynonyms :Abnormal sperm motility\n'}


{'id': 'HP_0012207', 'url': 'http://purl.obolibrary.org/obo/HP_0012207', 'lbl': 'Reduced sperm motility', 'desc': 'label: Reduced sperm motility\ndefinition : An abnormal reduction in the mobility of ejaculated sperm.\nsynonyms :Asthenospermia; Reduced sperm motility\n'}


{'id': 'HP_0012208', 'url': 'http://purl.obolibrary.org/obo/HP_0012208', 'lbl': 'Immotile sperm', 'desc': 'label: Immotile sperm\ndefinition : A lack of mobility of ejaculated sperm.\nsynonyms :Nonmotile sperm\n'}


{'id': 'HP_0012209', 'url': 'http://purl.obolibrary.org/obo/HP_0012209', 'lbl': 'Juvenile myelomonocytic leukemia', 'desc': 'label: Juvenile myelomonocytic leukemia\ndefinition : Juvenile myelomonocytic leukemia (JMML) is a lethal myeloproliferative disease of young childhood characterized clinically by overproduction of myelomonocytic cells and by the in vitro phenotype of hematopoietic progenitor hypersensitivity to granulocyte-macrophage colony-stimulating factor.\nsynonyms :Juvenile myelomonocytic leukaemia\n'}


{'id': 'HP_0012210', 'url': 'http://purl.obolibrary.org/obo/HP_0012210', 'lbl': 'Abnormal renal morphology', 'desc': 'label: Abnormal renal morphology\ndefinition : Any structural anomaly of the kidney.\nsynonyms :Abnormal kidney morphology; Abnormally shaped kidney; Kidney malformation; Kidney structure issue; Renal malformation; Structural anomalies of the renal tract; Structural kidney abnormalities; Structural renal anomalies\n'}


{'id': 'HP_0012211', 'url': 'http://purl.obolibrary.org/obo/HP_0012211', 'lbl': 'Abnormal renal physiology', 'desc': 'label: Abnormal renal physiology\ndefinition : An abnormal functionality of the kidney.\nsynonyms :Abnormal kidney function; Abnormal renal function; Abnormality of renal physiology; Kidney function issue; Renal functional abnormality\n'}


{'id': 'HP_0012212', 'url': 'http://purl.obolibrary.org/obo/HP_0012212', 'lbl': 'Abnormal glomerular filtration rate', 'desc': "label: Abnormal glomerular filtration rate\ndefinition : An abnormally increased or reduced amount of fluid filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time.\nsynonyms :Abnormal GFR\n"}


{'id': 'HP_0012213', 'url': 'http://purl.obolibrary.org/obo/HP_0012213', 'lbl': 'Decreased glomerular filtration rate', 'desc': "label: Decreased glomerular filtration rate\ndefinition : An abnormal reduction in the volume of fluid filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time.\nsynonyms :Decreased GFR; Impaired renal creatinine clearance; Reduced creatinine clearance\n"}


{'id': 'HP_0012214', 'url': 'http://purl.obolibrary.org/obo/HP_0012214', 'lbl': 'Increased glomerular filtration rate', 'desc': "label: Increased glomerular filtration rate\ndefinition : An abnormal rise in the volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time.\nsynonyms :Increased GFR\n"}


{'id': 'HP_0012215', 'url': 'http://purl.obolibrary.org/obo/HP_0012215', 'lbl': 'Testicular microlithiasis', 'desc': 'label: Testicular microlithiasis\ndefinition : The deposition of calcium phosphate microliths within the seminiferous tubules.\nsynonyms :\n'}


{'id': 'HP_0012216', 'url': 'http://purl.obolibrary.org/obo/HP_0012216', 'lbl': 'Entrapment neuropathy of suprascapular nerve', 'desc': 'label: Entrapment neuropathy of suprascapular nerve\ndefinition : An entrapment neuropathy of the suprascapular nerve, presenting with shoulder weakness confined to the supraspinatus muscle (this muscle initiates shoulder abduction) or to the infraspinatus (this muscle externally rotates the arm), as well as with pain in the posterior part of the shoulder and upper periscapular region.\nsynonyms :Suprascapular nerve entrapment\n'}


{'id': 'HP_0012217', 'url': 'http://purl.obolibrary.org/obo/HP_0012217', 'lbl': 'Increased urinary porphobilinogen', 'desc': 'label: Increased urinary porphobilinogen\ndefinition : Increased concentration of porphobilinogen in the urine.\nsynonyms :\n'}


{'id': 'HP_0012218', 'url': 'http://purl.obolibrary.org/obo/HP_0012218', 'lbl': 'Alveolar soft part sarcoma', 'desc': 'label: Alveolar soft part sarcoma\ndefinition : A type of soft tissue sarcoma with a histological appearance reminiscent of alveoli because of its reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue.\nsynonyms :\n'}


{'id': 'HP_0012219', 'url': 'http://purl.obolibrary.org/obo/HP_0012219', 'lbl': 'Erythema nodosum', 'desc': 'label: Erythema nodosum\ndefinition : An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral.\nsynonyms :\n'}


{'id': 'HP_0012220', 'url': 'http://purl.obolibrary.org/obo/HP_0012220', 'lbl': 'Non-caseating epithelioid cell granulomatosis', 'desc': 'label: Non-caseating epithelioid cell granulomatosis\ndefinition : The presence of multiple epithelioid cell granulomas consist of highly differentiated mononuclear phagocytes (epithelioid cells and giant cells) and lymphocytes, not exhibiting caseation (a form of necrosis in which the tissue changes into a dry, amorphous mass said to resemble cheese).\nsynonyms :\n'}


{'id': 'HP_0012221', 'url': 'http://purl.obolibrary.org/obo/HP_0012221', 'lbl': 'Pretibial blistering', 'desc': 'label: Pretibial blistering\ndefinition : A type of blistering that affects the skin of the tibial region.\nsynonyms :Pretibial epidermolysis bullosa\n'}


{'id': 'HP_0012222', 'url': 'http://purl.obolibrary.org/obo/HP_0012222', 'lbl': 'Arachnoid hemangiomatosis', 'desc': 'label: Arachnoid hemangiomatosis\ndefinition : The presence of multiple hemangiomas in the arachnoid.\nsynonyms :\n'}


{'id': 'HP_0012223', 'url': 'http://purl.obolibrary.org/obo/HP_0012223', 'lbl': 'Splenic rupture', 'desc': 'label: Splenic rupture\ndefinition : A breach of the capsule of the spleen.\nsynonyms :Ruptured spleen; Splenic rupture\n'}


{'id': 'HP_0012224', 'url': 'http://purl.obolibrary.org/obo/HP_0012224', 'lbl': 'Circulating immune complexes', 'desc': 'label: Circulating immune complexes\ndefinition : Persistence of immune complexes in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0012225', 'url': 'http://purl.obolibrary.org/obo/HP_0012225', 'lbl': 'Oligodontia of primary teeth', 'desc': 'label: Oligodontia of primary teeth\ndefinition : Reduced number of primary teeth.\nsynonyms :Failure of development of some deciduous teeth; Failure of development of some primary teeth; Partial anodontia of deciduous teeth; Partial anodontia of primary teeth; Decreased number of baby teeth; Decreased number of deciduous teeth; Decreased number of milk teeth; Decreased number of primary teeth; Fewer baby teeth than normal; Fewer deciduous teeth than normal; Fewer primary teeth than normal; Missing some baby teeth; Missing some milk teeth; Missing some primary teeth\n'}


{'id': 'HP_0012226', 'url': 'http://purl.obolibrary.org/obo/HP_0012226', 'lbl': 'Ovarian teratoma', 'desc': 'label: Ovarian teratoma\ndefinition : The presence of a teratoma in the ovary.\nsynonyms :\n'}


{'id': 'HP_0012227', 'url': 'http://purl.obolibrary.org/obo/HP_0012227', 'lbl': 'Urethral stricture', 'desc': 'label: Urethral stricture\ndefinition : Narrowing of the urethra associated with inflammation or scar tissue.\nsynonyms :\n'}


{'id': 'HP_0012228', 'url': 'http://purl.obolibrary.org/obo/HP_0012228', 'lbl': 'Tension-type headache', 'desc': 'label: Tension-type headache\ndefinition : A type of headache that last hours with continuous pain of mild or moderate intensity, bilateral location, a pressing/tightening (non-pulsating) quality and that is not aggravated by routine physical activity such as walking or climbing stairs.\nsynonyms :Tension-type headache\n'}


{'id': 'HP_0012229', 'url': 'http://purl.obolibrary.org/obo/HP_0012229', 'lbl': 'CSF pleocytosis', 'desc': 'label: CSF pleocytosis\ndefinition : An increased white blood cell count in the cerebrospinal fluid.\nsynonyms :Cerebrospinal fluid pleocytosis; Increased leukocyte count in CSF\n'}


{'id': 'HP_0012230', 'url': 'http://purl.obolibrary.org/obo/HP_0012230', 'lbl': 'Rhegmatogenous retinal detachment', 'desc': 'label: Rhegmatogenous retinal detachment\ndefinition : A type of retinal detachment associated with a retinal tear, that is, with a break in the retina that allows fluid to pass from the vitreous space into the subretinal space between the sensory retina and the retinal pigment epithelium.\nsynonyms :\n'}


{'id': 'HP_0012231', 'url': 'http://purl.obolibrary.org/obo/HP_0012231', 'lbl': 'Exudative retinal detachment', 'desc': 'label: Exudative retinal detachment\ndefinition : A type of retinal detachment arising from damage to the outer blood-retinal barrier that allows fluid to access the subretinal space and separate the neurosensory retina from the retinal pigment epithelium.\nsynonyms :Serous retinal detachment\n'}


{'id': 'HP_0012232', 'url': 'http://purl.obolibrary.org/obo/HP_0012232', 'lbl': 'Shortened QT interval', 'desc': 'label: Shortened QT interval\ndefinition : Decreased time between the start of the Q wave and the end of the T wave as measured by the electrocardiogram (EKG).\nsynonyms :\n'}


{'id': 'HP_0012233', 'url': 'http://purl.obolibrary.org/obo/HP_0012233', 'lbl': 'Intramuscular hematoma', 'desc': 'label: Intramuscular hematoma\ndefinition : Blood clot formed within muscle tissue following leakage of blood into the tissue.\nsynonyms :IM hematoma; Intramuscular haematoma; Intramuscular haemorrhage; Intramuscular hemorrhage; Intramuscular hematomas\n'}


{'id': 'HP_0012234', 'url': 'http://purl.obolibrary.org/obo/HP_0012234', 'lbl': 'Agranulocytosis', 'desc': 'label: Agranulocytosis\ndefinition : Marked decrease in the number of granulocytes.\nsynonyms :\n'}


{'id': 'HP_0012235', 'url': 'http://purl.obolibrary.org/obo/HP_0012235', 'lbl': 'Drug-induced agranulocytosis', 'desc': 'label: Drug-induced agranulocytosis\ndefinition : A type of agranulocytosis related to ingestion of a specific medication.\nsynonyms :\n'}


{'id': 'HP_0012236', 'url': 'http://purl.obolibrary.org/obo/HP_0012236', 'lbl': 'Elevated sweat chloride', 'desc': 'label: Elevated sweat chloride\ndefinition : An increased concentration of chloride in the sweat.\nsynonyms :Elevated sweat Cl; Elevated sweat Cl-; Elevated sweat chloride\n'}


{'id': 'HP_0012237', 'url': 'http://purl.obolibrary.org/obo/HP_0012237', 'lbl': 'Urocanic aciduria', 'desc': 'label: Urocanic aciduria\ndefinition : An increased concentration of urocanic acid in the urine.\nsynonyms :High urine urocanic acid levels\n'}


{'id': 'HP_0012238', 'url': 'http://purl.obolibrary.org/obo/HP_0012238', 'lbl': 'Increased circulating chylomicron concentration', 'desc': 'label: Increased circulating chylomicron concentration\ndefinition : Increased plasma concentrations of chylomicrons, the large lipid droplet (up to 100 mm in diameter) of reprocessed lipid synthesized in epithelial cells of the small intestine and containing triacylglycerols, cholesterol esters, and several apolipoproteins.\nsynonyms :Hyperchylomicronemia; Increased chylomicrons; Increased circulating chylomicron levels\n'}


{'id': 'HP_0012239', 'url': 'http://purl.obolibrary.org/obo/HP_0012239', 'lbl': 'Atransferrinemia', 'desc': 'label: Atransferrinemia\ndefinition : Absence of transferrin, a protein that transports iron, in the blood.\nsynonyms :\n'}


{'id': 'HP_0012240', 'url': 'http://purl.obolibrary.org/obo/HP_0012240', 'lbl': 'Increased intramyocellular lipid droplets', 'desc': 'label: Increased intramyocellular lipid droplets\ndefinition : An abnormal increase in intracellular lipid droplets In a muscle. The number and size of these drops can increase with somd disorders of lipid metabolism affecting muscle. See PMID 20691590 for histological images.\nsynonyms :Increased muscle lipid droplets\n'}


{'id': 'HP_0012241', 'url': 'http://purl.obolibrary.org/obo/HP_0012241', 'lbl': 'Levator palpebrae superioris atrophy', 'desc': 'label: Levator palpebrae superioris atrophy\ndefinition : Atrophy of the levator palpebrae superioris, the extraocular muscle that elevates the superior eyelid.\nsynonyms :\n'}


{'id': 'HP_0012242', 'url': 'http://purl.obolibrary.org/obo/HP_0012242', 'lbl': 'Superior rectus atrophy', 'desc': 'label: Superior rectus atrophy\ndefinition : Atrophy of the superior rectus, the extraocular muscle whose primary function is to elevate the globe.\nsynonyms :Rectus superior atrophy\n'}


{'id': 'HP_0012243', 'url': 'http://purl.obolibrary.org/obo/HP_0012243', 'lbl': 'Abnormal reproductive system morphology', 'desc': 'label: Abnormal reproductive system morphology\ndefinition : A structural or developmental anomaly of any of the tissues involved in the genital system.\nsynonyms :Abnormal genital system morphology\n'}


{'id': 'HP_0012244', 'url': 'http://purl.obolibrary.org/obo/HP_0012244', 'lbl': 'Abnormal sex determination', 'desc': 'label: Abnormal sex determination\ndefinition : Anomaly of primary or secondary sexual development or characteristics.\nsynonyms :\n'}


{'id': 'HP_0012245', 'url': 'http://purl.obolibrary.org/obo/HP_0012245', 'lbl': 'Sex reversal', 'desc': 'label: Sex reversal\ndefinition : Development of the reproductive system is inconsistent with the chromosomal sex.\nsynonyms :\n'}


{'id': 'HP_0012246', 'url': 'http://purl.obolibrary.org/obo/HP_0012246', 'lbl': 'Oculomotor nerve palsy', 'desc': 'label: Oculomotor nerve palsy\ndefinition : Reduced ability to control the movement of the eye associated with damage to the third cranial nerve (the oculomotor nerve).\nsynonyms :Oculomotor neuropathy\n'}


{'id': 'HP_0012247', 'url': 'http://purl.obolibrary.org/obo/HP_0012247', 'lbl': 'Specific anosmia', 'desc': 'label: Specific anosmia\ndefinition : Anosmia for one particular odor.\nsynonyms :\n'}


{'id': 'HP_0012248', 'url': 'http://purl.obolibrary.org/obo/HP_0012248', 'lbl': 'Prolonged PR interval', 'desc': 'label: Prolonged PR interval\ndefinition : Increased time for the PR interval (beginning of the P wave to the beginning of the QRS complex).\nsynonyms :Electrocardiographic long PR interval; Lengthened PR interval on EKG\n'}


{'id': 'HP_0012249', 'url': 'http://purl.obolibrary.org/obo/HP_0012249', 'lbl': 'Abnormal ST segment', 'desc': 'label: Abnormal ST segment\ndefinition : An electrocardiographic anomaly of the ST segment, which is the segment that connects the QRS complex and the T wave. The ST segment normally has a duration of 80 to 120 ms, is flat and at the same level (isoelectric) as the PR and TP segment.\nsynonyms :\n'}


{'id': 'HP_0012250', 'url': 'http://purl.obolibrary.org/obo/HP_0012250', 'lbl': 'ST segment depression', 'desc': 'label: ST segment depression\ndefinition : An electrocardiographic anomaly in which the ST segment is observed to be located inferior to the isoelectric line.\nsynonyms :\n'}


{'id': 'HP_0012251', 'url': 'http://purl.obolibrary.org/obo/HP_0012251', 'lbl': 'ST segment elevation', 'desc': 'label: ST segment elevation\ndefinition : An electrocardiographic anomaly in which the ST segment is observed to be located superior to the isoelectric line.\nsynonyms :\n'}


{'id': 'HP_0012252', 'url': 'http://purl.obolibrary.org/obo/HP_0012252', 'lbl': 'Abnormal respiratory system morphology', 'desc': 'label: Abnormal respiratory system morphology\ndefinition : A structural anomaly of the respiratory system.\nsynonyms :\n'}


{'id': 'HP_0012253', 'url': 'http://purl.obolibrary.org/obo/HP_0012253', 'lbl': 'Abnormal respiratory epithelium morphology', 'desc': 'label: Abnormal respiratory epithelium morphology\ndefinition : Any structural anomaly of the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi.\nsynonyms :\n'}


{'id': 'HP_0012254', 'url': 'http://purl.obolibrary.org/obo/HP_0012254', 'lbl': 'Ewing sarcoma', 'desc': "label: Ewing sarcoma\ndefinition : A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones.\nsynonyms :Ewing's sarcoma\n"}


{'id': 'HP_0012255', 'url': 'http://purl.obolibrary.org/obo/HP_0012255', 'lbl': 'Dynein arm defect of respiratory motile cilia', 'desc': 'label: Dynein arm defect of respiratory motile cilia\ndefinition : An anomaly of the dynein arms of motile cilia. This feature is usually appreciated by electron microscopy.\nsynonyms :\n'}


{'id': 'HP_0012256', 'url': 'http://purl.obolibrary.org/obo/HP_0012256', 'lbl': 'Absent outer dynein arms', 'desc': 'label: Absent outer dynein arms\ndefinition : Absence of the outer dynein arms of respiratory motile cilia, which normally are situated outside of the peripheral microtubules of motile cilia. This feature is usually appreciated by electron microscopy.\nsynonyms :\n'}


{'id': 'HP_0012257', 'url': 'http://purl.obolibrary.org/obo/HP_0012257', 'lbl': 'Absent inner dynein arms', 'desc': 'label: Absent inner dynein arms\ndefinition : Absence of the inner dynein arms of respiratory motile cilia, which normally are situated within the peripheral microtubules of motile cilia. This feature is usually appreciated by electron microscopy.\nsynonyms :\n'}


{'id': 'HP_0012258', 'url': 'http://purl.obolibrary.org/obo/HP_0012258', 'lbl': 'Abnormal axonemal organization of respiratory motile cilia', 'desc': 'label: Abnormal axonemal organization of respiratory motile cilia\ndefinition : Abnormal arrangement of the structures of the axoneme, which is the cytoskeletal structure that forms the inner core of the motile cilium and displays a canonical 9+2 microtubular pattern of motile cilia studded with dynein arms.\nsynonyms :Abnormal axonemal organisation of respiratory motile cilia\n'}


{'id': 'HP_0012259', 'url': 'http://purl.obolibrary.org/obo/HP_0012259', 'lbl': 'Absent inner and outer dynein arms', 'desc': 'label: Absent inner and outer dynein arms\ndefinition : Complete absence of the dynein arms of respiratory motile cilia, that is, absence of the inner and the outer dynein arms, which normally are situated inside and outside of the peripheral microtubules of motile cilia. This feature is usually appreciated by electron microscopy.\nsynonyms :\n'}


{'id': 'HP_0012260', 'url': 'http://purl.obolibrary.org/obo/HP_0012260', 'lbl': 'Abnormal central microtubular pair morphology of respiratory motile cilia', 'desc': 'label: Abnormal central microtubular pair morphology of respiratory motile cilia\ndefinition : A structural anomaly of the two central microtubules of motile cilia with a 9+2 microtubuluar configuration.\nsynonyms :\n'}


{'id': 'HP_0012261', 'url': 'http://purl.obolibrary.org/obo/HP_0012261', 'lbl': 'Abnormal respiratory motile cilium physiology', 'desc': 'label: Abnormal respiratory motile cilium physiology\ndefinition : Any functional anomaly of the respiratory motile cilia.\nsynonyms :\n'}


{'id': 'HP_0012262', 'url': 'http://purl.obolibrary.org/obo/HP_0012262', 'lbl': 'Abnormal ciliary motility', 'desc': 'label: Abnormal ciliary motility\ndefinition : Any anomaly of the normal motility of motile cilia. Evaluation of ciliary beat frequency and ciliary beat pattern requires high-speed videomicroscopy of freshly obtained ciliary biopsies that are maintained in culture media under controlled conditions.\nsynonyms :\n'}


{'id': 'HP_0012263', 'url': 'http://purl.obolibrary.org/obo/HP_0012263', 'lbl': 'Immotile cilia', 'desc': 'label: Immotile cilia\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012264', 'url': 'http://purl.obolibrary.org/obo/HP_0012264', 'lbl': 'Absent central microtubular pair morphology of respiratory motile cilia', 'desc': 'label: Absent central microtubular pair morphology of respiratory motile cilia\ndefinition : Absence of the two central microtubules of motile cilia with a 9+2 microtubuluar configuration.\nsynonyms :\n'}


{'id': 'HP_0012265', 'url': 'http://purl.obolibrary.org/obo/HP_0012265', 'lbl': 'Ciliary dyskinesia', 'desc': 'label: Ciliary dyskinesia\ndefinition : A deviation from the normally well coordinated pattern of intracellular and intercellular synchrony of motile cilia. Dyskinetic cilia usually beat out of synchrony relative to neighboring cilia.\nsynonyms :Lack of coordinated beating of respiratory cilia\n'}


{'id': 'HP_0012266', 'url': 'http://purl.obolibrary.org/obo/HP_0012266', 'lbl': 'T-wave alternans', 'desc': 'label: T-wave alternans\ndefinition : A periodic beat-to-beat variation in the amplitude or shape of the T wave in an EKG.\nsynonyms :\n'}


{'id': 'HP_0012267', 'url': 'http://purl.obolibrary.org/obo/HP_0012267', 'lbl': 'Absent respiratory ciliary axoneme radial spokes', 'desc': 'label: Absent respiratory ciliary axoneme radial spokes\ndefinition : Absence of the radial spokes of the axoneme of the respiratory cilium.\nsynonyms :\n'}


{'id': 'HP_0012268', 'url': 'http://purl.obolibrary.org/obo/HP_0012268', 'lbl': 'Myxoid liposarcoma', 'desc': 'label: Myxoid liposarcoma\ndefinition : A liposarcoma that contains myxomatous tissue.\nsynonyms :\n'}


{'id': 'HP_0012269', 'url': 'http://purl.obolibrary.org/obo/HP_0012269', 'lbl': 'Abnormal muscle glycogen content', 'desc': 'label: Abnormal muscle glycogen content\ndefinition : Any anomaly in the amount of glycogen in muscle tissue.\nsynonyms :\n'}


{'id': 'HP_0012270', 'url': 'http://purl.obolibrary.org/obo/HP_0012270', 'lbl': 'Decreased muscle glycogen content', 'desc': 'label: Decreased muscle glycogen content\ndefinition : A decreased amount of glycogen in muscle tissue.\nsynonyms :\n'}


{'id': 'HP_0012271', 'url': 'http://purl.obolibrary.org/obo/HP_0012271', 'lbl': 'Episodic upper airway obstruction', 'desc': 'label: Episodic upper airway obstruction\ndefinition : Intermittent episodes of increased resistance to the passage of air in the upper airway.\nsynonyms :\n'}


{'id': 'HP_0012272', 'url': 'http://purl.obolibrary.org/obo/HP_0012272', 'lbl': 'J wave', 'desc': 'label: J wave\ndefinition : The J wave is a positive convex deflection that occurs at the junction of the QRS complex and ST segment, the J-point.\nsynonyms :EKG J waves; Osborne waves\n'}


{'id': 'HP_0012273', 'url': 'http://purl.obolibrary.org/obo/HP_0012273', 'lbl': 'Increased carotid artery intimal medial thickness', 'desc': 'label: Increased carotid artery intimal medial thickness\ndefinition : An increase in the combined thickness of the intima and media of the carotid artery.\nsynonyms :\n'}


{'id': 'HP_0012274', 'url': 'http://purl.obolibrary.org/obo/HP_0012274', 'lbl': 'Autosomal dominant inheritance with paternal imprinting', 'desc': 'label: Autosomal dominant inheritance with paternal imprinting\ndefinition : A type of autosomal dominant inheritance involving a gene that is imprinted with paternal silencing.\nsynonyms :\n'}


{'id': 'HP_0012275', 'url': 'http://purl.obolibrary.org/obo/HP_0012275', 'lbl': 'Autosomal dominant inheritance with maternal imprinting', 'desc': 'label: Autosomal dominant inheritance with maternal imprinting\ndefinition : A type of autosomal dominant inheritance involving a gene that is imprinted with maternal silencing.\nsynonyms :\n'}


{'id': 'HP_0012276', 'url': 'http://purl.obolibrary.org/obo/HP_0012276', 'lbl': 'Digital flexor tenosynovitis', 'desc': 'label: Digital flexor tenosynovitis\ndefinition : Inflammation of the flexor digitorum tendon, often associated with the Kanavel signs: (i) finger held in slight flexion, (ii) fusiform swelling, (iii) tenderness along the flexor tendon sheath, and (iv) pain with passive extension of the digit.\nsynonyms :Trigger finger\n'}


{'id': 'HP_0012277', 'url': 'http://purl.obolibrary.org/obo/HP_0012277', 'lbl': 'Hypoglycinemia', 'desc': 'label: Hypoglycinemia\ndefinition : An abnormally reduced concentration of glycine in the blood.\nsynonyms :Low blood glycine levels\n'}


{'id': 'HP_0012278', 'url': 'http://purl.obolibrary.org/obo/HP_0012278', 'lbl': 'Abnormal circulating serine concentration', 'desc': 'label: Abnormal circulating serine concentration\ndefinition : Any deviation from the normal concentration of serine in the blood circulation.\nsynonyms :\n'}


{'id': 'HP_0012279', 'url': 'http://purl.obolibrary.org/obo/HP_0012279', 'lbl': 'Hyposerinemia', 'desc': 'label: Hyposerinemia\ndefinition : Reduced concentration of serine in the blood.\nsynonyms :Low blood serine levels\n'}


{'id': 'HP_0012280', 'url': 'http://purl.obolibrary.org/obo/HP_0012280', 'lbl': 'Hepatic amyloidosis', 'desc': 'label: Hepatic amyloidosis\ndefinition : A form of amyloidosis that affects the liver.\nsynonyms :\n'}


{'id': 'HP_0012281', 'url': 'http://purl.obolibrary.org/obo/HP_0012281', 'lbl': 'Chylous ascites', 'desc': 'label: Chylous ascites\ndefinition : Extravasation of chyle into the peritoneal cavity.\nsynonyms :Chyloperitoneum\n'}


{'id': 'HP_0012282', 'url': 'http://purl.obolibrary.org/obo/HP_0012282', 'lbl': 'Morbilliform rash', 'desc': 'label: Morbilliform rash\ndefinition : An exanthema consisting of widespread pink-to-red macules (flat spots of 2-10 mm in diameter) or papules (red bumps) that blanch with pressure. The macules and papules may cluster and merge to form sheets over several days.\nsynonyms :\n'}


{'id': 'HP_0012283', 'url': 'http://purl.obolibrary.org/obo/HP_0012283', 'lbl': 'Small distal femoral epiphysis', 'desc': 'label: Small distal femoral epiphysis\ndefinition : Reduced size of the Distal epiphysis of femur.\nsynonyms :Small end part of outermost thighbone\n'}


{'id': 'HP_0012284', 'url': 'http://purl.obolibrary.org/obo/HP_0012284', 'lbl': 'Small proximal tibial epiphyses', 'desc': 'label: Small proximal tibial epiphyses\ndefinition : Reduced size of the proximal epiphysis of the tibia.\nsynonyms :Small end part of innermost shankbone; Small end part of innermost shinbone\n'}


{'id': 'HP_0012285', 'url': 'http://purl.obolibrary.org/obo/HP_0012285', 'lbl': 'Abnormal hypothalamus physiology', 'desc': 'label: Abnormal hypothalamus physiology\ndefinition : An abnormal functionality of the hypothalamus.\nsynonyms :\n'}


{'id': 'HP_0012286', 'url': 'http://purl.obolibrary.org/obo/HP_0012286', 'lbl': 'Abnormal hypothalamus morphology', 'desc': 'label: Abnormal hypothalamus morphology\ndefinition : Any structural anomaly of the hypothalamus.\nsynonyms :Abnormal shape of hypothalamus; Abnormality of hypothalamus morphology; Abnormality of the hypothalamus\n'}


{'id': 'HP_0012287', 'url': 'http://purl.obolibrary.org/obo/HP_0012287', 'lbl': 'Hypothalamic luteinizing hormone-releasing hormone deficiency', 'desc': 'label: Hypothalamic luteinizing hormone-releasing hormone deficiency\ndefinition : Decreased secretion of luteinizing hormone-releasing hormone by the hypothalamus.\nsynonyms :\n'}


{'id': 'HP_0012288', 'url': 'http://purl.obolibrary.org/obo/HP_0012288', 'lbl': 'Neoplasm of head and neck', 'desc': 'label: Neoplasm of head and neck\ndefinition : A tumor (abnormal growth of tissue) of the head and neck region with origin in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, or larynx.\nsynonyms :Head and neck tumor; Head and neck tumour; Head and neck cancer\n'}


{'id': 'HP_0012289', 'url': 'http://purl.obolibrary.org/obo/HP_0012289', 'lbl': 'Facial neoplasm', 'desc': 'label: Facial neoplasm\ndefinition : A tumor (abnormal growth of tissue) of the face.\nsynonyms :Face tumor; Face tumour\n'}


{'id': 'HP_0012290', 'url': 'http://purl.obolibrary.org/obo/HP_0012290', 'lbl': 'obsolete Mouth neoplasm', 'desc': 'label: obsolete Mouth neoplasm\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012291', 'url': 'http://purl.obolibrary.org/obo/HP_0012291', 'lbl': 'obsolete Tracheal neoplasm', 'desc': 'label: obsolete Tracheal neoplasm\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012292', 'url': 'http://purl.obolibrary.org/obo/HP_0012292', 'lbl': 'Fusion of gums', 'desc': 'label: Fusion of gums\ndefinition : A congenital defect with an abnormal joining of the gums of the upper and lower jaw.\nsynonyms :Fusion of gums; Fusion of the gingiva; Gingival synechia; Partial fusion of the gums; Synechia of the gums; Upper and lower gums fused together\n'}


{'id': 'HP_0012293', 'url': 'http://purl.obolibrary.org/obo/HP_0012293', 'lbl': 'Abnormal genital pigmentation', 'desc': 'label: Abnormal genital pigmentation\ndefinition : An abnormal pigmentation pattern of the external genitalia.\nsynonyms :\n'}


{'id': 'HP_0012294', 'url': 'http://purl.obolibrary.org/obo/HP_0012294', 'lbl': 'Abnormal occipital bone morphology', 'desc': 'label: Abnormal occipital bone morphology\ndefinition : Abnormality of the occipital bone of the skull.\nsynonyms :Abnormality of the occipital bone\n'}


{'id': 'HP_0012295', 'url': 'http://purl.obolibrary.org/obo/HP_0012295', 'lbl': 'Slender middle phalanx of finger', 'desc': 'label: Slender middle phalanx of finger\ndefinition : Reduced diameter of the middle phalanx of finger.\nsynonyms :Slender middle bone of finger\n'}


{'id': 'HP_0012296', 'url': 'http://purl.obolibrary.org/obo/HP_0012296', 'lbl': 'Slender distal phalanx of finger', 'desc': 'label: Slender distal phalanx of finger\ndefinition : Reduced diameter of the distal phalanx of finger.\nsynonyms :Slender outermost bone of finger\n'}


{'id': 'HP_0012297', 'url': 'http://purl.obolibrary.org/obo/HP_0012297', 'lbl': 'Slender proximal phalanx of finger', 'desc': 'label: Slender proximal phalanx of finger\ndefinition : Reduced diameter of the proximal phalanx of finger.\nsynonyms :Slender innermost bone of finger\n'}


{'id': 'HP_0012298', 'url': 'http://purl.obolibrary.org/obo/HP_0012298', 'lbl': 'Long middle phalanx of finger', 'desc': 'label: Long middle phalanx of finger\ndefinition : Increased length of the middle phalanx of finger.\nsynonyms :Long middle bone of finger\n'}


{'id': 'HP_0012299', 'url': 'http://purl.obolibrary.org/obo/HP_0012299', 'lbl': 'Long distal phalanx of finger', 'desc': 'label: Long distal phalanx of finger\ndefinition : Increased length of the distal phalanx of finger.\nsynonyms :Long outermost bone of finger\n'}


{'id': 'HP_0012300', 'url': 'http://purl.obolibrary.org/obo/HP_0012300', 'lbl': 'Ureteral agenesis', 'desc': 'label: Ureteral agenesis\ndefinition : Failure of the ureter to undergo development.\nsynonyms :\n'}


{'id': 'HP_0012301', 'url': 'http://purl.obolibrary.org/obo/HP_0012301', 'lbl': 'Type II transferrin isoform profile', 'desc': 'label: Type II transferrin isoform profile\ndefinition : Abnormal transferrin isoform profile consistent with a type II congenital disorder of glycosylation.\nsynonyms :Abnormal isoelectric focusing of serum transferrin, type II pattern; Isoelectric focusing of serum transferrin consistent with CDG type II; Type 2 transferrin isoform profile; Abnormal isoelectric focusing of serum transferrin, type 2 pattern\n'}


{'id': 'HP_0012302', 'url': 'http://purl.obolibrary.org/obo/HP_0012302', 'lbl': 'Herpes simplex encephalitis', 'desc': 'label: Herpes simplex encephalitis\ndefinition : Infection of the brain parenchyma with herpes simplex virus, resulting in inflammation of the brain parenchyma with neurologic dysfunction.\nsynonyms :Herpes encephalitis\n'}


{'id': 'HP_0012303', 'url': 'http://purl.obolibrary.org/obo/HP_0012303', 'lbl': 'Abnormal aortic arch morphology', 'desc': 'label: Abnormal aortic arch morphology\ndefinition : An anomaly of the arch of aorta.\nsynonyms :Abnormality of the aortic arch\n'}


{'id': 'HP_0012304', 'url': 'http://purl.obolibrary.org/obo/HP_0012304', 'lbl': 'Hypoplastic aortic arch', 'desc': 'label: Hypoplastic aortic arch\ndefinition : Underdevelopment of the arch of aorta.\nsynonyms :Aortic arch hypoplasia; Underdeveloped aortic arch\n'}


{'id': 'HP_0012305', 'url': 'http://purl.obolibrary.org/obo/HP_0012305', 'lbl': 'Coarctation of the descending aortic arch', 'desc': 'label: Coarctation of the descending aortic arch\ndefinition : Narrowing or constriction of the aorta localized to the region of the descending trunk of arch of aorta.\nsynonyms :\n'}


{'id': 'HP_0012306', 'url': 'http://purl.obolibrary.org/obo/HP_0012306', 'lbl': 'Abnormal rib ossification', 'desc': 'label: Abnormal rib ossification\ndefinition : An anomaly of the process of rib bone formation.\nsynonyms :Abnormal maturation of rib bones\n'}


{'id': 'HP_0012307', 'url': 'http://purl.obolibrary.org/obo/HP_0012307', 'lbl': 'Spatulate ribs', 'desc': 'label: Spatulate ribs\ndefinition : Ribs that are increased in width and taper to the posterior ends.\nsynonyms :\n'}


{'id': 'HP_0012308', 'url': 'http://purl.obolibrary.org/obo/HP_0012308', 'lbl': 'Decreased circulating complement C9 concentration', 'desc': 'label: Decreased circulating complement C9 concentration\ndefinition : Concentration of the complement component C9 in the blood circulation below the lower limit of normal.\nsynonyms :Decreased serum C9; Decreased serum complement C9\n'}


{'id': 'HP_0012309', 'url': 'http://purl.obolibrary.org/obo/HP_0012309', 'lbl': 'Cutaneous amyloidosis', 'desc': 'label: Cutaneous amyloidosis\ndefinition : The presence of amyloid deposition in the superficial dermis.\nsynonyms :\n'}


{'id': 'HP_0012310', 'url': 'http://purl.obolibrary.org/obo/HP_0012310', 'lbl': 'Abnormal monocyte count', 'desc': 'label: Abnormal monocyte count\ndefinition : An anomaly in the number of monocytes, which are myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.\nsynonyms :Abnormal monocyte number\n'}


{'id': 'HP_0012311', 'url': 'http://purl.obolibrary.org/obo/HP_0012311', 'lbl': 'Monocytosis', 'desc': 'label: Monocytosis\ndefinition : An increased number of circulating monocytes.\nsynonyms :High blood monocyte number\n'}


{'id': 'HP_0012312', 'url': 'http://purl.obolibrary.org/obo/HP_0012312', 'lbl': 'Monocytopenia', 'desc': 'label: Monocytopenia\ndefinition : An decreased number of circulating monocytes.\nsynonyms :Low blood monocyte number\n'}


{'id': 'HP_0012313', 'url': 'http://purl.obolibrary.org/obo/HP_0012313', 'lbl': "Heberden's node", 'desc': "label: Heberden's node\ndefinition : Bony swelling of the distal interphalangeal joint (DIP) associated with the formation of osteophytes (calcific spurs) of the articular (joint) cartilage that are visible radiographically.\nsynonyms :\n"}


{'id': 'HP_0012314', 'url': 'http://purl.obolibrary.org/obo/HP_0012314', 'lbl': "Bouchard's node", 'desc': "label: Bouchard's node\ndefinition : Bony swelling of the proximal interphalangeal joint (PIP) associated with the formation of osteophytes (calcific spurs) of the articular (joint) cartilage that are visible radiographically.\nsynonyms :\n"}


{'id': 'HP_0012315', 'url': 'http://purl.obolibrary.org/obo/HP_0012315', 'lbl': 'Histiocytoma', 'desc': 'label: Histiocytoma\ndefinition : A neoplasm containing histiocytes.\nsynonyms :\n'}


{'id': 'HP_0012316', 'url': 'http://purl.obolibrary.org/obo/HP_0012316', 'lbl': 'Fibrous tissue neoplasm', 'desc': 'label: Fibrous tissue neoplasm\ndefinition : Any neoplasm composed of fibrous tissue.\nsynonyms :\n'}


{'id': 'HP_0012317', 'url': 'http://purl.obolibrary.org/obo/HP_0012317', 'lbl': 'Sacroiliac arthritis', 'desc': 'label: Sacroiliac arthritis\ndefinition : Inflammation of the sacroiliac joint, generally accompanied by lower back pain.\nsynonyms :Sacroiliitis\n'}


{'id': 'HP_0012318', 'url': 'http://purl.obolibrary.org/obo/HP_0012318', 'lbl': 'Occipital neuralgia', 'desc': 'label: Occipital neuralgia\ndefinition : A distinct type of headache characterized by piercing, throbbing, or electric-shock-like chronic pain in the upper neck, back of the head, and behind the ears, usually on one side.\nsynonyms :\n'}


{'id': 'HP_0012319', 'url': 'http://purl.obolibrary.org/obo/HP_0012319', 'lbl': 'Absent pigmentation of the abdomen', 'desc': 'label: Absent pigmentation of the abdomen\ndefinition : Lack of skin pigmentation (coloring) of the abdomen.\nsynonyms :\n'}


{'id': 'HP_0012320', 'url': 'http://purl.obolibrary.org/obo/HP_0012320', 'lbl': 'Absent pigmentation of the limbs', 'desc': 'label: Absent pigmentation of the limbs\ndefinition : Lack of skin pigmentation (coloring) of the arms and legs.\nsynonyms :\n'}


{'id': 'HP_0012321', 'url': 'http://purl.obolibrary.org/obo/HP_0012321', 'lbl': 'D-2-hydroxyglutaric aciduria', 'desc': 'label: D-2-hydroxyglutaric aciduria\ndefinition : An increased concentration of 2-hydroxyglutaric acid in the urine.\nsynonyms :\n'}


{'id': 'HP_0012322', 'url': 'http://purl.obolibrary.org/obo/HP_0012322', 'lbl': 'Perifolliculitis', 'desc': 'label: Perifolliculitis\ndefinition : Inflammation surrounding hair follicles.\nsynonyms :Perifollicular inflammation\n'}


{'id': 'HP_0012323', 'url': 'http://purl.obolibrary.org/obo/HP_0012323', 'lbl': 'Sleep myoclonus', 'desc': 'label: Sleep myoclonus\ndefinition : Myoclonus that occurs during the initial phases of sleep.\nsynonyms :\n'}


{'id': 'HP_0012324', 'url': 'http://purl.obolibrary.org/obo/HP_0012324', 'lbl': 'Myeloid leukemia', 'desc': 'label: Myeloid leukemia\ndefinition : A leukemia that originates from a myeloid cell, that is the blood forming cells of the bone marrow.\nsynonyms :Myeloid leukaemia\n'}


{'id': 'HP_0012325', 'url': 'http://purl.obolibrary.org/obo/HP_0012325', 'lbl': 'Chronic myelomonocytic leukemia', 'desc': 'label: Chronic myelomonocytic leukemia\ndefinition : A myelodysplastic/myeloproliferative neoplasm which is characterized by persistent monocytosis, absence of a Philadelphia chromosome and BCR/ABL fusion gene, fewer than 20 percent blasts in the bone marrow and blood, myelodysplasia, and absence of PDGFRA or PDGFRB rearrangement.\nsynonyms :Chronic myelomonocytic leukaemia\n'}


{'id': 'HP_0012326', 'url': 'http://purl.obolibrary.org/obo/HP_0012326', 'lbl': 'Abnormal celiac artery morphology', 'desc': 'label: Abnormal celiac artery morphology\ndefinition : An anomaly of the celiac artery.\nsynonyms :Abnormal coeliac artery morphology; Abnormality of the celiac artery; Abnormality of the coeliac artery\n'}


{'id': 'HP_0012327', 'url': 'http://purl.obolibrary.org/obo/HP_0012327', 'lbl': 'Celiac artery compression', 'desc': 'label: Celiac artery compression\ndefinition : Compression of the celiac artery.\nsynonyms :Coeliac artery compression; Celiac axis syndrome; Coeliac axis syndrome; Dunbar syndrome; Median arcuate ligament syndrome\n'}


{'id': 'HP_0012328', 'url': 'http://purl.obolibrary.org/obo/HP_0012328', 'lbl': 'Cementoma', 'desc': 'label: Cementoma\ndefinition : An odontogenic tumor of the cementum of tooth.\nsynonyms :\n'}


{'id': 'HP_0012329', 'url': 'http://purl.obolibrary.org/obo/HP_0012329', 'lbl': 'Tufted angioma', 'desc': 'label: Tufted angioma\ndefinition : A vascular tumor of the skin and subcutaneous tissues and characterized by slow angiomatous proliferation.\nsynonyms :Angioblastoma; Angioblastoma of Nakagawa; Hypertrophic hemangioma; Progressive capillary hemangioma; Tufted hemangioma\n'}


{'id': 'HP_0012330', 'url': 'http://purl.obolibrary.org/obo/HP_0012330', 'lbl': 'Pyelonephritis', 'desc': 'label: Pyelonephritis\ndefinition : An inflammation of the kidney involving the parenchyma of kidney, the renal pelvis and the kidney calices.\nsynonyms :\n'}


{'id': 'HP_0012331', 'url': 'http://purl.obolibrary.org/obo/HP_0012331', 'lbl': 'Abnormal autonomic nervous system morphology', 'desc': 'label: Abnormal autonomic nervous system morphology\ndefinition : A structural abnormality of the autonomic nervous system.\nsynonyms :\n'}


{'id': 'HP_0012332', 'url': 'http://purl.obolibrary.org/obo/HP_0012332', 'lbl': 'Abnormal autonomic nervous system physiology', 'desc': 'label: Abnormal autonomic nervous system physiology\ndefinition : A functional abnormality of the autonomic nervous system.\nsynonyms :Autonomic dysfunction; Autonomic dysregulation; Dysautonomia\n'}


{'id': 'HP_0012333', 'url': 'http://purl.obolibrary.org/obo/HP_0012333', 'lbl': 'Abnormal sudomotor regulation', 'desc': 'label: Abnormal sudomotor regulation\ndefinition : An abnormal regulation of the sweat glands by the sympathetic nervous system associated with abnormal perspiration.\nsynonyms :Sudomotor sympathetic dysfunction\n'}


{'id': 'HP_0012334', 'url': 'http://purl.obolibrary.org/obo/HP_0012334', 'lbl': 'Extrahepatic cholestasis', 'desc': 'label: Extrahepatic cholestasis\ndefinition : Impairment of bile flow due to obstruction in large bile ducts outside the liver.\nsynonyms :\n'}


{'id': 'HP_0012335', 'url': 'http://purl.obolibrary.org/obo/HP_0012335', 'lbl': 'Abnormality of folate metabolism', 'desc': 'label: Abnormality of folate metabolism\ndefinition : An abnormality of the metabolism of folic acid, which is also known as vitamin B9.\nsynonyms :\n'}


{'id': 'HP_0012336', 'url': 'http://purl.obolibrary.org/obo/HP_0012336', 'lbl': 'obsolete Reduced cerebrospinal fluid 5-methyltetrahydrofolate concentration', 'desc': 'label: obsolete Reduced cerebrospinal fluid 5-methyltetrahydrofolate concentration\ndefinition : \nsynonyms :\n'}


{'id': 'HP_0012337', 'url': 'http://purl.obolibrary.org/obo/HP_0012337', 'lbl': 'Abnormal homeostasis', 'desc': 'label: Abnormal homeostasis\ndefinition : An anomaly in the processes involved in the maintenance of an internal equilibrium.\nsynonyms :\n'}


{'id': 'HP_0012338', 'url': 'http://purl.obolibrary.org/obo/HP_0012338', 'lbl': 'Abnormal energy expenditure', 'desc': 'label: Abnormal energy expenditure\ndefinition : Any anomaly in the utilization of energy (calories).\nsynonyms :Abnormal energy expenditure\n'}


{'id': 'HP_0012339', 'url': 'http://purl.obolibrary.org/obo/HP_0012339', 'lbl': 'Increased resting energy expenditure', 'desc': 'label: Increased resting energy expenditure\ndefinition : An increase in the number of calories used per unit time.\nsynonyms :\n'}


{'id': 'HP_0012340', 'url': 'http://purl.obolibrary.org/obo/HP_0012340', 'lbl': 'Decreased resting energy expenditure', 'desc': 'label: Decreased resting energy expenditure\ndefinition : A reduction in the number of calories used per unit time.\nsynonyms :\n'}


{'id': 'HP_0012341', 'url': 'http://purl.obolibrary.org/obo/HP_0012341', 'lbl': 'Microprolactinoma', 'desc': 'label: Microprolactinoma\ndefinition : A pituitary prolactin cell adenoma of less than 10 mm diameter.\nsynonyms :\n'}


{'id': 'HP_0012342', 'url': 'http://purl.obolibrary.org/obo/HP_0012342', 'lbl': 'Macroprolactinoma', 'desc': 'label: Macroprolactinoma\ndefinition : A pituitary prolactin cell adenoma of more than 10 mm diameter.\nsynonyms :\n'}


{'id': 'HP_0012343', 'url': 'http://purl.obolibrary.org/obo/HP_0012343', 'lbl': 'Decreased circulating ferritin concentration', 'desc': 'label: Decreased circulating ferritin concentration\ndefinition : Abnormally reduced concentration of ferritin, a ubiquitous intracellular protein that stores iron, in the blood.\nsynonyms :Decreased plasma ferritin; Decreased serum ferritin; Low ferritin level; Reduced serum ferritin\n'}


{'id': 'HP_0012344', 'url': 'http://purl.obolibrary.org/obo/HP_0012344', 'lbl': 'Morphea', 'desc': 'label: Morphea\ndefinition : Isolated patches of hardened skin (scleroderma).\nsynonyms :\n'}


{'id': 'HP_0012345', 'url': 'http://purl.obolibrary.org/obo/HP_0012345', 'lbl': 'Abnormal glycosylation', 'desc': 'label: Abnormal glycosylation\ndefinition : An anomaly of a glycosylation process, i.e., a process involved in the covalent attachment of a glycosyl residue to a substrate molecule.\nsynonyms :\n'}


{'id': 'HP_0012346', 'url': 'http://purl.obolibrary.org/obo/HP_0012346', 'lbl': 'Abnormal protein glycosylation', 'desc': 'label: Abnormal protein glycosylation\ndefinition : An anomaly of a protein glycosylation process, i.e., of a protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.\nsynonyms :\n'}


{'id': 'HP_0012347', 'url': 'http://purl.obolibrary.org/obo/HP_0012347', 'lbl': 'Abnormal protein N-linked glycosylation', 'desc': 'label: Abnormal protein N-linked glycosylation\ndefinition : An anomaly of protein N-linked glycosylation, i.e., an abnormality of the protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a nitrogen atom in an amino acid residue in a protein.\nsynonyms :\n'}


{'id': 'HP_0012348', 'url': 'http://purl.obolibrary.org/obo/HP_0012348', 'lbl': 'Decreased galactosylation of N-linked protein glycosylation', 'desc': 'label: Decreased galactosylation of N-linked protein glycosylation\ndefinition : A reduction in the amount of galactose residues of N-glycans.\nsynonyms :\n'}


{'id': 'HP_0012349', 'url': 'http://purl.obolibrary.org/obo/HP_0012349', 'lbl': 'Abnormal sialylation of N-linked protein glycosylation', 'desc': 'label: Abnormal sialylation of N-linked protein glycosylation\ndefinition : An anomaly of the addition of sialic acids to N-linked glycans.\nsynonyms :\n'}


{'id': 'HP_0012350', 'url': 'http://purl.obolibrary.org/obo/HP_0012350', 'lbl': 'Decreased sialylation of N-linked protein glycosylation', 'desc': 'label: Decreased sialylation of N-linked protein glycosylation\ndefinition : Decreased addition of sialic acids to N-linked glycans.\nsynonyms :\n'}


{'id': 'HP_0012351', 'url': 'http://purl.obolibrary.org/obo/HP_0012351', 'lbl': 'Increased sialylation of N-linked protein glycosylation', 'desc': 'label: Increased sialylation of N-linked protein glycosylation\ndefinition : Increased addition of sialic acids to N-linked glycans.\nsynonyms :\n'}