# af_backprop various modifications to alphafold to allow backprop through the model ### projects that use af_backprop - [SMURF](https://github.com/spetti/SMURF): End-to-end learning of multiple sequence alignments with differentiable Smith-Waterman - [ColabDesign](https://github.com/sokrypton/ColabDesign): Making Protein Design accessible to all via Google Colab!