2013 Economics Nobel prize winner Robert J. Shiller said that rising inequality in the United States and elsewhere is the most important problem. Increasing inequality harms economic growth. High and persistent unemployment, in which inequality increases, has a negative effect on subsequent long-run economic growth. Unemployment can harm growth not only because it is a waste of resources, but also because it generates redistributive pressures and subsequent distortions, drives people to poverty, constrains liquidity limiting labor mobility, and erodes self-esteem promoting social dislocation, unrest and conflict. Policies aiming at controlling unemployment and in particular at reducing its inequality-associated effects support economic growth. A deterministic Turing machine is the most basic Turing machine, which uses a fixed set of rules to determine its future actions. A probabilistic Turing machine is a deterministic Turing machine with an extra supply of random bits. The ability to make probabilistic decisions often helps algorithms solve problems more efficiently. Algorithms that use random bits are called randomized algorithms. A non-deterministic Turing machine is a deterministic Turing machine with an added feature of non-determinism, which allows a Turing machine to have multiple possible future actions from a given state. One way to view non-determinism is that the Turing machine branches into many possible computational paths at each step, and if it solves the problem in any of these branches, it is said to have solved the problem. Clearly, this model is not meant to be a physically realizable model, it is just a theoretically interesting abstract machine that gives rise to particularly interesting complexity classes. For examples, see non-deterministic algorithm. An important factor in the creation of inequality is variation in individuals' access to education. Education, especially in an area where there is a high demand for workers, creates high wages for those with this education, however, increases in education first increase and then decrease growth as well as income inequality. As a result, those who are unable to afford an education, or choose not to pursue optional education, generally receive much lower wages. The justification for this is that a lack of education leads directly to lower incomes, and thus lower aggregate savings and investment. Conversely, education raises incomes and promotes growth because it helps to unleash the productive potential of the poor. BSkyB's standard definition broadcasts are in DVB-compliant MPEG-2, with the Sky Movies and Sky Box Office channels including optional Dolby Digital soundtracks for recent films, although these are only accessible with a Sky+ box. Sky+ HD material is broadcast using MPEG-4 and most of the HD material uses the DVB-S2 standard. Interactive services and 7-day EPG use the proprietary OpenTV system, with set-top boxes including modems for a return path. Sky News, amongst other channels, provides a pseudo-video on demand interactive service by broadcasting looping video streams. Before the foundation can be dug, contractors are typically required to verify and have existing utility lines marked, either by the utilities themselves or through a company specializing in such services. This lessens the likelihood of damage to the existing electrical, water, sewage, phone, and cable facilities, which could cause outages and potentially hazardous situations. During the construction of a building, the municipal building inspector inspects the building periodically to ensure that the construction adheres to the approved plans and the local building code. Once construction is complete and a final inspection has been passed, an occupancy permit may be issued. Between 1991 and 2000, the total area of forest lost in the Amazon rose from 415,000 to 587,000 square kilometres (160,000 to 227,000 sq mi), with most of the lost forest becoming pasture for cattle. Seventy percent of formerly forested land in the Amazon, and 91% of land deforested since 1970, is used for livestock pasture. Currently, Brazil is the second-largest global producer of soybeans after the United States. New research however, conducted by Leydimere Oliveira et al., has shown that the more rainforest is logged in the Amazon, the less precipitation reaches the area and so the lower the yield per hectare becomes. So despite the popular perception, there has been no economical advantage for Brazil from logging rainforest zones and converting these to pastoral fields. Deforestation is the conversion of forested areas to non-forested areas. The main sources of deforestation in the Amazon are human settlement and development of the land. Prior to the early 1960s, access to the forest's interior was highly restricted, and the forest remained basically intact. Farms established during the 1960s were based on crop cultivation and the slash and burn method. However, the colonists were unable to manage their fields and the crops because of the loss of soil fertility and weed invasion. The soils in the Amazon are productive for just a short period of time, so farmers are constantly moving to new areas and clearing more land. These farming practices led to deforestation and caused extensive environmental damage. Deforestation is considerable, and areas cleared of forest are visible to the naked eye from outer space. Due to its electronegativity, oxygen forms chemical bonds with almost all other elements to give corresponding oxides. The surface of most metals, such as aluminium and titanium, are oxidized in the presence of air and become coated with a thin film of oxide that passivates the metal and slows further corrosion. Many oxides of the transition metals are non-stoichiometric compounds, with slightly less metal than the chemical formula would show. For example, the mineral FeO (wüstite) is written as Fe 1 − xO, where x is usually around 0.05. During the American Civil War, Jacksonville was a key supply point for hogs and cattle being shipped from Florida to aid the Confederate cause. The city was blockaded by Union forces, who gained control of the nearby Fort Clinch. Though no battles were fought in Jacksonville proper, the city changed hands several times between Union and Confederate forces. The Skirmish of the Brick Church in 1862 just outside Jacksonville proper resulted in the first Confederate victory in Florida. In February 1864 Union forces left Jacksonville and confronted a Confederate Army at the Battle of Olustee resulting in a Confederate victory. Union forces then retreated to Jacksonville and held the city for the remainder of the war. In March 1864 a Confederate cavalry confronted a Union expedition resulting in the Battle of Cedar Creek. Warfare and the long occupation left the city disrupted after the war. Engineering News-Record (ENR) is a trade magazine for the construction industry. Each year, ENR compiles and reports on data about the size of design and construction companies. They publish a list of the largest companies in the United States (Top-40) and also a list the largest global firms (Top-250, by amount of work they are doing outside their home country). In 2014, ENR compiled the data in nine market segments. It was divided as transportation, petroleum, buildings, power, industrial, water, manufacturing, sewer/waste, telecom, hazardous waste plus a tenth category for other projects. In their reporting on the Top 400, they used data on transportation, sewer, hazardous waste and water to rank firms as heavy contractors. Fresno is the largest U.S. city not directly linked to an Interstate highway. When the Interstate Highway System was created in the 1950s, the decision was made to build what is now Interstate 5 on the west side of the Central Valley, and thus bypass many of the population centers in the region, instead of upgrading what is now State Route 99. Due to rapidly raising population and traffic in cities along SR 99, as well as the desirability of Federal funding, much discussion has been made to upgrade it to interstate standards and eventually incorporate it into the interstate system, most likely as Interstate 9. Major improvements to signage, lane width, median separation, vertical clearance, and other concerns are currently underway. Giuga's conjecture says that this equation is also a sufficient condition for p to be prime. Another consequence of Fermat's little theorem is the following: if p is a prime number other than 2 and 5, 1/p is always a recurring decimal, whose period is p − 1 or a divisor of p − 1. The fraction 1/p expressed likewise in base q (rather than base 10) has similar effect, provided that p is not a prime factor of q. Wilson's theorem says that an integer p > 1 is prime if and only if the factorial (p − 1)! + 1 is divisible by p. Moreover, an integer n > 4 is composite if and only if (n − 1)! is divisible by n. Harbor improvements since the late 19th century have made Jacksonville a major military and civilian deep-water port. Its riverine location facilitates two United States Navy bases and the Port of Jacksonville, Florida's third largest seaport. The two US Navy bases, Blount Island Command and the nearby Naval Submarine Base Kings Bay form the third largest military presence in the United States. Significant factors in the local economy include services such as banking, insurance, healthcare and logistics. As with much of Florida, tourism is also important to the Jacksonville area, particularly tourism related to golf. People from Jacksonville may be called "Jacksonvillians" or "Jaxsons" (also spelled "Jaxons"). Historically, Victoria has been the base for the manufacturing plants of the major car brands Ford, Toyota and Holden; however, closure announcements by all three companies in the 21st century will mean that Australia will no longer be a base for the global car industry, with Toyota's statement in February 2014 outlining a closure year of 2017. Holden's announcement occurred in May 2013, followed by Ford's decision in December of the same year (Ford's Victorian plants—in Broadmeadows and Geelong—will close in October 2016). Hospital pharmacies can often be found within the premises of the hospital. Hospital pharmacies usually stock a larger range of medications, including more specialized medications, than would be feasible in the community setting. Most hospital medications are unit-dose, or a single dose of medicine. Hospital pharmacists and trained pharmacy technicians compound sterile products for patients including total parenteral nutrition (TPN), and other medications given intravenously. This is a complex process that requires adequate training of personnel, quality assurance of products, and adequate facilities. Several hospital pharmacies have decided to outsource high risk preparations and some other compounding functions to companies who specialize in compounding. The high cost of medications and drug-related technology, combined with the potential impact of medications and pharmacy services on patient-care outcomes and patient safety, make it imperative that hospital pharmacies perform at the highest level possible. Immunology is strongly experimental in everyday practice but is also characterized by an ongoing theoretical attitude. Many theories have been suggested in immunology from the end of the nineteenth century up to the present time. The end of the 19th century and the beginning of the 20th century saw a battle between "cellular" and "humoral" theories of immunity. According to the cellular theory of immunity, represented in particular by Elie Metchnikoff, it was cells – more precisely, phagocytes – that were responsible for immune responses. In contrast, the humoral theory of immunity, held, among others, by Robert Koch and Emil von Behring, stated that the active immune agents were soluble components (molecules) found in the organism’s “humors” rather than its cells. In 2005, parts of the Amazon basin experienced the worst drought in one hundred years, and there were indications that 2006 could have been a second successive year of drought. A July 23, 2006 article in the UK newspaper The Independent reported Woods Hole Research Center results showing that the forest in its present form could survive only three years of drought. Scientists at the Brazilian National Institute of Amazonian Research argue in the article that this drought response, coupled with the effects of deforestation on regional climate, are pushing the rainforest towards a "tipping point" where it would irreversibly start to die. It concludes that the forest is on the brink of being turned into savanna or desert, with catastrophic consequences for the world's climate. In addition to the General Assembly Hall, the Parliament also used buildings rented from the City of Edinburgh Council. The former administrative building of Lothian Regional Council on George IV Bridge was used for the MSP's offices. Following the move to Holyrood in 2004 this building was demolished. The former Midlothian County Buildings facing Parliament Square, High Street and George IV Bridge in Edinburgh (originally built as the headquarters of the pre-1975 Midlothian County Council) housed the Parliament's visitors' centre and shop, whilst the main hall was used as the Parliament's principal committee room. In many countries, there is a Gender pay gap in favor of males in the labor market. Several factors other than discrimination may contribute to this gap. On average, women are more likely than men to consider factors other than pay when looking for work, and may be less willing to travel or relocate. Thomas Sowell, in his book Knowledge and Decisions, claims that this difference is due to women not taking jobs due to marriage or pregnancy, but income studies show that that does not explain the entire difference. A U.S. Census's report stated that in US once other factors are accounted for there is still a difference in earnings between women and men. The income gap in other countries ranges from 53% in Botswana to -40% in Bahrain. In recent years the characteristic that has strongly correlated with health in developed countries is income inequality. Creating an index of "Health and Social Problems" from nine factors, authors Richard Wilkinson and Kate Pickett found health and social problems "more common in countries with bigger income inequalities", and more common among states in the US with larger income inequalities. Other studies have confirmed this relationship. The UNICEF index of "child well-being in rich countries", studying 40 indicators in 22 countries, correlates with greater equality but not per capita income. In the 1910s, New York–based filmmakers were attracted to Jacksonville's warm climate, exotic locations, excellent rail access, and cheap labor. Over the course of the decade, more than 30 silent film studios were established, earning Jacksonville the title of "Winter Film Capital of the World". However, the emergence of Hollywood as a major film production center ended the city's film industry. One converted movie studio site, Norman Studios, remains in Arlington; It has been converted to the Jacksonville Silent Film Museum at Norman Studios. In the United States, the industry in 2014 has around $960 billion in annual revenue according to statistics tracked by the Census Bureau, of which $680 billion is private (split evenly between residential and nonresidential) and the remainder is government. As of 2005, there were about 667,000 firms employing 1 million contractors (200,000 general contractors, 38,000 heavy, and 432,000 specialty); the average contractor employed fewer than 10 employees. As a whole, the industry employed an estimated 5.8 million as of April 2013, with a 13.2% unemployment rate. In the United States, approximately 828,000 women were employed in the construction industry as of 2011. In the arts and entertainment, minimalist composer Philip Glass, dancer, choreographer and leader in the field of dance anthropology Katherine Dunham, Bungie founder and developer of the Halo video game series Alex Seropian, Serial host Sarah Koenig, actor Ed Asner, Pulitzer Prize for Criticism winning film critic and the subject of the 2014 documentary film Life Itself Roger Ebert, director, writer, and comedian Mike Nichols, film director and screenwriter Philip Kaufman, and Carl Van Vechten, photographer and writer, are graduates. Many questions regarding prime numbers remain open, such as Goldbach's conjecture (that every even integer greater than 2 can be expressed as the sum of two primes), and the twin prime conjecture (that there are infinitely many pairs of primes whose difference is 2). Such questions spurred the development of various branches of number theory, focusing on analytic or algebraic aspects of numbers. Primes are used in several routines in information technology, such as public-key cryptography, which makes use of properties such as the difficulty of factoring large numbers into their prime factors. Prime numbers give rise to various generalizations in other mathematical domains, mainly algebra, such as prime elements and prime ideals. Many types of Turing machines are used to define complexity classes, such as deterministic Turing machines, probabilistic Turing machines, non-deterministic Turing machines, quantum Turing machines, symmetric Turing machines and alternating Turing machines. They are all equally powerful in principle, but when resources (such as time or space) are bounded, some of these may be more powerful than others. Mortgage bankers, accountants, and cost engineers are likely participants in creating an overall plan for the financial management of the building construction project. The presence of the mortgage banker is highly likely, even in relatively small projects since the owner's equity in the property is the most obvious source of funding for a building project. Accountants act to study the expected monetary flow over the life of the project and to monitor the payouts throughout the process. Cost engineers and estimators apply expertise to relate the work and materials involved to a proper valuation. Cost overruns with government projects have occurred when the contractor identified change orders or project changes that increased costs, which are not subject to competition from other firms as they have already been eliminated from consideration after the initial bid. Neoclassical economics views inequalities in the distribution of income as arising from differences in value added by labor, capital and land. Within labor income distribution is due to differences in value added by different classifications of workers. In this perspective, wages and profits are determined by the marginal value added of each economic actor (worker, capitalist/business owner, landlord). Thus, in a market economy, inequality is a reflection of the productivity gap between highly-paid professions and lower-paid professions. Neutrophils and macrophages are phagocytes that travel throughout the body in pursuit of invading pathogens. Neutrophils are normally found in the bloodstream and are the most abundant type of phagocyte, normally representing 50% to 60% of the total circulating leukocytes. During the acute phase of inflammation, particularly as a result of bacterial infection, neutrophils migrate toward the site of inflammation in a process called chemotaxis, and are usually the first cells to arrive at the scene of infection. Macrophages are versatile cells that reside within tissues and produce a wide array of chemicals including enzymes, complement proteins, and regulatory factors such as interleukin 1. Macrophages also act as scavengers, ridding the body of worn-out cells and other debris, and as antigen-presenting cells that activate the adaptive immune system. Notable faculty in physics have included the speed of light calculator A. A. Michelson, elementary charge calculator Robert A. Millikan, discoverer of the Compton Effect Arthur H. Compton, the creator of the first nuclear reactor Enrico Fermi, "the father of the hydrogen bomb" Edward Teller, "one of the most brilliant and productive experimental physicists of the twentieth century" Luis Walter Alvarez, Murray Gell-Mann who introduced the quark, second female Nobel laureate Maria Goeppert-Mayer, the youngest American winner of the Nobel Prize Tsung-Dao Lee, and astrophysicist Subrahmanyan Chandrasekhar. OPEC soon lost its preeminent position, and in 1981, its production was surpassed by that of other countries. Additionally, its own member nations were divided. Saudi Arabia, trying to recover market share, increased production, pushing prices down, shrinking or eliminating profits for high-cost producers. The world price, which had peaked during the 1979 energy crisis at nearly $40 per barrel, decreased during the 1980s to less than $10 per barrel. Adjusted for inflation, oil briefly fell back to pre-1973 levels. This "sale" price was a windfall for oil-importing nations, both developing and developed. On October 6, 1973, Syria and Egypt, with support from other Arab nations, launched a surprise attack on Israel, on Yom Kippur. This renewal of hostilities in the Arab–Israeli conflict released the underlying economic pressure on oil prices. At the time, Iran was the world's second-largest oil exporter and a close US ally. Weeks later, the Shah of Iran said in an interview: "Of course [the price of oil] is going to rise... Certainly! And how!... You've [Western nations] increased the price of the wheat you sell us by 300 percent, and the same for sugar and cement... You buy our crude oil and sell it back to us, refined as petrochemicals, at a hundred times the price you've paid us... It's only fair that, from now on, you should pay more for oil. Let's say ten times more." One key figure in the plans for what would come to be known as American Empire, was a geographer named Isiah Bowman. Bowman was the director of the American Geographical Society in 1914. Three years later in 1917, he was appointed to then President Woodrow Wilson's inquiry in 1917. The inquiry was the idea of President Wilson and the American delegation from the Paris Peace Conference. The point of this inquiry was to build a premise that would allow for U.S authorship of a 'new world' which was to be characterized by geographical order. As a result of his role in the inquiry, Isiah Bowman would come to be known as Wilson's geographer. Other: Civil rights leader W. E. B. Du Bois; philosopher Henry David Thoreau; authors Ralph Waldo Emerson and William S. Burroughs; educators Werner Baer, Harlan Hanson; poets Wallace Stevens, T. S. Eliot and E. E. Cummings; conductor Leonard Bernstein; cellist Yo Yo Ma; pianist and composer Charlie Albright; composer John Alden Carpenter; comedian, television show host and writer Conan O'Brien; actors Tatyana Ali, Nestor Carbonell, Matt Damon, Fred Gwynne, Hill Harper, Rashida Jones, Tommy Lee Jones, Ashley Judd, Jack Lemmon, Natalie Portman, Mira Sorvino, Elisabeth Shue, and Scottie Thompson; film directors Darren Aronofsky, Terrence Malick, Mira Nair, and Whit Stillman; architect Philip Johnson; musicians Rivers Cuomo, Tom Morello, and Gram Parsons; musician, producer and composer Ryan Leslie; serial killer Ted Kaczynski; programmer and activist Richard Stallman; NFL quarterback Ryan Fitzpatrick; NFL center Matt Birk; NBA player Jeremy Lin; US Ski Team skier Ryan Max Riley; physician Sachin H. Jain; physicist J. Robert Oppenheimer; computer pioneer and inventor An Wang; Tibetologist George de Roerich; and Marshall Admiral Isoroku Yamamoto. Packet switching contrasts with another principal networking paradigm, circuit switching, a method which pre-allocates dedicated network bandwidth specifically for each communication session, each having a constant bit rate and latency between nodes. In cases of billable services, such as cellular communication services, circuit switching is characterized by a fee per unit of connection time, even when no data is transferred, while packet switching may be characterized by a fee per unit of information transmitted, such as characters, packets, or messages. Prime ideals are the points of algebro-geometric objects, via the notion of the spectrum of a ring. Arithmetic geometry also benefits from this notion, and many concepts exist in both geometry and number theory. For example, factorization or ramification of prime ideals when lifted to an extension field, a basic problem of algebraic number theory, bears some resemblance with ramification in geometry. Such ramification questions occur even in number-theoretic questions solely concerned with integers. For example, prime ideals in the ring of integers of quadratic number fields can be used in proving quadratic reciprocity, a statement that concerns the solvability of quadratic equations Since the 1920s, motion pictures, petroleum and aircraft manufacturing have been major industries. In one of the richest agricultural regions in the U.S., cattle and citrus were major industries until farmlands were turned into suburbs. Although military spending cutbacks have had an impact, aerospace continues to be a major factor. Southern California's economy is diverse and one of the largest in the United States. It is dominated and heavily dependent upon abundance of petroleum, as opposed to other regions where automobiles not nearly as dominant, the vast majority of transport runs on this fuel. Southern California is famous for tourism and Hollywood (film, television, and music). Other industries include software, automotive, ports, finance, tourism, biomedical, and regional logistics. The region was a leader in the housing bubble 2001–2007, and has been heavily impacted by the housing crash. Students at the University of Chicago run over 400 clubs and organizations known as Recognized Student Organizations (RSOs). These include cultural and religious groups, academic clubs and teams, and common-interest organizations. Notable extracurricular groups include the University of Chicago College Bowl Team, which has won 118 tournaments and 15 national championships, leading both categories internationally. The university's competitive Model United Nations team was the top ranked team in North America in 2013-14 and 2014-2015. Among notable RSOs are the nation's longest continuously running student film society Doc Films, organizing committee for the University of Chicago Scavenger Hunt, the twice-weekly student newspaper The Chicago Maroon, the alternative weekly student newspaper South Side Weekly, the nation's second oldest continuously running student improvisational theater troupe Off-Off Campus, and the university-owned radio station WHPK. Studies on income inequality and growth have sometimes found evidence confirming the Kuznets curve hypothesis, which states that with economic development, inequality first increases, then decreases. Economist Thomas Piketty challenges this notion, claiming that from 1914 to 1945 wars and "violent economic and political shocks" reduced inequality. Moreover, Piketty argues that the "magical" Kuznets curve hypothesis, with its emphasis on the balancing of economic growth in the long run, cannot account for the significant increase in economic inequality throughout the developed world since the 1970s. Telenet was the first FCC-licensed public data network in the United States. It was founded by former ARPA IPTO director Larry Roberts as a means of making ARPANET technology public. He had tried to interest AT&T in buying the technology, but the monopoly's reaction was that this was incompatible with their future. Bolt, Beranack and Newman (BBN) provided the financing. It initially used ARPANET technology but changed the host interface to X.25 and the terminal interface to X.29. Telenet designed these protocols and helped standardize them in the CCITT. Telenet was incorporated in 1973 and started operations in 1975. It went public in 1979 and was then sold to GTE. The FSO Car Factory was established in 1951. A number of vehicles have been assembled there over the decades, including the Warszawa, Syrena, Fiat 125p (under license from Fiat, later renamed FSO 125p when the license expired) and the Polonez. The last two models listed were also sent abroad and assembled in a number of other countries, including Egypt and Colombia. In 1995 the factory was purchased by the South Korean car manufacturer Daewoo, which assembled the Tico, Espero, Nubia, Tacuma, Leganza, Lanos and Matiz there for the European market. In 2005 the factory was sold to AvtoZAZ, a Ukrainian car manufacturer which assembled there the Chevrolet Aveo. The license for the production of the Aveo expired in February 2011 and has since not been renewed. Currently the company is defunct. The IPCC concentrates its activities on the tasks allotted to it by the relevant WMO Executive Council and UNEP Governing Council resolutions and decisions as well as on actions in support of the UNFCCC process. While the preparation of the assessment reports is a major IPCC function, it also supports other activities, such as the Data Distribution Centre and the National Greenhouse Gas Inventories Programme, required under the UNFCCC. This involves publishing default emission factors, which are factors used to derive emissions estimates based on the levels of fuel consumption, industrial production and so on. The Mongol rulers patronized the Yuan printing industry. Chinese printing technology was transferred to the Mongols through Kingdom of Qocho and Tibetan intermediaries. Some Yuan documents such as Wang Zhen's Nong Shu were printed with earthenware movable type, a technology invented in the 12th century. However, most published works were still produced through traditional block printing techniques. The publication of a Taoist text inscribed with the name of Töregene Khatun, Ögedei's wife, is one of the first printed works sponsored by the Mongols. In 1273, the Mongols created the Imperial Library Directorate, a government-sponsored printing office. The Yuan government established centers for printing throughout China. Local schools and government agencies were funded to support the publishing of books. The Standard Industrial Classification and the newer North American Industry Classification System have a classification system for companies that perform or otherwise engage in construction. To recognize the differences of companies in this sector, it is divided into three subsectors: building construction, heavy and civil engineering construction, and specialty trade contractors. There are also categories for construction service firms (e.g., engineering, architecture) and construction managers (firms engaged in managing construction projects without assuming direct financial responsibility for completion of the construction project). The UChicago Arts program joins academic departments and programs in the Division of the Humanities and the College, as well as professional organizations including the Court Theatre, the Oriental Institute, the Smart Museum of Art, the Renaissance Society, University of Chicago Presents, and student arts organizations. The university has an artist-in-residence program and scholars in performance studies, contemporary art criticism, and film history. It has offered a doctorate in music composition since 1933 and in Cinema & Media studies since 2000, a master of fine arts in visual arts (early 1970s), and a master of arts in the humanities with a creative writing track (2000). It has bachelor's degree programs in visual arts, music, and art history, and, more recently, Cinema & Media studies (1996) and theater & performance studies (2002). The College's general education core includes a “dramatic, music, and visual arts” requirement, requiring students to study the history of the arts, stage desire, or begin working with sculpture. Several thousand major and non-major undergraduates enroll annually in creative and performing arts classes. UChicago is often considered the birthplace of improvisational comedy as the Compass Players student comedy troupe evolved into The Second City improv theater troupe in 1959. The Reva and David Logan Center for the Arts opened in October 2012, five years after a $35 million gift from alumnus David Logan and his wife Reva. The center includes spaces for exhibitions, performances, classes, and media production. The Logan Center was designed by Tod Williams and Billie Tsien. This building is actually entirely glass. The brick is a facade designed to keep the glass safe from the wind. The architects later removed sections of the bricks when pressure arose in the form of complaints that the views of the city were blocked. The clinical pharmacist's role involves creating a comprehensive drug therapy plan for patient-specific problems, identifying goals of therapy, and reviewing all prescribed medications prior to dispensing and administration to the patient. The review process often involves an evaluation of the appropriateness of the drug therapy (e.g., drug choice, dose, route, frequency, and duration of therapy) and its efficacy. The pharmacist must also monitor for potential drug interactions, adverse drug reactions, and assess patient drug allergies while designing and initiating a drug therapy plan. The crisis had a major impact on international relations and created a rift within NATO. Some European nations and Japan sought to disassociate themselves from United States foreign policy in the Middle East to avoid being targeted by the boycott. Arab oil producers linked any future policy changes to peace between the belligerents. To address this, the Nixon Administration began multilateral negotiations with the combatants. They arranged for Israel to pull back from the Sinai Peninsula and the Golan Heights. By January 18, 1974, US Secretary of State Henry Kissinger had negotiated an Israeli troop withdrawal from parts of the Sinai Peninsula. The promise of a negotiated settlement between Israel and Syria was enough to convince Arab oil producers to lift the embargo in March 1974. The fundamental theorem of arithmetic continues to hold in unique factorization domains. An example of such a domain is the Gaussian integers Z[i], that is, the set of complex numbers of the form a + bi where i denotes the imaginary unit and a and b are arbitrary integers. Its prime elements are known as Gaussian primes. Not every prime (in Z) is a Gaussian prime: in the bigger ring Z[i], 2 factors into the product of the two Gaussian primes (1 + i) and (1 − i). Rational primes (i.e. prime elements in Z) of the form 4k + 3 are Gaussian primes, whereas rational primes of the form 4k + 1 are not. The integer factorization problem is the computational problem of determining the prime factorization of a given integer. Phrased as a decision problem, it is the problem of deciding whether the input has a factor less than k. No efficient integer factorization algorithm is known, and this fact forms the basis of several modern cryptographic systems, such as the RSA algorithm. The integer factorization problem is in NP and in co-NP (and even in UP and co-UP). If the problem is NP-complete, the polynomial time hierarchy will collapse to its first level (i.e., NP will equal co-NP). The best known algorithm for integer factorization is the general number field sieve, which takes time O(e(64/9)1/3(n.log 2)1/3(log (n.log 2))2/3) to factor an n-bit integer. However, the best known quantum algorithm for this problem, Shor's algorithm, does run in polynomial time. Unfortunately, this fact doesn't say much about where the problem lies with respect to non-quantum complexity classes. The judicial branch of the EU has played an important role in the development of EU law, by assuming the task of interpreting the treaties, and accelerating economic and political integration. Today the Court of Justice of the European Union (CJEU) is the main judicial body, within which there is a higher European Court of Justice (commonly abbreviated as ECJ) that deals with cases that contain more public importance, and a General Court that deals with issues of detail but without general importance. There is also a Civil Service Tribunal to deal with EU staff issues, and then a separate Court of Auditors. Under the Treaty on European Union article 19(2) there is one judge from each member state, 28 at present, who are supposed to "possess the qualifications required for appointment to the highest judicial offices" (or for the General Court, the "ability required for appointment to high judicial office"). A president is elected by the judges for three years. Under TEU article 19(3) is to be the ultimate court to interpret questions of EU law. In fact, most EU law is applied by member state courts (the English Court of Appeal, the German Bundesgerichtshof, the Belgian Cour du travail, etc.) but they can refer questions to the EU court for a preliminary ruling. The CJEU's duty is to "ensure that in the interpretation and application of the Treaties the law is observed", although realistically it has the ability to expand and develop the law according to the principles it deems to be appropriate. Arguably this has been done through both seminal and controversial judgments, including Van Gend en Loos, Mangold v Helm, and Kadi v Commission. The modern trend in design is toward integration of previously separated specialties, especially among large firms. In the past, architects, interior designers, engineers, developers, construction managers, and general contractors were more likely to be entirely separate companies, even in the larger firms. Presently, a firm that is nominally an "architecture" or "construction management" firm may have experts from all related fields as employees, or to have an associated company that provides each necessary skill. Thus, each such firm may offer itself as "one-stop shopping" for a construction project, from beginning to end. This is designated as a "design build" contract where the contractor is given a performance specification and must undertake the project from design to construction, while adhering to the performance specifications. The motion picture, television, and music industry is centered on the Los Angeles in southern California. Hollywood, a district within Los Angeles, is also a name associated with the motion picture industry. Headquartered in southern California are The Walt Disney Company (which also owns ABC), Sony Pictures, Universal, MGM, Paramount Pictures, 20th Century Fox, and Warner Brothers. Universal, Warner Brothers, and Sony also run major record companies as well. The owner produces a list of requirements for a project, giving an overall view of the project's goals. Several D&B contractors present different ideas about how to accomplish these goals. The owner selects the ideas he or she likes best and hires the appropriate contractor. Often, it is not just one contractor, but a consortium of several contractors working together. Once these have been hired, they begin building the first phase of the project. As they build phase 1, they design phase 2. This is in contrast to a design-bid-build contract, where the project is completely designed by the owner, then bid on, then completed. The secondary level includes schools offering years 7 through 12 (year twelve is known as lower sixth) and year 13 (upper sixth). This category includes university-preparatory schools or "prep schools", boarding schools and day schools. Tuition at private secondary schools varies from school to school and depends on many factors, including the location of the school, the willingness of parents to pay, peer tuitions and the school's financial endowment. High tuition, schools claim, is used to pay higher salaries for the best teachers and also used to provide enriched learning environments, including a low student to teacher ratio, small class sizes and services, such as libraries, science laboratories and computers. Some private schools are boarding schools and many military academies are privately owned or operated as well. The unusually high concentration of oxygen gas on Earth is the result of the oxygen cycle. This biogeochemical cycle describes the movement of oxygen within and between its three main reservoirs on Earth: the atmosphere, the biosphere, and the lithosphere. The main driving factor of the oxygen cycle is photosynthesis, which is responsible for modern Earth's atmosphere. Photosynthesis releases oxygen into the atmosphere, while respiration and decay remove it from the atmosphere. In the present equilibrium, production and consumption occur at the same rate of roughly 1/2000th of the entire atmospheric oxygen per year. This is the most common method of construction procurement and is well established and recognized. In this arrangement, the architect or engineer acts as the project coordinator. His or her role is to design the works, prepare the specifications and produce construction drawings, administer the contract, tender the works, and manage the works from inception to completion. There are direct contractual links between the architect's client and the main contractor. Any subcontractor has a direct contractual relationship with the main contractor. The procedure continues until the building is ready to occupy. This vibrant and culturally diverse area of retail businesses and residences experienced a renewal after a significant decline in the late 1960s and 1970s.[citation needed] After decades of neglect and suburban flight, the neighborhood revival followed the re-opening of the Tower Theatre in the late 1970s, which at that time showed second and third run movies, along with classic films. Roger Rocka's Dinner Theater & Good Company Players also opened nearby in 1978,[citation needed] at Olive and Wishon Avenues. Fresno native Audra McDonald performed in the leading roles of Evita and The Wiz at the theater while she was a high school student. McDonald subsequently became a leading performer on Broadway in New York City and a Tony award winning actress. Also in the Tower District is Good Company Players' 2nd Space Theatre. Until the early 1980s, industry was a major source of water pollution. Although many plants and factories can be found along the Rhine up into Switzerland, it is along the Lower Rhine that the bulk of them are concentrated, as the river passes the major cities of Cologne, Düsseldorf and Duisburg. Duisburg is the home of Europe's largest inland port and functions as a hub to the sea ports of Rotterdam, Antwerp and Amsterdam. The Ruhr, which joins the Rhine in Duisburg, is nowadays a clean river, thanks to a combination of stricter environmental controls, a transition from heavy industry to light industry and cleanup measures, such as the reforestation of Slag and brownfields. The Ruhr currently provides the region with drinking water. It contributes 70 m3/s (2,500 cu ft/s) to the Rhine. Other rivers in the Ruhr Area, above all, the Emscher, still carry a considerable degree of pollution. Upper and lower bounds are usually stated using the big O notation, which hides constant factors and smaller terms. This makes the bounds independent of the specific details of the computational model used. For instance, if T(n) = 7n2 + 15n + 40, in big O notation one would write T(n) = O(n2).