# Copyright 2020 Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany # # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, software # distributed under the License is distributed on an "AS IS" BASIS, # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. # See the License for the specific language governing permissions and # limitations under the License. import numpy as np import torch import torch.nn as nn from nnunet.training.network_training.nnUNetTrainerV2 import nnUNetTrainerV2 class FocalLoss(nn.Module): """ copy from: https://github.com/Hsuxu/Loss_ToolBox-PyTorch/blob/master/FocalLoss/FocalLoss.py This is a implementation of Focal Loss with smooth label cross entropy supported which is proposed in 'Focal Loss for Dense Object Detection. (https://arxiv.org/abs/1708.02002)' Focal_Loss= -1*alpha*(1-pt)*log(pt) :param num_class: :param alpha: (tensor) 3D or 4D the scalar factor for this criterion :param gamma: (float,double) gamma > 0 reduces the relative loss for well-classified examples (p>0.5) putting more focus on hard misclassified example :param smooth: (float,double) smooth value when cross entropy :param balance_index: (int) balance class index, should be specific when alpha is float :param size_average: (bool, optional) By default, the losses are averaged over each loss element in the batch. """ def __init__(self, apply_nonlin=None, alpha=None, gamma=2, balance_index=0, smooth=1e-5, size_average=True): super(FocalLoss, self).__init__() self.apply_nonlin = apply_nonlin self.alpha = alpha self.gamma = gamma self.balance_index = balance_index self.smooth = smooth self.size_average = size_average if self.smooth is not None: if self.smooth < 0 or self.smooth > 1.0: raise ValueError('smooth value should be in [0,1]') def forward(self, logit, target): if self.apply_nonlin is not None: logit = self.apply_nonlin(logit) num_class = logit.shape[1] if logit.dim() > 2: # flatten spatial dimensions N,C,d1,d2 -> N,C,m (m=d1*d2*...) logit = logit.view(logit.size(0), logit.size(1), -1) logit = logit.permute(0, 2, 1).contiguous() logit = logit.view(-1, logit.size(-1)) target = torch.squeeze(target, 1) target = target.view(-1, 1) # print(logit.shape, target.shape) alpha = self.alpha if alpha is None: alpha = torch.ones(num_class, 1) elif isinstance(alpha, (list, np.ndarray)): assert len(alpha) == num_class alpha = torch.FloatTensor(alpha).view(num_class, 1) alpha = alpha / alpha.sum() elif isinstance(alpha, float): alpha = torch.ones(num_class, 1) alpha = alpha * (1 - self.alpha) alpha[self.balance_index] = self.alpha else: raise TypeError(f'Unsupported alpha type: {type(alpha)}') if alpha.device != logit.device: alpha = alpha.to(logit.device) idx = target.cpu().long() one_hot_key = torch.FloatTensor(target.size(0), num_class).zero_() one_hot_key = one_hot_key.scatter_(1, idx, 1) if one_hot_key.device != logit.device: one_hot_key = one_hot_key.to(logit.device) if self.smooth: one_hot_key = torch.clamp( one_hot_key, self.smooth/(num_class-1), 1.0 - self.smooth) pt = (one_hot_key * logit).sum(1) + self.smooth logpt = pt.log() gamma = self.gamma alpha = alpha[idx] alpha = torch.squeeze(alpha) loss = -1 * alpha * torch.pow((1 - pt), gamma) * logpt if self.size_average: loss = loss.mean() else: loss = loss.sum() return loss class nnUNetTrainerV2_focalLossAlpha75(nnUNetTrainerV2): def __init__(self, plans_file, fold, output_folder=None, dataset_directory=None, batch_dice=True, stage=None, unpack_data=True, deterministic=True, fp16=False): super().__init__(plans_file, fold, output_folder, dataset_directory, batch_dice, stage, unpack_data, deterministic, fp16) print("Setting up FocalLoss(alpha=[0.75, 0.25], apply_nonlin=nn.Softmax())") self.loss = FocalLoss(alpha=[0.75, 0.25], apply_nonlin=nn.Softmax()) class nnUNetTrainerV2_focalLossAlpha75_checkpoints(nnUNetTrainerV2_focalLossAlpha75): def __init__(self, plans_file, fold, output_folder=None, dataset_directory=None, batch_dice=True, stage=None, unpack_data=True, deterministic=True, fp16=False): super().__init__(plans_file, fold, output_folder, dataset_directory, batch_dice, stage, unpack_data, deterministic, fp16) print("Saving checkpoint every 50th epoch") self.save_latest_only = False class nnUNetTrainerV2_focalLossAlpha75_checkpoints2(nnUNetTrainerV2_focalLossAlpha75_checkpoints): def __init__(self, plans_file, fold, output_folder=None, dataset_directory=None, batch_dice=True, stage=None, unpack_data=True, deterministic=True, fp16=False): super().__init__(plans_file, fold, output_folder, dataset_directory, batch_dice, stage, unpack_data, deterministic, fp16) pass # this is just to get a new Trainer directory class nnUNetTrainerV2_focalLossAlpha75_checkpoints3(nnUNetTrainerV2_focalLossAlpha75_checkpoints): def __init__(self, plans_file, fold, output_folder=None, dataset_directory=None, batch_dice=True, stage=None, unpack_data=True, deterministic=True, fp16=False): super().__init__(plans_file, fold, output_folder, dataset_directory, batch_dice, stage, unpack_data, deterministic, fp16) pass # this is just to get a new Trainer directory