diff --git "a/data/PROTAC-DB-Scraped.csv" "b/data/PROTAC-DB-Scraped.csv" new file mode 100644--- /dev/null +++ "b/data/PROTAC-DB-Scraped.csv" @@ -0,0 +1,6001 @@ +Compound ID,Target,Assay (Percent degradation),DOI,DC50,Dmax,Assay (DC50/Dmax),PROTAC to Target +1,BRD7,20/12 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4/16 h treatment at 1 μM +1,BRD9,19/30 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +2,BRD7,19/27 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4/16 h treatment at 1 μM +2,BRD9,5/21 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +3,BRD9,94/93 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +4,BRD9,81/89 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +5,BRD9,0/19 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +5,BRD7,0/14 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4/16 h treatment at 1 μM +6,BRD9,0/14 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4/16 h treatment at 1 μM +6,BRD7,19/14 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4/16 h treatment at 1 μM +7,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +7,BRD9,23 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +8,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +8,BRD9,57 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +9,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +9,BRD9,7 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +10,BRD9,26 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +10,BRD7,5 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +11,BRD7,3 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +11,BRD9,,10.1021/acs.jmedchem.8b01413,560,80,Degradation of BRD9 in HeLa cells after 4 h treatment, +12,BRD7,12 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +12,BRD9,50 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +13,BRD7,11 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +13,BRD9,9 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +14,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +14,BRD9,32 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +15,BRD9,1 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +15,BRD7,5 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +16,BRD9,8 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in HeLa cells after 4 h treatment at 1 μM +16,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in HeLa cells after 4 h treatment at 1 μM +17,BRD7,37 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +17,BRD9,37 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +18,BRD9,6 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +18,BRD7,2 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +19,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +19,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +20,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +20,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +21,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +21,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +22,BRD9,,10.1021/acs.jmedchem.8b01413,1.76,95,Degradation of BRD9 in RI-1 cells after 8 h treatment, +22,BRD7,,10.1021/acs.jmedchem.8b01413,34.5,,Degradation of HiBiT-BRD7 in HEK293 cells after 24 h treatment using CRISPR/Cas9, +22,BRD7,,10.1021/acs.jmedchem.8b01413,4.5,95,Degradation of BRD7 in RI-1 cells after 8 h treatment, +22,BRD9,,10.1021/acs.jmedchem.8b01413,2/8,,Degradation of BRD9 in EOL-1/A-204 cells after 18 h treatment on a WES capillary electrophoresis instrument, +22,BRD9,,10.1021/acs.jmedchem.8b01413,4,,Degradation of HiBiT-BRD9 in HEK293 cells after 24 h treatment using CRISPR/Cas9, +23,BRD9,35 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +23,BRD7,35 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +24,BRD9,31 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +24,BRD7,17 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +25,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +25,BRD9,11 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +26,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +26,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +27,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +27,BRD9,1 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +28,BRD9,5 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +28,BRD7,8 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +29,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +29,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +30,BRD7,2 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +30,BRD9,11 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +31,BRD9,5 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +31,BRD7,15 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +32,BRD7,30 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +32,BRD9,32 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +33,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +33,BRD9,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +34,BRD7,0 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +34,BRD9,8 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +35,BRD7,3 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD7 degradation in RI-1 cells after 2 h treatment at 1 μM +35,BRD9,6 (WB),10.1021/acs.jmedchem.8b01413,,,,% BRD9 degradation in RI-1 cells after 2 h treatment at 1 μM +36,MCL1,11/37/37/42/0 (WB),10.1021/acs.jmedchem.9b00455,,,,% MCL1 degradation in OPM2 cells after 48 h treatment at 25/100/250/500/1000 nM +37,MDM2,50/70/90 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 3/10/30 nM +38,MDM2,80/90/93 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 3/10/30 nM +39,MDM2,0/10 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 100/300 nM +40,MDM2,50/60 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 30/100 nM +41,MDM2,70/70 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 10/30 nM +42,MDM2,60/80 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 10/30 nM +43,MDM2,10/40 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 30/100 nM +44,MDM2,0/30 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 100/300 nM +45,MDM2,70/60 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 10/30 nM +46,MDM2,70/60 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 10/30 nM +47,MDM2,,10.1021/acs.jmedchem.8b00909,,,, +48,MDM2,,10.1021/acs.jmedchem.8b00909,,,, +49,MDM2,60/93/96/98 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 1/3/10/30 nM +50,MDM2,80/95/98/99 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 1/3/10/30 nM +51,MDM2,,10.1021/acs.jmedchem.8b00909,,,, +52,MDM2,60/80/70 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 3/10/30 nM +53,MDM2,60/80/80 (WB),10.1021/acs.jmedchem.8b00909,,,,% MDM2 degradation in RS4;11 cells after 2 h treatment at 3/10/30 nM +54,MDM2,,10.1021/acs.jmedchem.8b00909,,N.D.,, +55,MDM2,,10.1021/acs.jmedchem.8b00909,,N.D.,, +56,MDM2,,10.1021/acs.jmedchem.8b00909,,N.D.,, +57,ER,,10.1021/acs.jmedchem.8b01572,,N.D.,, +58,ER,,10.1021/acs.jmedchem.8b01572,,N.D.,, +59,ER,0/99.4/99.6/33 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100/1000 nM +60,ER,79/99.6/99.7/36 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100/1000 nM +61,ER,37/0/0 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100 nM +62,ER,10/0/8 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100 nM +63,ER,74/34/88 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100 nM +64,ER,68/92/94 (WB),10.1021/acs.jmedchem.8b01572,,,,% ER degradation in MCF-7 cells after 4 h treatment at 1/10/100 nM +115,AR,20/81/97,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +116,AR,38/80/95,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +117,AR,18/34/35,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +118,AR,76/98/99,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +118,AR,76/>95/>99,10.1021/acs.jmedchem.9b01393,7.2/1,>95/>95,Degradation of AR in LNCaP/VCaP AR+ cells after 6 h treatment,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +119,AR,65/93/78,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +120,AR,89/99/100,10.1021/acs.jmedchem.8b01631,0.86/0.76/10.4,>95/>95/>95,Degradation of AR in LNCaP/VCaP/22Rv1 cells after 24 h treatment,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +121,AR,76/99/100,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +122,AR,39/77/99,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +123,AR,<5/<5/<5,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +124,AR,<5/<5/<5,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +125,AR,43/91/96,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +126,AR,7/20/5,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +127,AR,2/25/20,10.1021/acs.jmedchem.8b01631,,,,% AR degradation in LNCaP cells after 6 h treatment at 100/1000/10000 nM +128,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +128,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +128,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +129,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +129,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +129,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +130,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +130,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +130,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +131,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +131,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +131,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +132,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +132,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +132,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +133,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +133,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +133,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +134,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +134,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +134,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +135,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +135,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +135,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +136,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +136,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +136,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +137,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +137,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +137,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +138,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +138,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +138,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +139,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +139,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +139,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +140,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +140,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +140,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +141,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +141,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +141,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +142,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +142,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +142,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +142,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +142,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +142,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +142,BRD2,,10.1158/0008-5472.CAN-16-2622,,,, +142,BRD3,,10.1158/0008-5472.CAN-16-2622,,,, +142,BRD4,,10.1158/0008-5472.CAN-16-2622,,,, +143,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +143,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +143,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +144,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +144,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +144,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +145,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +145,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +145,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +146,BRD4,,10.1021/acs.jmedchem.6b01781,490/500,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +147,BRD4,,10.1021/acs.jmedchem.6b01781,>5000/130,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +148,BRD4,,10.1021/acs.jmedchem.6b01781,>5000/1260,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +149,BRD4,,10.1021/acs.jmedchem.6b01781,450/250,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +150,BRD4,,10.1021/acs.jmedchem.6b01781,200/150,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +151,BRD4,,10.1021/acs.jmedchem.6b01781,59/550,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +152,BRD4,,10.1021/acs.jmedchem.6b01781,83/470,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +153,BRD4,,10.1021/acs.jmedchem.6b01781,240/1670,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +154,BRD4,,10.1021/acs.jmedchem.6b01781,460/3660,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +155,BRD4,,10.1021/acs.jmedchem.6b01781,630/2730,,Degradation of BRD4 in NCI-H661/NCI-H838 cells after 4h treatment, +156,SIRT2,,10.1021/acs.jmedchem.6b01872,,,, +157,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +157,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +157,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +158,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +158,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +158,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +159,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +159,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +159,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +160,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +160,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +160,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +161,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +161,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +161,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +162,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +162,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +162,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +163,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +163,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +163,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +164,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +164,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +164,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +165,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +165,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +165,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +166,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +166,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +166,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +167,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +167,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +167,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +168,PARP1,0 (WB),10.1039/c8cc07813k,,,,% PARP1 degradation in MDA-MB-231 cells after 24 h treatment at 10 μM +169,PARP1,0 (WB),10.1039/c8cc07813k,,,,% PARP1 degradation in MDA-MB-231 cells after 24 h treatment at 10 μM +170,PARP1,52 (WB),10.1039/c8cc07813k,,,,% PARP1 degradation in MDA-MB-231 cells after 24 h treatment at 10 μM +171,PARP1,0 (WB),10.1039/c8cc07813k,,,,% PARP1 degradation in MDA-MB-231 cells after 24 h treatment at 10 μM +172,PARP1,0 (WB),10.1039/c8cc07813k,,,,% PARP1 degradation in MDA-MB-231 cells after 24 h treatment at 10 μM +173,CRBN,,10.1039/c8cc09541h,,,, +174,CRBN,,10.1038/s41598-019-56177-5,367.8,85.1,Degradation of CRBN in HEK293T cells after 24h treatment, +175,CRBN,,10.1039/c8cc09541h,,,, +176,CRBN,,10.1039/c8cc09541h,1.5,,Degradation of CRBN in MM1S cells after 24h treatment, +177,CRBN,,10.1039/c8cc09541h,,,, +178,CRBN,,10.1039/c8cc09541h,,,, +179,CRBN,,10.1039/c8cc09541h,,,, +180,CRBN,,10.1039/c8cc09541h,,,, +181,p38alpha,,10.1038/s41467-018-08027-7,40.1,92.6,Degradation of p38alpha in MDA-MB-231 cells, +181,p38delta,,10.1038/s41467-018-08027-7,51.4,81.8,Degradation of p38delta in MDA-MB-231 cells, +182,p38delta,,10.1038/s41467-018-08027-7,91.7,96.7,Degradation of p38delta in MDA-MB-231 cells, +182,p38alpha,,10.1038/s41467-018-08027-7,18.8,99.4,Degradation of p38alpha in MDA-MB-231 cells, +183,p38alpha,,10.1038/s41467-018-08027-7,230,90.1,Degradation of p38alpha in MDA-MB-231 cells, +183,RIPK2,,10.1016/j.chembiol.2017.09.010,,,, +183,p38delta,,10.1016/j.chembiol.2017.09.010,,,, +183,c-Met,,10.1016/j.chembiol.2017.09.010,,,, +183,c-Met,,10.1016/j.chembiol.2017.09.009,,,, +183,p38delta,,10.1038/s41467-018-08027-7,456,54.3,Degradation of p38delta in MDA-MB-231 cells, +183,p38alpha,,10.1016/j.chembiol.2017.09.010,210,91,Degradation of p38alpha in MDA-MB-231 cells after 24 h treatment, +184,p38alpha,,10.1038/s41467-018-08027-7,9.5,99.6,Degradation of p38alpha in MDA-MB-231 cells, +184,p38delta,,10.1038/s41467-018-08027-7,1160,25.1,Degradation of p38delta in MDA-MB-231 cells, +185,p38alpha,,10.1038/s41467-018-08027-7,45.9,34.5,Degradation of p38alpha in MDA-MB-231 cells, +185,p38delta,,10.1038/s41467-018-08027-7,79.2,98.4,Degradation of p38delta in MDA-MB-231 cells, +186,p38delta,,10.1038/s41467-018-08027-7,106,43.5,Degradation of p38delta in MDA-MB-231 cells, +186,p38alpha,,10.1038/s41467-018-08027-7,127,25.3,Degradation of p38alpha in MDA-MB-231 cells, +187,p38alpha,,10.1038/s41467-018-08027-7,760,16.8,Degradation of p38alpha in MDA-MB-231 cells, +187,p38delta,,10.1038/s41467-018-08027-7,1890,78.7,Degradation of p38delta in MDA-MB-231 cells, +188,p38alpha,,10.1038/s41467-018-08027-7,304,19.9,Degradation of p38alpha in MDA-MB-231 cells, +188,p38delta,,10.1038/s41467-018-08027-7,1140,33.5,Degradation of p38delta in MDA-MB-231 cells, +189,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +189,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +190,CDK6,,10.1016/j.bmcl.2019.03.035,,,, +191,CDK6,,10.1016/j.bmcl.2019.03.035,,,, +192,CDK6,,10.1016/j.bmcl.2019.03.035,,,, +193,CDK6,,10.1016/j.bmcl.2019.03.035,,,, +194,BRD2,,10.1021/acs.orglett.9b01326,<0.5,,Degradation of BRD2, +194,BRD3,,10.1021/acs.orglett.9b01326,<0.5,,Degradation of BRD3, +194,BRD4,,10.1021/acs.orglett.9b01326,<0.5,,Degradation of BRD4, +195,ERRalpha,28/50,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +196,ERRalpha,58/85,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +197,ERRalpha,39/83/96,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 10/30/100 nM +198,ERRalpha,58/78,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +199,ERRalpha,23/71,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +200,ERRalpha,3/9,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +201,ERRalpha,79/92,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100 nM +202,ERRalpha,25/63/89,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 10/30/100 nM +203,ERRalpha,0/15/19,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100/300 nM +204,ERRalpha,0/4/10,10.1021/acsmedchemlett.9b00025,,,,% ERRalpha degradation in MDA-MB-231 cells after 4 h treatment at 30/100/300 nM +205,BTK,85 (WB),10.1039/c8cc08716d,,,,% BTK degradation in Ramos cells after 16 h treatment at 2 μM +206,BTK,,10.1039/c8cc08716d,,,, +207,BTK,,10.1039/c8cc08716d,,,, +208,BRD4,,10.1158/0008-5472.CAN-18-2918,32,98,Degradation of BRD4 in HCT116 cells after 24 h treatment, +209,BRD4,,10.1158/0008-5472.CAN-18-2918,23.1,89,Degradation of BRD4 in HCT116 cells after 24 h treatment, +210,BTK,,10.1073/pnas.1803662115,,N.D.,, +211,BTK,,10.1073/pnas.1803662115,,N.D.,, +212,BTK,,10.1073/pnas.1803662115,,33/18,, +213,BTK,,10.1073/pnas.1803662115,,34/15,, +214,BTK,,10.1073/pnas.1803662115,1487/(n/a),64/36,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +215,BTK,,10.1073/pnas.1803662115,36.9/398.5,85/68,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +216,BTK,,10.1073/pnas.1803662115,21.8/469.9,84/63,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +217,BTK,,10.1073/pnas.1803662115,4.5/90.5,87/75,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +218,BTK,,10.1073/pnas.1803662115,5.9/217.7,85/71,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +219,BTK,,10.1073/pnas.1803662115,1.1/37.4,87/80,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +220,BTK,,10.1073/pnas.1803662115,9.7/184.1,85/70,Degradation of BTK in Ramos/THP-1 cells after 24 h treatment, +221,BTK,,10.1038/s41589-020-00686-2,182,,Degradation of BTK in THP-1 cells, +221,BTK,45/49/64/85 (WB),10.1073/pnas.1803662115,,,,% BTK degradation in THP-1 cells after 24 h treatment at 0.1/0.3/1/3 μM +222,BTK,27/36/17/33/70 (WB),10.1073/pnas.1803662115,,,,% BTK degradation in THP-1 cells after 24 h treatment at 0.03/0.1/0.3/1/3 μM +223,ALK,,10.1016/j.ejmech.2018.03.071,3/34,,Degradation of NPM-ALK/EML4-ALK in SU-DHL-1/NCI-H2228 cells after 16 h treatment, +224,ALK,,10.1016/j.ejmech.2018.03.071,11/59,,Degradation of NPM-ALK/EML4-ALK in SU-DHL-1/NCI-H2228 cells after 16 h treatment, +225,HDAC6,,10.1016/j.bmcl.2018.05.057,,,, +226,HDAC6,,10.1016/j.bmcl.2018.05.057,,,, +227,HDAC6,47.9/73.5,10.1021/acs.jmedchem.9b00516,9.12,84.07,Degradation of HDAC6 in MM1S cells after 6 h treatment,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +227,HDAC6,,10.1016/j.bmcl.2018.05.057,34,70.5,Degradation of HDAC6 in MCF-7 cells after 12 h treatment, +228,HDAC6,,10.1016/j.bmcl.2018.05.057,,,, +229,BRD3,,10.1021/jacs.8b05807,10,,Degradation of BRD3 in HeLa cells after 24 h treatment, +229,BRD2,,10.1021/jacs.8b05807,10,,Degradation of BRD2 in HeLa cells after 24 h treatment, +229,BRD4,,10.1021/jacs.8b05807,1~3,,Degradation of BRD4 in HeLa cells after 24 h treatment, +230,BRD2,,10.1021/jacs.8b05807,3000,,Degradation of BRD2 in HeLa cells after 24 h treatment, +230,BRD3,,10.1021/jacs.8b05807,3000,,Degradation of BRD3 in HeLa cells after 24 h treatment, +230,BRD4,,10.1021/jacs.8b05807,10-30,,Degradation of BRD4 in HeLa cells after 24 h treatment, +231,BRD4,11/36/14 (WB),10.1016/j.ejmech.2019.01.023,,,,% BRD4 degradation in 22RV1 cells after 24 h treatment at 10/100/1000 nM +232,BRD4,13/12/21/63/56 (WB),10.1016/j.ejmech.2019.01.023,,,,% BRD4 degradation in 22RV1 cells after 24 h treatment at 0.1/1/10/100/1000 nM +233,BRD4,,10.1016/j.ejmech.2019.01.023,3.3,,Degradation of BRD4 in 22RV1 cells after 24 h treatment, +234,BRD4,,10.1016/j.ejmech.2019.01.023,0.32,,Degradation of BRD4 in 22RV1 cells after 24 h treatment, +235,BRAF,,10.1016/j.bioorg.2019.03.035,,,, +236,BRAF,71.7/81,10.1016/j.bioorg.2019.03.035,,,,% B-Raf degradation in MCF-7 cells after 24 h treatment at 5000/10000 nM +237,BRAF,,10.1016/j.bioorg.2019.03.035,,,, +238,BRAF,,10.1016/j.bioorg.2019.03.035,,,, +239,CDK4,,10.1002/anie.201901336,,,, +239,CDK6,,10.1016/j.bmcl.2020.127106,13,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +239,CDK6,,10.1021/acs.jmedchem.9b00871,14.3,,Degradation of CDK6 in U251 cells after 24 h treatment, +239,CDK4,,10.1016/j.bmcl.2020.127106,126,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +239,CDK4,,10.1016/j.chembiol.2018.11.006,,,, +239,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +239,Wee1,,10.1016/j.cell.2020.10.038,,,, +239,CDK6,,10.1002/anie.201901336,,,, +239,CDK6,,10.1016/j.chembiol.2018.11.006,,,, +240,PDK3,,10.1016/j.cell.2020.10.038,,,, +240,PDK1,,10.1016/j.cell.2020.10.038,,,, +240,BCKDK,,10.1016/j.cell.2020.10.038,,,, +240,CDK6,,10.1002/anie.201901336,,,, +240,CDK6,,10.1016/j.chembiol.2018.11.006,,,, +240,CDK4,,10.1016/j.cell.2020.10.038,,,, +240,Wee1,,10.1016/j.cell.2020.10.038,,,, +240,PDK2,,10.1016/j.cell.2020.10.038,,,, +240,COQ8A,,10.1016/j.cell.2020.10.038,,,, +241,BTK,,10.1038/s41422-018-0055-1,,,, +242,BTK C481S,41/69/78 (WB),10.1038/s41422-018-0055-1,,,,% BTK C481S degradation in HeLa cells after 4 days treatment at 30/100/300 nM +242,BTK,,10.1038/s41422-018-0055-1,8.5/6.3/9.2/11.4,,Degradation of BTK in RAMOS/HBL-1/Mino/IgE MM cells after 48 h treatment, +243,BTK,,10.1038/s41422-018-0055-1,,,, +244,BTK,,10.1038/s41422-018-0055-1,,,, +245,BTK,,10.1038/s41422-018-0055-1,,,, +246,BTK,,10.1038/s41422-018-0055-1,,,, +247,BTK,,10.1038/s41422-018-0055-1,,,, +248,BTK,,10.1038/s41422-018-0055-1,,,, +249,BTK,,10.1038/s41422-018-0055-1,,,, +250,BTK,,10.1038/s41422-018-0055-1,,,, +251,BTK,,10.1038/s41422-018-0055-1,,,, +252,BTK,,10.1038/s41422-018-0055-1,,,, +253,BTK,,10.1038/s41422-018-0055-1,,,, +254,BTK,,10.1038/s41422-018-0055-1,,,, +255,AR,,10.1038/s42003-018-0105-8,,47,, +256,AR,,10.1038/s42003-018-0105-8,15,76,Degradation of AR in VCaP cells after 20 h treatment, +257,AR,,10.1038/s42003-018-0105-8,5,98,Degradation of AR in VCaP cells after 20 h treatment, +258,BCL6,82 (WB),10.1021/acschembio.8b00698,,,,% BTK C481S degradation in OCI-Ly1 cells after 4 h treatment at 1 μM +259,ALK,,10.1016/j.bbrc.2018.09.169,,,, +260,ALK,,10.1016/j.bbrc.2018.09.169,,,, +261,ALK,,10.1016/j.bbrc.2018.09.169,,,, +262,ALK,,10.1016/j.bbrc.2018.09.169,,,, +263,ALK,,10.1016/j.bbrc.2018.09.169,,,, +264,ALK,,10.1016/j.bbrc.2018.09.169,,,, +265,FAK,,10.1021/jacs.8b08008,23.2,99,Degradation of Fak in PC3 cells after 24 h treatment, +266,FAK,,10.1021/jacs.8b08008,7.6,99,Degradation of Fak in PC3 cells after 24 h treatment, +267,FAK,,10.1021/jacs.8b08008,3,99,Degradation of Fak in PC3 cells after 24 h treatment, +268,FAK,,10.1021/jacs.8b08008,4,99,Degradation of Fak in PC3 cells after 24 h treatment, +269,FAK,,10.1021/jacs.8b08008,20.8,99,Degradation of Fak in PC3 cells after 24 h treatment, +270,FAK,,10.1021/jacs.8b08008,48.1,91,Degradation of Fak in PC3 cells after 24 h treatment, +271,FAK,,10.1021/jacs.8b08008,8.2,98,Degradation of Fak in PC3 cells after 24 h treatment, +272,FAK,,10.1021/jacs.8b08008,26.7,99,Degradation of Fak in PC3 cells after 24 h treatment, +273,FAK,,10.1021/jacs.8b08008,<10,87,Degradation of Fak in PC3 cells after 24 h treatment, +274,FLT3,,10.1021/jacs.8b10320,,,, +275,EGFR,,10.1016/j.chembiol.2017.09.009,39.2/736.2,97.6/68.8,Degradation of WT/Exon 20 Ins EGFR in OVCAR8/HeLa cells after 24 h treatment, +275,HER2,,10.1016/j.chembiol.2017.09.009,,,, +276,EGFR,,10.1016/j.chembiol.2017.09.009,11.7/22.3,98.9/96.6,Degradation of Exon 19 del/L858R EGFR in HCC827/H3255 cells after 24 h treatment, +277,EGFR,,10.1016/j.chembiol.2017.09.009,215.8,79.1,"Degradation of L858R, T790M EGFR in H1975 cells after 24 h treatment", +278,EGFR,,10.1016/j.chembiol.2017.09.009,,,, +279,MCL1,,10.1021/acs.jmedchem.9b00455,,,, +280,BTK,,10.1021/acs.biochem.8b00391,80.6,96,Degradation of BTK in NAMALWA cells after 24 h treatment, +281,BTK,,10.1021/acs.biochem.8b00391,90.1,93,Degradation of BTK in NAMALWA cells after 24 h treatment, +282,BTK,,10.1021/acs.biochem.8b00391,68.3,95,Degradation of BTK in NAMALWA cells after 24 h treatment, +283,BTK C481S,,10.1021/acs.biochem.8b00391,14.9,>99,Degradation of C481S BTK in XLA cells after 24 h treatment, +283,BTK,,10.1021/acs.biochem.8b00391,9.1/14.6,>99/(n/a),Degradation of BTK in NAMALWA/XLA cells after 24 h treatment, +283,BTK,,10.1016/j.bmcl.2019.126877,6.2,99,Degradation of BTK in NAMALWA cells after 24 h treatment, +284,BTK,,10.1021/acs.biochem.8b00391,11.6,>99,Degradation of BTK in NAMALWA cells after 24 h treatment, +285,RIPK2,,10.1016/j.chembiol.2017.09.010,,,, +285,MerTK,,10.1016/j.chembiol.2017.09.010,,,, +285,p38delta,,10.1016/j.chembiol.2017.09.010,27,91,Degradation of p38delta in MDA-MB-231 cells after 24 h treatment, +285,c-Met,,10.1016/j.chembiol.2017.09.010,,,, +286,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +287,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +288,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +289,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +290,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +291,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +292,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +293,CDK9,,10.1016/j.bioorg.2018.08.028,,,, +294,GCN5,,10.1021/acschembio.8b00705,<3,,Degradation of GCN5 in THP1 cells after 18 h treatment, +294,PCAF,,10.1021/acschembio.8b00705,<1.5,,Degradation of PCAF in THP1 cells after 18 h treatment, +295,PCAF,27/15/21/34/34 (WB),10.1021/acschembio.8b00705,,,,% PCAF degradation in THP1 cells after 18 h treatment at 0.1/1/10/100/1000 nM +296,CRBN,,10.1021/acschembio.8b00693,,,, +297,CRBN,,10.1021/acschembio.8b00693,,,, +298,CRBN,,10.1021/acschembio.8b00693,,,, +299,CRBN,,10.1021/acschembio.8b00693,,,, +300,CRBN,,10.1021/acschembio.8b00693,,,, +301,CRBN,,10.1021/acschembio.8b00693,,,, +302,CRBN,,10.1021/acschembio.8b00693,,,, +303,CDK9,56/65 (WB),10.1039/c7cc03879h,,,,% CDK9 degradation in HCT116 cells after 6 h treatment at 10/20 μM +304,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +305,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +306,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +307,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +308,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +309,PI3Kalpha,,10.1016/j.ejmech.2018.03.066,,,, +310,BRD4,,10.1021/acschembio.9b00092,,,, +310,BRD4,,10.1038/nchembio.2329,,,, +311,BRD4,,10.1038/nchembio.2329,,,, +312,BRD4,,10.1038/nchembio.2329,,,, +313,BRD4,,10.1038/nchembio.2329,,,, +314,BRD4,,10.1038/nchembio.2329,,,, +315,BRD4,,10.1038/nchembio.2329,,,, +316,BCR-ABL,,10.1002/anie.201507634,,,, +317,BCR-ABL,>90/>80 (WB),10.1002/anie.201507634,,,,% c-ABL/BCR-ABL degradation in K562 cells after 24 h treatment at 2.5 μM +318,BCR-ABL,,10.1002/anie.201507634,,,, +319,BCR-ABL,,10.1002/anie.201507634,,,, +320,BCR-ABL,,10.1002/anie.201507634,,,, +321,BCR-ABL,>65 (WB),10.1002/anie.201507634,,,,% c-ABL degradation in K562 cells after 24 h treatment at 1 μM +321,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +322,BCR-ABL,,10.1002/anie.201507634,,,, +323,BCR-ABL,,10.1002/anie.201507634,,,, +324,BCR-ABL,,10.1002/anie.201507634,,,, +325,BCR-ABL,>85/>60 (WB),10.1002/anie.201507634,,,,% c-ABL/BCR-ABL degradation in K562 cells after 24 h treatment at 1 μM +325,BCR-ABL,,10.1021/acs.jmedchem.0c00967,,,, +326,BCR-ABL,,10.1002/anie.201507634,,,, +327,BCR-ABL,,10.1002/anie.201507634,,,, +328,BRD3,,10.1073/pnas.1521738113,<5/<5/<5,,Degradation of BRD3 in 22Rv1/VCaP/LnCaP95 cells after 16 h treatment, +328,BRD4,,10.1073/pnas.1521738113,<5/<5/<5,,Degradation of BRD4 in 22Rv1/VCaP/LnCaP95 cells after 16 h treatment, +328,BRD2,,10.1073/pnas.1521738113,<5/<5/<5,,Degradation of BRD2 in 22Rv1/VCaP/LnCaP95 cells after 16 h treatment, +328,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +328,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +328,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +329,BRD4,,10.1016/j.chembiol.2015.05.009,<1/<1,,Degradation of BRD4 in Namalwa/CA-46 cells after overnight treatment, +329,BRD4,,10.1016/j.ejmech.2019.01.023,0.57,,Degradation of BRD4 in 22RV1 cells after 24 h treatment, +329,BRD4,,10.1021/acs.jmedchem.6b01912,0.6/1,97/100,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +329,BRD2,,10.1016/j.chembiol.2015.05.009,,,, +329,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +329,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +329,BRD3,,10.1016/j.chembiol.2015.05.009,,,, +329,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +329,BRD2,,10.1021/acs.jmedchem.6b01912,6,83,Degradation of BRD2 in HeLa cells after 24 h treatment, +329,BRD3,,10.1021/acs.jmedchem.6b01912,0.8,98,Degradation of BRD3 in HeLa cells after 24 h treatment, +330,BRD3,,10.1021/acs.jmedchem.8b00506,,,, +330,BRD4,,10.1021/acs.orglett.9b01326,,,, +330,BRD4,,10.1126/science.aab1433,430,,Degradation of BRD4 in SUM149 cells after 18 h treatment, +330,BRD4,,10.1038/s41589-018-0055-y,500/1000,,Degradation of BRD4 BD1/2 assessed by EGFP/mCherry reporter assay, +330,BRD4,,10.1002/anie.202108848,5.27/2.9,,Degradation of BRD4 in MV4-11 cells after 12/24 h treatment, +330,BRD4,,10.1002/anie.202108848,230,,Degradation of BRD4 in HD-MB03 cells after 12 h treatment, +330,BRD4,,10.1021/acs.jmedchem.8b00506,,,, +330,BRD2,,10.1021/acs.orglett.9b01326,,,, +330,BRD3,,10.1021/acs.orglett.9b01326,,,, +330,BRD2,,10.1126/science.aab1433,,,, +330,BRD3,,10.1126/science.aab1433,,,, +330,BRD2,,10.1021/acs.jmedchem.6b01816,,,, +330,BRD3,,10.1021/acs.jmedchem.6b01816,,,, +330,BRD4,,10.1021/acs.jmedchem.6b01816,,,, +330,BRD2,,10.1021/acs.jmedchem.8b00506,,,, +331,FKBP12,50/83/95/73 (WB),10.1126/science.aab1433,,,,% FKBP12 degradation in MV4;11 cells after 18 h treatment at 0.01/0.1/1/10 μM +332,FKBP12,60/81/93/74 (WB),10.1126/science.aab1433,,,,% FKBP12 degradation in MV4;11 cells after 18 h treatment at 0.01/0.1/1/10 μM +333,ERRalpha,,10.1038/nchembio.1858,100,86,Degradation of ERRalpha in MCF-7 cells after 8 h treatment, +334,RIPK2,,10.1038/nchembio.1858,1.4,95,Degradation of RIPK2 in THP-1 cells after 16 h treatment, +334,RIPK2,,10.1038/s42003-020-0868-6,2,,Degradation of RIPK2 in THP-1 cells after 18 h treatment, +335,BRD3,,10.1038/nchembio.2329,,,, +335,BRD2,,10.1038/nchembio.2329,,,, +335,BRD4,,10.1021/jacs.8b05807,,,, +335,BRD3,,10.1021/jacs.8b05807,,,, +335,BRD2,,10.1021/jacs.8b05807,,,, +335,BRD4,,10.1021/acschembio.5b00216,,,, +335,BRD3,,10.1021/acschembio.5b00216,,,, +335,BRD2,,10.1021/acschembio.5b00216,,,, +335,BRD3,,10.1038/s41589-019-0294-6,,,, +335,BRD3,,10.1021/acschembio.9b00092,,,, +335,BRD4,,10.1038/s41589-019-0294-6,,,, +335,BRD4,,10.1021/acschembio.9b00092,,,, +335,BRD2,,10.1021/acs.jmedchem.6b01912,40,98,Degradation of BRD2 in HeLa cells after 24 h treatment, +335,BRD2,,10.1038/s41589-019-0294-6,,,, +335,BRD4,,10.1038/nchembio.2329,,,, +335,BRD2,,10.1021/acschembio.9b00092,,,, +335,BRD4,,10.1021/acs.jmedchem.6b01912,8/3,98/100,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +335,BRD3,,10.1021/acs.jmedchem.6b01912,100,100,Degradation of BRD3 in HeLa cells after 24 h treatment, +336,BRD3,,10.1021/acs.jmedchem.6b01912,316,99,Degradation of BRD3 in HeLa cells after 24 h treatment, +336,BRD4,,10.1021/acs.jmedchem.6b01912,4/10,99/100,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +336,BRD2,,10.1021/acs.jmedchem.6b01912,200,97,Degradation of BRD2 in HeLa cells after 24 h treatment, +337,BRD2,,10.1021/acschembio.5b00216,,,, +337,BRD3,,10.1021/acschembio.5b00216,,,, +337,BRD4,,10.1021/acschembio.5b00216,,,, +338,AR,,10.1016/j.bmcl.2008.07.114,,,, +339,BRD3,,10.1038/s41589-018-0055-y,,,, +339,BRD4,,10.1038/s41589-018-0055-y,10/50,,Degradation of BRD4 BD1/2 assessed by EGFP/mCherry reporter assay, +339,BRD4,,10.1021/acschembio.1c00376,6,97,Degradation of BRD4 in HEK293T cells after 3 h treatment, +339,BRD2 BD2,,10.1038/s41589-018-0055-y,,,, +340,BRD4,,10.1038/s41589-018-0055-y,50/>1000,,Degradation of BRD4 BD1/2 assessed by EGFP/mCherry reporter assay, +341,BRD4,,10.1038/s41589-018-0055-y,,,, +342,BRD3 BD1,,10.1038/s41589-018-0055-y,,,, +342,BRD4 BD1,,10.1038/s41589-018-0055-y,500,,Degradation of BRD4 BD1 assessed by EGFP/mCherry reporter assay, +343,BRD4,,10.1038/s41589-018-0055-y,5/5,,Degradation of BRD4 BD1/2 assessed by EGFP/mCherry reporter assay, +344,BRD4,,10.1038/s41589-018-0055-y,,,, +345,BRD4 BD1,,10.1038/s41589-018-0055-y,,,, +346,BRD4,,10.1038/s41589-018-0055-y,,,, +347,BRD4,,10.1038/s41589-018-0055-y,,,, +348,BRD4 BD1,,10.1038/s41589-018-0055-y,,,, +349,BRD4 BD1,,10.1038/s41589-018-0055-y,,,, +350,BRD4 BD1,,10.1038/s41589-018-0055-y,5,,Degradation of BRD4 BD1 assessed by EGFP/mCherry reporter assay, +351,MCL1,,10.1021/acs.jmedchem.9b00455,,,, +352,MCL1,,10.1021/acs.jmedchem.9b00455,,,, +353,MCL1,,10.1021/acs.jmedchem.9b00455,,,, +354,AR,68/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +355,AR,81/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +356,AR,45/76/>95,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +357,AR,85/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +358,AR,92/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +359,AR,62/72/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +360,AR,8/11/17,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +361,AR,6/68/86,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +362,AR,21/67/68,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +363,AR,90/>95/>99,10.1021/acs.jmedchem.9b01393,0.5/1/0.2,>99/>95/>95,Degradation of AR in LNCaP/VCaP/22Rv1 cells after 6 h treatment,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +364,AR,48/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +365,AR,40/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +366,AR,38/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +367,AR,<5/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +368,AR,56/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +369,AR,62/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +370,AR,85/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +371,AR,31/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +372,AR,80/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +373,AR,76/>95/>99,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +374,AR,<5/<5/<5,10.1021/acs.jmedchem.9b01393,,,,% AR degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +375,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +375,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +376,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +376,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +377,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +377,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +378,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +378,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +379,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +379,CDK6,,10.1021/acs.jmedchem.9b00871,1.1,,Degradation of CDK6 in U251 cells after 24 h treatment, +380,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +380,CDK6,,10.1021/acs.jmedchem.9b00871,24.2,,Degradation of CDK6 in U251 cells after 24 h treatment, +381,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +381,CDK6,,10.1021/acs.jmedchem.9b00871,31,,Degradation of CDK6 in U251 cells after 24 h treatment, +382,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +382,CDK6,,10.1021/acs.jmedchem.9b00871,2.1,,Degradation of CDK6 in U251 cells after 24 h treatment, +383,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +383,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +384,CDK6,,10.1021/acs.jmedchem.9b00871,5.3,,Degradation of CDK6 in U251 cells after 24 h treatment, +384,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +385,CDK6,,10.1021/acs.jmedchem.9b00871,10.6,,Degradation of CDK6 in U251 cells after 24 h treatment, +385,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +386,CDK6,,10.1021/acs.jmedchem.9b00871,1.6,,Degradation of CDK6 in U251 cells after 24 h treatment, +386,CDK4,,10.1021/acs.jmedchem.9b00871,>50,,Degradation of CDK4 in U251 cells after 24 h treatment, +387,CDK6,,10.1021/acs.jmedchem.9b00871,1.7,,Degradation of CDK6 in U251 cells after 24 h treatment, +387,CDK4,,10.1021/acs.jmedchem.9b00871,>50,,Degradation of CDK4 in U251 cells after 24 h treatment, +388,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +388,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +389,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +389,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +390,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +390,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +391,CDK6,,10.1021/acs.jmedchem.9b00871,,,, +391,CDK4,,10.1021/acs.jmedchem.9b00871,,,, +392,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +392,CDK6,,10.1021/acs.jmedchem.9b00871,81.6,,Degradation of CDK6 in U251 cells after 24 h treatment, +393,CDK6,,10.1021/acs.jmedchem.9b00871,86.8,,Degradation of CDK6 in U251 cells after 24 h treatment, +393,CDK4,,10.1021/acs.jmedchem.9b00871,>100,,Degradation of CDK4 in U251 cells after 24 h treatment, +394,CDK4,,10.1021/acs.jmedchem.9b00871,>500,,Degradation of CDK4 in U251 cells after 24 h treatment, +394,CDK6,,10.1021/acs.jmedchem.9b00871,8.6,,Degradation of CDK6 in U251 cells after 24 h treatment, +395,CDK4,,10.1021/acs.jmedchem.9b00871,>500,,Degradation of CDK4 in U251 cells after 24 h treatment, +395,CDK6,,10.1021/acs.jmedchem.9b00871,129.7,,Degradation of CDK6 in U251 cells after 24 h treatment, +396,CDK6,,10.1021/acs.jmedchem.9b00871,271.9,,Degradation of CDK6 in U251 cells after 24 h treatment, +396,CDK4,,10.1021/acs.jmedchem.9b00871,>500,,Degradation of CDK4 in U251 cells after 24 h treatment, +397,CDK6,,10.1021/acs.jmedchem.9b00871,145.5,,Degradation of CDK6 in U251 cells after 24 h treatment, +397,CDK4,,10.1021/acs.jmedchem.9b00871,>500,,Degradation of CDK4 in U251 cells after 24 h treatment, +398,BTK,,10.1073/pnas.1803662115,,N.D.,, +399,BTK,,10.1073/pnas.1803662115,,N.D.,, +400,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +401,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +402,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +403,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +404,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +405,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +406,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +407,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +408,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +409,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +410,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +411,BCR-ABL,,10.1002/anie.201507634,,N.D.,, +412,BRD4,,10.1038/s41589-018-0055-y,,N.D.,, +412,BRD3,,10.1038/s41589-018-0055-y,,N.D.,, +412,BRD2,,10.1038/s41589-018-0055-y,,N.D.,, +413,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +413,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +414,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +414,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +415,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +415,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +416,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +416,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +417,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +417,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +418,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +418,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +419,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +419,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +420,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +420,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +421,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +421,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +422,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +422,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +423,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +423,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +424,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +424,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +425,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +425,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +426,CDK6,,10.1021/acs.jmedchem.9b00871,,N.D.,, +426,CDK4,,10.1021/acs.jmedchem.9b00871,,N.D.,, +427,MEK1,90/94,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +427,MEK2,,10.1021/acs.jmedchem.9b00810,,,, +428,MEK1,91/96,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +428,MEK2,,10.1021/acs.jmedchem.9b00810,,,, +429,MEK1,72/95,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +429,MEK2,,10.1021/acs.jmedchem.9b00810,,,, +430,MEK1,77/96,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +431,MEK1,47/94,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +432,MEK1,46/97,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +433,MEK1,18/48,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +434,MEK1,35/48,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +435,MEK1,67/91,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +436,MEK1,87/96,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +437,MEK1,16/39,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +438,MEK1,29/47,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +439,MEK1,3/38,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +440,MEK1,5/57,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +441,MEK1,30/65,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +442,MEK1,23/86,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +443,MEK1,8/57,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +444,MEK1,33/87,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +445,MEK1,41/88,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +446,MEK1,28/65,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +447,MEK1,45/47,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +448,MEK1,16/87,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +449,MEK1,57/93,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +450,MEK1,14/29,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +451,MEK1,30/81,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +452,MEK1,18/89,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +453,MEK1,42/94,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +454,MEK1,24/90,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +455,MEK1,55/96,10.1021/acs.jmedchem.9b00810,,,,% MEK1 degradation in A375 cells after 16 h treatment at 1000/10000 nM +456,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +457,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +458,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +459,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +460,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +461,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +462,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +463,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +464,BCR-ABL,,10.1021/acs.jmedchem.9b01264,10.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +465,BCR-ABL,,10.1021/acs.jmedchem.9b01264,37.9,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +466,BCR-ABL,,10.1021/acs.jmedchem.9b01264,8.5,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +467,BCR-ABL,,10.1021/acs.jmedchem.9b01264,17.9,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +468,BCR-ABL,,10.1021/acs.jmedchem.9b01264,34.7,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +469,BCR-ABL,,10.1021/acs.jmedchem.9b01264,40.2,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +470,BCR-ABL,,10.1021/acs.jmedchem.9b01264,611.4,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +471,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +472,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +473,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +474,BCR-ABL,0,10.1021/acs.jmedchem.9b01264,,,,% BCR-ABL degradation in K562 cells after 16 h treatment at 10000 nM +475,STAT3,,10.1021/acs.jmedchem.9b01530,2630,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +476,STAT3,,10.1021/acs.jmedchem.9b01530,260,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +477,STAT3,,10.1021/acs.jmedchem.9b01530,60/28,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +478,STAT3,,10.1021/acs.jmedchem.9b01530,90,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +479,STAT3,,10.1021/acs.jmedchem.9b01530,150,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +480,STAT3,,10.1021/acs.jmedchem.9b01530,650/919,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +481,STAT3,,10.1021/acs.jmedchem.9b01530,240/49,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +482,STAT3,,10.1021/acs.jmedchem.9b01530,50/11,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +483,STAT3,,10.1021/acs.jmedchem.9b01530,180,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +484,STAT3,,10.1021/acs.jmedchem.9b01530,250,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +485,STAT3,,10.1021/acs.jmedchem.9b01530,180,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +486,STAT3,,10.1021/acs.jmedchem.9b01530,2470,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +487,STAT3,,10.1021/acs.jmedchem.9b01530,380,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +488,STAT3,,10.1021/acs.jmedchem.9b01530,160,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +489,STAT3,,10.1021/acs.jmedchem.9b01530,90,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +490,STAT3,,10.1021/acs.jmedchem.9b01530,3540/>10000,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +491,STAT3,,10.1021/acs.jmedchem.9b01530,410,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +492,STAT3,,10.1021/acs.jmedchem.9b01530,360,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +493,STAT3,,10.1021/acs.jmedchem.9b01530,220/55,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +494,STAT3,,10.1021/acs.jmedchem.9b01530,640/890,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +495,STAT3,,10.1021/acs.jmedchem.9b01530,>10000,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +496,STAT3,,10.1021/acs.jmedchem.9b01530,>10000,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16 cells after 4 h treatment, +497,STAT3,,10.1021/acs.jmedchem.9b01530,4450/>10000,,Degradation of total STAT3 and p-STAT3Y705 proteins in Molm-16/SU-DHL-1 cells after 4/16 h treatment, +498,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +498,MCL1,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +499,MCL1,0/10 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +499,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +500,MCL1,,10.1021/acs.jmedchem.9b00919,700,,Degradation of MCL1 in HeLa cells after 12 h treatment, +500,BCL2,10/0/10/0/20 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 0.1/0.3/1/3/10 μM +501,BCL2,0/10 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +501,MCL1,0/10 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +502,MCL1,10 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 10 μM +502,BCL2,,10.1021/acs.jmedchem.9b00919,3000,,Degradation of BCL2 in HeLa cells after 12 h treatment, +503,MCL1,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +503,BCL2,10/10 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +504,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +504,MCL1,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +505,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +505,MCL1,10/20 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +506,MCL1,10/20 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +506,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +507,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +507,MCL1,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +508,BCL2,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% BCL2 degradation in HeLa cells after 12 h treatment at 1/10 μM +508,MCL1,0/0 (WB),10.1021/acs.jmedchem.9b00919,,,,% MCL1 degradation in HeLa cells after 12 h treatment at 1/10 μM +509,ALK,,10.1016/j.ejmech.2020.112190,,,, +510,ALK,,10.1016/j.ejmech.2020.112190,,,, +511,ALK,,10.1016/j.ejmech.2020.112190,,,, +512,ALK,,10.1016/j.ejmech.2020.112190,,,, +513,ALK,,10.1016/j.ejmech.2020.112190,>50,,Degradation of ALK in SR cells after 16 h treatment, +514,ALK,,10.1016/j.ejmech.2020.112190,15,,Degradation of ALK in SR cells after 16 h treatment, +515,ALK,,10.1016/j.ejmech.2020.112190,>50,,Degradation of ALK in SR cells after 16 h treatment, +516,ALK,,10.1016/j.ejmech.2020.112190,,,, +517,ALK,,10.1016/j.ejmech.2020.112190,,,, +518,ALK,,10.1016/j.ejmech.2020.112190,,,, +519,ALK,,10.1016/j.ejmech.2020.112190,,,, +520,ALK,,10.1016/j.ejmech.2020.112190,9.1,,Degradation of ALK in SR cells after 16 h treatment, +521,ALK,,10.1016/j.ejmech.2020.112190,20.9,,Degradation of ALK in SR cells after 16 h treatment, +522,ALK,,10.1016/j.ejmech.2020.112190,7.2,,Degradation of ALK in SR cells after 16 h treatment, +523,ALK,,10.1016/j.ejmech.2020.112190,7,,Degradation of ALK in SR cells after 16 h treatment, +523,ALK G1202R,,10.1016/j.ejmech.2020.112190,<200,,Degradation of G1202R ALK in 293T cells, +524,ALK,,10.1016/j.ejmech.2020.112190,,,, +525,ALK,,10.1016/j.ejmech.2020.112190,,,, +526,ALK,,10.1016/j.ejmech.2020.112190,,,, +527,ALK,,10.1016/j.ejmech.2020.112190,,,, +528,ALK,,10.1016/j.ejmech.2020.112190,11.4,,Degradation of ALK in SR cells after 16 h treatment, +529,ALK,,10.1016/j.ejmech.2020.112190,25.1,,Degradation of ALK in SR cells after 16 h treatment, +530,ALK,,10.1016/j.ejmech.2020.112190,7.5,,Degradation of ALK in SR cells after 16 h treatment, +531,ALK,,10.1016/j.ejmech.2020.112190,,,, +532,ALK,,10.1016/j.ejmech.2020.112190,,,, +533,ALK,,10.1016/j.ejmech.2020.112190,,,, +534,ALK,,10.1016/j.ejmech.2020.112190,,,, +535,ALK,,10.1016/j.ejmech.2020.112190,,,, +536,ALK,,10.1016/j.ejmech.2020.112190,,,, +537,ALK,,10.1016/j.ejmech.2020.112190,,,, +538,ALK,,10.1016/j.ejmech.2020.112190,,,, +539,ALK,,10.1016/j.ejmech.2020.112190,,,, +540,ALK,,10.1016/j.ejmech.2020.112190,,,, +541,ALK,,10.1016/j.ejmech.2020.112190,,,, +542,ALK,,10.1016/j.ejmech.2020.112190,,,, +543,AURKA,,10.1021/acs.jmedchem.7b01655,,,, +543,FAK,,10.1021/acs.jmedchem.7b01655,,,, +543,FER,,10.1021/acs.jmedchem.7b01655,,,, +543,RPS6KA1,,10.1021/acs.jmedchem.7b01655,,,, +543,ALK,,10.1021/acs.jmedchem.7b01655,10/180/50,,Degradation of ALK in H3122/Karpas 299/Kelly cells 16 h treatment, +544,AURKA,,10.1021/acs.jmedchem.7b01655,,,, +544,FAK,,10.1021/acs.jmedchem.7b01655,,,, +544,FER,,10.1021/acs.jmedchem.7b01655,,,, +544,RPS6KA1,,10.1021/acs.jmedchem.7b01655,,,, +544,ALK,,10.1021/acs.jmedchem.7b01655,10/40/50,,Degradation of ALK in H3122/Karpas 299/Kelly cells 16 h treatment, +545,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +546,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +547,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +548,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +549,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +550,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +551,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +552,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +553,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +554,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +555,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +556,MDM2,,10.1016/j.ejmech.2019.05.046,23,90,Degradation of MDM2 in RS4; 11 cells after 24 h treatment, +557,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +558,MDM2,,10.1016/j.ejmech.2019.05.046,,,, +559,EGFR,,10.1016/j.ejmech.2020.112061,45.2,87,Degradation of EGFR in HCC827 cells, +560,EGFR,,10.1016/j.ejmech.2020.112061,,,, +561,EGFR,,10.1016/j.ejmech.2020.112061,,,, +562,EGFR,,10.1016/j.ejmech.2020.112061,,,, +563,EGFR,,10.1016/j.ejmech.2020.112061,,,, +564,EGFR,,10.1016/j.ejmech.2020.112061,,,, +565,EGFR,,10.1016/j.ejmech.2020.112061,,,, +566,EGFR,,10.1016/j.ejmech.2020.112061,,,, +567,EGFR,,10.1016/j.ejmech.2020.112061,34.8,98,Degradation of EGFR in HCC827 cells, +568,EGFR,,10.1016/j.ejmech.2020.112061,,,, +569,EGFR,,10.1016/j.ejmech.2020.112061,,,, +570,EGFR,,10.1016/j.ejmech.2020.112061,,,, +571,EGFR,,10.1016/j.ejmech.2020.112061,,,, +572,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +572,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +573,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +573,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +574,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,263.8,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +574,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +575,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +575,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +576,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,312.9,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +576,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +577,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,25.3,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +577,EGFR,,10.1016/j.ejmech.2020.112199,50.3,,Degradation of EGFR in A431 cells after 16 h treatment, +578,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,77,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +578,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +579,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +579,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +580,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +580,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +581,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,69,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +581,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +582,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,235,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +582,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +583,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +583,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +584,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,132,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +584,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +585,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,466,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +585,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +586,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,5.9,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +586,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +587,EGFR,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR in A431 cells after 16 h treatment, +587,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112199,>2000,,Degradation of EGFR L858R/T790M in H1975 cells after 16h treatment, +588,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +588,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +589,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +589,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +590,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +590,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +591,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +591,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +592,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +592,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +593,EGFR L858R,,10.1021/acs.jmedchem.9b01566,3.3,,Degradation of EGFR L858R in H3255 cells after 16 h treatment, +593,EGFR e19d,,10.1021/acs.jmedchem.9b01566,5,,Degradation of EGFR e19d in HCC-827 cells after 16 h treatment, +594,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +594,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +595,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +595,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +596,EGFR L858R,,10.1021/acs.jmedchem.9b01566,,,, +596,EGFR e19d,,10.1021/acs.jmedchem.9b01566,,,, +597,EGFR e19d,,10.1021/acs.jmedchem.9b01566,11,,Degradation of EGFR e19d in HCC-827 cells after 16 h treatment, +597,EGFR L858R,,10.1021/acs.jmedchem.9b01566,25,,Degradation of EGFR L858R in H3255 cells after 16 h treatment, +598,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +598,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +599,CDK9,,10.1016/j.ejmech.2019.111952,,,, +599,CDK2,,10.1016/j.ejmech.2019.111952,,,, +600,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +600,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +601,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +601,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +602,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +602,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +603,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +603,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +604,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +604,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +605,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +605,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +606,CDK2,,10.1016/j.ejmech.2019.111952,,,, +606,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +607,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +607,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +608,CDK2,,10.1016/j.ejmech.2019.111952,,,, +608,CDK9,,10.1016/j.ejmech.2019.111952,,,, +609,CDK2,,10.1016/j.ejmech.2019.111952,,,, +609,CDK9,,10.1016/j.ejmech.2019.111952,,,, +610,CDK9,,10.1016/j.ejmech.2019.111952,33,,Degradation of CDK9 in PC-3 cells after 24 h treatment, +610,CDK2,,10.1016/j.ejmech.2019.111952,62,,Degradation of CDK2 in PC-3 cells after 24 h treatment, +611,CDK2,,10.1016/j.ejmech.2019.111952,,,, +611,CDK9,,10.1016/j.ejmech.2019.111952,,,, +612,CDK9,,10.1016/j.ejmech.2019.111952,,,, +612,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +613,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +613,CDK9,,10.1016/j.ejmech.2019.111952,,,, +614,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +614,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +615,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +615,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +616,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +616,CDK9,,10.1016/j.ejmech.2019.111952,,,, +617,CDK2,,10.1016/j.ejmech.2019.111952,,N.D.,, +617,CDK9,,10.1016/j.ejmech.2019.111952,,N.D.,, +618,BCL-xL,4 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +619,BCL-xL,8 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +620,BCL-xL,18 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +621,BCL-xL,48 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +622,BCL-xL,68 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +623,BCL-xL,39 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +624,BCL-xL,,10.1016/j.ejmech.2020.112186,93,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +625,BCL-xL,38 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +626,BCL-xL,22 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +627,BCL-xL,38 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +628,BCL-xL,21 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +629,BCL-xL,52 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +630,BCL-xL,28 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +631,BCL-xL,45 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +632,BCL-xL,22 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +633,BCL-xL,25 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +634,BCL-xL,40 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +635,BCL-xL,,10.1016/j.ejmech.2020.112186,71,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +636,BCL-xL,54 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +637,BCL-xL,51 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +638,BCL-xL,38 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +639,BCL-xL,76 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +640,BCL-xL,67 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +641,BCL-xL,67 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 100 nM +642,BCL-xL,56 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +643,BCL-xL,19 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +644,BCL-xL,37 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +645,BCL-xL,0 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +646,BCL-xL,11 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +647,BCL-xL,70 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +648,BCL-xL,80 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +649,BCL-xL,55 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +650,BCL-xL,80 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +651,BCL-xL,79 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +652,BCL-xL,89 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +653,BCL-xL,73 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +654,BCL-xL,24 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +655,BCL-xL,80 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +656,BCL-xL,87 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +657,BCL-xL,,10.1016/j.ejmech.2020.112186,4.5,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +658,BCL-xL,34 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +659,BCL-xL,33 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +660,BCL-xL,72 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +661,BCL-xL,71 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +662,BCL-xL,,10.1016/j.ejmech.2020.112186,6.3,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +663,BCL-xL,76 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +664,BCL-xL,,10.1016/j.ejmech.2020.112186,10.6,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +665,BCL-xL,60 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +666,BCL-xL,53 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +667,BCL-xL,27 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +668,BCL-xL,6 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +669,BCL-xL,89 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +670,BCL-xL,,10.1016/j.ejmech.2020.112186,2.5,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +671,BCL-xL,95 (WB),10.1016/j.ejmech.2020.112186,,,,% BCL-xL degradation in MOLT-4 cells after 16 h treatment at 50 nM +672,CYP1B1,,10.1016/j.ejmech.2019.112028,,,, +673,CYP1B1,,10.1016/j.ejmech.2019.112028,,,, +674,CYP1B1,,10.1016/j.ejmech.2019.112028,,,, +675,CYP1B1,,10.1016/j.ejmech.2019.112028,,,, +676,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +677,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +678,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +679,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +680,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +681,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +682,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +683,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +684,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +685,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +686,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +687,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +688,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +689,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +690,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +691,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +692,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +693,eIF4E,,10.1016/j.ejmech.2019.01.080,,,, +694,CRABP-II,,10.1021/ja100691p,,,, +694,CRABP-I,,10.1021/ja100691p,,,, +695,CRABP-II,,10.1021/ja100691p,,,, +695,CRABP-I,,10.1021/ja100691p,,,, +696,CRABP-I,,10.1021/ja100691p,,,, +696,CRABP-II,,10.1021/ja100691p,,,, +697,BCL-xL,,10.1038/s41591-019-0668-z,63/>3000,90.8/26,Degradation of BCL-xL in MOLT-4/platelets cells after 16 h treatment, +697,BCL-xL,,10.1016/j.ejmech.2020.112186,53,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +698,CDK4,,10.1002/anie.201901336,,,, +698,CDK6,,10.1002/anie.201901336,,,, +699,CDK4,,10.1002/anie.201901336,,,, +699,CDK6,,10.1002/anie.201901336,,,, +700,CDK6,,10.1182/blood.2019003604,,,, +700,CDK4,,10.1182/blood.2019003604,,,, +701,CDK6,,10.1016/j.bmcl.2020.127106,0.8,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +701,Wee1,,10.1016/j.cell.2020.10.038,,,, +701,CDK6,,10.1002/anie.201901336,,,, +701,CDK4,,10.1002/anie.201901336,,,, +701,CDK4,,10.1016/j.bmcl.2020.127106,10,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +702,CDK4,,10.1002/anie.201901336,,,, +702,PDK1,,10.1016/j.cell.2020.10.038,,,, +702,Wee1,,10.1016/j.cell.2020.10.038,,,, +702,CDK6,,10.1002/anie.201901336,,,, +703,CDK6,,10.1002/anie.201901336,,,, +703,CDK4,,10.1002/anie.201901336,,,, +704,CDK4,,10.1182/blood.2019003604,,,, +704,CDK6,,10.1002/anie.201901336,,,, +704,CDK6,,10.1182/blood.2019003604,,,, +704,CDK4,,10.1002/anie.201901336,,,, +705,CDK4,,10.1002/anie.201901336,,,, +705,CDK6,,10.1002/anie.201901336,,,, +706,CDK6,,10.1002/anie.201901336,,,, +706,CDK4,,10.1002/anie.201901336,,,, +707,CDK6,,10.1002/anie.201901336,,,, +707,CDK4,,10.1002/anie.201901336,,,, +708,CDK4,,10.1002/anie.201901336,,,, +708,CDK6,,10.1002/anie.201901336,,,, +709,COQ8A,,10.1016/j.cell.2020.10.038,,,, +709,PDK3,,10.1016/j.cell.2020.10.038,,,, +709,PDK2,,10.1016/j.cell.2020.10.038,,,, +709,PDK1,,10.1016/j.cell.2020.10.038,,,, +709,CDK6,,10.1016/j.cell.2020.10.038,,,, +709,BCKDK,,10.1016/j.cell.2020.10.038,,,, +709,CDK4,,10.1002/anie.201901336,,,, +710,CDK4,,10.1002/anie.201901336,,,, +710,CDK6,,10.1002/anie.201901336,,,, +711,CDK6,,10.1002/anie.201901336,,,, +711,CDK9,,10.1002/anie.201901336,,,, +711,CDK4,,10.1002/anie.201901336,,,, +712,PDEdelta,,10.1002/anie.201913904,,,, +713,PDEdelta,,10.1002/anie.201913904,,,, +714,PDEdelta,,10.1002/anie.201913904,48,83.4,Degradation of PDEdelta in Panc Tu-I cells after 24 h treatment, +715,PDEdelta,,10.1002/anie.201913904,,,, +716,BCL-xL,,10.1039/c9cc07217a,,,, +717,BCL-xL,,10.1039/c9cc07217a,50,,Degradation of BCL-xL in MOLT-4 cells after 16 h treatment, +718,BCL-xL,,10.1039/c9cc07217a,,,, +719,CDK4,,10.1039/c9cc00163h,12.9,,Degradation of CDK4 in MDA-MB-231 cells after 18 h treatment, +719,CDK6,,10.1039/c9cc00163h,34.1,,Degradation of CDK6 in MDA-MB-231 cells after 18 h treatment, +720,CDK6,,10.1039/c9cc00163h,,,, +720,CDK4,,10.1039/c9cc00163h,,,, +721,CDK6,,10.1039/c9cc00163h,300,,Degradation of CDK6 in MDA-MB-231 cells after 18 h treatment, +721,CDK4,,10.1039/c9cc00163h,97,,Degradation of CDK4 in MDA-MB-231 cells after 18 h treatment, +722,CDK4,,10.1039/c9cc00163h,,,, +722,CDK6,,10.1039/c9cc00163h,,,, +723,HDAC6,,10.1039/c9cc08509b,3.2,,Degradation of HDAC6 in MM.1S cells after 24 h treatment, +724,HDAC6,,10.1039/c9cc08509b,,,, +725,HDAC6,,10.1039/c9cc08509b,,,, +726,HDAC6,,10.1039/c9cc08509b,,,, +727,HDAC1,,10.1039/d0cc01485k,,,, +727,HDAC3,,10.1039/d0cc01485k,,,, +727,HDAC2,,10.1039/d0cc01485k,,,, +728,HDAC3,,10.1039/d0cc01485k,,,, +728,HDAC1,26/5/23/62 (WB),10.1039/d0cc01485k,,,,% HDAC1 degradation in HCT116 cells after 24 h treatment at 0.01/0.1/1/10 μM +728,HDAC2,10/0/0/40 (WB),10.1039/d0cc01485k,,,,% HDAC2 degradation in HCT116 cells after 24 h treatment at 0.01/0.1/1/10 μM +729,HDAC1,,10.1039/d0cc01485k,,,, +729,HDAC2,,10.1039/d0cc01485k,,,, +729,HDAC3,,10.1039/d0cc01485k,,,, +730,HDAC1,25/36/52/85 (WB),10.1039/d0cc01485k,,,,% HDAC1 degradation in HCT116 cells after 24 h treatment at 0.01/0.1/1/10 μM +730,HDAC2,21/22/60/76 (WB),10.1039/d0cc01485k,,,,% HDAC2 degradation in HCT116 cells after 24 h treatment at 0.01/0.1/1/10 μM +730,HDAC3,0/27/52/63 (WB),10.1039/d0cc01485k,,,,% HDAC3 degradation in HCT116 cells after 24 h treatment at 0.01/0.1/1/10 μM +731,RAR,,10.1016/j.bmc.2011.09.041,,,, +732,ER,,10.1016/j.bmc.2011.09.041,,,, +733,AR,,10.1016/j.bmc.2011.09.041,,,, +734,CRABP-II,,10.1016/j.bmc.2011.03.057,,,, +735,BRD4,,10.1016/j.bmc.2019.115181,,,, +736,BRD4,,10.1016/j.bmc.2019.115181,,,, +737,BRD3,,10.1016/j.bmc.2019.115181,,,, +737,BRD4,,10.1016/j.bmc.2019.115181,,,, +737,BRD2,,10.1016/j.bmc.2019.115181,,,, +738,BRD4,,10.1016/j.bmc.2019.115181,,,, +739,BRD4,,10.1016/j.bmc.2019.115181,,,, +740,CDK4,,10.1016/j.bmcl.2020.127106,25,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +740,CDK6,,10.1016/j.bmcl.2020.127106,4,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +741,CDK6,,10.1016/j.bmcl.2020.127106,20,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +741,CDK6,,10.1039/d0sc00167h,1.7,,Degradation of CDK6 in MM.1S cells after 16 h treatment, +741,CDK4,,10.1039/d0sc00167h,32,,Degradation of CDK4 in MM.1S cells after 16 h treatment, +741,CDK4,,10.1016/j.bmcl.2020.127106,631,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +742,CDK6,,10.1016/j.bmcl.2020.127106,200,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +742,CDK4,,10.1016/j.bmcl.2020.127106,2512,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +743,CDK6,,10.1016/j.bmcl.2020.127106,5,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +743,CDK4,,10.1016/j.bmcl.2020.127106,20,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +744,CDK4,,10.1016/j.bmcl.2020.127106,79,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +744,CDK6,,10.1016/j.bmcl.2020.127106,16,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +745,CDK6,,10.1016/j.bmcl.2020.127106,1585,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +745,CDK4,,10.1016/j.bmcl.2020.127106,5012,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +746,CDK6,,10.1016/j.bmcl.2020.127106,5,,Degradation of CDK6 in Jurkat cells after 24 h treatment, +746,CDK4,,10.1016/j.bmcl.2020.127106,50,,Degradation of CDK4 in Jurkat cells after 24 h treatment, +747,BCR-ABL,0/19 (WB),10.1016/j.bmcl.2016.09.041,,,,% BCR-ABL degradation in K562 cells after 24 h treatment at 30/100 μM +748,BCR-ABL,76/97 (WB),10.1016/j.bmcl.2016.09.041,,,,% BCR-ABL degradation in K562 cells after 24 h treatment at 30/100 μM +749,BCR-ABL,86/92 (WB),10.1016/j.bmcl.2016.09.041,,,,% BCR-ABL degradation in K562 cells after 24 h treatment at 30/100 μM +750,BTK,,10.1016/j.bmcl.2019.126877,374,49,Degradation of BTK in NAMALWA cells after 24 h treatment, +751,BTK,,10.1016/j.bmcl.2019.126877,162,50,Degradation of BTK in NAMALWA cells after 24 h treatment, +752,BTK,,10.1016/j.bmcl.2019.126877,>1000,,Degradation of BTK in NAMALWA cells after 24 h treatment, +753,BTK,,10.1016/j.bmcl.2019.126877,8.3,91,Degradation of BTK in NAMALWA cells after 24 h treatment, +754,BTK,,10.1016/j.bmcl.2019.126877,7.9,95,Degradation of BTK in NAMALWA cells after 24 h treatment, +755,JAK2,,10.1016/j.bmc.2020.115326,,,, +755,JAK1,,10.1016/j.bmc.2020.115326,,,, +756,JAK2,,10.1016/j.bmc.2020.115326,,,, +756,JAK1,,10.1016/j.bmc.2020.115326,,,, +757,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +757,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +758,JAK2,,10.1016/j.bmc.2020.115326,,,, +758,JAK1,,10.1016/j.bmc.2020.115326,,,, +759,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +759,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +760,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +760,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +761,JAK1,,10.1016/j.bmc.2020.115326,,,, +761,JAK2,,10.1016/j.bmc.2020.115326,,,, +762,JAK2,,10.1016/j.bmc.2020.115326,,,, +762,JAK1,,10.1016/j.bmc.2020.115326,,,, +763,JAK2,,10.1016/j.bmc.2020.115326,,,, +763,JAK1,,10.1016/j.bmc.2020.115326,,,, +764,JAK2,,10.1016/j.bmc.2020.115326,,,, +764,JAK1,,10.1016/j.bmc.2020.115326,,,, +765,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +765,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +766,JAK1,,10.1016/j.bmc.2020.115326,,,, +766,JAK2,,10.1016/j.bmc.2020.115326,,,, +767,JAK1,,10.1016/j.bmc.2020.115326,,,, +767,JAK2,,10.1016/j.bmc.2020.115326,,,, +768,JAK1,,10.1016/j.bmc.2020.115326,,,, +768,JAK2,,10.1016/j.bmc.2020.115326,,,, +769,JAK1,,10.1016/j.bmc.2020.115326,,,, +769,JAK2,,10.1016/j.bmc.2020.115326,,,, +770,JAK2,,10.1016/j.bmc.2020.115326,,,, +770,JAK1,,10.1016/j.bmc.2020.115326,,,, +771,JAK1,,10.1016/j.bmc.2020.115326,,,, +771,JAK2,,10.1016/j.bmc.2020.115326,,,, +772,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +772,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +773,JAK1,,10.1016/j.bmc.2020.115326,,,, +773,JAK2,,10.1016/j.bmc.2020.115326,,,, +774,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +774,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +775,JAK2,,10.1016/j.bmc.2020.115326,,N.D.,, +775,JAK1,,10.1016/j.bmc.2020.115326,,N.D.,, +776,JAK2,,10.1016/j.bmc.2020.115326,,,, +776,JAK1,,10.1016/j.bmc.2020.115326,,,, +777,JAK2,,10.1016/j.bmc.2020.115326,,,, +777,JAK1,,10.1016/j.bmc.2020.115326,,,, +778,JAK2,,10.1016/j.bmc.2020.115326,,,, +778,JAK1,,10.1016/j.bmc.2020.115326,,,, +779,BRD4,,10.1016/j.bmc.2019.115228,,,, +780,BRD4,,10.1016/j.bmc.2019.115228,,,, +781,BRD4,,10.1016/j.bmc.2019.115228,,,, +782,BRD4,,10.1016/j.bmc.2019.115228,,,, +783,BRD4,,10.1016/j.bmc.2019.115228,,,, +784,BRD4,,10.1016/j.bmc.2019.115228,,,, +785,BRD4,,10.1016/j.bmc.2019.115228,,,, +786,BRD4,,10.1016/j.bmc.2019.115228,,,, +787,BRD4,,10.1016/j.bmc.2019.115228,,,, +788,BRD4,,10.1016/j.bmc.2019.115228,,,, +789,BRD4,,10.1016/j.bmc.2019.115228,,,, +790,BRD4,,10.1016/j.bmc.2019.115228,,,, +791,BRD4,,10.1016/j.bmc.2019.115228,,,, +792,BRD4,,10.1016/j.bmc.2019.115228,,,, +793,BRD4,,10.1016/j.bmc.2019.115228,,,, +794,BRD4,,10.1016/j.bmc.2019.115228,,,, +795,BRD4,,10.1016/j.bmc.2019.115228,,,, +796,SMARCA2,,10.1038/s41589-019-0294-6,300,65,Degradation of SMARCA2 in MV-4-11 cells after 18 h treatment, +796,PBRM1,,10.1038/s41589-019-0294-6,,,, +796,SMARCA4,,10.1038/s41589-019-0294-6,250,70,Degradation of SMARCA4 in MV-4-11 cells after 18 h treatment, +797,SMARCA2,,10.1038/s41589-019-0294-6,,,, +797,PBRM1,,10.1038/s41589-019-0294-6,,,, +797,SMARCA4,,10.1038/s41589-019-0294-6,,,, +798,PBRM1,,10.1038/s41589-019-0294-6,32/15.6,,Degradation of PBRM1 in MV-4-11/NCI-H1568 cells after 18 h treatment, +798,SMARCA2,,10.1038/s41589-019-0294-6,6/3.3,,Degradation of SMARCA2 in MV-4-11/NCI-H1568 cells after 18 h treatment, +798,SMARCA4,,10.1038/s41589-019-0294-6,11,,Degradation of SMARCA2 in MV-4-11 cells after 18 h treatment, +799,CDK9,,10.1038/nchembio.2538,,,, +800,CDK9,,10.1038/nchembio.2538,,,, +801,CDK9,,10.1038/nchembio.2538,,,, +802,CDK9,,10.1038/nchembio.2538,,,, +803,CDK9,,10.1038/nchembio.2538,,,, +804,FKBP12,,10.1038/s41589-019-0279-5,,,, +805,FKBP12,,10.1038/s41589-019-0279-5,,,, +806,FKBP12,,10.1038/s41589-019-0279-5,,,, +807,FKBP12,,10.1038/s41589-019-0279-5,,,, +808,BRD4,,10.1038/s41589-019-0279-5,,,, +809,IRAK4,,10.1021/acsmedchemlett.9b00219,,N.D.,, +810,IRAK4,,10.1021/acsmedchemlett.9b00219,,50,, +811,IRAK4,,10.1021/acsmedchemlett.9b00219,,N.D.,, +812,IRAK4,,10.1021/acsmedchemlett.9b00219,,N.D.,, +813,IRAK4,,10.1021/acsmedchemlett.9b00219,,N.D.,, +814,IRAK4,,10.1021/acsmedchemlett.9b00219,,N.D.,, +815,IRAK4,,10.1021/acsmedchemlett.9b00219,259,,Degradation of IRAK4 in PBMC cells after 24 h treatment, +816,IRAK4,,10.1021/acsmedchemlett.9b00219,151/36,,Degradation of IRAK4 in PBMC cells/dermal fibroblast after 24/24 h treatment, +817,PLK1,,10.1016/j.bbrc.2019.11.007,10-20,,Degradation of PLK1 in MV4-11 cells after 24 h treatment, +817,BRD4,,10.1016/j.bbrc.2019.11.007,<5,,Degradation of BRD4 in MV4-11 cells after 24 h treatment, +818,BRD4,,10.1016/j.bbrc.2019.11.007,,,, +818,PLK1,,10.1016/j.bbrc.2019.11.007,,,, +819,CRABP-I,21/21/37/39/55 (WB),10.1021/acschembio.9b00704,,,,% CRABP-I degradation in IMR-32 cells after 24 h treatment at 0.1/0.3/1/3/10 μM +819,CRABP-II,7/42/48/54/55 (WB),10.1021/acschembio.9b00704,,,,% CRABP-II degradation in IMR-32 cells after 24 h treatment at 0.1/0.3/1/3/10 μM +820,CRABP-II,0/4/32 (WB),10.1021/acschembio.9b00704,,,,% CRABP-II degradation in IMR-32 cells after 24 h treatment at 0.1/1/10 μM +820,CRABP-I,3/20/35 (WB),10.1021/acschembio.9b00704,,,,% CRABP-I degradation in IMR-32 cells after 24 h treatment at 0.1/1/10 μM +821,CRABP-I,37/45/51/46/43 (WB),10.1021/acschembio.9b00704,,,,% CRABP-I degradation in IMR-32 cells after 8 h treatment at 0.3/1/3/10/30 μM +821,CRABP-II,29/48/52/47/35 (WB),10.1021/acschembio.9b00704,,,,% CRABP-II degradation in IMR-32 cells after 8 h treatment at 0.3/1/3/10/30 μM +822,BRD4,20/6/0/45 (WB),10.1021/acschembio.9b00704,,,,% BRD4 degradation in MCF7 cells after 24 h treatment at 0.01/0.1/1/10 μM +822,BRD2,6/1/4/34 (WB),10.1021/acschembio.9b00704,,,,% BRD2 degradation in MCF7 cells after 24 h treatment at 0.01/0.1/1/10 μM +822,BRD3,16/45/63/66 (WB),10.1021/acschembio.9b00704,,,,% BRD3 degradation in MCF7 cells after 24 h treatment at 0.01/0.1/1/10 μM +823,ER,,10.1021/acschembio.0c00140,,,, +824,ER,,10.1021/acschembio.0c00140,,,, +825,ER,,10.1021/acschembio.0c00140,7.7/10.3,95/98,Degradation of ERalpha in MCF-7/T47D cells after 6 h treatment, +826,ER,,10.1021/acschembio.0c00140,,,, +827,ER,,10.1021/acschembio.0c00140,,,, +828,ER,,10.1021/acschembio.0c00140,,,, +829,ER,,10.1021/acschembio.0c00140,,,, +830,ER,,10.1021/acschembio.0c00140,,,, +831,ER,,10.1021/acschembio.0c00140,,,, +832,ER,,10.1021/acschembio.0c00140,,,, +833,ER,,10.1021/acschembio.0c00140,,,, +834,ER,,10.1021/acschembio.0c00140,,,, +835,ER,,10.1021/acschembio.0c00140,,,, +836,ER,,10.1021/acschembio.0c00140,,,, +837,ER,,10.1021/acschembio.0c00140,,,, +838,ER,,10.1021/acschembio.0c00140,,,, +839,ER,,10.1021/acschembio.0c00140,,,, +840,ER,,10.1021/acschembio.0c00140,,,, +841,ER,,10.1021/acschembio.0c00140,,,, +842,ER,,10.1021/acschembio.0c00140,,,, +843,ER,,10.1021/acschembio.0c00140,,,, +844,ER,,10.1021/acschembio.0c00140,,,, +845,ER,,10.1021/acschembio.0c00140,,,, +846,ER,,10.1021/acschembio.0c00140,,,, +847,ER,,10.1021/acschembio.0c00140,,,, +848,ER,,10.1021/acschembio.0c00140,,,, +849,ER,,10.1021/acschembio.0c00140,,,, +850,ER,,10.1021/acschembio.0c00140,,,, +851,ER,,10.1021/acschembio.0c00140,,,, +852,ER,,10.1021/acschembio.0c00140,,,, +853,ER,,10.1021/acschembio.0c00140,,,, +854,ER,,10.1021/acschembio.0c00140,,,, +855,ER,,10.1021/acschembio.0c00140,,,, +856,ER,,10.1021/acschembio.0c00140,,,, +857,ER,,10.1021/acschembio.0c00140,,,, +858,ER,,10.1021/acschembio.0c00140,,,, +859,ER,,10.1021/acschembio.0c00140,,,, +860,ER,,10.1021/acschembio.0c00140,5.2,75,Degradation of ERalpha in MCF-7 cells after 6 h treatment, +861,ER,,10.1021/acschembio.0c00140,,,, +862,ER,,10.1021/acschembio.0c00140,,,, +863,ER,,10.1021/acschembio.0c00140,,,, +864,ER,,10.1021/acschembio.0c00140,,,, +865,ER,,10.1021/acschembio.0c00140,,,, +866,ER,,10.1021/acschembio.0c00140,,,, +867,ER,,10.1021/acschembio.0c00140,,,, +868,ER,,10.1021/acschembio.0c00140,,,, +869,ER,,10.1021/acschembio.0c00140,,,, +870,ER,,10.1021/acschembio.0c00140,,,, +871,ER,,10.1021/acschembio.0c00140,,,, +872,ER,,10.1021/acschembio.0c00140,,,, +873,ER,,10.1021/acschembio.0c00140,,,, +874,ER,,10.1021/acschembio.0c00140,,,, +875,ER,,10.1021/acschembio.0c00140,,,, +876,ER,,10.1021/acschembio.0c00140,,,, +877,ER,,10.1021/acschembio.0c00140,,,, +878,ER,,10.1021/acschembio.0c00140,,,, +879,ER,,10.1021/acschembio.0c00140,,,, +880,ER,,10.1021/acschembio.0c00140,,,, +881,ER,,10.1021/acschembio.0c00140,,,, +882,ER,,10.1021/acschembio.0c00140,,,, +883,ER,,10.1021/acschembio.0c00140,,,, +884,ER,,10.1021/acschembio.0c00140,,,, +885,ER,,10.1021/acschembio.0c00140,,,, +886,ER,,10.1021/acschembio.0c00140,,,, +887,ER,,10.1021/acschembio.0c00140,,,, +888,ER,,10.1021/acschembio.0c00140,,,, +889,ER,,10.1021/acschembio.0c00140,,,, +890,ER,,10.1021/acschembio.0c00140,,,, +891,ER,,10.1021/acschembio.0c00140,,,, +892,ER,,10.1021/acschembio.0c00140,,,, +893,ER,,10.1021/acschembio.0c00140,,,, +894,ER,,10.1021/acschembio.0c00140,,,, +895,ER,,10.1021/acschembio.0c00140,,,, +896,ER,,10.1021/acschembio.0c00140,,,, +897,ER,,10.1021/acschembio.0c00140,,,, +898,ER,,10.1021/acschembio.0c00140,,,, +899,ER,,10.1021/acschembio.0c00140,,,, +900,ER,,10.1021/acschembio.0c00140,,,, +901,ER,,10.1021/acschembio.0c00140,,,, +902,ER,,10.1021/acschembio.0c00140,,,, +903,ER,,10.1021/acschembio.0c00140,,,, +904,ER,,10.1021/acschembio.0c00140,,,, +905,ER,,10.1021/acschembio.0c00140,,,, +906,ER,,10.1021/acschembio.0c00140,,,, +907,ER,,10.1021/acschembio.0c00140,,,, +908,ER,,10.1021/acschembio.0c00140,,,, +909,ER,,10.1021/acschembio.0c00140,,,, +910,ER,,10.1021/acschembio.0c00140,,,, +911,ER,,10.1021/acschembio.0c00140,,,, +912,ER,,10.1021/acschembio.0c00140,,,, +913,ER,,10.1021/acschembio.0c00140,,,, +914,ER,,10.1021/acschembio.0c00140,,,, +915,ER,,10.1021/acschembio.0c00140,,,, +916,ER,,10.1021/acschembio.0c00140,,,, +917,ER,,10.1021/acschembio.0c00140,,,, +918,ER,,10.1021/acschembio.0c00140,,,, +919,ER,34/85/94 (WB),10.1021/acschembio.0c00140,,,,% ER degradation in MCF-7 cells after 6 h treatment at 10/100/1000 nM +920,ER,,10.1021/acschembio.0c00140,1.1,98,Degradation of ERalpha in MCF-7 cells after 6h treatment, +921,ER,28/85/94 (WB),10.1021/acschembio.0c00140,,,,% ER degradation in MCF-7 cells after 6 h treatment at 10/100/1000 nM +922,SGK3,23/59/77 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.1/1/10 μM +923,SGK3,0/3/16 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.1/1/10 μM +924,SGK3,19/26/30 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.1/1/10 μM +925,SGK3,0/11/16 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.1/1/10 μM +926,SGK3,18/8/27/64 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +927,SGK3,10/29/56/80 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +928,SGK3,20/5/63/71 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +929,SGK3,0/66/76/81 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +930,SGK3,29/60/89/88 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +931,SGK3,24/46/89/91 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +932,SGK3,3/59/68/71 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +933,SGK3,16/21/68/71 (WB),10.1021/acschembio.9b00505,,,,% SGK3 degradation in HEK293 cells after 48 h treatment at 0.01/0.1/1/10 μM +934,EED,,10.1016/j.chembiol.2019.11.004,,,, +934,EZH2,,10.1016/j.chembiol.2019.11.004,,,, +934,SUZ12,,10.1016/j.chembiol.2019.11.004,,,, +935,EED,,10.1016/j.chembiol.2019.11.004,,,, +935,SUZ12,,10.1016/j.chembiol.2019.11.004,,,, +935,EZH2,,10.1016/j.chembiol.2019.11.004,,,, +936,EED,,10.1016/j.chembiol.2019.11.006,,,, +936,SUZ12,,10.1016/j.chembiol.2019.11.006,,,, +936,EZH2,,10.1016/j.chembiol.2019.11.006,,,, +937,SUZ12,,10.1016/j.chembiol.2019.11.006,(n/a)/590,22/82,Degradation of SUZ12 in HeLa/DB cells after 24 h treatment, +937,EED,,10.1016/j.chembiol.2019.11.006,790/610,92/94,Degradation of EED in HeLa/DB cells after 24 h treatment, +937,EZH2,,10.1016/j.chembiol.2019.11.006,300/670,75/96,Degradation of EZH2 in HeLa/DB cells after 24 h treatment, +938,SUZ12,,10.1016/j.chembiol.2019.11.006,,,, +938,EZH2,,10.1016/j.chembiol.2019.11.006,,,, +938,EED,,10.1016/j.chembiol.2019.11.006,,,, +939,EED,,10.1016/j.chembiol.2019.11.006,,,, +939,SUZ12,,10.1016/j.chembiol.2019.11.006,,,, +939,EZH2,,10.1016/j.chembiol.2019.11.006,,,, +940,SUZ12,,10.1016/j.chembiol.2019.11.006,,,, +940,EED,,10.1016/j.chembiol.2019.11.006,,,, +940,EZH2,,10.1016/j.chembiol.2019.11.006,,,, +941,SUZ12,,10.1016/j.chembiol.2019.11.006,,,, +941,EZH2,,10.1016/j.chembiol.2019.11.006,,,, +941,EED,,10.1016/j.chembiol.2019.11.006,,,, +942,AKT1,,10.1016/j.chembiol.2019.11.014,,,, +942,MAPK6,,10.1016/j.cell.2020.10.038,,,, +942,STK17A,,10.1016/j.cell.2020.10.038,,,, +942,AKT2,,10.1016/j.chembiol.2019.11.014,,,, +942,AKT3,,10.1016/j.chembiol.2019.11.014,,,, +942,CDK4,,10.1016/j.cell.2020.10.038,,,, +943,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +944,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +945,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +946,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +947,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +948,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +949,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +950,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +951,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +952,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +953,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +954,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +955,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +956,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +957,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +958,KRAS G12C,,10.1016/j.chembiol.2019.12.006,,N.D.,, +959,BCR-ABL,,10.1158/0008-5472.CAN-19-1236,2000,85,Degradation of BCR-ABL in K562 cells after 18 h treatment, +960,BCR-ABL,,10.1158/0008-5472.CAN-19-1236,,,, +961,BCR-ABL,,10.1158/0008-5472.CAN-19-1236,340,95,Degradation of BCR-ABL in K562 cells after 18 h treatment, +962,CRBN,9 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +963,CRBN,9 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +964,CRBN,6 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +965,CRBN,14 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +966,CRBN,9 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +967,CRBN,35 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +968,CRBN,,10.1016/j.bmc.2019.02.048,200/230,75/98,Degradation of CRBN in HeLa/HEK293 cells, +969,CRBN,29 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +970,CRBN,54 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +971,CRBN,5 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +972,CRBN,29 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +973,CRBN,32 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +974,CRBN,19 (WB),10.1016/j.bmc.2019.02.048,,,,% CRBN degradation in HeLa cells after 4 h treatment at 1 μM +975,FKBP12,,10.1038/s41421-018-0079-1,0.27,,Degradation of FKBP12 in Jurkat cells after 12 h treatment, +976,BTK,,10.1038/s41421-018-0079-1,,,, +977,RIPK2,,10.1038/s42003-020-0868-6,0.4,,Degradation of RIPK2 in THP-1 cells after 18 h treatment, +978,RIPK2,,10.1038/s42003-020-0868-6,2.5,,Degradation of RIPK2 in THP-1 cells after 18 h treatment, +979,RIPK2,,10.1038/s42003-020-0868-6,12.6,69.2,Degradation of RIPK2 in hPBMC cells after 24 h treatment, +979,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +980,RIPK2,,10.1021/acs.jmedchem.1c01118,0.79,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +980,RIPK2,,10.1038/s42003-020-0868-6,0.4,94.3,Degradation of RIPK2 in hPBMC cells after 24 h treatment, +981,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +982,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +983,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +984,Cdc20,,10.1016/j.ebiom.2019.10.013,1600/1600,,Degradation of Cdc20 in MCF7/MDA-MB-231 cells after 10 h treatment, +985,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +986,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +987,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +988,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +989,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +990,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +991,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +992,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +993,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +994,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +995,Cdc20,,10.1016/j.ebiom.2019.10.013,,,, +996,VHL,88/96 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30 degradation in HeLa cells after 24 h treatment at 1/10 μM +997,VHL,36/38/87/100/100 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30 degradation in HeLa cells after 24 h treatment at 0.001/0.01/0.1/1/10 μM +998,VHL,,10.1038/s41467-017-00954-1,10-100,,Degradation of pVHL30 in HeLa cells after 24 h treatment, +999,VHL,0/7 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30/pVHL19 degradation in HeLa cells after 10 h treatment at 1 μM +1000,VHL,0/3 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30/pVHL19 degradation in HeLa cells after 10 h treatment at 1 μM +1001,VHL,0/11 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30/pVHL19 degradation in HeLa cells after 10 h treatment at 1 μM +1002,VHL,0/0 (WB),10.1038/s41467-017-00954-1,,,,% pVHL30/pVHL19 degradation in HeLa cells after 10 h treatment at 1 μM +1003,TRKC,,10.1021/acs.molpharmaceut.9b00673,100-1000,,Degradation of TrkC in Hs578t cells after 24 h treatment, +1004,TRKC,,10.1021/acs.molpharmaceut.9b00673,,,, +1005,TRKC,,10.1021/acs.molpharmaceut.9b00673,,,, +1006,CRABP-II,,10.1016/j.bmcl.2012.04.134,,,, +1007,HDAC6,,10.1007/s13238-018-0602-z,,,, +1008,HDAC6,,10.1007/s13238-018-0602-z,3.8,,Degradation of HADC6 in MM.1S cells after 24 h treatment, +1009,HDAC6,,10.1007/s13238-018-0602-z,,,, +1010,HDAC6,,10.1007/s13238-018-0602-z,,,, +1011,CRBN,,10.1038/s41598-019-56177-5,44.5,97.1,Degradation of CRBN in HEK293T cells after 24h treatment, +1012,CRBN,,10.1038/s41598-019-56177-5,20.4,99.6,Degradation of CRBN in HEK293T cells after 24h treatment, +1013,CRBN,,10.1038/s41598-019-56177-5,100.6,96.9,Degradation of CRBN in HEK293T cells after 24h treatment, +1014,CRBN,,10.1038/s41598-019-56177-5,28.8,98.4,Degradation of CRBN in HEK293T cells after 24h treatment, +1015,CRBN,,10.1038/s41598-019-56177-5,367.7,82,Degradation of CRBN in HEK293T cells after 24h treatment, +1016,CRBN,,10.1038/s41598-019-56177-5,2546.1,77.9,Degradation of CRBN in HEK293T cells after 24h treatment, +1017,BCR-ABL,,10.1111/cas.13284,100000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1018,BCR-ABL,,10.1111/cas.13284,20000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1019,BCR-ABL,,10.1111/cas.13284,10000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1020,BCR-ABL,,10.1111/cas.13284,>100000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1021,BCR-ABL,,10.1111/cas.13284,>100000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1022,BCR-ABL,,10.1111/cas.13284,5000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1023,BCR-ABL,,10.1111/cas.13284,2000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1024,BCR-ABL,,10.1111/cas.13284,300,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1025,BCR-ABL,,10.1111/cas.13284,10000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1026,BCR-ABL,,10.1111/cas.13284,5000,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1027,BCR-ABL,,10.1111/cas.13284,300,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1028,BCR-ABL,,10.1111/cas.13284,10,,Degradation of BCR-ABL in K562 cells after 6 h treatment, +1029,BCR-ABL,19/39 (WB),10.1111/cas.13284,,,,% BCR-ABL degradation in K562 cells after 6 h treatment at 10/30 nM +1030,BCR-ABL,11/46 (WB),10.1111/cas.13284,,,,% BCR-ABL degradation in K562 cells after 6 h treatment at 10/30 nM +1031,BCR-ABL,39/65 (WB),10.1111/cas.13284,,,,% BCR-ABL degradation in K562 cells after 6 h treatment at 10/30 nM +1032,BCR-ABL,36/18/19/95 (WB),10.1021/acsmedchemlett.7b00247,,,,% BCR-ABL degradation in K562 cells after 6 h treatment at 10/100/1000/5000 nM +1033,BCR-ABL,28/46/62/72/48 (WB),10.1021/acsmedchemlett.7b00247,,,,% BCR-ABL degradation in K562 cells after 6 h treatment at 10/30/100/300/1000 nM +1034,ER,,10.1016/j.bmcl.2011.11.086,,,, +1035,ER,,10.1016/j.bmcl.2011.11.086,,,, +1036,ER,,10.1016/j.bmcl.2011.11.086,,,, +1037,ER,0/5/13/32 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 24 h treatment at 3/10/30/100 nM +1038,ER,,10.1074/jbc.M116.768853,3,,Degradation of ERalpha in MCF-7 cells after 6 h treatment, +1038,ER,,10.1074/jbc.RA117.001091,<3/83,,Degradation of ERalpha in MCF-7 cells after 4/48 h treatment, +1039,ER,18/40/53/54 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 24 h treatment at 3/10/30/100 nM +1040,BRD4,,10.1248/cpb.c18-00567,,,, +1040,BRD4,67/74/30 (WB),10.1074/jbc.M116.768853,,,,% BRD4 degradation in LNCaP cells after 6 h treatment at 10/100/1000 nM +1041,PDE4,62/61/67/43 (WB),10.1074/jbc.M116.768853,,,,% PDE4 degradation in HT1080 cells after 6 h treatment at 1/10/100/1000 nM +1042,ER,0/0/0/13 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.01/0.1/1/10 μM +1043,ER,0 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.03/0.1/0.3/1 μM +1044,ER,56/65/67/64 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.03/0.1/0.3/1 μM +1045,ER,36/61/53/57 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.01/0.1/1/10 μM +1046,ER,49/52/53/44 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.03/0.1/0.3/1 μM +1047,ER,0/16/36/18 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.01/0.1/1/10 μM +1048,ER,8/43/5/42 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.01/0.1/1/10 μM +1049,ER,0 (WB),10.1074/jbc.M116.768853,,,,% ERalpha degradation in MCF-7 cells after 6 h treatment at 0.01/0.1/1/10 μM +1050,BRD4,56/67/34/18 (WB),10.1248/cpb.c18-00567,,,,% BRD4 degradation in LNCaP cells after 6 h treatment at 0.01/0.1/1/10 μM +1051,ER,,10.1074/jbc.RA117.001091,>100,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1052,ER,,10.1074/jbc.RA117.001091,<3/<3,,Degradation of ERalpha in MCF-7 cells after 4/48h treatment, +1053,ER,,10.1074/jbc.RA117.001091,<3/7.7,,Degradation of ERalpha in MCF-7 cells after 4/48h treatment, +1054,ER,,10.1074/jbc.RA117.001091,<3/13.3,,Degradation of ERalpha in MCF-7 cells after 4/48h treatment, +1055,ER,,10.1074/jbc.RA117.001091,>100,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1056,ER,,10.1074/jbc.RA117.001091,4/15.7,,Degradation of ERalpha in MCF-7 cells after 4/48h treatment, +1057,ER,,10.1074/jbc.RA117.001091,>100,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1058,ER,,10.1074/jbc.RA117.001091,<3/3.7,,Degradation of ERalpha in MCF-7 cells after 4/48h treatment, +1059,ER,,10.1074/jbc.RA117.001091,36.9,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1060,ER,,10.1074/jbc.RA117.001091,33.8,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1061,ER,,10.1074/jbc.RA117.001091,>100,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1062,ER,,10.1074/jbc.RA117.001091,>100,,Degradation of ERalpha in MCF-7 cells after 4h treatment, +1063,AR,,10.1021/acs.jmedchem.7b00168,21600,,Degradation of AR in 22Rv1 cells after 6 h treatment, +1064,AR,,10.1021/acs.jmedchem.7b00168,>30000,,Degradation of AR in 22Rv1 cells after 6 h treatment, +1065,AR,,10.1021/acs.jmedchem.7b00168,11700,,Degradation of AR in 22Rv1 cells after 6 h treatment, +1066,AR,,10.1021/acs.jmedchem.7b00168,20500,,Degradation of AR in 22Rv1 cells after 6 h treatment, +1067,AR,,10.1021/acs.jmedchem.7b00168,>30000,,Degradation of AR in 22Rv1 cells after 6 h treatment, +1068,AR,0/40/52 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 3/10/20 μM +1069,AR,57/62/52 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 3/10/30 μM +1070,AR,24/74 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1071,AR,8/73 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1072,AR,32/74 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1073,AR,10/94 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1074,AR,21/86 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1075,AR,23/89 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1076,AR,0/18 (WB),10.1021/acs.jmedchem.7b00168,,,,% AR degradation in 22Rv1 cells after 6 h treatment at 1/3 μM +1077,AR,,10.1021/acs.jmedchem.7b00168,,N.D.,, +1078,AR,,10.1021/acs.jmedchem.7b00168,,N.D.,, +1079,AR,,10.1021/acs.jmedchem.7b00168,,N.D.,, +1080,BRAF V600E,88 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1081,BRAF V600E,91 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1081,BRAF V600E,,10.1038/s41589-020-0609-7,100,65,Degradation of BRAF V600E in A375 cells after 24 h treatment, +1082,BRAF V600E,84 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1083,BRAF V600E,49 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1084,BRAF V600E,36 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1085,BRAF V600E,21 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1086,BRAF V600E,14 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1087,BRAF V600E,33 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1088,BRAF V600E,36 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1089,BRAF V600E,53 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1090,BRAF V600E,56 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1091,BRAF V600E,6 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1092,BRAF V600E,7 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1093,BRAF V600E,11 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1094,BRAF V600E,12 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1095,BRAF V600E,11 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1096,BRAF V600E,16 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1097,BRAF V600E,59 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1098,BRAF V600E,,10.1038/s41589-020-0609-7,15,82,Degradation of BRAF V600E in A375 cells after 24 h treatment, +1098,BRAF V600E,93 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1099,BRAF V600E,95 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1099,BRAF V600E,,10.1038/s41589-020-0609-7,70,82,Degradation of BRAF V600E in A375 cells after 24 h treatment, +1100,BRAF V600E,36 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1101,BRAF V600E,16 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1102,BRAF V600E,41 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1103,BRAF V600E,33 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1104,BRAF V600E,17 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1105,BRAF V600E,24 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1106,BRAF V600E,36 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1106,BRAF V600E,,10.1038/s41589-020-0609-7,100,40,Degradation of BRAF V600E in A375 cells after 24 h treatment, +1107,BRAF V600E,54 (WB),10.1021/acs.jmedchem.9b02083,,,,% BRAF V600 degradation in A375 cells after 16 h treatment at 500 nM +1108,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1109,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1110,HMGCR,,10.1021/acs.jmedchem.0c00339,3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1111,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1112,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1113,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1114,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1115,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1116,HMGCR,,10.1021/acs.jmedchem.0c00339,1800,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1117,HMGCR,,10.1021/acs.jmedchem.0c00339,100,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1118,HMGCR,,10.1021/acs.jmedchem.0c00339,400,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1119,HMGCR,,10.1021/acs.jmedchem.0c00339,500,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1120,HMGCR,,10.1021/acs.jmedchem.0c00339,200,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1121,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1122,HMGCR,,10.1021/acs.jmedchem.0c00339,600,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1123,HMGCR,,10.1021/acs.jmedchem.0c00339,,,, +1124,HMGCR,,10.1021/acs.jmedchem.0c00339,400,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1125,HMGCR,,10.1021/acs.jmedchem.0c00339,200,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1126,HMGCR,,10.1021/acs.jmedchem.0c00339,300,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1127,HMGCR,,10.1021/acs.jmedchem.0c00339,400,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1128,HMGCR,,10.1021/acs.jmedchem.0c00339,300,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1129,HMGCR,,10.1021/acs.jmedchem.0c00339,500,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1130,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1131,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1132,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1133,HMGCR,,10.1021/acs.jmedchem.0c00339,300,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1134,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1135,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1136,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1137,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1138,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1139,HMGCR,,10.1021/acs.jmedchem.0c00339,300,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1140,HMGCR,,10.1021/acs.jmedchem.0c00339,200,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1141,HMGCR,,10.1021/acs.jmedchem.0c00339,700,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1142,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1143,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1144,HMGCR,,10.1021/acs.jmedchem.0c00339,>3000,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1145,HMGCR,,10.1021/acs.jmedchem.0c00339,2300,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1146,HMGCR,,10.1021/acs.jmedchem.0c00339,500,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1147,HMGCR,,10.1021/acs.jmedchem.0c00339,600,,Degradation of HMGCR in SRD15 cells after 16 h treatment, +1148,MEK2,,10.1021/acs.jmedchem.9b01528,,,, +1148,MEK1,,10.1021/acs.jmedchem.9b01528,,,, +1149,MEK1,,10.1021/acs.jmedchem.9b01528,,,, +1149,MEK2,,10.1021/acs.jmedchem.9b01528,,,, +1150,MEK1,,10.1021/acs.jmedchem.9b01528,,,, +1150,MEK2,,10.1021/acs.jmedchem.9b01528,,,, +1151,MEK2,,10.1021/acs.jmedchem.9b01528,,,, +1151,MEK1,,10.1021/acs.jmedchem.9b01528,,,, +1152,MEK1,,10.1021/acs.jmedchem.9b01528,,,, +1152,MEK2,,10.1021/acs.jmedchem.9b01528,,,, +1153,MEK1,,10.1021/acs.jmedchem.9b01528,31/31/18,,Degradation of MEK1 in HT-29/SK-MEL-28/COLO 205 cells after 24 h treatment, +1153,MEK2,,10.1021/acs.jmedchem.9b01528,17/9.3/11,,Degradation of MEK2 in HT-29/SK-MEL-28/COLO 205 cells after 24 h treatment, +1154,HDAC6,62.1/81.3,10.1021/acs.jmedchem.9b00516,3.41,88.01,Degradation of HDAC6 in MM1S cells after 6 h treatment,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1155,HDAC6,67.3/84.1,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1156,HDAC6,64.3/85,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1157,HDAC6,,10.1021/acsmedchemlett.0c00046,2.2/18,86/45,Degradation of HDAC6 in MM1S/Mouse 4935 cells after 4/6 h treatment, +1157,HDAC6,74.9/82.7,10.1021/acs.jmedchem.9b00516,1.64,86.26,Degradation of HDAC6 in MM1S cells after 6 h treatment,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1158,HDAC6,66.1/77.8,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1159,HDAC6,49.3/81.8,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1160,HDAC6,64.8/84.2,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1161,HDAC6,71.7/79.2,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1162,HDAC6,70.6/83.1,10.1021/acs.jmedchem.9b00516,2.54,86.3,Degradation of HDAC6 in MM1S cells after 6 h treatment,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1163,HDAC6,45.6/77.3,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1164,HDAC6,50.9/75.7,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1165,HDAC6,57.1/81.4,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1166,HDAC6,60.3/81.2,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1167,HDAC6,63.3/80.9,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1168,HDAC6,69.9/84.7,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1169,HDAC6,70.8/83.5,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1170,HDAC6,47.2/80.4,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1171,HDAC6,60.9/81.9,10.1021/acs.jmedchem.9b00516,,,,% HDAC6 degradation in MM1S cells after 6 h treatment at 10/100 nM +1172,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1173,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1174,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1175,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1176,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1177,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1178,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1179,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1180,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1181,HDAC6,,10.1021/acsmedchemlett.0c00046,7.1/4.3,90/57,Degradation of HDAC6 in MM1S/Mouse 4935 cells after 4/6 h treatment, +1182,HDAC6,,10.1021/acsmedchemlett.0c00046,11,89,Degradation of HDAC6 in MM1S cells after 4 h treatment, +1183,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1184,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1185,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1186,HDAC6,,10.1021/acsmedchemlett.0c00046,,,, +1187,BRD9,,10.1002/anie.201611281,,,, +1188,BRD9,,10.1002/anie.201611281,,,, +1189,BRD9,,10.1002/anie.201611281,,,, +1190,BRD9,,10.1002/anie.201611281,,,, +1191,BRD9,,10.1002/anie.201611281,,,, +1192,BRD9,,10.1002/anie.201611281,,,, +1193,BRD9,,10.1002/anie.201611281,,,, +1194,BRD9,,10.1002/anie.201611281,,,, +1195,BRD9,,10.1002/anie.201611281,,,, +1196,BRD7,,10.1002/anie.201611281,,,, +1196,BRD4,,10.1002/anie.201611281,,,, +1196,BRD9,,10.1002/anie.201611281,,,, +1197,BRD9,,10.1002/anie.201611281,,,, +1198,BRD9,,10.1002/anie.201611281,,,, +1199,BRD9,,10.1002/anie.201611281,,,, +1200,BRD9,,10.1002/anie.201611281,,,, +1201,BRD9,,10.1021/acs.jmedchem.8b01413,,,, +1201,BRD9,,10.1002/anie.201611281,,,, +1202,Htt,,10.1002/anie.201706529,,,, +1203,Htt,,10.1002/anie.201706529,,,, +1204,CDK2,,10.1002/anie.202004087,,,, +1205,CDK2,,10.1002/anie.202004087,,,, +1206,CDK2,,10.1002/anie.202004087,,,, +1207,CDK2,,10.1002/anie.202004087,,,, +1208,CDK2,,10.1002/anie.202004087,,,, +1209,CDK2,,10.1002/anie.202004087,,,, +1210,CDK6,,10.1002/anie.202004087,,,, +1210,CDK4,,10.1002/anie.202004087,,,, +1210,CDK12,,10.1016/j.cell.2020.10.038,,,, +1210,CDK2,,10.1002/anie.202004087,,,, +1210,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +1210,CDK17,,10.1016/j.cell.2020.10.038,,,, +1210,CDK16,,10.1016/j.cell.2020.10.038,,,, +1210,CDK5,,10.1002/anie.202004087,,,, +1210,CDK9,,10.1016/j.cell.2020.10.038,,,, +1210,CDK7,,10.1016/j.cell.2020.10.038,,,, +1210,MAPK9,,10.1016/j.cell.2020.10.038,,,, +1210,MAPK8,,10.1016/j.cell.2020.10.038,,,, +1210,CDK1,,10.1016/j.cell.2020.10.038,,,, +1210,AURKA,,10.1016/j.cell.2020.10.038,,,, +1210,MAPK10,,10.1016/j.cell.2020.10.038,,,, +1211,CDK16,,10.1016/j.cell.2020.10.038,,,, +1211,PRKAA1,,10.1016/j.cell.2020.10.038,,,, +1211,PTK2B,,10.1016/j.cell.2020.10.038,,,, +1211,STK38,,10.1016/j.cell.2020.10.038,,,, +1211,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +1211,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +1211,AAK1,,10.1016/j.cell.2020.10.038,,,, +1211,AURKB,,10.1016/j.cell.2020.10.038,,,, +1211,STK33,,10.1016/j.cell.2020.10.038,,,, +1211,CDK12,,10.1016/j.cell.2020.10.038,,,, +1211,IRAK3,,10.1016/j.cell.2020.10.038,,,, +1211,TTK,,10.1016/j.cell.2020.10.038,,,, +1211,MAPK8,,10.1016/j.cell.2020.10.038,,,, +1211,MAPK9,,10.1016/j.cell.2020.10.038,,,, +1211,CLK1,,10.1016/j.cell.2020.10.038,,,, +1211,GSK3A,,10.1016/j.cell.2020.10.038,,,, +1211,GSK-3beta,,10.1016/j.cell.2020.10.038,,,, +1211,CDK7,,10.1016/j.cell.2020.10.038,,,, +1211,CDK9,,10.1016/j.cell.2020.10.038,,,, +1211,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +1211,PRKAA2,,10.1016/j.cell.2020.10.038,,,, +1211,CDK5,,10.1016/j.cell.2020.10.038,,,, +1211,CDK17,,10.1016/j.cell.2020.10.038,,,, +1211,CDK2,,10.1002/anie.202004087,,,, +1211,AURKA,,10.1016/j.cell.2020.10.038,,,, +1211,NUAK1,,10.1016/j.cell.2020.10.038,,,, +1211,CDK1,,10.1016/j.cell.2020.10.038,,,, +1211,FER,,10.1016/j.cell.2020.10.038,,,, +1212,STK33,,10.1016/j.cell.2020.10.038,,,, +1212,AURKB,,10.1016/j.cell.2020.10.038,,,, +1212,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +1212,FAK,,10.1016/j.cell.2020.10.038,,,, +1212,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +1212,MAPK9,,10.1016/j.cell.2020.10.038,,,, +1212,MAPK8,,10.1016/j.cell.2020.10.038,,,, +1212,TTK,,10.1016/j.cell.2020.10.038,,,, +1212,CDK1,,10.1016/j.cell.2020.10.038,,,, +1212,AURKA,,10.1016/j.cell.2020.10.038,,,, +1212,CDK5,,10.1002/anie.202004087,,,, +1212,CDK2,,10.1002/anie.202004087,,,, +1213,GSK-3beta,,10.1016/j.cell.2020.10.038,,,, +1213,NEK4,,10.1016/j.cell.2020.10.038,,,, +1213,PRKAA2,,10.1016/j.cell.2020.10.038,,,, +1213,CDK5,,10.1016/j.cell.2020.10.038,,,, +1213,CDK16,,10.1016/j.cell.2020.10.038,,,, +1213,CDK17,,10.1016/j.cell.2020.10.038,,,, +1213,FAK,,10.1016/j.cell.2020.10.038,,,, +1213,PRKAA1,,10.1016/j.cell.2020.10.038,,,, +1213,PTK2B,,10.1016/j.cell.2020.10.038,,,, +1213,STK38,,10.1016/j.cell.2020.10.038,,,, +1213,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +1213,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +1213,AAK1,,10.1016/j.cell.2020.10.038,,,, +1213,NEK9,,10.1016/j.cell.2020.10.038,,,, +1213,STK35,,10.1016/j.cell.2020.10.038,,,, +1213,AURKB,,10.1016/j.cell.2020.10.038,,,, +1213,NEK1,,10.1016/j.cell.2020.10.038,,,, +1213,STK33,,10.1016/j.cell.2020.10.038,,,, +1213,CDK12,,10.1016/j.cell.2020.10.038,,,, +1213,TBK1,,10.1016/j.cell.2020.10.038,,,, +1213,IRAK3,,10.1016/j.cell.2020.10.038,,,, +1213,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +1213,CDK9,,10.1016/j.cell.2020.10.038,,,, +1213,CDK7,,10.1016/j.cell.2020.10.038,,,, +1213,NEK3,,10.1016/j.cell.2020.10.038,,,, +1213,GSK3A,,10.1016/j.cell.2020.10.038,,,, +1213,CLK1,,10.1016/j.cell.2020.10.038,,,, +1213,MAPK9,,10.1016/j.cell.2020.10.038,,,, +1213,MAPK8,,10.1016/j.cell.2020.10.038,,,, +1213,TEC,,10.1016/j.cell.2020.10.038,,,, +1213,TTK,,10.1016/j.cell.2020.10.038,,,, +1213,Wee1,,10.1016/j.cell.2020.10.038,,,, +1213,FER,,10.1016/j.cell.2020.10.038,,,, +1213,CDK1,,10.1016/j.cell.2020.10.038,,,, +1213,RPS6KA4,,10.1016/j.cell.2020.10.038,,,, +1213,NUAK1,,10.1016/j.cell.2020.10.038,,,, +1213,AURKA,,10.1016/j.cell.2020.10.038,,,, +1213,CDK2,,10.1002/anie.202004087,,,, +1214,BRD4,,10.1016/j.bioorg.2020.103817,,,, +1215,BRD4,,10.1016/j.bioorg.2020.103817,,,, +1216,BRD4,,10.1016/j.bioorg.2020.103817,,,, +1217,BRD4,,10.1016/j.bioorg.2020.103817,,,, +1218,EGFR,,10.1016/j.bmcl.2020.127167,,,, +1219,EGFR,,10.1016/j.bmcl.2020.127167,,,, +1220,EGFR,,10.1016/j.bmcl.2020.127167,161,68,Degradation of EGFR in PC9 cells after 6 h treatment, +1221,BRD3,,10.1158/0008-5472.CAN-16-2622,,,, +1221,BRD4,,10.1158/0008-5472.CAN-16-2622,,,, +1221,BRD2,,10.1158/0008-5472.CAN-16-2622,,,, +1222,BTK,,10.1182/blood-2018-07-862953,,,, +1222,BTK C481S,,10.1182/blood-2018-07-862953,,,, +1223,BTK C481S,,10.1182/blood-2018-07-862953,,,, +1223,BTK,,10.1182/blood-2018-07-862953,,,, +1224,BTK,,10.1182/blood-2018-07-862953,,,, +1225,SLC9A1,,10.1016/j.chembiol.2020.04.003,,,, +1226,SLC9A4,,10.1016/j.chembiol.2020.04.003,,,, +1226,SLC9A7,,10.1016/j.chembiol.2020.04.003,,,, +1226,SLC9B1,,10.1016/j.chembiol.2020.04.003,,,, +1226,SLC9A1,,10.1016/j.chembiol.2020.04.003,,,, +1226,SLC9A2,,10.1016/j.chembiol.2020.04.003,,,, +1227,SLC9A1,,10.1016/j.chembiol.2020.04.003,,,, +1228,SLC9A1,,10.1016/j.chembiol.2020.04.003,,,, +1229,SLC9A1,,10.1016/j.chembiol.2020.04.003,,,, +1230,MAP4K2,,10.1016/j.cell.2020.10.038,,,, +1230,FLT3,,10.1016/j.chembiol.2017.10.005,,,, +1230,GAK,,10.1016/j.cell.2020.10.038,,,, +1230,LCK,,10.1016/j.cell.2020.10.038,,,, +1230,Src,,10.1016/j.cell.2020.10.038,,,, +1230,FER,,10.1016/j.cell.2020.10.038,,,, +1230,BLK,,10.1016/j.cell.2020.10.038,,,, +1230,IRAK1,,10.1016/j.cell.2020.10.038,,,, +1230,CDK5,,10.1016/j.cell.2020.10.038,,,, +1230,RIPK1,,10.1016/j.cell.2020.10.038,,,, +1230,p38alpha,,10.1016/j.cell.2020.10.038,,,, +1231,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1232,FLT3,,10.1016/j.chembiol.2017.10.005,,,, +1233,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1234,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1235,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1236,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1237,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1238,FLT3,,10.1016/j.chembiol.2017.10.005,,N.D.,, +1239,BTK,,10.1016/j.chembiol.2017.10.005,,,, +1240,BTK,,10.1016/j.chembiol.2017.10.005,,,, +1241,Wee1,,10.1016/j.chembiol.2019.10.013,,,, +1242,Wee1,,10.1016/j.chembiol.2019.10.013,,,, +1243,Wee1,,10.1016/j.chembiol.2019.10.013,,,, +1244,Wee1,,10.1016/j.chembiol.2019.10.013,,,, +1244,TBCK,,10.1016/j.cell.2020.10.038,,,, +1244,COQ8A,,10.1016/j.cell.2020.10.038,,,, +1244,PDK2,,10.1016/j.cell.2020.10.038,,,, +1244,PDK1,,10.1016/j.cell.2020.10.038,,,, +1244,PRKCI,,10.1016/j.cell.2020.10.038,,,, +1244,PAK4,,10.1016/j.cell.2020.10.038,,,, +1244,PDK3,,10.1016/j.cell.2020.10.038,,,, +1244,MKNK2,,10.1016/j.cell.2020.10.038,,,, +1245,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1246,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1247,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1248,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1249,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1250,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1251,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1252,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1253,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1254,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1255,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1256,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1257,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1258,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1259,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1260,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1261,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1262,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1263,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1264,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1265,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1266,PD-L1,21/35 (WB),10.1016/j.ejmech.2020.112377,,,,% PD-L1 degradation in MDA-MB-231 cells after 24 h treatment at 1/10 μM +1267,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1268,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1269,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1270,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1271,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1272,PD-L1,,10.1016/j.ejmech.2020.112377,,,, +1273,BCL-xL,69 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1274,BCL-xL,41 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1275,BCL-xL,40 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1276,BCL-xL,71 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1277,BCL-xL,45 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1278,BCL-xL,20 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1279,BCL-xL,0 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1280,BCL-xL,0 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1281,BCL-xL,84 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1282,BCL-xL,89 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1283,BCL-xL,85 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1284,BCL-xL,90 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1285,BCL-xL,85 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1286,BCL-xL,73 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1287,BCL-xL,27 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1288,BCL-xL,0 (WB),10.1016/j.ejmech.2020.112397,,,,% BCL-xL degradation in MyLa 1929 cells after 16 h treatment at 500 nM +1289,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1290,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1291,PARP1,,10.1038/s41589-019-0379-2,,,, +1292,PARP1,,10.1038/s41589-019-0379-2,,,, +1293,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1294,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1295,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1296,PARP1,,10.1038/s41589-019-0379-2,,,, +1297,PARP1,,10.1038/s41589-019-0379-2,,,, +1298,PARP1,,10.1038/s41589-019-0379-2,,,, +1299,PARP3,,10.1038/s41589-019-0379-2,,,, +1299,PARP1,,10.1038/s41589-019-0379-2,35.7,90,Degradation of PARP1 in Primary Cardiomyocytes after 24 h treatment, +1300,PARP3,,10.1038/s41589-019-0379-2,,,, +1300,PARP1,,10.1038/s41589-019-0379-2,81.8,92,Degradation of PARP1 in Primary Cardiomyocytes after 24 h treatment, +1301,PARP1,,10.1038/s41589-019-0379-2,,,, +1302,PARP1,,10.1038/s41589-019-0379-2,,,, +1303,PARP1,,10.1038/s41589-019-0379-2,,,, +1304,PARP2,,10.1038/s41589-019-0379-2,,,, +1304,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1305,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1305,PARP2,,10.1038/s41589-019-0379-2,,,, +1306,PARP2,,10.1038/s41589-019-0379-2,62.8,,Degradation of PARP2 in HeLa cells after 24 h treatment, +1306,PARP1,,10.1038/s41589-019-0379-2,,,, +1307,PARP2,,10.1038/s41589-019-0379-2,,,, +1307,PARP1,,10.1038/s41589-019-0379-2,,,, +1308,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1309,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1310,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1311,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1312,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1313,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1314,PARP1,,10.1038/s41589-019-0379-2,,N.D.,, +1315,PARP1,,10.1038/s41589-019-0379-2,,,, +1316,TRIM24,20/29/2/39/72 (WB),10.1038/s41589-018-0010-y,,,,% TRIM24 degradation in 293FT cells after 24 h treatment at 0.25/0.5/1/2.5/5 μM +1317,TRIM24,16/38/40 (WB),10.1038/s41589-018-0010-y,,,,% TRIM24 degradation in 293FT cells after 24 h treatment at 0.5/5/10 μM +1318,FKBP12 F36V,,10.1038/s41589-018-0021-8,,,, +1319,FKBP12 F36V,,10.1038/s41589-018-0021-8,,,, +1320,FKBP12 F36V,,10.1038/s41589-018-0021-8,,,, +1321,FKBP12 F36V,,10.1038/s41589-018-0021-8,,,, +1322,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1323,HDAC6,,10.1016/j.chembiol.2020.04.008,1.94,,Degradation of HDAC6 in MM1S after 6 h treatment by in-cell ELISA analysis, +1324,HDAC6,,10.1016/j.chembiol.2020.04.008,,N.D.,, +1325,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1326,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1327,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1328,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1329,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1330,HDAC6,,10.1016/j.chembiol.2020.04.008,,,, +1331,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1331,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1332,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1332,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1333,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1333,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1334,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1334,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1335,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1335,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1336,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1336,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1337,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1337,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1338,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1338,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1339,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1339,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1340,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1340,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1341,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1341,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1342,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1342,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1343,Beta-tubulin,,10.3390/cells9051083,,N.D.,, +1343,Alpha-tubulin,,10.3390/cells9051083,,N.D.,, +1344,Tau,,10.7554/eLife.45457,,75/95,, +1345,Rpn13,,10.1038/s41375-019-0467-z,,95,, +1346,Src,,10.3390/molecules25081948,,,, +1346,IGF-1R,,10.3390/molecules25081948,,,, +1347,IGF-1R,,10.3390/molecules25081948,,,, +1347,Src,,10.3390/molecules25081948,,,, +1348,Src,,10.3390/molecules25081948,,,, +1348,IGF-1R,,10.3390/molecules25081948,,,, +1349,Src,,10.3390/molecules25081948,,,, +1349,IGF-1R,,10.3390/molecules25081948,,,, +1350,IGF-1R,,10.3390/molecules25081948,,,, +1350,Src,,10.3390/molecules25081948,,,, +1351,Src,,10.3390/molecules25081948,,,, +1351,IGF-1R,,10.3390/molecules25081948,,,, +1352,IGF-1R,,10.3390/molecules25081948,,,, +1352,Src,,10.3390/molecules25081948,,,, +1353,Src,,10.3390/molecules25081948,,,, +1353,IGF-1R,,10.3390/molecules25081948,,,, +1354,Src,,10.3390/molecules25081948,,,, +1354,IGF-1R,,10.3390/molecules25081948,,,, +1355,IGF-1R,,10.3390/molecules25081948,,,, +1355,Src,,10.3390/molecules25081948,,,, +1356,IGF-1R,,10.3390/molecules25081948,,,, +1356,Src,,10.3390/molecules25081948,,,, +1357,NS3,,10.1038/s41467-019-11429-w,669,,Degradation of NS3 in Huh7.5 cells after 4 h treatment, +1358,NS3,,10.1038/s41467-019-11429-w,489,,Degradation of NS3 in Huh7.5 cells after 4 h treatment, +1359,NS3,,10.1038/s41467-019-11429-w,50,,Degradation of NS3 in Huh7.5 cells after 4 h treatment, +1360,BCL-xL,,10.1038/s41467-020-15838-0,46,96.2,Degradation of BCL-xL in WI38 cells after 16 h treatment, +1361,BTK,,10.1039/c9cc08238g,,,, +1362,BTK,,10.1039/c9cc08238g,,,, +1363,BTK,,10.1039/c9cc08238g,,,, +1364,BTK,,10.1039/c9cc08238g,,,, +1365,BTK,,10.1039/c9cc08238g,,,, +1366,BTK,,10.1039/c9cc08238g,,,, +1367,BTK,,10.1039/c9cc08238g,,,, +1368,BTK,,10.1039/c9cc08238g,,,, +1369,BTK,,10.1039/c9cc08238g,,,, +1370,BTK,,10.1039/c9cc08238g,,,, +1371,BTK,,10.1039/c9cc08238g,,,, +1372,BTK,,10.1039/c9cc08238g,,,, +1373,BLK,,10.1039/c9cc08238g,220,75,Degradation of BLK in Ramos cells after 18 h treatment, +1373,BTK,,10.1039/c9cc08238g,136,88,Degradation of BTK in K562 cells after 18 h treatment, +1374,BTK,,10.1039/c9cc08238g,,,, +1375,BTK,,10.1039/c9cc08238g,,,, +1376,BTK,,10.1039/c9cc08238g,,,, +1377,CDK8,,10.1021/acsmedchemlett.8b00011,,N.D.,, +1378,CDK8,,10.1021/acsmedchemlett.8b00011,,,, +1379,CDK8,,10.1021/acsmedchemlett.8b00011,,N.D.,, +1380,BTK,,10.1021/jacs.9b13907,2.2,97,Degradation of BTK in Mino cells after 24 h treatment, +1381,BTK,,10.1021/jacs.9b13907,8.6,91,Degradation of BTK in Mino cells after 24 h treatment, +1382,BTK,,10.1021/jacs.9b13907,1.9,88,Degradation of BTK in Mino cells after 24 h treatment, +1383,BTK,,10.1021/jacs.9b13907,10,68,Degradation of BTK in Mino cells after 24 h treatment, +1384,BTK,,10.1021/jacs.9b13907,35,66,Degradation of BTK in Mino cells after 24 h treatment, +1385,BTK,,10.1021/jacs.9b13907,6,85,Degradation of BTK in Mino cells after 24 h treatment, +1386,BTK,32 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1387,BTK,19 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1388,BTK,14 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1389,BTK,17 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1390,BTK,68 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1391,BTK,77 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1392,BTK,29 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1393,BTK,9 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1394,BTK,2 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1395,BTK,25 (WB),10.1021/jacs.9b13907,,,,% BTK degradation in Mino cells after 24 h treatment at 1 μM +1396,BRD4,,10.1021/acschembio.8b01083,,,, +1397,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1398,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1399,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1400,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1401,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1402,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1403,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1404,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1405,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1406,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1407,c-Met,,10.1021/acschembio.7b00969,,N.D.,, +1408,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1409,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1410,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1411,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1412,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1413,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1414,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1415,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1416,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1417,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1418,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1419,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1420,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1421,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1422,c-KIT,,10.1021/acschembio.7b00969,,N.D.,, +1423,CDK6,,10.1182/blood.2019003604,,,, +1423,CDK4,,10.1182/blood.2019003604,,,, +1424,CDK4,,10.1182/blood.2019003604,,,, +1424,CDK6,,10.1182/blood.2019003604,,,, +1425,CDK6,,10.1182/blood.2019003604,,,, +1425,CDK4,,10.1182/blood.2019003604,,,, +1426,CDK4,,10.1182/blood.2019003604,,,, +1426,CDK6,,10.1182/blood.2019003604,,,, +1427,CDK4,,10.1182/blood.2019003604,,,, +1427,CDK6,,10.1182/blood.2019003604,,,, +1428,CDK6,,10.1182/blood.2019003604,,,, +1428,CDK4,,10.1182/blood.2019003604,,,, +1429,AR,,10.1021/acsmedchemlett.9b00115,<=50/<=50,>=71/51-70,Degradation of AR in LNCaP/VCaP cells after 2-4 h treatment, +1430,AR,,10.1021/acsmedchemlett.9b00115,<=501,51-70,Degradation of AR in LNCaP cells after 2-4 h treatment, +1431,AR,,10.1021/acsmedchemlett.9b00115,<=50,>=71,Degradation of AR in LNCaP cells after 2-4 h treatment, +1432,AR,,10.1021/acsmedchemlett.9b00115,<=50,>=71,Degradation of AR in LNCaP cells after 2-4 h treatment, +1433,AR,,10.1021/acsmedchemlett.9b00115,<=50,>=71,Degradation of AR in LNCaP cells after 2-4 h treatment, +1434,AR,,10.1021/acsmedchemlett.9b00115,<=50,>=71,Degradation of AR in LNCaP cells after 2-4 h treatment, +1435,Tau,,10.3389/fncel.2022.801179,,,, +1436,Tau,,10.3389/fncel.2022.801179,,,, +1437,Tau,,10.3389/fncel.2022.801179,,,, +1438,Tau,,10.3389/fncel.2022.801179,,,, +1439,Tau,,10.3389/fncel.2022.801179,,,, +1440,BRD4,,10.1021/acsmedchemlett.9b00042,,,, +1441,BRD4,,10.1021/acsmedchemlett.9b00042,,,, +1442,AR,,10.1021/acsmedchemlett.9b00424,,,, +1443,AR,,10.1021/acsmedchemlett.9b00424,,,, +1444,BRD4,,10.1021/acsmedchemlett.9b00424,,,, +1445,BRD4,,10.1021/acsmedchemlett.9b00424,,,, +1446,TBK1,,10.1021/acsmedchemlett.9b00424,,,, +1447,TBK1,,10.1021/acsmedchemlett.9b00424,,,, +1448,ERRalpha,,10.1021/acsmedchemlett.9b00424,,,, +1449,BRD4,,10.1021/acsmedchemlett.9b00424,,,, +1450,BRD4,,10.1021/acsmedchemlett.9b00424,,,, +1451,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1452,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1453,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1454,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1455,IRAK4,20-50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1456,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1457,IRAK4,>50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1458,IRAK4,20-50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1459,IRAK4,20-50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1460,IRAK4,20-50/>50/>50,10.1021/acsmedchemlett.9b00423,,,,% IRAK4 degradation in OCILY-10 cells after 4 h treatment at 10/100/1000 nM +1461,IRAK4,,10.1021/acsmedchemlett.9b00385,<30,>70,Degradation of IRAK4 in MCF7 cells, +1462,IRAK4,,10.1021/acsmedchemlett.9b00385,<30,>70,Degradation of IRAK4 in MCF7 cells, +1463,IRAK4,,10.1021/acsmedchemlett.9b00385,<30,>70,Degradation of IRAK4 in MCF7 cells, +1464,IRAK4,,10.1021/acsmedchemlett.9b00385,<30,50-70,Degradation of IRAK4 in MCF7 cells, +1465,IRAK4,,10.1021/acsmedchemlett.9b00385,<30,50-70,Degradation of IRAK4 in MCF7 cells, +1466,IRAK4,,10.1021/acsmedchemlett.9b00385,30-100,>70,Degradation of IRAK4 in MCF7 cells, +1467,ER,,10.1021/acsmedchemlett.9b00397,0.3,,Degradation of ERalpha in MCF7 cells, +1468,ER,,10.1021/acsmedchemlett.9b00397,0.4,,Degradation of ERalpha in MCF7 cells, +1469,ER,,10.1021/acsmedchemlett.9b00397,0.3,,Degradation of ERalpha in MCF7 cells, +1470,ER,,10.1021/acsmedchemlett.9b00397,0.4,,Degradation of ERalpha in MCF7 cells, +1471,ER,,10.1021/acsmedchemlett.9b00397,0.8,,Degradation of ERalpha in MCF7 cells, +1472,ER,,10.1021/acsmedchemlett.9b00397,0.6,,Degradation of ERalpha in MCF7 cells, +1473,EGFR,,10.1021/acsmedchemlett.9b00283,,,, +1473,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1474,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1475,EGFR,,10.1021/acsmedchemlett.9b00283,,,, +1476,EGFR L858R/T790M,24/59/62 (WB),10.1002/anie.202003500,,,,% EGFR degradation in L858R/T790M BaF3 cells after 24 h treatment at 0.01/0.1/1 μM +1476,EGFR L858R/T790M/C797S,74 (WB),10.1002/anie.202003500,,,,% EGFR degradation in L858R/T790M/C797S BaF3 cells after 24 h treatment at 0.1 μM +1476,EGFR L858R/T790M/L718Q,71 (WB),10.1002/anie.202003500,,,,% EGFR degradation in L858R/T790M/L718Q BaF3 cells after 24 h treatment at 0.1 μM +1477,ALK,,10.1021/acsmedchemlett.9b00296,,,, +1478,ALK,,10.1021/acsmedchemlett.9b00296,,,, +1479,ALK,,10.1021/acsmedchemlett.9b00296,,,, +1480,KRAS,<25/>=50/>=50,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1481,KRAS,<25/>=50/>=50,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1482,KRAS,<25/25-50/25-50,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1483,KRAS,<25/25-50/25-50,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1484,KRAS,<25/25-50/25-50,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1485,KRAS,<25/<25/<25,10.1021/acsmedchemlett.9b00584,,,,% KRAS degradation in H2023 cells at 300/1000/3000 nM +1486,SHP2,4/0,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1487,SHP2,9/7,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1488,SHP2,13/6,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1489,SHP2,0/3,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1490,SHP2,0/0,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1491,SHP2,20/14,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1492,SHP2,81/80,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1493,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1494,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1495,SHP2,>95/93,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1496,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1497,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1498,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1499,SHP2,80/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1500,SHP2,32/87,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1501,SHP2,53/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1502,SHP2,85/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1503,SHP2,80/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1504,SHP2,62/90,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1505,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,6/2.6,,Degradation of SHP2 in KYSE520/MV4;11 cells after 12 h treatment,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1506,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1507,SHP2,>95/>95,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1508,SHP2,0/82,10.1021/acs.jmedchem.0c00471,,,,% SHP2 degradation in KYSE520 cells after 6 h treatment at 100/1000 nM +1509,FAK,,10.1021/acsmedchemlett.9b00372,0.37/0.04,,Degradation of FAK in LNCaP/Ramos cells after 8 h treatment, +1509,FAK,,10.1021/acsmedchemlett.9b00372,0.31/0.08/0.33,,Degradation of FAK in TM3/PA1/MDA-MB-436 cells after 8 h treatment, +1509,FAK,,10.1007/s13238-020-00732-8,1.3/0.4,,Degradation of Fak in primary Sertoli/germ cells after 8 h treatment, +1510,BCR-ABL,,10.1021/acs.jmedchem.9b02058,391,,Degradation of BCR-ABL in K562 cells, +1511,BCR-ABL,,10.1021/acs.jmedchem.9b02058,114,,Degradation of BCR-ABL in K562 cells, +1512,BCR-ABL,,10.1021/acs.jmedchem.9b02058,62,,Degradation of BCR-ABL in K562 cells, +1513,BCR-ABL,,10.1021/acs.jmedchem.9b02058,>500,,Degradation of BCR-ABL in K562 cells, +1514,BCR-ABL,,10.1021/acs.jmedchem.9b02058,>500,,Degradation of BCR-ABL in K562 cells, +1515,BRD2,,10.1021/acscentsci.9b00713,,,, +1516,BRD3,,10.1126/sciadv.aay5064,,,, +1516,BRD2,,10.1126/sciadv.aay5064,,,, +1516,BRD4,,10.1126/sciadv.aay5064,,,, +1517,BRD3,,10.1126/sciadv.aay5064,,,, +1517,BRD2,,10.1126/sciadv.aay5064,,,, +1517,BRD4,,10.1126/sciadv.aay5064,,,, +1518,BRD3,,10.1126/sciadv.aay5064,,,, +1518,BRD2,,10.1126/sciadv.aay5064,,,, +1518,BRD4,,10.1126/sciadv.aay5064,,,, +1519,BRD3,,10.1126/sciadv.aay5064,,,, +1519,BRD2,,10.1126/sciadv.aay5064,,,, +1519,BRD4,,10.1126/sciadv.aay5064,,,, +1520,BRD3,,10.1126/sciadv.aay5064,,,, +1520,BRD2,,10.1126/sciadv.aay5064,,,, +1520,BRD4,,10.1126/sciadv.aay5064,,,, +1521,BRD3,,10.1126/sciadv.aay5064,,,, +1521,BRD4,,10.1126/sciadv.aay5064,,,, +1521,BRD2,,10.1126/sciadv.aay5064,,,, +1522,BRD2,,10.1126/sciadv.aay5064,,,, +1522,BRD4,,10.1126/sciadv.aay5064,,,, +1522,BRD3,,10.1126/sciadv.aay5064,,,, +1523,BRD3,,10.1126/sciadv.aay5064,,,, +1523,BRD4,,10.1126/sciadv.aay5064,,,, +1523,BRD2,,10.1126/sciadv.aay5064,,,, +1524,BRD4,,10.1126/sciadv.aay5064,,,, +1524,BRD2,,10.1126/sciadv.aay5064,,,, +1524,BRD3,,10.1126/sciadv.aay5064,,,, +1525,BRD4,,10.1126/sciadv.aay5064,,,, +1525,BRD3,,10.1126/sciadv.aay5064,,,, +1525,BRD2,,10.1126/sciadv.aay5064,,,, +1526,BRD3,,10.1126/sciadv.aay5064,,,, +1526,BRD2,,10.1126/sciadv.aay5064,,,, +1526,BRD4,,10.1126/sciadv.aay5064,,,, +1527,BRD4,,10.1126/sciadv.aay5064,,,, +1527,BRD2,,10.1126/sciadv.aay5064,,,, +1527,BRD3,,10.1126/sciadv.aay5064,,,, +1528,BRD3,,10.1126/sciadv.aay5064,,,, +1528,BRD2,,10.1126/sciadv.aay5064,,,, +1528,BRD4,,10.1126/sciadv.aay5064,,,, +1529,FKBP12,,10.1126/sciadv.aay5064,,,, +1530,FKBP12,,10.1126/sciadv.aay5064,,,, +1531,FKBP12,,10.1126/sciadv.aay5064,,,, +1532,FKBP12,,10.1126/sciadv.aay5064,,,, +1533,FKBP12,,10.1126/sciadv.aay5064,,,, +1534,FKBP12,,10.1126/sciadv.aay5064,,,, +1535,BRD2,,10.1002/anie.201914396,>125,,Degradation of BRD2 in HeLa cells after 4/18 h treatment, +1535,BRD3,,10.1002/anie.201914396,>125,,Degradation of BRD3 in HeLa cells after 4/18 h treatment, +1535,BRD4,,10.1002/anie.201914396,25-125,,Degradation of BRD4 in HeLa cells after 4/18 h treatment, +1536,BRD2,,10.1002/anie.201914396,,,, +1536,BRD3,,10.1002/anie.201914396,,,, +1536,BRD4,,10.1002/anie.201914396,,,, +1537,BTK,,10.1021/acs.biochem.8b00391,,N.D.,, +1538,EGFR L858R/T790M,0/2/19 (WB),10.1002/anie.202003500,,,,% EGFR degradation in L858R/T790M BaF3 cells after 24 h treatment at 0.01/0.1/1 μM +1539,BTK,,10.1021/acs.biochem.8b00391,,N.D.,, +1540,EGFR L858R/T790M,17/45/40 (WB),10.1002/anie.202003500,,,,% EGFR degradation in L858R/T790M BaF3 cells after 24 h treatment at 0.01/0.1/1 μM +1541,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1542,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1543,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1544,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1545,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1546,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1547,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1548,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1549,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1550,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1551,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1552,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1553,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1554,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1555,EGFR L858R/T790M,,10.1002/anie.202003500,,,, +1556,AR,,10.1021/acsmedchemlett.0c00194,,,, +1557,AR,,10.1021/acsmedchemlett.0c00194,,,, +1558,AR,,10.1021/acsmedchemlett.0c00194,,,, +1559,AR,,10.1021/acsmedchemlett.0c00194,,,, +1560,AR,,10.1021/acsmedchemlett.0c00194,,N.D.,, +1561,AR,,10.1021/acsmedchemlett.0c00194,10,33,Degradation of AR in LNCaP cells after 6 h treatment, +1562,AR,,10.1021/acsmedchemlett.0c00194,,,, +1563,AR,,10.1021/acsmedchemlett.0c00194,,,, +1564,AR,,10.1021/acsmedchemlett.0c00194,,,, +1565,AR,,10.1021/acsmedchemlett.0c00194,,,, +1566,AR,,10.1021/acsmedchemlett.0c00194,,,, +1567,AR,,10.1021/acsmedchemlett.0c00194,,,, +1568,AR,,10.1021/acsmedchemlett.0c00194,,,, +1569,AR,,10.1021/acsmedchemlett.0c00194,,,, +1570,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1571,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1572,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1573,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1574,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1575,Alpha-syn,,10.1021/acsmedchemlett.0c00192,,,, +1576,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1576,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1576,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1577,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1577,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1577,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1578,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1578,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1578,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1579,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1579,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1579,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1580,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1580,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1580,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1581,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1581,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1581,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1582,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1582,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1582,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1583,TRKA,,10.1021/acsmedchemlett.0c00235,,,, +1583,TRKB,,10.1021/acsmedchemlett.0c00235,,,, +1583,TRKC,,10.1021/acsmedchemlett.0c00235,,,, +1584,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/51-70,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1585,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/51-70,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1586,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/51-70,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1587,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/>=71,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1588,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/>=71,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1589,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/>=71,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1590,AR,,10.1021/acsmedchemlett.0c00236,<=50/<=50,>=71/>=71,"Degradation of AR in LNCaP/VCaP cells using ELISA assay (DC50: 15min, Dmax: 4h)", +1591,BRD4,,10.1038/s41589-019-0304-8,,,, +1592,BRD4,,10.1038/s41589-019-0304-8,,,, +1593,PDEdelta,,10.1021/acs.jmedchem.0c00929,30000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1594,PDEdelta,,10.1021/acs.jmedchem.0c00929,25000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1595,PDEdelta,,10.1021/acs.jmedchem.0c00929,22000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1596,PDEdelta,,10.1021/acs.jmedchem.0c00929,15000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1597,PDEdelta,,10.1021/acs.jmedchem.0c00929,14000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1598,PDEdelta,,10.1021/acs.jmedchem.0c00929,3600,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1599,PDEdelta,,10.1021/acs.jmedchem.0c00929,30000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1600,PDEdelta,,10.1021/acs.jmedchem.0c00929,10000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1601,PDEdelta,,10.1021/acs.jmedchem.0c00929,5000,,Degradation of PDEdelta in SW480 cells after 24 h treatment, +1602,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>10000,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1603,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>10000,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1604,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>10000,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1605,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>10000,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1606,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>10000,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1607,BCR-ABL,,10.1021/acs.jmedchem.0c00967,56,,Degradation of BCR-ABL in K562 cells after 48 h treatment, +1608,BCR-ABL,,10.1021/acs.jmedchem.0c00967,56,,Degradation of BCR-ABL in K562 cells after 48 h treatment, +1609,BCR-ABL,,10.1021/acs.jmedchem.0c00967,20,,Degradation of BCR-ABL in K562 cells after 48 h treatment, +1610,BCR-ABL,,10.1021/acs.jmedchem.0c00967,56,,Degradation of BCR-ABL in K562 cells after 48 h treatment, +1611,BCR-ABL,,10.1021/acs.jmedchem.0c00967,10,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1612,BCR-ABL,,10.1021/acs.jmedchem.0c00967,>625,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1613,BCR-ABL,,10.1021/acs.jmedchem.0c00967,400,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1614,BCR-ABL,,10.1021/acs.jmedchem.0c00967,300,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1615,BCR-ABL T315I,,10.1021/acs.jmedchem.0c00967,,,, +1615,BCR-ABL,,10.1021/acs.jmedchem.0c00967,200,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1616,BCR-ABL,,10.1021/acs.jmedchem.0c00967,500,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1617,BCR-ABL,,10.1021/acs.jmedchem.0c00967,625,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1618,BCR-ABL,,10.1021/acs.jmedchem.0c00967,70,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1619,BCR-ABL,,10.1021/acs.jmedchem.0c00967,70,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1620,BCR-ABL T315I,,10.1021/acs.jmedchem.0c00967,,,, +1620,BCR-ABL V468F,,10.1021/acs.jmedchem.0c00967,,,, +1620,BCR-ABL H396R,,10.1021/acs.jmedchem.0c00967,,,, +1620,BCR-ABL E255K,,10.1021/acs.jmedchem.0c00967,,,, +1620,BCR-ABL,,10.1021/acs.jmedchem.0c00967,20,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1621,BCR-ABL,,10.1021/acs.jmedchem.0c00967,70,,Degradation of BCR-ABL in K562 cells after 32 h treatment, +1622,BCR-ABL T315I,,10.1021/acs.jmedchem.0c00967,,,, +1623,BCR-ABL,,10.1021/acschembio.0c00348,,,, +1624,BCR-ABL,,10.1021/acschembio.0c00348,,,, +1625,p38alpha,8/0 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1626,p38alpha,40/0 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1627,p38alpha,60/0 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1628,p38alpha,55/0 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1629,p38alpha,82/20 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1630,p38alpha,78/26 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1631,p38alpha,92/41 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1632,p38alpha,79/85 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1633,p38alpha,0.5/76 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1634,p38alpha,67/47 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1635,p38alpha,77/82 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1636,p38alpha,,10.1016/j.ejmech.2020.112451,2.9/18.4,,Degradation of p38alpha in T47D/MB-MDA-231 cells after 24 h treatment, +1636,p38beta,,10.1016/j.ejmech.2020.112451,35.19/19.1,,Degradation of p38beta in T47D/MB-MDA-231 cells after 24 h treatment, +1637,p38alpha,74/16 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1638,p38alpha,0/7 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1639,p38alpha,36/42 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1640,p38alpha,60/68 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1641,p38alpha,40/25 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1642,p38alpha,12/40 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1643,p38alpha,84/91 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1644,p38alpha,74/87 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1645,p38alpha,,10.1016/j.ejmech.2020.112451,24/27.2,,Degradation of p38alpha in T47D/MB-MDA-231 cells after 24 h treatment, +1645,p38beta,,10.1016/j.ejmech.2020.112451,48.47/48.9,,Degradation of p38beta in T47D/MB-MDA-231 cells after 24 h treatment, +1646,p38alpha,81/93 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1647,p38alpha,0/4 (WB),10.1016/j.ejmech.2020.112451,,,,% p38alpha degradation in BBL358/T47D cells after 24 h treatment at 10 μM +1648,BCR-ABL,,10.1039/d0cc02201b,30,,Degradation of BCR-ABL in K562 cells after 24 h treatment, +1649,BCL-xL,,10.1021/acschembio.0c00266,4.8,76,Degradation of BCL-xL in THP-1 cells after 24 h treatment, +1650,BTK,,10.1073/pnas.1803662115,9.6,,Degradation of BTK in Ramos cells after 24 h treatment, +1651,BRD4,,10.1021/acschembio.9b00092,,,, +1651,BRD2,,10.1021/acs.jmedchem.6b01912,,37,, +1651,BRD2,,10.1021/acschembio.9b00092,,,, +1651,BRD3,,10.1021/acschembio.9b00092,,,, +1651,BRD3,,10.1021/acs.jmedchem.6b01912,158,74,Degradation of BRD3 in HeLa cells after 24 h treatment, +1651,BRD4,,10.1021/acs.jmedchem.6b01912,126/200,94/78,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +1652,BRD2,,10.1021/acs.jmedchem.6b01912,,43,, +1652,BRD4,,10.1021/acs.jmedchem.6b01912,8/25,98/95,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +1652,BRD3,,10.1021/acs.jmedchem.6b01912,50,91,Degradation of BRD3 in HeLa cells after 24 h treatment, +1653,BRD4,,10.1021/acs.jmedchem.6b01912,8/32,95/93,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +1653,BRD3,,10.1021/acschembio.9b00092,,,, +1653,BRD4,,10.1021/acschembio.9b00092,,,, +1653,BRD3,,10.1021/acs.jmedchem.6b01912,20,92,Degradation of BRD3 in HeLa cells after 24 h treatment, +1653,BRD2,,10.1021/acs.jmedchem.6b01912,,26,, +1653,BRD2,,10.1021/acschembio.9b00092,,,, +1654,BRD4,,10.1021/acs.jmedchem.6b01912,100/100,96/97,Degradation of BRD4 short/long in HeLa cells after 24 h treatment, +1654,BRD3,,10.1021/acs.jmedchem.6b01912,316,97,Degradation of BRD3 in HeLa cells after 24 h treatment, +1654,BRD2,,10.1021/acs.jmedchem.6b01912,631,93,Degradation of BRD2 in HeLa cells after 24 h treatment, +1655,FAK,,10.1021/acs.jmedchem.8b01826,158/50/13,79/93/93,Degradation of Fak in HLE/HuH-7/SNU-423 cells after 18 h treatment, +1655,FAK,,10.1021/acs.jmedchem.8b01826,398/3/13,30/95/90,Degradation of Fak in HLF/SNU-398/HUCCT1 cells after 18 h treatment, +1655,FAK,,10.1021/acs.jmedchem.8b01826,27/13/25,95/96/90,Degradation of Fak in A549/Hep3B2.1-7/SNU-387 cells after 18 h treatment, +1655,FAK,,10.1021/acs.jmedchem.8b01826,251/32/32,50/89/89,Degradation of Fak in HUH-1/HepG2/SK-Hep-1 cells after 18 h treatment, +1656,FAK,,10.1021/acs.jmedchem.8b01826,79/631/126,79/65/87,Degradation of Fak in HUH-1/HepG2/SK-Hep-1 cells after 18 h treatment, +1656,FAK,,10.1021/acs.jmedchem.8b01826,243/631/32,80/59/98,Degradation of Fak in A549/Hep3B2.1-7/SNU-387 cells after 18 h treatment, +1656,FAK,,10.1021/acs.jmedchem.8b01826,25/100/79,85/79/87,Degradation of Fak in HLE/HuH-7/SNU-423 cells after 18 h treatment, +1656,FAK,,10.1021/acs.jmedchem.8b01826,40/10/126,66/99/86,Degradation of Fak in HLF/SNU-398/HUCCT1 cells after 18 h treatment, +1657,KRAS G12C,,10.1021/acscentsci.0c00411,,30,, +1658,KRAS G12C,,10.1021/acscentsci.0c00411,250/520,90/40,Degradation of KRAS G12C in NCI-H23/NCI-H358 cells after 24 h treatment, +1658,KRAS G12C,,10.1021/acscentsci.0c00411,590/320/760,80/75/90,Degradation of KRAS G12C in NCI-H2030/MIA PaCa-2/SW1573 cells after 24 h treatment, +1659,KRAS G12C,,10.1021/acscentsci.0c00411,640,85,Degradation of KRAS G12C in NCI-H2030 cells after 24 h treatment, +1660,KRAS G12C,,10.1021/acscentsci.0c00411,880,90,Degradation of KRAS G12C in SW1573 cells after 24 h treatment, +1661,KRAS G12C,,10.1021/acscentsci.0c00411,>10000,50,Degradation of KRAS G12C in SW1573 cells after 24 h treatment, +1662,KRAS G12C,,10.1021/acscentsci.0c00411,,35,, +1663,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1664,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1665,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1666,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1667,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1668,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1669,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1670,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1671,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1672,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1673,PARP1,3/49/97.9/91.2 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1674,PARP1,9/98.7/100/99.7 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1675,PARP1,,10.1021/acs.jmedchem.0c00821,0.578/1.08/0.228,>99/>99/>99,Degradation of PARP1 in PC-3/LNCaP/MDA-MB-231 cells after 24 h treatment, +1675,PARP1,,10.1021/acs.jmedchem.0c00821,0.384/0.512/0.263,>99/>99/>99,Degradation of PARP1 in HCC1937/22RV1/MDA-MB-468 cells after 24 h treatment, +1675,PARP1,,10.1021/acs.jmedchem.0c00821,1.26/6.72/0.509,>99/>99/>99,Degradation of PARP1 in MDA-MB-436/Capan-1/SW620 cells after 24 h treatment, +1676,PARP1,59/99.3/100/99.5 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1677,PARP1,64/98.9/99.4/98.8 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1678,PARP1,23/70/90.5/45 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1679,PARP1,29/90/87/42 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1680,PARP1,31/91.8/95.6/95.1 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1681,PARP1,32/93.3/94.7/93.2 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1682,PARP1,26/92.2/97.5/93.5 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1683,PARP1,52/96.9/99.7/96 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1684,PARP1,2/53/97.5/99.1 (WB),10.1021/acs.jmedchem.0c00821,,,,% PARP1 degradation in MDA-MB-436 cells after 24 h treatment at 0.001/0.01/0.1/1 μM +1685,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1686,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1687,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1688,PARP1,,10.1021/acs.jmedchem.0c00821,,,, +1689,TRKA,15/45/93,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1690,TRKA,9/15/65,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1691,TRKA,12/63/94,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1692,TRKA,20/69/93,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1693,TRKB,70/70/80/60 (WB),10.1021/acs.jmedchem.0c01342,,,,% AGBL4-TRKB degradation in KM12 cells after 6 h treatment at 19/56/167/500 nM +1693,TRKA,18/65/96,10.1021/acs.jmedchem.0c01342,0.48/1.26,,Degradation of TPM3-TRKA/TRKA in KM12/HEL cells after 6 h treatment,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1693,TRKC,30/40/60/60 (WB),10.1021/acs.jmedchem.0c01342,,,,% ETV6-TRKC degradation in KM12 cells after 6 h treatment at 19/56/167/500 nM +1694,TRKA,21/23/90,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1695,TRKA,20/21/83,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1696,TRKB,50/50/50/30 (WB),10.1021/acs.jmedchem.0c01342,,,,% AGBL4-TRKB degradation in KM12 cells after 6 h treatment at 19/56/167/500 nM +1696,TRKA,46/82/96,10.1021/acs.jmedchem.0c01342,0.36/2.23,,Degradation of TPM3-TRKA/TRKA in KM12/HEL cells after 6 h treatment,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1696,TRKC,20/60/60/60 (WB),10.1021/acs.jmedchem.0c01342,,,,% ETV6-TRKC degradation in KM12 cells after 6 h treatment at 19/56/167/500 nM +1697,TRKA,30/56/95,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1698,TRKA,22/28/86,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1699,TRKA,22/40/91,10.1021/acs.jmedchem.0c01342,,,,% TPM3-TRKA degradation in KM12 cells after 6 h treatment at 0.1/1/10 nM +1700,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1701,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1702,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1703,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1704,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1705,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1706,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1707,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1708,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1709,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1710,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1711,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1712,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1713,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1714,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1715,IRAK3,,10.1021/acs.jmedchem.0c01125,,,, +1716,IRAK3,,10.1021/acs.jmedchem.0c01125,52,74,Degradation of IRAK3 in THP1 cells after 16 h treatment, +1717,IRAK3,,10.1021/acs.jmedchem.0c01125,2,98,Degradation of IRAK3 in THP1 cells after 16 h treatment, +1718,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1718,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1719,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1719,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1720,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1720,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1721,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1721,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1722,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1722,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1723,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1723,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1724,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1724,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1725,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1725,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1726,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1726,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1727,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1727,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1728,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1728,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1729,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1729,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1730,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1730,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1731,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1731,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1732,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1732,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1733,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1733,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1734,MEK1,,10.1021/acs.jmedchem.0c01609,18/16,,Degradation of MEK1 in HT-29/SK-MEL-28 cells after 24 h treatment, +1734,MEK2,,10.1021/acs.jmedchem.0c01609,8/6,,Degradation of MEK2 in HT-29/SK-MEL-28 cells after 24 h treatment, +1735,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1735,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1736,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1736,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1737,MEK2,,10.1021/acs.jmedchem.0c01609,9/4,,Degradation of MEK2 in HT-29/SK-MEL-28 cells after 24 h treatment, +1737,MEK1,,10.1021/acs.jmedchem.0c01609,18/10,,Degradation of MEK1 in HT-29/SK-MEL-28 cells after 24 h treatment, +1738,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1738,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1739,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1739,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1740,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1740,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1741,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1741,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1742,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1742,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1743,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1743,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1744,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1744,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1745,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1745,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1746,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1746,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1747,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1747,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1748,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1748,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1749,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1749,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1750,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1750,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1751,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1751,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1752,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1752,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1753,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1753,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1754,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1754,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1755,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1755,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1756,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1756,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1757,MEK1,,10.1021/acs.jmedchem.0c01609,,,, +1757,MEK2,,10.1021/acs.jmedchem.0c01609,,,, +1758,MEK2,,10.1021/acs.jmedchem.0c01609,55/38,,Degradation of MEK2 in HT-29/SK-MEL-28 cells after 24 h treatment, +1758,MEK1,,10.1021/acs.jmedchem.0c01609,118/94,,Degradation of MEK1 in HT-29/SK-MEL-28 cells after 24 h treatment, +1759,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1760,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1761,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1762,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1763,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1764,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1765,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1766,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1767,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1768,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1769,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1770,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1771,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1772,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1773,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1774,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1775,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1776,EZH2,,10.1021/acs.jmedchem.0c02234,,,, +1777,PRMT5,0/0/0 (WB),10.1021/acs.jmedchem.0c01111,,,,% PRMT5 degradation in MCF-7 cells after 6 d treatment at 0.2/1/5 μM +1778,PRMT5,0/0/0 (WB),10.1021/acs.jmedchem.0c01111,,,,% PRMT5 degradation in MCF-7 cells after 6 d treatment at 0.2/1/5 μM +1779,PRMT5,0/13/19 (WB),10.1021/acs.jmedchem.0c01111,,,,% PRMT5 degradation in MCF-7 cells after 6 d treatment at 0.2/1/5 μM +1780,PRMT5,13/27/14 (WB),10.1021/acs.jmedchem.0c01111,,,,% PRMT5 degradation in MCF-7 cells after 6 d treatment at 0.2/1/5 μM +1781,PRMT5,17/39/67 (WB),10.1021/acs.jmedchem.0c01111,,,,% PRMT5 degradation in MCF-7 cells after 6 d treatment at 0.2/1/5 μM +1782,PRMT5,,10.1021/acs.jmedchem.0c01111,1100,74,Degradation of PRMT5 in MCF-7 cells after 6 d treatment, +1783,BRD4,,10.1021/acs.jmedchem.0c01846,7.5,98,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1784,BRD4,,10.1021/acs.jmedchem.0c01846,0.095,96,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1785,BRD4,,10.1021/acs.jmedchem.0c01846,180,99,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1786,BRD4,,10.1021/acs.jmedchem.0c01846,3.4,98,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1787,BRD4,,10.1021/acs.jmedchem.0c01846,2.1,98,Degradation of BRD4 in EOL-1 cells 4 h treatment, +1788,BRD4,,10.1021/acs.jmedchem.0c01846,1.4,100,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1789,BRD4,,10.1021/acs.jmedchem.0c01845,>20000,,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1790,BRD4,,10.1021/acs.jmedchem.0c01845,930,79,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1791,BRD4,,10.1021/acs.jmedchem.0c01845,780,99,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1792,BRD4,,10.1021/acs.jmedchem.0c01845,350,100,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1793,BRD4,,10.1021/acs.jmedchem.0c01845,85,98,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1794,BRD4,,10.1021/acs.jmedchem.0c01845,280,88,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1795,BRD4,,10.1021/acs.jmedchem.0c01845,87,100,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1796,BRD4,,10.1021/acs.jmedchem.0c01845,6500,100,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1797,BRD4,,10.1021/acs.jmedchem.0c01845,7.2,99,Degradation of BRD4 in PC3-S1 cells after 4 h treatment, +1798,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1799,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1800,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1801,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1802,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1803,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1804,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1805,IRAK4,,10.1021/acsmedchemlett.0c00474,,,, +1806,FAK,37/71,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1807,FAK,32/60,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1808,FAK,5/22,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1809,FAK,55/81,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1810,FAK,40/65,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1811,FAK,10/30,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1812,FAK,32/90,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1813,FAK,71/96,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1814,FAK,35/92,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1815,FAK,40/92,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1816,FAK,46/94,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1817,FAK,30/82,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1818,FAK,67/93,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1819,FAK,62/90,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1820,FAK,62/90,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1821,FAK,62/90,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1822,FAK,85/95,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1823,FAK,62/90,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1824,FAK,40/85,10.1021/acsmedchemlett.9b00372,,,,% FAK degradation in PA1 cells after 8 h treatment at 1/10 nM +1825,SIRT2,61/47/15 (WB),10.1021/acsmedchemlett.0c00423,,,,% SIRT2 degradation in MCF7 cells after 48 h treatment at 5/10/25 μM +1826,SIRT2,71/38/13 (WB),10.1021/acsmedchemlett.0c00423,,,,% SIRT2 degradation in MCF7 cells after 48 h treatment at 5/10/25 μM +1827,HPGDS,,10.1021/acsmedchemlett.0c00605,,,, +1828,HPGDS,,10.1021/acsmedchemlett.0c00605,,N.D.,, +1829,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1830,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1831,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1832,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1833,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1834,IDO1,,10.1016/j.apsb.2020.02.010,2840,93,Degradation of IDO1 in HeLa cells after 24 h treatment, +1835,IDO1,,10.1016/j.apsb.2020.02.010,,N.D.,, +1836,SHP2,,10.1016/j.bioorg.2021.104788,,,, +1837,SHP2,,10.1016/j.bioorg.2021.104788,,,, +1838,SHP2,,10.1016/j.bioorg.2021.104788,,,, +1839,SHP2,,10.1016/j.bioorg.2021.104788,,,, +1840,ADRA1A,,10.1016/j.apsb.2020.01.014,4320,,Degradation of ADRA1A in HEK293 cells after 12 h treatment, +1841,ADRA1A,,10.1016/j.apsb.2020.01.014,,,, +1842,ADRA1A,,10.1016/j.apsb.2020.01.014,2860,94,Degradation of ADRA1A in HEK293 cells after 12 h treatment, +1843,HDAC1,,10.1002/anie.202006725,,,, +1843,HDAC6,,10.1002/anie.202006725,,,, +1843,HDAC2,,10.1002/anie.202006725,,,, +1843,HDAC3,,10.1002/anie.202006725,,,, +1844,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1845,CD147,,10.1016/j.bioorg.2020.104453,13850,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1846,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1847,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1848,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1849,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1850,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1851,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1852,CD147,,10.1016/j.bioorg.2020.104453,6720,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1853,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1854,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1855,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1856,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1857,CD147,,10.1016/j.bioorg.2020.104453,16840,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1858,CD147,,10.1016/j.bioorg.2020.104453,>40000,,Degradation of CD147 in Sk-Mel-28 cells after 6 h treatment, +1859,HDAC3,,10.1016/j.ejmech.2020.112800,,,, +1860,HDAC3,,10.1016/j.ejmech.2020.112800,,,, +1861,HDAC2,,10.1016/j.ejmech.2020.112800,,,, +1862,HDAC3,,10.1016/j.ejmech.2020.112800,,,, +1863,HDAC3,,10.1016/j.ejmech.2020.112800,,,, +1863,HDAC2,,10.1016/j.ejmech.2020.112800,,,, +1864,HDAC3,,10.1016/j.ejmech.2020.112800,,,, +1865,HDAC3,,10.1016/j.ejmech.2020.112800,320,,Degradation of HDAC3 in RAW 264.7 cells after 24 h treatment, +1866,AR,,10.1016/j.ejmech.2021.113307,,,, +1867,AR,,10.1016/j.ejmech.2021.113307,,,, +1868,AR,,10.1016/j.ejmech.2021.113307,,,, +1869,AR,,10.1016/j.ejmech.2021.113307,,,, +1870,AR,,10.1016/j.ejmech.2021.113307,,,, +1871,AR,,10.1016/j.ejmech.2021.113307,,,, +1872,AR,,10.1016/j.ejmech.2021.113307,,,, +1873,AR,,10.1016/j.ejmech.2021.113307,,,, +1874,AR,,10.1016/j.ejmech.2021.113307,,,, +1875,AR,,10.1016/j.ejmech.2021.113307,,,, +1876,AR,,10.1016/j.ejmech.2021.113307,,,, +1877,AR,,10.1016/j.ejmech.2021.113307,,,, +1878,AR,,10.1016/j.ejmech.2021.113307,,,, +1879,AR,,10.1016/j.ejmech.2021.113307,,,, +1880,AR,,10.1016/j.ejmech.2021.113307,,,, +1881,AR,,10.1016/j.ejmech.2021.113307,,,, +1882,AR,,10.1016/j.ejmech.2021.113307,,,, +1883,AR,,10.1016/j.ejmech.2021.113307,,,, +1884,AR,,10.1016/j.ejmech.2021.113307,,,, +1885,AR,,10.1016/j.ejmech.2021.113307,,,, +1886,AR,,10.1016/j.ejmech.2021.113307,,,, +1887,AR,,10.1016/j.ejmech.2021.113307,,,, +1888,AR,,10.1016/j.ejmech.2021.113307,,,, +1889,AR,,10.1016/j.ejmech.2021.113307,,,, +1890,AR,,10.1016/j.ejmech.2021.113307,,,, +1891,AR,,10.1016/j.ejmech.2021.113307,,,, +1892,AR,,10.1016/j.ejmech.2021.113307,,,, +1893,AR,,10.1016/j.ejmech.2021.113307,,,, +1894,AR,,10.1016/j.ejmech.2021.113307,,,, +1895,AR,,10.1016/j.ejmech.2021.113307,,,, +1896,AR,,10.1016/j.ejmech.2021.113307,,,, +1897,AR,,10.1016/j.ejmech.2021.113307,,,, +1898,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1899,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1900,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1901,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1902,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1903,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1904,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1905,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1906,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1907,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1908,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1909,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1910,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1911,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1912,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1913,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1914,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1915,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1916,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1917,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1918,GSK-3beta,,10.1016/j.ejmech.2020.112949,,,, +1919,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1920,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1921,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1922,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1923,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1924,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1925,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1926,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1927,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1928,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1929,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1930,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1931,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1932,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1933,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1934,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1935,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1936,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1937,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1938,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1939,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1940,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1941,EEF2K,,10.1016/j.ejmech.2020.112505,,,, +1942,EEF2K,,10.1016/j.ejmech.2020.112505,,56.7,, +1943,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1944,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1945,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1946,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1947,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1948,VEGFR-2,,10.1016/j.ejmech.2020.112654,,,, +1949,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1949,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1949,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1950,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1950,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1950,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1951,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1951,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1951,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1952,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1952,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1952,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1953,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1953,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1953,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1954,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1954,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1954,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1955,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1955,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1955,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1956,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1956,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1956,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1957,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1957,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1957,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1958,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1958,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1958,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1959,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1959,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1959,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1960,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1960,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1960,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1961,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1961,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1961,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1962,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1962,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1962,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1963,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1963,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1963,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1964,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1964,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1964,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1965,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1965,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1965,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1966,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1966,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1966,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1967,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1967,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1967,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1968,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1968,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1968,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1969,CDK2,,10.1016/j.ejmech.2020.112903,,,, +1969,CDK4,,10.1016/j.ejmech.2020.112903,,,, +1969,CDK6,,10.1016/j.ejmech.2020.112903,,,, +1970,ALK,,10.1016/j.ejmech.2020.113150,,,, +1971,ALK,,10.1016/j.ejmech.2020.113150,,,, +1972,ALK,,10.1016/j.ejmech.2020.113150,,,, +1973,ALK,,10.1016/j.ejmech.2020.113150,,,, +1974,ALK,,10.1016/j.ejmech.2020.113150,,,, +1975,ALK,,10.1016/j.ejmech.2020.113150,,,, +1976,ALK,,10.1016/j.ejmech.2020.113150,,,, +1977,ALK,,10.1016/j.ejmech.2020.113150,,,, +1978,ALK,,10.1016/j.ejmech.2020.113150,,,, +1979,ALK,,10.1016/j.ejmech.2020.113150,,,, +1980,ALK,,10.1016/j.ejmech.2020.113150,,,, +1981,ALK,,10.1016/j.ejmech.2020.113150,,,, +1982,ALK,,10.1016/j.ejmech.2020.113150,,,, +1983,ALK,,10.1016/j.ejmech.2020.113150,,,, +1984,ALK,,10.1016/j.ejmech.2020.113150,,,, +1985,ALK,,10.1016/j.ejmech.2020.113150,,,, +1986,ALK,,10.1016/j.ejmech.2020.113150,,,, +1987,ALK,,10.1016/j.ejmech.2020.113150,,,, +1988,ALK,,10.1016/j.ejmech.2020.113150,,,, +1989,ALK,,10.1016/j.ejmech.2020.113150,,,, +1990,ALK,,10.1016/j.ejmech.2020.113150,,,, +1991,ALK,,10.1016/j.ejmech.2020.113150,,,, +1992,ALK,,10.1016/j.ejmech.2020.113150,,,, +1993,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +1993,EGFR,,10.1016/j.ejmech.2020.112781,,,, +1993,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +1994,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +1994,EGFR,,10.1016/j.ejmech.2020.112781,,,, +1994,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +1995,EGFR e19d,,10.1016/j.ejmech.2020.112781,0.51,80.4,Degradation of EGFR del19 in HCC827 cells after 48 h treatment, +1995,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,126.2,90.3,Degradation of EGFR L858R/T790M in H1975 cells after 48 h treatment, +1995,EGFR,,10.1016/j.ejmech.2020.112781,,N.D.,, +1996,EGFR e19d,,10.1016/j.ejmech.2020.112781,3.54,74.8,Degradation of EGFR del19 in HCC827 cells after 48 h treatment, +1996,EGFR,,10.1016/j.ejmech.2020.112781,,,, +1996,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,151.2,80.3,Degradation of EGFR L858R/T790M in H1975 cells after 48 h treatment, +1997,EGFR,,10.1016/j.ejmech.2020.112781,,,, +1997,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +1997,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +1998,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +1998,EGFR,,10.1016/j.ejmech.2020.112781,,N.D.,, +1998,EGFR e19d,,10.1016/j.ejmech.2020.112781,1.91,82,Degradation of EGFR del19 in HCC827 cells after 48 h treatment, +1999,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +1999,EGFR,,10.1016/j.ejmech.2020.112781,,,, +1999,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +2000,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +2000,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +2000,EGFR,,10.1016/j.ejmech.2020.112781,,,, +2001,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +2001,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +2001,EGFR,,10.1016/j.ejmech.2020.112781,,,, +2002,EGFR,,10.1016/j.ejmech.2020.112781,,,, +2002,EGFR L858R/T790M,,10.1016/j.ejmech.2020.112781,,,, +2002,EGFR e19d,,10.1016/j.ejmech.2020.112781,,,, +2003,CBP,,10.1016/j.chembiol.2020.12.004,,,, +2003,EP300,,10.1016/j.chembiol.2020.12.004,,,, +2004,IRAK4,,10.1016/j.chembiol.2020.08.010,,46,, +2005,IRAK4,,10.1016/j.chembiol.2020.08.010,485,92,Degradation of IRAK4 in HEK293T cells after 24 h treatment, +2006,IRAK4,,10.1016/j.chembiol.2020.08.010,190,93,Degradation of IRAK4 in HEK293T cells after 24 h treatment, +2007,IRAK4,,10.1016/j.chembiol.2020.08.010,293,97,Degradation of IRAK4 in HEK293T cells after 24 h treatment, +2008,IRAK4,,10.1016/j.chembiol.2020.08.010,405,90,Degradation of IRAK4 in HEK293T cells after 24 h treatment, +2009,IRAK4,,10.1016/j.chembiol.2020.08.010,7420,71,Degradation of IRAK4 in HEK293T cells after 24 h treatment, +2010,IRAK4,,10.1016/j.chembiol.2020.08.010,,47,, +2011,IRAK4,,10.1016/j.chembiol.2020.08.010,,30,, +2012,HDAC3,,10.1039/d0cc03243c,,,, +2013,HDAC3,,10.1039/d0cc03243c,,,, +2014,HDAC3,,10.1039/d0cc03243c,,,, +2015,HDAC3,74/72 (WB),10.1039/d0cc03243c,,,,% HDAC3 degradation in MDA-MB-468 cells after 14 h treatment at 0.1/1 μM +2016,HDAC3,72/84 (WB),10.1039/d0cc03243c,,,,% HDAC3 degradation in MDA-MB-468 cells after 14 h treatment at 0.1/1 μM +2017,HDAC3,,10.1039/d0cc03243c,42,,Degradation of HDAC3 in MDA-MB-468 cells after 14 h treatment, +2018,HDAC3,41/56 (WB),10.1039/d0cc03243c,,,,% HDAC3 degradation in MDA-MB-468 cells after 14 h treatment at 0.1/1 μM +2019,CDK6,,10.1039/d0sc00167h,,,, +2019,CDK4,,10.1039/d0sc00167h,,,, +2020,CDK6,,10.1039/d0sc00167h,,,, +2020,CDK4,,10.1039/d0sc00167h,,,, +2021,CDK4,,10.1039/d0sc00167h,,,, +2021,CDK6,,10.1039/d0sc00167h,,,, +2022,CDK4,,10.1039/d0sc00167h,,,, +2022,CDK6,,10.1039/d0sc00167h,,,, +2023,CDK6,,10.1039/d0sc00167h,,,, +2023,CDK4,,10.1039/d0sc00167h,,,, +2024,CDK6,,10.1039/d0sc00167h,,,, +2024,CDK4,,10.1039/d0sc00167h,,,, +2025,CDK6,,10.1039/d0sc00167h,,,, +2025,CDK4,,10.1039/d0sc00167h,,,, +2026,CDK6,,10.1039/d0sc00167h,,,, +2026,CDK4,,10.1039/d0sc00167h,,,, +2027,CDK4,,10.1039/d0sc00167h,,,, +2027,CDK6,,10.1039/d0sc00167h,,,, +2028,CDK6,,10.1039/d0sc00167h,,,, +2028,CDK4,,10.1039/d0sc00167h,,,, +2029,CDK6,97.1/95.9,10.1039/d0sc00167h,,,,% CDK6 degradation in MM.1S cells after 16 h treatment at 100/1000 nM +2029,CDK4,,10.1039/d0sc00167h,,,, +2030,CDK6,,10.1039/d0sc00167h,,,, +2030,CDK4,,10.1039/d0sc00167h,,,, +2031,CDK6,,10.1039/d0sc00167h,,,, +2031,CDK4,,10.1039/d0sc00167h,,,, +2032,CDK6,,10.1039/d0sc00167h,,,, +2032,CDK4,,10.1039/d0sc00167h,,,, +2033,CDK6,,10.1039/d0sc00167h,,,, +2033,CDK4,,10.1039/d0sc00167h,,,, +2034,CDK6,,10.1039/d0sc00167h,,,, +2034,CDK4,,10.1039/d0sc00167h,,,, +2035,CDK6,,10.1039/d0sc00167h,,,, +2035,CDK4,,10.1039/d0sc00167h,,,, +2036,CDK6,,10.1039/d0sc00167h,,,, +2036,CDK4,,10.1039/d0sc00167h,,,, +2037,CDK4,,10.1039/d0sc00167h,,,, +2037,CDK6,,10.1039/d0sc00167h,,,, +2038,CDK4,,10.1039/d0sc00167h,20,,Degradation of CDK4 in MM.1S cells after 16 h treatment, +2038,CDK6,,10.1039/d0sc00167h,5.1,>95,Degradation of CDK6 in MM.1S cells after 16 h treatment, +2039,CDK6,25/82,10.1039/d0sc00167h,,,,% CDK6 degradation in MM.1S cells after 16 h treatment at 100/1000 nM +2039,CDK4,,10.1039/d0sc00167h,,,, +2040,CDK6,0/0,10.1039/d0sc00167h,,,,% CDK6 degradation in MM.1S cells after 16 h treatment at 100/1000 nM +2040,CDK4,0/0,10.1039/d0sc00167h,,,,% CDK4 degradation in MM.1S cells after 16 h treatment at 100/1000 nM +2041,AURKB,,10.1016/j.cell.2020.10.038,,,, +2041,AURKA,62 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 0.1 μM +2041,AURKA,,10.1016/j.cell.2020.10.038,,,, +2042,AURKA,36 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 1 μM +2043,AURKA,30 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 0.1 μM +2044,AURKA,,10.1038/s41589-020-00652-y,28,,Degradation of AURKA in MV4-11 cells after 6 h treatment, +2045,AURKA,40 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 1 μM +2046,AURKA,2 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 0.1 μM +2047,AURKA,0 (WB),10.1038/s41589-020-00652-y,,,,% AURORA-A degradation in AURORA-A in MV4-11 cells after 6 h treatment at 0.1 μM +2048,BRAF V600E,,10.1038/s41589-020-0609-7,90,84,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2049,BRAF V600E,,10.1038/s41589-020-0609-7,45,65,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2050,BRAF V600E,,10.1038/s41589-020-0609-7,100,51,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2051,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2052,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2053,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2054,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2055,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2056,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2057,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2058,BRAF V600E,,10.1038/s41589-020-0609-7,,,, +2059,BRAF V600E,,10.1038/s41589-020-0609-7,500,50,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2060,BRAF V600E,,10.1038/s41589-020-0609-7,,N.D.,, +2061,BRAF V600E,,10.1038/s41589-020-0609-7,,N.D.,, +2062,BRAF V600E,,10.1038/s41589-020-0609-7,,N.D.,, +2063,BRAF V600E,,10.1038/s41589-020-0609-7,25,71,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2064,BRAF V600E,,10.1038/s41589-020-0609-7,80,72,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2065,BRAF V600E,,10.1038/s41589-020-0609-7,50,74,Degradation of BRAF V600E in A375 cells after 24 h treatment, +2066,BTK,,10.1038/s41589-020-00686-2,,,, +2067,BTK,,10.1038/s41589-020-00686-2,800,,Degradation of BTK in THP-1 cells, +2068,BTK,,10.1038/s41589-020-00686-2,4700,,Degradation of BTK in THP-1 cells, +2069,CDK2,,10.1038/s41589-021-00742-5,,,, +2070,CDK2,,10.1038/s41589-021-00742-5,,,, +2071,CDK2,,10.1038/s41589-021-00742-5,56/13/18,,Degradation of CDK2 in OCI-AML2/OCI-AML3/Ramos cells after 48 h treatment, +2071,CDK2,,10.1038/s41589-021-00742-5,61/12/1,,Degradation of CDK2 in Kasumi-1/NB4/MV-4-11 cells after 48 h treatment, +2071,CDK2,,10.1038/s41589-021-00742-5,43/33/29,,Degradation of CDK2 in Z138/HBL-1/Mino cells after 48 h treatment, +2071,CDK2,,10.1038/s41589-021-00742-5,38/53/11,,Degradation of CDK2 in Jurkat/MOLT-4/U937 cells after 48 h treatment, +2071,CDK2,,10.1038/s41589-021-00742-5,160/4/9,,Degradation of CDK2 in Pfeiffer/DOHH2/K562 cells after 48 h treatment, +2071,CDK2,,10.1038/s41589-021-00742-5,22/8,,Degradation of CDK2 in MM.1S/MDA-MB-231 cells after 48 h treatment, +2072,CDK2,,10.1038/s41589-021-00742-5,,,, +2073,BRAF G466V,,10.1038/s41467-021-21159-7,29/23,80/90,Degradation of BRAF G466V in H1666/CAL-12T cells, +2073,BRAF V600K,,10.1038/s41467-021-21159-7,,,, +2073,BRAF K601E,,10.1038/s41467-021-21159-7,,,, +2073,BRAF G466E,,10.1038/s41467-021-21159-7,,,, +2073,BRAF D594N,,10.1038/s41467-021-21159-7,,,, +2073,BRAF,,10.1038/s41467-021-21159-7,,,, +2073,BRAF G469A,,10.1038/s41467-021-21159-7,15,95,Degradation of BRAF G469A in SK-MEL-246 cells, +2073,BRAF V600E,,10.1038/s41467-021-21159-7,6.8,95,Degradation of BRAF V600E in SK-MEL-28 cells, +2074,BRAF V600K,,10.1038/s41467-021-21159-7,,,, +2074,BRAF K601E,,10.1038/s41467-021-21159-7,,,, +2074,BRAF G469A,,10.1038/s41467-021-21159-7,,,, +2074,BRAF G466E,,10.1038/s41467-021-21159-7,,,, +2074,BRAF V600E,,10.1038/s41467-021-21159-7,,,, +2074,BRAF D594N,,10.1038/s41467-021-21159-7,,,, +2074,BRAF G466V,,10.1038/s41467-021-21159-7,,,, +2074,BRAF,,10.1038/s41467-021-21159-7,,,, +2075,BRAF G466E,,10.1038/s41467-021-21159-7,,,, +2075,BRAF V600E,,10.1038/s41467-021-21159-7,,,, +2075,BRAF V600K,,10.1038/s41467-021-21159-7,,,, +2075,BRAF K601E,,10.1038/s41467-021-21159-7,,,, +2075,BRAF G469A,,10.1038/s41467-021-21159-7,,,, +2075,BRAF D594N,,10.1038/s41467-021-21159-7,,,, +2075,BRAF G466V,,10.1038/s41467-021-21159-7,,,, +2075,BRAF,,10.1038/s41467-021-21159-7,,,, +2076,BTK,,10.1038/s41467-020-17997-6,6.6,,Degradation of BTK in MOLM-14 cells after 24 h treatment, +2077,BTK,,10.1038/s41467-020-17997-6,,,, +2078,BTK,,10.1038/s41467-020-17997-6,,,, +2079,BTK,,10.1038/s41467-020-17997-6,,,, +2080,BTK,,10.1038/s41467-020-17997-6,,,, +2081,BTK,,10.1038/s41467-020-17997-6,,,, +2082,BTK,,10.1038/s41467-020-17997-6,,,, +2083,BTK,,10.1038/s41467-020-17997-6,,,, +2084,BTK,,10.1038/s41467-020-17997-6,,,, +2085,BTK,,10.1038/s41467-020-17997-6,,,, +2086,BTK,,10.1038/s41467-020-17997-6,,,, +2087,BTK,,10.1038/s41467-020-17997-6,,,, +2088,BTK,,10.1038/s41467-020-17997-6,,,, +2089,BTK,,10.1038/s41467-020-17997-6,,,, +2090,BTK,,10.1038/s41467-020-17997-6,,,, +2091,BTK,,10.1038/s41467-020-17997-6,,,, +2092,BTK,,10.1038/s41467-020-17997-6,,,, +2093,BTK,,10.1038/s41467-020-17997-6,,,, +2094,FLT3,,10.1038/s41467-020-17997-6,,,, +2095,FLT3,,10.1038/s41467-020-17997-6,,,, +2096,FLT3,,10.1038/s41467-020-17997-6,,,, +2097,FKBP12 F36V,,10.1038/s41467-020-18377-w,,,, +2098,FKBP12 F36V,,10.1038/s41467-020-18377-w,,,, +2099,PARP1,,10.1080/14756366.2020.1804382,,,, +2100,PARP1,,10.1080/14756366.2020.1804382,5400,,Degradation of PARP1 in SW620 cells after 24 h treatment, +2101,PARP1,,10.1080/14756366.2020.1804382,6200,,Degradation of PARP1 in SW620 cells after 24 h treatment, +2102,AR,,10.1158/1535-7163.MCT-20-0417,2000,,Degradation of AR in 22Rv1 cells after 24 h treatment, +2102,AR-V7,,10.1158/1535-7163.MCT-20-0417,370,,Degradation of AR-V7 in 22Rv1 cells after 24 h treatment, +2103,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2104,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2105,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2106,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2107,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2108,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2109,LRRK2,,10.1002/cmdc.202000872,,N.D.,, +2110,HDAC1,,10.3390/molecules25214991,,,, +2110,HDAC8,,10.3390/molecules25214991,,,, +2110,HDAC6,,10.3390/molecules25214991,,,, +2111,HDAC1,,10.3390/molecules25214991,,,, +2111,HDAC8,,10.3390/molecules25214991,,,, +2111,HDAC6,,10.3390/molecules25214991,,,, +2112,HDAC8,,10.3390/molecules25214991,,,, +2112,HDAC6,,10.3390/molecules25214991,,,, +2112,HDAC1,,10.3390/molecules25214991,,,, +2113,FAK,>85/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2114,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2114,FAK,70-84/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2114,AURKA,,10.1016/j.cell.2020.10.038,,,, +2114,Wee1,,10.1016/j.cell.2020.10.038,,,, +2114,CDK7,,10.1016/j.cell.2020.10.038,,,, +2114,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +2114,MAPK7,,10.1016/j.cell.2020.10.038,,,, +2114,CDK10,,10.1016/j.cell.2020.10.038,,,, +2114,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2114,STK33,,10.1016/j.cell.2020.10.038,,,, +2115,FAK,>85/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2116,FAK,>85/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2116,STK33,,10.1016/j.cell.2020.10.038,,,, +2116,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2116,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2116,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +2116,Wee1,,10.1016/j.cell.2020.10.038,,,, +2116,NUAK1,,10.1016/j.cell.2020.10.038,,,, +2116,AURKA,,10.1016/j.cell.2020.10.038,,,, +2117,FAK,25-49/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2118,FAK,>85/>85,10.1021/acsmedchemlett.0c00290,,,,% FAK degradation in PA-TU-8988T cells after 4 h treatment at 10/100 nM +2119,ER,,10.1021/acsmedchemlett.0c00589,0.5,,Degradation of ERalpha in MCF-7 cells, +2120,ER,,10.1021/acsmedchemlett.0c00589,0.5,,Degradation of ERalpha in MCF-7 cells, +2121,ER,,10.1021/acsmedchemlett.0c00589,0.6,,Degradation of ERalpha in MCF-7 cells, +2122,ER,,10.1021/acsmedchemlett.0c00589,0.6,,Degradation of ERalpha in MCF-7 cells, +2123,ER,,10.1021/acsmedchemlett.0c00589,0.8,,Degradation of ERalpha in MCF-7 cells, +2124,ER,,10.1021/acsmedchemlett.0c00589,0.4,,Degradation of ERalpha in MCF-7 cells, +2125,ER,,10.1021/acsmedchemlett.0c00589,0.4,,Degradation of ERalpha in MCF-7 cells, +2126,ER,,10.1021/acsmedchemlett.0c00589,0.4,,Degradation of ERalpha in MCF-7 cells, +2127,ER,,10.1021/acsmedchemlett.0c00589,0.5,,Degradation of ERalpha in MCF-7 cells, +2128,ER,,10.1021/acsmedchemlett.0c00589,0.4,,Degradation of ERalpha in MCF-7 cells, +2129,ER,,10.1021/acsmedchemlett.0c00589,0.7,,Degradation of ERalpha in MCF-7 cells, +2130,ER,,10.1021/acsmedchemlett.0c00589,0.4,,Degradation of ERalpha in MCF-7 cells, +2131,SMARCA4,,10.1021/acsmedchemlett.0c00347,26,99,Degradation of SMARCA4 in A549 cells, +2131,SMARCA2,,10.1021/acsmedchemlett.0c00347,41,99,Degradation of SMARCA2 in A549 cells, +2132,SMARCA2,,10.1021/acsmedchemlett.0c00347,26,99,Degradation of SMARCA2 in A549 cells, +2132,SMARCA4,,10.1021/acsmedchemlett.0c00347,16,100,Degradation of SMARCA4 in A549 cells, +2133,SMARCA4,,10.1021/acsmedchemlett.0c00347,25,92,Degradation of SMARCA4 in A549 cells, +2133,SMARCA2,,10.1021/acsmedchemlett.0c00347,58,90,Degradation of SMARCA2 in A549 cells, +2134,SMARCA2,,10.1021/acsmedchemlett.0c00347,55,95,Degradation of SMARCA2 in A549 cells, +2134,SMARCA4,,10.1021/acsmedchemlett.0c00347,33,95,Degradation of SMARCA4 in A549 cells, +2135,GSK3A,,10.1016/j.cell.2020.10.038,,N.D.,, +2135,GSK-3beta,,10.1016/j.cell.2020.10.038,,N.D.,, +2136,GSK3A,,10.1016/j.cell.2020.10.038,,N.D.,, +2136,GSK-3beta,,10.1016/j.cell.2020.10.038,,N.D.,, +2137,AURKB,,10.1016/j.cell.2020.10.038,,,, +2137,BMP2K,,10.1016/j.cell.2020.10.038,,,, +2137,NEK9,,10.1016/j.cell.2020.10.038,,,, +2137,AAK1,,10.1016/j.cell.2020.10.038,,,, +2137,MAP4K2,,10.1016/j.cell.2020.10.038,,,, +2137,ITK,,10.1016/j.cell.2020.10.038,,,, +2137,CDK9,,10.1016/j.cell.2020.10.038,,,, +2137,GSK-3beta,,10.1016/j.cell.2020.10.038,,,, +2137,EPHB2,,10.1016/j.cell.2020.10.038,,,, +2137,PAK4,,10.1016/j.cell.2020.10.038,,,, +2137,LATS1,,10.1016/j.cell.2020.10.038,,,, +2137,STK17B,,10.1016/j.cell.2020.10.038,,,, +2137,AURKA,,10.1016/j.cell.2020.10.038,,,, +2137,PLK4,,10.1016/j.cell.2020.10.038,,,, +2138,PAK1,,10.1016/j.cell.2020.10.038,,N.D.,, +2139,CDK19,,10.1016/j.cell.2020.10.038,,N.D.,, +2139,CDK8,,10.1016/j.cell.2020.10.038,,N.D.,, +2140,ULK1,,10.1016/j.cell.2020.10.038,,,, +2140,GAK,,10.1016/j.cell.2020.10.038,,,, +2140,AURKA,,10.1016/j.cell.2020.10.038,,,, +2140,Wee1,,10.1016/j.cell.2020.10.038,,,, +2140,MARK3,,10.1016/j.cell.2020.10.038,,,, +2140,STK17B,,10.1016/j.cell.2020.10.038,,,, +2140,STK17A,,10.1016/j.cell.2020.10.038,,,, +2140,BMP2K,,10.1016/j.cell.2020.10.038,,,, +2140,SNRK,,10.1016/j.cell.2020.10.038,,,, +2140,SIK2,,10.1016/j.cell.2020.10.038,,,, +2140,MARK4,,10.1016/j.cell.2020.10.038,,,, +2140,AURKB,,10.1016/j.cell.2020.10.038,,,, +2140,MARK2,,10.1016/j.cell.2020.10.038,,,, +2140,AAK1,,10.1016/j.cell.2020.10.038,,,, +2140,CDK10,,10.1016/j.cell.2020.10.038,,,, +2140,CDK9,,10.1016/j.cell.2020.10.038,,,, +2141,SNRK,,10.1016/j.cell.2020.10.038,,,, +2141,Wee1,,10.1016/j.cell.2020.10.038,,,, +2141,MARK3,,10.1016/j.cell.2020.10.038,,,, +2141,RPS6KB1,,10.1016/j.cell.2020.10.038,,,, +2141,MARK2,,10.1016/j.cell.2020.10.038,,,, +2141,STK17B,,10.1016/j.cell.2020.10.038,,,, +2141,ULK1,,10.1016/j.cell.2020.10.038,,,, +2141,GAK,,10.1016/j.cell.2020.10.038,,,, +2141,MARK4,,10.1016/j.cell.2020.10.038,,,, +2141,AAK1,,10.1016/j.cell.2020.10.038,,,, +2141,SIK3,,10.1016/j.cell.2020.10.038,,,, +2141,STK17A,,10.1016/j.cell.2020.10.038,,,, +2141,SIK2,,10.1016/j.cell.2020.10.038,,,, +2142,ABL1,,10.1016/j.cell.2020.10.038,,N.D.,, +2143,CSK,,10.1016/j.cell.2020.10.038,,,, +2143,Wee1,,10.1016/j.cell.2020.10.038,,,, +2143,ABL2,,10.1016/j.cell.2020.10.038,,,, +2143,BLK,,10.1016/j.cell.2020.10.038,,,, +2144,ULK3,,10.1016/j.cell.2020.10.038,,,, +2144,BMP2K,,10.1016/j.cell.2020.10.038,,,, +2144,SIK2,,10.1016/j.cell.2020.10.038,,,, +2144,NEK9,,10.1016/j.cell.2020.10.038,,,, +2144,AAK1,,10.1016/j.cell.2020.10.038,,,, +2144,CDK4,,10.1016/j.cell.2020.10.038,,,, +2144,LCK,,10.1016/j.cell.2020.10.038,,,, +2144,STK17B,,10.1016/j.cell.2020.10.038,,,, +2144,ULK1,,10.1016/j.cell.2020.10.038,,,, +2144,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2144,GAK,,10.1016/j.cell.2020.10.038,,,, +2144,CDK6,,10.1016/j.cell.2020.10.038,,,, +2144,LIMK2,,10.1016/j.cell.2020.10.038,,,, +2144,MAPK9,,10.1016/j.cell.2020.10.038,,,, +2144,CDK16,,10.1016/j.cell.2020.10.038,,,, +2144,MAPK8,,10.1016/j.cell.2020.10.038,,,, +2144,Wee1,,10.1016/j.cell.2020.10.038,,,, +2144,EIF2AK2,,10.1016/j.cell.2020.10.038,,,, +2144,FER,,10.1016/j.cell.2020.10.038,,,, +2144,AURKA,,10.1016/j.cell.2020.10.038,,,, +2144,PLK4,,10.1016/j.cell.2020.10.038,,,, +2144,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +2144,CAMKK1,,10.1016/j.cell.2020.10.038,,,, +2144,STK17A,,10.1016/j.cell.2020.10.038,,,, +2145,ULK1,,10.1016/j.cell.2020.10.038,,,, +2145,LATS1,,10.1016/j.cell.2020.10.038,,,, +2145,LCK,,10.1016/j.cell.2020.10.038,,,, +2145,FYN,,10.1016/j.cell.2020.10.038,,,, +2145,YES1,,10.1016/j.cell.2020.10.038,,,, +2145,LYN,,10.1016/j.cell.2020.10.038,,,, +2145,CDK4,,10.1016/j.cell.2020.10.038,,,, +2145,Src,,10.1016/j.cell.2020.10.038,,,, +2145,FER,,10.1016/j.cell.2020.10.038,,,, +2145,CDK11B,,10.1016/j.cell.2020.10.038,,,, +2145,EPHA3,,10.1016/j.cell.2020.10.038,,,, +2145,Wee1,,10.1016/j.cell.2020.10.038,,,, +2145,TTK,,10.1016/j.cell.2020.10.038,,,, +2145,CSK,,10.1016/j.cell.2020.10.038,,,, +2145,TEC,,10.1016/j.cell.2020.10.038,,,, +2145,ABL2,,10.1016/j.cell.2020.10.038,,,, +2145,MAPK8,,10.1016/j.cell.2020.10.038,,,, +2145,MAPK9,,10.1016/j.cell.2020.10.038,,,, +2145,MAPKAPK2,,10.1016/j.cell.2020.10.038,,,, +2145,BLK,,10.1016/j.cell.2020.10.038,,,, +2145,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +2145,PLK1,,10.1016/j.cell.2020.10.038,,,, +2145,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2145,LIMK2,,10.1016/j.cell.2020.10.038,,,, +2145,MAPK12,,10.1016/j.cell.2020.10.038,,,, +2145,EPHB3,,10.1016/j.cell.2020.10.038,,,, +2145,FAK,,10.1016/j.cell.2020.10.038,,,, +2145,TNK2,,10.1016/j.cell.2020.10.038,,,, +2145,MAP4K2,,10.1016/j.cell.2020.10.038,,,, +2145,MAP3K1,,10.1016/j.cell.2020.10.038,,,, +2145,RIPK1,,10.1016/j.cell.2020.10.038,,,, +2145,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2145,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2145,p38beta,,10.1016/j.cell.2020.10.038,,,, +2145,p38alpha,,10.1016/j.cell.2020.10.038,,,, +2145,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +2145,DDR2,,10.1016/j.cell.2020.10.038,,,, +2145,LRRK2,,10.1016/j.cell.2020.10.038,,,, +2145,UHMK1,,10.1016/j.cell.2020.10.038,,,, +2145,MAP4K1,,10.1016/j.cell.2020.10.038,,,, +2145,SIK2,,10.1016/j.cell.2020.10.038,,,, +2145,MKNK2,,10.1016/j.cell.2020.10.038,,,, +2145,MAP3K20,,10.1016/j.cell.2020.10.038,,,, +2145,NLK,,10.1016/j.cell.2020.10.038,,,, +2145,TAOK2,,10.1016/j.cell.2020.10.038,,,, +2145,CDK11A,,10.1016/j.cell.2020.10.038,,,, +2145,MAP4K5,,10.1016/j.cell.2020.10.038,,,, +2145,AURKA,,10.1016/j.cell.2020.10.038,,,, +2145,GAK,,10.1016/j.cell.2020.10.038,,,, +2145,EPHB6,,10.1016/j.cell.2020.10.038,,,, +2145,RIPK2,,10.1016/j.cell.2020.10.038,,,, +2145,BUB1,,10.1016/j.cell.2020.10.038,,,, +2146,SIK2,,10.1016/j.cell.2020.10.038,,,, +2146,MKNK2,,10.1016/j.cell.2020.10.038,,,, +2146,LCK,,10.1016/j.cell.2020.10.038,,,, +2146,YES1,,10.1016/j.cell.2020.10.038,,,, +2146,CDK4,,10.1016/j.cell.2020.10.038,,,, +2146,Src,,10.1016/j.cell.2020.10.038,,,, +2146,FER,,10.1016/j.cell.2020.10.038,,,, +2146,CSK,,10.1016/j.cell.2020.10.038,,,, +2146,MAPK8,,10.1016/j.cell.2020.10.038,,,, +2146,MAPK9,,10.1016/j.cell.2020.10.038,,,, +2146,CLK1,,10.1016/j.cell.2020.10.038,,,, +2146,BLK,,10.1016/j.cell.2020.10.038,,,, +2146,PLK1,,10.1016/j.cell.2020.10.038,,,, +2146,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2146,TNK2,,10.1016/j.cell.2020.10.038,,,, +2146,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2146,UHMK1,,10.1016/j.cell.2020.10.038,,,, +2147,MAPK9,,10.1016/j.cell.2020.10.038,,,, +2147,MAPKAPK2,,10.1016/j.cell.2020.10.038,,,, +2147,BLK,,10.1016/j.cell.2020.10.038,,,, +2147,RPS6KA3,,10.1016/j.cell.2020.10.038,,,, +2147,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2147,TNK2,,10.1016/j.cell.2020.10.038,,,, +2147,MAP3K1,,10.1016/j.cell.2020.10.038,,,, +2147,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2147,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2147,p38alpha,,10.1016/j.cell.2020.10.038,,,, +2147,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +2147,PDIK1L,,10.1016/j.cell.2020.10.038,,,, +2147,UHMK1,,10.1016/j.cell.2020.10.038,,,, +2147,MAP4K1,,10.1016/j.cell.2020.10.038,,,, +2147,SIK2,,10.1016/j.cell.2020.10.038,,,, +2147,MAP3K20,,10.1016/j.cell.2020.10.038,,,, +2147,MKNK2,,10.1016/j.cell.2020.10.038,,,, +2147,GAK,,10.1016/j.cell.2020.10.038,,,, +2147,EPHB6,,10.1016/j.cell.2020.10.038,,,, +2147,BUB1,,10.1016/j.cell.2020.10.038,,,, +2147,ULK1,,10.1016/j.cell.2020.10.038,,,, +2147,PAK4,,10.1016/j.cell.2020.10.038,,,, +2147,ABL1,,10.1016/j.cell.2020.10.038,,,, +2147,LCK,,10.1016/j.cell.2020.10.038,,,, +2147,FYN,,10.1016/j.cell.2020.10.038,,,, +2147,YES1,,10.1016/j.cell.2020.10.038,,,, +2147,CDK4,,10.1016/j.cell.2020.10.038,,,, 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+2192,BLK,,10.1016/j.cell.2020.10.038,,,, +2192,CDK9,,10.1016/j.cell.2020.10.038,,,, +2192,CDK7,,10.1016/j.cell.2020.10.038,,,, +2192,CSNK1E,,10.1016/j.cell.2020.10.038,,,, +2192,CSNK1D,,10.1016/j.cell.2020.10.038,,,, +2192,ABL2,,10.1016/j.cell.2020.10.038,,,, +2192,TEC,,10.1016/j.cell.2020.10.038,,,, +2192,BMPR1A,,10.1016/j.cell.2020.10.038,,,, +2192,Wee1,,10.1016/j.cell.2020.10.038,,,, +2192,CDK2,,10.1016/j.cell.2020.10.038,,,, +2192,FLT1,,10.1016/j.cell.2020.10.038,,,, +2192,FER,,10.1016/j.cell.2020.10.038,,,, +2192,Src,,10.1016/j.cell.2020.10.038,,,, +2192,CDK4,,10.1016/j.cell.2020.10.038,,,, +2192,YES1,,10.1016/j.cell.2020.10.038,,,, +2192,LCK,,10.1016/j.cell.2020.10.038,,,, +2192,STK10,,10.1016/j.cell.2020.10.038,,,, +2192,ULK1,,10.1016/j.cell.2020.10.038,,,, +2192,BUB1B,,10.1016/j.cell.2020.10.038,,,, +2192,BUB1,,10.1016/j.cell.2020.10.038,,,, +2192,PRKAA1,,10.1016/j.cell.2020.10.038,,,, +2192,ITK,,10.1016/j.cell.2020.10.038,,,, +2192,TNK2,,10.1016/j.cell.2020.10.038,,,, +2192,CDK17,,10.1016/j.cell.2020.10.038,,,, +2192,CDK6,,10.1016/j.cell.2020.10.038,,,, +2192,STK17A,,10.1016/j.cell.2020.10.038,,,, +2192,NLK,,10.1016/j.cell.2020.10.038,,,, +2192,CDK12,,10.1016/j.cell.2020.10.038,,,, +2192,IRAK4,,10.1016/j.cell.2020.10.038,,,, +2192,SIK2,,10.1016/j.cell.2020.10.038,,,, +2192,RIOK2,,10.1016/j.cell.2020.10.038,,,, +2192,MARK4,,10.1016/j.cell.2020.10.038,,,, +2192,AURKB,,10.1016/j.cell.2020.10.038,,,, +2192,COQ8B,,10.1016/j.cell.2020.10.038,,,, +2192,MAP4K1,,10.1016/j.cell.2020.10.038,,,, +2192,HASPIN,,10.1016/j.cell.2020.10.038,,,, +2192,STK35,,10.1016/j.cell.2020.10.038,,,, +2192,COQ8A,,10.1016/j.cell.2020.10.038,,,, +2192,MAP4K3,,10.1016/j.cell.2020.10.038,,,, +2192,PRAG1,,10.1016/j.cell.2020.10.038,,,, +2192,MARK2,,10.1016/j.cell.2020.10.038,,,, +2192,ULK3,,10.1016/j.cell.2020.10.038,,,, +2192,MAP3K21,,10.1016/j.cell.2020.10.038,,,, +2192,AAK1,,10.1016/j.cell.2020.10.038,,,, +2192,MAPK6,,10.1016/j.cell.2020.10.038,,,, +2192,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +2192,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2192,CDK10,,10.1016/j.cell.2020.10.038,,,, +2192,PDK2,,10.1016/j.cell.2020.10.038,,,, +2192,PTK2B,,10.1016/j.cell.2020.10.038,,,, +2192,CDK13,,10.1016/j.cell.2020.10.038,,,, +2192,MAPK7,,10.1016/j.cell.2020.10.038,,,, +2193,MAP3K20,,10.1016/j.cell.2020.10.038,,,, +2193,p38alpha,,10.1016/j.cell.2020.10.038,,,, +2193,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2193,CDK4,,10.1016/j.cell.2020.10.038,,,, +2193,MAST3,,10.1016/j.cell.2020.10.038,,,, +2194,FER,,10.1016/j.cell.2020.10.038,,,, +2194,MARK4,,10.1016/j.cell.2020.10.038,,,, +2194,AURKB,,10.1016/j.cell.2020.10.038,,,, +2194,ULK3,,10.1016/j.cell.2020.10.038,,,, +2194,AAK1,,10.1016/j.cell.2020.10.038,,,, +2194,MAP3K11,,10.1016/j.cell.2020.10.038,,,, +2194,RPS6KA1,,10.1016/j.cell.2020.10.038,,,, +2194,STK38,,10.1016/j.cell.2020.10.038,,,, +2194,CDK13,,10.1016/j.cell.2020.10.038,,,, +2194,PRKAA1,,10.1016/j.cell.2020.10.038,,,, +2194,ITK,,10.1016/j.cell.2020.10.038,,,, +2194,TNK2,,10.1016/j.cell.2020.10.038,,,, +2194,CDK17,,10.1016/j.cell.2020.10.038,,,, +2194,CDK5,,10.1016/j.cell.2020.10.038,,,, +2194,CDK6,,10.1016/j.cell.2020.10.038,,,, +2194,LIMK2,,10.1016/j.cell.2020.10.038,,,, +2194,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2194,BLK,,10.1016/j.cell.2020.10.038,,,, +2194,CDK9,,10.1016/j.cell.2020.10.038,,,, +2194,CDK7,,10.1016/j.cell.2020.10.038,,,, +2194,ABL2,,10.1016/j.cell.2020.10.038,,,, +2194,TEC,,10.1016/j.cell.2020.10.038,,,, +2194,Wee1,,10.1016/j.cell.2020.10.038,,,, +2194,CDK2,,10.1016/j.cell.2020.10.038,,,, +2194,Src,,10.1016/j.cell.2020.10.038,,,, +2194,CDK4,,10.1016/j.cell.2020.10.038,,,, +2194,LCK,,10.1016/j.cell.2020.10.038,,,, +2194,STK10,,10.1016/j.cell.2020.10.038,,,, +2194,ULK1,,10.1016/j.cell.2020.10.038,,,, +2194,BUB1B,,10.1016/j.cell.2020.10.038,,,, +2194,AURKA,,10.1016/j.cell.2020.10.038,,,, +2194,PLK4,,10.1016/j.cell.2020.10.038,,,, +2195,PIP4K2C,,10.1016/j.cell.2020.10.038,,N.D.,, +2195,PIP4K2B,,10.1016/j.cell.2020.10.038,,N.D.,, +2195,PIP4K2A,,10.1016/j.cell.2020.10.038,,N.D.,, +2196,PAK4,,10.1016/j.cell.2020.10.038,,,, +2196,CSNK1A1,,10.1016/j.cell.2020.10.038,,,, +2196,CSNK1D,,10.1016/j.cell.2020.10.038,,,, +2196,CSNK1E,,10.1016/j.cell.2020.10.038,,,, +2196,GSK3A,,10.1016/j.cell.2020.10.038,,,, +2196,GSK-3beta,,10.1016/j.cell.2020.10.038,,,, +2196,LIMK2,,10.1016/j.cell.2020.10.038,,,, +2196,STK4,,10.1016/j.cell.2020.10.038,,,, +2196,MAP3K1,,10.1016/j.cell.2020.10.038,,,, +2196,STK35,,10.1016/j.cell.2020.10.038,,,, +2196,MINK1,,10.1016/j.cell.2020.10.038,,,, +2196,STK17B,,10.1016/j.cell.2020.10.038,,,, +2196,STK10,,10.1016/j.cell.2020.10.038,,,, +2197,GSK3A,,10.1016/j.cell.2020.10.038,,,, +2197,STK4,,10.1016/j.cell.2020.10.038,,,, +2197,NUAK1,,10.1016/j.cell.2020.10.038,,,, +2197,PIM2,,10.1016/j.cell.2020.10.038,,,, +2197,STK17B,,10.1016/j.cell.2020.10.038,,,, +2197,CDK14,,10.1016/j.cell.2020.10.038,,,, +2197,CSNK1D,,10.1016/j.cell.2020.10.038,,,, +2197,GSK-3beta,,10.1016/j.cell.2020.10.038,,,, +2198,BLK,,10.1016/j.cell.2020.10.038,,,, +2198,STK17A,,10.1016/j.cell.2020.10.038,,,, +2198,LIMK1,,10.1016/j.cell.2020.10.038,,,, +2198,LIMK2,,10.1016/j.cell.2020.10.038,,,, +2198,TNK2,,10.1016/j.cell.2020.10.038,,,, +2199,CLK1,,10.1016/j.cell.2020.10.038,,,, +2199,CDK9,,10.1016/j.cell.2020.10.038,,,, +2200,ALK,,10.1016/j.ejmech.2021.113335,,,, +2201,ALK,0/0/4/30/47 (WB),10.1016/j.ejmech.2021.113335,,,,% ALK degradation in SR cells at 0.05/0.5/5/50/500 nM +2202,ALK,,10.1016/j.ejmech.2021.113335,,,, +2202,ALK,77.3/96.9,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2203,ALK,4/0/0/7/57 (WB),10.1016/j.ejmech.2021.113335,,,,% ALK degradation in SR cells at 0.05/0.5/5/50/500 nM +2204,ALK,0/7/0/7/49 (WB),10.1016/j.ejmech.2021.113335,,,,% ALK degradation in SR cells at 0.05/0.5/5/50/500 nM +2205,ALK,,10.1016/j.ejmech.2021.113335,,,, +2206,ALK,,10.1016/j.ejmech.2021.113335,,,, +2207,ALK,,10.1016/j.ejmech.2021.113335,,,, +2208,ALK,,10.1016/j.ejmech.2021.113335,,,, +2209,ALK,,10.1021/acs.jmedchem.1c00270,27.4/116.5,,Degradation of ALK in H3122/Karpas 299 cells after 16/48 h treatment, +2209,ALK,,10.1016/j.ejmech.2021.113335,,,, +2210,ALK,,10.1016/j.ejmech.2021.113335,,,, +2210,ALK,77.4/85.9,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in Karpas 299 cells after 24 h treatment at 100/1000 nM +2211,ALK,,10.1016/j.ejmech.2021.113335,,,, +2211,ALK,55.1/71.6,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in Karpas 299 cells after 24 h treatment at 100/1000 nM +2212,ALK,,10.1016/j.ejmech.2021.113335,,,, +2213,ALK,,10.1016/j.ejmech.2021.113335,,,, +2214,ALK,,10.1016/j.ejmech.2021.113335,,,, +2215,ALK,0/18/34/45/53 (WB),10.1016/j.ejmech.2021.113335,,,,% ALK degradation in SR cells at 0.05/0.5/5/50/500 nM +2216,ALK,,10.1016/j.ejmech.2021.113335,,,, +2217,ALK,,10.1016/j.ejmech.2021.113335,6.1,87.7,Degradation of ALK in SR cells, +2217,ALK G1202R,,10.1016/j.ejmech.2021.113335,,,, +2218,ALK,,10.1016/j.ejmech.2021.113335,,,, +2219,ALK,,10.1016/j.ejmech.2021.113335,,,, +2220,ALK,,10.1016/j.ejmech.2021.113335,,,, +2221,ALK,,10.1016/j.ejmech.2021.113335,,,, +2222,ALK G1202R,,10.1016/j.ejmech.2021.113335,200,,Degradation of ALK G1202R in 293T cells, +2222,ALK,,10.1016/j.ejmech.2021.113335,3.9,70.3,Degradation of ALK in SR cells, +2223,ALK,,10.1016/j.ejmech.2021.113335,,,, +2224,ALK,0/0/24/33/31 (WB),10.1016/j.ejmech.2021.113335,,,,DC50 of ALK in SR cells (nM) +2225,ALK,,10.1016/j.ejmech.2021.113335,,,, +2226,ALK,,10.1016/j.ejmech.2021.113335,,,, +2227,EGFR e19d,,10.1016/j.ejmech.2021.113328,,,, +2227,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,,,, +2228,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,,,, +2228,EGFR e19d,,10.1016/j.ejmech.2021.113328,,,, +2229,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,,,, +2229,EGFR e19d,,10.1016/j.ejmech.2021.113328,,,, +2230,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,,,, +2230,EGFR e19d,,10.1016/j.ejmech.2021.113328,,,, +2231,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,30-50/100,,Degradation of EGFR L858R/T790M in H1975/(Ba/F3) cells after 16 h treatment, +2231,EGFR e19d,,10.1016/j.ejmech.2021.113328,100,40,Degradation of EGFR e19d in PC9 cells after 48 h treatment, +2232,EGFR L858R/T790M,,10.1016/j.ejmech.2021.113328,<30/100,,Degradation of EGFR L858R/T790M in H1975/(Ba/F3) cells after 16 h treatment, +2232,EGFR e19d,,10.1016/j.ejmech.2021.113328,30-100,,Degradation of EGFR e19d in PC9 cells after 48 h treatment, +2233,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2234,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2235,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2236,SHP2,,10.1016/j.ejmech.2021.113341,6.02,,Degradation of SHP2 in MV4;11 cells after 12 h treatment, +2237,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2238,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2239,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2240,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2241,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2242,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2243,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2244,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2245,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2246,SHP2,,10.1016/j.ejmech.2021.113341,,,, +2247,PARP14,,10.1002/cbic.202100047,5,,Degradation of PARP14 in KYSE-270 cells after 24 h treatment, +2248,CDK12,,10.1038/s41589-021-00765-y,,,, +2249,CDK12,,10.1038/s41589-021-00765-y,,,, +2250,CDK12,,10.1038/s41589-021-00765-y,,,, +2251,CDK12,,10.1038/s41589-021-00765-y,,,, +2251,CDK12 C1039F,,10.1038/s41589-021-00765-y,,,, +2252,CDK12,,10.1038/s41589-021-00765-y,,,, +2253,CDK12,,10.1038/s41589-021-00765-y,,,, +2254,CDK12,,10.1038/s41589-021-00765-y,,,, +2255,CDK12,,10.1038/s41589-021-00765-y,,,, +2255,CDK12 C1039F,,10.1038/s41589-021-00765-y,,,, +2256,FKBP12,,10.1021/jacs.1c00990,,,, +2257,FKBP12,,10.1021/jacs.1c00990,,,, +2258,AR,,10.1021/jacs.1c00990,,,, +2259,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,8/6.9,,Degradation of FLT3-ITD in MOLM-13/MV-4-11 cells after 24 h treatment, +2260,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,7.4/9.1,,Degradation of FLT3-ITD in MOLM-13/MV-4-11 cells after 24 h treatment, +2261,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2262,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2263,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2264,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2265,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2266,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2267,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2268,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2269,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2270,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2271,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2272,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2273,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2274,FLT3-ITD,,10.1021/acs.jmedchem.1c00996,,,, +2275,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2276,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2277,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2278,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2279,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2280,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2281,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2282,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2283,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2284,WDR5,,10.1021/acs.jmedchem.1c00146,625,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2285,WDR5,,10.1021/acs.jmedchem.1c00146,116,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2286,WDR5,,10.1021/acs.jmedchem.1c00146,53,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2287,WDR5,,10.1021/acs.jmedchem.1c00146,920,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2288,WDR5,,10.1021/acs.jmedchem.1c00146,915,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2289,WDR5,,10.1021/acs.jmedchem.1c00146,,,, +2290,WDR5,,10.1021/acs.jmedchem.1c00146,,,, +2291,WDR5,,10.1021/acs.jmedchem.1c00146,,,, +2292,WDR5,,10.1021/acs.jmedchem.1c00146,,,, +2293,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2294,WDR5,,10.1021/acs.jmedchem.1c00146,1240,,Degradation of WDR5-HiBiT in MV4-11 (WDR5-HiBiT) cells after 24 h treatment, +2295,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2296,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2297,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2298,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2299,WDR5,,10.1021/acs.jmedchem.1c00146,,N.D.,, +2300,AR,0/25/63/70,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2301,AR,42/76/55/21,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2302,AR,49/84/89/97,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2303,AR,69/85/77/79,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2304,AR,28/58/79/62,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2305,AR,48/76/82/73,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2306,AR,58/83/79/76,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2307,AR,22/37/54/53,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2308,AR,42/63/84/82,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2309,AR,12/59/85/60,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2310,AR,<5/9/36/38,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2311,AR,10/22/43/48,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2312,AR,<5/23/41/32,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2313,AR,<5/<5/<5/9,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2314,AR,7/40/47/32,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2315,AR,54/77/91/73,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2316,AR,64/96/98/90,10.1021/acs.jmedchem.1c00882,0.15/5.08,,Degradation of AR in VCaP/LNCaP cells after 24 h treatment,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2317,AR,79/93/85/55,10.1021/acs.jmedchem.1c00882,0.76/1.41,,Degradation of AR in VCaP/LNCaP cells after 24 h treatment,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2318,AR,62/94/98/96,10.1021/acs.jmedchem.1c00882,0.28/8.3,,Degradation of AR in VCaP/LNCaP cells after 24 h treatment,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2319,AR,71/83/95/83,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2320,AR,65/92/96/79,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2321,AR,85/97/96/83,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2322,AR,76/97/97/96,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2323,AR,57/93/96/85,10.1021/acs.jmedchem.1c00882,0.12/1.43,,Degradation of AR in VCaP/LNCaP cells after 24 h treatment,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2324,AR,40/96/99/99,10.1021/acs.jmedchem.1c00882,0.38/3.38,,Degradation of AR in VCaP/LNCaP cells after 24 h treatment,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2325,AR,37/78/93/88,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2326,AR,30/82/97/95,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2327,AR,38/80/87/84,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2328,AR,16/56/71/51,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2329,AR,14/38/67/80,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2330,AR,15/48/73/82,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2331,AR,0/16/82/88,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2332,AR,13/30/38/57,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2333,AR,<5/19/75/90,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2334,AR,<5/30/25/39,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2335,AR,<5/15/75/80,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2336,AR,22/45/87/90,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2337,AR,6/12/33/41,10.1021/acs.jmedchem.1c00882,,,,% AR degradation in VCaP cells after 6 h treatment at 1/10/100/1000 nM +2338,BRD3,,10.1021/acs.jmedchem.1c01496,158.5,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2338,BRD4,,10.1021/acs.jmedchem.1c01496,125.89,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2338,BRD2,,10.1021/acs.jmedchem.1c01496,158.5,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2339,BRD3,,10.1021/acs.jmedchem.1c01496,199.5,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2339,BRD2,,10.1021/acs.jmedchem.1c01496,251.2,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2339,BRD4,,10.1021/acs.jmedchem.1c01496,125.89,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2340,BRD3,,10.1021/acs.jmedchem.1c01496,199.5,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2340,BRD4,,10.1021/acs.jmedchem.1c01496,39.81,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2340,BRD2,,10.1021/acs.jmedchem.1c01496,125.9,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2341,BRD3,,10.1021/acs.jmedchem.1c01496,4,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2341,BRD2,,10.1021/acs.jmedchem.1c01496,1.3,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2341,BRD4,,10.1021/acs.jmedchem.1c01496,6.31,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2342,BRD3,,10.1021/acs.jmedchem.1c01496,100,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2342,BRD4,,10.1021/acs.jmedchem.1c01496,63.1,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2342,BRD2,,10.1021/acs.jmedchem.1c01496,79.4,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2343,BRD4,,10.1021/acs.jmedchem.1c01496,31.62,,Degradation of BRD4 long in HEK293 cells after 4 h treatment, +2343,BRD3,,10.1021/acs.jmedchem.1c01496,63.1,,Degradation of BRD3 in HEK293 cells after 4 h treatment, +2343,BRD2,,10.1021/acs.jmedchem.1c01496,63.1,,Degradation of BRD2 in HEK293 cells after 4 h treatment, +2344,TTK,,10.1021/acs.jmedchem.1c01768,>1000,,Degradation of TTK in HCT-116 cells after 6 h treatment, +2345,TTK,,10.1021/acs.jmedchem.1c01768,>1000,,Degradation of TTK in HCT-116 cells after 6 h treatment, +2346,TTK,,10.1021/acs.jmedchem.1c01768,>1000,,Degradation of TTK in HCT-116 cells after 6 h treatment, +2347,TTK,,10.1021/acs.jmedchem.1c01768,>1000,,Degradation of TTK in HCT-116 cells after 6 h treatment, +2348,TTK,,10.1021/acs.jmedchem.1c01768,598.7/>1000,28/43,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2349,TTK,,10.1021/acs.jmedchem.1c01768,4.97/20.3,76/50,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2350,TTK,,10.1021/acs.jmedchem.1c01768,7.05/58.1,84/53,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2351,TTK,,10.1021/acs.jmedchem.1c01768,2.25/49.6,87/66,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2352,TTK,,10.1021/acs.jmedchem.1c01768,1.75/5.8,88/80,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2353,TTK,,10.1021/acs.jmedchem.1c01768,1.55/35,86/61,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2354,TTK,,10.1021/acs.jmedchem.1c01768,3.04/663,85/50,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2355,TTK,,10.1021/acs.jmedchem.1c01768,5.6/30.2,85/83,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2356,TTK,,10.1021/acs.jmedchem.1c01768,3.31/25.4,77/57,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2357,TTK,,10.1021/acs.jmedchem.1c01768,3.15/12.4,82/77,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2358,TTK,,10.1021/acs.jmedchem.1c01768,7.03/161,84/43,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2359,TTK,,10.1021/acs.jmedchem.1c01768,19.09/74.5,87/66,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2360,TTK,,10.1021/acs.jmedchem.1c01768,30.28/>1000,64/28,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2361,TTK,,10.1021/acs.jmedchem.1c01768,31.35/>1000,72/41,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2362,TTK,,10.1021/acs.jmedchem.1c01768,46/496,73/37,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2363,TTK,,10.1021/acs.jmedchem.1c01768,21.71/>1000,88/13,Degradation of TTK in COLO-205/HCT-116 cells after 6 h treatment, +2364,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2365,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2366,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2367,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2368,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2369,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2370,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2371,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2372,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2373,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2374,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2375,RIPK2,,10.1021/acs.jmedchem.1c01118,,,, +2376,RIPK2,,10.1021/acs.jmedchem.1c01118,0.13,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +2377,RIPK2,,10.1021/acs.jmedchem.1c01118,0.16,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +2378,RIPK2,,10.1021/acs.jmedchem.1c01118,0.1,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +2379,RIPK2,,10.1021/acs.jmedchem.1c01118,0.05,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +2380,RIPK2,,10.1021/acs.jmedchem.1c01118,0.16,,Degradation of RIPK2 in THP1 cells after 18 h treatment, +2381,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2382,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2383,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2384,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2385,BCL-xL,,10.1021/acs.jmedchem.1c00517,31.6/22.6,,Degradation of BCL-xL in MOLT-4/RS4;11 cells after 16 h treatment, +2386,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2387,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2388,BCL-xL,,10.1021/acs.jmedchem.1c00517,,,, +2389,BCL-xL,,10.1021/acs.jmedchem.1c00517,127.4/75.2,,Degradation of BCL-xL in MOLT-4/RS4;11 cells after 16 h treatment, +2390,BCL-xL,,10.1021/acs.jmedchem.1c00517,14.3/11.6,,Degradation of BCL-xL in MOLT-4/RS4;11 cells after 16 h treatment, +2391,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2392,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2393,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2394,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2395,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2396,ALK,,10.1021/acs.jmedchem.1c00373,<10,,Degradation of ALK in SR cells after 24 h treatment, +2396,FAK,,10.1021/acs.jmedchem.1c00373,<1/<1/<1,,Degradation of FAK in NCI-H2228/A549/Calu-1 cells after 16 h treatment, +2396,ALK G1202R,,10.1021/acs.jmedchem.1c00373,<100,,Degradation of ALK G1202R in 293T cells after 72 h treatment, +2396,PTK2B,,10.1021/acs.jmedchem.1c00373,<1,,Degradation of PYK2 in SR cells after 24 h treatment, +2396,PTK6,,10.1021/acs.jmedchem.1c00373,<1,,Degradation of PTK6 in MDA-MB-231 cells after 16 h treatment, +2396,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c00373,<100,,Degradation of EGFR L858R/T790M in H1975 cells after 72 h treatment, +2396,FER,,10.1021/acs.jmedchem.1c00373,<10,,Degradation of FER in SR cells after 24 h treatment, +2396,RPS6KA1,,10.1021/acs.jmedchem.1c00373,<100/<100/<100,,Degradation of RSK1 in NCI-H2228/A549/Calu-1 cells after 16 h treatment, +2397,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2398,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2399,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2400,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2401,ALK,,10.1021/acs.jmedchem.1c00373,,,, +2402,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2403,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2404,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2405,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2406,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2407,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2408,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2409,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2410,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2411,EGFR e19d,,10.1016/j.bioorg.2022.105605,7.95,98,Degradation of EGFR del19 in HCC-827 cells after 72 h treatment, +2412,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2413,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2414,EGFR e19d,,10.1016/j.bioorg.2022.105605,3.57,91,Degradation of EGFR del19 in HCC-827 cells after 72 h treatment, +2415,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2416,EGFR e19d,,10.1016/j.bioorg.2022.105605,,,, +2417,EGFR,,10.1021/acs.jmedchem.1c02221,,N.D.,, +2418,EGFR,,10.1021/acs.jmedchem.1c02221,36.51,,Degradation of EGFR in HCC-827 cells after 72 h treatment, +2419,HDAC2,,10.1021/acs.jmedchem.1c02179,,32,, +2419,HDAC1,,10.1021/acs.jmedchem.1c02179,,41,, +2419,HDAC3,,10.1021/acs.jmedchem.1c02179,,3,, +2420,HDAC1,,10.1021/acs.jmedchem.1c02179,,54,, +2420,HDAC3,,10.1021/acs.jmedchem.1c02179,,23,, +2420,HDAC2,,10.1021/acs.jmedchem.1c02179,,37,, +2421,HDAC3,,10.1021/acs.jmedchem.1c02179,,33,, +2421,HDAC1,,10.1021/acs.jmedchem.1c02179,,67,, +2421,HDAC2,,10.1021/acs.jmedchem.1c02179,,43,, +2422,HDAC3,,10.1021/acs.jmedchem.1c02179,,44,, +2422,HDAC2,,10.1021/acs.jmedchem.1c02179,,44,, +2422,HDAC1,,10.1021/acs.jmedchem.1c02179,,63,, +2423,HDAC1,,10.1021/acs.jmedchem.1c02179,,60,, +2423,HDAC3,,10.1021/acs.jmedchem.1c02179,,67,, +2423,HDAC2,,10.1021/acs.jmedchem.1c02179,,57,, +2424,HDAC3,,10.1021/acs.jmedchem.1c02179,640,59,Degradation of HDAC3 in HCT116 cells after 24 h treatment, +2424,HDAC2,,10.1021/acs.jmedchem.1c02179,4190,56,Degradation of HDAC2 in HCT116 cells after 24 h treatment, +2424,HDAC1,,10.1021/acs.jmedchem.1c02179,910,74,Degradation of HDAC1 in HCT116 cells after 24 h treatment, +2425,HDAC2,,10.1021/acs.jmedchem.1c02179,,47,, +2425,HDAC3,,10.1021/acs.jmedchem.1c02179,,39,, +2425,HDAC1,,10.1021/acs.jmedchem.1c02179,,57,, +2426,HDAC1,,10.1021/acs.jmedchem.1c02179,550,77,Degradation of HDAC1 in HCT116 cells after 24 h treatment, +2426,HDAC3,,10.1021/acs.jmedchem.1c02179,530,66,Degradation of HDAC3 in HCT116 cells after 24 h treatment, +2426,HDAC2,,10.1021/acs.jmedchem.1c02179,,52,, +2427,HDAC1,,10.1021/acs.jmedchem.1c02179,,13,, +2427,HDAC2,,10.1021/acs.jmedchem.1c02179,,6,, +2427,HDAC3,,10.1021/acs.jmedchem.1c02179,,24,, +2428,HDAC3,,10.1021/acs.jmedchem.1c02179,,44,, +2428,HDAC2,,10.1021/acs.jmedchem.1c02179,,14,, +2428,HDAC1,,10.1021/acs.jmedchem.1c02179,,29,, +2429,HDAC3,,10.1021/acs.jmedchem.1c02179,,22,, +2429,HDAC1,,10.1021/acs.jmedchem.1c02179,,6,, +2429,HDAC2,,10.1021/acs.jmedchem.1c02179,,5,, +2430,HDAC3,,10.1021/acs.jmedchem.1c02179,,N.D.,, +2430,HDAC2,,10.1021/acs.jmedchem.1c02179,,5,, +2430,HDAC1,,10.1021/acs.jmedchem.1c02179,,4,, +2431,HDAC2,,10.1021/acs.jmedchem.1c02179,,13,, +2431,HDAC3,,10.1021/acs.jmedchem.1c02179,,39,, +2431,HDAC1,,10.1021/acs.jmedchem.1c02179,,41,, +2432,HDAC2,,10.1021/acs.jmedchem.1c02179,,26,, +2432,HDAC1,,10.1021/acs.jmedchem.1c02179,,61,, +2432,HDAC3,,10.1021/acs.jmedchem.1c02179,,51,, +2433,HDAC2,,10.1021/acs.jmedchem.1c02179,,N.D.,, +2433,HDAC3,,10.1021/acs.jmedchem.1c02179,,37,, +2433,HDAC1,,10.1021/acs.jmedchem.1c02179,,11,, +2434,HDAC1,,10.1021/acs.jmedchem.1c02179,,58,, +2434,HDAC3,,10.1021/acs.jmedchem.1c02179,,63,, +2434,HDAC2,,10.1021/acs.jmedchem.1c02179,,23,, +2435,HDAC3,,10.1021/acs.jmedchem.1c02179,,3,, +2435,HDAC2,,10.1021/acs.jmedchem.1c02179,,6,, +2435,HDAC1,,10.1021/acs.jmedchem.1c02179,,6,, +2436,HDAC3,,10.1021/acs.jmedchem.1c02179,,10,, +2436,HDAC2,,10.1021/acs.jmedchem.1c02179,,15,, +2436,HDAC1,,10.1021/acs.jmedchem.1c02179,,26,, +2437,HDAC3,,10.1021/acs.jmedchem.1c02179,,23,, +2437,HDAC1,,10.1021/acs.jmedchem.1c02179,,22,, +2437,HDAC2,,10.1021/acs.jmedchem.1c02179,,15,, +2438,HDAC2,,10.1021/acs.jmedchem.1c02179,,50,, +2438,HDAC3,,10.1021/acs.jmedchem.1c02179,1380,76,Degradation of HDAC3 in HCT116 cells after 24 h treatment, +2438,HDAC1,,10.1021/acs.jmedchem.1c02179,3580,68,Degradation of HDAC1 in HCT116 cells after 24 h treatment, +2439,HDAC2,,10.1021/acs.jmedchem.1c02179,,23,, +2439,HDAC1,,10.1021/acs.jmedchem.1c02179,,45,, +2439,HDAC3,,10.1021/acs.jmedchem.1c02179,440,77,Degradation of HDAC3 in HCT116 cells after 24 h treatment, +2440,HDAC1,,10.1021/acs.jmedchem.1c02179,,53,, +2440,HDAC2,,10.1021/acs.jmedchem.1c02179,,14,, +2440,HDAC3,,10.1021/acs.jmedchem.1c02179,,27,, +2441,HDAC1,,10.1021/acs.jmedchem.1c02179,,38,, +2441,HDAC3,,10.1021/acs.jmedchem.1c02179,,15,, +2441,HDAC2,,10.1021/acs.jmedchem.1c02179,,11,, +2442,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2443,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2444,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2445,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2446,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2447,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2448,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2449,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2450,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2451,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2452,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2453,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2454,EZH2,,10.1021/acs.jmedchem.1c00460,,,, +2455,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2456,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2457,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2458,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2459,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2460,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2461,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2462,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2463,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2464,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2465,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2466,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2467,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2468,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2469,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2470,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2471,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2472,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2473,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2474,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2475,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2476,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2477,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2478,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2479,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2480,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2481,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2482,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2483,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2484,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2485,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2486,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2487,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2488,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2489,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2490,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2491,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2492,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2493,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2494,CDK9,,10.1021/acs.jmedchem.1c01350,,,, +2495,AR,,10.1021/acs.jmedchem.1c00900,1,85,Degradation of AR in VCaP cells after 24 h treatment, +2496,AR,,10.1021/acs.jmedchem.1c00900,1.1,89,Degradation of AR in VCaP cells after 24 h treatment, +2497,AR,,10.1021/acs.jmedchem.1c00900,0.2,95,Degradation of AR in VCaP cells after 24 h treatment, +2498,AR,,10.1021/acs.jmedchem.1c00900,0.6,99,Degradation of AR in VCaP cells after 24 h treatment, +2499,AR,,10.1021/acs.jmedchem.1c00900,0.7,99,Degradation of AR in VCaP cells after 24 h treatment, +2500,AR,,10.1021/acs.jmedchem.1c00900,1.5,97,Degradation of AR in VCaP cells after 24 h treatment, +2501,AR,,10.1021/acs.jmedchem.1c00900,3.2,96,Degradation of AR in VCaP cells after 24 h treatment, +2502,AR,,10.1021/acs.jmedchem.1c00900,>1000,25,Degradation of AR in VCaP cells after 24 h treatment, +2503,AR,,10.1021/acs.jmedchem.1c00900,>1000,42,Degradation of AR in VCaP cells after 24 h treatment, +2504,AR,,10.1021/acs.jmedchem.1c00900,0.8,77,Degradation of AR in VCaP cells after 24 h treatment, +2505,AR,,10.1021/acs.jmedchem.1c00900,2.7,82,Degradation of AR in VCaP cells after 24 h treatment, +2506,AR,,10.1021/acs.jmedchem.1c00900,16.2,67,Degradation of AR in VCaP cells after 24 h treatment, +2507,AR,,10.1021/acs.jmedchem.1c00900,0.9,85,Degradation of AR in VCaP cells after 24 h treatment, +2508,AR,,10.1021/acs.jmedchem.1c00900,0.2,97,Degradation of AR in VCaP cells after 24 h treatment, +2509,AR,,10.1021/acs.jmedchem.1c00900,0.3,88,Degradation of AR in VCaP cells after 24 h treatment, +2510,AR T878A,,10.1021/acs.jmedchem.1c00900,,,, +2510,AR,,10.1021/acs.jmedchem.1c00900,0.2,95,Degradation of AR in VCaP cells after 24 h treatment, +2511,AR T878A,,10.1021/acs.jmedchem.1c00900,,,, +2511,AR,,10.1021/acs.jmedchem.1c00900,0.3,92,Degradation of AR in VCaP cells after 24 h treatment, +2512,AR,,10.1021/acs.jmedchem.1c00900,0.1,76,Degradation of AR in VCaP cells after 24 h treatment, +2513,AR,,10.1021/acs.jmedchem.1c00900,>1000,20,Degradation of AR in VCaP cells after 24 h treatment, +2514,AR,,10.1021/acs.jmedchem.1c00900,>1000,45,Degradation of AR in VCaP cells after 24 h treatment, +2515,AR,,10.1021/acs.jmedchem.1c00900,>1000,54,Degradation of AR in VCaP cells after 24 h treatment, +2516,AR,,10.1021/acs.jmedchem.1c00900,>1000,19,Degradation of AR in VCaP cells after 24 h treatment, +2517,AR,,10.1021/acs.jmedchem.1c00900,>1000,35,Degradation of AR in VCaP cells after 24 h treatment, +2518,AR,,10.1021/acs.jmedchem.1c00900,0.3,78,Degradation of AR in VCaP cells after 24 h treatment, +2519,AR T878A,,10.1021/acs.jmedchem.1c00900,0.3,95,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2519,AR,,10.1021/acs.jmedchem.1c00900,0.09,99,Degradation of AR in VCaP cells after 24 h treatment, +2520,AR,,10.1021/acs.jmedchem.1c00900,0.1,99,Degradation of AR in VCaP cells after 24 h treatment, +2521,AR,,10.1021/acs.jmedchem.1c00900,1.4,88,Degradation of AR in VCaP cells after 24 h treatment, +2522,AR,,10.1021/acs.jmedchem.1c00900,1.4,93,Degradation of AR in VCaP cells after 24 h treatment, +2523,AR,,10.1021/acs.jmedchem.1c00900,0.5,96,Degradation of AR in VCaP cells after 24 h treatment, +2524,AR T878A,,10.1021/acs.jmedchem.1c00900,0.4,95,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2524,AR,,10.1021/acs.jmedchem.1c00900,0.1,96,Degradation of AR in VCaP cells after 24 h treatment, +2525,AR,,10.1021/acs.jmedchem.1c00900,0.01,99,Degradation of AR in VCaP cells after 24 h treatment, +2525,AR T878A,,10.1021/acs.jmedchem.1c00900,0.9,99,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2526,AR,,10.1021/acs.jmedchem.1c00900,0.04,99,Degradation of AR in VCaP cells after 24 h treatment, +2526,AR T878A,,10.1021/acs.jmedchem.1c00900,0.1,98,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2527,AR T878A,,10.1021/acs.jmedchem.1c00900,1.9,99,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2527,AR,,10.1021/acs.jmedchem.1c00900,0.1,100,Degradation of AR in VCaP cells after 24 h treatment, +2528,AR,,10.1021/acs.jmedchem.1c00900,0.2,96,Degradation of AR in VCaP cells after 24 h treatment, +2528,AR T878A,,10.1021/acs.jmedchem.1c00900,1.3,64,Degradation of AR T878A in LNCaP (AR T878A) cells after 24 h treatment, +2529,AR,,10.1021/acs.jmedchem.1c00900,>1000,32,Degradation of AR in VCaP cells after 24 h treatment, +2530,AR,,10.1021/acs.jmedchem.1c00900,>1000,14,Degradation of AR in VCaP cells after 24 h treatment, +2531,AR,,10.1021/acs.jmedchem.1c00900,>1000,27,Degradation of AR in VCaP cells after 24 h treatment, +2532,ALK,24.3/50.2,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2533,ALK,74.4/81.8,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2534,ALK,38.3/75.7,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2535,ALK,51.3/75.8,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2536,ALK,0/50.6,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2537,ALK,47.8/91,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2538,ALK,49.9/87,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2539,ALK,24.5/77.3,10.1021/acs.jmedchem.1c00270,,,,% ALK degradation in H3122 cells after 16 h treatment at 100/1000 nM +2540,HPGDS,,10.1021/acs.jmedchem.1c01206,,,, +2541,HPGDS,,10.1021/acs.jmedchem.1c01206,,,, +2542,HPGDS,,10.1021/acs.jmedchem.1c01206,,,, +2543,HPGDS,,10.1021/acs.jmedchem.1c01206,,,, +2544,HPGDS,,10.1021/acs.jmedchem.1c01206,0.0263/0.0173,,Degradation of HPGDS in KU812 cells after 6/24 h treatment, +2545,HPGDS,,10.1021/acs.jmedchem.1c01206,,N.D.,, +2546,HPGDS,,10.1021/acs.jmedchem.1c01206,,,, +2547,HPGDS,,10.1021/acs.jmedchem.1c01206,,N.D.,, +2548,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2548,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2548,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2549,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2549,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2549,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2550,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2550,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2550,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2551,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2551,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2551,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2552,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2552,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2552,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2553,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2553,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2553,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2554,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2554,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2554,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2555,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2555,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2555,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2556,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2556,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2556,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2557,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2557,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2557,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2558,AKT1,,10.1021/acs.jmedchem.1c01476,78,,Degradation of total AKT in BT474 cells after 24 h treatment, +2558,AKT2,,10.1021/acs.jmedchem.1c01476,78,,Degradation of total AKT in BT474 cells after 24 h treatment, +2558,AKT3,,10.1021/acs.jmedchem.1c01476,78,,Degradation of total AKT in BT474 cells after 24 h treatment, +2559,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2559,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2559,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2560,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2560,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2560,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2561,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2561,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2561,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2562,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2562,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2562,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2563,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2563,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2563,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2564,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2564,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2564,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2565,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2565,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2565,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2566,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2566,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2566,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2567,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2567,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2567,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2568,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2568,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2568,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2569,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2569,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2569,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2570,AKT2,,10.1021/acs.jmedchem.1c01476,32,,Degradation of total AKT in BT474 cells after 24 h treatment, +2570,AKT1,,10.1021/acs.jmedchem.1c01476,32,,Degradation of total AKT in BT474 cells after 24 h treatment, +2570,AKT3,,10.1021/acs.jmedchem.1c01476,32,,Degradation of total AKT in BT474 cells after 24 h treatment, +2571,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2571,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2571,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2572,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2572,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2572,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2573,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2573,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2573,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2574,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2574,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2574,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2575,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2575,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2575,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2576,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2576,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2576,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2577,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2577,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2577,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2578,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2578,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2578,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2579,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2579,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2579,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2580,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2580,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2580,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2581,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2581,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2581,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2582,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2582,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2582,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2583,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2583,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2583,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2584,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2584,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2584,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2585,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2585,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2585,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2586,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2586,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2586,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2587,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2587,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2587,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2588,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2588,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2588,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2589,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2589,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2589,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2590,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2590,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2590,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2591,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2591,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2591,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2592,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2592,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2592,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2593,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2593,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2593,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2594,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2594,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2594,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2595,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2595,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2595,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2596,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2596,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2596,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2597,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2597,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2597,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2598,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2598,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2598,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2599,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2599,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2599,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2600,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2600,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2600,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2601,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2601,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2601,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2602,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2602,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2602,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2603,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2603,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2603,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2604,AKT1,,10.1021/acs.jmedchem.1c01476,,,, +2604,AKT2,,10.1021/acs.jmedchem.1c01476,,,, +2604,AKT3,,10.1021/acs.jmedchem.1c01476,,,, +2605,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2605,EGFR e19d,,10.1021/acs.jmedchem.1c01827,,,, +2606,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2606,EGFR e19d,<20/25,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2607,EGFR e19d,<20/24,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2607,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2608,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2608,EGFR e19d,<20/25,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2609,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2609,EGFR e19d,<20/30,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2610,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2610,EGFR e19d,28/34,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2611,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2611,EGFR e19d,23/25,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2612,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2612,EGFR e19d,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2613,EGFR L858R/T790M,39/59,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2613,EGFR e19d,42/57,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2614,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c01827,,,, +2614,EGFR e19d,,10.1021/acs.jmedchem.1c01827,,,, +2615,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c01827,,,, +2615,EGFR e19d,,10.1021/acs.jmedchem.1c01827,,,, +2616,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c01827,,,, +2616,EGFR e19d,,10.1021/acs.jmedchem.1c01827,,,, +2617,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c01827,,,, +2617,EGFR e19d,,10.1021/acs.jmedchem.1c01827,,,, +2618,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 100/1000 nM +2618,EGFR e19d,<20/26,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 100/1000 nM +2619,EGFR L858R/T790M,38/79,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2619,EGFR e19d,65/81,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2620,EGFR L858R/T790M,49/69,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2620,EGFR e19d,62/70,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2621,EGFR L858R/T790M,47/74,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2621,EGFR e19d,69/78,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2622,EGFR L858R/T790M,<20/23,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2622,EGFR e19d,46/60,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2623,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2623,EGFR e19d,63/77,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2624,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2624,EGFR e19d,50/57,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2625,EGFR L858R/T790M,,10.1021/acs.jmedchem.1c01827,1.56,86,Degradation of EGFR L858R/T790M in H1975 cells after 48 h treatment, +2625,EGFR e19d,,10.1021/acs.jmedchem.1c01827,0.49,82,Degradation of EGFR e19d in HCC827 cells after 24 h treatment, +2626,EGFR e19d,69/72,10.1021/acs.jmedchem.1c01827,,,,% EGFR del19 degradation in HCC827 cells after 24 h treatment at 3/30 nM +2626,EGFR L858R/T790M,<20/<20,10.1021/acs.jmedchem.1c01827,,,,% EGFR L858R/T790M degradation in H1975 cells after 24 h treatment at 10/100 nM +2627,SOS1,5.8/30.4,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2628,SOS1,30.7/79.9,10.1021/acs.jmedchem.1c01774,216.4,,Degradation of SOS1 in NCI-H358 cells after 24 h treatment,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2629,SOS1,27.6/80.9,10.1021/acs.jmedchem.1c01774,150.3,,Degradation of SOS1 in NCI-H358 cells after 24 h treatment,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2630,SOS1,,10.1021/acs.jmedchem.1c01774,104/125/22,,Degradation of SOS1 in SK-LU-1/SW620/A549 cells after 24 h treatment, +2630,SOS1,,10.1021/acs.jmedchem.1c01774,98.4/255/119,,Degradation of SOS1 in NCI-H358/MIA PaCa2/AsPC-1 cells after 24 h treatment, +2631,SOS1,38.5/82,10.1021/acs.jmedchem.1c01774,182.1,,Degradation of SOS1 in NCI-H358 cells after 24 h treatment,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2632,SOS1,31.7/63.2,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2633,SOS1,33/49,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2634,SOS1,23.3/24.4,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2635,SOS1,4.4/14,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2636,SOS1,15.4/36.6,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2637,SOS1,0/18.3,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2638,SOS1,8/12.7,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2639,SOS1,3.2/0,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2640,SOS1,13/43.3,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2641,SOS1,18.1/9.4,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2642,SOS1,7/11.2,10.1021/acs.jmedchem.1c01774,,,,% SOS1 degradation in NCI-H358 cells after 24 h treatment at 100/1000 nM +2643,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2643,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2643,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2644,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2644,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2644,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2645,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2645,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2645,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2646,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2646,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2646,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2647,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2647,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2647,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2648,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2648,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2648,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2649,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2649,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2649,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2650,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2650,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2650,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2651,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2651,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2651,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2652,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2652,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2652,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2653,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2653,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2653,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2654,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2654,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2654,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2655,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2655,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2655,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2656,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2656,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2656,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2657,BRD3,,10.1016/j.ejmech.2022.114259,,,, +2657,BRD4,,10.1016/j.ejmech.2022.114259,,,, +2657,BRD2,,10.1016/j.ejmech.2022.114259,,,, +2658,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2659,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2660,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2661,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2662,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2663,eIF4E,,10.1016/j.ejmech.2021.113435,,N.D.,, +2664,TYR,,10.1016/j.ejmech.2021.113850,,N.D.,, +2665,TYR,,10.1016/j.ejmech.2021.113850,,N.D.,, +2666,TYR,,10.1016/j.ejmech.2021.113850,,N.D.,, +2667,TYR,,10.1016/j.ejmech.2021.113850,,N.D.,, +2668,TYR,,10.1016/j.ejmech.2021.113850,,,, +2669,TYR,,10.1016/j.ejmech.2021.113850,,,, +2670,TYR,,10.1016/j.ejmech.2021.113850,,,, +2671,TYR,,10.1016/j.ejmech.2021.113850,,,, +2672,TYR,,10.1016/j.ejmech.2021.113850,50000,61,Degradation of TYR in A375 cells after 24 h treatment, +2673,TYR,,10.1016/j.ejmech.2021.113850,,,, +2674,TYR,,10.1016/j.ejmech.2021.113850,,,, +2675,TYR,,10.1016/j.ejmech.2021.113850,,,, +2676,TYR,,10.1016/j.ejmech.2021.113850,,,, +2677,TYR,,10.1016/j.ejmech.2021.113850,,,, +2678,CDK2,,10.1016/j.ejmech.2021.113849,,,, +2679,CDK2,,10.1016/j.ejmech.2021.113849,100,,Degradation of CDK2 in HEI-OC1 cells after 24 h treatment, +2680,CDK2,,10.1016/j.ejmech.2021.113849,,,, +2681,CDK2,,10.1016/j.ejmech.2021.113849,,,, +2682,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2683,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2684,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2685,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2686,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2687,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2688,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2689,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2690,BRD4,,10.1016/j.ejmech.2021.113922,<1/<1,>99/>99,Degradation of BRD4 in 22Rv1/VCaP cells after 24 h treatment, +2691,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2692,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2693,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2694,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2695,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2696,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2697,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2698,BRD4,,10.1016/j.ejmech.2021.113922,,,, +2699,BCR-ABL,,10.1016/j.ejmech.2021.113645,8.7,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2700,BCR-ABL,,10.1016/j.ejmech.2021.113645,17.5,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2701,BCR-ABL,,10.1016/j.ejmech.2021.113645,18.4,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2702,BCR-ABL,,10.1016/j.ejmech.2021.113645,26.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2703,BCR-ABL,,10.1016/j.ejmech.2021.113645,10.8,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2704,BCR-ABL,,10.1016/j.ejmech.2021.113645,7.8,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2705,BCR-ABL,,10.1016/j.ejmech.2021.113645,11,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2706,BCR-ABL,,10.1016/j.ejmech.2021.113645,9,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2707,BCR-ABL,,10.1016/j.ejmech.2021.113645,5.6,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2708,BCR-ABL,,10.1016/j.ejmech.2021.113645,10,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2709,BCR-ABL,,10.1016/j.ejmech.2021.113645,11.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2710,BCR-ABL,,10.1016/j.ejmech.2021.113645,95.4,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2711,BCR-ABL,,10.1016/j.ejmech.2021.113645,245.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2712,BCR-ABL T315A,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL F317V,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL F317L,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL V299L,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL E255V,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL G250E,,10.1016/j.ejmech.2021.113645,,,, +2712,BCR-ABL,,10.1016/j.ejmech.2021.113645,0.18,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2713,BCR-ABL,,10.1016/j.ejmech.2021.113645,8.9,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2714,BCR-ABL,,10.1016/j.ejmech.2021.113645,2.7,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2715,BCR-ABL,,10.1016/j.ejmech.2021.113645,2.7,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2716,BCR-ABL,,10.1016/j.ejmech.2021.113645,10.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2717,BCR-ABL,,10.1016/j.ejmech.2021.113645,11.1,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2718,BCR-ABL,,10.1016/j.ejmech.2021.113645,125,,Degradation of BCR-ABL in K562 cells after 16 h treatment, +2719,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2720,HSP90,,10.1016/j.ejmech.2021.114013,990,83.43,Degradation of HSP90 in MCF-7 cells after 6 h treatment, +2721,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2722,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2723,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2724,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2725,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2726,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2727,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2728,HSP90,,10.1016/j.ejmech.2021.114013,,,, +2729,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2730,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2731,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2732,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2733,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2734,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2735,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2736,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2737,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2738,HSP90,,10.1016/j.ejmech.2021.114013,,N.D.,, +2739,CDK12,,10.1016/j.ejmech.2021.114012,,,, +2740,CDK12,,10.1016/j.ejmech.2021.114012,416/412,,Degradation of CDK12 in Bel-7402/MDA-MB-231 cells after 24 h treatment, +2741,CDK12,,10.1016/j.ejmech.2021.114012,,,, +2742,CDK12,,10.1016/j.ejmech.2021.114012,,,, +2743,GSK-3beta,<5/0,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2743,GSK3A,<5/0,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2744,GSK3A,<5/<5,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2744,GSK-3beta,<5/35.8,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2745,GSK-3beta,14.5/37.3,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2745,GSK3A,38.7/76.4,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2746,GSK3A,<5/<5,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2746,GSK-3beta,<5/<5,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2747,GSK-3beta,<5/<5,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2747,GSK3A,<5/<5,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2748,GSK-3beta,30.5/39.6,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2748,GSK3A,46.9/68.9,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2749,GSK-3beta,29.9/46.6,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2749,GSK3A,45.4/75.6,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2750,GSK3A,42.0/79.5,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2750,GSK-3beta,25.7/65,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2751,GSK-3beta,28.9/63.8,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2751,GSK3A,47.4/77.2,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2752,GSK-3beta,15.2/61.3,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2752,GSK3A,29.7/75.4,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2753,GSK-3beta,41.9/79.5,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2753,GSK3A,61.1/95.2,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2754,GSK3A,65.0/90.7,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2754,GSK-3beta,51.6/79.1,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2755,GSK-3beta,55.9/83.1,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2755,GSK3A,63.8/91.8,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2756,GSK-3beta,61.6/81.3,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2756,GSK3A,68.1/87.8,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2757,GSK-3beta,55.9/86,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2757,GSK3A,66.3/93.9,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2758,GSK-3beta,38.2/88.3,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2758,GSK3A,70.9/95.1,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2759,GSK-3beta,54.6/89.7,10.1016/j.ejmech.2021.113889,,,,% GSK3B degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2759,GSK3A,69.3/93.8,10.1016/j.ejmech.2021.113889,,,,% GSK3A degradation in SH-SY5Y cells after 24 h treatment at 1000/10000 nM +2760,GSK-3beta,,10.1016/j.ejmech.2021.113889,110.1,,Degradation of GSK3B in SH-SY5Y cells after 24 h treatment, +2760,GSK3A,,10.1016/j.ejmech.2021.113889,38.2,,Degradation of GSK3A in SH-SY5Y cells after 24 h treatment, +2761,GSK3A,,10.1016/j.ejmech.2021.113889,28.3,,Degradation of GSK3A in SH-SY5Y cells after 24 h treatment, +2761,GSK-3beta,,10.1016/j.ejmech.2021.113889,34.2,,Degradation of GSK3B in SH-SY5Y cells after 24 h treatment, +2762,GSK3A,,10.1016/j.ejmech.2021.113889,40.4,,Degradation of GSK3A in SH-SY5Y cells after 24 h treatment, +2762,GSK-3beta,,10.1016/j.ejmech.2021.113889,66.6,,Degradation of GSK3B in SH-SY5Y cells after 24 h treatment, +2763,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2763,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2764,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2764,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2765,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2765,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2766,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2766,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2767,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2767,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2768,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2768,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2769,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2769,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2770,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2770,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2771,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2771,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2772,GSK-3beta,,10.1016/j.ejmech.2021.113889,,,, +2772,GSK3A,,10.1016/j.ejmech.2021.113889,,,, +2773,AXL,,10.1016/j.ejmech.2022.114253,,,, +2774,AXL,,10.1016/j.ejmech.2022.114253,,,, +2775,AXL,,10.1016/j.ejmech.2022.114253,,,, +2776,AXL,,10.1016/j.ejmech.2022.114253,,,, +2777,AXL,,10.1016/j.ejmech.2022.114253,,,, +2778,AXL,,10.1016/j.ejmech.2022.114253,,,, +2779,AXL,,10.1016/j.ejmech.2022.114253,,,, +2780,AXL,,10.1016/j.ejmech.2022.114253,,,, +2781,AXL,,10.1016/j.ejmech.2022.114253,,,, +2782,AXL,,10.1016/j.ejmech.2022.114253,,,, +2783,AXL,,10.1016/j.ejmech.2022.114253,,,, +2784,AXL,,10.1016/j.ejmech.2022.114253,,,, +2785,AXL,,10.1016/j.ejmech.2022.114253,,,, +2786,AXL,,10.1016/j.ejmech.2022.114253,,,, +2787,AXL,,10.1016/j.ejmech.2022.114253,,,, +2788,AXL,,10.1016/j.ejmech.2022.114253,,,, +2789,AXL,,10.1016/j.ejmech.2022.114253,,,, +2790,AXL,,10.1016/j.ejmech.2022.114253,,,, +2791,AXL,,10.1016/j.ejmech.2022.114253,,,, +2792,AXL,,10.1016/j.ejmech.2022.114253,,,, +2793,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2794,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2795,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2796,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2797,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2798,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2799,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2800,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2801,MDM2,,10.1016/j.ejmech.2021.113425,4.1,,Degradation of MDM2 in RS4;11 cells after 12 h treatment, +2802,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2803,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2804,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2805,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2806,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2807,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2808,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2809,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2810,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2811,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2812,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2813,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2814,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2815,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2816,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2817,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2818,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2819,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2820,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2821,MDM2,,10.1016/j.ejmech.2021.113425,,,, +2822,MDM2,32/81 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2823,MDM2,0/0 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2824,MDM2,91/92 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2825,MDM2,0/0 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2826,MDM2,0/0 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2827,MDM2,31/74 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2828,MDM2,11/84 (WB),10.1016/j.ejmech.2021.113425,,,,% MDM2 degradation in RS4;11 cells at 10/100 nM +2829,KRAS G12C,,10.1016/j.ejmech.2021.114088,3610/4530,,Degradation of KRAS G12C in H358/H23 cells after 24 h treatment, +2830,BTK,0/13.5 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2830,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2831,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2831,BTK,25.8/69.6 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2832,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2832,BTK,33/35 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2833,BTK,,10.1016/j.ejmech.2021.113820,28.5,67.1,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2833,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2834,BTK C481S,,10.1016/j.ejmech.2021.113820,52.7,68.6,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2834,BTK,,10.1016/j.ejmech.2021.113820,9.4,66.5,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2835,BTK C481S,,10.1016/j.ejmech.2021.113820,80.4,88.4,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2835,BTK,,10.1016/j.ejmech.2021.113820,8.1,72.4,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2836,BTK C481S,,10.1016/j.ejmech.2021.113820,52.3,84.8,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2836,BTK,,10.1016/j.ejmech.2021.113820,8.3,92.4,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2837,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2837,BTK,22.8/33.8 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2838,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2838,BTK,7/0 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2839,BTK C481S,,10.1016/j.ejmech.2021.113820,,,, +2839,BTK,22/6 (WB),10.1016/j.ejmech.2021.113820,,,,% BTK degradation in JeKo-1 cells at 100/1000 nM +2840,BTK,,10.1016/j.ejmech.2021.113820,32.3,76.9,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2840,BTK C481S,,10.1016/j.ejmech.2021.113820,30.1,84.3,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2841,BTK,,10.1016/j.ejmech.2021.113820,12.1,78,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2841,BTK C481S,,10.1016/j.ejmech.2021.113820,37.9,83.5,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2842,BTK,,10.1016/j.ejmech.2021.113820,41.9,93,Degradation of BTK in JeKo-1 cells after 24 h treatment, +2842,BTK C481S,,10.1016/j.ejmech.2021.113820,42.9,90.7,Degradation of BTK C481S in TMD8 cells after 24 h treatment, +2843,HDAC6,,10.1021/acschembio.1c00681,108.9,88,Degradation of HDAC6 in K562 cells after 8 h treatment, +2844,HDAC6,,10.1021/acschembio.1c00681,,25,, +2845,HDAC6,,10.1021/acschembio.1c00681,,6.3,, +2846,HDAC6,,10.1021/acschembio.1c00681,,17,, +2847,HDAC6,,10.1021/acschembio.1c00681,,42,, +2848,JAK3,72 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2848,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +2848,JAK2,77 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK2 degradation in MHH-CALL-4 cells at 100 nM +2849,JAK2,40 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK2 degradation in MHH-CALL-4 cells at 100 nM +2849,JAK3,29 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2850,JAK2,,10.1021/acsmedchemlett.1c00650,21,,Degradation of JAK2 in MHH-CALL-4 cells after 24 h treatment, +2850,JAK3,61 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2851,JAK2,77 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK2 degradation in MHH-CALL-4 cells at 100 nM +2851,JAK3,58 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2851,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +2852,JAK2,,10.1021/acsmedchemlett.1c00650,14,,Degradation of JAK2 in MHH-CALL-4 cells after 24 h treatment, +2852,JAK3,43 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2853,JAK2,,10.1021/acsmedchemlett.1c00650,17,,Degradation of JAK2 in MHH-CALL-4 cells after 24 h treatment, +2853,JAK3,,10.1021/acsmedchemlett.1c00650,,,, +2854,JAK2,72 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK2 degradation in MHH-CALL-4 cells at 100 nM +2854,JAK3,54 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2855,JAK2,,10.1021/acsmedchemlett.1c00650,26,,Degradation of JAK2 in MHH-CALL-4 cells after 24 h treatment, +2855,JAK3,42 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2856,JAK2,1/32/69/19 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK2 degradation in MHH-CALL-4 cells at 1/10/100/1000 nM +2856,JAK3,72 (WB),10.1021/acsmedchemlett.1c00650,,,,% JAK3 degradation in MHH-CALL-4 cells at 100 nM +2857,JAK3,,10.1021/acsmedchemlett.1c00650,11,92,Degradation of JAK3 in PDX SJBALL020589 cells after 24 h treatment, +2857,JAK2,,10.1021/acsmedchemlett.1c00650,14/24,90/82,Degradation of JAK2 in PDX SJBALL020589/MHH-CALL-4 cells after 24 h treatment, +2857,JAK2 R683G,,10.1021/acsmedchemlett.1c00650,74,,Degradation of JAK2 R683G in KOPN49 cells after 24 h treatment, +2858,JAK2,,10.1021/acsmedchemlett.1c00650,,,, +2858,JAK3,,10.1021/acsmedchemlett.1c00650,,,, +2859,JAK2,,10.1021/acsmedchemlett.1c00650,,,, +2859,JAK3,,10.1021/acsmedchemlett.1c00650,,,, +2860,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2861,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2862,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2863,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2864,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2865,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2866,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2867,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,8,,Degradation of EGFR del19/T790M/C797S in Ba/F3 cells after 3 h treatment, +2867,EGFR e19d,0/30/30/53/29 (WB),10.1021/acsmedchemlett.1c00645,,,,% EGFR del19 degradation in HCC827 cells at 5/10/50/100/500 nM +2867,EGFR L858R/T790M,10/7/7/27/34 (WB),10.1021/acsmedchemlett.1c00645,,,,% EGFR EGFR L858R/T790M degradation in H1975 cells at 5/10/50/100/500 nM +2868,EGFR del19/T790M/C797S,,10.1021/acsmedchemlett.1c00645,,,, +2869,STAT3,,10.1021/acsmedchemlett.1c00155,120/17/1200,,Degradation of STAT3 in MOLM-16/SU-DHL-1/SUP-M2 cells after 4/14/14 h treatment, +2870,FGFR2,,10.1002/anie.202101328,,,, +2871,FGFR2,,10.1002/anie.202101328,,,, +2872,FGFR2,,10.1002/anie.202101328,,,, +2873,FGFR2,,10.1002/anie.202101328,,,, +2874,FGFR2,,10.1002/anie.202101328,,,, +2875,FGFR2,,10.1002/anie.202101328,,,, +2876,FGFR2,,10.1002/anie.202101328,,,, +2877,FGFR2,,10.1002/anie.202101328,,,, +2878,FGFR2,,10.1002/anie.202101328,70,74,Degradation of FGFR2 in KATO III cells after 6 h treatment, +2878,FGFR1,,10.1002/anie.202101328,4.35,85,Degradation of FGFR1 in CCLP1 cells after 16 h treatment, +2879,FGFR2,,10.1002/anie.202101328,,,, +2880,FGFR2,,10.1002/anie.202101328,,,, +2881,FGFR2,,10.1002/anie.202101328,,,, +2882,FGFR2,,10.1002/anie.202101328,,,, +2883,FGFR2,,10.1002/anie.202101328,,,, +2884,FGFR2,,10.1002/anie.202101328,,,, +2885,FGFR2,,10.1002/anie.202101328,,,, +2886,CCR9,,10.1002/anie.202116782,,,, +2887,FAK,,10.1002/anie.202109237,125.9,,Degradation of FAK in A549 cells after 24 h treatment, +2888,FAK,,10.1002/anie.202109237,20,,Degradation of FAK in A549 cells after 24 h treatment, +2889,FAK,,10.1002/anie.202109237,158.5,,Degradation of FAK in A549 cells after 24 h treatment, +2890,FAK,,10.1002/anie.202109237,31.6,,Degradation of FAK in A549 cells after 24 h treatment, +2891,FAK,,10.1002/anie.202109237,39.8,,Degradation of FAK in A549 cells after 24 h treatment, +2892,FAK,,10.1002/anie.202109237,4,,Degradation of FAK in A549 cells after 24 h treatment, +2893,BRD4,,10.1002/anie.202108848,,,, +2893,BRD2,,10.1002/anie.202108848,,,, +2894,BRD4,,10.1002/anie.202108848,,,, +2894,BRD2,,10.1002/anie.202108848,,,, +2895,BRD2,,10.1002/anie.202108848,,,, +2895,BRD4,,10.1002/anie.202108848,,,, +2896,BRD4,,10.1002/anie.202108848,,,, +2896,BRD2,,10.1002/anie.202108848,,,, +2897,BRD2,,10.1002/anie.202108848,,,, +2897,BRD4,,10.1002/anie.202108848,,,, +2898,BRD4,,10.1002/anie.202108848,0.87/0.16,,Degradation of BRD4 in MV4-11 cells after 12/24 h treatment, +2898,BRD2,,10.1002/anie.202108848,,,, +2898,BRD4,,10.1002/anie.202108848,24,,Degradation of BRD4 in HD-MB03 cells after 12 h treatment, +2899,BRD2,,10.1002/anie.202108848,,,, +2899,BRD4,,10.1002/anie.202108848,,,, +2900,BRD2,,10.1002/anie.202108848,,,, +2900,BRD4,,10.1002/anie.202108848,,,, +2901,MIF,0/16,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2902,MIF,0/31,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2903,MIF,0/22,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2904,MIF,0/50,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2905,MIF,0/58,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2906,MIF,0/0,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2907,MIF,0/61,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2908,MIF,21/51,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2909,MIF,,10.1002/anie.202101864,1500,,Degradation of MIF in A549 cells after 12 h treatment, +2910,MIF,55/61,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2911,MIF,0/40,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2912,MIF,0/38,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2913,MIF,,10.1002/anie.202101864,100,90-95,Degradation of MIF in A549 cells after 12 h treatment, +2914,MIF,51/64,10.1002/anie.202101864,,,,% MIF degradation in A549 cells after 12 h treatment at 2000/20000 nM +2915,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2916,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2917,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2918,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2919,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2920,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2921,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2922,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2923,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2924,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2925,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2926,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2927,PI3Kalpha,,10.1016/j.bmc.2022.116707,,,, +2928,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2928,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2928,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2928,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2929,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2929,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2929,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2929,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2930,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2930,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2930,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2930,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2931,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2931,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2931,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2931,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2932,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2932,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2932,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2932,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2933,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2933,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2933,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2933,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2934,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2934,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2934,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2934,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2935,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2935,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2935,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2935,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2936,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2936,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2936,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2936,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2937,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2937,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2937,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2937,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2938,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2938,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2938,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2938,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2939,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2939,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2939,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2939,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2940,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2940,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2940,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2940,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2941,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2941,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2941,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2941,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2942,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2942,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2942,FLT3-ITD,,10.1016/j.bioorg.2021.105508,76.7,,Degradation of FLT3-ITD in BaF3 FLT3-ITD cells after 24 h treatment, +2942,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2943,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2943,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2943,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2943,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2944,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2944,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2944,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2944,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2945,FLT3-ITD,,10.1016/j.bioorg.2021.105508,,,, +2945,FLT3-ITD-F691L,,10.1016/j.bioorg.2021.105508,,,, +2945,FLT3,,10.1016/j.bioorg.2021.105508,,,, +2945,FLT3-ITD-D835V,,10.1016/j.bioorg.2021.105508,,,, +2946,MYC,,10.1016/j.bioorg.2021.105505,,,, +2947,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2948,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2949,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2950,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2951,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2952,MDM2,,10.1016/j.bioorg.2021.104901,,,, +2953,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2954,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2955,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2956,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2957,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2958,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2959,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2960,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2961,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2962,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2963,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2964,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2965,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2966,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2967,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2968,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2969,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2970,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2971,PD-L1,,10.1016/j.bioorg.2021.104833,,,, +2972,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2973,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2974,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2975,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2976,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2977,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2978,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2979,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2980,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2981,KRAS G12C,,10.1016/j.bioorg.2021.105447,,N.D.,, +2982,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2983,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2984,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2985,KRAS G12C,,10.1016/j.bioorg.2021.105447,1250/2500,,Degradation of KRAS G12C in NCI-H358/NCI-H23 cells after 48 h treatment, +2986,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2987,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2988,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2989,KRAS G12C,,10.1016/j.bioorg.2021.105447,,,, +2990,SHP2,,10.1021/acs.biochem.1c00377,,N.D.,, +2991,SHP2,,10.1021/acs.biochem.1c00377,,N.D.,, +2992,SHP2,,10.1021/acs.biochem.1c00377,,N.D.,, +2993,SHP2,,10.1021/acs.biochem.1c00377,,N.D.,, +2994,SHP2,,10.1021/acs.biochem.1c00377,,,, +2994,SHP2 F285S,,10.1021/acs.biochem.1c00377,,,, +2995,SHP2 F285S,,10.1021/acs.biochem.1c00377,,,, +2995,SHP2,,10.1021/acs.biochem.1c00377,,,, +2996,SHP2,,10.1021/acs.biochem.1c00377,,,, +2996,SHP2 F285S,,10.1021/acs.biochem.1c00377,,,, +2997,Wee1,,10.1016/j.bmcl.2022.128636,,,, +2998,Wee1,,10.1016/j.bmcl.2022.128636,,,, +2999,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3000,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3001,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3002,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3003,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3004,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3005,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3006,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3007,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3008,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3009,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3010,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3011,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3012,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3013,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3014,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3015,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3016,Wee1,,10.1016/j.bmcl.2022.128636,,,, +3017,AR-V7,,10.1016/j.bmcl.2021.128448,,N.D.,, +3018,AR-V7,,10.1016/j.bmcl.2021.128448,350,53,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3019,AR-V7,,10.1016/j.bmcl.2021.128448,,N.D.,, +3020,AR-V7,,10.1016/j.bmcl.2021.128448,,N.D.,, +3021,AR-V7,,10.1016/j.bmcl.2021.128448,320,67,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3022,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3023,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3024,AR-V7,,10.1016/j.bmcl.2021.128448,>10000,,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3025,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3026,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3027,AR-V7,,10.1016/j.bmcl.2021.128448,>10000,,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3028,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3029,AR-V7,,10.1016/j.bmcl.2021.128448,>10000,,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3030,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3031,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3032,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3033,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3034,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3035,AR-V7,,10.1016/j.bmcl.2021.128448,>10000,,Degradation of AR-V7 in 22RV1 cells after 24 h treatment, +3036,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3037,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3038,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3039,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3040,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3041,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3042,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3043,AR-V7,,10.1016/j.bmcl.2021.128448,,,, +3044,TACC3,,10.1111/cas.13198,,,, +3045,TACC3,,10.1111/cas.13198,,,, +3046,TACC3,,10.1111/cas.13198,,,, +3047,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3048,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3049,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3050,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3051,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3052,FGFR3-TACC3,,10.1016/j.bmcl.2022.128584,,,, +3053,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3054,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3055,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3056,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3057,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3058,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3059,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3060,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3061,AR,>=50/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3062,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3063,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3064,AR,>=90/>=90,10.1021/acsmedchemlett.1c00498,,,,% AR degradation in Vcap cells after 24 h treatment at 10/100 nM +3065,IRAK1,,10.1021/acsmedchemlett.1c00244,16,95,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3066,IRAK1,,10.1021/acsmedchemlett.1c00244,3,96,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3067,IRAK1,,10.1021/acsmedchemlett.1c00244,16,97,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3068,IRAK1,,10.1021/acsmedchemlett.1c00244,9,90,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3069,IRAK1,,10.1021/acsmedchemlett.1c00244,13,96,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3070,IRAK1,,10.1021/acsmedchemlett.1c00244,13,94,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3071,IRAK1,,10.1021/acsmedchemlett.1c00244,21,96,Degradation of IRAK1 in HEK293T cells after 24 h treatment, +3072,IRAK1,,10.1021/acsmedchemlett.1c00244,,95,, +3073,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3074,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3075,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3076,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3077,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3078,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3079,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3080,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3081,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3082,JAK2,,10.1021/acsmedchemlett.1c00245,,,, +3083,BTK,,10.1021/acsmedchemlett.1c00178,68,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3084,BTK,,10.1021/acsmedchemlett.1c00178,78,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3085,BTK,,10.1021/acsmedchemlett.1c00178,78,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3086,BTK,,10.1021/acsmedchemlett.1c00178,107,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3087,BTK,,10.1021/acsmedchemlett.1c00178,34,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3088,BTK,,10.1021/acsmedchemlett.1c00178,74,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3089,BTK,,10.1021/acsmedchemlett.1c00178,28,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3090,BTK,,10.1021/acsmedchemlett.1c00178,2.9,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3091,BTK,,10.1021/acsmedchemlett.1c00178,35,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3092,BTK,,10.1021/acsmedchemlett.1c00178,17,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3093,BTK,,10.1021/acsmedchemlett.1c00178,35,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3094,BTK,,10.1021/acsmedchemlett.1c00178,7.2,,Degradation of BTK in Ramos cells after 16 h treatment by ELISA assay, +3095,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3096,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3097,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3098,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3099,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3100,BRD9,,10.1021/acsmedchemlett.1c00580,1,,Degradation of BRD9 in HEK293A cells after 24 h treatment, +3101,SMARCA2,,10.1021/acsmedchemlett.1c00657,4,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3102,SMARCA2,,10.1021/acsmedchemlett.1c00657,2,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3103,SMARCA2,,10.1021/acsmedchemlett.1c00657,2,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3104,SMARCA2,,10.1021/acsmedchemlett.1c00657,3,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3105,SMARCA2,,10.1021/acsmedchemlett.1c00657,3,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3106,SMARCA2,,10.1021/acsmedchemlett.1c00657,3,,Degradation of SMARCA2 HiBiT in HT1080 cells after 6 h treatment, +3107,BRAF V600E,,10.1021/acsmedchemlett.2c00039,26,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3108,BRAF V600E,,10.1021/acsmedchemlett.2c00039,10,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3109,BRAF V600E,,10.1021/acsmedchemlett.2c00039,10,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3110,BRAF V600E,,10.1021/acsmedchemlett.2c00039,20,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3111,BRAF V600E,,10.1021/acsmedchemlett.2c00039,23,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3112,BRAF V600E,,10.1021/acsmedchemlett.2c00039,16,,Degradation of BRAF V600E in A375 cells after 24 h treatment, +3113,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3114,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3115,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3116,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3117,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3118,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3119,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3120,MDM2,,10.1016/j.apsb.2020.11.022,1010,>95,Degradation of MDM2 in A549 cells after 24 h treatment, +3121,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3122,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3123,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3124,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3125,MDM2,,10.1016/j.apsb.2020.11.022,,,, +3126,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3127,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3128,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3129,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3130,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3131,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3132,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3133,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3134,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3135,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3136,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3137,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3138,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3139,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,108.7,,Degradation of BCR-ABL T315I in Ba/F3 cells after 24 h treatment, +3140,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3141,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3142,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3143,BCR-ABL T315I,,10.1016/j.apsb.2020.11.009,,,, +3144,HMGCR,,10.1016/j.apsb.2020.11.001,,,, +3145,HMGCR,,10.1016/j.apsb.2020.11.001,,,, +3146,HMGCR,,10.1016/j.apsb.2020.11.001,,,, +3147,HMGCR,,10.1016/j.apsb.2020.11.001,,,, +3148,HMGCR,,10.1016/j.apsb.2020.11.001,,,, +3149,HMGCR,,10.1016/j.apsb.2020.11.001,120,76,Degradation of HMGCR in HepG2 cells after 16 h treatment, +3150,BRD4,,10.1021/acschembio.1c00376,5,97,Degradation of BRD4 in HEK293T cells after 3 h treatment, +3151,CDK6,,10.1021/acsmedchemlett.1c00368,,,, +3151,CDK4,,10.1021/acsmedchemlett.1c00368,,,, +3152,CDK4,,10.1021/acsmedchemlett.1c00368,,,, +3152,CDK6,,10.1021/acsmedchemlett.1c00368,,,, +3153,CDK4,,10.1021/acsmedchemlett.1c00368,,,, +3153,CDK6,,10.1021/acsmedchemlett.1c00368,,,, +3154,AR,,10.1002/ardp.202100467,,,, +3155,AR,,10.1002/ardp.202100467,,,, +3156,AR,,10.1002/ardp.202100467,,,, +3157,AR,,10.1002/ardp.202100467,,,, +3158,AR,,10.1002/ardp.202100467,,,, +3159,AR,,10.1002/ardp.202100467,,,, +3160,AR,,10.1002/ardp.202100467,,,, +3161,AR,,10.1002/ardp.202100467,,,, +3162,AR,,10.1002/ardp.202100467,,,, +3163,AR,,10.1002/ardp.202100467,,,, +3164,AR,,10.1002/ardp.202100467,,,, +3165,AR,,10.1002/ardp.202100467,,,, +3166,AR,,10.1002/ardp.202100467,,,, +3167,AR,,10.1002/ardp.202100467,,,, +3168,AR,,10.1002/ardp.202100467,,,, +3169,AR,,10.1002/ardp.202100467,,,, +3170,AR,,10.1002/ardp.202100467,,,, +3171,AR,,10.1002/ardp.202100467,75/77,>75/>85,Degradation of AR in A549/LNCaP cells after 24 h treatment, +3172,AR,,10.1002/ardp.202100467,,,, +3173,SF3B1 K400E,,10.1016/j.chembiol.2021.04.018,,,, +3173,SF3B1,,10.1016/j.chembiol.2021.04.018,244,,Degradation of SF3B1 in K562 cells after 24 h treatment, +3174,BTK C481G,,10.1038/s41375-019-0440-x,26,,Degradation of BTK C481G in HeLa cells after 96 h treatment, +3174,BTK C481W,,10.1038/s41375-019-0440-x,41,,Degradation of BTK C481W in HeLa cells after 96 h treatment, +3174,BTK C481A,,10.1038/s41375-019-0440-x,15,,Degradation of BTK C481A in HeLa cells after 96 h treatment, +3174,BTK,,10.1038/s41375-019-0440-x,18,,Degradation of BTK in HeLa cells after 96 h treatment, +3174,BTK C481S,,10.1038/s41375-019-0440-x,29,,Degradation of BTK C481S in HBL-1 cells after 36 h treatment, +3174,BTK C481T,,10.1038/s41375-019-0440-x,38,,Degradation of BTK C481T in HeLa cells after 96 h treatment, +3175,BTK,,10.1038/s41422-021-00533-6,,,, +3176,BTK,,10.1038/s41422-021-00533-6,,,, +3177,BTK,,10.1038/s41422-021-00533-6,,,, +3178,BTK,,10.1038/s41422-021-00533-6,,,, +3179,BTK,,10.1038/s41422-021-00533-6,,,, +3180,BTK,,10.1038/s41422-021-00533-6,,,, +3181,BTK,,10.1038/s41422-021-00533-6,37,,Degradation of BTK in DOHH2 cells after 24 h treatment, +3182,BTK,,10.1038/s41422-021-00533-6,,,, +3183,BTK,,10.1038/s41422-021-00533-6,,,, +3184,BTK,,10.1038/s41422-021-00533-6,,,, +3185,BTK,,10.1038/s41422-021-00533-6,,,, +3186,BTK,,10.1038/s41422-021-00533-6,,,, +3187,BTK,,10.1038/s41422-021-00533-6,,,, +3188,BTK,,10.1038/s41422-021-00533-6,,,, +3189,EGFR e19d,,10.1039/d1cc05715d,,,, +3190,HDAC8,,10.1039/d2cc00272h,,,, +3191,HDAC8,,10.1039/d2cc00272h,,,, +3192,HDAC8,,10.1039/d2cc00272h,702,,Degradation of HDAC8 in Jurkat cells after 24 h treatment, +3193,HDAC8,,10.1039/d2cc00272h,,,, +3194,Tau,,10.3389/fncel.2022.801179,,,, +3195,Tau,,10.3389/fncel.2022.801179,,,, +3196,Tau,,10.3389/fncel.2022.801179,,,, +3197,Tau,,10.3389/fncel.2022.801179,,,, +3198,Tau,,10.3389/fncel.2022.801179,,,, +3199,Tau,,10.3389/fncel.2022.801179,,,, +3200,Tau,,10.3389/fncel.2022.801179,,,, +3201,Tau,,10.3389/fncel.2022.801179,,,, +3202,Tau,,10.3389/fncel.2022.801179,,,, +3203,Tau,,10.3389/fncel.2022.801179,,,, +3204,Tau,,10.3389/fncel.2022.801179,,,, +3205,Tau,,10.3389/fncel.2022.801179,,,, +3206,LXRB,,10.3389/fchem.2021.674967,,,, +3206,LXRA,,10.3389/fchem.2021.674967,,,, +3207,LXRB,,10.3389/fchem.2021.674967,,,, +3207,LXRA,,10.3389/fchem.2021.674967,,,, +3208,LXRB,,10.3389/fchem.2021.674967,,,, +3208,LXRA,,10.3389/fchem.2021.674967,,,, +3209,LXRA,,10.3389/fchem.2021.674967,,,, +3209,LXRB,,10.3389/fchem.2021.674967,,,, +3210,LXRB,,10.3389/fchem.2021.674967,,,, +3210,LXRA,,10.3389/fchem.2021.674967,,,, +3211,LXRA,,10.3389/fchem.2021.674967,,,, +3211,LXRB,,10.3389/fchem.2021.674967,,,, +3212,LXRB,,10.3389/fchem.2021.674967,,,, +3212,LXRA,,10.3389/fchem.2021.674967,,,, +3213,BCL2,,10.1038/s41467-021-27210-x,,47,, +3213,BCL-xL,,10.1038/s41467-021-27210-x,316.2,56,Degradation of BCL-xL in 293T cells after 16 h treatment, +3214,BCL-xL,,10.1038/s41467-021-27210-x,39.9,91,Degradation of BCL-xL in 293T cells after 16 h treatment, +3214,BCL2,,10.1038/s41467-021-27210-x,,47,, +3215,BCL-xL,,10.1038/s41467-021-27210-x,12.8,85,Degradation of BCL-xL in 293T cells after 16 h treatment, +3215,BCL2,,10.1038/s41467-021-27210-x,179.9,79,Degradation of BCL2 in 293T cells after 16 h treatment, +3216,BCL2,,10.1038/s41467-021-27210-x,54,94,Degradation of BCL2 in 293T cells after 16 h treatment, +3216,BCL-xL,,10.1038/s41467-021-27210-x,12.9,94,Degradation of BCL-xL in 293T cells after 16 h treatment, +3217,BCL2,,10.1038/s41467-021-27210-x,316.2,79,Degradation of BCL2 in 293T cells after 16 h treatment, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,, +3217,BCL-xL,,10.1038/s41467-021-27210-x,12.8,96,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL-xL,,10.1038/s41467-021-27210-x,12.1,81,Degradation of BCL-xL in 293T cells after 16 h treatment, +3218,BCL2,,10.1038/s41467-021-27210-x,354.8,69,Degradation of BCL2 in 293T cells after 16 h treatment, +3219,BCL2,,10.1038/s41467-021-27210-x,,38,, +3219,BCL-xL,,10.1038/s41467-021-27210-x,,38,, +3220,BCL-xL,,10.1038/s41467-021-27210-x,,,, +3220,BCL2,,10.1038/s41467-021-27210-x,,,, +3221,BCL2,,10.1038/s41467-021-27210-x,48,,Degradation of BCL2 in 293T cells after 16 h treatment, +3221,BCL-xL,,10.1038/s41467-021-27210-x,6,,Degradation of BCL-xL in 293T cells after 16 h treatment, +3222,HDAC1,,10.3390/molecules26237241,,,, +3222,HDAC6,,10.3390/molecules26237241,,,, +3222,HDAC3,,10.3390/molecules26237241,,,, +3223,HDAC1,,10.3390/molecules26237241,,,, +3223,HDAC6,,10.3390/molecules26237241,,,, +3223,HDAC3,,10.3390/molecules26237241,,,, +3224,HDAC1,,10.3390/molecules26237241,,,, +3224,HDAC6,,10.3390/molecules26237241,,,, +3224,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC6,,10.3390/molecules26237241,,,, +3225,HDAC3,,10.3390/molecules26237241,,,, +3225,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC1,,10.3390/molecules26237241,,,, +3226,HDAC3,,10.3390/molecules26237241,,,, +3226,HDAC6,,10.3390/molecules26237241,,,, +3227,HDAC1,,10.3390/molecules26237241,,,, +3227,HDAC3,,10.3390/molecules26237241,,,, +3227,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC6,,10.3390/molecules26237241,,,, +3228,HDAC1,,10.3390/molecules26237241,,,, +3228,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC3,,10.3390/molecules26237241,,,, +3229,HDAC1,,10.3390/molecules26237241,,,, +3229,HDAC6,,10.3390/molecules26237241,,,, +3230,HDAC3,,10.3390/molecules26237241,,,, +3230,HDAC1,,10.3390/molecules26237241,,,, +3230,HDAC6,,10.3390/molecules26237241,,,, +3231,HDAC3,,10.3390/molecules26237241,,,, +3231,HDAC1,,10.3390/molecules26237241,,,, +3231,HDAC6,,10.3390/molecules26237241,,,, +3232,HDAC3,,10.3390/molecules26237241,,,, +3232,HDAC1,,10.3390/molecules26237241,,,, +3232,HDAC6,,10.3390/molecules26237241,,,, +3233,HDAC3,,10.3390/molecules26237241,,,, +3233,HDAC1,,10.3390/molecules26237241,,,, +3233,HDAC6,,10.3390/molecules26237241,,,, +3234,HDAC3,,10.3390/molecules26237241,,,, +3234,HDAC1,,10.3390/molecules26237241,,,, +3234,HDAC6,,10.3390/molecules26237241,,,, +3235,HSF1,,10.3390/molecules27051655,,,, +3236,HSF1,,10.3390/molecules27051655,,,,