index	prediction
0	BACKGROUND
1	BACKGROUND
2	OBJECTIVE
3	METHODS
4	RESULTS
5	METHODS
6	METHODS
7	RESULTS
8	RESULTS
9	RESULTS
10	CONCLUSIONS
11	OBJECTIVE
12	METHODS
13	METHODS
14	RESULTS
15	RESULTS
16	RESULTS
17	CONCLUSIONS
18	OBJECTIVE
19	METHODS
20	RESULTS
21	RESULTS
22	RESULTS
23	RESULTS
24	RESULTS
25	METHODS
26	RESULTS
27	RESULTS
28	RESULTS
29	CONCLUSIONS
30	CONCLUSIONS
31	BACKGROUND
32	BACKGROUND
33	METHODS
34	METHODS
35	METHODS
36	RESULTS
37	RESULTS
38	RESULTS
39	RESULTS
40	RESULTS
41	CONCLUSIONS
42	CONCLUSIONS
43	BACKGROUND
44	OBJECTIVE
45	METHODS
46	METHODS
47	METHODS
48	METHODS
49	RESULTS
50	RESULTS
51	CONCLUSIONS
52	METHODS
53	CONCLUSIONS
54	OBJECTIVE
55	METHODS
56	METHODS
57	METHODS
58	METHODS
59	METHODS
60	METHODS
61	RESULTS
62	RESULTS
63	RESULTS
64	RESULTS
65	RESULTS
66	RESULTS
67	CONCLUSIONS
68	OBJECTIVE
69	METHODS
70	METHODS
71	METHODS
72	RESULTS
73	RESULTS
74	RESULTS
75	CONCLUSIONS
76	BACKGROUND
77	OBJECTIVE
78	METHODS
79	METHODS
80	METHODS
81	METHODS
82	RESULTS
83	RESULTS
84	RESULTS
85	RESULTS
86	RESULTS
87	CONCLUSIONS
88	BACKGROUND
89	BACKGROUND
90	BACKGROUND
91	BACKGROUND
92	METHODS
93	METHODS
94	CONCLUSIONS
95	CONCLUSIONS
96	BACKGROUND
97	OBJECTIVE
98	OBJECTIVE
99	BACKGROUND
100	METHODS
101	METHODS
102	METHODS
103	METHODS
104	METHODS
105	RESULTS
106	RESULTS
107	RESULTS
108	RESULTS
109	CONCLUSIONS
110	CONCLUSIONS
111	BACKGROUND
112	BACKGROUND
113	METHODS
114	METHODS
115	METHODS
116	METHODS
117	RESULTS
118	RESULTS
119	RESULTS
120	RESULTS
121	CONCLUSIONS
122	BACKGROUND
123	BACKGROUND
124	BACKGROUND
125	BACKGROUND
126	BACKGROUND
127	METHODS
128	METHODS
129	BACKGROUND
130	BACKGROUND
131	BACKGROUND
132	BACKGROUND
133	BACKGROUND
134	METHODS
135	METHODS
136	METHODS
137	METHODS
138	METHODS
139	RESULTS
140	RESULTS
141	RESULTS
142	CONCLUSIONS
143	CONCLUSIONS
144	CONCLUSIONS
145	BACKGROUND
146	OBJECTIVE
147	METHODS
148	METHODS
149	RESULTS
150	RESULTS
151	RESULTS
152	RESULTS
153	RESULTS
154	CONCLUSIONS
155	CONCLUSIONS
156	CONCLUSIONS
157	OBJECTIVE
158	METHODS
159	METHODS
160	METHODS
161	METHODS
162	METHODS
163	METHODS
164	METHODS
165	RESULTS
166	RESULTS
167	RESULTS
168	RESULTS
169	RESULTS
170	RESULTS
171	CONCLUSIONS
172	OBJECTIVE
173	METHODS
174	METHODS
175	METHODS
176	METHODS
177	METHODS
178	METHODS
179	METHODS
180	METHODS
181	RESULTS
182	RESULTS
183	CONCLUSIONS
184	CONCLUSIONS
185	OBJECTIVE
186	METHODS
187	METHODS
188	METHODS
189	METHODS
190	RESULTS
191	RESULTS
192	RESULTS
193	RESULTS
194	RESULTS
195	RESULTS
196	CONCLUSIONS
197	CONCLUSIONS
198	BACKGROUND
199	METHODS
200	METHODS
201	METHODS
202	METHODS
203	METHODS
204	RESULTS
205	RESULTS
206	CONCLUSIONS
207	BACKGROUND
208	OBJECTIVE
209	METHODS
210	METHODS
211	METHODS
212	RESULTS
213	RESULTS
214	RESULTS
215	RESULTS
216	RESULTS
217	RESULTS
218	CONCLUSIONS
219	OBJECTIVE
220	METHODS
221	METHODS
222	METHODS
223	RESULTS
224	RESULTS
225	RESULTS
226	RESULTS
227	RESULTS
228	RESULTS
229	RESULTS
230	CONCLUSIONS
231	RESULTS
232	RESULTS
233	CONCLUSIONS
234	BACKGROUND
235	CONCLUSIONS
236	OBJECTIVE
237	METHODS
238	RESULTS
239	RESULTS
240	RESULTS
241	RESULTS
242	RESULTS
243	BACKGROUND
244	CONCLUSIONS
245	CONCLUSIONS
246	BACKGROUND
247	BACKGROUND
248	OBJECTIVE
249	METHODS
250	METHODS
251	METHODS
252	METHODS
253	RESULTS
254	RESULTS
255	RESULTS
256	RESULTS
257	RESULTS
258	RESULTS
259	CONCLUSIONS
260	BACKGROUND
261	CONCLUSIONS
262	METHODS
263	METHODS
264	METHODS
265	METHODS
266	RESULTS
267	RESULTS
268	RESULTS
269	OBJECTIVE
270	OBJECTIVE
271	METHODS
272	METHODS
273	METHODS
274	METHODS
275	METHODS
276	METHODS
277	METHODS
278	METHODS
279	RESULTS
280	RESULTS
281	RESULTS
282	RESULTS
283	RESULTS
284	RESULTS
285	RESULTS
286	CONCLUSIONS
287	CONCLUSIONS
288	RESULTS
289	RESULTS
290	CONCLUSIONS
291	OBJECTIVE
292	OBJECTIVE
293	METHODS
294	METHODS
295	RESULTS
296	CONCLUSIONS
297	RESULTS
298	RESULTS
299	RESULTS
300	RESULTS
301	RESULTS
302	RESULTS
303	CONCLUSIONS
304	CONCLUSIONS
305	OBJECTIVE
306	BACKGROUND
307	BACKGROUND
308	METHODS
309	RESULTS
310	RESULTS
311	RESULTS
312	CONCLUSIONS
313	RESULTS
314	OBJECTIVE
315	METHODS
316	METHODS
317	METHODS
318	RESULTS
319	RESULTS
320	RESULTS
321	RESULTS
322	RESULTS
323	RESULTS
324	CONCLUSIONS
325	BACKGROUND
326	OBJECTIVE
327	BACKGROUND
328	BACKGROUND
329	METHODS
330	RESULTS
331	RESULTS
332	METHODS
333	RESULTS
334	RESULTS
335	CONCLUSIONS
336	CONCLUSIONS
337	CONCLUSIONS
338	OBJECTIVE
339	METHODS
340	METHODS
341	METHODS
342	METHODS
343	METHODS
344	METHODS
345	METHODS
346	RESULTS
347	RESULTS
348	RESULTS
349	CONCLUSIONS
350	CONCLUSIONS
351	BACKGROUND
352	OBJECTIVE
353	METHODS
354	METHODS
355	METHODS
356	RESULTS
357	RESULTS
358	CONCLUSIONS
359	OBJECTIVE
360	METHODS
361	METHODS
362	METHODS
363	METHODS
364	RESULTS
365	RESULTS
366	RESULTS
367	CONCLUSIONS
368	CONCLUSIONS
369	OBJECTIVE
370	METHODS
371	METHODS
372	METHODS
373	METHODS
374	RESULTS
375	RESULTS
376	RESULTS
377	RESULTS
378	CONCLUSIONS
379	RESULTS
380	BACKGROUND
381	BACKGROUND
382	BACKGROUND
383	METHODS
384	METHODS
385	METHODS
386	RESULTS
387	RESULTS
388	CONCLUSIONS
389	CONCLUSIONS
390	BACKGROUND
391	BACKGROUND
392	METHODS
393	METHODS
394	METHODS
395	METHODS
396	METHODS
397	RESULTS
398	RESULTS
399	RESULTS
400	RESULTS
401	RESULTS
402	RESULTS
403	CONCLUSIONS
404	BACKGROUND
405	CONCLUSIONS
406	OBJECTIVE
407	METHODS
408	METHODS
409	RESULTS
410	RESULTS
411	RESULTS
412	RESULTS
413	RESULTS
414	CONCLUSIONS
415	BACKGROUND
416	BACKGROUND
417	METHODS
418	METHODS
419	METHODS
420	METHODS
421	METHODS
422	METHODS
423	METHODS
424	METHODS
425	RESULTS
426	RESULTS
427	RESULTS
428	RESULTS
429	RESULTS
430	CONCLUSIONS
431	CONCLUSIONS
432	OBJECTIVE
433	METHODS
434	METHODS
435	METHODS
436	RESULTS
437	RESULTS
438	RESULTS
439	RESULTS
440	RESULTS
441	CONCLUSIONS
442	OBJECTIVE
443	OBJECTIVE
444	BACKGROUND
445	BACKGROUND
446	OBJECTIVE
447	RESULTS
448	RESULTS
449	RESULTS
450	METHODS
451	METHODS
452	METHODS
453	METHODS
454	METHODS
455	RESULTS
456	RESULTS
457	RESULTS
458	RESULTS
459	CONCLUSIONS
460	RESULTS
461	CONCLUSIONS
462	BACKGROUND
463	BACKGROUND
464	METHODS
465	METHODS
466	RESULTS
467	RESULTS
468	RESULTS
469	RESULTS
470	CONCLUSIONS
471	CONCLUSIONS
472	OBJECTIVE
473	BACKGROUND
474	METHODS
475	METHODS
476	METHODS
477	RESULTS
478	METHODS
479	RESULTS
480	RESULTS
481	RESULTS
482	RESULTS
483	RESULTS
484	RESULTS
485	CONCLUSIONS
486	OBJECTIVE
487	METHODS
488	METHODS
489	METHODS
490	METHODS
491	METHODS
492	METHODS
493	METHODS
494	RESULTS
495	RESULTS
496	RESULTS
497	CONCLUSIONS
498	OBJECTIVE
499	METHODS
500	METHODS
501	METHODS
502	METHODS
503	METHODS
504	METHODS
505	RESULTS
506	RESULTS
507	RESULTS
508	RESULTS
509	CONCLUSIONS
510	BACKGROUND
511	BACKGROUND
512	CONCLUSIONS
513	OBJECTIVE
514	METHODS
515	METHODS
516	METHODS
517	RESULTS
518	RESULTS
519	RESULTS
520	RESULTS
521	RESULTS
522	RESULTS
523	CONCLUSIONS
524	CONCLUSIONS
525	BACKGROUND
526	OBJECTIVE
527	OBJECTIVE
528	METHODS
529	METHODS
530	METHODS
531	METHODS
532	METHODS
533	METHODS
534	METHODS
535	RESULTS
536	RESULTS
537	CONCLUSIONS
538	OBJECTIVE
539	OBJECTIVE
540	RESULTS
541	RESULTS
542	RESULTS
543	RESULTS
544	RESULTS
545	OBJECTIVE
546	OBJECTIVE
547	METHODS
548	METHODS
549	RESULTS
550	RESULTS
551	RESULTS
552	CONCLUSIONS
553	OBJECTIVE
554	METHODS
555	METHODS
556	METHODS
557	METHODS
558	METHODS
559	METHODS
560	METHODS
561	METHODS
562	RESULTS
563	RESULTS
564	RESULTS
565	CONCLUSIONS
566	OBJECTIVE
567	METHODS
568	METHODS
569	METHODS
570	METHODS
571	RESULTS
572	RESULTS
573	RESULTS
574	RESULTS
575	CONCLUSIONS
576	RESULTS
577	RESULTS
578	RESULTS
579	CONCLUSIONS
580	BACKGROUND
581	BACKGROUND
582	METHODS
583	METHODS
584	RESULTS
585	RESULTS
586	RESULTS
587	RESULTS
588	RESULTS
589	RESULTS
590	RESULTS
591	RESULTS
592	RESULTS
593	CONCLUSIONS
594	CONCLUSIONS
595	BACKGROUND
596	BACKGROUND
597	BACKGROUND
598	BACKGROUND
599	CONCLUSIONS
600	CONCLUSIONS
601	METHODS
602	METHODS
603	METHODS
604	METHODS
605	METHODS
606	METHODS
607	BACKGROUND
608	BACKGROUND
609	BACKGROUND
610	OBJECTIVE
611	METHODS
612	METHODS
613	RESULTS
614	RESULTS
615	RESULTS
616	CONCLUSIONS
617	CONCLUSIONS
618	OBJECTIVE
619	METHODS
620	METHODS
621	METHODS
622	METHODS
623	METHODS
624	RESULTS
625	RESULTS
626	RESULTS
627	RESULTS
628	RESULTS
629	CONCLUSIONS
630	BACKGROUND
631	BACKGROUND
632	METHODS
633	METHODS
634	METHODS
635	CONCLUSIONS
636	METHODS
637	METHODS
638	METHODS
639	METHODS
640	CONCLUSIONS
641	BACKGROUND
642	BACKGROUND
643	OBJECTIVE
644	METHODS
645	METHODS
646	METHODS
647	RESULTS
648	RESULTS
649	CONCLUSIONS
650	CONCLUSIONS
651	CONCLUSIONS
652	OBJECTIVE
653	METHODS
654	METHODS
655	METHODS
656	RESULTS
657	RESULTS
658	RESULTS
659	RESULTS
660	CONCLUSIONS
661	RESULTS
662	RESULTS
663	OBJECTIVE
664	OBJECTIVE
665	METHODS
666	RESULTS
667	RESULTS
668	CONCLUSIONS
669	OBJECTIVE
670	METHODS
671	METHODS
672	METHODS
673	METHODS
674	METHODS
675	RESULTS
676	RESULTS
677	RESULTS
678	CONCLUSIONS
679	BACKGROUND
680	OBJECTIVE
681	METHODS
682	METHODS
683	METHODS
684	METHODS
685	METHODS
686	RESULTS
687	RESULTS
688	RESULTS
689	RESULTS
690	RESULTS
691	CONCLUSIONS
692	BACKGROUND
693	BACKGROUND
694	METHODS
695	METHODS
696	METHODS
697	RESULTS
698	RESULTS
699	RESULTS
700	RESULTS
701	CONCLUSIONS
702	RESULTS
703	OBJECTIVE
704	METHODS
705	RESULTS
706	RESULTS
707	RESULTS
708	CONCLUSIONS
709	CONCLUSIONS
710	OBJECTIVE
711	METHODS
712	METHODS
713	METHODS
714	METHODS
715	METHODS
716	METHODS
717	RESULTS
718	RESULTS
719	RESULTS
720	RESULTS
721	RESULTS
722	CONCLUSIONS
723	RESULTS
724	METHODS
725	OBJECTIVE
726	METHODS
727	METHODS
728	METHODS
729	METHODS
730	METHODS
731	METHODS
732	RESULTS
733	RESULTS
734	CONCLUSIONS
735	BACKGROUND
736	BACKGROUND
737	BACKGROUND
738	METHODS
739	METHODS
740	METHODS
741	CONCLUSIONS
742	RESULTS
743	CONCLUSIONS
744	CONCLUSIONS
745	CONCLUSIONS
746	BACKGROUND
747	OBJECTIVE
748	METHODS
749	METHODS
750	RESULTS
751	RESULTS
752	CONCLUSIONS
753	OBJECTIVE
754	METHODS
755	METHODS
756	METHODS
757	METHODS
758	METHODS
759	CONCLUSIONS
760	RESULTS
761	BACKGROUND
762	METHODS
763	METHODS
764	METHODS
765	RESULTS
766	RESULTS
767	RESULTS
768	CONCLUSIONS
769	BACKGROUND
770	BACKGROUND
771	BACKGROUND
772	BACKGROUND
773	OBJECTIVE
774	METHODS
775	METHODS
776	METHODS
777	METHODS
778	METHODS
779	RESULTS
780	RESULTS
781	RESULTS
782	CONCLUSIONS
783	CONCLUSIONS
784	CONCLUSIONS
785	CONCLUSIONS
786	BACKGROUND
787	BACKGROUND
788	METHODS
789	METHODS
790	METHODS
791	METHODS
792	METHODS
793	METHODS
794	METHODS
795	RESULTS
796	RESULTS
797	RESULTS
798	RESULTS
799	CONCLUSIONS
800	CONCLUSIONS
801	OBJECTIVE
802	METHODS
803	RESULTS
804	RESULTS
805	RESULTS
806	RESULTS
807	RESULTS
808	RESULTS
809	CONCLUSIONS
810	OBJECTIVE
811	METHODS
812	METHODS
813	METHODS
814	METHODS
815	METHODS
816	METHODS
817	METHODS
818	RESULTS
819	RESULTS
820	RESULTS
821	RESULTS
822	CONCLUSIONS
823	BACKGROUND
824	BACKGROUND
825	METHODS
826	METHODS
827	METHODS
828	METHODS
829	METHODS
830	RESULTS
831	RESULTS
832	RESULTS
833	RESULTS
834	CONCLUSIONS
835	CONCLUSIONS
836	BACKGROUND
837	OBJECTIVE
838	OBJECTIVE
839	METHODS
840	METHODS
841	METHODS
842	METHODS
843	RESULTS
844	RESULTS
845	RESULTS
846	RESULTS
847	RESULTS
848	RESULTS
849	CONCLUSIONS
850	CONCLUSIONS
851	BACKGROUND
852	BACKGROUND
853	BACKGROUND
854	METHODS
855	METHODS
856	METHODS
857	RESULTS
858	RESULTS
859	RESULTS
860	CONCLUSIONS
861	RESULTS
862	BACKGROUND
863	CONCLUSIONS
864	BACKGROUND
865	BACKGROUND
866	BACKGROUND
867	METHODS
868	METHODS
869	METHODS
870	RESULTS
871	RESULTS
872	RESULTS
873	RESULTS
874	RESULTS
875	CONCLUSIONS
876	CONCLUSIONS
877	BACKGROUND
878	CONCLUSIONS
879	OBJECTIVE
880	BACKGROUND
881	METHODS
882	METHODS
883	METHODS
884	RESULTS
885	RESULTS
886	RESULTS
887	RESULTS
888	RESULTS
889	CONCLUSIONS
890	CONCLUSIONS
891	CONCLUSIONS
892	OBJECTIVE
893	METHODS
894	METHODS
895	METHODS
896	METHODS
897	METHODS
898	RESULTS
899	RESULTS
900	RESULTS
901	RESULTS
902	RESULTS
903	RESULTS
904	CONCLUSIONS
905	BACKGROUND
906	METHODS
907	METHODS
908	METHODS
909	METHODS
910	RESULTS
911	RESULTS
912	RESULTS
913	RESULTS
914	CONCLUSIONS
915	RESULTS
916	BACKGROUND
917	BACKGROUND
918	BACKGROUND
919	METHODS
920	METHODS
921	METHODS
922	METHODS
923	RESULTS
924	RESULTS
925	RESULTS
926	CONCLUSIONS
927	CONCLUSIONS
928	BACKGROUND
929	OBJECTIVE
930	METHODS
931	METHODS
932	METHODS
933	METHODS
934	METHODS
935	METHODS
936	METHODS
937	METHODS
938	RESULTS
939	RESULTS
940	RESULTS
941	CONCLUSIONS
942	BACKGROUND
943	BACKGROUND
944	OBJECTIVE
945	METHODS
946	METHODS
947	METHODS
948	METHODS
949	RESULTS
950	RESULTS
951	RESULTS
952	RESULTS
953	RESULTS
954	RESULTS
955	CONCLUSIONS
956	CONCLUSIONS
957	OBJECTIVE
958	METHODS
959	METHODS
960	METHODS
961	RESULTS
962	RESULTS
963	RESULTS
964	RESULTS
965	RESULTS
966	CONCLUSIONS
967	BACKGROUND
968	OBJECTIVE
969	METHODS
970	METHODS
971	RESULTS
972	RESULTS
973	RESULTS
974	CONCLUSIONS
975	CONCLUSIONS
976	CONCLUSIONS
977	OBJECTIVE
978	METHODS
979	METHODS
980	METHODS
981	RESULTS
982	RESULTS
983	RESULTS
984	CONCLUSIONS
985	BACKGROUND
986	CONCLUSIONS
987	OBJECTIVE
988	RESULTS
989	RESULTS
990	RESULTS
991	RESULTS
992	CONCLUSIONS
993	CONCLUSIONS
994	BACKGROUND
995	BACKGROUND
996	BACKGROUND
997	METHODS
998	METHODS
999	METHODS
1000	RESULTS
1001	RESULTS
1002	RESULTS
1003	RESULTS
1004	CONCLUSIONS
1005	CONCLUSIONS
1006	BACKGROUND
1007	BACKGROUND
1008	BACKGROUND
1009	OBJECTIVE
1010	METHODS
1011	METHODS
1012	METHODS
1013	METHODS
1014	RESULTS
1015	RESULTS
1016	RESULTS
1017	RESULTS
1018	CONCLUSIONS
1019	CONCLUSIONS
1020	OBJECTIVE
1021	METHODS
1022	METHODS
1023	METHODS
1024	RESULTS
1025	RESULTS
1026	CONCLUSIONS
1027	OBJECTIVE
1028	METHODS
1029	METHODS
1030	RESULTS
1031	RESULTS
1032	METHODS
1033	METHODS
1034	METHODS
1035	METHODS
1036	RESULTS
1037	RESULTS
1038	CONCLUSIONS
1039	BACKGROUND
1040	BACKGROUND
1041	BACKGROUND
1042	BACKGROUND
1043	METHODS
1044	RESULTS
1045	RESULTS
1046	RESULTS
1047	RESULTS
1048	CONCLUSIONS
1049	CONCLUSIONS
1050	OBJECTIVE
1051	METHODS
1052	METHODS
1053	METHODS
1054	RESULTS
1055	RESULTS
1056	RESULTS
1057	CONCLUSIONS
1058	BACKGROUND
1059	OBJECTIVE
1060	METHODS
1061	METHODS
1062	METHODS
1063	METHODS
1064	METHODS
1065	METHODS
1066	METHODS
1067	METHODS
1068	METHODS
1069	METHODS
1070	RESULTS
1071	RESULTS
1072	RESULTS
1073	RESULTS
1074	CONCLUSIONS
1075	RESULTS
1076	BACKGROUND
1077	OBJECTIVE
1078	METHODS
1079	METHODS
1080	METHODS
1081	RESULTS
1082	RESULTS
1083	RESULTS
1084	RESULTS
1085	CONCLUSIONS
1086	BACKGROUND
1087	BACKGROUND
1088	BACKGROUND
1089	METHODS
1090	METHODS
1091	METHODS
1092	METHODS
1093	RESULTS
1094	RESULTS
1095	CONCLUSIONS
1096	RESULTS
1097	OBJECTIVE
1098	METHODS
1099	METHODS
1100	METHODS
1101	RESULTS
1102	RESULTS
1103	RESULTS
1104	RESULTS
1105	RESULTS
1106	CONCLUSIONS
1107	RESULTS
1108	CONCLUSIONS
1109	OBJECTIVE
1110	METHODS
1111	RESULTS
1112	RESULTS
1113	RESULTS
1114	CONCLUSIONS
1115	CONCLUSIONS
1116	CONCLUSIONS
1117	METHODS
1118	METHODS
1119	METHODS
1120	METHODS
1121	RESULTS
1122	RESULTS
1123	RESULTS
1124	RESULTS
1125	RESULTS
1126	RESULTS
1127	RESULTS
1128	CONCLUSIONS
1129	RESULTS
1130	OBJECTIVE
1131	METHODS
1132	RESULTS
1133	METHODS
1134	METHODS
1135	METHODS
1136	METHODS
1137	RESULTS
1138	RESULTS
1139	RESULTS
1140	RESULTS
1141	RESULTS
1142	RESULTS
1143	CONCLUSIONS
1144	OBJECTIVE
1145	METHODS
1146	METHODS
1147	METHODS
1148	METHODS
1149	METHODS
1150	METHODS
1151	RESULTS
1152	RESULTS
1153	RESULTS
1154	RESULTS
1155	RESULTS
1156	RESULTS
1157	CONCLUSIONS
1158	CONCLUSIONS
1159	CONCLUSIONS
1160	BACKGROUND
1161	OBJECTIVE
1162	METHODS
1163	METHODS
1164	METHODS
1165	RESULTS
1166	RESULTS
1167	RESULTS
1168	CONCLUSIONS
1169	CONCLUSIONS
1170	BACKGROUND
1171	OBJECTIVE
1172	METHODS
1173	RESULTS
1174	RESULTS
1175	RESULTS
1176	RESULTS
1177	RESULTS
1178	RESULTS
1179	CONCLUSIONS
1180	OBJECTIVE
1181	METHODS
1182	METHODS
1183	RESULTS
1184	RESULTS
1185	RESULTS
1186	RESULTS
1187	CONCLUSIONS
1188	CONCLUSIONS
1189	BACKGROUND
1190	BACKGROUND
1191	METHODS
1192	METHODS
1193	METHODS
1194	METHODS
1195	RESULTS
1196	RESULTS
1197	RESULTS
1198	RESULTS
1199	RESULTS
1200	RESULTS
1201	RESULTS
1202	RESULTS
1203	RESULTS
1204	RESULTS
1205	RESULTS
1206	CONCLUSIONS
1207	OBJECTIVE
1208	METHODS
1209	METHODS
1210	RESULTS
1211	RESULTS
1212	RESULTS
1213	RESULTS
1214	RESULTS
1215	RESULTS
1216	RESULTS
1217	RESULTS
1218	CONCLUSIONS
1219	BACKGROUND
1220	CONCLUSIONS
1221	METHODS
1222	METHODS
1223	BACKGROUND
1224	METHODS
1225	METHODS
1226	RESULTS
1227	RESULTS
1228	RESULTS
1229	RESULTS
1230	RESULTS
1231	RESULTS
1232	CONCLUSIONS
1233	RESULTS
1234	BACKGROUND
1235	BACKGROUND
1236	BACKGROUND
1237	METHODS
1238	METHODS
1239	METHODS
1240	METHODS
1241	METHODS
1242	RESULTS
1243	RESULTS
1244	RESULTS
1245	CONCLUSIONS
1246	BACKGROUND
1247	BACKGROUND
1248	METHODS
1249	METHODS
1250	METHODS
1251	RESULTS
1252	RESULTS
1253	RESULTS
1254	RESULTS
1255	RESULTS
1256	BACKGROUND
1257	OBJECTIVE
1258	OBJECTIVE
1259	METHODS
1260	METHODS
1261	METHODS
1262	METHODS
1263	METHODS
1264	RESULTS
1265	RESULTS
1266	RESULTS
1267	RESULTS
1268	RESULTS
1269	RESULTS
1270	BACKGROUND
1271	OBJECTIVE
1272	BACKGROUND
1273	OBJECTIVE
1274	METHODS
1275	METHODS
1276	METHODS
1277	RESULTS
1278	RESULTS
1279	RESULTS
1280	RESULTS
1281	RESULTS
1282	CONCLUSIONS
1283	CONCLUSIONS
1284	CONCLUSIONS
1285	BACKGROUND
1286	CONCLUSIONS
1287	OBJECTIVE
1288	METHODS
1289	METHODS
1290	RESULTS
1291	RESULTS
1292	RESULTS
1293	RESULTS
1294	CONCLUSIONS
1295	CONCLUSIONS
1296	CONCLUSIONS
1297	BACKGROUND
1298	BACKGROUND
1299	OBJECTIVE
1300	METHODS
1301	METHODS
1302	METHODS
1303	RESULTS
1304	RESULTS
1305	RESULTS
1306	RESULTS
1307	RESULTS
1308	CONCLUSIONS
1309	BACKGROUND
1310	OBJECTIVE
1311	BACKGROUND
1312	BACKGROUND
1313	METHODS
1314	METHODS
1315	RESULTS
1316	RESULTS
1317	RESULTS
1318	RESULTS
1319	RESULTS
1320	METHODS
1321	METHODS
1322	RESULTS
1323	BACKGROUND
1324	BACKGROUND
1325	BACKGROUND
1326	CONCLUSIONS
1327	BACKGROUND
1328	METHODS
1329	METHODS
1330	METHODS
1331	METHODS
1332	METHODS
1333	METHODS
1334	CONCLUSIONS
1335	CONCLUSIONS
1336	BACKGROUND
1337	OBJECTIVE
1338	METHODS
1339	METHODS
1340	METHODS
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1609	OBJECTIVE
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1827	OBJECTIVE
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1859	BACKGROUND
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1870	OBJECTIVE
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1882	METHODS
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1888	BACKGROUND
1889	OBJECTIVE
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1897	OBJECTIVE
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1899	METHODS
1900	METHODS
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1908	CONCLUSIONS
1909	OBJECTIVE
1910	METHODS
1911	METHODS
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1914	RESULTS
1915	RESULTS
1916	RESULTS
1917	CONCLUSIONS
1918	RESULTS
1919	RESULTS
1920	CONCLUSIONS
1921	BACKGROUND
1922	METHODS
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1928	CONCLUSIONS
1929	BACKGROUND
1930	BACKGROUND
1931	OBJECTIVE
1932	METHODS
1933	METHODS
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1939	CONCLUSIONS
1940	OBJECTIVE
1941	METHODS
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1948	CONCLUSIONS
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1950	OBJECTIVE
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1953	METHODS
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1959	OBJECTIVE
1960	CONCLUSIONS
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1963	BACKGROUND
1964	BACKGROUND
1965	METHODS
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1971	CONCLUSIONS
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1973	BACKGROUND
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1987	RESULTS
1988	CONCLUSIONS
1989	RESULTS
1990	BACKGROUND
1991	OBJECTIVE
1992	METHODS
1993	METHODS
1994	METHODS
1995	RESULTS
1996	RESULTS
1997	CONCLUSIONS
1998	CONCLUSIONS
1999	CONCLUSIONS
2000	OBJECTIVE
2001	METHODS
2002	METHODS
2003	METHODS
2004	METHODS
2005	METHODS
2006	RESULTS
2007	RESULTS
2008	RESULTS
2009	CONCLUSIONS
2010	BACKGROUND
2011	METHODS
2012	METHODS
2013	METHODS
2014	METHODS
2015	METHODS
2016	METHODS
2017	METHODS
2018	RESULTS
2019	RESULTS
2020	RESULTS
2021	CONCLUSIONS
2022	CONCLUSIONS
2023	BACKGROUND
2024	BACKGROUND
2025	METHODS
2026	METHODS
2027	RESULTS
2028	CONCLUSIONS
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2030	OBJECTIVE
2031	METHODS
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2039	CONCLUSIONS
2040	OBJECTIVE
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2095	CONCLUSIONS
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2099	METHODS
2100	METHODS
2101	RESULTS
2102	RESULTS
2103	RESULTS
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2105	RESULTS
2106	RESULTS
2107	CONCLUSIONS
2108	CONCLUSIONS
2109	RESULTS
2110	CONCLUSIONS
2111	CONCLUSIONS
2112	OBJECTIVE
2113	BACKGROUND
2114	CONCLUSIONS
2115	METHODS
2116	METHODS
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2119	RESULTS
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2123	BACKGROUND
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2129	METHODS
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2136	CONCLUSIONS
2137	OBJECTIVE
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2142	RESULTS
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2148	CONCLUSIONS
2149	METHODS
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2157	METHODS
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2159	RESULTS
2160	RESULTS
2161	RESULTS
2162	CONCLUSIONS
2163	CONCLUSIONS
2164	BACKGROUND
2165	METHODS
2166	METHODS
2167	METHODS
2168	RESULTS
2169	RESULTS
2170	BACKGROUND
2171	CONCLUSIONS
2172	CONCLUSIONS
2173	OBJECTIVE
2174	METHODS
2175	RESULTS
2176	METHODS
2177	RESULTS
2178	CONCLUSIONS
2179	RESULTS
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2182	CONCLUSIONS
2183	OBJECTIVE
2184	METHODS
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2190	CONCLUSIONS
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2192	RESULTS
2193	CONCLUSIONS
2194	OBJECTIVE
2195	METHODS
2196	METHODS
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2198	RESULTS
2199	RESULTS
2200	RESULTS
2201	CONCLUSIONS
2202	BACKGROUND
2203	BACKGROUND
2204	OBJECTIVE
2205	METHODS
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2209	RESULTS
2210	RESULTS
2211	CONCLUSIONS
2212	BACKGROUND
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2215	OBJECTIVE
2216	METHODS
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2224	CONCLUSIONS
2225	BACKGROUND
2226	OBJECTIVE
2227	METHODS
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2233	CONCLUSIONS
2234	BACKGROUND
2235	OBJECTIVE
2236	METHODS
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2239	METHODS
2240	RESULTS
2241	CONCLUSIONS
2242	OBJECTIVE
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2248	RESULTS
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2250	RESULTS
2251	RESULTS
2252	CONCLUSIONS
2253	BACKGROUND
2254	METHODS
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2260	METHODS
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2265	RESULTS
2266	RESULTS
2267	CONCLUSIONS
2268	BACKGROUND
2269	OBJECTIVE
2270	METHODS
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2284	OBJECTIVE
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2290	CONCLUSIONS
2291	OBJECTIVE
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2300	RESULTS
2301	RESULTS
2302	RESULTS
2303	CONCLUSIONS
2304	METHODS
2305	BACKGROUND
2306	OBJECTIVE
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2314	BACKGROUND
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2316	METHODS
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2321	RESULTS
2322	RESULTS
2323	RESULTS
2324	RESULTS
2325	CONCLUSIONS
2326	BACKGROUND
2327	OBJECTIVE
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2329	METHODS
2330	METHODS
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2333	RESULTS
2334	RESULTS
2335	RESULTS
2336	CONCLUSIONS
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2338	BACKGROUND
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2340	CONCLUSIONS
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2342	OBJECTIVE
2343	BACKGROUND
2344	METHODS
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2351	CONCLUSIONS
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2353	BACKGROUND
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2355	BACKGROUND
2356	OBJECTIVE
2357	METHODS
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2366	CONCLUSIONS
2367	BACKGROUND
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2369	METHODS
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2378	CONCLUSIONS
2379	BACKGROUND
2380	CONCLUSIONS
2381	OBJECTIVE
2382	METHODS
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2387	CONCLUSIONS
2388	BACKGROUND
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2390	METHODS
2391	RESULTS
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2395	RESULTS
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2397	CONCLUSIONS
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2399	CONCLUSIONS
2400	OBJECTIVE
2401	METHODS
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2412	RESULTS
2413	CONCLUSIONS
2414	BACKGROUND
2415	CONCLUSIONS
2416	OBJECTIVE
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2418	METHODS
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2422	RESULTS
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2425	CONCLUSIONS
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2427	BACKGROUND
2428	METHODS
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2432	RESULTS
2433	RESULTS
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2436	RESULTS
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2438	RESULTS
2439	RESULTS
2440	CONCLUSIONS
2441	BACKGROUND
2442	CONCLUSIONS
2443	METHODS
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2446	RESULTS
2447	RESULTS
2448	CONCLUSIONS
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2450	CONCLUSIONS
2451	OBJECTIVE
2452	METHODS
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2454	RESULTS
2455	RESULTS
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2459	METHODS
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2463	OBJECTIVE
2464	METHODS
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2470	CONCLUSIONS
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2480	OBJECTIVE
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2487	RESULTS
2488	RESULTS
2489	CONCLUSIONS
2490	OBJECTIVE
2491	METHODS
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2496	METHODS
2497	RESULTS
2498	RESULTS
2499	RESULTS
2500	RESULTS
2501	RESULTS
2502	RESULTS
2503	RESULTS
2504	CONCLUSIONS
2505	OBJECTIVE
2506	METHODS
2507	METHODS
2508	METHODS
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2510	RESULTS
2511	RESULTS
2512	RESULTS
2513	RESULTS
2514	RESULTS
2515	RESULTS
2516	RESULTS
2517	RESULTS
2518	RESULTS
2519	CONCLUSIONS
2520	BACKGROUND
2521	METHODS
2522	BACKGROUND
2523	RESULTS
2524	RESULTS
2525	BACKGROUND
2526	RESULTS
2527	RESULTS
2528	CONCLUSIONS
2529	CONCLUSIONS
2530	OBJECTIVE
2531	METHODS
2532	METHODS
2533	METHODS
2534	METHODS
2535	METHODS
2536	METHODS
2537	METHODS
2538	RESULTS
2539	RESULTS
2540	RESULTS
2541	RESULTS
2542	RESULTS
2543	RESULTS
2544	CONCLUSIONS
2545	RESULTS
2546	BACKGROUND
2547	BACKGROUND
2548	OBJECTIVE
2549	METHODS
2550	METHODS
2551	RESULTS
2552	RESULTS
2553	RESULTS
2554	RESULTS
2555	RESULTS
2556	CONCLUSIONS
2557	CONCLUSIONS
2558	BACKGROUND
2559	OBJECTIVE
2560	METHODS
2561	METHODS
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2999	OBJECTIVE
3000	METHODS
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3762	CONCLUSIONS
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3764	OBJECTIVE
3765	METHODS
3766	RESULTS
3767	RESULTS
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3770	CONCLUSIONS
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3772	OBJECTIVE
3773	METHODS
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3787	CONCLUSIONS
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3789	BACKGROUND
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3791	OBJECTIVE
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3806	OBJECTIVE
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3820	OBJECTIVE
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3831	OBJECTIVE
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3841	OBJECTIVE
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3855	BACKGROUND
3856	OBJECTIVE
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3873	BACKGROUND
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3896	OBJECTIVE
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3914	OBJECTIVE
3915	METHODS
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3923	CONCLUSIONS
3924	OBJECTIVE
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3926	METHODS
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3935	BACKGROUND
3936	METHODS
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3944	BACKGROUND
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3956	CONCLUSIONS
3957	OBJECTIVE
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3964	OBJECTIVE
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3975	BACKGROUND
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3988	OBJECTIVE
3989	BACKGROUND
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4000	CONCLUSIONS
4001	RESULTS
4002	OBJECTIVE
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4027	BACKGROUND
4028	OBJECTIVE
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4038	OBJECTIVE
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4050	BACKGROUND
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4057	BACKGROUND
4058	OBJECTIVE
4059	METHODS
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4076	BACKGROUND
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4101	OBJECTIVE
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4116	BACKGROUND
4117	OBJECTIVE
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4129	OBJECTIVE
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4156	OBJECTIVE
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4180	BACKGROUND
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4203	BACKGROUND
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4216	OBJECTIVE
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4224	OBJECTIVE
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4255	OBJECTIVE
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4279	OBJECTIVE
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4317	BACKGROUND
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4319	OBJECTIVE
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4331	OBJECTIVE
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4361	OBJECTIVE
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4404	OBJECTIVE
4405	BACKGROUND
4406	OBJECTIVE
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4415	OBJECTIVE
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4500	RESULTS
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4503	BACKGROUND
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4531	OBJECTIVE
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4533	METHODS
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4540	BACKGROUND
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4581	BACKGROUND
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4600	METHODS
4601	RESULTS
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4607	BACKGROUND
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4610	RESULTS
4611	RESULTS
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4613	CONCLUSIONS
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4615	OBJECTIVE
4616	METHODS
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4620	RESULTS
4621	RESULTS
4622	RESULTS
4623	RESULTS
4624	RESULTS
4625	RESULTS
4626	CONCLUSIONS
4627	BACKGROUND
4628	OBJECTIVE
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4630	METHODS
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4632	CONCLUSIONS
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4638	BACKGROUND
4639	BACKGROUND
4640	CONCLUSIONS
4641	OBJECTIVE
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4650	RESULTS
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4695	BACKGROUND
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4710	CONCLUSIONS
4711	BACKGROUND
4712	BACKGROUND
4713	OBJECTIVE
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4718	RESULTS
4719	CONCLUSIONS
4720	OBJECTIVE
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4722	METHODS
4723	METHODS
4724	METHODS
4725	CONCLUSIONS
4726	RESULTS
4727	RESULTS
4728	RESULTS
4729	RESULTS
4730	RESULTS
4731	RESULTS
4732	CONCLUSIONS
4733	BACKGROUND
4734	METHODS
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4736	METHODS
4737	RESULTS
4738	RESULTS
4739	RESULTS
4740	CONCLUSIONS
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4742	BACKGROUND
4743	BACKGROUND
4744	BACKGROUND
4745	METHODS
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4760	METHODS
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4794	RESULTS
4795	RESULTS
4796	CONCLUSIONS
4797	BACKGROUND
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4800	METHODS
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4805	RESULTS
4806	RESULTS
4807	CONCLUSIONS
4808	BACKGROUND
4809	OBJECTIVE
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4820	BACKGROUND
4821	METHODS
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4826	RESULTS
4827	RESULTS
4828	RESULTS
4829	CONCLUSIONS
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4832	OBJECTIVE
4833	METHODS
4834	METHODS
4835	METHODS
4836	METHODS
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4838	METHODS
4839	METHODS
4840	METHODS
4841	RESULTS
4842	RESULTS
4843	RESULTS
4844	RESULTS
4845	CONCLUSIONS
4846	RESULTS
4847	METHODS
4848	RESULTS
4849	RESULTS
4850	RESULTS
4851	RESULTS
4852	RESULTS
4853	CONCLUSIONS
4854	BACKGROUND
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4860	RESULTS
4861	RESULTS
4862	RESULTS
4863	RESULTS
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4865	CONCLUSIONS
4866	BACKGROUND
4867	OBJECTIVE
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4876	RESULTS
4877	RESULTS
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4879	CONCLUSIONS
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4881	CONCLUSIONS
4882	BACKGROUND
4883	BACKGROUND
4884	BACKGROUND
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4889	METHODS
4890	RESULTS
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4892	RESULTS
4893	RESULTS
4894	CONCLUSIONS
4895	BACKGROUND
4896	BACKGROUND
4897	CONCLUSIONS
4898	BACKGROUND
4899	RESULTS
4900	CONCLUSIONS
4901	BACKGROUND
4902	OBJECTIVE
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4909	RESULTS
4910	RESULTS
4911	CONCLUSIONS
4912	BACKGROUND
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4914	METHODS
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4920	CONCLUSIONS
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4922	BACKGROUND
4923	OBJECTIVE
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4925	METHODS
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4931	RESULTS
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4933	CONCLUSIONS
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4935	BACKGROUND
4936	OBJECTIVE
4937	METHODS
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4942	RESULTS
4943	RESULTS
4944	RESULTS
4945	RESULTS
4946	RESULTS
4947	RESULTS
4948	CONCLUSIONS
4949	RESULTS
4950	CONCLUSIONS
4951	CONCLUSIONS
4952	OBJECTIVE
4953	METHODS
4954	METHODS
4955	METHODS
4956	METHODS
4957	RESULTS
4958	RESULTS
4959	RESULTS
4960	RESULTS
4961	RESULTS
4962	CONCLUSIONS
4963	CONCLUSIONS
4964	CONCLUSIONS
4965	BACKGROUND
4966	OBJECTIVE
4967	METHODS
4968	METHODS
4969	METHODS
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4991	BACKGROUND
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5043	BACKGROUND
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5119	OBJECTIVE
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5282	OBJECTIVE
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5344	OBJECTIVE
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5364	OBJECTIVE
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5410	BACKGROUND
5411	OBJECTIVE
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5430	OBJECTIVE
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5612	BACKGROUND
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5740	OBJECTIVE
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5817	CONCLUSIONS
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5820	OBJECTIVE
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5825	BACKGROUND
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5827	OBJECTIVE
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5836	OBJECTIVE
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5848	CONCLUSIONS
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5900	CONCLUSIONS
5901	BACKGROUND
5902	OBJECTIVE
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5913	BACKGROUND
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5926	OBJECTIVE
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5936	RESULTS
5937	RESULTS
5938	CONCLUSIONS
5939	BACKGROUND
5940	METHODS
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5944	RESULTS
5945	RESULTS
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5948	BACKGROUND
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5990	RESULTS
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5995	BACKGROUND
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5997	OBJECTIVE
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6035	CONCLUSIONS
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6037	BACKGROUND
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6039	OBJECTIVE
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6072	RESULTS
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6098	BACKGROUND
6099	CONCLUSIONS
6100	OBJECTIVE
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6110	RESULTS
6111	RESULTS
6112	RESULTS
6113	RESULTS
6114	RESULTS
6115	RESULTS
6116	RESULTS
6117	CONCLUSIONS
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6119	CONCLUSIONS
6120	OBJECTIVE
6121	BACKGROUND
6122	OBJECTIVE
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6127	RESULTS
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6132	CONCLUSIONS
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6134	BACKGROUND
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6136	METHODS
6137	RESULTS
6138	RESULTS
6139	CONCLUSIONS
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6141	OBJECTIVE
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6144	RESULTS
6145	CONCLUSIONS
6146	BACKGROUND
6147	BACKGROUND
6148	OBJECTIVE
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6151	RESULTS
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6154	CONCLUSIONS
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6157	METHODS
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6160	METHODS
6161	RESULTS
6162	RESULTS
6163	RESULTS
6164	RESULTS
6165	CONCLUSIONS
6166	CONCLUSIONS
6167	BACKGROUND
6168	BACKGROUND
6169	BACKGROUND
6170	METHODS
6171	METHODS
6172	RESULTS
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7340	METHODS
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8214	OBJECTIVE
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8299	RESULTS
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8310	RESULTS
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8313	CONCLUSIONS
8314	OBJECTIVE
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8321	RESULTS
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8327	BACKGROUND
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8380	BACKGROUND
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8382	OBJECTIVE
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8400	CONCLUSIONS
8401	BACKGROUND
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8413	OBJECTIVE
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8421	OBJECTIVE
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8426	RESULTS
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8429	CONCLUSIONS
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8431	OBJECTIVE
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8437	RESULTS
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8441	RESULTS
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8445	BACKGROUND
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8460	BACKGROUND
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8462	OBJECTIVE
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8472	BACKGROUND
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8495	OBJECTIVE
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8507	RESULTS
8508	CONCLUSIONS
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8510	CONCLUSIONS
8511	OBJECTIVE
8512	METHODS
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8514	RESULTS
8515	RESULTS
8516	RESULTS
8517	CONCLUSIONS
8518	BACKGROUND
8519	CONCLUSIONS
8520	BACKGROUND
8521	METHODS
8522	RESULTS
8523	RESULTS
8524	RESULTS
8525	RESULTS
8526	RESULTS
8527	RESULTS
8528	RESULTS
8529	CONCLUSIONS
8530	OBJECTIVE
8531	METHODS
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8533	METHODS
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8535	METHODS
8536	METHODS
8537	CONCLUSIONS
8538	CONCLUSIONS
8539	CONCLUSIONS
8540	CONCLUSIONS
8541	OBJECTIVE
8542	METHODS
8543	METHODS
8544	METHODS
8545	RESULTS
8546	CONCLUSIONS
8547	RESULTS
8548	RESULTS
8549	CONCLUSIONS
8550	BACKGROUND
8551	METHODS
8552	METHODS
8553	RESULTS
8554	RESULTS
8555	RESULTS
8556	RESULTS
8557	CONCLUSIONS
8558	OBJECTIVE
8559	BACKGROUND
8560	METHODS
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8564	METHODS
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8566	RESULTS
8567	RESULTS
8568	RESULTS
8569	CONCLUSIONS
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8571	BACKGROUND
8572	OBJECTIVE
8573	METHODS
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8575	METHODS
8576	METHODS
8577	METHODS
8578	RESULTS
8579	RESULTS
8580	RESULTS
8581	RESULTS
8582	CONCLUSIONS
8583	CONCLUSIONS
8584	OBJECTIVE
8585	BACKGROUND
8586	RESULTS
8587	METHODS
8588	RESULTS
8589	RESULTS
8590	CONCLUSIONS
8591	CONCLUSIONS
8592	BACKGROUND
8593	BACKGROUND
8594	METHODS
8595	METHODS
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8597	METHODS
8598	RESULTS
8599	RESULTS
8600	RESULTS
8601	CONCLUSIONS
8602	BACKGROUND
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8609	CONCLUSIONS
8610	OBJECTIVE
8611	METHODS
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8615	METHODS
8616	RESULTS
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8619	RESULTS
8620	RESULTS
8621	CONCLUSIONS
8622	CONCLUSIONS
8623	CONCLUSIONS
8624	OBJECTIVE
8625	METHODS
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8627	METHODS
8628	RESULTS
8629	CONCLUSIONS
8630	CONCLUSIONS
8631	OBJECTIVE
8632	METHODS
8633	METHODS
8634	METHODS
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8636	METHODS
8637	METHODS
8638	CONCLUSIONS
8639	METHODS
8640	METHODS
8641	METHODS
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8645	RESULTS
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8647	BACKGROUND
8648	BACKGROUND
8649	OBJECTIVE
8650	METHODS
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8660	METHODS
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8664	OBJECTIVE
8665	METHODS
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8669	RESULTS
8670	CONCLUSIONS
8671	CONCLUSIONS
8672	BACKGROUND
8673	OBJECTIVE
8674	BACKGROUND
8675	OBJECTIVE
8676	METHODS
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8680	RESULTS
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8685	RESULTS
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8688	CONCLUSIONS
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8690	BACKGROUND
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8692	METHODS
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8698	RESULTS
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8700	RESULTS
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8702	CONCLUSIONS
8703	BACKGROUND
8704	BACKGROUND
8705	BACKGROUND
8706	OBJECTIVE
8707	METHODS
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8715	RESULTS
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8718	CONCLUSIONS
8719	CONCLUSIONS
8720	BACKGROUND
8721	BACKGROUND
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8723	METHODS
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8735	RESULTS
8736	CONCLUSIONS
8737	CONCLUSIONS
8738	BACKGROUND
8739	BACKGROUND
8740	BACKGROUND
8741	METHODS
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8746	RESULTS
8747	RESULTS
8748	CONCLUSIONS
8749	BACKGROUND
8750	OBJECTIVE
8751	METHODS
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8757	RESULTS
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8759	CONCLUSIONS
8760	OBJECTIVE
8761	METHODS
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8766	CONCLUSIONS
8767	RESULTS
8768	CONCLUSIONS
8769	OBJECTIVE
8770	METHODS
8771	METHODS
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8773	RESULTS
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8775	RESULTS
8776	CONCLUSIONS
8777	CONCLUSIONS
8778	BACKGROUND
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8780	METHODS
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8784	RESULTS
8785	CONCLUSIONS
8786	OBJECTIVE
8787	METHODS
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8794	RESULTS
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8796	CONCLUSIONS
8797	CONCLUSIONS
8798	BACKGROUND
8799	OBJECTIVE
8800	METHODS
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8806	OBJECTIVE
8807	METHODS
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8809	RESULTS
8810	RESULTS
8811	RESULTS
8812	RESULTS
8813	RESULTS
8814	CONCLUSIONS
8815	BACKGROUND
8816	OBJECTIVE
8817	OBJECTIVE
8818	METHODS
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8820	METHODS
8821	METHODS
8822	METHODS
8823	RESULTS
8824	RESULTS
8825	RESULTS
8826	RESULTS
8827	CONCLUSIONS
8828	CONCLUSIONS
8829	BACKGROUND
8830	BACKGROUND
8831	BACKGROUND
8832	OBJECTIVE
8833	METHODS
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8838	CONCLUSIONS
8839	BACKGROUND
8840	BACKGROUND
8841	BACKGROUND
8842	OBJECTIVE
8843	METHODS
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8847	RESULTS
8848	RESULTS
8849	CONCLUSIONS
8850	OBJECTIVE
8851	BACKGROUND
8852	METHODS
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8854	RESULTS
8855	RESULTS
8856	RESULTS
8857	RESULTS
8858	CONCLUSIONS
8859	CONCLUSIONS
8860	BACKGROUND
8861	CONCLUSIONS
8862	BACKGROUND
8863	BACKGROUND
8864	BACKGROUND
8865	METHODS
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8874	RESULTS
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8876	CONCLUSIONS
8877	METHODS
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8879	BACKGROUND
8880	BACKGROUND
8881	METHODS
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8887	CONCLUSIONS
8888	CONCLUSIONS
8889	BACKGROUND
8890	BACKGROUND
8891	BACKGROUND
8892	OBJECTIVE
8893	METHODS
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8900	CONCLUSIONS
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8902	OBJECTIVE
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8906	RESULTS
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8910	CONCLUSIONS
8911	BACKGROUND
8912	RESULTS
8913	METHODS
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8915	RESULTS
8916	RESULTS
8917	RESULTS
8918	CONCLUSIONS
8919	BACKGROUND
8920	OBJECTIVE
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8922	RESULTS
8923	CONCLUSIONS
8924	OBJECTIVE
8925	METHODS
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8927	METHODS
8928	METHODS
8929	RESULTS
8930	RESULTS
8931	RESULTS
8932	RESULTS
8933	CONCLUSIONS
8934	BACKGROUND
8935	BACKGROUND
8936	CONCLUSIONS
8937	BACKGROUND
8938	METHODS
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8941	RESULTS
8942	RESULTS
8943	CONCLUSIONS
8944	BACKGROUND
8945	OBJECTIVE
8946	METHODS
8947	METHODS
8948	METHODS
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8951	RESULTS
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8954	CONCLUSIONS
8955	BACKGROUND
8956	OBJECTIVE
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8964	RESULTS
8965	CONCLUSIONS
8966	RESULTS
8967	RESULTS
8968	OBJECTIVE
8969	METHODS
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8979	CONCLUSIONS
8980	OBJECTIVE
8981	METHODS
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8986	METHODS
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8988	RESULTS
8989	RESULTS
8990	CONCLUSIONS
8991	BACKGROUND
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8994	METHODS
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8999	OBJECTIVE
9000	METHODS
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9007	CONCLUSIONS
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9009	CONCLUSIONS
9010	BACKGROUND
9011	BACKGROUND
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9015	METHODS
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9020	RESULTS
9021	RESULTS
9022	RESULTS
9023	CONCLUSIONS
9024	OBJECTIVE
9025	METHODS
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9027	METHODS
9028	METHODS
9029	METHODS
9030	METHODS
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9033	RESULTS
9034	RESULTS
9035	RESULTS
9036	RESULTS
9037	RESULTS
9038	RESULTS
9039	RESULTS
9040	OBJECTIVE
9041	METHODS
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9044	RESULTS
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9046	CONCLUSIONS
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9048	OBJECTIVE
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9059	BACKGROUND
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9061	METHODS
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9069	BACKGROUND
9070	OBJECTIVE
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9082	OBJECTIVE
9083	METHODS
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9091	RESULTS
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9093	CONCLUSIONS
9094	CONCLUSIONS
9095	BACKGROUND
9096	OBJECTIVE
9097	METHODS
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9101	RESULTS
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9106	CONCLUSIONS
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9109	METHODS
9110	METHODS
9111	METHODS
9112	METHODS
9113	METHODS
9114	OBJECTIVE
9115	RESULTS
9116	RESULTS
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9119	CONCLUSIONS
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9121	BACKGROUND
9122	OBJECTIVE
9123	METHODS
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9130	OBJECTIVE
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9141	CONCLUSIONS
9142	BACKGROUND
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9144	METHODS
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9151	RESULTS
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9153	RESULTS
9154	RESULTS
9155	RESULTS
9156	RESULTS
9157	CONCLUSIONS
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9159	OBJECTIVE
9160	METHODS
9161	RESULTS
9162	RESULTS
9163	RESULTS
9164	RESULTS
9165	RESULTS
9166	RESULTS
9167	CONCLUSIONS
9168	METHODS
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9171	METHODS
9172	RESULTS
9173	RESULTS
9174	RESULTS
9175	RESULTS
9176	RESULTS
9177	RESULTS
9178	RESULTS
9179	CONCLUSIONS
9180	BACKGROUND
9181	METHODS
9182	METHODS
9183	METHODS
9184	RESULTS
9185	RESULTS
9186	RESULTS
9187	RESULTS
9188	RESULTS
9189	RESULTS
9190	RESULTS
9191	RESULTS
9192	BACKGROUND
9193	OBJECTIVE
9194	BACKGROUND
9195	BACKGROUND
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9202	CONCLUSIONS
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9204	OBJECTIVE
9205	METHODS
9206	METHODS
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9209	METHODS
9210	METHODS
9211	RESULTS
9212	RESULTS
9213	RESULTS
9214	RESULTS
9215	CONCLUSIONS
9216	BACKGROUND
9217	OBJECTIVE
9218	METHODS
9219	METHODS
9220	METHODS
9221	METHODS
9222	RESULTS
9223	RESULTS
9224	RESULTS
9225	RESULTS
9226	RESULTS
9227	RESULTS
9228	CONCLUSIONS
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9230	CONCLUSIONS
9231	OBJECTIVE
9232	METHODS
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9250	CONCLUSIONS
9251	RESULTS
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9253	BACKGROUND
9254	BACKGROUND
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9256	METHODS
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9260	METHODS
9261	RESULTS
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9264	RESULTS
9265	RESULTS
9266	CONCLUSIONS
9267	BACKGROUND
9268	OBJECTIVE
9269	METHODS
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9274	RESULTS
9275	RESULTS
9276	CONCLUSIONS
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9278	OBJECTIVE
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9280	OBJECTIVE
9281	METHODS
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9284	RESULTS
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9287	CONCLUSIONS
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9289	BACKGROUND
9290	OBJECTIVE
9291	METHODS
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9295	RESULTS
9296	RESULTS
9297	RESULTS
9298	CONCLUSIONS
9299	CONCLUSIONS
9300	OBJECTIVE
9301	METHODS
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9306	RESULTS
9307	RESULTS
9308	CONCLUSIONS
9309	BACKGROUND
9310	CONCLUSIONS
9311	OBJECTIVE
9312	METHODS
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9315	METHODS
9316	METHODS
9317	RESULTS
9318	CONCLUSIONS
9319	CONCLUSIONS
9320	OBJECTIVE
9321	METHODS
9322	METHODS
9323	METHODS
9324	METHODS
9325	METHODS
9326	RESULTS
9327	CONCLUSIONS
9328	BACKGROUND
9329	CONCLUSIONS
9330	OBJECTIVE
9331	METHODS
9332	RESULTS
9333	RESULTS
9334	RESULTS
9335	CONCLUSIONS
9336	BACKGROUND
9337	BACKGROUND
9338	BACKGROUND
9339	BACKGROUND
9340	OBJECTIVE
9341	METHODS
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9346	RESULTS
9347	RESULTS
9348	RESULTS
9349	RESULTS
9350	CONCLUSIONS
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9352	CONCLUSIONS
9353	OBJECTIVE
9354	METHODS
9355	METHODS
9356	METHODS
9357	METHODS
9358	RESULTS
9359	RESULTS
9360	RESULTS
9361	CONCLUSIONS
9362	BACKGROUND
9363	CONCLUSIONS
9364	OBJECTIVE
9365	METHODS
9366	METHODS
9367	METHODS
9368	RESULTS
9369	RESULTS
9370	RESULTS
9371	RESULTS
9372	RESULTS
9373	RESULTS
9374	RESULTS
9375	RESULTS
9376	CONCLUSIONS
9377	CONCLUSIONS
9378	BACKGROUND
9379	BACKGROUND
9380	BACKGROUND
9381	OBJECTIVE
9382	METHODS
9383	RESULTS
9384	RESULTS
9385	RESULTS
9386	CONCLUSIONS
9387	BACKGROUND
9388	BACKGROUND
9389	BACKGROUND
9390	BACKGROUND
9391	METHODS
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9393	METHODS
9394	RESULTS
9395	RESULTS
9396	RESULTS
9397	RESULTS
9398	RESULTS
9399	BACKGROUND
9400	CONCLUSIONS
9401	OBJECTIVE
9402	METHODS
9403	METHODS
9404	METHODS
9405	METHODS
9406	METHODS
9407	METHODS
9408	METHODS
9409	METHODS
9410	RESULTS
9411	RESULTS
9412	RESULTS
9413	RESULTS
9414	RESULTS
9415	CONCLUSIONS
9416	OBJECTIVE
9417	METHODS
9418	METHODS
9419	RESULTS
9420	RESULTS
9421	RESULTS
9422	RESULTS
9423	CONCLUSIONS
9424	CONCLUSIONS
9425	OBJECTIVE
9426	METHODS
9427	METHODS
9428	METHODS
9429	METHODS
9430	RESULTS
9431	RESULTS
9432	RESULTS
9433	RESULTS
9434	RESULTS
9435	RESULTS
9436	CONCLUSIONS
9437	OBJECTIVE
9438	METHODS
9439	METHODS
9440	METHODS
9441	METHODS
9442	METHODS
9443	METHODS
9444	METHODS
9445	METHODS
9446	METHODS
9447	RESULTS
9448	RESULTS
9449	CONCLUSIONS
9450	OBJECTIVE
9451	METHODS
9452	METHODS
9453	METHODS
9454	RESULTS
9455	RESULTS
9456	RESULTS
9457	RESULTS
9458	CONCLUSIONS
9459	BACKGROUND
9460	BACKGROUND
9461	BACKGROUND
9462	METHODS
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9464	METHODS
9465	METHODS
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9467	METHODS
9468	METHODS
9469	RESULTS
9470	RESULTS
9471	RESULTS
9472	CONCLUSIONS
9473	BACKGROUND
9474	METHODS
9475	METHODS
9476	METHODS
9477	METHODS
9478	RESULTS
9479	RESULTS
9480	RESULTS
9481	RESULTS
9482	CONCLUSIONS
9483	BACKGROUND
9484	BACKGROUND
9485	OBJECTIVE
9486	METHODS
9487	OBJECTIVE
9488	METHODS
9489	RESULTS
9490	RESULTS
9491	CONCLUSIONS
9492	CONCLUSIONS
9493	CONCLUSIONS
9494	BACKGROUND
9495	OBJECTIVE
9496	METHODS
9497	METHODS
9498	METHODS
9499	CONCLUSIONS
9500	CONCLUSIONS
9501	RESULTS
9502	BACKGROUND
9503	BACKGROUND
9504	METHODS
9505	METHODS
9506	METHODS
9507	METHODS
9508	METHODS
9509	METHODS
9510	METHODS
9511	METHODS
9512	RESULTS
9513	RESULTS
9514	RESULTS
9515	RESULTS
9516	CONCLUSIONS
9517	CONCLUSIONS
9518	BACKGROUND
9519	OBJECTIVE
9520	METHODS
9521	METHODS
9522	METHODS
9523	RESULTS
9524	RESULTS
9525	RESULTS
9526	RESULTS
9527	CONCLUSIONS
9528	CONCLUSIONS
9529	BACKGROUND
9530	BACKGROUND
9531	METHODS
9532	METHODS
9533	METHODS
9534	RESULTS
9535	RESULTS
9536	RESULTS
9537	CONCLUSIONS
9538	CONCLUSIONS
9539	CONCLUSIONS
9540	BACKGROUND
9541	BACKGROUND
9542	BACKGROUND
9543	METHODS
9544	METHODS
9545	METHODS
9546	METHODS
9547	METHODS
9548	BACKGROUND
9549	CONCLUSIONS
9550	BACKGROUND
9551	BACKGROUND
9552	OBJECTIVE
9553	METHODS
9554	METHODS
9555	METHODS
9556	METHODS
9557	RESULTS
9558	RESULTS
9559	RESULTS
9560	RESULTS
9561	RESULTS
9562	CONCLUSIONS
9563	OBJECTIVE
9564	METHODS
9565	METHODS
9566	METHODS
9567	METHODS
9568	RESULTS
9569	RESULTS
9570	RESULTS
9571	RESULTS
9572	CONCLUSIONS
9573	BACKGROUND
9574	CONCLUSIONS
9575	OBJECTIVE
9576	METHODS
9577	METHODS
9578	METHODS
9579	RESULTS
9580	RESULTS
9581	RESULTS
9582	RESULTS
9583	CONCLUSIONS
9584	BACKGROUND
9585	BACKGROUND
9586	METHODS
9587	METHODS
9588	METHODS
9589	RESULTS
9590	RESULTS
9591	RESULTS
9592	RESULTS
9593	RESULTS
9594	RESULTS
9595	RESULTS
9596	BACKGROUND
9597	BACKGROUND
9598	OBJECTIVE
9599	METHODS
9600	METHODS
9601	METHODS
9602	RESULTS
9603	RESULTS
9604	RESULTS
9605	CONCLUSIONS
9606	CONCLUSIONS
9607	OBJECTIVE
9608	METHODS
9609	METHODS
9610	METHODS
9611	RESULTS
9612	RESULTS
9613	RESULTS
9614	RESULTS
9615	RESULTS
9616	CONCLUSIONS
9617	BACKGROUND
9618	BACKGROUND
9619	METHODS
9620	METHODS
9621	RESULTS
9622	RESULTS
9623	RESULTS
9624	RESULTS
9625	CONCLUSIONS
9626	CONCLUSIONS
9627	BACKGROUND
9628	BACKGROUND
9629	METHODS
9630	BACKGROUND
9631	RESULTS
9632	RESULTS
9633	CONCLUSIONS
9634	BACKGROUND
9635	CONCLUSIONS
9636	BACKGROUND
9637	METHODS
9638	RESULTS
9639	CONCLUSIONS
9640	BACKGROUND
9641	OBJECTIVE
9642	METHODS
9643	METHODS
9644	RESULTS
9645	RESULTS
9646	CONCLUSIONS
9647	RESULTS
9648	RESULTS
9649	RESULTS
9650	BACKGROUND
9651	BACKGROUND
9652	BACKGROUND
9653	OBJECTIVE
9654	METHODS
9655	METHODS
9656	METHODS
9657	RESULTS
9658	RESULTS
9659	RESULTS
9660	RESULTS
9661	RESULTS
9662	CONCLUSIONS
9663	BACKGROUND
9664	BACKGROUND
9665	BACKGROUND
9666	OBJECTIVE
9667	OBJECTIVE
9668	RESULTS
9669	RESULTS
9670	RESULTS
9671	CONCLUSIONS
9672	BACKGROUND
9673	OBJECTIVE
9674	OBJECTIVE
9675	METHODS
9676	METHODS
9677	METHODS
9678	METHODS
9679	RESULTS
9680	RESULTS
9681	RESULTS
9682	RESULTS
9683	RESULTS
9684	RESULTS
9685	CONCLUSIONS
9686	CONCLUSIONS
9687	OBJECTIVE
9688	OBJECTIVE
9689	METHODS
9690	METHODS
9691	METHODS
9692	RESULTS
9693	RESULTS
9694	RESULTS
9695	CONCLUSIONS
9696	CONCLUSIONS
9697	METHODS
9698	BACKGROUND
9699	BACKGROUND
9700	OBJECTIVE
9701	METHODS
9702	METHODS
9703	RESULTS
9704	RESULTS
9705	RESULTS
9706	RESULTS
9707	CONCLUSIONS
9708	CONCLUSIONS
9709	OBJECTIVE
9710	METHODS
9711	METHODS
9712	METHODS
9713	METHODS
9714	METHODS
9715	METHODS
9716	RESULTS
9717	RESULTS
9718	CONCLUSIONS
9719	CONCLUSIONS
9720	OBJECTIVE
9721	METHODS
9722	RESULTS
9723	METHODS
9724	METHODS
9725	RESULTS
9726	RESULTS
9727	RESULTS
9728	RESULTS
9729	RESULTS
9730	RESULTS
9731	RESULTS
9732	RESULTS
9733	RESULTS
9734	RESULTS
9735	RESULTS
9736	CONCLUSIONS
9737	OBJECTIVE
9738	METHODS
9739	METHODS
9740	RESULTS
9741	RESULTS
9742	RESULTS
9743	RESULTS
9744	CONCLUSIONS
9745	METHODS
9746	OBJECTIVE
9747	METHODS
9748	METHODS
9749	RESULTS
9750	RESULTS
9751	RESULTS
9752	RESULTS
9753	CONCLUSIONS
9754	OBJECTIVE
9755	METHODS
9756	METHODS
9757	METHODS
9758	RESULTS
9759	RESULTS
9760	CONCLUSIONS
9761	CONCLUSIONS
9762	CONCLUSIONS
9763	METHODS
9764	BACKGROUND
9765	BACKGROUND
9766	METHODS
9767	METHODS
9768	RESULTS
9769	RESULTS
9770	RESULTS
9771	RESULTS
9772	CONCLUSIONS
9773	CONCLUSIONS
9774	BACKGROUND
9775	BACKGROUND
9776	METHODS
9777	METHODS
9778	METHODS
9779	RESULTS
9780	RESULTS
9781	RESULTS
9782	RESULTS
9783	CONCLUSIONS
9784	CONCLUSIONS
9785	BACKGROUND
9786	BACKGROUND
9787	OBJECTIVE
9788	METHODS
9789	METHODS
9790	METHODS
9791	METHODS
9792	RESULTS
9793	RESULTS
9794	RESULTS
9795	RESULTS
9796	OBJECTIVE
9797	METHODS
9798	RESULTS
9799	RESULTS
9800	CONCLUSIONS
9801	CONCLUSIONS
9802	BACKGROUND
9803	BACKGROUND
9804	BACKGROUND
9805	METHODS
9806	METHODS
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9808	RESULTS
9809	RESULTS
9810	RESULTS
9811	CONCLUSIONS
9812	CONCLUSIONS
9813	BACKGROUND
9814	OBJECTIVE
9815	METHODS
9816	METHODS
9817	RESULTS
9818	RESULTS
9819	RESULTS
9820	CONCLUSIONS
9821	CONCLUSIONS
9822	BACKGROUND
9823	BACKGROUND
9824	BACKGROUND
9825	BACKGROUND
9826	OBJECTIVE
9827	METHODS
9828	METHODS
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9831	RESULTS
9832	CONCLUSIONS
9833	CONCLUSIONS
9834	BACKGROUND
9835	RESULTS
9836	OBJECTIVE
9837	METHODS
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9840	METHODS
9841	METHODS
9842	RESULTS
9843	RESULTS
9844	CONCLUSIONS
9845	CONCLUSIONS
9846	CONCLUSIONS
9847	BACKGROUND
9848	OBJECTIVE
9849	METHODS
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9853	RESULTS
9854	CONCLUSIONS
9855	OBJECTIVE
9856	METHODS
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9860	METHODS
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9863	RESULTS
9864	RESULTS
9865	CONCLUSIONS
9866	OBJECTIVE
9867	METHODS
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9869	METHODS
9870	METHODS
9871	RESULTS
9872	RESULTS
9873	CONCLUSIONS
9874	BACKGROUND
9875	CONCLUSIONS
9876	CONCLUSIONS
9877	OBJECTIVE
9878	METHODS
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9884	RESULTS
9885	RESULTS
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9887	RESULTS
9888	CONCLUSIONS
9889	CONCLUSIONS
9890	BACKGROUND
9891	BACKGROUND
9892	BACKGROUND
9893	METHODS
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9895	METHODS
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9898	RESULTS
9899	CONCLUSIONS
9900	BACKGROUND
9901	CONCLUSIONS
9902	RESULTS
9903	CONCLUSIONS
9904	METHODS
9905	METHODS
9906	RESULTS
9907	RESULTS
9908	CONCLUSIONS
9909	BACKGROUND
9910	OBJECTIVE
9911	METHODS
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9917	RESULTS
9918	CONCLUSIONS
9919	OBJECTIVE
9920	METHODS
9921	METHODS
9922	METHODS
9923	RESULTS
9924	RESULTS
9925	RESULTS
9926	RESULTS
9927	RESULTS
9928	CONCLUSIONS
9929	CONCLUSIONS
9930	OBJECTIVE
9931	METHODS
9932	METHODS
9933	METHODS
9934	METHODS
9935	METHODS
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9937	METHODS
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9939	METHODS
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9941	RESULTS
9942	RESULTS
9943	RESULTS
9944	CONCLUSIONS
9945	OBJECTIVE
9946	METHODS
9947	METHODS
9948	METHODS
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9951	METHODS
9952	METHODS
9953	METHODS
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9955	METHODS
9956	RESULTS
9957	RESULTS
9958	RESULTS
9959	CONCLUSIONS
9960	BACKGROUND
9961	BACKGROUND
9962	CONCLUSIONS
9963	CONCLUSIONS
9964	RESULTS
9965	OBJECTIVE
9966	METHODS
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9970	RESULTS
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9972	RESULTS
9973	RESULTS
9974	CONCLUSIONS
9975	RESULTS
9976	OBJECTIVE
9977	METHODS
9978	METHODS
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9980	METHODS
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9982	RESULTS
9983	RESULTS
9984	RESULTS
9985	RESULTS
9986	RESULTS
9987	CONCLUSIONS
9988	CONCLUSIONS
9989	CONCLUSIONS
9990	OBJECTIVE
9991	METHODS
9992	METHODS
9993	METHODS
9994	METHODS
9995	RESULTS
9996	RESULTS
9997	CONCLUSIONS
9998	RESULTS
9999	CONCLUSIONS
10000	CONCLUSIONS
10001	BACKGROUND
10002	RESULTS
10003	METHODS
10004	OBJECTIVE
10005	OBJECTIVE
10006	CONCLUSIONS
10007	CONCLUSIONS
10008	OBJECTIVE
10009	OBJECTIVE
10010	METHODS
10011	CONCLUSIONS
10012	CONCLUSIONS
10013	BACKGROUND
10014	OBJECTIVE
10015	METHODS
10016	METHODS
10017	METHODS
10018	RESULTS
10019	RESULTS
10020	RESULTS
10021	RESULTS
10022	CONCLUSIONS
10023	BACKGROUND
10024	OBJECTIVE
10025	METHODS
10026	METHODS
10027	RESULTS
10028	RESULTS
10029	RESULTS
10030	RESULTS
10031	CONCLUSIONS
10032	CONCLUSIONS
10033	BACKGROUND
10034	BACKGROUND
10035	METHODS
10036	METHODS
10037	METHODS
10038	RESULTS
10039	RESULTS
10040	RESULTS
10041	RESULTS
10042	RESULTS
10043	CONCLUSIONS
10044	CONCLUSIONS
10045	OBJECTIVE
10046	METHODS
10047	METHODS
10048	METHODS
10049	METHODS
10050	RESULTS
10051	RESULTS
10052	RESULTS
10053	RESULTS
10054	CONCLUSIONS
10055	OBJECTIVE
10056	METHODS
10057	RESULTS
10058	RESULTS
10059	RESULTS
10060	RESULTS
10061	RESULTS
10062	RESULTS
10063	RESULTS
10064	RESULTS
10065	CONCLUSIONS
10066	BACKGROUND
10067	OBJECTIVE
10068	METHODS
10069	METHODS
10070	METHODS
10071	RESULTS
10072	RESULTS
10073	RESULTS
10074	RESULTS
10075	CONCLUSIONS
10076	OBJECTIVE
10077	METHODS
10078	METHODS
10079	METHODS
10080	METHODS
10081	METHODS
10082	METHODS
10083	RESULTS
10084	RESULTS
10085	RESULTS
10086	RESULTS
10087	CONCLUSIONS
10088	CONCLUSIONS
10089	OBJECTIVE
10090	METHODS
10091	METHODS
10092	METHODS
10093	RESULTS
10094	RESULTS
10095	RESULTS
10096	RESULTS
10097	RESULTS
10098	CONCLUSIONS
10099	CONCLUSIONS
10100	BACKGROUND
10101	OBJECTIVE
10102	METHODS
10103	METHODS
10104	METHODS
10105	RESULTS
10106	RESULTS
10107	CONCLUSIONS
10108	CONCLUSIONS
10109	CONCLUSIONS
10110	CONCLUSIONS
10111	BACKGROUND
10112	BACKGROUND
10113	BACKGROUND
10114	RESULTS
10115	RESULTS
10116	RESULTS
10117	RESULTS
10118	RESULTS
10119	CONCLUSIONS
10120	BACKGROUND
10121	OBJECTIVE
10122	METHODS
10123	METHODS
10124	METHODS
10125	METHODS
10126	METHODS
10127	METHODS
10128	METHODS
10129	RESULTS
10130	RESULTS
10131	CONCLUSIONS
10132	RESULTS
10133	CONCLUSIONS
10134	BACKGROUND
10135	METHODS
10136	METHODS
10137	RESULTS
10138	RESULTS
10139	RESULTS
10140	CONCLUSIONS
10141	CONCLUSIONS
10142	OBJECTIVE
10143	METHODS
10144	METHODS
10145	RESULTS
10146	RESULTS
10147	RESULTS
10148	CONCLUSIONS
10149	BACKGROUND
10150	BACKGROUND
10151	OBJECTIVE
10152	METHODS
10153	METHODS
10154	RESULTS
10155	RESULTS
10156	RESULTS
10157	CONCLUSIONS
10158	CONCLUSIONS
10159	BACKGROUND
10160	METHODS
10161	METHODS
10162	METHODS
10163	METHODS
10164	METHODS
10165	METHODS
10166	RESULTS
10167	RESULTS
10168	RESULTS
10169	CONCLUSIONS
10170	BACKGROUND
10171	CONCLUSIONS
10172	OBJECTIVE
10173	METHODS
10174	METHODS
10175	RESULTS
10176	RESULTS
10177	CONCLUSIONS
10178	CONCLUSIONS
10179	CONCLUSIONS
10180	BACKGROUND
10181	BACKGROUND
10182	BACKGROUND
10183	BACKGROUND
10184	CONCLUSIONS
10185	METHODS
10186	METHODS
10187	METHODS
10188	METHODS
10189	METHODS
10190	METHODS
10191	RESULTS
10192	METHODS
10193	RESULTS
10194	CONCLUSIONS
10195	BACKGROUND
10196	BACKGROUND
10197	OBJECTIVE
10198	METHODS
10199	METHODS
10200	METHODS
10201	CONCLUSIONS
10202	RESULTS
10203	RESULTS
10204	RESULTS
10205	CONCLUSIONS
10206	CONCLUSIONS
10207	OBJECTIVE
10208	METHODS
10209	METHODS
10210	METHODS
10211	METHODS
10212	METHODS
10213	RESULTS
10214	RESULTS
10215	RESULTS
10216	RESULTS
10217	RESULTS
10218	RESULTS
10219	CONCLUSIONS
10220	BACKGROUND
10221	OBJECTIVE
10222	METHODS
10223	METHODS
10224	METHODS
10225	METHODS
10226	METHODS
10227	METHODS
10228	METHODS
10229	RESULTS
10230	RESULTS
10231	RESULTS
10232	RESULTS
10233	CONCLUSIONS
10234	CONCLUSIONS
10235	OBJECTIVE
10236	METHODS
10237	METHODS
10238	METHODS
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10240	METHODS
10241	RESULTS
10242	RESULTS
10243	RESULTS
10244	RESULTS
10245	CONCLUSIONS
10246	CONCLUSIONS
10247	BACKGROUND
10248	OBJECTIVE
10249	METHODS
10250	METHODS
10251	METHODS
10252	METHODS
10253	METHODS
10254	METHODS
10255	METHODS
10256	METHODS
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10258	RESULTS
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10260	RESULTS
10261	RESULTS
10262	RESULTS
10263	RESULTS
10264	CONCLUSIONS
10265	RESULTS
10266	CONCLUSIONS
10267	OBJECTIVE
10268	METHODS
10269	METHODS
10270	METHODS
10271	METHODS
10272	METHODS
10273	METHODS
10274	RESULTS
10275	RESULTS
10276	METHODS
10277	RESULTS
10278	RESULTS
10279	CONCLUSIONS
10280	CONCLUSIONS
10281	BACKGROUND
10282	BACKGROUND
10283	METHODS
10284	METHODS
10285	METHODS
10286	METHODS
10287	METHODS
10288	METHODS
10289	METHODS
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10291	RESULTS
10292	RESULTS
10293	RESULTS
10294	CONCLUSIONS
10295	OBJECTIVE
10296	METHODS
10297	METHODS
10298	METHODS
10299	METHODS
10300	METHODS
10301	RESULTS
10302	RESULTS
10303	RESULTS
10304	RESULTS
10305	RESULTS
10306	CONCLUSIONS
10307	OBJECTIVE
10308	METHODS
10309	METHODS
10310	METHODS
10311	METHODS
10312	METHODS
10313	METHODS
10314	METHODS
10315	RESULTS
10316	RESULTS
10317	CONCLUSIONS
10318	CONCLUSIONS
10319	OBJECTIVE
10320	METHODS
10321	METHODS
10322	METHODS
10323	METHODS
10324	METHODS
10325	METHODS
10326	METHODS
10327	RESULTS
10328	RESULTS
10329	RESULTS
10330	RESULTS
10331	CONCLUSIONS
10332	CONCLUSIONS
10333	BACKGROUND
10334	BACKGROUND
10335	RESULTS
10336	BACKGROUND
10337	METHODS
10338	METHODS
10339	RESULTS
10340	RESULTS
10341	RESULTS
10342	RESULTS
10343	RESULTS
10344	CONCLUSIONS
10345	CONCLUSIONS
10346	BACKGROUND
10347	BACKGROUND
10348	OBJECTIVE
10349	METHODS
10350	METHODS
10351	METHODS
10352	METHODS
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10354	RESULTS
10355	RESULTS
10356	RESULTS
10357	RESULTS
10358	RESULTS
10359	RESULTS
10360	RESULTS
10361	RESULTS
10362	CONCLUSIONS
10363	RESULTS
10364	BACKGROUND
10365	BACKGROUND
10366	OBJECTIVE
10367	METHODS
10368	METHODS
10369	METHODS
10370	METHODS
10371	RESULTS
10372	RESULTS
10373	RESULTS
10374	RESULTS
10375	RESULTS
10376	RESULTS
10377	RESULTS
10378	RESULTS
10379	CONCLUSIONS
10380	CONCLUSIONS
10381	BACKGROUND
10382	OBJECTIVE
10383	RESULTS
10384	RESULTS
10385	RESULTS
10386	RESULTS
10387	CONCLUSIONS
10388	CONCLUSIONS
10389	BACKGROUND
10390	OBJECTIVE
10391	METHODS
10392	METHODS
10393	METHODS
10394	RESULTS
10395	RESULTS
10396	RESULTS
10397	RESULTS
10398	RESULTS
10399	RESULTS
10400	CONCLUSIONS
10401	CONCLUSIONS
10402	OBJECTIVE
10403	METHODS
10404	METHODS
10405	METHODS
10406	CONCLUSIONS
10407	METHODS
10408	METHODS
10409	METHODS
10410	OBJECTIVE
10411	CONCLUSIONS
10412	CONCLUSIONS
10413	CONCLUSIONS
10414	RESULTS
10415	RESULTS
10416	CONCLUSIONS
10417	CONCLUSIONS
10418	CONCLUSIONS
10419	METHODS
10420	METHODS
10421	METHODS
10422	CONCLUSIONS
10423	RESULTS
10424	RESULTS
10425	CONCLUSIONS
10426	CONCLUSIONS
10427	OBJECTIVE
10428	METHODS
10429	METHODS
10430	RESULTS
10431	RESULTS
10432	RESULTS
10433	RESULTS
10434	RESULTS
10435	CONCLUSIONS
10436	CONCLUSIONS
10437	BACKGROUND
10438	BACKGROUND
10439	METHODS
10440	RESULTS
10441	METHODS
10442	METHODS
10443	METHODS
10444	RESULTS
10445	RESULTS
10446	RESULTS
10447	RESULTS
10448	RESULTS
10449	RESULTS
10450	CONCLUSIONS
10451	OBJECTIVE
10452	BACKGROUND
10453	OBJECTIVE
10454	METHODS
10455	METHODS
10456	METHODS
10457	METHODS
10458	METHODS
10459	RESULTS
10460	RESULTS
10461	RESULTS
10462	RESULTS
10463	RESULTS
10464	RESULTS
10465	RESULTS
10466	RESULTS
10467	RESULTS
10468	CONCLUSIONS
10469	RESULTS
10470	BACKGROUND
10471	OBJECTIVE
10472	METHODS
10473	METHODS
10474	METHODS
10475	METHODS
10476	METHODS
10477	RESULTS
10478	RESULTS
10479	RESULTS
10480	CONCLUSIONS
10481	CONCLUSIONS
10482	CONCLUSIONS
10483	METHODS
10484	OBJECTIVE
10485	BACKGROUND
10486	BACKGROUND
10487	METHODS
10488	METHODS
10489	METHODS
10490	METHODS
10491	METHODS
10492	METHODS
10493	METHODS
10494	METHODS
10495	RESULTS
10496	RESULTS
10497	RESULTS
10498	CONCLUSIONS
10499	CONCLUSIONS
10500	BACKGROUND
10501	BACKGROUND
10502	METHODS
10503	METHODS
10504	RESULTS
10505	RESULTS
10506	RESULTS
10507	RESULTS
10508	RESULTS
10509	RESULTS
10510	RESULTS
10511	CONCLUSIONS
10512	OBJECTIVE
10513	METHODS
10514	METHODS
10515	METHODS
10516	METHODS
10517	METHODS
10518	RESULTS
10519	RESULTS
10520	RESULTS
10521	RESULTS
10522	CONCLUSIONS
10523	CONCLUSIONS
10524	CONCLUSIONS
10525	BACKGROUND
10526	BACKGROUND
10527	METHODS
10528	METHODS
10529	METHODS
10530	RESULTS
10531	RESULTS
10532	RESULTS
10533	RESULTS
10534	RESULTS
10535	RESULTS
10536	CONCLUSIONS
10537	RESULTS
10538	CONCLUSIONS
10539	OBJECTIVE
10540	BACKGROUND
10541	BACKGROUND
10542	CONCLUSIONS
10543	OBJECTIVE
10544	METHODS
10545	METHODS
10546	RESULTS
10547	RESULTS
10548	CONCLUSIONS
10549	CONCLUSIONS
10550	OBJECTIVE
10551	METHODS
10552	METHODS
10553	METHODS
10554	RESULTS
10555	RESULTS
10556	CONCLUSIONS
10557	CONCLUSIONS
10558	OBJECTIVE
10559	METHODS
10560	METHODS
10561	CONCLUSIONS
10562	RESULTS
10563	CONCLUSIONS
10564	RESULTS
10565	CONCLUSIONS
10566	RESULTS
10567	CONCLUSIONS
10568	BACKGROUND
10569	BACKGROUND
10570	RESULTS
10571	METHODS
10572	RESULTS
10573	RESULTS
10574	RESULTS
10575	RESULTS
10576	RESULTS
10577	CONCLUSIONS
10578	OBJECTIVE
10579	METHODS
10580	METHODS
10581	METHODS
10582	METHODS
10583	RESULTS
10584	RESULTS
10585	RESULTS
10586	RESULTS
10587	CONCLUSIONS
10588	OBJECTIVE
10589	METHODS
10590	METHODS
10591	METHODS
10592	RESULTS
10593	CONCLUSIONS
10594	OBJECTIVE
10595	METHODS
10596	METHODS
10597	METHODS
10598	METHODS
10599	METHODS
10600	RESULTS
10601	RESULTS
10602	RESULTS
10603	RESULTS
10604	RESULTS
10605	CONCLUSIONS
10606	OBJECTIVE
10607	METHODS
10608	METHODS
10609	METHODS
10610	METHODS
10611	METHODS
10612	METHODS
10613	METHODS
10614	METHODS
10615	RESULTS
10616	RESULTS
10617	RESULTS
10618	CONCLUSIONS
10619	BACKGROUND
10620	BACKGROUND
10621	METHODS
10622	METHODS
10623	METHODS
10624	METHODS
10625	RESULTS
10626	RESULTS
10627	RESULTS
10628	RESULTS
10629	CONCLUSIONS
10630	CONCLUSIONS
10631	OBJECTIVE
10632	METHODS
10633	METHODS
10634	METHODS
10635	RESULTS
10636	CONCLUSIONS
10637	OBJECTIVE
10638	CONCLUSIONS
10639	CONCLUSIONS
10640	METHODS
10641	BACKGROUND
10642	OBJECTIVE
10643	METHODS
10644	METHODS
10645	METHODS
10646	RESULTS
10647	RESULTS
10648	CONCLUSIONS
10649	CONCLUSIONS
10650	OBJECTIVE
10651	METHODS
10652	METHODS
10653	RESULTS
10654	RESULTS
10655	RESULTS
10656	RESULTS
10657	RESULTS
10658	CONCLUSIONS
10659	BACKGROUND
10660	BACKGROUND
10661	BACKGROUND
10662	BACKGROUND
10663	BACKGROUND
10664	RESULTS
10665	RESULTS
10666	RESULTS
10667	METHODS
10668	RESULTS
10669	RESULTS
10670	RESULTS
10671	CONCLUSIONS
10672	CONCLUSIONS
10673	BACKGROUND
10674	BACKGROUND
10675	BACKGROUND
10676	OBJECTIVE
10677	METHODS
10678	METHODS
10679	METHODS
10680	RESULTS
10681	RESULTS
10682	OBJECTIVE
10683	OBJECTIVE
10684	METHODS
10685	METHODS
10686	METHODS
10687	METHODS
10688	RESULTS
10689	RESULTS
10690	RESULTS
10691	RESULTS
10692	CONCLUSIONS
10693	CONCLUSIONS
10694	METHODS
10695	BACKGROUND
10696	BACKGROUND
10697	METHODS
10698	RESULTS
10699	RESULTS
10700	RESULTS
10701	RESULTS
10702	RESULTS
10703	RESULTS
10704	CONCLUSIONS
10705	BACKGROUND
10706	BACKGROUND
10707	BACKGROUND
10708	OBJECTIVE
10709	METHODS
10710	METHODS
10711	METHODS
10712	METHODS
10713	METHODS
10714	RESULTS
10715	RESULTS
10716	RESULTS
10717	CONCLUSIONS
10718	CONCLUSIONS
10719	BACKGROUND
10720	OBJECTIVE
10721	OBJECTIVE
10722	METHODS
10723	METHODS
10724	METHODS
10725	RESULTS
10726	RESULTS
10727	RESULTS
10728	CONCLUSIONS
10729	CONCLUSIONS
10730	OBJECTIVE
10731	METHODS
10732	METHODS
10733	METHODS
10734	METHODS
10735	RESULTS
10736	RESULTS
10737	RESULTS
10738	RESULTS
10739	RESULTS
10740	CONCLUSIONS
10741	CONCLUSIONS
10742	BACKGROUND
10743	METHODS
10744	METHODS
10745	METHODS
10746	RESULTS
10747	RESULTS
10748	RESULTS
10749	RESULTS
10750	RESULTS
10751	RESULTS
10752	RESULTS
10753	CONCLUSIONS
10754	RESULTS
10755	BACKGROUND
10756	BACKGROUND
10757	BACKGROUND
10758	METHODS
10759	METHODS
10760	METHODS
10761	METHODS
10762	RESULTS
10763	RESULTS
10764	RESULTS
10765	RESULTS
10766	CONCLUSIONS
10767	CONCLUSIONS
10768	OBJECTIVE
10769	METHODS
10770	METHODS
10771	METHODS
10772	RESULTS
10773	RESULTS
10774	RESULTS
10775	RESULTS
10776	CONCLUSIONS
10777	BACKGROUND
10778	BACKGROUND
10779	METHODS
10780	METHODS
10781	RESULTS
10782	RESULTS
10783	RESULTS
10784	RESULTS
10785	CONCLUSIONS
10786	CONCLUSIONS
10787	OBJECTIVE
10788	METHODS
10789	METHODS
10790	METHODS
10791	METHODS
10792	METHODS
10793	METHODS
10794	METHODS
10795	METHODS
10796	RESULTS
10797	CONCLUSIONS
10798	RESULTS
10799	CONCLUSIONS
10800	OBJECTIVE
10801	METHODS
10802	METHODS
10803	METHODS
10804	METHODS
10805	METHODS
10806	METHODS
10807	RESULTS
10808	RESULTS
10809	CONCLUSIONS
10810	BACKGROUND
10811	BACKGROUND
10812	BACKGROUND
10813	METHODS
10814	CONCLUSIONS
10815	RESULTS
10816	RESULTS
10817	RESULTS
10818	CONCLUSIONS
10819	CONCLUSIONS
10820	BACKGROUND
10821	OBJECTIVE
10822	METHODS
10823	METHODS
10824	METHODS
10825	METHODS
10826	METHODS
10827	RESULTS
10828	RESULTS
10829	RESULTS
10830	RESULTS
10831	RESULTS
10832	CONCLUSIONS
10833	CONCLUSIONS
10834	OBJECTIVE
10835	METHODS
10836	METHODS
10837	RESULTS
10838	RESULTS
10839	RESULTS
10840	CONCLUSIONS
10841	BACKGROUND
10842	METHODS
10843	METHODS
10844	RESULTS
10845	METHODS
10846	METHODS
10847	METHODS
10848	RESULTS
10849	RESULTS
10850	RESULTS
10851	CONCLUSIONS
10852	CONCLUSIONS
10853	CONCLUSIONS
10854	BACKGROUND
10855	OBJECTIVE
10856	METHODS
10857	METHODS
10858	RESULTS
10859	RESULTS
10860	RESULTS
10861	CONCLUSIONS
10862	CONCLUSIONS
10863	OBJECTIVE
10864	BACKGROUND
10865	OBJECTIVE
10866	METHODS
10867	METHODS
10868	METHODS
10869	METHODS
10870	RESULTS
10871	RESULTS
10872	RESULTS
10873	RESULTS
10874	RESULTS
10875	RESULTS
10876	RESULTS
10877	CONCLUSIONS
10878	OBJECTIVE
10879	METHODS
10880	METHODS
10881	METHODS
10882	METHODS
10883	RESULTS
10884	RESULTS
10885	RESULTS
10886	CONCLUSIONS
10887	BACKGROUND
10888	OBJECTIVE
10889	METHODS
10890	METHODS
10891	METHODS
10892	RESULTS
10893	RESULTS
10894	RESULTS
10895	RESULTS
10896	RESULTS
10897	CONCLUSIONS
10898	OBJECTIVE
10899	METHODS
10900	METHODS
10901	METHODS
10902	METHODS
10903	METHODS
10904	RESULTS
10905	RESULTS
10906	RESULTS
10907	RESULTS
10908	RESULTS
10909	RESULTS
10910	RESULTS
10911	RESULTS
10912	BACKGROUND
10913	BACKGROUND
10914	RESULTS
10915	METHODS
10916	RESULTS
10917	RESULTS
10918	RESULTS
10919	RESULTS
10920	CONCLUSIONS
10921	CONCLUSIONS
10922	OBJECTIVE
10923	METHODS
10924	METHODS
10925	METHODS
10926	METHODS
10927	METHODS
10928	RESULTS
10929	RESULTS
10930	RESULTS
10931	RESULTS
10932	RESULTS
10933	CONCLUSIONS
10934	CONCLUSIONS
10935	BACKGROUND
10936	BACKGROUND
10937	METHODS
10938	RESULTS
10939	RESULTS
10940	RESULTS
10941	RESULTS
10942	RESULTS
10943	CONCLUSIONS
10944	CONCLUSIONS
10945	CONCLUSIONS
10946	BACKGROUND
10947	BACKGROUND
10948	METHODS
10949	METHODS
10950	METHODS
10951	METHODS
10952	METHODS
10953	METHODS
10954	METHODS
10955	METHODS
10956	METHODS
10957	METHODS
10958	METHODS
10959	BACKGROUND
10960	METHODS
10961	CONCLUSIONS
10962	BACKGROUND
10963	OBJECTIVE
10964	METHODS
10965	METHODS
10966	RESULTS
10967	RESULTS
10968	RESULTS
10969	RESULTS
10970	RESULTS
10971	RESULTS
10972	CONCLUSIONS
10973	BACKGROUND
10974	BACKGROUND
10975	OBJECTIVE
10976	METHODS
10977	METHODS
10978	METHODS
10979	METHODS
10980	METHODS
10981	METHODS
10982	RESULTS
10983	METHODS
10984	RESULTS
10985	CONCLUSIONS
10986	BACKGROUND
10987	BACKGROUND
10988	OBJECTIVE
10989	METHODS
10990	RESULTS
10991	RESULTS
10992	RESULTS
10993	RESULTS
10994	CONCLUSIONS
10995	RESULTS
10996	CONCLUSIONS
10997	RESULTS
10998	CONCLUSIONS
10999	BACKGROUND
11000	METHODS
11001	METHODS
11002	METHODS
11003	METHODS
11004	RESULTS
11005	RESULTS
11006	RESULTS
11007	RESULTS
11008	RESULTS
11009	RESULTS
11010	RESULTS
11011	CONCLUSIONS
11012	CONCLUSIONS
11013	OBJECTIVE
11014	METHODS
11015	METHODS
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11018	RESULTS
11019	RESULTS
11020	RESULTS
11021	RESULTS
11022	RESULTS
11023	RESULTS
11024	RESULTS
11025	CONCLUSIONS
11026	CONCLUSIONS
11027	OBJECTIVE
11028	METHODS
11029	METHODS
11030	METHODS
11031	METHODS
11032	METHODS
11033	RESULTS
11034	RESULTS
11035	RESULTS
11036	RESULTS
11037	RESULTS
11038	CONCLUSIONS
11039	BACKGROUND
11040	BACKGROUND
11041	METHODS
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11043	METHODS
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11045	CONCLUSIONS
11046	OBJECTIVE
11047	METHODS
11048	METHODS
11049	METHODS
11050	METHODS
11051	METHODS
11052	METHODS
11053	METHODS
11054	METHODS
11055	METHODS
11056	METHODS
11057	METHODS
11058	METHODS
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11060	RESULTS
11061	RESULTS
11062	RESULTS
11063	RESULTS
11064	RESULTS
11065	CONCLUSIONS
11066	OBJECTIVE
11067	METHODS
11068	METHODS
11069	METHODS
11070	METHODS
11071	METHODS
11072	METHODS
11073	RESULTS
11074	RESULTS
11075	METHODS
11076	RESULTS
11077	CONCLUSIONS
11078	CONCLUSIONS
11079	OBJECTIVE
11080	METHODS
11081	METHODS
11082	RESULTS
11083	RESULTS
11084	RESULTS
11085	RESULTS
11086	CONCLUSIONS
11087	OBJECTIVE
11088	METHODS
11089	METHODS
11090	METHODS
11091	RESULTS
11092	RESULTS
11093	RESULTS
11094	RESULTS
11095	RESULTS
11096	RESULTS
11097	CONCLUSIONS
11098	RESULTS
11099	CONCLUSIONS
11100	OBJECTIVE
11101	METHODS
11102	METHODS
11103	METHODS
11104	RESULTS
11105	RESULTS
11106	CONCLUSIONS
11107	BACKGROUND
11108	BACKGROUND
11109	CONCLUSIONS
11110	CONCLUSIONS
11111	OBJECTIVE
11112	METHODS
11113	METHODS
11114	METHODS
11115	METHODS
11116	METHODS
11117	RESULTS
11118	RESULTS
11119	RESULTS
11120	CONCLUSIONS
11121	RESULTS
11122	CONCLUSIONS
11123	BACKGROUND
11124	OBJECTIVE
11125	METHODS
11126	METHODS
11127	METHODS
11128	METHODS
11129	METHODS
11130	METHODS
11131	METHODS
11132	METHODS
11133	RESULTS
11134	CONCLUSIONS
11135	OBJECTIVE
11136	CONCLUSIONS
11137	CONCLUSIONS
11138	OBJECTIVE
11139	METHODS
11140	METHODS
11141	METHODS
11142	METHODS
11143	METHODS
11144	RESULTS
11145	RESULTS
11146	RESULTS
11147	RESULTS
11148	CONCLUSIONS
11149	RESULTS
11150	CONCLUSIONS
11151	BACKGROUND
11152	BACKGROUND
11153	OBJECTIVE
11154	METHODS
11155	METHODS
11156	METHODS
11157	METHODS
11158	RESULTS
11159	RESULTS
11160	RESULTS
11161	CONCLUSIONS
11162	CONCLUSIONS
11163	BACKGROUND
11164	BACKGROUND
11165	METHODS
11166	METHODS
11167	METHODS
11168	RESULTS
11169	RESULTS
11170	RESULTS
11171	RESULTS
11172	RESULTS
11173	CONCLUSIONS
11174	RESULTS
11175	CONCLUSIONS
11176	OBJECTIVE
11177	METHODS
11178	METHODS
11179	METHODS
11180	METHODS
11181	METHODS
11182	METHODS
11183	METHODS
11184	RESULTS
11185	RESULTS
11186	RESULTS
11187	RESULTS
11188	RESULTS
11189	RESULTS
11190	CONCLUSIONS
11191	CONCLUSIONS
11192	OBJECTIVE
11193	METHODS
11194	METHODS
11195	METHODS
11196	METHODS
11197	METHODS
11198	METHODS
11199	METHODS
11200	RESULTS
11201	RESULTS
11202	RESULTS
11203	RESULTS
11204	CONCLUSIONS
11205	CONCLUSIONS
11206	OBJECTIVE
11207	METHODS
11208	METHODS
11209	METHODS
11210	METHODS
11211	METHODS
11212	RESULTS
11213	RESULTS
11214	RESULTS
11215	RESULTS
11216	CONCLUSIONS
11217	CONCLUSIONS
11218	METHODS
11219	BACKGROUND
11220	METHODS
11221	METHODS
11222	METHODS
11223	METHODS
11224	METHODS
11225	RESULTS
11226	RESULTS
11227	RESULTS
11228	RESULTS
11229	RESULTS
11230	RESULTS
11231	RESULTS
11232	BACKGROUND
11233	BACKGROUND
11234	BACKGROUND
11235	METHODS
11236	METHODS
11237	METHODS
11238	CONCLUSIONS
11239	RESULTS
11240	CONCLUSIONS
11241	RESULTS
11242	CONCLUSIONS
11243	METHODS
11244	METHODS
11245	OBJECTIVE
11246	METHODS
11247	METHODS
11248	METHODS
11249	METHODS
11250	METHODS
11251	RESULTS
11252	RESULTS
11253	RESULTS
11254	CONCLUSIONS
11255	BACKGROUND
11256	BACKGROUND
11257	BACKGROUND
11258	BACKGROUND
11259	BACKGROUND
11260	BACKGROUND
11261	CONCLUSIONS
11262	METHODS
11263	METHODS
11264	METHODS
11265	METHODS
11266	METHODS
11267	METHODS
11268	METHODS
11269	METHODS
11270	CONCLUSIONS
11271	BACKGROUND
11272	BACKGROUND
11273	BACKGROUND
11274	BACKGROUND
11275	BACKGROUND
11276	OBJECTIVE
11277	METHODS
11278	METHODS
11279	METHODS
11280	METHODS
11281	METHODS
11282	METHODS
11283	METHODS
11284	RESULTS
11285	RESULTS
11286	RESULTS
11287	RESULTS
11288	CONCLUSIONS
11289	BACKGROUND
11290	OBJECTIVE
11291	METHODS
11292	METHODS
11293	METHODS
11294	METHODS
11295	METHODS
11296	RESULTS
11297	RESULTS
11298	RESULTS
11299	RESULTS
11300	RESULTS
11301	RESULTS
11302	RESULTS
11303	CONCLUSIONS
11304	BACKGROUND
11305	BACKGROUND
11306	OBJECTIVE
11307	METHODS
11308	METHODS
11309	METHODS
11310	METHODS
11311	METHODS
11312	METHODS
11313	METHODS
11314	RESULTS
11315	RESULTS
11316	RESULTS
11317	CONCLUSIONS
11318	BACKGROUND
11319	BACKGROUND
11320	BACKGROUND
11321	METHODS
11322	RESULTS
11323	RESULTS
11324	CONCLUSIONS
11325	CONCLUSIONS
11326	BACKGROUND
11327	OBJECTIVE
11328	METHODS
11329	METHODS
11330	METHODS
11331	METHODS
11332	RESULTS
11333	RESULTS
11334	RESULTS
11335	CONCLUSIONS
11336	BACKGROUND
11337	BACKGROUND
11338	OBJECTIVE
11339	METHODS
11340	METHODS
11341	METHODS
11342	METHODS
11343	RESULTS
11344	RESULTS
11345	RESULTS
11346	CONCLUSIONS
11347	BACKGROUND
11348	METHODS
11349	METHODS
11350	METHODS
11351	RESULTS
11352	RESULTS
11353	RESULTS
11354	RESULTS
11355	CONCLUSIONS
11356	CONCLUSIONS
11357	CONCLUSIONS
11358	BACKGROUND
11359	BACKGROUND
11360	BACKGROUND
11361	METHODS
11362	METHODS
11363	METHODS
11364	METHODS
11365	METHODS
11366	METHODS
11367	RESULTS
11368	RESULTS
11369	RESULTS
11370	RESULTS
11371	RESULTS
11372	RESULTS
11373	BACKGROUND
11374	OBJECTIVE
11375	OBJECTIVE
11376	METHODS
11377	METHODS
11378	METHODS
11379	METHODS
11380	METHODS
11381	METHODS
11382	RESULTS
11383	RESULTS
11384	CONCLUSIONS
11385	BACKGROUND
11386	BACKGROUND
11387	OBJECTIVE
11388	METHODS
11389	METHODS
11390	METHODS
11391	METHODS
11392	METHODS
11393	METHODS
11394	RESULTS
11395	RESULTS
11396	CONCLUSIONS
11397	CONCLUSIONS
11398	CONCLUSIONS
11399	OBJECTIVE
11400	METHODS
11401	METHODS
11402	METHODS
11403	METHODS
11404	METHODS
11405	RESULTS
11406	RESULTS
11407	RESULTS
11408	RESULTS
11409	CONCLUSIONS
11410	BACKGROUND
11411	METHODS
11412	METHODS
11413	METHODS
11414	METHODS
11415	METHODS
11416	RESULTS
11417	RESULTS
11418	RESULTS
11419	RESULTS
11420	RESULTS
11421	RESULTS
11422	CONCLUSIONS
11423	CONCLUSIONS
11424	BACKGROUND
11425	BACKGROUND
11426	BACKGROUND
11427	BACKGROUND
11428	BACKGROUND
11429	METHODS
11430	METHODS
11431	METHODS
11432	CONCLUSIONS
11433	CONCLUSIONS
11434	BACKGROUND
11435	BACKGROUND
11436	METHODS
11437	METHODS
11438	METHODS
11439	METHODS
11440	METHODS
11441	RESULTS
11442	RESULTS
11443	RESULTS
11444	RESULTS
11445	RESULTS
11446	BACKGROUND
11447	CONCLUSIONS
11448	BACKGROUND
11449	OBJECTIVE
11450	METHODS
11451	METHODS
11452	METHODS
11453	RESULTS
11454	RESULTS
11455	RESULTS
11456	CONCLUSIONS
11457	BACKGROUND
11458	BACKGROUND
11459	BACKGROUND
11460	BACKGROUND
11461	METHODS
11462	METHODS
11463	RESULTS
11464	RESULTS
11465	RESULTS
11466	RESULTS
11467	CONCLUSIONS
11468	CONCLUSIONS
11469	CONCLUSIONS
11470	BACKGROUND
11471	BACKGROUND
11472	BACKGROUND
11473	OBJECTIVE
11474	METHODS
11475	METHODS
11476	RESULTS
11477	RESULTS
11478	RESULTS
11479	RESULTS
11480	CONCLUSIONS
11481	CONCLUSIONS
11482	OBJECTIVE
11483	METHODS
11484	METHODS
11485	METHODS
11486	RESULTS
11487	RESULTS
11488	RESULTS
11489	RESULTS
11490	CONCLUSIONS
11491	BACKGROUND
11492	BACKGROUND
11493	OBJECTIVE
11494	METHODS
11495	METHODS
11496	METHODS
11497	METHODS
11498	METHODS
11499	RESULTS
11500	RESULTS
11501	CONCLUSIONS
11502	CONCLUSIONS
11503	OBJECTIVE
11504	METHODS
11505	RESULTS
11506	RESULTS
11507	RESULTS
11508	RESULTS
11509	RESULTS
11510	RESULTS
11511	CONCLUSIONS
11512	RESULTS
11513	RESULTS
11514	OBJECTIVE
11515	BACKGROUND
11516	CONCLUSIONS
11517	OBJECTIVE
11518	METHODS
11519	METHODS
11520	METHODS
11521	METHODS
11522	METHODS
11523	RESULTS
11524	RESULTS
11525	RESULTS
11526	RESULTS
11527	RESULTS
11528	CONCLUSIONS
11529	CONCLUSIONS
11530	CONCLUSIONS
11531	OBJECTIVE
11532	METHODS
11533	METHODS
11534	METHODS
11535	METHODS
11536	RESULTS
11537	RESULTS
11538	CONCLUSIONS
11539	CONCLUSIONS
11540	OBJECTIVE
11541	OBJECTIVE
11542	OBJECTIVE
11543	OBJECTIVE
11544	METHODS
11545	METHODS
11546	METHODS
11547	RESULTS
11548	RESULTS
11549	CONCLUSIONS
11550	CONCLUSIONS
11551	CONCLUSIONS
11552	BACKGROUND
11553	OBJECTIVE
11554	OBJECTIVE
11555	METHODS
11556	METHODS
11557	RESULTS
11558	METHODS
11559	RESULTS
11560	RESULTS
11561	RESULTS
11562	RESULTS
11563	RESULTS
11564	RESULTS
11565	RESULTS
11566	RESULTS
11567	RESULTS
11568	RESULTS
11569	CONCLUSIONS
11570	CONCLUSIONS
11571	BACKGROUND
11572	METHODS
11573	METHODS
11574	METHODS
11575	METHODS
11576	RESULTS
11577	RESULTS
11578	RESULTS
11579	RESULTS
11580	RESULTS
11581	RESULTS
11582	CONCLUSIONS
11583	CONCLUSIONS
11584	CONCLUSIONS
11585	OBJECTIVE
11586	METHODS
11587	METHODS
11588	METHODS
11589	METHODS
11590	RESULTS
11591	RESULTS
11592	CONCLUSIONS
11593	CONCLUSIONS
11594	CONCLUSIONS
11595	OBJECTIVE
11596	METHODS
11597	METHODS
11598	METHODS
11599	OBJECTIVE
11600	RESULTS
11601	RESULTS
11602	RESULTS
11603	RESULTS
11604	CONCLUSIONS
11605	BACKGROUND
11606	BACKGROUND
11607	BACKGROUND
11608	METHODS
11609	METHODS
11610	METHODS
11611	RESULTS
11612	RESULTS
11613	RESULTS
11614	RESULTS
11615	BACKGROUND
11616	BACKGROUND
11617	BACKGROUND
11618	METHODS
11619	METHODS
11620	METHODS
11621	METHODS
11622	METHODS
11623	METHODS
11624	RESULTS
11625	RESULTS
11626	RESULTS
11627	CONCLUSIONS
11628	BACKGROUND
11629	BACKGROUND
11630	BACKGROUND
11631	METHODS
11632	METHODS
11633	METHODS
11634	METHODS
11635	METHODS
11636	RESULTS
11637	RESULTS
11638	RESULTS
11639	RESULTS
11640	RESULTS
11641	CONCLUSIONS
11642	BACKGROUND
11643	METHODS
11644	METHODS
11645	METHODS
11646	METHODS
11647	METHODS
11648	RESULTS
11649	RESULTS
11650	RESULTS
11651	RESULTS
11652	CONCLUSIONS
11653	BACKGROUND
11654	OBJECTIVE
11655	METHODS
11656	METHODS
11657	METHODS
11658	METHODS
11659	RESULTS
11660	RESULTS
11661	RESULTS
11662	RESULTS
11663	RESULTS
11664	RESULTS
11665	RESULTS
11666	RESULTS
11667	CONCLUSIONS
11668	CONCLUSIONS
11669	OBJECTIVE
11670	METHODS
11671	METHODS
11672	METHODS
11673	METHODS
11674	RESULTS
11675	RESULTS
11676	RESULTS
11677	RESULTS
11678	RESULTS
11679	RESULTS
11680	RESULTS
11681	RESULTS
11682	RESULTS
11683	RESULTS
11684	CONCLUSIONS
11685	CONCLUSIONS
11686	OBJECTIVE
11687	RESULTS
11688	CONCLUSIONS
11689	OBJECTIVE
11690	OBJECTIVE
11691	METHODS
11692	METHODS
11693	RESULTS
11694	RESULTS
11695	RESULTS
11696	RESULTS
11697	CONCLUSIONS
11698	OBJECTIVE
11699	METHODS
11700	METHODS
11701	METHODS
11702	METHODS
11703	METHODS
11704	RESULTS
11705	RESULTS
11706	RESULTS
11707	RESULTS
11708	CONCLUSIONS
11709	BACKGROUND
11710	BACKGROUND
11711	OBJECTIVE
11712	METHODS
11713	METHODS
11714	CONCLUSIONS
11715	CONCLUSIONS
11716	RESULTS
11717	CONCLUSIONS
11718	OBJECTIVE
11719	METHODS
11720	METHODS
11721	METHODS
11722	METHODS
11723	RESULTS
11724	RESULTS
11725	RESULTS
11726	RESULTS
11727	CONCLUSIONS
11728	CONCLUSIONS
11729	BACKGROUND
11730	BACKGROUND
11731	BACKGROUND
11732	CONCLUSIONS
11733	BACKGROUND
11734	METHODS
11735	METHODS
11736	METHODS
11737	METHODS
11738	METHODS
11739	RESULTS
11740	RESULTS
11741	CONCLUSIONS
11742	CONCLUSIONS
11743	BACKGROUND
11744	OBJECTIVE
11745	METHODS
11746	METHODS
11747	METHODS
11748	METHODS
11749	METHODS
11750	METHODS
11751	METHODS
11752	RESULTS
11753	RESULTS
11754	RESULTS
11755	METHODS
11756	RESULTS
11757	RESULTS
11758	RESULTS
11759	CONCLUSIONS
11760	OBJECTIVE
11761	OBJECTIVE
11762	METHODS
11763	METHODS
11764	METHODS
11765	METHODS
11766	RESULTS
11767	RESULTS
11768	RESULTS
11769	RESULTS
11770	CONCLUSIONS
11771	CONCLUSIONS
11772	OBJECTIVE
11773	METHODS
11774	METHODS
11775	METHODS
11776	RESULTS
11777	RESULTS
11778	RESULTS
11779	RESULTS
11780	CONCLUSIONS
11781	OBJECTIVE
11782	METHODS
11783	METHODS
11784	METHODS
11785	METHODS
11786	METHODS
11787	RESULTS
11788	RESULTS
11789	CONCLUSIONS
11790	BACKGROUND
11791	OBJECTIVE
11792	METHODS
11793	METHODS
11794	RESULTS
11795	RESULTS
11796	METHODS
11797	RESULTS
11798	RESULTS
11799	RESULTS
11800	CONCLUSIONS
11801	BACKGROUND
11802	CONCLUSIONS
11803	CONCLUSIONS
11804	BACKGROUND
11805	BACKGROUND
11806	METHODS
11807	BACKGROUND
11808	METHODS
11809	METHODS
11810	METHODS
11811	METHODS
11812	METHODS
11813	METHODS
11814	METHODS
11815	BACKGROUND
11816	CONCLUSIONS
11817	BACKGROUND
11818	BACKGROUND
11819	OBJECTIVE
11820	METHODS
11821	METHODS
11822	RESULTS
11823	RESULTS
11824	RESULTS
11825	CONCLUSIONS
11826	CONCLUSIONS
11827	OBJECTIVE
11828	METHODS
11829	METHODS
11830	METHODS
11831	METHODS
11832	RESULTS
11833	RESULTS
11834	RESULTS
11835	CONCLUSIONS
11836	BACKGROUND
11837	METHODS
11838	BACKGROUND
11839	BACKGROUND
11840	CONCLUSIONS
11841	BACKGROUND
11842	BACKGROUND
11843	BACKGROUND
11844	METHODS
11845	METHODS
11846	METHODS
11847	METHODS
11848	METHODS
11849	METHODS
11850	METHODS
11851	METHODS
11852	METHODS
11853	CONCLUSIONS
11854	BACKGROUND
11855	OBJECTIVE
11856	METHODS
11857	METHODS
11858	METHODS
11859	METHODS
11860	RESULTS
11861	RESULTS
11862	RESULTS
11863	RESULTS
11864	CONCLUSIONS
11865	CONCLUSIONS
11866	OBJECTIVE
11867	METHODS
11868	METHODS
11869	METHODS
11870	METHODS
11871	RESULTS
11872	RESULTS
11873	RESULTS
11874	RESULTS
11875	RESULTS
11876	RESULTS
11877	RESULTS
11878	OBJECTIVE
11879	METHODS
11880	METHODS
11881	METHODS
11882	METHODS
11883	METHODS
11884	METHODS
11885	METHODS
11886	METHODS
11887	RESULTS
11888	RESULTS
11889	RESULTS
11890	CONCLUSIONS
11891	CONCLUSIONS
11892	RESULTS
11893	OBJECTIVE
11894	METHODS
11895	BACKGROUND
11896	BACKGROUND
11897	METHODS
11898	RESULTS
11899	RESULTS
11900	RESULTS
11901	OBJECTIVE
11902	METHODS
11903	METHODS
11904	RESULTS
11905	RESULTS
11906	RESULTS
11907	RESULTS
11908	RESULTS
11909	RESULTS
11910	RESULTS
11911	RESULTS
11912	CONCLUSIONS
11913	OBJECTIVE
11914	METHODS
11915	METHODS
11916	METHODS
11917	METHODS
11918	RESULTS
11919	RESULTS
11920	RESULTS
11921	RESULTS
11922	RESULTS
11923	RESULTS
11924	CONCLUSIONS
11925	METHODS
11926	CONCLUSIONS
11927	BACKGROUND
11928	BACKGROUND
11929	OBJECTIVE
11930	METHODS
11931	METHODS
11932	METHODS
11933	METHODS
11934	METHODS
11935	RESULTS
11936	RESULTS
11937	RESULTS
11938	RESULTS
11939	RESULTS
11940	RESULTS
11941	RESULTS
11942	CONCLUSIONS
11943	OBJECTIVE
11944	OBJECTIVE
11945	METHODS
11946	METHODS
11947	METHODS
11948	METHODS
11949	RESULTS
11950	RESULTS
11951	CONCLUSIONS
11952	CONCLUSIONS
11953	OBJECTIVE
11954	METHODS
11955	METHODS
11956	RESULTS
11957	RESULTS
11958	RESULTS
11959	CONCLUSIONS
11960	OBJECTIVE
11961	METHODS
11962	METHODS
11963	METHODS
11964	METHODS
11965	RESULTS
11966	RESULTS
11967	CONCLUSIONS
11968	OBJECTIVE
11969	METHODS
11970	METHODS
11971	METHODS
11972	METHODS
11973	METHODS
11974	METHODS
11975	RESULTS
11976	RESULTS
11977	RESULTS
11978	CONCLUSIONS
11979	BACKGROUND
11980	OBJECTIVE
11981	OBJECTIVE
11982	METHODS
11983	METHODS
11984	METHODS
11985	METHODS
11986	RESULTS
11987	RESULTS
11988	RESULTS
11989	CONCLUSIONS
11990	CONCLUSIONS
11991	CONCLUSIONS
11992	OBJECTIVE
11993	METHODS
11994	METHODS
11995	METHODS
11996	RESULTS
11997	RESULTS
11998	RESULTS
11999	RESULTS
12000	RESULTS
12001	CONCLUSIONS
12002	CONCLUSIONS
12003	OBJECTIVE
12004	OBJECTIVE
12005	METHODS
12006	METHODS
12007	METHODS
12008	METHODS
12009	METHODS
12010	RESULTS
12011	RESULTS
12012	RESULTS
12013	RESULTS
12014	RESULTS
12015	RESULTS
12016	RESULTS
12017	CONCLUSIONS
12018	BACKGROUND
12019	METHODS
12020	METHODS
12021	METHODS
12022	METHODS
12023	RESULTS
12024	RESULTS
12025	RESULTS
12026	CONCLUSIONS
12027	BACKGROUND
12028	BACKGROUND
12029	BACKGROUND
12030	BACKGROUND
12031	OBJECTIVE
12032	METHODS
12033	METHODS
12034	METHODS
12035	RESULTS
12036	RESULTS
12037	RESULTS
12038	CONCLUSIONS
12039	OBJECTIVE
12040	METHODS
12041	METHODS
12042	METHODS
12043	RESULTS
12044	RESULTS
12045	RESULTS
12046	RESULTS
12047	RESULTS
12048	CONCLUSIONS
12049	CONCLUSIONS
12050	OBJECTIVE
12051	METHODS
12052	METHODS
12053	CONCLUSIONS
12054	RESULTS
12055	CONCLUSIONS
12056	BACKGROUND
12057	BACKGROUND
12058	BACKGROUND
12059	OBJECTIVE
12060	METHODS
12061	METHODS
12062	METHODS
12063	METHODS
12064	METHODS
12065	METHODS
12066	METHODS
12067	METHODS
12068	RESULTS
12069	RESULTS
12070	RESULTS
12071	RESULTS
12072	CONCLUSIONS
12073	CONCLUSIONS
12074	BACKGROUND
12075	METHODS
12076	METHODS
12077	METHODS
12078	METHODS
12079	RESULTS
12080	RESULTS
12081	RESULTS
12082	RESULTS
12083	BACKGROUND
12084	CONCLUSIONS
12085	BACKGROUND
12086	OBJECTIVE
12087	OBJECTIVE
12088	RESULTS
12089	RESULTS
12090	RESULTS
12091	RESULTS
12092	RESULTS
12093	CONCLUSIONS
12094	OBJECTIVE
12095	METHODS
12096	METHODS
12097	METHODS
12098	METHODS
12099	METHODS
12100	RESULTS
12101	RESULTS
12102	RESULTS
12103	RESULTS
12104	CONCLUSIONS
12105	CONCLUSIONS
12106	BACKGROUND
12107	BACKGROUND
12108	RESULTS
12109	RESULTS
12110	RESULTS
12111	RESULTS
12112	RESULTS
12113	RESULTS
12114	CONCLUSIONS
12115	CONCLUSIONS
12116	OBJECTIVE
12117	METHODS
12118	METHODS
12119	METHODS
12120	METHODS
12121	RESULTS
12122	RESULTS
12123	RESULTS
12124	CONCLUSIONS
12125	OBJECTIVE
12126	METHODS
12127	RESULTS
12128	RESULTS
12129	RESULTS
12130	RESULTS
12131	CONCLUSIONS
12132	BACKGROUND
12133	BACKGROUND
12134	BACKGROUND
12135	OBJECTIVE
12136	METHODS
12137	METHODS
12138	METHODS
12139	RESULTS
12140	RESULTS
12141	RESULTS
12142	CONCLUSIONS
12143	BACKGROUND
12144	BACKGROUND
12145	METHODS
12146	METHODS
12147	METHODS
12148	METHODS
12149	METHODS
12150	METHODS
12151	RESULTS
12152	RESULTS
12153	RESULTS
12154	CONCLUSIONS
12155	CONCLUSIONS
12156	OBJECTIVE
12157	METHODS
12158	METHODS
12159	METHODS
12160	METHODS
12161	METHODS
12162	METHODS
12163	METHODS
12164	RESULTS
12165	RESULTS
12166	RESULTS
12167	RESULTS
12168	CONCLUSIONS
12169	CONCLUSIONS
12170	OBJECTIVE
12171	METHODS
12172	METHODS
12173	RESULTS
12174	METHODS
12175	RESULTS
12176	RESULTS
12177	RESULTS
12178	CONCLUSIONS
12179	CONCLUSIONS
12180	CONCLUSIONS
12181	CONCLUSIONS
12182	OBJECTIVE
12183	METHODS
12184	METHODS
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12186	METHODS
12187	RESULTS
12188	RESULTS
12189	RESULTS
12190	RESULTS
12191	CONCLUSIONS
12192	OBJECTIVE
12193	METHODS
12194	METHODS
12195	RESULTS
12196	RESULTS
12197	CONCLUSIONS
12198	BACKGROUND
12199	BACKGROUND
12200	METHODS
12201	METHODS
12202	METHODS
12203	RESULTS
12204	RESULTS
12205	RESULTS
12206	RESULTS
12207	BACKGROUND
12208	CONCLUSIONS
12209	BACKGROUND
12210	BACKGROUND
12211	BACKGROUND
12212	BACKGROUND
12213	BACKGROUND
12214	RESULTS
12215	RESULTS
12216	CONCLUSIONS
12217	BACKGROUND
12218	BACKGROUND
12219	BACKGROUND
12220	OBJECTIVE
12221	METHODS
12222	METHODS
12223	METHODS
12224	RESULTS
12225	RESULTS
12226	CONCLUSIONS
12227	BACKGROUND
12228	BACKGROUND
12229	METHODS
12230	RESULTS
12231	RESULTS
12232	RESULTS
12233	RESULTS
12234	CONCLUSIONS
12235	CONCLUSIONS
12236	OBJECTIVE
12237	METHODS
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12241	RESULTS
12242	RESULTS
12243	CONCLUSIONS
12244	CONCLUSIONS
12245	OBJECTIVE
12246	RESULTS
12247	OBJECTIVE
12248	METHODS
12249	METHODS
12250	RESULTS
12251	RESULTS
12252	RESULTS
12253	CONCLUSIONS
12254	OBJECTIVE
12255	METHODS
12256	METHODS
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12260	METHODS
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12262	RESULTS
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12267	RESULTS
12268	CONCLUSIONS
12269	RESULTS
12270	CONCLUSIONS
12271	CONCLUSIONS
12272	CONCLUSIONS
12273	BACKGROUND
12274	OBJECTIVE
12275	METHODS
12276	METHODS
12277	RESULTS
12278	RESULTS
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12280	RESULTS
12281	RESULTS
12282	CONCLUSIONS
12283	BACKGROUND
12284	BACKGROUND
12285	OBJECTIVE
12286	METHODS
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12290	BACKGROUND
12291	CONCLUSIONS
12292	OBJECTIVE
12293	METHODS
12294	RESULTS
12295	RESULTS
12296	RESULTS
12297	RESULTS
12298	RESULTS
12299	RESULTS
12300	CONCLUSIONS
12301	BACKGROUND
12302	OBJECTIVE
12303	BACKGROUND
12304	METHODS
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12307	METHODS
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12309	RESULTS
12310	RESULTS
12311	RESULTS
12312	RESULTS
12313	RESULTS
12314	RESULTS
12315	BACKGROUND
12316	CONCLUSIONS
12317	CONCLUSIONS
12318	CONCLUSIONS
12319	OBJECTIVE
12320	METHODS
12321	METHODS
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12325	RESULTS
12326	RESULTS
12327	RESULTS
12328	CONCLUSIONS
12329	CONCLUSIONS
12330	OBJECTIVE
12331	OBJECTIVE
12332	METHODS
12333	METHODS
12334	METHODS
12335	RESULTS
12336	RESULTS
12337	RESULTS
12338	RESULTS
12339	CONCLUSIONS
12340	CONCLUSIONS
12341	BACKGROUND
12342	OBJECTIVE
12343	METHODS
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12345	METHODS
12346	METHODS
12347	RESULTS
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12350	RESULTS
12351	RESULTS
12352	RESULTS
12353	RESULTS
12354	CONCLUSIONS
12355	BACKGROUND
12356	BACKGROUND
12357	BACKGROUND
12358	METHODS
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12360	METHODS
12361	METHODS
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12364	RESULTS
12365	RESULTS
12366	RESULTS
12367	RESULTS
12368	RESULTS
12369	CONCLUSIONS
12370	BACKGROUND
12371	BACKGROUND
12372	OBJECTIVE
12373	METHODS
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12380	RESULTS
12381	RESULTS
12382	CONCLUSIONS
12383	OBJECTIVE
12384	METHODS
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12389	RESULTS
12390	RESULTS
12391	RESULTS
12392	RESULTS
12393	RESULTS
12394	RESULTS
12395	RESULTS
12396	RESULTS
12397	RESULTS
12398	RESULTS
12399	BACKGROUND
12400	RESULTS
12401	CONCLUSIONS
12402	CONCLUSIONS
12403	BACKGROUND
12404	BACKGROUND
12405	BACKGROUND
12406	BACKGROUND
12407	METHODS
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12409	METHODS
12410	METHODS
12411	METHODS
12412	RESULTS
12413	RESULTS
12414	RESULTS
12415	RESULTS
12416	RESULTS
12417	RESULTS
12418	CONCLUSIONS
12419	CONCLUSIONS
12420	BACKGROUND
12421	BACKGROUND
12422	BACKGROUND
12423	OBJECTIVE
12424	METHODS
12425	METHODS
12426	RESULTS
12427	RESULTS
12428	RESULTS
12429	CONCLUSIONS
12430	RESULTS
12431	CONCLUSIONS
12432	BACKGROUND
12433	BACKGROUND
12434	METHODS
12435	METHODS
12436	RESULTS
12437	RESULTS
12438	RESULTS
12439	RESULTS
12440	RESULTS
12441	RESULTS
12442	CONCLUSIONS
12443	CONCLUSIONS
12444	OBJECTIVE
12445	METHODS
12446	METHODS
12447	METHODS
12448	METHODS
12449	RESULTS
12450	RESULTS
12451	RESULTS
12452	RESULTS
12453	CONCLUSIONS
12454	CONCLUSIONS
12455	OBJECTIVE
12456	METHODS
12457	METHODS
12458	METHODS
12459	METHODS
12460	RESULTS
12461	RESULTS
12462	RESULTS
12463	RESULTS
12464	CONCLUSIONS
12465	BACKGROUND
12466	BACKGROUND
12467	OBJECTIVE
12468	OBJECTIVE
12469	METHODS
12470	METHODS
12471	METHODS
12472	RESULTS
12473	RESULTS
12474	CONCLUSIONS
12475	OBJECTIVE
12476	BACKGROUND
12477	METHODS
12478	METHODS
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12480	RESULTS
12481	RESULTS
12482	CONCLUSIONS
12483	BACKGROUND
12484	BACKGROUND
12485	OBJECTIVE
12486	METHODS
12487	METHODS
12488	METHODS
12489	METHODS
12490	CONCLUSIONS
12491	RESULTS
12492	CONCLUSIONS
12493	CONCLUSIONS
12494	RESULTS
12495	CONCLUSIONS
12496	CONCLUSIONS
12497	BACKGROUND
12498	BACKGROUND
12499	BACKGROUND
12500	METHODS
12501	METHODS
12502	METHODS
12503	METHODS
12504	METHODS
12505	RESULTS
12506	RESULTS
12507	BACKGROUND
12508	BACKGROUND
12509	BACKGROUND
12510	BACKGROUND
12511	BACKGROUND
12512	BACKGROUND
12513	BACKGROUND
12514	METHODS
12515	METHODS
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12518	METHODS
12519	METHODS
12520	METHODS
12521	RESULTS
12522	RESULTS
12523	RESULTS
12524	RESULTS
12525	RESULTS
12526	CONCLUSIONS
12527	RESULTS
12528	BACKGROUND
12529	BACKGROUND
12530	BACKGROUND
12531	BACKGROUND
12532	METHODS
12533	RESULTS
12534	RESULTS
12535	RESULTS
12536	RESULTS
12537	CONCLUSIONS
12538	CONCLUSIONS
12539	BACKGROUND
12540	OBJECTIVE
12541	OBJECTIVE
12542	METHODS
12543	METHODS
12544	METHODS
12545	RESULTS
12546	CONCLUSIONS
12547	CONCLUSIONS
12548	CONCLUSIONS
12549	CONCLUSIONS
12550	BACKGROUND
12551	METHODS
12552	METHODS
12553	METHODS
12554	RESULTS
12555	RESULTS
12556	RESULTS
12557	RESULTS
12558	RESULTS
12559	RESULTS
12560	CONCLUSIONS
12561	CONCLUSIONS
12562	BACKGROUND
12563	BACKGROUND
12564	METHODS
12565	METHODS
12566	METHODS
12567	METHODS
12568	BACKGROUND
12569	RESULTS
12570	RESULTS
12571	RESULTS
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12573	RESULTS
12574	RESULTS
12575	CONCLUSIONS
12576	CONCLUSIONS
12577	BACKGROUND
12578	BACKGROUND
12579	OBJECTIVE
12580	METHODS
12581	METHODS
12582	METHODS
12583	METHODS
12584	METHODS
12585	METHODS
12586	METHODS
12587	METHODS
12588	RESULTS
12589	CONCLUSIONS
12590	CONCLUSIONS
12591	BACKGROUND
12592	BACKGROUND
12593	METHODS
12594	METHODS
12595	METHODS
12596	RESULTS
12597	RESULTS
12598	CONCLUSIONS
12599	OBJECTIVE
12600	METHODS
12601	METHODS
12602	METHODS
12603	METHODS
12604	METHODS
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12606	METHODS
12607	RESULTS
12608	RESULTS
12609	CONCLUSIONS
12610	RESULTS
12611	CONCLUSIONS
12612	OBJECTIVE
12613	METHODS
12614	METHODS
12615	METHODS
12616	METHODS
12617	METHODS
12618	METHODS
12619	RESULTS
12620	RESULTS
12621	RESULTS
12622	RESULTS
12623	RESULTS
12624	CONCLUSIONS
12625	CONCLUSIONS
12626	CONCLUSIONS
12627	OBJECTIVE
12628	METHODS
12629	METHODS
12630	METHODS
12631	RESULTS
12632	RESULTS
12633	CONCLUSIONS
12634	BACKGROUND
12635	BACKGROUND
12636	BACKGROUND
12637	METHODS
12638	METHODS
12639	METHODS
12640	RESULTS
12641	RESULTS
12642	RESULTS
12643	RESULTS
12644	CONCLUSIONS
12645	CONCLUSIONS
12646	BACKGROUND
12647	METHODS
12648	METHODS
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12650	METHODS
12651	RESULTS
12652	RESULTS
12653	RESULTS
12654	RESULTS
12655	RESULTS
12656	METHODS
12657	BACKGROUND
12658	OBJECTIVE
12659	METHODS
12660	METHODS
12661	RESULTS
12662	RESULTS
12663	RESULTS
12664	RESULTS
12665	RESULTS
12666	RESULTS
12667	CONCLUSIONS
12668	CONCLUSIONS
12669	BACKGROUND
12670	METHODS
12671	METHODS
12672	METHODS
12673	METHODS
12674	METHODS
12675	RESULTS
12676	RESULTS
12677	RESULTS
12678	RESULTS
12679	RESULTS
12680	RESULTS
12681	RESULTS
12682	RESULTS
12683	RESULTS
12684	CONCLUSIONS
12685	CONCLUSIONS
12686	BACKGROUND
12687	OBJECTIVE
12688	METHODS
12689	METHODS
12690	METHODS
12691	RESULTS
12692	RESULTS
12693	RESULTS
12694	CONCLUSIONS
12695	OBJECTIVE
12696	METHODS
12697	METHODS
12698	METHODS
12699	METHODS
12700	RESULTS
12701	RESULTS
12702	RESULTS
12703	RESULTS
12704	RESULTS
12705	RESULTS
12706	BACKGROUND
12707	METHODS
12708	RESULTS
12709	METHODS
12710	METHODS
12711	RESULTS
12712	RESULTS
12713	METHODS
12714	RESULTS
12715	RESULTS
12716	RESULTS
12717	RESULTS
12718	RESULTS
12719	RESULTS
12720	RESULTS
12721	RESULTS
12722	RESULTS
12723	RESULTS
12724	RESULTS
12725	RESULTS
12726	RESULTS
12727	CONCLUSIONS
12728	BACKGROUND
12729	BACKGROUND
12730	METHODS
12731	METHODS
12732	METHODS
12733	METHODS
12734	METHODS
12735	RESULTS
12736	RESULTS
12737	RESULTS
12738	RESULTS
12739	RESULTS
12740	RESULTS
12741	BACKGROUND
12742	RESULTS
12743	OBJECTIVE
12744	METHODS
12745	METHODS
12746	METHODS
12747	RESULTS
12748	RESULTS
12749	RESULTS
12750	CONCLUSIONS
12751	BACKGROUND
12752	BACKGROUND
12753	OBJECTIVE
12754	METHODS
12755	RESULTS
12756	METHODS
12757	METHODS
12758	METHODS
12759	METHODS
12760	RESULTS
12761	RESULTS
12762	RESULTS
12763	RESULTS
12764	RESULTS
12765	RESULTS
12766	RESULTS
12767	RESULTS
12768	CONCLUSIONS
12769	CONCLUSIONS
12770	CONCLUSIONS
12771	BACKGROUND
12772	METHODS
12773	METHODS
12774	METHODS
12775	RESULTS
12776	RESULTS
12777	RESULTS
12778	RESULTS
12779	RESULTS
12780	RESULTS
12781	CONCLUSIONS
12782	BACKGROUND
12783	BACKGROUND
12784	METHODS
12785	METHODS
12786	RESULTS
12787	RESULTS
12788	RESULTS
12789	RESULTS
12790	RESULTS
12791	CONCLUSIONS
12792	OBJECTIVE
12793	METHODS
12794	METHODS
12795	METHODS
12796	RESULTS
12797	RESULTS
12798	RESULTS
12799	RESULTS
12800	RESULTS
12801	CONCLUSIONS
12802	CONCLUSIONS
12803	CONCLUSIONS
12804	OBJECTIVE
12805	METHODS
12806	METHODS
12807	METHODS
12808	METHODS
12809	METHODS
12810	METHODS
12811	METHODS
12812	METHODS
12813	METHODS
12814	RESULTS
12815	RESULTS
12816	RESULTS
12817	CONCLUSIONS
12818	CONCLUSIONS
12819	BACKGROUND
12820	BACKGROUND
12821	BACKGROUND
12822	METHODS
12823	METHODS
12824	METHODS
12825	METHODS
12826	METHODS
12827	RESULTS
12828	RESULTS
12829	RESULTS
12830	RESULTS
12831	RESULTS
12832	CONCLUSIONS
12833	CONCLUSIONS
12834	CONCLUSIONS
12835	BACKGROUND
12836	CONCLUSIONS
12837	BACKGROUND
12838	OBJECTIVE
12839	METHODS
12840	METHODS
12841	METHODS
12842	METHODS
12843	METHODS
12844	RESULTS
12845	RESULTS
12846	RESULTS
12847	RESULTS
12848	CONCLUSIONS
12849	OBJECTIVE
12850	METHODS
12851	METHODS
12852	RESULTS
12853	RESULTS
12854	RESULTS
12855	RESULTS
12856	RESULTS
12857	RESULTS
12858	RESULTS
12859	CONCLUSIONS
12860	CONCLUSIONS
12861	BACKGROUND
12862	OBJECTIVE
12863	METHODS
12864	METHODS
12865	RESULTS
12866	RESULTS
12867	RESULTS
12868	RESULTS
12869	RESULTS
12870	RESULTS
12871	RESULTS
12872	OBJECTIVE
12873	METHODS
12874	METHODS
12875	METHODS
12876	METHODS
12877	METHODS
12878	METHODS
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12880	RESULTS
12881	RESULTS
12882	CONCLUSIONS
12883	BACKGROUND
12884	BACKGROUND
12885	CONCLUSIONS
12886	BACKGROUND
12887	BACKGROUND
12888	BACKGROUND
12889	OBJECTIVE
12890	METHODS
12891	METHODS
12892	METHODS
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12894	METHODS
12895	RESULTS
12896	RESULTS
12897	RESULTS
12898	CONCLUSIONS
12899	CONCLUSIONS
12900	BACKGROUND
12901	OBJECTIVE
12902	METHODS
12903	METHODS
12904	METHODS
12905	METHODS
12906	METHODS
12907	METHODS
12908	RESULTS
12909	RESULTS
12910	CONCLUSIONS
12911	CONCLUSIONS
12912	BACKGROUND
12913	BACKGROUND
12914	METHODS
12915	METHODS
12916	RESULTS
12917	RESULTS
12918	RESULTS
12919	RESULTS
12920	RESULTS
12921	RESULTS
12922	CONCLUSIONS
12923	METHODS
12924	METHODS
12925	RESULTS
12926	RESULTS
12927	RESULTS
12928	RESULTS
12929	BACKGROUND
12930	BACKGROUND
12931	METHODS
12932	METHODS
12933	METHODS
12934	METHODS
12935	RESULTS
12936	RESULTS
12937	RESULTS
12938	RESULTS
12939	RESULTS
12940	CONCLUSIONS
12941	BACKGROUND
12942	BACKGROUND
12943	BACKGROUND
12944	CONCLUSIONS
12945	METHODS
12946	METHODS
12947	METHODS
12948	METHODS
12949	METHODS
12950	METHODS
12951	METHODS
12952	METHODS
12953	METHODS
12954	METHODS
12955	METHODS
12956	METHODS
12957	METHODS
12958	METHODS
12959	METHODS
12960	BACKGROUND
12961	CONCLUSIONS
12962	CONCLUSIONS
12963	BACKGROUND
12964	BACKGROUND
12965	OBJECTIVE
12966	OBJECTIVE
12967	METHODS
12968	METHODS
12969	RESULTS
12970	RESULTS
12971	RESULTS
12972	CONCLUSIONS
12973	CONCLUSIONS
12974	OBJECTIVE
12975	BACKGROUND
12976	METHODS
12977	METHODS
12978	METHODS
12979	METHODS
12980	METHODS
12981	RESULTS
12982	RESULTS
12983	RESULTS
12984	RESULTS
12985	CONCLUSIONS
12986	OBJECTIVE
12987	METHODS
12988	METHODS
12989	METHODS
12990	METHODS
12991	METHODS
12992	METHODS
12993	METHODS
12994	METHODS
12995	RESULTS
12996	RESULTS
12997	CONCLUSIONS
12998	OBJECTIVE
12999	METHODS
13000	METHODS
13001	RESULTS
13002	RESULTS
13003	CONCLUSIONS
13004	METHODS
13005	BACKGROUND
13006	BACKGROUND
13007	METHODS
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13010	METHODS
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13012	METHODS
13013	METHODS
13014	RESULTS
13015	RESULTS
13016	RESULTS
13017	RESULTS
13018	RESULTS
13019	CONCLUSIONS
13020	BACKGROUND
13021	BACKGROUND
13022	BACKGROUND
13023	BACKGROUND
13024	METHODS
13025	METHODS
13026	METHODS
13027	METHODS
13028	METHODS
13029	METHODS
13030	METHODS
13031	METHODS
13032	METHODS
13033	METHODS
13034	METHODS
13035	CONCLUSIONS
13036	CONCLUSIONS
13037	CONCLUSIONS
13038	BACKGROUND
13039	BACKGROUND
13040	OBJECTIVE
13041	METHODS
13042	METHODS
13043	METHODS
13044	METHODS
13045	RESULTS
13046	RESULTS
13047	RESULTS
13048	RESULTS
13049	RESULTS
13050	CONCLUSIONS
13051	BACKGROUND
13052	OBJECTIVE
13053	METHODS
13054	METHODS
13055	METHODS
13056	RESULTS
13057	RESULTS
13058	RESULTS
13059	CONCLUSIONS
13060	RESULTS
13061	RESULTS
13062	RESULTS
13063	RESULTS
13064	RESULTS
13065	OBJECTIVE
13066	METHODS
13067	METHODS
13068	METHODS
13069	METHODS
13070	RESULTS
13071	RESULTS
13072	RESULTS
13073	CONCLUSIONS
13074	METHODS
13075	OBJECTIVE
13076	OBJECTIVE
13077	METHODS
13078	METHODS
13079	METHODS
13080	METHODS
13081	METHODS
13082	RESULTS
13083	CONCLUSIONS
13084	CONCLUSIONS
13085	BACKGROUND
13086	BACKGROUND
13087	RESULTS
13088	RESULTS
13089	METHODS
13090	RESULTS
13091	RESULTS
13092	RESULTS
13093	RESULTS
13094	CONCLUSIONS
13095	RESULTS
13096	CONCLUSIONS
13097	BACKGROUND
13098	BACKGROUND
13099	METHODS
13100	BACKGROUND
13101	OBJECTIVE
13102	METHODS
13103	METHODS
13104	METHODS
13105	RESULTS
13106	RESULTS
13107	RESULTS
13108	CONCLUSIONS
13109	CONCLUSIONS
13110	CONCLUSIONS
13111	CONCLUSIONS
13112	OBJECTIVE
13113	METHODS
13114	METHODS
13115	RESULTS
13116	RESULTS
13117	CONCLUSIONS
13118	BACKGROUND
13119	OBJECTIVE
13120	METHODS
13121	METHODS
13122	RESULTS
13123	RESULTS
13124	RESULTS
13125	RESULTS
13126	RESULTS
13127	CONCLUSIONS
13128	OBJECTIVE
13129	OBJECTIVE
13130	METHODS
13131	METHODS
13132	METHODS
13133	METHODS
13134	RESULTS
13135	RESULTS
13136	RESULTS
13137	CONCLUSIONS
13138	OBJECTIVE
13139	METHODS
13140	METHODS
13141	METHODS
13142	METHODS
13143	METHODS
13144	METHODS
13145	RESULTS
13146	RESULTS
13147	RESULTS
13148	CONCLUSIONS
13149	OBJECTIVE
13150	METHODS
13151	METHODS
13152	RESULTS
13153	RESULTS
13154	RESULTS
13155	RESULTS
13156	RESULTS
13157	CONCLUSIONS
13158	CONCLUSIONS
13159	CONCLUSIONS
13160	CONCLUSIONS
13161	OBJECTIVE
13162	METHODS
13163	METHODS
13164	RESULTS
13165	RESULTS
13166	RESULTS
13167	RESULTS
13168	CONCLUSIONS
13169	OBJECTIVE
13170	OBJECTIVE
13171	METHODS
13172	METHODS
13173	RESULTS
13174	RESULTS
13175	RESULTS
13176	RESULTS
13177	CONCLUSIONS
13178	OBJECTIVE
13179	RESULTS
13180	METHODS
13181	METHODS
13182	RESULTS
13183	RESULTS
13184	RESULTS
13185	RESULTS
13186	RESULTS
13187	CONCLUSIONS
13188	BACKGROUND
13189	BACKGROUND
13190	METHODS
13191	RESULTS
13192	METHODS
13193	RESULTS
13194	RESULTS
13195	RESULTS
13196	RESULTS
13197	CONCLUSIONS
13198	CONCLUSIONS
13199	BACKGROUND
13200	OBJECTIVE
13201	RESULTS
13202	OBJECTIVE
13203	METHODS
13204	METHODS
13205	RESULTS
13206	RESULTS
13207	BACKGROUND
13208	CONCLUSIONS
13209	BACKGROUND
13210	METHODS
13211	METHODS
13212	METHODS
13213	METHODS
13214	RESULTS
13215	RESULTS
13216	RESULTS
13217	CONCLUSIONS
13218	CONCLUSIONS
13219	METHODS
13220	METHODS
13221	METHODS
13222	RESULTS
13223	RESULTS
13224	RESULTS
13225	OBJECTIVE
13226	BACKGROUND
13227	OBJECTIVE
13228	METHODS
13229	METHODS
13230	METHODS
13231	METHODS
13232	RESULTS
13233	RESULTS
13234	RESULTS
13235	RESULTS
13236	CONCLUSIONS
13237	CONCLUSIONS
13238	CONCLUSIONS
13239	CONCLUSIONS
13240	OBJECTIVE
13241	METHODS
13242	METHODS
13243	METHODS
13244	METHODS
13245	RESULTS
13246	RESULTS
13247	RESULTS
13248	CONCLUSIONS
13249	OBJECTIVE
13250	METHODS
13251	METHODS
13252	METHODS
13253	METHODS
13254	METHODS
13255	RESULTS
13256	RESULTS
13257	RESULTS
13258	RESULTS
13259	CONCLUSIONS
13260	BACKGROUND
13261	BACKGROUND
13262	METHODS
13263	METHODS
13264	METHODS
13265	METHODS
13266	RESULTS
13267	RESULTS
13268	CONCLUSIONS
13269	OBJECTIVE
13270	METHODS
13271	METHODS
13272	METHODS
13273	METHODS
13274	METHODS
13275	RESULTS
13276	RESULTS
13277	RESULTS
13278	RESULTS
13279	CONCLUSIONS
13280	BACKGROUND
13281	BACKGROUND
13282	BACKGROUND
13283	OBJECTIVE
13284	METHODS
13285	METHODS
13286	METHODS
13287	METHODS
13288	RESULTS
13289	RESULTS
13290	CONCLUSIONS
13291	CONCLUSIONS
13292	BACKGROUND
13293	METHODS
13294	METHODS
13295	RESULTS
13296	RESULTS
13297	RESULTS
13298	RESULTS
13299	RESULTS
13300	RESULTS
13301	RESULTS
13302	RESULTS
13303	OBJECTIVE
13304	METHODS
13305	METHODS
13306	METHODS
13307	METHODS
13308	METHODS
13309	RESULTS
13310	RESULTS
13311	RESULTS
13312	RESULTS
13313	RESULTS
13314	CONCLUSIONS
13315	RESULTS
13316	OBJECTIVE
13317	METHODS
13318	METHODS
13319	METHODS
13320	METHODS
13321	METHODS
13322	RESULTS
13323	RESULTS
13324	RESULTS
13325	RESULTS
13326	CONCLUSIONS
13327	BACKGROUND
13328	BACKGROUND
13329	METHODS
13330	METHODS
13331	METHODS
13332	RESULTS
13333	RESULTS
13334	RESULTS
13335	RESULTS
13336	RESULTS
13337	RESULTS
13338	CONCLUSIONS
13339	CONCLUSIONS
13340	BACKGROUND
13341	CONCLUSIONS
13342	OBJECTIVE
13343	METHODS
13344	METHODS
13345	METHODS
13346	RESULTS
13347	METHODS
13348	METHODS
13349	RESULTS
13350	CONCLUSIONS
13351	BACKGROUND
13352	BACKGROUND
13353	BACKGROUND
13354	BACKGROUND
13355	OBJECTIVE
13356	METHODS
13357	METHODS
13358	METHODS
13359	METHODS
13360	METHODS
13361	RESULTS
13362	CONCLUSIONS
13363	CONCLUSIONS
13364	BACKGROUND
13365	BACKGROUND
13366	BACKGROUND
13367	BACKGROUND
13368	METHODS
13369	METHODS
13370	METHODS
13371	METHODS
13372	METHODS
13373	CONCLUSIONS
13374	BACKGROUND
13375	OBJECTIVE
13376	OBJECTIVE
13377	METHODS
13378	METHODS
13379	METHODS
13380	RESULTS
13381	RESULTS
13382	RESULTS
13383	CONCLUSIONS
13384	CONCLUSIONS
13385	OBJECTIVE
13386	METHODS
13387	METHODS
13388	RESULTS
13389	RESULTS
13390	RESULTS
13391	CONCLUSIONS
13392	OBJECTIVE
13393	METHODS
13394	METHODS
13395	METHODS
13396	METHODS
13397	RESULTS
13398	RESULTS
13399	RESULTS
13400	RESULTS
13401	CONCLUSIONS
13402	OBJECTIVE
13403	BACKGROUND
13404	BACKGROUND
13405	BACKGROUND
13406	OBJECTIVE
13407	METHODS
13408	METHODS
13409	METHODS
13410	METHODS
13411	CONCLUSIONS
13412	CONCLUSIONS
13413	CONCLUSIONS
13414	OBJECTIVE
13415	METHODS
13416	METHODS
13417	METHODS
13418	METHODS
13419	METHODS
13420	RESULTS
13421	METHODS
13422	RESULTS
13423	RESULTS
13424	RESULTS
13425	CONCLUSIONS
13426	OBJECTIVE
13427	METHODS
13428	METHODS
13429	METHODS
13430	METHODS
13431	RESULTS
13432	RESULTS
13433	RESULTS
13434	RESULTS
13435	CONCLUSIONS
13436	CONCLUSIONS
13437	BACKGROUND
13438	BACKGROUND
13439	OBJECTIVE
13440	BACKGROUND
13441	METHODS
13442	METHODS
13443	METHODS
13444	RESULTS
13445	RESULTS
13446	CONCLUSIONS
13447	BACKGROUND
13448	BACKGROUND
13449	METHODS
13450	METHODS
13451	METHODS
13452	RESULTS
13453	RESULTS
13454	CONCLUSIONS
13455	RESULTS
13456	CONCLUSIONS
13457	BACKGROUND
13458	BACKGROUND
13459	OBJECTIVE
13460	METHODS
13461	METHODS
13462	METHODS
13463	METHODS
13464	RESULTS
13465	RESULTS
13466	CONCLUSIONS
13467	CONCLUSIONS
13468	OBJECTIVE
13469	METHODS
13470	METHODS
13471	METHODS
13472	METHODS
13473	RESULTS
13474	METHODS
13475	METHODS
13476	METHODS
13477	RESULTS
13478	RESULTS
13479	CONCLUSIONS
13480	BACKGROUND
13481	BACKGROUND
13482	METHODS
13483	METHODS
13484	METHODS
13485	OBJECTIVE
13486	RESULTS
13487	RESULTS
13488	RESULTS
13489	RESULTS
13490	CONCLUSIONS
13491	BACKGROUND
13492	OBJECTIVE
13493	METHODS
13494	RESULTS
13495	RESULTS
13496	RESULTS
13497	RESULTS
13498	RESULTS
13499	RESULTS
13500	METHODS
13501	RESULTS
13502	RESULTS
13503	CONCLUSIONS
13504	BACKGROUND
13505	BACKGROUND
13506	METHODS
13507	METHODS
13508	METHODS
13509	RESULTS
13510	RESULTS
13511	RESULTS
13512	RESULTS
13513	CONCLUSIONS
13514	CONCLUSIONS
13515	OBJECTIVE
13516	METHODS
13517	OBJECTIVE
13518	METHODS
13519	METHODS
13520	METHODS
13521	METHODS
13522	METHODS
13523	METHODS
13524	RESULTS
13525	RESULTS
13526	RESULTS
13527	CONCLUSIONS
13528	OBJECTIVE
13529	OBJECTIVE
13530	METHODS
13531	METHODS
13532	METHODS
13533	METHODS
13534	RESULTS
13535	RESULTS
13536	CONCLUSIONS
13537	CONCLUSIONS
13538	RESULTS
13539	RESULTS
13540	CONCLUSIONS
13541	BACKGROUND
13542	OBJECTIVE
13543	METHODS
13544	METHODS
13545	METHODS
13546	RESULTS
13547	RESULTS
13548	RESULTS
13549	RESULTS
13550	RESULTS
13551	RESULTS
13552	RESULTS
13553	CONCLUSIONS
13554	CONCLUSIONS
13555	CONCLUSIONS
13556	CONCLUSIONS
13557	OBJECTIVE
13558	METHODS
13559	METHODS
13560	METHODS
13561	METHODS
13562	METHODS
13563	METHODS
13564	METHODS
13565	METHODS
13566	METHODS
13567	RESULTS
13568	RESULTS
13569	RESULTS
13570	RESULTS
13571	CONCLUSIONS
13572	BACKGROUND
13573	OBJECTIVE
13574	RESULTS
13575	METHODS
13576	RESULTS
13577	RESULTS
13578	RESULTS
13579	RESULTS
13580	RESULTS
13581	RESULTS
13582	CONCLUSIONS
13583	BACKGROUND
13584	OBJECTIVE
13585	METHODS
13586	METHODS
13587	METHODS
13588	METHODS
13589	METHODS
13590	METHODS
13591	METHODS
13592	METHODS
13593	RESULTS
13594	RESULTS
13595	RESULTS
13596	RESULTS
13597	CONCLUSIONS
13598	BACKGROUND
13599	BACKGROUND
13600	OBJECTIVE
13601	METHODS
13602	METHODS
13603	RESULTS
13604	RESULTS
13605	RESULTS
13606	CONCLUSIONS
13607	OBJECTIVE
13608	METHODS
13609	METHODS
13610	METHODS
13611	METHODS
13612	METHODS
13613	RESULTS
13614	RESULTS
13615	RESULTS
13616	RESULTS
13617	RESULTS
13618	CONCLUSIONS
13619	BACKGROUND
13620	OBJECTIVE
13621	METHODS
13622	METHODS
13623	RESULTS
13624	CONCLUSIONS
13625	BACKGROUND
13626	BACKGROUND
13627	OBJECTIVE
13628	METHODS
13629	METHODS
13630	RESULTS
13631	RESULTS
13632	CONCLUSIONS
13633	OBJECTIVE
13634	METHODS
13635	METHODS
13636	METHODS
13637	METHODS
13638	METHODS
13639	METHODS
13640	RESULTS
13641	RESULTS
13642	RESULTS
13643	RESULTS
13644	RESULTS
13645	RESULTS
13646	RESULTS
13647	RESULTS
13648	RESULTS
13649	RESULTS
13650	CONCLUSIONS
13651	BACKGROUND
13652	OBJECTIVE
13653	METHODS
13654	METHODS
13655	METHODS
13656	METHODS
13657	RESULTS
13658	RESULTS
13659	RESULTS
13660	RESULTS
13661	RESULTS
13662	RESULTS
13663	CONCLUSIONS
13664	CONCLUSIONS
13665	OBJECTIVE
13666	OBJECTIVE
13667	METHODS
13668	METHODS
13669	METHODS
13670	METHODS
13671	METHODS
13672	METHODS
13673	METHODS
13674	RESULTS
13675	RESULTS
13676	RESULTS
13677	RESULTS
13678	RESULTS
13679	RESULTS
13680	BACKGROUND
13681	OBJECTIVE
13682	CONCLUSIONS
13683	OBJECTIVE
13684	METHODS
13685	METHODS
13686	METHODS
13687	RESULTS
13688	RESULTS
13689	METHODS
13690	RESULTS
13691	RESULTS
13692	CONCLUSIONS
13693	OBJECTIVE
13694	METHODS
13695	RESULTS
13696	RESULTS
13697	RESULTS
13698	RESULTS
13699	CONCLUSIONS
13700	BACKGROUND
13701	OBJECTIVE
13702	METHODS
13703	METHODS
13704	RESULTS
13705	RESULTS
13706	RESULTS
13707	RESULTS
13708	CONCLUSIONS
13709	CONCLUSIONS
13710	OBJECTIVE
13711	METHODS
13712	METHODS
13713	METHODS
13714	METHODS
13715	RESULTS
13716	RESULTS
13717	RESULTS
13718	RESULTS
13719	RESULTS
13720	CONCLUSIONS
13721	OBJECTIVE
13722	METHODS
13723	RESULTS
13724	METHODS
13725	RESULTS
13726	RESULTS
13727	RESULTS
13728	RESULTS
13729	BACKGROUND
13730	BACKGROUND
13731	BACKGROUND
13732	BACKGROUND
13733	METHODS
13734	METHODS
13735	METHODS
13736	RESULTS
13737	CONCLUSIONS
13738	CONCLUSIONS
13739	OBJECTIVE
13740	METHODS
13741	METHODS
13742	METHODS
13743	METHODS
13744	METHODS
13745	METHODS
13746	RESULTS
13747	RESULTS
13748	RESULTS
13749	CONCLUSIONS
13750	CONCLUSIONS
13751	RESULTS
13752	CONCLUSIONS
13753	BACKGROUND
13754	BACKGROUND
13755	OBJECTIVE
13756	METHODS
13757	METHODS
13758	METHODS
13759	RESULTS
13760	RESULTS
13761	RESULTS
13762	RESULTS
13763	CONCLUSIONS
13764	CONCLUSIONS
13765	OBJECTIVE
13766	RESULTS
13767	RESULTS
13768	RESULTS
13769	RESULTS
13770	RESULTS
13771	RESULTS
13772	RESULTS
13773	RESULTS
13774	RESULTS
13775	BACKGROUND
13776	OBJECTIVE
13777	METHODS
13778	METHODS
13779	METHODS
13780	RESULTS
13781	RESULTS
13782	RESULTS
13783	RESULTS
13784	RESULTS
13785	RESULTS
13786	CONCLUSIONS
13787	BACKGROUND
13788	BACKGROUND
13789	METHODS
13790	METHODS
13791	METHODS
13792	RESULTS
13793	RESULTS
13794	RESULTS
13795	RESULTS
13796	RESULTS
13797	RESULTS
13798	RESULTS
13799	CONCLUSIONS
13800	OBJECTIVE
13801	METHODS
13802	METHODS
13803	METHODS
13804	METHODS
13805	METHODS
13806	RESULTS
13807	CONCLUSIONS
13808	CONCLUSIONS
13809	OBJECTIVE
13810	METHODS
13811	METHODS
13812	METHODS
13813	METHODS
13814	METHODS
13815	METHODS
13816	METHODS
13817	METHODS
13818	METHODS
13819	RESULTS
13820	RESULTS
13821	CONCLUSIONS
13822	BACKGROUND
13823	CONCLUSIONS
13824	OBJECTIVE
13825	METHODS
13826	METHODS
13827	METHODS
13828	CONCLUSIONS
13829	RESULTS
13830	CONCLUSIONS
13831	OBJECTIVE
13832	METHODS
13833	METHODS
13834	METHODS
13835	METHODS
13836	METHODS
13837	METHODS
13838	RESULTS
13839	RESULTS
13840	RESULTS
13841	RESULTS
13842	CONCLUSIONS
13843	METHODS
13844	METHODS
13845	RESULTS
13846	RESULTS
13847	RESULTS
13848	RESULTS
13849	RESULTS
13850	CONCLUSIONS
13851	OBJECTIVE
13852	METHODS
13853	METHODS
13854	METHODS
13855	RESULTS
13856	RESULTS
13857	RESULTS
13858	CONCLUSIONS
13859	CONCLUSIONS
13860	OBJECTIVE
13861	METHODS
13862	METHODS
13863	METHODS
13864	RESULTS
13865	RESULTS
13866	CONCLUSIONS
13867	BACKGROUND
13868	METHODS
13869	METHODS
13870	METHODS
13871	RESULTS
13872	RESULTS
13873	CONCLUSIONS
13874	BACKGROUND
13875	BACKGROUND
13876	BACKGROUND
13877	METHODS
13878	METHODS
13879	RESULTS
13880	CONCLUSIONS
13881	BACKGROUND
13882	OBJECTIVE
13883	METHODS
13884	METHODS
13885	METHODS
13886	METHODS
13887	RESULTS
13888	RESULTS
13889	RESULTS
13890	RESULTS
13891	CONCLUSIONS
13892	CONCLUSIONS
13893	BACKGROUND
13894	BACKGROUND
13895	BACKGROUND
13896	METHODS
13897	METHODS
13898	METHODS
13899	RESULTS
13900	RESULTS
13901	RESULTS
13902	RESULTS
13903	RESULTS
13904	CONCLUSIONS
13905	CONCLUSIONS
13906	BACKGROUND
13907	BACKGROUND
13908	BACKGROUND
13909	METHODS
13910	METHODS
13911	METHODS
13912	METHODS
13913	RESULTS
13914	RESULTS
13915	RESULTS
13916	RESULTS
13917	RESULTS
13918	CONCLUSIONS
13919	OBJECTIVE
13920	METHODS
13921	METHODS
13922	METHODS
13923	METHODS
13924	RESULTS
13925	RESULTS
13926	RESULTS
13927	RESULTS
13928	RESULTS
13929	RESULTS
13930	RESULTS
13931	RESULTS
13932	RESULTS
13933	RESULTS
13934	CONCLUSIONS
13935	RESULTS
13936	BACKGROUND
13937	OBJECTIVE
13938	METHODS
13939	METHODS
13940	METHODS
13941	METHODS
13942	METHODS
13943	RESULTS
13944	RESULTS
13945	RESULTS
13946	CONCLUSIONS
13947	BACKGROUND
13948	OBJECTIVE
13949	METHODS
13950	OBJECTIVE
13951	METHODS
13952	METHODS
13953	METHODS
13954	RESULTS
13955	RESULTS
13956	CONCLUSIONS
13957	BACKGROUND
13958	BACKGROUND
13959	OBJECTIVE
13960	METHODS
13961	METHODS
13962	METHODS
13963	RESULTS
13964	RESULTS
13965	RESULTS
13966	RESULTS
13967	CONCLUSIONS
13968	RESULTS
13969	CONCLUSIONS
13970	OBJECTIVE
13971	METHODS
13972	METHODS
13973	METHODS
13974	RESULTS
13975	RESULTS
13976	RESULTS
13977	CONCLUSIONS
13978	RESULTS
13979	CONCLUSIONS
13980	CONCLUSIONS
13981	BACKGROUND
13982	OBJECTIVE
13983	METHODS
13984	METHODS
13985	RESULTS
13986	RESULTS
13987	CONCLUSIONS
13988	BACKGROUND
13989	BACKGROUND
13990	BACKGROUND
13991	BACKGROUND
13992	BACKGROUND
13993	CONCLUSIONS
13994	METHODS
13995	CONCLUSIONS
13996	METHODS
13997	METHODS
13998	METHODS
13999	METHODS
14000	METHODS
14001	BACKGROUND
14002	BACKGROUND
14003	BACKGROUND
14004	OBJECTIVE
14005	METHODS
14006	METHODS
14007	METHODS
14008	METHODS
14009	METHODS
14010	METHODS
14011	METHODS
14012	RESULTS
14013	RESULTS
14014	RESULTS
14015	RESULTS
14016	RESULTS
14017	CONCLUSIONS
14018	RESULTS
14019	RESULTS
14020	CONCLUSIONS
14021	OBJECTIVE
14022	METHODS
14023	METHODS
14024	METHODS
14025	METHODS
14026	METHODS
14027	METHODS
14028	RESULTS
14029	RESULTS
14030	RESULTS
14031	CONCLUSIONS
14032	BACKGROUND
14033	METHODS
14034	RESULTS
14035	METHODS
14036	RESULTS
14037	RESULTS
14038	RESULTS
14039	CONCLUSIONS
14040	BACKGROUND
14041	OBJECTIVE
14042	METHODS
14043	METHODS
14044	RESULTS
14045	RESULTS
14046	RESULTS
14047	CONCLUSIONS
14048	OBJECTIVE
14049	METHODS
14050	METHODS
14051	METHODS
14052	METHODS
14053	RESULTS
14054	RESULTS
14055	CONCLUSIONS
14056	CONCLUSIONS
14057	CONCLUSIONS
14058	CONCLUSIONS
14059	OBJECTIVE
14060	METHODS
14061	METHODS
14062	METHODS
14063	METHODS
14064	RESULTS
14065	RESULTS
14066	RESULTS
14067	CONCLUSIONS
14068	CONCLUSIONS
14069	BACKGROUND
14070	OBJECTIVE
14071	METHODS
14072	METHODS
14073	METHODS
14074	RESULTS
14075	RESULTS
14076	RESULTS
14077	RESULTS
14078	RESULTS
14079	RESULTS
14080	CONCLUSIONS
14081	OBJECTIVE
14082	METHODS
14083	METHODS
14084	METHODS
14085	RESULTS
14086	RESULTS
14087	RESULTS
14088	CONCLUSIONS
14089	BACKGROUND
14090	METHODS
14091	METHODS
14092	RESULTS
14093	RESULTS
14094	CONCLUSIONS
14095	OBJECTIVE
14096	OBJECTIVE
14097	METHODS
14098	METHODS
14099	METHODS
14100	METHODS
14101	METHODS
14102	METHODS
14103	RESULTS
14104	METHODS
14105	METHODS
14106	RESULTS
14107	RESULTS
14108	RESULTS
14109	RESULTS
14110	CONCLUSIONS
14111	BACKGROUND
14112	OBJECTIVE
14113	METHODS
14114	METHODS
14115	METHODS
14116	RESULTS
14117	RESULTS
14118	METHODS
14119	RESULTS
14120	RESULTS
14121	RESULTS
14122	OBJECTIVE
14123	METHODS
14124	METHODS
14125	METHODS
14126	METHODS
14127	METHODS
14128	RESULTS
14129	CONCLUSIONS
14130	OBJECTIVE
14131	METHODS
14132	METHODS
14133	RESULTS
14134	RESULTS
14135	RESULTS
14136	RESULTS
14137	RESULTS
14138	RESULTS
14139	RESULTS
14140	CONCLUSIONS
14141	BACKGROUND
14142	CONCLUSIONS
14143	METHODS
14144	METHODS
14145	RESULTS
14146	RESULTS
14147	RESULTS
14148	RESULTS
14149	RESULTS
14150	RESULTS
14151	RESULTS
14152	RESULTS
14153	CONCLUSIONS
14154	CONCLUSIONS
14155	CONCLUSIONS
14156	BACKGROUND
14157	OBJECTIVE
14158	METHODS
14159	METHODS
14160	METHODS
14161	METHODS
14162	METHODS
14163	RESULTS
14164	RESULTS
14165	RESULTS
14166	CONCLUSIONS
14167	BACKGROUND
14168	BACKGROUND
14169	METHODS
14170	METHODS
14171	METHODS
14172	RESULTS
14173	RESULTS
14174	RESULTS
14175	CONCLUSIONS
14176	CONCLUSIONS
14177	CONCLUSIONS
14178	BACKGROUND
14179	OBJECTIVE
14180	METHODS
14181	METHODS
14182	METHODS
14183	RESULTS
14184	RESULTS
14185	RESULTS
14186	CONCLUSIONS
14187	OBJECTIVE
14188	METHODS
14189	METHODS
14190	METHODS
14191	METHODS
14192	METHODS
14193	RESULTS
14194	RESULTS
14195	RESULTS
14196	RESULTS
14197	RESULTS
14198	CONCLUSIONS
14199	BACKGROUND
14200	BACKGROUND
14201	BACKGROUND
14202	BACKGROUND
14203	BACKGROUND
14204	METHODS
14205	METHODS
14206	METHODS
14207	METHODS
14208	METHODS
14209	CONCLUSIONS
14210	CONCLUSIONS
14211	BACKGROUND
14212	BACKGROUND
14213	BACKGROUND
14214	METHODS
14215	METHODS
14216	METHODS
14217	METHODS
14218	RESULTS
14219	RESULTS
14220	RESULTS
14221	CONCLUSIONS
14222	RESULTS
14223	BACKGROUND
14224	BACKGROUND
14225	OBJECTIVE
14226	METHODS
14227	METHODS
14228	METHODS
14229	METHODS
14230	METHODS
14231	RESULTS
14232	RESULTS
14233	RESULTS
14234	RESULTS
14235	CONCLUSIONS
14236	BACKGROUND
14237	BACKGROUND
14238	BACKGROUND
14239	BACKGROUND
14240	METHODS
14241	METHODS
14242	METHODS
14243	METHODS
14244	BACKGROUND
14245	BACKGROUND
14246	BACKGROUND
14247	BACKGROUND
14248	BACKGROUND
14249	BACKGROUND
14250	BACKGROUND
14251	BACKGROUND
14252	BACKGROUND
14253	METHODS
14254	METHODS
14255	RESULTS
14256	RESULTS
14257	RESULTS
14258	RESULTS
14259	CONCLUSIONS
14260	BACKGROUND
14261	BACKGROUND
14262	METHODS
14263	METHODS
14264	METHODS
14265	METHODS
14266	RESULTS
14267	CONCLUSIONS
14268	RESULTS
14269	RESULTS
14270	CONCLUSIONS
14271	BACKGROUND
14272	OBJECTIVE
14273	METHODS
14274	METHODS
14275	METHODS
14276	RESULTS
14277	RESULTS
14278	RESULTS
14279	RESULTS
14280	RESULTS
14281	RESULTS
14282	CONCLUSIONS
14283	CONCLUSIONS
14284	BACKGROUND
14285	METHODS
14286	RESULTS
14287	RESULTS
14288	CONCLUSIONS
14289	OBJECTIVE
14290	BACKGROUND
14291	BACKGROUND
14292	OBJECTIVE
14293	METHODS
14294	METHODS
14295	METHODS
14296	METHODS
14297	METHODS
14298	METHODS
14299	RESULTS
14300	RESULTS
14301	RESULTS
14302	RESULTS
14303	RESULTS
14304	RESULTS
14305	BACKGROUND
14306	CONCLUSIONS
14307	CONCLUSIONS
14308	BACKGROUND
14309	OBJECTIVE
14310	METHODS
14311	METHODS
14312	METHODS
14313	METHODS
14314	METHODS
14315	METHODS
14316	RESULTS
14317	RESULTS
14318	RESULTS
14319	CONCLUSIONS
14320	OBJECTIVE
14321	METHODS
14322	METHODS
14323	METHODS
14324	METHODS
14325	RESULTS
14326	RESULTS
14327	RESULTS
14328	RESULTS
14329	RESULTS
14330	RESULTS
14331	RESULTS
14332	CONCLUSIONS
14333	OBJECTIVE
14334	BACKGROUND
14335	BACKGROUND
14336	METHODS
14337	METHODS
14338	METHODS
14339	METHODS
14340	METHODS
14341	METHODS
14342	METHODS
14343	METHODS
14344	RESULTS
14345	RESULTS
14346	RESULTS
14347	RESULTS
14348	RESULTS
14349	CONCLUSIONS
14350	RESULTS
14351	CONCLUSIONS
14352	CONCLUSIONS
14353	OBJECTIVE
14354	OBJECTIVE
14355	METHODS
14356	METHODS
14357	METHODS
14358	RESULTS
14359	RESULTS
14360	CONCLUSIONS
14361	CONCLUSIONS
14362	BACKGROUND
14363	OBJECTIVE
14364	METHODS
14365	METHODS
14366	METHODS
14367	METHODS
14368	RESULTS
14369	RESULTS
14370	RESULTS
14371	CONCLUSIONS
14372	RESULTS
14373	CONCLUSIONS
14374	CONCLUSIONS
14375	OBJECTIVE
14376	METHODS
14377	METHODS
14378	METHODS
14379	METHODS
14380	METHODS
14381	RESULTS
14382	RESULTS
14383	RESULTS
14384	RESULTS
14385	RESULTS
14386	CONCLUSIONS
14387	CONCLUSIONS
14388	OBJECTIVE
14389	METHODS
14390	METHODS
14391	METHODS
14392	METHODS
14393	RESULTS
14394	RESULTS
14395	RESULTS
14396	CONCLUSIONS
14397	OBJECTIVE
14398	METHODS
14399	METHODS
14400	METHODS
14401	METHODS
14402	RESULTS
14403	RESULTS
14404	RESULTS
14405	CONCLUSIONS
14406	CONCLUSIONS
14407	OBJECTIVE
14408	METHODS
14409	METHODS
14410	METHODS
14411	METHODS
14412	METHODS
14413	METHODS
14414	RESULTS
14415	RESULTS
14416	CONCLUSIONS
14417	CONCLUSIONS
14418	BACKGROUND
14419	BACKGROUND
14420	CONCLUSIONS
14421	BACKGROUND
14422	BACKGROUND
14423	METHODS
14424	METHODS
14425	METHODS
14426	RESULTS
14427	RESULTS
14428	RESULTS
14429	RESULTS
14430	CONCLUSIONS
14431	RESULTS
14432	BACKGROUND
14433	BACKGROUND
14434	OBJECTIVE
14435	OBJECTIVE
14436	METHODS
14437	RESULTS
14438	RESULTS
14439	RESULTS
14440	RESULTS
14441	CONCLUSIONS
14442	OBJECTIVE
14443	METHODS
14444	METHODS
14445	METHODS
14446	METHODS
14447	METHODS
14448	RESULTS
14449	RESULTS
14450	RESULTS
14451	CONCLUSIONS
14452	CONCLUSIONS
14453	BACKGROUND
14454	BACKGROUND
14455	METHODS
14456	METHODS
14457	RESULTS
14458	RESULTS
14459	CONCLUSIONS
14460	BACKGROUND
14461	BACKGROUND
14462	OBJECTIVE
14463	METHODS
14464	METHODS
14465	METHODS
14466	METHODS
14467	METHODS
14468	METHODS
14469	METHODS
14470	RESULTS
14471	RESULTS
14472	RESULTS
14473	RESULTS
14474	CONCLUSIONS
14475	OBJECTIVE
14476	METHODS
14477	METHODS
14478	METHODS
14479	RESULTS
14480	RESULTS
14481	RESULTS
14482	CONCLUSIONS
14483	OBJECTIVE
14484	METHODS
14485	OBJECTIVE
14486	METHODS
14487	RESULTS
14488	RESULTS
14489	RESULTS
14490	CONCLUSIONS
14491	BACKGROUND
14492	OBJECTIVE
14493	METHODS
14494	METHODS
14495	RESULTS
14496	RESULTS
14497	RESULTS
14498	RESULTS
14499	RESULTS
14500	RESULTS
14501	CONCLUSIONS
14502	BACKGROUND
14503	OBJECTIVE
14504	METHODS
14505	METHODS
14506	METHODS
14507	METHODS
14508	RESULTS
14509	RESULTS
14510	RESULTS
14511	RESULTS
14512	RESULTS
14513	RESULTS
14514	CONCLUSIONS
14515	CONCLUSIONS
14516	BACKGROUND
14517	BACKGROUND
14518	BACKGROUND
14519	METHODS
14520	METHODS
14521	RESULTS
14522	METHODS
14523	METHODS
14524	OBJECTIVE
14525	METHODS
14526	METHODS
14527	RESULTS
14528	RESULTS
14529	CONCLUSIONS
14530	RESULTS
14531	BACKGROUND
14532	OBJECTIVE
14533	METHODS
14534	METHODS
14535	METHODS
14536	METHODS
14537	METHODS
14538	METHODS
14539	METHODS
14540	METHODS
14541	METHODS
14542	METHODS
14543	METHODS
14544	RESULTS
14545	BACKGROUND
14546	CONCLUSIONS
14547	BACKGROUND
14548	BACKGROUND
14549	OBJECTIVE
14550	METHODS
14551	METHODS
14552	METHODS
14553	METHODS
14554	METHODS
14555	METHODS
14556	RESULTS
14557	RESULTS
14558	RESULTS
14559	CONCLUSIONS
14560	BACKGROUND
14561	BACKGROUND
14562	OBJECTIVE
14563	METHODS
14564	RESULTS
14565	METHODS
14566	RESULTS
14567	RESULTS
14568	CONCLUSIONS
14569	BACKGROUND
14570	BACKGROUND
14571	OBJECTIVE
14572	METHODS
14573	METHODS
14574	METHODS
14575	METHODS
14576	METHODS
14577	RESULTS
14578	RESULTS
14579	RESULTS
14580	RESULTS
14581	RESULTS
14582	CONCLUSIONS
14583	OBJECTIVE
14584	METHODS
14585	METHODS
14586	RESULTS
14587	METHODS
14588	RESULTS
14589	RESULTS
14590	RESULTS
14591	RESULTS
14592	CONCLUSIONS
14593	BACKGROUND
14594	OBJECTIVE
14595	METHODS
14596	RESULTS
14597	METHODS
14598	METHODS
14599	METHODS
14600	RESULTS
14601	RESULTS
14602	RESULTS
14603	RESULTS
14604	RESULTS
14605	CONCLUSIONS
14606	BACKGROUND
14607	BACKGROUND
14608	BACKGROUND
14609	BACKGROUND
14610	BACKGROUND
14611	OBJECTIVE
14612	METHODS
14613	METHODS
14614	METHODS
14615	METHODS
14616	METHODS
14617	RESULTS
14618	RESULTS
14619	RESULTS
14620	RESULTS
14621	RESULTS
14622	CONCLUSIONS
14623	OBJECTIVE
14624	METHODS
14625	METHODS
14626	METHODS
14627	METHODS
14628	METHODS
14629	METHODS
14630	RESULTS
14631	RESULTS
14632	RESULTS
14633	RESULTS
14634	RESULTS
14635	RESULTS
14636	RESULTS
14637	CONCLUSIONS
14638	METHODS
14639	METHODS
14640	RESULTS
14641	RESULTS
14642	RESULTS
14643	RESULTS
14644	RESULTS
14645	OBJECTIVE
14646	METHODS
14647	BACKGROUND
14648	METHODS
14649	METHODS
14650	METHODS
14651	METHODS
14652	METHODS
14653	RESULTS
14654	RESULTS
14655	RESULTS
14656	RESULTS
14657	RESULTS
14658	BACKGROUND
14659	CONCLUSIONS
14660	OBJECTIVE
14661	METHODS
14662	METHODS
14663	METHODS
14664	RESULTS
14665	RESULTS
14666	RESULTS
14667	RESULTS
14668	RESULTS
14669	RESULTS
14670	RESULTS
14671	CONCLUSIONS
14672	CONCLUSIONS
14673	BACKGROUND
14674	OBJECTIVE
14675	METHODS
14676	METHODS
14677	RESULTS
14678	RESULTS
14679	RESULTS
14680	RESULTS
14681	RESULTS
14682	CONCLUSIONS
14683	BACKGROUND
14684	BACKGROUND
14685	OBJECTIVE
14686	METHODS
14687	RESULTS
14688	RESULTS
14689	RESULTS
14690	RESULTS
14691	RESULTS
14692	CONCLUSIONS
14693	CONCLUSIONS
14694	CONCLUSIONS
14695	CONCLUSIONS
14696	OBJECTIVE
14697	METHODS
14698	METHODS
14699	METHODS
14700	METHODS
14701	METHODS
14702	RESULTS
14703	RESULTS
14704	CONCLUSIONS
14705	BACKGROUND
14706	OBJECTIVE
14707	METHODS
14708	METHODS
14709	METHODS
14710	RESULTS
14711	RESULTS
14712	RESULTS
14713	RESULTS
14714	RESULTS
14715	CONCLUSIONS
14716	RESULTS
14717	BACKGROUND
14718	RESULTS
14719	METHODS
14720	METHODS
14721	RESULTS
14722	RESULTS
14723	RESULTS
14724	RESULTS
14725	CONCLUSIONS
14726	BACKGROUND
14727	BACKGROUND
14728	METHODS
14729	METHODS
14730	RESULTS
14731	RESULTS
14732	RESULTS
14733	RESULTS
14734	RESULTS
14735	CONCLUSIONS
14736	CONCLUSIONS
14737	BACKGROUND
14738	BACKGROUND
14739	BACKGROUND
14740	BACKGROUND
14741	METHODS
14742	METHODS
14743	RESULTS
14744	RESULTS
14745	RESULTS
14746	CONCLUSIONS
14747	CONCLUSIONS
14748	BACKGROUND
14749	OBJECTIVE
14750	METHODS
14751	METHODS
14752	METHODS
14753	METHODS
14754	RESULTS
14755	RESULTS
14756	RESULTS
14757	RESULTS
14758	CONCLUSIONS
14759	OBJECTIVE
14760	METHODS
14761	METHODS
14762	METHODS
14763	METHODS
14764	METHODS
14765	METHODS
14766	RESULTS
14767	RESULTS
14768	RESULTS
14769	RESULTS
14770	RESULTS
14771	CONCLUSIONS
14772	BACKGROUND
14773	OBJECTIVE
14774	METHODS
14775	METHODS
14776	METHODS
14777	RESULTS
14778	RESULTS
14779	RESULTS
14780	RESULTS
14781	CONCLUSIONS
14782	RESULTS
14783	METHODS
14784	OBJECTIVE
14785	METHODS
14786	METHODS
14787	METHODS
14788	METHODS
14789	RESULTS
14790	RESULTS
14791	RESULTS
14792	CONCLUSIONS
14793	BACKGROUND
14794	OBJECTIVE
14795	METHODS
14796	METHODS
14797	METHODS
14798	METHODS
14799	METHODS
14800	RESULTS
14801	RESULTS
14802	CONCLUSIONS
14803	OBJECTIVE
14804	OBJECTIVE
14805	METHODS
14806	METHODS
14807	METHODS
14808	METHODS
14809	RESULTS
14810	RESULTS
14811	RESULTS
14812	RESULTS
14813	CONCLUSIONS
14814	CONCLUSIONS
14815	OBJECTIVE
14816	METHODS
14817	METHODS
14818	METHODS
14819	METHODS
14820	RESULTS
14821	CONCLUSIONS
14822	RESULTS
14823	RESULTS
14824	CONCLUSIONS
14825	CONCLUSIONS
14826	CONCLUSIONS
14827	BACKGROUND
14828	BACKGROUND
14829	OBJECTIVE
14830	METHODS
14831	METHODS
14832	METHODS
14833	METHODS
14834	RESULTS
14835	RESULTS
14836	RESULTS
14837	CONCLUSIONS
14838	CONCLUSIONS
14839	OBJECTIVE
14840	OBJECTIVE
14841	METHODS
14842	METHODS
14843	METHODS
14844	RESULTS
14845	RESULTS
14846	RESULTS
14847	CONCLUSIONS
14848	CONCLUSIONS
14849	BACKGROUND
14850	OBJECTIVE
14851	METHODS
14852	METHODS
14853	METHODS
14854	METHODS
14855	METHODS
14856	METHODS
14857	METHODS
14858	RESULTS
14859	RESULTS
14860	CONCLUSIONS
14861	OBJECTIVE
14862	RESULTS
14863	METHODS
14864	METHODS
14865	RESULTS
14866	RESULTS
14867	RESULTS
14868	CONCLUSIONS
14869	OBJECTIVE
14870	METHODS
14871	METHODS
14872	METHODS
14873	METHODS
14874	METHODS
14875	METHODS
14876	METHODS
14877	METHODS
14878	METHODS
14879	METHODS
14880	METHODS
14881	METHODS
14882	RESULTS
14883	RESULTS
14884	RESULTS
14885	RESULTS
14886	RESULTS
14887	RESULTS
14888	RESULTS
14889	RESULTS
14890	RESULTS
14891	RESULTS
14892	RESULTS
14893	BACKGROUND
14894	BACKGROUND
14895	METHODS
14896	METHODS
14897	METHODS
14898	METHODS
14899	RESULTS
14900	RESULTS
14901	CONCLUSIONS
14902	CONCLUSIONS
14903	BACKGROUND
14904	OBJECTIVE
14905	METHODS
14906	METHODS
14907	METHODS
14908	METHODS
14909	RESULTS
14910	RESULTS
14911	RESULTS
14912	CONCLUSIONS
14913	BACKGROUND
14914	BACKGROUND
14915	BACKGROUND
14916	METHODS
14917	METHODS
14918	METHODS
14919	RESULTS
14920	CONCLUSIONS
14921	CONCLUSIONS
14922	BACKGROUND
14923	OBJECTIVE
14924	METHODS
14925	METHODS
14926	RESULTS
14927	RESULTS
14928	RESULTS
14929	RESULTS
14930	RESULTS
14931	CONCLUSIONS
14932	OBJECTIVE
14933	METHODS
14934	METHODS
14935	RESULTS
14936	RESULTS
14937	RESULTS
14938	CONCLUSIONS
14939	OBJECTIVE
14940	METHODS
14941	METHODS
14942	METHODS
14943	RESULTS
14944	RESULTS
14945	CONCLUSIONS
14946	OBJECTIVE
14947	METHODS
14948	METHODS
14949	METHODS
14950	METHODS
14951	RESULTS
14952	RESULTS
14953	RESULTS
14954	RESULTS
14955	RESULTS
14956	BACKGROUND
14957	CONCLUSIONS
14958	CONCLUSIONS
14959	METHODS
14960	METHODS
14961	METHODS
14962	METHODS
14963	METHODS
14964	METHODS
14965	METHODS
14966	RESULTS
14967	RESULTS
14968	RESULTS
14969	RESULTS
14970	RESULTS
14971	CONCLUSIONS
14972	OBJECTIVE
14973	METHODS
14974	METHODS
14975	METHODS
14976	METHODS
14977	RESULTS
14978	RESULTS
14979	RESULTS
14980	RESULTS
14981	CONCLUSIONS
14982	OBJECTIVE
14983	METHODS
14984	METHODS
14985	METHODS
14986	METHODS
14987	METHODS
14988	METHODS
14989	RESULTS
14990	RESULTS
14991	RESULTS
14992	RESULTS
14993	CONCLUSIONS
14994	CONCLUSIONS
14995	CONCLUSIONS
14996	OBJECTIVE
14997	METHODS
14998	RESULTS
14999	METHODS
15000	METHODS
15001	RESULTS
15002	RESULTS
15003	RESULTS
15004	CONCLUSIONS
15005	CONCLUSIONS
15006	OBJECTIVE
15007	METHODS
15008	METHODS
15009	METHODS
15010	METHODS
15011	METHODS
15012	METHODS
15013	METHODS
15014	RESULTS
15015	RESULTS
15016	RESULTS
15017	RESULTS
15018	BACKGROUND
15019	RESULTS
15020	BACKGROUND
15021	OBJECTIVE
15022	METHODS
15023	METHODS
15024	METHODS
15025	METHODS
15026	RESULTS
15027	RESULTS
15028	RESULTS
15029	CONCLUSIONS
15030	CONCLUSIONS
15031	BACKGROUND
15032	BACKGROUND
15033	BACKGROUND
15034	METHODS
15035	METHODS
15036	CONCLUSIONS
15037	METHODS
15038	RESULTS
15039	RESULTS
15040	RESULTS
15041	RESULTS
15042	CONCLUSIONS
15043	CONCLUSIONS
15044	CONCLUSIONS
15045	OBJECTIVE
15046	METHODS
15047	METHODS
15048	METHODS
15049	METHODS
15050	METHODS
15051	RESULTS
15052	RESULTS
15053	RESULTS
15054	RESULTS
15055	CONCLUSIONS
15056	BACKGROUND
15057	OBJECTIVE
15058	METHODS
15059	METHODS
15060	METHODS
15061	METHODS
15062	RESULTS
15063	CONCLUSIONS
15064	CONCLUSIONS
15065	BACKGROUND
15066	METHODS
15067	METHODS
15068	RESULTS
15069	RESULTS
15070	RESULTS
15071	RESULTS
15072	RESULTS
15073	CONCLUSIONS
15074	OBJECTIVE
15075	METHODS
15076	METHODS
15077	METHODS
15078	METHODS
15079	RESULTS
15080	RESULTS
15081	CONCLUSIONS
15082	BACKGROUND
15083	BACKGROUND
15084	OBJECTIVE
15085	METHODS
15086	METHODS
15087	RESULTS
15088	RESULTS
15089	RESULTS
15090	RESULTS
15091	RESULTS
15092	RESULTS
15093	RESULTS
15094	RESULTS
15095	RESULTS
15096	CONCLUSIONS
15097	CONCLUSIONS
15098	BACKGROUND
15099	OBJECTIVE
15100	METHODS
15101	METHODS
15102	RESULTS
15103	RESULTS
15104	RESULTS
15105	RESULTS
15106	RESULTS
15107	RESULTS
15108	CONCLUSIONS
15109	CONCLUSIONS
15110	OBJECTIVE
15111	METHODS
15112	METHODS
15113	METHODS
15114	METHODS
15115	METHODS
15116	RESULTS
15117	RESULTS
15118	RESULTS
15119	RESULTS
15120	RESULTS
15121	CONCLUSIONS
15122	BACKGROUND
15123	OBJECTIVE
15124	METHODS
15125	METHODS
15126	METHODS
15127	METHODS
15128	METHODS
15129	RESULTS
15130	RESULTS
15131	RESULTS
15132	RESULTS
15133	CONCLUSIONS
15134	CONCLUSIONS
15135	OBJECTIVE
15136	METHODS
15137	METHODS
15138	METHODS
15139	METHODS
15140	RESULTS
15141	RESULTS
15142	RESULTS
15143	RESULTS
15144	CONCLUSIONS
15145	CONCLUSIONS
15146	BACKGROUND
15147	BACKGROUND
15148	BACKGROUND
15149	BACKGROUND
15150	BACKGROUND
15151	OBJECTIVE
15152	METHODS
15153	METHODS
15154	RESULTS
15155	RESULTS
15156	RESULTS
15157	RESULTS
15158	RESULTS
15159	RESULTS
15160	CONCLUSIONS
15161	OBJECTIVE
15162	METHODS
15163	RESULTS
15164	RESULTS
15165	CONCLUSIONS
15166	CONCLUSIONS
15167	OBJECTIVE
15168	METHODS
15169	METHODS
15170	METHODS
15171	RESULTS
15172	RESULTS
15173	RESULTS
15174	RESULTS
15175	CONCLUSIONS
15176	CONCLUSIONS
15177	BACKGROUND
15178	OBJECTIVE
15179	METHODS
15180	METHODS
15181	RESULTS
15182	RESULTS
15183	RESULTS
15184	RESULTS
15185	RESULTS
15186	RESULTS
15187	CONCLUSIONS
15188	BACKGROUND
15189	METHODS
15190	METHODS
15191	METHODS
15192	METHODS
15193	METHODS
15194	RESULTS
15195	RESULTS
15196	RESULTS
15197	CONCLUSIONS
15198	CONCLUSIONS
15199	BACKGROUND
15200	BACKGROUND
15201	BACKGROUND
15202	METHODS
15203	METHODS
15204	METHODS
15205	RESULTS
15206	RESULTS
15207	RESULTS
15208	CONCLUSIONS
15209	CONCLUSIONS
15210	OBJECTIVE
15211	METHODS
15212	METHODS
15213	METHODS
15214	METHODS
15215	METHODS
15216	METHODS
15217	RESULTS
15218	RESULTS
15219	CONCLUSIONS
15220	BACKGROUND
15221	OBJECTIVE
15222	METHODS
15223	METHODS
15224	METHODS
15225	METHODS
15226	METHODS
15227	RESULTS
15228	CONCLUSIONS
15229	CONCLUSIONS
15230	CONCLUSIONS
15231	CONCLUSIONS
15232	BACKGROUND
15233	BACKGROUND
15234	BACKGROUND
15235	METHODS
15236	METHODS
15237	METHODS
15238	METHODS
15239	RESULTS
15240	RESULTS
15241	RESULTS
15242	RESULTS
15243	RESULTS
15244	RESULTS
15245	CONCLUSIONS
15246	RESULTS
15247	CONCLUSIONS
15248	BACKGROUND
15249	BACKGROUND
15250	OBJECTIVE
15251	METHODS
15252	METHODS
15253	METHODS
15254	METHODS
15255	METHODS
15256	RESULTS
15257	RESULTS
15258	RESULTS
15259	CONCLUSIONS
15260	CONCLUSIONS
15261	BACKGROUND
15262	METHODS
15263	METHODS
15264	METHODS
15265	METHODS
15266	METHODS
15267	RESULTS
15268	RESULTS
15269	METHODS
15270	CONCLUSIONS
15271	RESULTS
15272	OBJECTIVE
15273	METHODS
15274	METHODS
15275	METHODS
15276	METHODS
15277	METHODS
15278	RESULTS
15279	RESULTS
15280	RESULTS
15281	RESULTS
15282	RESULTS
15283	RESULTS
15284	CONCLUSIONS
15285	CONCLUSIONS
15286	CONCLUSIONS
15287	BACKGROUND
15288	OBJECTIVE
15289	METHODS
15290	METHODS
15291	METHODS
15292	METHODS
15293	METHODS
15294	METHODS
15295	RESULTS
15296	RESULTS
15297	RESULTS
15298	CONCLUSIONS
15299	BACKGROUND
15300	BACKGROUND
15301	BACKGROUND
15302	BACKGROUND
15303	METHODS
15304	METHODS
15305	RESULTS
15306	RESULTS
15307	RESULTS
15308	RESULTS
15309	RESULTS
15310	CONCLUSIONS
15311	CONCLUSIONS
15312	OBJECTIVE
15313	BACKGROUND
15314	BACKGROUND
15315	BACKGROUND
15316	METHODS
15317	METHODS
15318	METHODS
15319	METHODS
15320	RESULTS
15321	RESULTS
15322	RESULTS
15323	RESULTS
15324	RESULTS
15325	RESULTS
15326	RESULTS
15327	RESULTS
15328	RESULTS
15329	RESULTS
15330	RESULTS
15331	RESULTS
15332	CONCLUSIONS
15333	CONCLUSIONS
15334	BACKGROUND
15335	METHODS
15336	METHODS
15337	RESULTS
15338	RESULTS
15339	CONCLUSIONS
15340	OBJECTIVE
15341	METHODS
15342	METHODS
15343	METHODS
15344	METHODS
15345	METHODS
15346	METHODS
15347	RESULTS
15348	RESULTS
15349	RESULTS
15350	RESULTS
15351	CONCLUSIONS
15352	CONCLUSIONS
15353	OBJECTIVE
15354	METHODS
15355	METHODS
15356	METHODS
15357	METHODS
15358	METHODS
15359	RESULTS
15360	RESULTS
15361	RESULTS
15362	RESULTS
15363	RESULTS
15364	RESULTS
15365	RESULTS
15366	RESULTS
15367	CONCLUSIONS
15368	RESULTS
15369	OBJECTIVE
15370	METHODS
15371	METHODS
15372	METHODS
15373	METHODS
15374	METHODS
15375	METHODS
15376	METHODS
15377	RESULTS
15378	RESULTS
15379	RESULTS
15380	CONCLUSIONS
15381	OBJECTIVE
15382	METHODS
15383	METHODS
15384	RESULTS
15385	RESULTS
15386	RESULTS
15387	RESULTS
15388	RESULTS
15389	RESULTS
15390	RESULTS
15391	CONCLUSIONS
15392	CONCLUSIONS
15393	RESULTS
15394	OBJECTIVE
15395	METHODS
15396	METHODS
15397	METHODS
15398	METHODS
15399	RESULTS
15400	RESULTS
15401	RESULTS
15402	RESULTS
15403	CONCLUSIONS
15404	CONCLUSIONS
15405	BACKGROUND
15406	OBJECTIVE
15407	METHODS
15408	METHODS
15409	METHODS
15410	METHODS
15411	RESULTS
15412	RESULTS
15413	RESULTS
15414	RESULTS
15415	CONCLUSIONS
15416	BACKGROUND
15417	BACKGROUND
15418	METHODS
15419	METHODS
15420	METHODS
15421	METHODS
15422	METHODS
15423	METHODS
15424	RESULTS
15425	RESULTS
15426	RESULTS
15427	RESULTS
15428	RESULTS
15429	RESULTS
15430	RESULTS
15431	OBJECTIVE
15432	METHODS
15433	METHODS
15434	METHODS
15435	METHODS
15436	METHODS
15437	METHODS
15438	METHODS
15439	METHODS
15440	RESULTS
15441	RESULTS
15442	RESULTS
15443	RESULTS
15444	CONCLUSIONS
15445	OBJECTIVE
15446	METHODS
15447	METHODS
15448	METHODS
15449	RESULTS
15450	RESULTS
15451	CONCLUSIONS
15452	CONCLUSIONS
15453	OBJECTIVE
15454	METHODS
15455	METHODS
15456	RESULTS
15457	RESULTS
15458	RESULTS
15459	RESULTS
15460	RESULTS
15461	RESULTS
15462	CONCLUSIONS
15463	OBJECTIVE
15464	METHODS
15465	METHODS
15466	RESULTS
15467	RESULTS
15468	RESULTS
15469	RESULTS
15470	RESULTS
15471	CONCLUSIONS
15472	CONCLUSIONS
15473	RESULTS
15474	RESULTS
15475	OBJECTIVE
15476	OBJECTIVE
15477	METHODS
15478	METHODS
15479	RESULTS
15480	RESULTS
15481	RESULTS
15482	RESULTS
15483	RESULTS
15484	CONCLUSIONS
15485	RESULTS
15486	METHODS
15487	OBJECTIVE
15488	METHODS
15489	METHODS
15490	METHODS
15491	METHODS
15492	METHODS
15493	RESULTS
15494	RESULTS
15495	RESULTS
15496	CONCLUSIONS
15497	CONCLUSIONS
15498	BACKGROUND
15499	BACKGROUND
15500	OBJECTIVE
15501	METHODS
15502	METHODS
15503	METHODS
15504	RESULTS
15505	RESULTS
15506	RESULTS
15507	RESULTS
15508	RESULTS
15509	RESULTS
15510	RESULTS
15511	CONCLUSIONS
15512	CONCLUSIONS
15513	CONCLUSIONS
15514	OBJECTIVE
15515	METHODS
15516	METHODS
15517	METHODS
15518	METHODS
15519	METHODS
15520	METHODS
15521	METHODS
15522	RESULTS
15523	RESULTS
15524	CONCLUSIONS
15525	CONCLUSIONS
15526	OBJECTIVE
15527	METHODS
15528	METHODS
15529	METHODS
15530	METHODS
15531	METHODS
15532	METHODS
15533	RESULTS
15534	RESULTS
15535	RESULTS
15536	RESULTS
15537	RESULTS
15538	CONCLUSIONS
15539	OBJECTIVE
15540	METHODS
15541	METHODS
15542	METHODS
15543	METHODS
15544	METHODS
15545	RESULTS
15546	CONCLUSIONS
15547	BACKGROUND
15548	METHODS
15549	METHODS
15550	METHODS
15551	METHODS
15552	RESULTS
15553	RESULTS
15554	RESULTS
15555	RESULTS
15556	RESULTS
15557	RESULTS
15558	RESULTS
15559	RESULTS
15560	RESULTS
15561	RESULTS
15562	CONCLUSIONS
15563	CONCLUSIONS
15564	CONCLUSIONS
15565	CONCLUSIONS
15566	BACKGROUND
15567	OBJECTIVE
15568	METHODS
15569	METHODS
15570	METHODS
15571	RESULTS
15572	RESULTS
15573	RESULTS
15574	RESULTS
15575	RESULTS
15576	CONCLUSIONS
15577	BACKGROUND
15578	METHODS
15579	METHODS
15580	METHODS
15581	METHODS
15582	RESULTS
15583	RESULTS
15584	RESULTS
15585	RESULTS
15586	CONCLUSIONS
15587	CONCLUSIONS
15588	OBJECTIVE
15589	METHODS
15590	METHODS
15591	RESULTS
15592	RESULTS
15593	RESULTS
15594	CONCLUSIONS
15595	BACKGROUND
15596	BACKGROUND
15597	CONCLUSIONS
15598	BACKGROUND
15599	BACKGROUND
15600	METHODS
15601	BACKGROUND
15602	METHODS
15603	METHODS
15604	CONCLUSIONS
15605	BACKGROUND
15606	BACKGROUND
15607	OBJECTIVE
15608	BACKGROUND
15609	OBJECTIVE
15610	METHODS
15611	METHODS
15612	METHODS
15613	RESULTS
15614	RESULTS
15615	RESULTS
15616	CONCLUSIONS
15617	CONCLUSIONS
15618	CONCLUSIONS
15619	OBJECTIVE
15620	OBJECTIVE
15621	METHODS
15622	METHODS
15623	METHODS
15624	METHODS
15625	METHODS
15626	RESULTS
15627	RESULTS
15628	RESULTS
15629	RESULTS
15630	RESULTS
15631	RESULTS
15632	CONCLUSIONS
15633	CONCLUSIONS
15634	OBJECTIVE
15635	METHODS
15636	METHODS
15637	METHODS
15638	RESULTS
15639	RESULTS
15640	CONCLUSIONS
15641	BACKGROUND
15642	BACKGROUND
15643	OBJECTIVE
15644	METHODS
15645	METHODS
15646	METHODS
15647	RESULTS
15648	RESULTS
15649	RESULTS
15650	RESULTS
15651	RESULTS
15652	RESULTS
15653	CONCLUSIONS
15654	CONCLUSIONS
15655	BACKGROUND
15656	BACKGROUND
15657	METHODS
15658	METHODS
15659	METHODS
15660	METHODS
15661	METHODS
15662	METHODS
15663	METHODS
15664	METHODS
15665	RESULTS
15666	RESULTS
15667	RESULTS
15668	RESULTS
15669	RESULTS
15670	CONCLUSIONS
15671	BACKGROUND
15672	BACKGROUND
15673	METHODS
15674	METHODS
15675	OBJECTIVE
15676	METHODS
15677	METHODS
15678	METHODS
15679	RESULTS
15680	RESULTS
15681	RESULTS
15682	RESULTS
15683	RESULTS
15684	CONCLUSIONS
15685	BACKGROUND
15686	BACKGROUND
15687	OBJECTIVE
15688	OBJECTIVE
15689	METHODS
15690	METHODS
15691	METHODS
15692	METHODS
15693	METHODS
15694	METHODS
15695	RESULTS
15696	RESULTS
15697	RESULTS
15698	RESULTS
15699	RESULTS
15700	RESULTS
15701	RESULTS
15702	CONCLUSIONS
15703	OBJECTIVE
15704	METHODS
15705	CONCLUSIONS
15706	METHODS
15707	METHODS
15708	METHODS
15709	RESULTS
15710	CONCLUSIONS
15711	RESULTS
15712	CONCLUSIONS
15713	RESULTS
15714	OBJECTIVE
15715	METHODS
15716	METHODS
15717	METHODS
15718	METHODS
15719	METHODS
15720	RESULTS
15721	RESULTS
15722	RESULTS
15723	RESULTS
15724	RESULTS
15725	CONCLUSIONS
15726	METHODS
15727	METHODS
15728	METHODS
15729	METHODS
15730	RESULTS
15731	RESULTS
15732	RESULTS
15733	CONCLUSIONS
15734	CONCLUSIONS
15735	OBJECTIVE
15736	METHODS
15737	METHODS
15738	METHODS
15739	RESULTS
15740	RESULTS
15741	RESULTS
15742	CONCLUSIONS
15743	CONCLUSIONS
15744	CONCLUSIONS
15745	CONCLUSIONS
15746	BACKGROUND
15747	OBJECTIVE
15748	METHODS
15749	METHODS
15750	METHODS
15751	METHODS
15752	METHODS
15753	RESULTS
15754	RESULTS
15755	RESULTS
15756	RESULTS
15757	RESULTS
15758	RESULTS
15759	CONCLUSIONS
15760	CONCLUSIONS
15761	BACKGROUND
15762	METHODS
15763	METHODS
15764	METHODS
15765	METHODS
15766	METHODS
15767	METHODS
15768	METHODS
15769	METHODS
15770	RESULTS
15771	RESULTS
15772	RESULTS
15773	RESULTS
15774	RESULTS
15775	RESULTS
15776	RESULTS
15777	RESULTS
15778	RESULTS
15779	BACKGROUND
15780	BACKGROUND
15781	BACKGROUND
15782	METHODS
15783	METHODS
15784	METHODS
15785	METHODS
15786	RESULTS
15787	RESULTS
15788	RESULTS
15789	RESULTS
15790	RESULTS
15791	RESULTS
15792	CONCLUSIONS
15793	BACKGROUND
15794	BACKGROUND
15795	BACKGROUND
15796	OBJECTIVE
15797	BACKGROUND
15798	BACKGROUND
15799	BACKGROUND
15800	OBJECTIVE
15801	METHODS
15802	METHODS
15803	METHODS
15804	METHODS
15805	METHODS
15806	METHODS
15807	METHODS
15808	METHODS
15809	RESULTS
15810	RESULTS
15811	RESULTS
15812	RESULTS
15813	RESULTS
15814	CONCLUSIONS
15815	OBJECTIVE
15816	METHODS
15817	METHODS
15818	METHODS
15819	METHODS
15820	RESULTS
15821	RESULTS
15822	RESULTS
15823	CONCLUSIONS
15824	BACKGROUND
15825	BACKGROUND
15826	BACKGROUND
15827	METHODS
15828	METHODS
15829	METHODS
15830	METHODS
15831	METHODS
15832	RESULTS
15833	RESULTS
15834	RESULTS
15835	BACKGROUND
15836	OBJECTIVE
15837	CONCLUSIONS
15838	OBJECTIVE
15839	METHODS
15840	METHODS
15841	METHODS
15842	RESULTS
15843	CONCLUSIONS
15844	CONCLUSIONS
15845	OBJECTIVE
15846	METHODS
15847	METHODS
15848	METHODS
15849	METHODS
15850	METHODS
15851	RESULTS
15852	RESULTS
15853	RESULTS
15854	CONCLUSIONS
15855	CONCLUSIONS
15856	CONCLUSIONS
15857	CONCLUSIONS
15858	CONCLUSIONS
15859	OBJECTIVE
15860	METHODS
15861	METHODS
15862	METHODS
15863	METHODS
15864	RESULTS
15865	RESULTS
15866	RESULTS
15867	RESULTS
15868	RESULTS
15869	CONCLUSIONS
15870	OBJECTIVE
15871	METHODS
15872	METHODS
15873	METHODS
15874	METHODS
15875	METHODS
15876	RESULTS
15877	RESULTS
15878	RESULTS
15879	RESULTS
15880	RESULTS
15881	CONCLUSIONS
15882	CONCLUSIONS
15883	OBJECTIVE
15884	METHODS
15885	METHODS
15886	METHODS
15887	METHODS
15888	METHODS
15889	RESULTS
15890	RESULTS
15891	METHODS
15892	RESULTS
15893	RESULTS
15894	RESULTS
15895	RESULTS
15896	RESULTS
15897	RESULTS
15898	RESULTS
15899	RESULTS
15900	CONCLUSIONS
15901	RESULTS
15902	BACKGROUND
15903	METHODS
15904	METHODS
15905	METHODS
15906	METHODS
15907	METHODS
15908	METHODS
15909	RESULTS
15910	RESULTS
15911	RESULTS
15912	RESULTS
15913	CONCLUSIONS
15914	OBJECTIVE
15915	BACKGROUND
15916	METHODS
15917	METHODS
15918	RESULTS
15919	RESULTS
15920	RESULTS
15921	RESULTS
15922	CONCLUSIONS
15923	CONCLUSIONS
15924	CONCLUSIONS
15925	OBJECTIVE
15926	OBJECTIVE
15927	METHODS
15928	METHODS
15929	METHODS
15930	METHODS
15931	METHODS
15932	RESULTS
15933	RESULTS
15934	RESULTS
15935	RESULTS
15936	RESULTS
15937	RESULTS
15938	CONCLUSIONS
15939	BACKGROUND
15940	BACKGROUND
15941	OBJECTIVE
15942	OBJECTIVE
15943	METHODS
15944	METHODS
15945	METHODS
15946	METHODS
15947	METHODS
15948	RESULTS
15949	RESULTS
15950	CONCLUSIONS
15951	CONCLUSIONS
15952	RESULTS
15953	RESULTS
15954	CONCLUSIONS
15955	CONCLUSIONS
15956	BACKGROUND
15957	OBJECTIVE
15958	METHODS
15959	METHODS
15960	METHODS
15961	METHODS
15962	RESULTS
15963	RESULTS
15964	BACKGROUND
15965	CONCLUSIONS
15966	BACKGROUND
15967	BACKGROUND
15968	METHODS
15969	METHODS
15970	METHODS
15971	METHODS
15972	METHODS
15973	METHODS
15974	METHODS
15975	CONCLUSIONS
15976	CONCLUSIONS
15977	CONCLUSIONS
15978	BACKGROUND
15979	BACKGROUND
15980	OBJECTIVE
15981	METHODS
15982	METHODS
15983	METHODS
15984	METHODS
15985	METHODS
15986	CONCLUSIONS
15987	RESULTS
15988	CONCLUSIONS
15989	OBJECTIVE
15990	BACKGROUND
15991	BACKGROUND
15992	BACKGROUND
15993	METHODS
15994	METHODS
15995	METHODS
15996	METHODS
15997	RESULTS
15998	RESULTS
15999	RESULTS
16000	RESULTS
16001	CONCLUSIONS
16002	OBJECTIVE
16003	METHODS
16004	METHODS
16005	METHODS
16006	METHODS
16007	METHODS
16008	RESULTS
16009	RESULTS
16010	CONCLUSIONS
16011	OBJECTIVE
16012	OBJECTIVE
16013	OBJECTIVE
16014	METHODS
16015	METHODS
16016	RESULTS
16017	RESULTS
16018	RESULTS
16019	RESULTS
16020	RESULTS
16021	CONCLUSIONS
16022	CONCLUSIONS
16023	BACKGROUND
16024	METHODS
16025	METHODS
16026	METHODS
16027	RESULTS
16028	RESULTS
16029	RESULTS
16030	RESULTS
16031	RESULTS
16032	CONCLUSIONS
16033	CONCLUSIONS
16034	OBJECTIVE
16035	METHODS
16036	METHODS
16037	RESULTS
16038	RESULTS
16039	CONCLUSIONS
16040	OBJECTIVE
16041	METHODS
16042	METHODS
16043	METHODS
16044	METHODS
16045	METHODS
16046	RESULTS
16047	RESULTS
16048	RESULTS
16049	RESULTS
16050	CONCLUSIONS
16051	BACKGROUND
16052	CONCLUSIONS
16053	BACKGROUND
16054	OBJECTIVE
16055	METHODS
16056	METHODS
16057	RESULTS
16058	RESULTS
16059	RESULTS
16060	CONCLUSIONS
16061	OBJECTIVE
16062	METHODS
16063	METHODS
16064	RESULTS
16065	METHODS
16066	METHODS
16067	RESULTS
16068	CONCLUSIONS
16069	OBJECTIVE
16070	RESULTS
16071	METHODS
16072	OBJECTIVE
16073	METHODS
16074	RESULTS
16075	METHODS
16076	CONCLUSIONS
16077	CONCLUSIONS
16078	CONCLUSIONS
16079	BACKGROUND
16080	BACKGROUND
16081	CONCLUSIONS
16082	OBJECTIVE
16083	RESULTS
16084	METHODS
16085	METHODS
16086	METHODS
16087	METHODS
16088	METHODS
16089	METHODS
16090	METHODS
16091	METHODS
16092	METHODS
16093	METHODS
16094	METHODS
16095	METHODS
16096	METHODS
16097	RESULTS
16098	RESULTS
16099	RESULTS
16100	RESULTS
16101	RESULTS
16102	RESULTS
16103	RESULTS
16104	RESULTS
16105	RESULTS
16106	BACKGROUND
16107	OBJECTIVE
16108	METHODS
16109	METHODS
16110	METHODS
16111	METHODS
16112	METHODS
16113	RESULTS
16114	RESULTS
16115	RESULTS
16116	RESULTS
16117	CONCLUSIONS
16118	CONCLUSIONS
16119	BACKGROUND
16120	OBJECTIVE
16121	OBJECTIVE
16122	METHODS
16123	METHODS
16124	METHODS
16125	METHODS
16126	METHODS
16127	RESULTS
16128	RESULTS
16129	RESULTS
16130	RESULTS
16131	RESULTS
16132	BACKGROUND
16133	CONCLUSIONS
16134	CONCLUSIONS
16135	OBJECTIVE
16136	BACKGROUND
16137	BACKGROUND
16138	METHODS
16139	METHODS
16140	METHODS
16141	METHODS
16142	RESULTS
16143	RESULTS
16144	RESULTS
16145	CONCLUSIONS
16146	CONCLUSIONS
16147	CONCLUSIONS
16148	OBJECTIVE
16149	METHODS
16150	METHODS
16151	CONCLUSIONS
16152	RESULTS
16153	RESULTS
16154	RESULTS
16155	RESULTS
16156	RESULTS
16157	RESULTS
16158	RESULTS
16159	BACKGROUND
16160	OBJECTIVE
16161	METHODS
16162	METHODS
16163	METHODS
16164	METHODS
16165	METHODS
16166	RESULTS
16167	RESULTS
16168	RESULTS
16169	RESULTS
16170	CONCLUSIONS
16171	OBJECTIVE
16172	METHODS
16173	METHODS
16174	RESULTS
16175	METHODS
16176	METHODS
16177	METHODS
16178	METHODS
16179	RESULTS
16180	RESULTS
16181	RESULTS
16182	RESULTS
16183	RESULTS
16184	RESULTS
16185	CONCLUSIONS
16186	BACKGROUND
16187	BACKGROUND
16188	METHODS
16189	METHODS
16190	METHODS
16191	RESULTS
16192	RESULTS
16193	CONCLUSIONS
16194	BACKGROUND
16195	BACKGROUND
16196	OBJECTIVE
16197	METHODS
16198	RESULTS
16199	RESULTS
16200	RESULTS
16201	CONCLUSIONS
16202	CONCLUSIONS
16203	CONCLUSIONS
16204	CONCLUSIONS
16205	OBJECTIVE
16206	METHODS
16207	METHODS
16208	METHODS
16209	METHODS
16210	METHODS
16211	RESULTS
16212	METHODS
16213	METHODS
16214	METHODS
16215	RESULTS
16216	RESULTS
16217	RESULTS
16218	RESULTS
16219	CONCLUSIONS
16220	BACKGROUND
16221	METHODS
16222	METHODS
16223	METHODS
16224	METHODS
16225	METHODS
16226	RESULTS
16227	RESULTS
16228	RESULTS
16229	RESULTS
16230	CONCLUSIONS
16231	RESULTS
16232	OBJECTIVE
16233	BACKGROUND
16234	OBJECTIVE
16235	METHODS
16236	METHODS
16237	METHODS
16238	METHODS
16239	METHODS
16240	RESULTS
16241	RESULTS
16242	RESULTS
16243	CONCLUSIONS
16244	CONCLUSIONS
16245	BACKGROUND
16246	BACKGROUND
16247	BACKGROUND
16248	BACKGROUND
16249	METHODS
16250	METHODS
16251	METHODS
16252	METHODS
16253	METHODS
16254	BACKGROUND
16255	BACKGROUND
16256	BACKGROUND
16257	BACKGROUND
16258	METHODS
16259	RESULTS
16260	RESULTS
16261	BACKGROUND
16262	METHODS
16263	METHODS
16264	METHODS
16265	METHODS
16266	METHODS
16267	RESULTS
16268	RESULTS
16269	RESULTS
16270	RESULTS
16271	CONCLUSIONS
16272	OBJECTIVE
16273	METHODS
16274	METHODS
16275	METHODS
16276	RESULTS
16277	RESULTS
16278	CONCLUSIONS
16279	CONCLUSIONS
16280	OBJECTIVE
16281	METHODS
16282	METHODS
16283	METHODS
16284	METHODS
16285	RESULTS
16286	RESULTS
16287	RESULTS
16288	RESULTS
16289	RESULTS
16290	RESULTS
16291	RESULTS
16292	RESULTS
16293	BACKGROUND
16294	RESULTS
16295	OBJECTIVE
16296	METHODS
16297	METHODS
16298	METHODS
16299	METHODS
16300	METHODS
16301	RESULTS
16302	RESULTS
16303	RESULTS
16304	RESULTS
16305	RESULTS
16306	CONCLUSIONS
16307	CONCLUSIONS
16308	BACKGROUND
16309	BACKGROUND
16310	OBJECTIVE
16311	METHODS
16312	RESULTS
16313	RESULTS
16314	CONCLUSIONS
16315	CONCLUSIONS
16316	OBJECTIVE
16317	METHODS
16318	METHODS
16319	METHODS
16320	METHODS
16321	RESULTS
16322	CONCLUSIONS
16323	CONCLUSIONS
16324	CONCLUSIONS
16325	BACKGROUND
16326	OBJECTIVE
16327	METHODS
16328	METHODS
16329	METHODS
16330	METHODS
16331	METHODS
16332	METHODS
16333	RESULTS
16334	RESULTS
16335	RESULTS
16336	RESULTS
16337	RESULTS
16338	CONCLUSIONS
16339	CONCLUSIONS
16340	RESULTS
16341	OBJECTIVE
16342	METHODS
16343	METHODS
16344	METHODS
16345	METHODS
16346	RESULTS
16347	RESULTS
16348	RESULTS
16349	RESULTS
16350	RESULTS
16351	RESULTS
16352	CONCLUSIONS
16353	CONCLUSIONS
16354	CONCLUSIONS
16355	CONCLUSIONS
16356	BACKGROUND
16357	CONCLUSIONS
16358	BACKGROUND
16359	METHODS
16360	METHODS
16361	METHODS
16362	RESULTS
16363	RESULTS
16364	RESULTS
16365	RESULTS
16366	RESULTS
16367	CONCLUSIONS
16368	BACKGROUND
16369	OBJECTIVE
16370	RESULTS
16371	CONCLUSIONS
16372	RESULTS
16373	CONCLUSIONS
16374	CONCLUSIONS
16375	BACKGROUND
16376	BACKGROUND
16377	BACKGROUND
16378	OBJECTIVE
16379	METHODS
16380	METHODS
16381	METHODS
16382	METHODS
16383	METHODS
16384	METHODS
16385	RESULTS
16386	RESULTS
16387	CONCLUSIONS
16388	OBJECTIVE
16389	METHODS
16390	METHODS
16391	METHODS
16392	METHODS
16393	METHODS
16394	METHODS
16395	RESULTS
16396	CONCLUSIONS
16397	CONCLUSIONS
16398	BACKGROUND
16399	OBJECTIVE
16400	METHODS
16401	METHODS
16402	METHODS
16403	CONCLUSIONS
16404	RESULTS
16405	CONCLUSIONS
16406	CONCLUSIONS
16407	OBJECTIVE
16408	METHODS
16409	RESULTS
16410	CONCLUSIONS
16411	RESULTS
16412	BACKGROUND
16413	BACKGROUND
16414	OBJECTIVE
16415	METHODS
16416	METHODS
16417	METHODS
16418	METHODS
16419	RESULTS
16420	RESULTS
16421	RESULTS
16422	RESULTS
16423	RESULTS
16424	RESULTS
16425	RESULTS
16426	RESULTS
16427	CONCLUSIONS
16428	RESULTS
16429	OBJECTIVE
16430	METHODS
16431	METHODS
16432	METHODS
16433	METHODS
16434	METHODS
16435	METHODS
16436	RESULTS
16437	RESULTS
16438	RESULTS
16439	RESULTS
16440	RESULTS
16441	CONCLUSIONS
16442	BACKGROUND
16443	OBJECTIVE
16444	METHODS
16445	METHODS
16446	RESULTS
16447	RESULTS
16448	RESULTS
16449	RESULTS
16450	RESULTS
16451	CONCLUSIONS
16452	CONCLUSIONS
16453	BACKGROUND
16454	OBJECTIVE
16455	METHODS
16456	METHODS
16457	METHODS
16458	METHODS
16459	METHODS
16460	METHODS
16461	RESULTS
16462	RESULTS
16463	RESULTS
16464	CONCLUSIONS
16465	OBJECTIVE
16466	METHODS
16467	METHODS
16468	METHODS
16469	RESULTS
16470	RESULTS
16471	RESULTS
16472	RESULTS
16473	RESULTS
16474	CONCLUSIONS
16475	CONCLUSIONS
16476	BACKGROUND
16477	BACKGROUND
16478	METHODS
16479	METHODS
16480	METHODS
16481	RESULTS
16482	RESULTS
16483	RESULTS
16484	RESULTS
16485	RESULTS
16486	CONCLUSIONS
16487	RESULTS
16488	CONCLUSIONS
16489	CONCLUSIONS
16490	OBJECTIVE
16491	METHODS
16492	METHODS
16493	RESULTS
16494	RESULTS
16495	CONCLUSIONS
16496	OBJECTIVE
16497	METHODS
16498	RESULTS
16499	RESULTS
16500	RESULTS
16501	RESULTS
16502	RESULTS
16503	CONCLUSIONS
16504	CONCLUSIONS
16505	OBJECTIVE
16506	METHODS
16507	METHODS
16508	METHODS
16509	METHODS
16510	RESULTS
16511	RESULTS
16512	RESULTS
16513	RESULTS
16514	CONCLUSIONS
16515	CONCLUSIONS
16516	BACKGROUND
16517	BACKGROUND
16518	OBJECTIVE
16519	METHODS
16520	METHODS
16521	METHODS
16522	RESULTS
16523	RESULTS
16524	CONCLUSIONS
16525	BACKGROUND
16526	BACKGROUND
16527	METHODS
16528	METHODS
16529	METHODS
16530	CONCLUSIONS
16531	METHODS
16532	CONCLUSIONS
16533	OBJECTIVE
16534	METHODS
16535	METHODS
16536	METHODS
16537	RESULTS
16538	RESULTS
16539	RESULTS
16540	CONCLUSIONS
16541	OBJECTIVE
16542	METHODS
16543	METHODS
16544	METHODS
16545	METHODS
16546	METHODS
16547	RESULTS
16548	METHODS
16549	RESULTS
16550	RESULTS
16551	RESULTS
16552	RESULTS
16553	CONCLUSIONS
16554	CONCLUSIONS
16555	OBJECTIVE
16556	METHODS
16557	METHODS
16558	METHODS
16559	METHODS
16560	METHODS
16561	METHODS
16562	METHODS
16563	RESULTS
16564	RESULTS
16565	RESULTS
16566	RESULTS
16567	RESULTS
16568	CONCLUSIONS
16569	OBJECTIVE
16570	METHODS
16571	RESULTS
16572	METHODS
16573	METHODS
16574	METHODS
16575	METHODS
16576	METHODS
16577	METHODS
16578	CONCLUSIONS
16579	RESULTS
16580	RESULTS
16581	RESULTS
16582	RESULTS
16583	CONCLUSIONS
16584	CONCLUSIONS
16585	CONCLUSIONS
16586	BACKGROUND
16587	METHODS
16588	METHODS
16589	METHODS
16590	RESULTS
16591	RESULTS
16592	RESULTS
16593	RESULTS
16594	CONCLUSIONS
16595	CONCLUSIONS
16596	BACKGROUND
16597	BACKGROUND
16598	BACKGROUND
16599	METHODS
16600	METHODS
16601	METHODS
16602	RESULTS
16603	RESULTS
16604	RESULTS
16605	RESULTS
16606	RESULTS
16607	RESULTS
16608	CONCLUSIONS
16609	CONCLUSIONS
16610	BACKGROUND
16611	BACKGROUND
16612	BACKGROUND
16613	OBJECTIVE
16614	METHODS
16615	METHODS
16616	METHODS
16617	METHODS
16618	METHODS
16619	METHODS
16620	METHODS
16621	RESULTS
16622	RESULTS
16623	RESULTS
16624	RESULTS
16625	CONCLUSIONS
16626	CONCLUSIONS
16627	BACKGROUND
16628	BACKGROUND
16629	METHODS
16630	METHODS
16631	METHODS
16632	RESULTS
16633	RESULTS
16634	RESULTS
16635	RESULTS
16636	OBJECTIVE
16637	METHODS
16638	METHODS
16639	METHODS
16640	METHODS
16641	METHODS
16642	METHODS
16643	METHODS
16644	RESULTS
16645	RESULTS
16646	RESULTS
16647	RESULTS
16648	RESULTS
16649	RESULTS
16650	CONCLUSIONS
16651	CONCLUSIONS
16652	OBJECTIVE
16653	METHODS
16654	METHODS
16655	METHODS
16656	METHODS
16657	METHODS
16658	METHODS
16659	RESULTS
16660	RESULTS
16661	RESULTS
16662	RESULTS
16663	RESULTS
16664	RESULTS
16665	RESULTS
16666	RESULTS
16667	CONCLUSIONS
16668	CONCLUSIONS
16669	BACKGROUND
16670	OBJECTIVE
16671	METHODS
16672	METHODS
16673	METHODS
16674	METHODS
16675	METHODS
16676	METHODS
16677	METHODS
16678	METHODS
16679	RESULTS
16680	RESULTS
16681	RESULTS
16682	CONCLUSIONS
16683	BACKGROUND
16684	BACKGROUND
16685	OBJECTIVE
16686	METHODS
16687	METHODS
16688	METHODS
16689	METHODS
16690	RESULTS
16691	RESULTS
16692	RESULTS
16693	RESULTS
16694	CONCLUSIONS
16695	CONCLUSIONS
16696	CONCLUSIONS
16697	BACKGROUND
16698	CONCLUSIONS
16699	BACKGROUND
16700	BACKGROUND
16701	METHODS
16702	METHODS
16703	RESULTS
16704	RESULTS
16705	RESULTS
16706	CONCLUSIONS
16707	CONCLUSIONS
16708	OBJECTIVE
16709	METHODS
16710	METHODS
16711	METHODS
16712	METHODS
16713	RESULTS
16714	RESULTS
16715	RESULTS
16716	RESULTS
16717	CONCLUSIONS
16718	CONCLUSIONS
16719	BACKGROUND
16720	OBJECTIVE
16721	METHODS
16722	METHODS
16723	METHODS
16724	RESULTS
16725	METHODS
16726	METHODS
16727	RESULTS
16728	RESULTS
16729	RESULTS
16730	RESULTS
16731	RESULTS
16732	RESULTS
16733	RESULTS
16734	RESULTS
16735	CONCLUSIONS
16736	CONCLUSIONS
16737	RESULTS
16738	BACKGROUND
16739	BACKGROUND
16740	METHODS
16741	METHODS
16742	METHODS
16743	METHODS
16744	METHODS
16745	METHODS
16746	RESULTS
16747	RESULTS
16748	RESULTS
16749	RESULTS
16750	RESULTS
16751	CONCLUSIONS
16752	BACKGROUND
16753	BACKGROUND
16754	METHODS
16755	METHODS
16756	RESULTS
16757	RESULTS
16758	RESULTS
16759	RESULTS
16760	RESULTS
16761	CONCLUSIONS
16762	CONCLUSIONS
16763	BACKGROUND
16764	BACKGROUND
16765	OBJECTIVE
16766	METHODS
16767	METHODS
16768	RESULTS
16769	RESULTS
16770	RESULTS
16771	CONCLUSIONS
16772	CONCLUSIONS
16773	BACKGROUND
16774	METHODS
16775	METHODS
16776	RESULTS
16777	RESULTS
16778	RESULTS
16779	RESULTS
16780	CONCLUSIONS
16781	METHODS
16782	BACKGROUND
16783	BACKGROUND
16784	OBJECTIVE
16785	METHODS
16786	METHODS
16787	METHODS
16788	RESULTS
16789	RESULTS
16790	RESULTS
16791	RESULTS
16792	RESULTS
16793	RESULTS
16794	RESULTS
16795	RESULTS
16796	CONCLUSIONS
16797	CONCLUSIONS
16798	BACKGROUND
16799	BACKGROUND
16800	BACKGROUND
16801	BACKGROUND
16802	OBJECTIVE
16803	BACKGROUND
16804	METHODS
16805	METHODS
16806	METHODS
16807	BACKGROUND
16808	METHODS
16809	METHODS
16810	METHODS
16811	METHODS
16812	METHODS
16813	BACKGROUND
16814	OBJECTIVE
16815	OBJECTIVE
16816	METHODS
16817	METHODS
16818	METHODS
16819	METHODS
16820	RESULTS
16821	RESULTS
16822	CONCLUSIONS
16823	CONCLUSIONS
16824	BACKGROUND
16825	OBJECTIVE
16826	METHODS
16827	METHODS
16828	METHODS
16829	METHODS
16830	METHODS
16831	METHODS
16832	RESULTS
16833	RESULTS
16834	RESULTS
16835	RESULTS
16836	RESULTS
16837	RESULTS
16838	RESULTS
16839	RESULTS
16840	CONCLUSIONS
16841	RESULTS
16842	BACKGROUND
16843	BACKGROUND
16844	METHODS
16845	METHODS
16846	METHODS
16847	RESULTS
16848	RESULTS
16849	CONCLUSIONS
16850	OBJECTIVE
16851	METHODS
16852	RESULTS
16853	METHODS
16854	METHODS
16855	METHODS
16856	METHODS
16857	METHODS
16858	RESULTS
16859	RESULTS
16860	CONCLUSIONS
16861	BACKGROUND
16862	BACKGROUND
16863	METHODS
16864	METHODS
16865	METHODS
16866	METHODS
16867	RESULTS
16868	RESULTS
16869	CONCLUSIONS
16870	BACKGROUND
16871	CONCLUSIONS
16872	BACKGROUND
16873	BACKGROUND
16874	OBJECTIVE
16875	METHODS
16876	METHODS
16877	METHODS
16878	RESULTS
16879	RESULTS
16880	CONCLUSIONS
16881	OBJECTIVE
16882	METHODS
16883	METHODS
16884	RESULTS
16885	METHODS
16886	METHODS
16887	METHODS
16888	METHODS
16889	METHODS
16890	RESULTS
16891	RESULTS
16892	RESULTS
16893	RESULTS
16894	RESULTS
16895	CONCLUSIONS
16896	CONCLUSIONS
16897	OBJECTIVE
16898	METHODS
16899	METHODS
16900	METHODS
16901	METHODS
16902	METHODS
16903	METHODS
16904	RESULTS
16905	RESULTS
16906	CONCLUSIONS
16907	CONCLUSIONS
16908	BACKGROUND
16909	BACKGROUND
16910	OBJECTIVE
16911	METHODS
16912	METHODS
16913	METHODS
16914	RESULTS
16915	RESULTS
16916	RESULTS
16917	CONCLUSIONS
16918	OBJECTIVE
16919	METHODS
16920	METHODS
16921	METHODS
16922	METHODS
16923	METHODS
16924	METHODS
16925	METHODS
16926	METHODS
16927	RESULTS
16928	RESULTS
16929	RESULTS
16930	CONCLUSIONS
16931	OBJECTIVE
16932	METHODS
16933	METHODS
16934	METHODS
16935	METHODS
16936	METHODS
16937	METHODS
16938	CONCLUSIONS
16939	RESULTS
16940	CONCLUSIONS
16941	BACKGROUND
16942	BACKGROUND
16943	BACKGROUND
16944	METHODS
16945	METHODS
16946	METHODS
16947	METHODS
16948	METHODS
16949	METHODS
16950	METHODS
16951	METHODS
16952	RESULTS
16953	RESULTS
16954	RESULTS
16955	RESULTS
16956	RESULTS
16957	RESULTS
16958	RESULTS
16959	RESULTS
16960	CONCLUSIONS
16961	CONCLUSIONS
16962	BACKGROUND
16963	OBJECTIVE
16964	METHODS
16965	METHODS
16966	RESULTS
16967	RESULTS
16968	CONCLUSIONS
16969	CONCLUSIONS
16970	BACKGROUND
16971	OBJECTIVE
16972	METHODS
16973	METHODS
16974	METHODS
16975	METHODS
16976	CONCLUSIONS
16977	RESULTS
16978	RESULTS
16979	RESULTS
16980	RESULTS
16981	RESULTS
16982	CONCLUSIONS
16983	CONCLUSIONS
16984	OBJECTIVE
16985	METHODS
16986	METHODS
16987	METHODS
16988	METHODS
16989	RESULTS
16990	RESULTS
16991	CONCLUSIONS
16992	OBJECTIVE
16993	OBJECTIVE
16994	METHODS
16995	METHODS
16996	METHODS
16997	METHODS
16998	METHODS
16999	METHODS
17000	METHODS
17001	METHODS
17002	RESULTS
17003	RESULTS
17004	RESULTS
17005	RESULTS
17006	CONCLUSIONS
17007	BACKGROUND
17008	METHODS
17009	METHODS
17010	METHODS
17011	METHODS
17012	RESULTS
17013	RESULTS
17014	CONCLUSIONS
17015	OBJECTIVE
17016	METHODS
17017	METHODS
17018	METHODS
17019	RESULTS
17020	METHODS
17021	RESULTS
17022	RESULTS
17023	RESULTS
17024	CONCLUSIONS
17025	CONCLUSIONS
17026	OBJECTIVE
17027	OBJECTIVE
17028	METHODS
17029	METHODS
17030	METHODS
17031	RESULTS
17032	RESULTS
17033	RESULTS
17034	RESULTS
17035	CONCLUSIONS
17036	CONCLUSIONS
17037	BACKGROUND
17038	METHODS
17039	METHODS
17040	RESULTS
17041	RESULTS
17042	RESULTS
17043	RESULTS
17044	CONCLUSIONS
17045	CONCLUSIONS
17046	RESULTS
17047	BACKGROUND
17048	BACKGROUND
17049	BACKGROUND
17050	BACKGROUND
17051	CONCLUSIONS
17052	METHODS
17053	METHODS
17054	RESULTS
17055	RESULTS
17056	RESULTS
17057	RESULTS
17058	RESULTS
17059	CONCLUSIONS
17060	CONCLUSIONS
17061	OBJECTIVE
17062	METHODS
17063	METHODS
17064	METHODS
17065	RESULTS
17066	RESULTS
17067	RESULTS
17068	RESULTS
17069	RESULTS
17070	RESULTS
17071	CONCLUSIONS
17072	RESULTS
17073	OBJECTIVE
17074	BACKGROUND
17075	OBJECTIVE
17076	METHODS
17077	METHODS
17078	METHODS
17079	RESULTS
17080	RESULTS
17081	RESULTS
17082	RESULTS
17083	CONCLUSIONS
17084	CONCLUSIONS
17085	OBJECTIVE
17086	OBJECTIVE
17087	OBJECTIVE
17088	METHODS
17089	METHODS
17090	METHODS
17091	RESULTS
17092	RESULTS
17093	CONCLUSIONS
17094	CONCLUSIONS
17095	OBJECTIVE
17096	METHODS
17097	METHODS
17098	METHODS
17099	METHODS
17100	RESULTS
17101	RESULTS
17102	RESULTS
17103	RESULTS
17104	RESULTS
17105	BACKGROUND
17106	CONCLUSIONS
17107	OBJECTIVE
17108	METHODS
17109	RESULTS
17110	RESULTS
17111	RESULTS
17112	RESULTS
17113	RESULTS
17114	CONCLUSIONS
17115	OBJECTIVE
17116	METHODS
17117	METHODS
17118	METHODS
17119	METHODS
17120	METHODS
17121	CONCLUSIONS
17122	METHODS
17123	OBJECTIVE
17124	CONCLUSIONS
17125	RESULTS
17126	RESULTS
17127	RESULTS
17128	RESULTS
17129	CONCLUSIONS
17130	CONCLUSIONS
17131	CONCLUSIONS
17132	BACKGROUND
17133	BACKGROUND
17134	OBJECTIVE
17135	METHODS
17136	METHODS
17137	RESULTS
17138	RESULTS
17139	RESULTS
17140	RESULTS
17141	RESULTS
17142	CONCLUSIONS
17143	CONCLUSIONS
17144	BACKGROUND
17145	BACKGROUND
17146	BACKGROUND
17147	BACKGROUND
17148	BACKGROUND
17149	METHODS
17150	METHODS
17151	RESULTS
17152	RESULTS
17153	CONCLUSIONS
17154	CONCLUSIONS
17155	BACKGROUND
17156	RESULTS
17157	CONCLUSIONS
17158	BACKGROUND
17159	METHODS
17160	METHODS
17161	METHODS
17162	METHODS
17163	METHODS
17164	METHODS
17165	METHODS
17166	METHODS
17167	METHODS
17168	CONCLUSIONS
17169	METHODS
17170	CONCLUSIONS
17171	BACKGROUND
17172	CONCLUSIONS
17173	OBJECTIVE
17174	METHODS
17175	METHODS
17176	METHODS
17177	CONCLUSIONS
17178	RESULTS
17179	RESULTS
17180	CONCLUSIONS
17181	RESULTS
17182	RESULTS
17183	RESULTS
17184	CONCLUSIONS
17185	CONCLUSIONS
17186	CONCLUSIONS
17187	OBJECTIVE
17188	METHODS
17189	METHODS
17190	METHODS
17191	METHODS
17192	METHODS
17193	METHODS
17194	RESULTS
17195	RESULTS
17196	RESULTS
17197	RESULTS
17198	CONCLUSIONS
17199	RESULTS
17200	RESULTS
17201	CONCLUSIONS
17202	OBJECTIVE
17203	METHODS
17204	METHODS
17205	METHODS
17206	METHODS
17207	METHODS
17208	METHODS
17209	METHODS
17210	RESULTS
17211	CONCLUSIONS
17212	BACKGROUND
17213	BACKGROUND
17214	OBJECTIVE
17215	METHODS
17216	METHODS
17217	METHODS
17218	METHODS
17219	METHODS
17220	RESULTS
17221	RESULTS
17222	CONCLUSIONS
17223	CONCLUSIONS
17224	OBJECTIVE
17225	METHODS
17226	METHODS
17227	METHODS
17228	RESULTS
17229	RESULTS
17230	METHODS
17231	CONCLUSIONS
17232	CONCLUSIONS
17233	OBJECTIVE
17234	METHODS
17235	METHODS
17236	RESULTS
17237	RESULTS
17238	RESULTS
17239	RESULTS
17240	RESULTS
17241	RESULTS
17242	CONCLUSIONS
17243	OBJECTIVE
17244	METHODS
17245	METHODS
17246	METHODS
17247	METHODS
17248	METHODS
17249	METHODS
17250	RESULTS
17251	RESULTS
17252	RESULTS
17253	CONCLUSIONS
17254	CONCLUSIONS
17255	BACKGROUND
17256	BACKGROUND
17257	METHODS
17258	RESULTS
17259	METHODS
17260	METHODS
17261	METHODS
17262	RESULTS
17263	RESULTS
17264	RESULTS
17265	RESULTS
17266	RESULTS
17267	CONCLUSIONS
17268	OBJECTIVE
17269	METHODS
17270	METHODS
17271	METHODS
17272	RESULTS
17273	RESULTS
17274	RESULTS
17275	RESULTS
17276	RESULTS
17277	RESULTS
17278	CONCLUSIONS
17279	CONCLUSIONS
17280	OBJECTIVE
17281	METHODS
17282	METHODS
17283	METHODS
17284	METHODS
17285	RESULTS
17286	RESULTS
17287	CONCLUSIONS
17288	CONCLUSIONS
17289	OBJECTIVE
17290	METHODS
17291	METHODS
17292	METHODS
17293	METHODS
17294	RESULTS
17295	RESULTS
17296	RESULTS
17297	CONCLUSIONS
17298	OBJECTIVE
17299	METHODS
17300	METHODS
17301	METHODS
17302	METHODS
17303	RESULTS
17304	RESULTS
17305	RESULTS
17306	RESULTS
17307	RESULTS
17308	RESULTS
17309	RESULTS
17310	BACKGROUND
17311	CONCLUSIONS
17312	BACKGROUND
17313	METHODS
17314	METHODS
17315	RESULTS
17316	RESULTS
17317	RESULTS
17318	RESULTS
17319	CONCLUSIONS
17320	CONCLUSIONS
17321	OBJECTIVE
17322	METHODS
17323	METHODS
17324	METHODS
17325	METHODS
17326	METHODS
17327	METHODS
17328	RESULTS
17329	RESULTS
17330	RESULTS
17331	RESULTS
17332	CONCLUSIONS
17333	BACKGROUND
17334	BACKGROUND
17335	METHODS
17336	METHODS
17337	METHODS
17338	RESULTS
17339	RESULTS
17340	CONCLUSIONS
17341	BACKGROUND
17342	CONCLUSIONS
17343	BACKGROUND
17344	BACKGROUND
17345	BACKGROUND
17346	METHODS
17347	METHODS
17348	METHODS
17349	METHODS
17350	RESULTS
17351	RESULTS
17352	RESULTS
17353	RESULTS
17354	CONCLUSIONS
17355	RESULTS
17356	BACKGROUND
17357	BACKGROUND
17358	OBJECTIVE
17359	METHODS
17360	METHODS
17361	METHODS
17362	RESULTS
17363	RESULTS
17364	RESULTS
17365	CONCLUSIONS
17366	OBJECTIVE
17367	METHODS
17368	METHODS
17369	METHODS
17370	RESULTS
17371	RESULTS
17372	RESULTS
17373	CONCLUSIONS
17374	CONCLUSIONS
17375	BACKGROUND
17376	BACKGROUND
17377	METHODS
17378	METHODS
17379	RESULTS
17380	RESULTS
17381	BACKGROUND
17382	BACKGROUND
17383	OBJECTIVE
17384	METHODS
17385	METHODS
17386	METHODS
17387	RESULTS
17388	RESULTS
17389	CONCLUSIONS
17390	OBJECTIVE
17391	METHODS
17392	METHODS
17393	METHODS
17394	METHODS
17395	RESULTS
17396	CONCLUSIONS
17397	CONCLUSIONS
17398	BACKGROUND
17399	BACKGROUND
17400	OBJECTIVE
17401	METHODS
17402	METHODS
17403	RESULTS
17404	RESULTS
17405	RESULTS
17406	RESULTS
17407	CONCLUSIONS
17408	OBJECTIVE
17409	METHODS
17410	METHODS
17411	METHODS
17412	METHODS
17413	RESULTS
17414	METHODS
17415	METHODS
17416	RESULTS
17417	RESULTS
17418	RESULTS
17419	CONCLUSIONS
17420	CONCLUSIONS
17421	BACKGROUND
17422	CONCLUSIONS
17423	OBJECTIVE
17424	METHODS
17425	METHODS
17426	METHODS
17427	METHODS
17428	METHODS
17429	METHODS
17430	METHODS
17431	METHODS
17432	METHODS
17433	RESULTS
17434	RESULTS
17435	RESULTS
17436	RESULTS
17437	CONCLUSIONS
17438	RESULTS
17439	BACKGROUND
17440	BACKGROUND
17441	METHODS
17442	METHODS
17443	RESULTS
17444	METHODS
17445	METHODS
17446	RESULTS
17447	RESULTS
17448	RESULTS
17449	RESULTS
17450	RESULTS
17451	CONCLUSIONS
17452	CONCLUSIONS
17453	CONCLUSIONS
17454	BACKGROUND
17455	BACKGROUND
17456	BACKGROUND
17457	METHODS
17458	RESULTS
17459	RESULTS
17460	RESULTS
17461	RESULTS
17462	CONCLUSIONS
17463	CONCLUSIONS
17464	CONCLUSIONS
17465	OBJECTIVE
17466	METHODS
17467	METHODS
17468	CONCLUSIONS
17469	RESULTS
17470	RESULTS
17471	BACKGROUND
17472	RESULTS
17473	OBJECTIVE
17474	METHODS
17475	METHODS
17476	METHODS
17477	METHODS
17478	METHODS
17479	METHODS
17480	METHODS
17481	METHODS
17482	METHODS
17483	RESULTS
17484	RESULTS
17485	RESULTS
17486	RESULTS
17487	RESULTS
17488	RESULTS
17489	CONCLUSIONS
17490	CONCLUSIONS
17491	CONCLUSIONS
17492	CONCLUSIONS
17493	BACKGROUND
17494	BACKGROUND
17495	BACKGROUND
17496	METHODS
17497	METHODS
17498	METHODS
17499	METHODS
17500	METHODS
17501	METHODS
17502	RESULTS
17503	RESULTS
17504	RESULTS
17505	RESULTS
17506	RESULTS
17507	RESULTS
17508	CONCLUSIONS
17509	CONCLUSIONS
17510	BACKGROUND
17511	CONCLUSIONS
17512	METHODS
17513	METHODS
17514	METHODS
17515	METHODS
17516	METHODS
17517	METHODS
17518	METHODS
17519	METHODS
17520	METHODS
17521	METHODS
17522	METHODS
17523	METHODS
17524	BACKGROUND
17525	BACKGROUND
17526	BACKGROUND
17527	CONCLUSIONS
17528	BACKGROUND
17529	BACKGROUND
17530	OBJECTIVE
17531	METHODS
17532	METHODS
17533	METHODS
17534	CONCLUSIONS
17535	RESULTS
17536	CONCLUSIONS
17537	CONCLUSIONS
17538	CONCLUSIONS
17539	CONCLUSIONS
17540	OBJECTIVE
17541	METHODS
17542	METHODS
17543	METHODS
17544	METHODS
17545	METHODS
17546	RESULTS
17547	RESULTS
17548	RESULTS
17549	CONCLUSIONS
17550	BACKGROUND
17551	BACKGROUND
17552	METHODS
17553	METHODS
17554	METHODS
17555	METHODS
17556	RESULTS
17557	CONCLUSIONS
17558	BACKGROUND
17559	BACKGROUND
17560	OBJECTIVE
17561	METHODS
17562	METHODS
17563	RESULTS
17564	RESULTS
17565	CONCLUSIONS
17566	OBJECTIVE
17567	METHODS
17568	METHODS
17569	METHODS
17570	METHODS
17571	METHODS
17572	RESULTS
17573	RESULTS
17574	RESULTS
17575	CONCLUSIONS
17576	BACKGROUND
17577	BACKGROUND
17578	METHODS
17579	METHODS
17580	METHODS
17581	METHODS
17582	RESULTS
17583	RESULTS
17584	RESULTS
17585	RESULTS
17586	RESULTS
17587	RESULTS
17588	RESULTS
17589	CONCLUSIONS
17590	BACKGROUND
17591	METHODS
17592	METHODS
17593	RESULTS
17594	RESULTS
17595	RESULTS
17596	CONCLUSIONS
17597	BACKGROUND
17598	BACKGROUND
17599	OBJECTIVE
17600	METHODS
17601	METHODS
17602	METHODS
17603	RESULTS
17604	RESULTS
17605	RESULTS
17606	RESULTS
17607	RESULTS
17608	CONCLUSIONS
17609	CONCLUSIONS
17610	CONCLUSIONS
17611	BACKGROUND
17612	OBJECTIVE
17613	METHODS
17614	METHODS
17615	METHODS
17616	METHODS
17617	RESULTS
17618	RESULTS
17619	RESULTS
17620	RESULTS
17621	RESULTS
17622	RESULTS
17623	CONCLUSIONS
17624	OBJECTIVE
17625	METHODS
17626	METHODS
17627	METHODS
17628	RESULTS
17629	RESULTS
17630	RESULTS
17631	RESULTS
17632	RESULTS
17633	RESULTS
17634	RESULTS
17635	RESULTS
17636	CONCLUSIONS
17637	OBJECTIVE
17638	METHODS
17639	METHODS
17640	METHODS
17641	METHODS
17642	METHODS
17643	METHODS
17644	METHODS
17645	RESULTS
17646	RESULTS
17647	RESULTS
17648	RESULTS
17649	CONCLUSIONS
17650	BACKGROUND
17651	BACKGROUND
17652	BACKGROUND
17653	BACKGROUND
17654	METHODS
17655	METHODS
17656	METHODS
17657	METHODS
17658	METHODS
17659	CONCLUSIONS
17660	BACKGROUND
17661	BACKGROUND
17662	METHODS
17663	METHODS
17664	METHODS
17665	METHODS
17666	RESULTS
17667	RESULTS
17668	RESULTS
17669	RESULTS
17670	CONCLUSIONS
17671	RESULTS
17672	CONCLUSIONS
17673	BACKGROUND
17674	RESULTS
17675	METHODS
17676	METHODS
17677	RESULTS
17678	RESULTS
17679	RESULTS
17680	BACKGROUND
17681	CONCLUSIONS
17682	BACKGROUND
17683	OBJECTIVE
17684	METHODS
17685	METHODS
17686	METHODS
17687	RESULTS
17688	RESULTS
17689	RESULTS
17690	CONCLUSIONS
17691	CONCLUSIONS
17692	BACKGROUND
17693	BACKGROUND
17694	OBJECTIVE
17695	RESULTS
17696	METHODS
17697	METHODS
17698	RESULTS
17699	RESULTS
17700	RESULTS
17701	CONCLUSIONS
17702	CONCLUSIONS
17703	OBJECTIVE
17704	METHODS
17705	METHODS
17706	RESULTS
17707	CONCLUSIONS
17708	BACKGROUND
17709	BACKGROUND
17710	METHODS
17711	METHODS
17712	RESULTS
17713	RESULTS
17714	RESULTS
17715	RESULTS
17716	RESULTS
17717	CONCLUSIONS
17718	CONCLUSIONS
17719	BACKGROUND
17720	BACKGROUND
17721	BACKGROUND
17722	BACKGROUND
17723	BACKGROUND
17724	METHODS
17725	METHODS
17726	METHODS
17727	METHODS
17728	METHODS
17729	METHODS
17730	BACKGROUND
17731	CONCLUSIONS
17732	BACKGROUND
17733	BACKGROUND
17734	OBJECTIVE
17735	METHODS
17736	METHODS
17737	RESULTS
17738	RESULTS
17739	RESULTS
17740	RESULTS
17741	CONCLUSIONS
17742	BACKGROUND
17743	METHODS
17744	RESULTS
17745	RESULTS
17746	RESULTS
17747	RESULTS
17748	RESULTS
17749	CONCLUSIONS
17750	CONCLUSIONS
17751	OBJECTIVE
17752	METHODS
17753	RESULTS
17754	RESULTS
17755	RESULTS
17756	RESULTS
17757	RESULTS
17758	CONCLUSIONS
17759	BACKGROUND
17760	METHODS
17761	METHODS
17762	BACKGROUND
17763	METHODS
17764	METHODS
17765	METHODS
17766	METHODS
17767	METHODS
17768	METHODS
17769	CONCLUSIONS
17770	CONCLUSIONS
17771	BACKGROUND
17772	BACKGROUND
17773	OBJECTIVE
17774	OBJECTIVE
17775	METHODS
17776	METHODS
17777	METHODS
17778	METHODS
17779	RESULTS
17780	RESULTS
17781	RESULTS
17782	RESULTS
17783	CONCLUSIONS
17784	CONCLUSIONS
17785	BACKGROUND
17786	METHODS
17787	METHODS
17788	METHODS
17789	METHODS
17790	METHODS
17791	RESULTS
17792	RESULTS
17793	RESULTS
17794	RESULTS
17795	CONCLUSIONS
17796	OBJECTIVE
17797	METHODS
17798	METHODS
17799	RESULTS
17800	METHODS
17801	RESULTS
17802	METHODS
17803	METHODS
17804	METHODS
17805	RESULTS
17806	RESULTS
17807	RESULTS
17808	RESULTS
17809	RESULTS
17810	CONCLUSIONS
17811	CONCLUSIONS
17812	OBJECTIVE
17813	METHODS
17814	METHODS
17815	RESULTS
17816	RESULTS
17817	BACKGROUND
17818	BACKGROUND
17819	OBJECTIVE
17820	METHODS
17821	METHODS
17822	METHODS
17823	METHODS
17824	METHODS
17825	RESULTS
17826	RESULTS
17827	RESULTS
17828	RESULTS
17829	RESULTS
17830	CONCLUSIONS
17831	CONCLUSIONS
17832	BACKGROUND
17833	BACKGROUND
17834	OBJECTIVE
17835	METHODS
17836	METHODS
17837	RESULTS
17838	RESULTS
17839	CONCLUSIONS
17840	BACKGROUND
17841	CONCLUSIONS
17842	CONCLUSIONS
17843	BACKGROUND
17844	BACKGROUND
17845	BACKGROUND
17846	METHODS
17847	METHODS
17848	METHODS
17849	METHODS
17850	METHODS
17851	RESULTS
17852	RESULTS
17853	RESULTS
17854	CONCLUSIONS
17855	CONCLUSIONS
17856	CONCLUSIONS
17857	OBJECTIVE
17858	METHODS
17859	METHODS
17860	METHODS
17861	METHODS
17862	METHODS
17863	METHODS
17864	RESULTS
17865	RESULTS
17866	CONCLUSIONS
17867	OBJECTIVE
17868	METHODS
17869	METHODS
17870	METHODS
17871	METHODS
17872	RESULTS
17873	RESULTS
17874	RESULTS
17875	RESULTS
17876	CONCLUSIONS
17877	OBJECTIVE
17878	OBJECTIVE
17879	METHODS
17880	METHODS
17881	METHODS
17882	METHODS
17883	METHODS
17884	METHODS
17885	METHODS
17886	RESULTS
17887	RESULTS
17888	RESULTS
17889	RESULTS
17890	RESULTS
17891	RESULTS
17892	RESULTS
17893	RESULTS
17894	RESULTS
17895	CONCLUSIONS
17896	CONCLUSIONS
17897	OBJECTIVE
17898	METHODS
17899	METHODS
17900	METHODS
17901	METHODS
17902	METHODS
17903	METHODS
17904	RESULTS
17905	RESULTS
17906	RESULTS
17907	RESULTS
17908	RESULTS
17909	RESULTS
17910	RESULTS
17911	CONCLUSIONS
17912	BACKGROUND
17913	METHODS
17914	OBJECTIVE
17915	RESULTS
17916	RESULTS
17917	RESULTS
17918	CONCLUSIONS
17919	OBJECTIVE
17920	METHODS
17921	BACKGROUND
17922	CONCLUSIONS
17923	METHODS
17924	RESULTS
17925	RESULTS
17926	RESULTS
17927	CONCLUSIONS
17928	RESULTS
17929	RESULTS
17930	RESULTS
17931	RESULTS
17932	CONCLUSIONS
17933	CONCLUSIONS
17934	OBJECTIVE
17935	OBJECTIVE
17936	METHODS
17937	METHODS
17938	METHODS
17939	RESULTS
17940	RESULTS
17941	RESULTS
17942	RESULTS
17943	CONCLUSIONS
17944	BACKGROUND
17945	BACKGROUND
17946	BACKGROUND
17947	METHODS
17948	METHODS
17949	METHODS
17950	METHODS
17951	RESULTS
17952	RESULTS
17953	RESULTS
17954	RESULTS
17955	CONCLUSIONS
17956	BACKGROUND
17957	BACKGROUND
17958	OBJECTIVE
17959	METHODS
17960	METHODS
17961	CONCLUSIONS
17962	CONCLUSIONS
17963	CONCLUSIONS
17964	BACKGROUND
17965	BACKGROUND
17966	BACKGROUND
17967	METHODS
17968	METHODS
17969	METHODS
17970	METHODS
17971	RESULTS
17972	RESULTS
17973	RESULTS
17974	RESULTS
17975	CONCLUSIONS
17976	CONCLUSIONS
17977	BACKGROUND
17978	CONCLUSIONS
17979	OBJECTIVE
17980	METHODS
17981	METHODS
17982	RESULTS
17983	RESULTS
17984	RESULTS
17985	RESULTS
17986	OBJECTIVE
17987	METHODS
17988	METHODS
17989	METHODS
17990	METHODS
17991	RESULTS
17992	RESULTS
17993	RESULTS
17994	RESULTS
17995	RESULTS
17996	CONCLUSIONS
17997	OBJECTIVE
17998	METHODS
17999	METHODS
18000	METHODS
18001	METHODS
18002	RESULTS
18003	RESULTS
18004	RESULTS
18005	RESULTS
18006	CONCLUSIONS
18007	CONCLUSIONS
18008	CONCLUSIONS
18009	BACKGROUND
18010	OBJECTIVE
18011	OBJECTIVE
18012	METHODS
18013	METHODS
18014	METHODS
18015	METHODS
18016	RESULTS
18017	RESULTS
18018	CONCLUSIONS
18019	BACKGROUND
18020	BACKGROUND
18021	OBJECTIVE
18022	METHODS
18023	METHODS
18024	METHODS
18025	METHODS
18026	RESULTS
18027	RESULTS
18028	CONCLUSIONS
18029	CONCLUSIONS
18030	OBJECTIVE
18031	METHODS
18032	METHODS
18033	METHODS
18034	METHODS
18035	METHODS
18036	RESULTS
18037	CONCLUSIONS
18038	OBJECTIVE
18039	METHODS
18040	METHODS
18041	METHODS
18042	METHODS
18043	METHODS
18044	RESULTS
18045	RESULTS
18046	CONCLUSIONS
18047	CONCLUSIONS
18048	BACKGROUND
18049	METHODS
18050	METHODS
18051	METHODS
18052	METHODS
18053	METHODS
18054	METHODS
18055	METHODS
18056	RESULTS
18057	RESULTS
18058	RESULTS
18059	RESULTS
18060	CONCLUSIONS
18061	BACKGROUND
18062	BACKGROUND
18063	OBJECTIVE
18064	METHODS
18065	METHODS
18066	METHODS
18067	RESULTS
18068	RESULTS
18069	RESULTS
18070	RESULTS
18071	CONCLUSIONS
18072	OBJECTIVE
18073	METHODS
18074	METHODS
18075	RESULTS
18076	RESULTS
18077	RESULTS
18078	RESULTS
18079	RESULTS
18080	RESULTS
18081	CONCLUSIONS
18082	CONCLUSIONS
18083	OBJECTIVE
18084	BACKGROUND
18085	BACKGROUND
18086	RESULTS
18087	RESULTS
18088	METHODS
18089	METHODS
18090	RESULTS
18091	RESULTS
18092	RESULTS
18093	RESULTS
18094	RESULTS
18095	RESULTS
18096	CONCLUSIONS
18097	BACKGROUND
18098	BACKGROUND
18099	BACKGROUND
18100	BACKGROUND
18101	METHODS
18102	METHODS
18103	METHODS
18104	OBJECTIVE
18105	OBJECTIVE
18106	RESULTS
18107	RESULTS
18108	CONCLUSIONS
18109	CONCLUSIONS
18110	BACKGROUND
18111	OBJECTIVE
18112	METHODS
18113	RESULTS
18114	RESULTS
18115	RESULTS
18116	RESULTS
18117	CONCLUSIONS
18118	BACKGROUND
18119	BACKGROUND
18120	OBJECTIVE
18121	METHODS
18122	METHODS
18123	RESULTS
18124	RESULTS
18125	CONCLUSIONS
18126	CONCLUSIONS
18127	OBJECTIVE
18128	METHODS
18129	METHODS
18130	METHODS
18131	METHODS
18132	METHODS
18133	METHODS
18134	RESULTS
18135	RESULTS
18136	RESULTS
18137	RESULTS
18138	RESULTS
18139	CONCLUSIONS
18140	RESULTS
18141	RESULTS
18142	CONCLUSIONS
18143	CONCLUSIONS
18144	BACKGROUND
18145	OBJECTIVE
18146	METHODS
18147	METHODS
18148	METHODS
18149	METHODS
18150	METHODS
18151	METHODS
18152	METHODS
18153	RESULTS
18154	RESULTS
18155	CONCLUSIONS
18156	OBJECTIVE
18157	METHODS
18158	METHODS
18159	METHODS
18160	METHODS
18161	METHODS
18162	RESULTS
18163	RESULTS
18164	RESULTS
18165	RESULTS
18166	RESULTS
18167	CONCLUSIONS
18168	BACKGROUND
18169	OBJECTIVE
18170	METHODS
18171	METHODS
18172	METHODS
18173	RESULTS
18174	RESULTS
18175	RESULTS
18176	RESULTS
18177	CONCLUSIONS
18178	OBJECTIVE
18179	METHODS
18180	METHODS
18181	METHODS
18182	METHODS
18183	METHODS
18184	METHODS
18185	RESULTS
18186	RESULTS
18187	RESULTS
18188	RESULTS
18189	RESULTS
18190	RESULTS
18191	RESULTS
18192	RESULTS
18193	CONCLUSIONS
18194	OBJECTIVE
18195	METHODS
18196	METHODS
18197	METHODS
18198	RESULTS
18199	RESULTS
18200	RESULTS
18201	RESULTS
18202	RESULTS
18203	CONCLUSIONS
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18205	CONCLUSIONS
18206	BACKGROUND
18207	BACKGROUND
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18212	BACKGROUND
18213	OBJECTIVE
18214	METHODS
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18224	OBJECTIVE
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18233	OBJECTIVE
18234	BACKGROUND
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18236	METHODS
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18243	BACKGROUND
18244	OBJECTIVE
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18254	OBJECTIVE
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18263	OBJECTIVE
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18276	OBJECTIVE
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18296	CONCLUSIONS
18297	BACKGROUND
18298	METHODS
18299	METHODS
18300	METHODS
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18309	OBJECTIVE
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18311	METHODS
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18313	METHODS
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18317	CONCLUSIONS
18318	RESULTS
18319	OBJECTIVE
18320	METHODS
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18325	BACKGROUND
18326	OBJECTIVE
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18330	RESULTS
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18332	RESULTS
18333	OBJECTIVE
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18340	RESULTS
18341	CONCLUSIONS
18342	OBJECTIVE
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18352	BACKGROUND
18353	OBJECTIVE
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18363	BACKGROUND
18364	BACKGROUND
18365	BACKGROUND
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18368	METHODS
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18383	OBJECTIVE
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18393	RESULTS
18394	RESULTS
18395	RESULTS
18396	RESULTS
18397	RESULTS
18398	CONCLUSIONS
18399	CONCLUSIONS
18400	CONCLUSIONS
18401	BACKGROUND
18402	BACKGROUND
18403	BACKGROUND
18404	OBJECTIVE
18405	METHODS
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18410	RESULTS
18411	RESULTS
18412	RESULTS
18413	RESULTS
18414	RESULTS
18415	RESULTS
18416	RESULTS
18417	RESULTS
18418	CONCLUSIONS
18419	CONCLUSIONS
18420	OBJECTIVE
18421	METHODS
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18423	METHODS
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18430	BACKGROUND
18431	METHODS
18432	METHODS
18433	RESULTS
18434	RESULTS
18435	CONCLUSIONS
18436	RESULTS
18437	RESULTS
18438	CONCLUSIONS
18439	CONCLUSIONS
18440	RESULTS
18441	BACKGROUND
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18443	METHODS
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18446	RESULTS
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18450	RESULTS
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18452	CONCLUSIONS
18453	BACKGROUND
18454	CONCLUSIONS
18455	BACKGROUND
18456	OBJECTIVE
18457	METHODS
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18460	RESULTS
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18464	BACKGROUND
18465	BACKGROUND
18466	BACKGROUND
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18468	METHODS
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18471	RESULTS
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18476	CONCLUSIONS
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18478	OBJECTIVE
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18480	METHODS
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18486	RESULTS
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18488	CONCLUSIONS
18489	BACKGROUND
18490	BACKGROUND
18491	CONCLUSIONS
18492	BACKGROUND
18493	METHODS
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18497	CONCLUSIONS
18498	CONCLUSIONS
18499	BACKGROUND
18500	BACKGROUND
18501	BACKGROUND
18502	OBJECTIVE
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18504	METHODS
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18510	CONCLUSIONS
18511	OBJECTIVE
18512	METHODS
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18514	METHODS
18515	RESULTS
18516	RESULTS
18517	RESULTS
18518	RESULTS
18519	CONCLUSIONS
18520	RESULTS
18521	BACKGROUND
18522	BACKGROUND
18523	OBJECTIVE
18524	METHODS
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18527	RESULTS
18528	RESULTS
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18530	CONCLUSIONS
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18532	BACKGROUND
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18534	METHODS
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18539	RESULTS
18540	RESULTS
18541	RESULTS
18542	RESULTS
18543	RESULTS
18544	RESULTS
18545	CONCLUSIONS
18546	RESULTS
18547	CONCLUSIONS
18548	BACKGROUND
18549	BACKGROUND
18550	OBJECTIVE
18551	METHODS
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18560	RESULTS
18561	RESULTS
18562	CONCLUSIONS
18563	BACKGROUND
18564	BACKGROUND
18565	METHODS
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18567	RESULTS
18568	RESULTS
18569	RESULTS
18570	RESULTS
18571	RESULTS
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18573	RESULTS
18574	RESULTS
18575	RESULTS
18576	CONCLUSIONS
18577	OBJECTIVE
18578	METHODS
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18580	METHODS
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18583	RESULTS
18584	RESULTS
18585	RESULTS
18586	RESULTS
18587	CONCLUSIONS
18588	OBJECTIVE
18589	METHODS
18590	METHODS
18591	METHODS
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18593	METHODS
18594	METHODS
18595	METHODS
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18597	RESULTS
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18599	RESULTS
18600	CONCLUSIONS
18601	CONCLUSIONS
18602	OBJECTIVE
18603	METHODS
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18607	RESULTS
18608	CONCLUSIONS
18609	BACKGROUND
18610	CONCLUSIONS
18611	METHODS
18612	METHODS
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18617	RESULTS
18618	BACKGROUND
18619	RESULTS
18620	BACKGROUND
18621	CONCLUSIONS
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18623	BACKGROUND
18624	OBJECTIVE
18625	METHODS
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18631	CONCLUSIONS
18632	CONCLUSIONS
18633	BACKGROUND
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18635	OBJECTIVE
18636	METHODS
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18640	RESULTS
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18643	BACKGROUND
18644	OBJECTIVE
18645	METHODS
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18650	RESULTS
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18656	CONCLUSIONS
18657	BACKGROUND
18658	CONCLUSIONS
18659	OBJECTIVE
18660	METHODS
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18664	RESULTS
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18667	RESULTS
18668	OBJECTIVE
18669	METHODS
18670	METHODS
18671	METHODS
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18675	RESULTS
18676	CONCLUSIONS
18677	BACKGROUND
18678	OBJECTIVE
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18680	METHODS
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18685	RESULTS
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18687	RESULTS
18688	RESULTS
18689	CONCLUSIONS
18690	BACKGROUND
18691	CONCLUSIONS
18692	OBJECTIVE
18693	METHODS
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18695	RESULTS
18696	RESULTS
18697	RESULTS
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18699	CONCLUSIONS
18700	BACKGROUND
18701	BACKGROUND
18702	OBJECTIVE
18703	METHODS
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18705	METHODS
18706	METHODS
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18710	RESULTS
18711	RESULTS
18712	RESULTS
18713	CONCLUSIONS
18714	CONCLUSIONS
18715	BACKGROUND
18716	OBJECTIVE
18717	METHODS
18718	METHODS
18719	METHODS
18720	METHODS
18721	RESULTS
18722	RESULTS
18723	RESULTS
18724	CONCLUSIONS
18725	RESULTS
18726	CONCLUSIONS
18727	OBJECTIVE
18728	METHODS
18729	METHODS
18730	RESULTS
18731	RESULTS
18732	RESULTS
18733	CONCLUSIONS
18734	CONCLUSIONS
18735	OBJECTIVE
18736	METHODS
18737	METHODS
18738	METHODS
18739	METHODS
18740	METHODS
18741	RESULTS
18742	RESULTS
18743	RESULTS
18744	RESULTS
18745	RESULTS
18746	RESULTS
18747	CONCLUSIONS
18748	BACKGROUND
18749	BACKGROUND
18750	OBJECTIVE
18751	METHODS
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18756	RESULTS
18757	RESULTS
18758	RESULTS
18759	RESULTS
18760	CONCLUSIONS
18761	RESULTS
18762	RESULTS
18763	OBJECTIVE
18764	METHODS
18765	METHODS
18766	RESULTS
18767	RESULTS
18768	RESULTS
18769	RESULTS
18770	RESULTS
18771	RESULTS
18772	RESULTS
18773	RESULTS
18774	CONCLUSIONS
18775	OBJECTIVE
18776	METHODS
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18778	METHODS
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18780	METHODS
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18784	RESULTS
18785	CONCLUSIONS
18786	BACKGROUND
18787	BACKGROUND
18788	OBJECTIVE
18789	METHODS
18790	METHODS
18791	RESULTS
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18793	RESULTS
18794	RESULTS
18795	RESULTS
18796	CONCLUSIONS
18797	CONCLUSIONS
18798	BACKGROUND
18799	OBJECTIVE
18800	METHODS
18801	METHODS
18802	METHODS
18803	METHODS
18804	METHODS
18805	RESULTS
18806	RESULTS
18807	RESULTS
18808	CONCLUSIONS
18809	CONCLUSIONS
18810	METHODS
18811	OBJECTIVE
18812	METHODS
18813	METHODS
18814	METHODS
18815	RESULTS
18816	RESULTS
18817	RESULTS
18818	CONCLUSIONS
18819	OBJECTIVE
18820	METHODS
18821	METHODS
18822	RESULTS
18823	RESULTS
18824	CONCLUSIONS
18825	CONCLUSIONS
18826	OBJECTIVE
18827	METHODS
18828	METHODS
18829	METHODS
18830	METHODS
18831	METHODS
18832	METHODS
18833	RESULTS
18834	RESULTS
18835	RESULTS
18836	CONCLUSIONS
18837	RESULTS
18838	BACKGROUND
18839	BACKGROUND
18840	BACKGROUND
18841	METHODS
18842	RESULTS
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18844	RESULTS
18845	RESULTS
18846	RESULTS
18847	RESULTS
18848	RESULTS
18849	CONCLUSIONS
18850	CONCLUSIONS
18851	BACKGROUND
18852	OBJECTIVE
18853	METHODS
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18859	RESULTS
18860	RESULTS
18861	RESULTS
18862	RESULTS
18863	CONCLUSIONS
18864	RESULTS
18865	CONCLUSIONS
18866	BACKGROUND
18867	BACKGROUND
18868	BACKGROUND
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18870	METHODS
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18876	BACKGROUND
18877	BACKGROUND
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18880	METHODS
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18884	RESULTS
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18886	RESULTS
18887	RESULTS
18888	CONCLUSIONS
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18890	BACKGROUND
18891	METHODS
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18898	RESULTS
18899	CONCLUSIONS
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18901	BACKGROUND
18902	CONCLUSIONS
18903	OBJECTIVE
18904	METHODS
18905	METHODS
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18907	METHODS
18908	RESULTS
18909	RESULTS
18910	RESULTS
18911	RESULTS
18912	RESULTS
18913	RESULTS
18914	RESULTS
18915	RESULTS
18916	RESULTS
18917	CONCLUSIONS
18918	BACKGROUND
18919	BACKGROUND
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18921	METHODS
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18924	METHODS
18925	RESULTS
18926	RESULTS
18927	RESULTS
18928	RESULTS
18929	RESULTS
18930	CONCLUSIONS
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18932	BACKGROUND
18933	BACKGROUND
18934	METHODS
18935	METHODS
18936	METHODS
18937	RESULTS
18938	RESULTS
18939	RESULTS
18940	RESULTS
18941	CONCLUSIONS
18942	OBJECTIVE
18943	METHODS
18944	METHODS
18945	METHODS
18946	RESULTS
18947	RESULTS
18948	RESULTS
18949	RESULTS
18950	RESULTS
18951	RESULTS
18952	CONCLUSIONS
18953	OBJECTIVE
18954	METHODS
18955	METHODS
18956	METHODS
18957	METHODS
18958	RESULTS
18959	RESULTS
18960	RESULTS
18961	RESULTS
18962	RESULTS
18963	CONCLUSIONS
18964	OBJECTIVE
18965	OBJECTIVE
18966	METHODS
18967	METHODS
18968	METHODS
18969	METHODS
18970	METHODS
18971	METHODS
18972	METHODS
18973	RESULTS
18974	RESULTS
18975	RESULTS
18976	RESULTS
18977	RESULTS
18978	CONCLUSIONS
18979	OBJECTIVE
18980	METHODS
18981	RESULTS
18982	RESULTS
18983	CONCLUSIONS
18984	BACKGROUND
18985	BACKGROUND
18986	METHODS
18987	METHODS
18988	RESULTS
18989	RESULTS
18990	CONCLUSIONS
18991	OBJECTIVE
18992	OBJECTIVE
18993	RESULTS
18994	RESULTS
18995	RESULTS
18996	RESULTS
18997	RESULTS
18998	CONCLUSIONS
18999	CONCLUSIONS
19000	OBJECTIVE
19001	METHODS
19002	METHODS
19003	METHODS
19004	METHODS
19005	METHODS
19006	RESULTS
19007	RESULTS
19008	RESULTS
19009	RESULTS
19010	CONCLUSIONS
19011	BACKGROUND
19012	BACKGROUND
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19014	METHODS
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19016	METHODS
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19019	METHODS
19020	RESULTS
19021	RESULTS
19022	RESULTS
19023	RESULTS
19024	RESULTS
19025	CONCLUSIONS
19026	RESULTS
19027	RESULTS
19028	BACKGROUND
19029	OBJECTIVE
19030	METHODS
19031	METHODS
19032	METHODS
19033	METHODS
19034	METHODS
19035	RESULTS
19036	RESULTS
19037	RESULTS
19038	RESULTS
19039	RESULTS
19040	CONCLUSIONS
19041	BACKGROUND
19042	BACKGROUND
19043	OBJECTIVE
19044	METHODS
19045	METHODS
19046	METHODS
19047	METHODS
19048	METHODS
19049	RESULTS
19050	RESULTS
19051	RESULTS
19052	RESULTS
19053	RESULTS
19054	RESULTS
19055	RESULTS
19056	RESULTS
19057	RESULTS
19058	RESULTS
19059	CONCLUSIONS
19060	RESULTS
19061	CONCLUSIONS
19062	BACKGROUND
19063	OBJECTIVE
19064	METHODS
19065	METHODS
19066	RESULTS
19067	CONCLUSIONS
19068	RESULTS
19069	CONCLUSIONS
19070	CONCLUSIONS
19071	CONCLUSIONS
19072	OBJECTIVE
19073	METHODS
19074	METHODS
19075	RESULTS
19076	RESULTS
19077	RESULTS
19078	RESULTS
19079	RESULTS
19080	CONCLUSIONS
19081	RESULTS
19082	OBJECTIVE
19083	METHODS
19084	METHODS
19085	METHODS
19086	RESULTS
19087	RESULTS
19088	RESULTS
19089	RESULTS
19090	CONCLUSIONS
19091	BACKGROUND
19092	BACKGROUND
19093	OBJECTIVE
19094	METHODS
19095	METHODS
19096	METHODS
19097	RESULTS
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19099	RESULTS
19100	CONCLUSIONS
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19102	OBJECTIVE
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19104	METHODS
19105	METHODS
19106	METHODS
19107	METHODS
19108	RESULTS
19109	RESULTS
19110	RESULTS
19111	RESULTS
19112	RESULTS
19113	RESULTS
19114	RESULTS
19115	RESULTS
19116	RESULTS
19117	CONCLUSIONS
19118	RESULTS
19119	CONCLUSIONS
19120	OBJECTIVE
19121	METHODS
19122	METHODS
19123	METHODS
19124	RESULTS
19125	RESULTS
19126	RESULTS
19127	CONCLUSIONS
19128	OBJECTIVE
19129	BACKGROUND
19130	BACKGROUND
19131	METHODS
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19134	METHODS
19135	RESULTS
19136	RESULTS
19137	CONCLUSIONS
19138	CONCLUSIONS
19139	CONCLUSIONS
19140	CONCLUSIONS
19141	CONCLUSIONS
19142	BACKGROUND
19143	BACKGROUND
19144	OBJECTIVE
19145	METHODS
19146	OBJECTIVE
19147	METHODS
19148	RESULTS
19149	RESULTS
19150	RESULTS
19151	RESULTS
19152	RESULTS
19153	CONCLUSIONS
19154	BACKGROUND
19155	METHODS
19156	METHODS
19157	RESULTS
19158	RESULTS
19159	RESULTS
19160	CONCLUSIONS
19161	RESULTS
19162	BACKGROUND
19163	BACKGROUND
19164	CONCLUSIONS
19165	OBJECTIVE
19166	METHODS
19167	METHODS
19168	METHODS
19169	METHODS
19170	RESULTS
19171	RESULTS
19172	RESULTS
19173	RESULTS
19174	CONCLUSIONS
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19176	OBJECTIVE
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19178	METHODS
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19180	METHODS
19181	METHODS
19182	RESULTS
19183	RESULTS
19184	RESULTS
19185	METHODS
19186	RESULTS
19187	RESULTS
19188	RESULTS
19189	RESULTS
19190	CONCLUSIONS
19191	OBJECTIVE
19192	METHODS
19193	METHODS
19194	RESULTS
19195	RESULTS
19196	RESULTS
19197	RESULTS
19198	RESULTS
19199	CONCLUSIONS
19200	CONCLUSIONS
19201	CONCLUSIONS
19202	BACKGROUND
19203	BACKGROUND
19204	BACKGROUND
19205	BACKGROUND
19206	OBJECTIVE
19207	METHODS
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19210	METHODS
19211	METHODS
19212	CONCLUSIONS
19213	BACKGROUND
19214	BACKGROUND
19215	OBJECTIVE
19216	METHODS
19217	METHODS
19218	METHODS
19219	METHODS
19220	METHODS
19221	METHODS
19222	RESULTS
19223	RESULTS
19224	RESULTS
19225	RESULTS
19226	RESULTS
19227	CONCLUSIONS
19228	CONCLUSIONS
19229	OBJECTIVE
19230	METHODS
19231	METHODS
19232	METHODS
19233	RESULTS
19234	RESULTS
19235	RESULTS
19236	RESULTS
19237	RESULTS
19238	RESULTS
19239	RESULTS
19240	RESULTS
19241	RESULTS
19242	RESULTS
19243	BACKGROUND
19244	CONCLUSIONS
19245	BACKGROUND
19246	OBJECTIVE
19247	METHODS
19248	METHODS
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19250	METHODS
19251	METHODS
19252	METHODS
19253	CONCLUSIONS
19254	BACKGROUND
19255	OBJECTIVE
19256	METHODS
19257	RESULTS
19258	RESULTS
19259	RESULTS
19260	RESULTS
19261	RESULTS
19262	CONCLUSIONS
19263	OBJECTIVE
19264	METHODS
19265	RESULTS
19266	RESULTS
19267	RESULTS
19268	RESULTS
19269	RESULTS
19270	CONCLUSIONS
19271	BACKGROUND
19272	OBJECTIVE
19273	METHODS
19274	METHODS
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19280	RESULTS
19281	RESULTS
19282	RESULTS
19283	CONCLUSIONS
19284	OBJECTIVE
19285	METHODS
19286	METHODS
19287	METHODS
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19289	METHODS
19290	RESULTS
19291	RESULTS
19292	RESULTS
19293	CONCLUSIONS
19294	BACKGROUND
19295	BACKGROUND
19296	METHODS
19297	METHODS
19298	METHODS
19299	METHODS
19300	METHODS
19301	RESULTS
19302	RESULTS
19303	RESULTS
19304	RESULTS
19305	RESULTS
19306	RESULTS
19307	BACKGROUND
19308	BACKGROUND
19309	OBJECTIVE
19310	METHODS
19311	METHODS
19312	METHODS
19313	METHODS
19314	METHODS
19315	METHODS
19316	METHODS
19317	RESULTS
19318	RESULTS
19319	CONCLUSIONS
19320	OBJECTIVE
19321	METHODS
19322	METHODS
19323	METHODS
19324	METHODS
19325	RESULTS
19326	METHODS
19327	RESULTS
19328	RESULTS
19329	RESULTS
19330	RESULTS
19331	RESULTS
19332	RESULTS
19333	RESULTS
19334	CONCLUSIONS
19335	METHODS
19336	OBJECTIVE
19337	METHODS
19338	METHODS
19339	METHODS
19340	RESULTS
19341	RESULTS
19342	RESULTS
19343	RESULTS
19344	CONCLUSIONS
19345	OBJECTIVE
19346	OBJECTIVE
19347	METHODS
19348	METHODS
19349	RESULTS
19350	METHODS
19351	RESULTS
19352	CONCLUSIONS
19353	RESULTS
19354	RESULTS
19355	CONCLUSIONS
19356	BACKGROUND
19357	OBJECTIVE
19358	OBJECTIVE
19359	METHODS
19360	METHODS
19361	RESULTS
19362	RESULTS
19363	RESULTS
19364	CONCLUSIONS
19365	BACKGROUND
19366	BACKGROUND
19367	OBJECTIVE
19368	METHODS
19369	METHODS
19370	RESULTS
19371	RESULTS
19372	RESULTS
19373	RESULTS
19374	RESULTS
19375	RESULTS
19376	CONCLUSIONS
19377	CONCLUSIONS
19378	OBJECTIVE
19379	METHODS
19380	METHODS
19381	RESULTS
19382	RESULTS
19383	CONCLUSIONS
19384	BACKGROUND
19385	METHODS
19386	METHODS
19387	METHODS
19388	RESULTS
19389	RESULTS
19390	CONCLUSIONS
19391	BACKGROUND
19392	OBJECTIVE
19393	METHODS
19394	METHODS
19395	METHODS
19396	METHODS
19397	RESULTS
19398	RESULTS
19399	RESULTS
19400	RESULTS
19401	RESULTS
19402	RESULTS
19403	CONCLUSIONS
19404	BACKGROUND
19405	BACKGROUND
19406	OBJECTIVE
19407	CONCLUSIONS
19408	METHODS
19409	METHODS
19410	RESULTS
19411	METHODS
19412	OBJECTIVE
19413	METHODS
19414	METHODS
19415	METHODS
19416	METHODS
19417	RESULTS
19418	RESULTS
19419	RESULTS
19420	RESULTS
19421	RESULTS
19422	RESULTS
19423	RESULTS
19424	RESULTS
19425	CONCLUSIONS
19426	CONCLUSIONS
19427	BACKGROUND
19428	BACKGROUND
19429	METHODS
19430	METHODS
19431	METHODS
19432	RESULTS
19433	RESULTS
19434	RESULTS
19435	CONCLUSIONS
19436	CONCLUSIONS
19437	OBJECTIVE
19438	OBJECTIVE
19439	METHODS
19440	METHODS
19441	RESULTS
19442	RESULTS
19443	RESULTS
19444	CONCLUSIONS
19445	BACKGROUND
19446	BACKGROUND
19447	OBJECTIVE
19448	METHODS
19449	METHODS
19450	METHODS
19451	METHODS
19452	METHODS
19453	RESULTS
19454	RESULTS
19455	RESULTS
19456	RESULTS
19457	RESULTS
19458	BACKGROUND
19459	BACKGROUND
19460	BACKGROUND
19461	METHODS
19462	METHODS
19463	METHODS
19464	METHODS
19465	RESULTS
19466	CONCLUSIONS
19467	BACKGROUND
19468	BACKGROUND
19469	BACKGROUND
19470	METHODS
19471	METHODS
19472	METHODS
19473	METHODS
19474	RESULTS
19475	RESULTS
19476	RESULTS
19477	CONCLUSIONS
19478	CONCLUSIONS
19479	BACKGROUND
19480	BACKGROUND
19481	METHODS
19482	METHODS
19483	METHODS
19484	METHODS
19485	METHODS
19486	METHODS
19487	RESULTS
19488	RESULTS
19489	CONCLUSIONS
19490	OBJECTIVE
19491	METHODS
19492	METHODS
19493	METHODS
19494	METHODS
19495	METHODS
19496	RESULTS
19497	METHODS
19498	RESULTS
19499	RESULTS
19500	CONCLUSIONS
19501	BACKGROUND
19502	RESULTS
19503	RESULTS
19504	RESULTS
19505	CONCLUSIONS
19506	BACKGROUND
19507	OBJECTIVE
19508	METHODS
19509	METHODS
19510	METHODS
19511	METHODS
19512	METHODS
19513	RESULTS
19514	RESULTS
19515	RESULTS
19516	RESULTS
19517	CONCLUSIONS
19518	BACKGROUND
19519	BACKGROUND
19520	METHODS
19521	METHODS
19522	METHODS
19523	RESULTS
19524	RESULTS
19525	CONCLUSIONS
19526	CONCLUSIONS
19527	BACKGROUND
19528	BACKGROUND
19529	METHODS
19530	METHODS
19531	RESULTS
19532	RESULTS
19533	RESULTS
19534	RESULTS
19535	CONCLUSIONS
19536	OBJECTIVE
19537	BACKGROUND
19538	OBJECTIVE
19539	RESULTS
19540	RESULTS
19541	METHODS
19542	RESULTS
19543	RESULTS
19544	CONCLUSIONS
19545	CONCLUSIONS
19546	CONCLUSIONS
19547	CONCLUSIONS
19548	BACKGROUND
19549	CONCLUSIONS
19550	BACKGROUND
19551	OBJECTIVE
19552	METHODS
19553	METHODS
19554	METHODS
19555	METHODS
19556	METHODS
19557	RESULTS
19558	RESULTS
19559	RESULTS
19560	RESULTS
19561	CONCLUSIONS
19562	OBJECTIVE
19563	METHODS
19564	METHODS
19565	METHODS
19566	METHODS
19567	METHODS
19568	METHODS
19569	RESULTS
19570	RESULTS
19571	CONCLUSIONS
19572	CONCLUSIONS
19573	OBJECTIVE
19574	METHODS
19575	METHODS
19576	METHODS
19577	RESULTS
19578	RESULTS
19579	RESULTS
19580	RESULTS
19581	RESULTS
19582	RESULTS
19583	RESULTS
19584	CONCLUSIONS
19585	RESULTS
19586	CONCLUSIONS
19587	BACKGROUND
19588	OBJECTIVE
19589	METHODS
19590	RESULTS
19591	METHODS
19592	RESULTS
19593	RESULTS
19594	RESULTS
19595	CONCLUSIONS
19596	OBJECTIVE
19597	METHODS
19598	METHODS
19599	METHODS
19600	METHODS
19601	METHODS
19602	METHODS
19603	RESULTS
19604	RESULTS
19605	RESULTS
19606	RESULTS
19607	RESULTS
19608	RESULTS
19609	CONCLUSIONS
19610	OBJECTIVE
19611	METHODS
19612	METHODS
19613	METHODS
19614	METHODS
19615	RESULTS
19616	RESULTS
19617	RESULTS
19618	CONCLUSIONS
19619	RESULTS
19620	BACKGROUND
19621	BACKGROUND
19622	METHODS
19623	METHODS
19624	METHODS
19625	METHODS
19626	RESULTS
19627	RESULTS
19628	CONCLUSIONS
19629	RESULTS
19630	CONCLUSIONS
19631	CONCLUSIONS
19632	OBJECTIVE
19633	METHODS
19634	METHODS
19635	METHODS
19636	METHODS
19637	METHODS
19638	RESULTS
19639	RESULTS
19640	RESULTS
19641	RESULTS
19642	BACKGROUND
19643	CONCLUSIONS
19644	CONCLUSIONS
19645	CONCLUSIONS
19646	OBJECTIVE
19647	METHODS
19648	METHODS
19649	METHODS
19650	RESULTS
19651	RESULTS
19652	RESULTS
19653	CONCLUSIONS
19654	OBJECTIVE
19655	METHODS
19656	METHODS
19657	METHODS
19658	METHODS
19659	RESULTS
19660	RESULTS
19661	RESULTS
19662	RESULTS
19663	RESULTS
19664	RESULTS
19665	RESULTS
19666	CONCLUSIONS
19667	CONCLUSIONS
19668	OBJECTIVE
19669	METHODS
19670	METHODS
19671	RESULTS
19672	RESULTS
19673	RESULTS
19674	RESULTS
19675	RESULTS
19676	CONCLUSIONS
19677	BACKGROUND
19678	CONCLUSIONS
19679	OBJECTIVE
19680	METHODS
19681	RESULTS
19682	RESULTS
19683	RESULTS
19684	CONCLUSIONS
19685	BACKGROUND
19686	BACKGROUND
19687	METHODS
19688	METHODS
19689	METHODS
19690	RESULTS
19691	RESULTS
19692	CONCLUSIONS
19693	BACKGROUND
19694	BACKGROUND
19695	OBJECTIVE
19696	METHODS
19697	METHODS
19698	RESULTS
19699	RESULTS
19700	RESULTS
19701	RESULTS
19702	CONCLUSIONS
19703	OBJECTIVE
19704	METHODS
19705	METHODS
19706	METHODS
19707	RESULTS
19708	RESULTS
19709	RESULTS
19710	RESULTS
19711	RESULTS
19712	RESULTS
19713	RESULTS
19714	CONCLUSIONS
19715	CONCLUSIONS
19716	CONCLUSIONS
19717	OBJECTIVE
19718	OBJECTIVE
19719	BACKGROUND
19720	METHODS
19721	METHODS
19722	METHODS
19723	METHODS
19724	METHODS
19725	METHODS
19726	METHODS
19727	METHODS
19728	METHODS
19729	METHODS
19730	METHODS
19731	METHODS
19732	CONCLUSIONS
19733	BACKGROUND
19734	OBJECTIVE
19735	METHODS
19736	METHODS
19737	METHODS
19738	METHODS
19739	METHODS
19740	METHODS
19741	METHODS
19742	METHODS
19743	RESULTS
19744	RESULTS
19745	RESULTS
19746	RESULTS
19747	RESULTS
19748	RESULTS
19749	RESULTS
19750	CONCLUSIONS
19751	OBJECTIVE
19752	METHODS
19753	METHODS
19754	METHODS
19755	RESULTS
19756	METHODS
19757	METHODS
19758	RESULTS
19759	RESULTS
19760	RESULTS
19761	RESULTS
19762	CONCLUSIONS
19763	BACKGROUND
19764	BACKGROUND
19765	CONCLUSIONS
19766	CONCLUSIONS
19767	BACKGROUND
19768	METHODS
19769	METHODS
19770	METHODS
19771	METHODS
19772	RESULTS
19773	RESULTS
19774	RESULTS
19775	METHODS
19776	RESULTS
19777	RESULTS
19778	RESULTS
19779	RESULTS
19780	BACKGROUND
19781	CONCLUSIONS
19782	CONCLUSIONS
19783	BACKGROUND
19784	OBJECTIVE
19785	METHODS
19786	METHODS
19787	RESULTS
19788	RESULTS
19789	RESULTS
19790	CONCLUSIONS
19791	OBJECTIVE
19792	METHODS
19793	METHODS
19794	METHODS
19795	METHODS
19796	METHODS
19797	RESULTS
19798	RESULTS
19799	RESULTS
19800	RESULTS
19801	RESULTS
19802	CONCLUSIONS
19803	CONCLUSIONS
19804	BACKGROUND
19805	BACKGROUND
19806	OBJECTIVE
19807	METHODS
19808	METHODS
19809	METHODS
19810	RESULTS
19811	METHODS
19812	METHODS
19813	METHODS
19814	METHODS
19815	RESULTS
19816	CONCLUSIONS
19817	METHODS
19818	OBJECTIVE
19819	METHODS
19820	METHODS
19821	METHODS
19822	METHODS
19823	METHODS
19824	METHODS
19825	RESULTS
19826	RESULTS
19827	RESULTS
19828	CONCLUSIONS
19829	BACKGROUND
19830	METHODS
19831	METHODS
19832	RESULTS
19833	RESULTS
19834	RESULTS
19835	RESULTS
19836	CONCLUSIONS
19837	CONCLUSIONS
19838	OBJECTIVE
19839	METHODS
19840	METHODS
19841	METHODS
19842	METHODS
19843	METHODS
19844	METHODS
19845	RESULTS
19846	RESULTS
19847	RESULTS
19848	RESULTS
19849	CONCLUSIONS
19850	CONCLUSIONS
19851	BACKGROUND
19852	OBJECTIVE
19853	OBJECTIVE
19854	METHODS
19855	METHODS
19856	RESULTS
19857	RESULTS
19858	CONCLUSIONS
19859	OBJECTIVE
19860	METHODS
19861	METHODS
19862	RESULTS
19863	RESULTS
19864	RESULTS
19865	RESULTS
19866	RESULTS
19867	CONCLUSIONS
19868	OBJECTIVE
19869	METHODS
19870	METHODS
19871	CONCLUSIONS
19872	RESULTS
19873	CONCLUSIONS
19874	OBJECTIVE
19875	BACKGROUND
19876	BACKGROUND
19877	OBJECTIVE
19878	METHODS
19879	METHODS
19880	RESULTS
19881	RESULTS
19882	CONCLUSIONS
19883	RESULTS
19884	RESULTS
19885	CONCLUSIONS
19886	CONCLUSIONS
19887	OBJECTIVE
19888	OBJECTIVE
19889	METHODS
19890	RESULTS
19891	RESULTS
19892	CONCLUSIONS
19893	CONCLUSIONS
19894	CONCLUSIONS
19895	BACKGROUND
19896	BACKGROUND
19897	BACKGROUND
19898	OBJECTIVE
19899	METHODS
19900	METHODS
19901	METHODS
19902	METHODS
19903	RESULTS
19904	RESULTS
19905	RESULTS
19906	RESULTS
19907	CONCLUSIONS
19908	RESULTS
19909	RESULTS
19910	BACKGROUND
19911	BACKGROUND
19912	OBJECTIVE
19913	METHODS
19914	METHODS
19915	METHODS
19916	RESULTS
19917	RESULTS
19918	CONCLUSIONS
19919	CONCLUSIONS
19920	OBJECTIVE
19921	METHODS
19922	METHODS
19923	METHODS
19924	RESULTS
19925	METHODS
19926	METHODS
19927	METHODS
19928	RESULTS
19929	RESULTS
19930	RESULTS
19931	RESULTS
19932	CONCLUSIONS
19933	BACKGROUND
19934	CONCLUSIONS
19935	BACKGROUND
19936	METHODS
19937	METHODS
19938	METHODS
19939	METHODS
19940	METHODS
19941	RESULTS
19942	RESULTS
19943	RESULTS
19944	RESULTS
19945	CONCLUSIONS
19946	CONCLUSIONS
19947	OBJECTIVE
19948	METHODS
19949	METHODS
19950	METHODS
19951	METHODS
19952	RESULTS
19953	RESULTS
19954	CONCLUSIONS
19955	RESULTS
19956	OBJECTIVE
19957	METHODS
19958	METHODS
19959	METHODS
19960	METHODS
19961	METHODS
19962	METHODS
19963	RESULTS
19964	RESULTS
19965	CONCLUSIONS
19966	OBJECTIVE
19967	METHODS
19968	METHODS
19969	METHODS
19970	RESULTS
19971	RESULTS
19972	RESULTS
19973	CONCLUSIONS
19974	BACKGROUND
19975	BACKGROUND
19976	CONCLUSIONS
19977	OBJECTIVE
19978	BACKGROUND
19979	METHODS
19980	METHODS
19981	METHODS
19982	METHODS
19983	METHODS
19984	METHODS
19985	METHODS
19986	METHODS
19987	METHODS
19988	CONCLUSIONS
19989	CONCLUSIONS
19990	BACKGROUND
19991	OBJECTIVE
19992	RESULTS
19993	METHODS
19994	METHODS
19995	METHODS
19996	RESULTS
19997	RESULTS
19998	RESULTS
19999	RESULTS
20000	RESULTS
20001	CONCLUSIONS
20002	OBJECTIVE
20003	METHODS
20004	METHODS
20005	METHODS
20006	METHODS
20007	RESULTS
20008	RESULTS
20009	RESULTS
20010	RESULTS
20011	CONCLUSIONS
20012	OBJECTIVE
20013	CONCLUSIONS
20014	METHODS
20015	METHODS
20016	RESULTS
20017	RESULTS
20018	RESULTS
20019	RESULTS
20020	RESULTS
20021	RESULTS
20022	CONCLUSIONS
20023	CONCLUSIONS
20024	BACKGROUND
20025	RESULTS
20026	BACKGROUND
20027	BACKGROUND
20028	METHODS
20029	METHODS
20030	METHODS
20031	METHODS
20032	RESULTS
20033	RESULTS
20034	RESULTS
20035	RESULTS
20036	CONCLUSIONS
20037	CONCLUSIONS
20038	OBJECTIVE
20039	METHODS
20040	METHODS
20041	METHODS
20042	METHODS
20043	METHODS
20044	METHODS
20045	RESULTS
20046	RESULTS
20047	RESULTS
20048	RESULTS
20049	RESULTS
20050	RESULTS
20051	BACKGROUND
20052	BACKGROUND
20053	CONCLUSIONS
20054	BACKGROUND
20055	METHODS
20056	RESULTS
20057	RESULTS
20058	RESULTS
20059	CONCLUSIONS
20060	CONCLUSIONS
20061	BACKGROUND
20062	CONCLUSIONS
20063	METHODS
20064	METHODS
20065	METHODS
20066	RESULTS
20067	RESULTS
20068	RESULTS
20069	RESULTS
20070	RESULTS
20071	CONCLUSIONS
20072	BACKGROUND
20073	BACKGROUND
20074	OBJECTIVE
20075	METHODS
20076	METHODS
20077	METHODS
20078	METHODS
20079	RESULTS
20080	RESULTS
20081	RESULTS
20082	RESULTS
20083	RESULTS
20084	CONCLUSIONS
20085	OBJECTIVE
20086	METHODS
20087	METHODS
20088	METHODS
20089	RESULTS
20090	RESULTS
20091	RESULTS
20092	CONCLUSIONS
20093	BACKGROUND
20094	BACKGROUND
20095	BACKGROUND
20096	METHODS
20097	METHODS
20098	METHODS
20099	RESULTS
20100	RESULTS
20101	RESULTS
20102	RESULTS
20103	RESULTS
20104	RESULTS
20105	BACKGROUND
20106	OBJECTIVE
20107	METHODS
20108	METHODS
20109	METHODS
20110	METHODS
20111	RESULTS
20112	RESULTS
20113	RESULTS
20114	BACKGROUND
20115	CONCLUSIONS
20116	BACKGROUND
20117	OBJECTIVE
20118	METHODS
20119	METHODS
20120	METHODS
20121	METHODS
20122	METHODS
20123	RESULTS
20124	RESULTS
20125	RESULTS
20126	RESULTS
20127	CONCLUSIONS
20128	CONCLUSIONS
20129	RESULTS
20130	CONCLUSIONS
20131	BACKGROUND
20132	METHODS
20133	METHODS
20134	METHODS
20135	METHODS
20136	RESULTS
20137	RESULTS
20138	RESULTS
20139	RESULTS
20140	RESULTS
20141	CONCLUSIONS
20142	CONCLUSIONS
20143	BACKGROUND
20144	OBJECTIVE
20145	METHODS
20146	METHODS
20147	METHODS
20148	METHODS
20149	METHODS
20150	METHODS
20151	METHODS
20152	RESULTS
20153	RESULTS
20154	RESULTS
20155	RESULTS
20156	CONCLUSIONS
20157	BACKGROUND
20158	METHODS
20159	METHODS
20160	METHODS
20161	METHODS
20162	METHODS
20163	METHODS
20164	METHODS
20165	RESULTS
20166	RESULTS
20167	RESULTS
20168	CONCLUSIONS
20169	BACKGROUND
20170	BACKGROUND
20171	OBJECTIVE
20172	METHODS
20173	METHODS
20174	CONCLUSIONS
20175	RESULTS
20176	CONCLUSIONS
20177	BACKGROUND
20178	BACKGROUND
20179	BACKGROUND
20180	METHODS
20181	METHODS
20182	RESULTS
20183	RESULTS
20184	RESULTS
20185	RESULTS
20186	RESULTS
20187	RESULTS
20188	CONCLUSIONS
20189	RESULTS
20190	BACKGROUND
20191	METHODS
20192	METHODS
20193	METHODS
20194	METHODS
20195	METHODS
20196	OBJECTIVE
20197	RESULTS
20198	RESULTS
20199	CONCLUSIONS
20200	BACKGROUND
20201	OBJECTIVE
20202	METHODS
20203	METHODS
20204	METHODS
20205	METHODS
20206	RESULTS
20207	RESULTS
20208	RESULTS
20209	RESULTS
20210	RESULTS
20211	CONCLUSIONS
20212	CONCLUSIONS
20213	BACKGROUND
20214	BACKGROUND
20215	BACKGROUND
20216	BACKGROUND
20217	BACKGROUND
20218	METHODS
20219	METHODS
20220	METHODS
20221	RESULTS
20222	RESULTS
20223	RESULTS
20224	CONCLUSIONS
20225	OBJECTIVE
20226	BACKGROUND
20227	METHODS
20228	METHODS
20229	RESULTS
20230	RESULTS
20231	RESULTS
20232	RESULTS
20233	CONCLUSIONS
20234	CONCLUSIONS
20235	OBJECTIVE
20236	BACKGROUND
20237	METHODS
20238	METHODS
20239	RESULTS
20240	RESULTS
20241	CONCLUSIONS
20242	RESULTS
20243	CONCLUSIONS
20244	CONCLUSIONS
20245	CONCLUSIONS
20246	BACKGROUND
20247	BACKGROUND
20248	METHODS
20249	METHODS
20250	METHODS
20251	METHODS
20252	RESULTS
20253	RESULTS
20254	RESULTS
20255	RESULTS
20256	CONCLUSIONS
20257	BACKGROUND
20258	BACKGROUND
20259	METHODS
20260	RESULTS
20261	METHODS
20262	METHODS
20263	CONCLUSIONS
20264	CONCLUSIONS
20265	CONCLUSIONS
20266	CONCLUSIONS
20267	CONCLUSIONS
20268	OBJECTIVE
20269	METHODS
20270	METHODS
20271	METHODS
20272	METHODS
20273	METHODS
20274	RESULTS
20275	RESULTS
20276	RESULTS
20277	CONCLUSIONS
20278	OBJECTIVE
20279	METHODS
20280	RESULTS
20281	RESULTS
20282	RESULTS
20283	RESULTS
20284	CONCLUSIONS
20285	CONCLUSIONS
20286	OBJECTIVE
20287	CONCLUSIONS
20288	BACKGROUND
20289	BACKGROUND
20290	RESULTS
20291	RESULTS
20292	RESULTS
20293	RESULTS
20294	RESULTS
20295	CONCLUSIONS
20296	OBJECTIVE
20297	BACKGROUND
20298	BACKGROUND
20299	METHODS
20300	METHODS
20301	METHODS
20302	METHODS
20303	RESULTS
20304	RESULTS
20305	RESULTS
20306	RESULTS
20307	RESULTS
20308	CONCLUSIONS
20309	CONCLUSIONS
20310	OBJECTIVE
20311	METHODS
20312	METHODS
20313	METHODS
20314	METHODS
20315	METHODS
20316	METHODS
20317	METHODS
20318	RESULTS
20319	RESULTS
20320	RESULTS
20321	CONCLUSIONS
20322	CONCLUSIONS
20323	CONCLUSIONS
20324	OBJECTIVE
20325	METHODS
20326	METHODS
20327	METHODS
20328	METHODS
20329	METHODS
20330	RESULTS
20331	RESULTS
20332	RESULTS
20333	METHODS
20334	CONCLUSIONS
20335	BACKGROUND
20336	OBJECTIVE
20337	METHODS
20338	METHODS
20339	METHODS
20340	METHODS
20341	METHODS
20342	RESULTS
20343	RESULTS
20344	CONCLUSIONS
20345	CONCLUSIONS
20346	METHODS
20347	BACKGROUND
20348	METHODS
20349	METHODS
20350	METHODS
20351	METHODS
20352	METHODS
20353	METHODS
20354	RESULTS
20355	RESULTS
20356	RESULTS
20357	CONCLUSIONS
20358	CONCLUSIONS
20359	BACKGROUND
20360	METHODS
20361	METHODS
20362	METHODS
20363	METHODS
20364	METHODS
20365	RESULTS
20366	RESULTS
20367	CONCLUSIONS
20368	OBJECTIVE
20369	BACKGROUND
20370	METHODS
20371	METHODS
20372	METHODS
20373	METHODS
20374	RESULTS
20375	RESULTS
20376	RESULTS
20377	RESULTS
20378	CONCLUSIONS
20379	CONCLUSIONS
20380	OBJECTIVE
20381	METHODS
20382	METHODS
20383	METHODS
20384	METHODS
20385	METHODS
20386	RESULTS
20387	RESULTS
20388	RESULTS
20389	CONCLUSIONS
20390	OBJECTIVE
20391	METHODS
20392	METHODS
20393	METHODS
20394	METHODS
20395	METHODS
20396	METHODS
20397	METHODS
20398	METHODS
20399	RESULTS
20400	RESULTS
20401	CONCLUSIONS
20402	BACKGROUND
20403	OBJECTIVE
20404	BACKGROUND
20405	METHODS
20406	METHODS
20407	RESULTS
20408	RESULTS
20409	RESULTS
20410	RESULTS
20411	RESULTS
20412	CONCLUSIONS
20413	BACKGROUND
20414	BACKGROUND
20415	OBJECTIVE
20416	METHODS
20417	METHODS
20418	METHODS
20419	METHODS
20420	RESULTS
20421	RESULTS
20422	CONCLUSIONS
20423	CONCLUSIONS
20424	OBJECTIVE
20425	METHODS
20426	METHODS
20427	METHODS
20428	METHODS
20429	METHODS
20430	METHODS
20431	RESULTS
20432	RESULTS
20433	RESULTS
20434	RESULTS
20435	RESULTS
20436	CONCLUSIONS
20437	BACKGROUND
20438	CONCLUSIONS
20439	OBJECTIVE
20440	RESULTS
20441	RESULTS
20442	RESULTS
20443	RESULTS
20444	CONCLUSIONS
20445	CONCLUSIONS
20446	BACKGROUND
20447	BACKGROUND
20448	METHODS
20449	METHODS
20450	RESULTS
20451	RESULTS
20452	RESULTS
20453	CONCLUSIONS
20454	CONCLUSIONS
20455	OBJECTIVE
20456	METHODS
20457	METHODS
20458	METHODS
20459	RESULTS
20460	RESULTS
20461	CONCLUSIONS
20462	CONCLUSIONS
20463	CONCLUSIONS
20464	CONCLUSIONS
20465	BACKGROUND
20466	BACKGROUND
20467	OBJECTIVE
20468	METHODS
20469	RESULTS
20470	RESULTS
20471	RESULTS
20472	CONCLUSIONS
20473	RESULTS
20474	BACKGROUND
20475	BACKGROUND
20476	METHODS
20477	METHODS
20478	METHODS
20479	RESULTS
20480	RESULTS
20481	RESULTS
20482	RESULTS
20483	RESULTS
20484	RESULTS
20485	RESULTS
20486	RESULTS
20487	CONCLUSIONS
20488	CONCLUSIONS
20489	RESULTS
20490	BACKGROUND
20491	OBJECTIVE
20492	METHODS
20493	METHODS
20494	METHODS
20495	METHODS
20496	METHODS
20497	RESULTS
20498	RESULTS
20499	RESULTS
20500	RESULTS
20501	RESULTS
20502	CONCLUSIONS
20503	BACKGROUND
20504	OBJECTIVE
20505	CONCLUSIONS
20506	OBJECTIVE
20507	METHODS
20508	METHODS
20509	METHODS
20510	RESULTS
20511	RESULTS
20512	RESULTS
20513	CONCLUSIONS
20514	CONCLUSIONS
20515	BACKGROUND
20516	BACKGROUND
20517	METHODS
20518	METHODS
20519	METHODS
20520	METHODS
20521	RESULTS
20522	RESULTS
20523	RESULTS
20524	RESULTS
20525	RESULTS
20526	CONCLUSIONS
20527	CONCLUSIONS
20528	BACKGROUND
20529	OBJECTIVE
20530	METHODS
20531	METHODS
20532	METHODS
20533	RESULTS
20534	RESULTS
20535	CONCLUSIONS
20536	CONCLUSIONS
20537	BACKGROUND
20538	OBJECTIVE
20539	METHODS
20540	METHODS
20541	METHODS
20542	RESULTS
20543	RESULTS
20544	RESULTS
20545	CONCLUSIONS
20546	CONCLUSIONS
20547	BACKGROUND
20548	BACKGROUND
20549	METHODS
20550	METHODS
20551	CONCLUSIONS
20552	RESULTS
20553	RESULTS
20554	RESULTS
20555	CONCLUSIONS
20556	CONCLUSIONS
20557	BACKGROUND
20558	OBJECTIVE
20559	METHODS
20560	METHODS
20561	RESULTS
20562	RESULTS
20563	CONCLUSIONS
20564	OBJECTIVE
20565	METHODS
20566	METHODS
20567	METHODS
20568	METHODS
20569	METHODS
20570	METHODS
20571	RESULTS
20572	RESULTS
20573	RESULTS
20574	RESULTS
20575	RESULTS
20576	RESULTS
20577	RESULTS
20578	CONCLUSIONS
20579	BACKGROUND
20580	OBJECTIVE
20581	METHODS
20582	METHODS
20583	METHODS
20584	RESULTS
20585	RESULTS
20586	RESULTS
20587	CONCLUSIONS
20588	CONCLUSIONS
20589	OBJECTIVE
20590	METHODS
20591	METHODS
20592	METHODS
20593	METHODS
20594	METHODS
20595	RESULTS
20596	RESULTS
20597	RESULTS
20598	RESULTS
20599	RESULTS
20600	RESULTS
20601	RESULTS
20602	BACKGROUND
20603	CONCLUSIONS
20604	OBJECTIVE
20605	METHODS
20606	METHODS
20607	METHODS
20608	METHODS
20609	METHODS
20610	METHODS
20611	METHODS
20612	METHODS
20613	METHODS
20614	RESULTS
20615	RESULTS
20616	RESULTS
20617	RESULTS
20618	RESULTS
20619	RESULTS
20620	RESULTS
20621	CONCLUSIONS
20622	BACKGROUND
20623	BACKGROUND
20624	OBJECTIVE
20625	METHODS
20626	RESULTS
20627	RESULTS
20628	RESULTS
20629	CONCLUSIONS
20630	OBJECTIVE
20631	METHODS
20632	METHODS
20633	RESULTS
20634	RESULTS
20635	RESULTS
20636	RESULTS
20637	RESULTS
20638	CONCLUSIONS
20639	CONCLUSIONS
20640	BACKGROUND
20641	OBJECTIVE
20642	METHODS
20643	METHODS
20644	METHODS
20645	METHODS
20646	METHODS
20647	RESULTS
20648	RESULTS
20649	RESULTS
20650	RESULTS
20651	RESULTS
20652	RESULTS
20653	CONCLUSIONS
20654	CONCLUSIONS
20655	BACKGROUND
20656	BACKGROUND
20657	METHODS
20658	METHODS
20659	BACKGROUND
20660	METHODS
20661	METHODS
20662	METHODS
20663	METHODS
20664	RESULTS
20665	RESULTS
20666	RESULTS
20667	RESULTS
20668	CONCLUSIONS
20669	BACKGROUND
20670	METHODS
20671	METHODS
20672	METHODS
20673	METHODS
20674	RESULTS
20675	RESULTS
20676	RESULTS
20677	RESULTS
20678	RESULTS
20679	RESULTS
20680	BACKGROUND
20681	CONCLUSIONS
20682	OBJECTIVE
20683	METHODS
20684	METHODS
20685	RESULTS
20686	RESULTS
20687	RESULTS
20688	RESULTS
20689	RESULTS
20690	RESULTS
20691	CONCLUSIONS
20692	CONCLUSIONS
20693	RESULTS
20694	BACKGROUND
20695	METHODS
20696	METHODS
20697	METHODS
20698	METHODS
20699	METHODS
20700	METHODS
20701	METHODS
20702	METHODS
20703	RESULTS
20704	RESULTS
20705	RESULTS
20706	CONCLUSIONS
20707	BACKGROUND
20708	BACKGROUND
20709	OBJECTIVE
20710	METHODS
20711	METHODS
20712	METHODS
20713	METHODS
20714	RESULTS
20715	RESULTS
20716	CONCLUSIONS
20717	CONCLUSIONS
20718	OBJECTIVE
20719	METHODS
20720	METHODS
20721	METHODS
20722	METHODS
20723	RESULTS
20724	RESULTS
20725	RESULTS
20726	CONCLUSIONS
20727	BACKGROUND
20728	CONCLUSIONS
20729	BACKGROUND
20730	BACKGROUND
20731	RESULTS
20732	METHODS
20733	METHODS
20734	RESULTS
20735	RESULTS
20736	RESULTS
20737	CONCLUSIONS
20738	BACKGROUND
20739	BACKGROUND
20740	OBJECTIVE
20741	METHODS
20742	RESULTS
20743	METHODS
20744	METHODS
20745	RESULTS
20746	RESULTS
20747	RESULTS
20748	RESULTS
20749	CONCLUSIONS
20750	CONCLUSIONS
20751	OBJECTIVE
20752	METHODS
20753	METHODS
20754	RESULTS
20755	RESULTS
20756	RESULTS
20757	RESULTS
20758	RESULTS
20759	RESULTS
20760	CONCLUSIONS
20761	CONCLUSIONS
20762	RESULTS
20763	BACKGROUND
20764	BACKGROUND
20765	OBJECTIVE
20766	METHODS
20767	METHODS
20768	METHODS
20769	METHODS
20770	RESULTS
20771	RESULTS
20772	RESULTS
20773	CONCLUSIONS
20774	BACKGROUND
20775	OBJECTIVE
20776	METHODS
20777	METHODS
20778	RESULTS
20779	RESULTS
20780	RESULTS
20781	CONCLUSIONS
20782	BACKGROUND
20783	CONCLUSIONS
20784	OBJECTIVE
20785	METHODS
20786	METHODS
20787	METHODS
20788	RESULTS
20789	RESULTS
20790	RESULTS
20791	RESULTS
20792	RESULTS
20793	CONCLUSIONS
20794	OBJECTIVE
20795	METHODS
20796	METHODS
20797	METHODS
20798	RESULTS
20799	RESULTS
20800	RESULTS
20801	RESULTS
20802	RESULTS
20803	RESULTS
20804	CONCLUSIONS
20805	CONCLUSIONS
20806	BACKGROUND
20807	METHODS
20808	METHODS
20809	METHODS
20810	RESULTS
20811	RESULTS
20812	RESULTS
20813	CONCLUSIONS
20814	CONCLUSIONS
20815	OBJECTIVE
20816	METHODS
20817	METHODS
20818	METHODS
20819	METHODS
20820	METHODS
20821	METHODS
20822	METHODS
20823	RESULTS
20824	RESULTS
20825	RESULTS
20826	RESULTS
20827	CONCLUSIONS
20828	OBJECTIVE
20829	METHODS
20830	METHODS
20831	METHODS
20832	METHODS
20833	METHODS
20834	RESULTS
20835	RESULTS
20836	CONCLUSIONS
20837	RESULTS
20838	CONCLUSIONS
20839	OBJECTIVE
20840	METHODS
20841	METHODS
20842	METHODS
20843	RESULTS
20844	RESULTS
20845	RESULTS
20846	RESULTS
20847	RESULTS
20848	CONCLUSIONS
20849	METHODS
20850	OBJECTIVE
20851	METHODS
20852	METHODS
20853	METHODS
20854	METHODS
20855	METHODS
20856	RESULTS
20857	RESULTS
20858	RESULTS
20859	RESULTS
20860	RESULTS
20861	RESULTS
20862	CONCLUSIONS
20863	BACKGROUND
20864	BACKGROUND
20865	OBJECTIVE
20866	METHODS
20867	METHODS
20868	METHODS
20869	RESULTS
20870	RESULTS
20871	RESULTS
20872	CONCLUSIONS
20873	CONCLUSIONS
20874	BACKGROUND
20875	BACKGROUND
20876	OBJECTIVE
20877	METHODS
20878	METHODS
20879	METHODS
20880	METHODS
20881	METHODS
20882	RESULTS
20883	RESULTS
20884	RESULTS
20885	RESULTS
20886	BACKGROUND
20887	CONCLUSIONS
20888	OBJECTIVE
20889	METHODS
20890	METHODS
20891	METHODS
20892	RESULTS
20893	RESULTS
20894	CONCLUSIONS
20895	CONCLUSIONS
20896	OBJECTIVE
20897	METHODS
20898	METHODS
20899	RESULTS
20900	RESULTS
20901	METHODS
20902	RESULTS
20903	RESULTS
20904	RESULTS
20905	RESULTS
20906	CONCLUSIONS
20907	CONCLUSIONS
20908	BACKGROUND
20909	BACKGROUND
20910	BACKGROUND
20911	BACKGROUND
20912	METHODS
20913	METHODS
20914	METHODS
20915	METHODS
20916	METHODS
20917	METHODS
20918	METHODS
20919	METHODS
20920	RESULTS
20921	RESULTS
20922	CONCLUSIONS
20923	CONCLUSIONS
20924	BACKGROUND
20925	BACKGROUND
20926	METHODS
20927	METHODS
20928	METHODS
20929	RESULTS
20930	RESULTS
20931	RESULTS
20932	RESULTS
20933	RESULTS
20934	RESULTS
20935	RESULTS
20936	CONCLUSIONS
20937	CONCLUSIONS
20938	BACKGROUND
20939	METHODS
20940	METHODS
20941	METHODS
20942	METHODS
20943	METHODS
20944	METHODS
20945	METHODS
20946	RESULTS
20947	RESULTS
20948	RESULTS
20949	RESULTS
20950	CONCLUSIONS
20951	CONCLUSIONS
20952	BACKGROUND
20953	METHODS
20954	METHODS
20955	METHODS
20956	METHODS
20957	RESULTS
20958	RESULTS
20959	RESULTS
20960	RESULTS
20961	RESULTS
20962	CONCLUSIONS
20963	BACKGROUND
20964	BACKGROUND
20965	METHODS
20966	METHODS
20967	METHODS
20968	METHODS
20969	RESULTS
20970	RESULTS
20971	CONCLUSIONS
20972	BACKGROUND
20973	BACKGROUND
20974	OBJECTIVE
20975	METHODS
20976	METHODS
20977	METHODS
20978	METHODS
20979	METHODS
20980	RESULTS
20981	RESULTS
20982	CONCLUSIONS
20983	CONCLUSIONS
20984	BACKGROUND
20985	OBJECTIVE
20986	METHODS
20987	METHODS
20988	RESULTS
20989	RESULTS
20990	RESULTS
20991	RESULTS
20992	RESULTS
20993	CONCLUSIONS
20994	BACKGROUND
20995	BACKGROUND
20996	BACKGROUND
20997	METHODS
20998	METHODS
20999	RESULTS
21000	RESULTS
21001	RESULTS
21002	RESULTS
21003	RESULTS
21004	BACKGROUND
21005	BACKGROUND
21006	CONCLUSIONS
21007	BACKGROUND
21008	OBJECTIVE
21009	METHODS
21010	RESULTS
21011	RESULTS
21012	RESULTS
21013	RESULTS
21014	CONCLUSIONS
21015	CONCLUSIONS
21016	BACKGROUND
21017	BACKGROUND
21018	METHODS
21019	OBJECTIVE
21020	METHODS
21021	METHODS
21022	METHODS
21023	METHODS
21024	METHODS
21025	RESULTS
21026	RESULTS
21027	CONCLUSIONS
21028	OBJECTIVE
21029	METHODS
21030	METHODS
21031	METHODS
21032	METHODS
21033	METHODS
21034	METHODS
21035	METHODS
21036	METHODS
21037	METHODS
21038	RESULTS
21039	RESULTS
21040	RESULTS
21041	RESULTS
21042	RESULTS
21043	RESULTS
21044	RESULTS
21045	CONCLUSIONS
21046	CONCLUSIONS
21047	BACKGROUND
21048	CONCLUSIONS
21049	BACKGROUND
21050	BACKGROUND
21051	BACKGROUND
21052	METHODS
21053	METHODS
21054	RESULTS
21055	RESULTS
21056	RESULTS
21057	CONCLUSIONS
21058	OBJECTIVE
21059	METHODS
21060	METHODS
21061	METHODS
21062	RESULTS
21063	RESULTS
21064	RESULTS
21065	RESULTS
21066	RESULTS
21067	RESULTS
21068	RESULTS
21069	CONCLUSIONS
21070	CONCLUSIONS
21071	OBJECTIVE
21072	METHODS
21073	METHODS
21074	RESULTS
21075	METHODS
21076	CONCLUSIONS
21077	BACKGROUND
21078	OBJECTIVE
21079	METHODS
21080	METHODS
21081	RESULTS
21082	CONCLUSIONS
21083	CONCLUSIONS
21084	BACKGROUND
21085	RESULTS
21086	METHODS
21087	METHODS
21088	RESULTS
21089	RESULTS
21090	RESULTS
21091	RESULTS
21092	RESULTS
21093	CONCLUSIONS
21094	OBJECTIVE
21095	METHODS
21096	METHODS
21097	METHODS
21098	METHODS
21099	METHODS
21100	METHODS
21101	METHODS
21102	METHODS
21103	RESULTS
21104	RESULTS
21105	RESULTS
21106	CONCLUSIONS
21107	OBJECTIVE
21108	METHODS
21109	METHODS
21110	METHODS
21111	RESULTS
21112	RESULTS
21113	RESULTS
21114	CONCLUSIONS
21115	CONCLUSIONS
21116	CONCLUSIONS
21117	METHODS
21118	METHODS
21119	METHODS
21120	METHODS
21121	METHODS
21122	METHODS
21123	RESULTS
21124	RESULTS
21125	RESULTS
21126	RESULTS
21127	CONCLUSIONS
21128	BACKGROUND
21129	BACKGROUND
21130	BACKGROUND
21131	OBJECTIVE
21132	METHODS
21133	METHODS
21134	RESULTS
21135	RESULTS
21136	RESULTS
21137	CONCLUSIONS
21138	BACKGROUND
21139	OBJECTIVE
21140	METHODS
21141	METHODS
21142	RESULTS
21143	METHODS
21144	RESULTS
21145	METHODS
21146	RESULTS
21147	RESULTS
21148	RESULTS
21149	CONCLUSIONS
21150	BACKGROUND
21151	BACKGROUND
21152	BACKGROUND
21153	BACKGROUND
21154	BACKGROUND
21155	METHODS
21156	METHODS
21157	METHODS
21158	RESULTS
21159	RESULTS
21160	RESULTS
21161	CONCLUSIONS
21162	CONCLUSIONS
21163	OBJECTIVE
21164	METHODS
21165	METHODS
21166	METHODS
21167	RESULTS
21168	RESULTS
21169	RESULTS
21170	RESULTS
21171	CONCLUSIONS
21172	OBJECTIVE
21173	METHODS
21174	METHODS
21175	METHODS
21176	METHODS
21177	RESULTS
21178	RESULTS
21179	RESULTS
21180	RESULTS
21181	RESULTS
21182	CONCLUSIONS
21183	CONCLUSIONS
21184	OBJECTIVE
21185	METHODS
21186	METHODS
21187	METHODS
21188	METHODS
21189	METHODS
21190	METHODS
21191	RESULTS
21192	RESULTS
21193	RESULTS
21194	RESULTS
21195	RESULTS
21196	RESULTS
21197	RESULTS
21198	CONCLUSIONS
21199	CONCLUSIONS
21200	CONCLUSIONS
21201	OBJECTIVE
21202	METHODS
21203	METHODS
21204	RESULTS
21205	RESULTS
21206	RESULTS
21207	RESULTS
21208	CONCLUSIONS
21209	CONCLUSIONS
21210	BACKGROUND
21211	METHODS
21212	METHODS
21213	METHODS
21214	METHODS
21215	METHODS
21216	RESULTS
21217	RESULTS
21218	RESULTS
21219	RESULTS
21220	RESULTS
21221	RESULTS
21222	CONCLUSIONS
21223	BACKGROUND
21224	OBJECTIVE
21225	METHODS
21226	METHODS
21227	METHODS
21228	METHODS
21229	RESULTS
21230	RESULTS
21231	CONCLUSIONS
21232	CONCLUSIONS
21233	BACKGROUND
21234	BACKGROUND
21235	OBJECTIVE
21236	METHODS
21237	METHODS
21238	METHODS
21239	METHODS
21240	METHODS
21241	RESULTS
21242	RESULTS
21243	RESULTS
21244	RESULTS
21245	RESULTS
21246	CONCLUSIONS
21247	OBJECTIVE
21248	METHODS
21249	METHODS
21250	METHODS
21251	RESULTS
21252	RESULTS
21253	RESULTS
21254	RESULTS
21255	RESULTS
21256	CONCLUSIONS
21257	CONCLUSIONS
21258	BACKGROUND
21259	BACKGROUND
21260	BACKGROUND
21261	OBJECTIVE
21262	RESULTS
21263	METHODS
21264	RESULTS
21265	RESULTS
21266	RESULTS
21267	CONCLUSIONS
21268	RESULTS
21269	BACKGROUND
21270	METHODS
21271	METHODS
21272	METHODS
21273	RESULTS
21274	RESULTS
21275	RESULTS
21276	RESULTS
21277	RESULTS
21278	CONCLUSIONS
21279	CONCLUSIONS
21280	OBJECTIVE
21281	METHODS
21282	METHODS
21283	METHODS
21284	METHODS
21285	RESULTS
21286	RESULTS
21287	RESULTS
21288	RESULTS
21289	CONCLUSIONS
21290	CONCLUSIONS
21291	BACKGROUND
21292	BACKGROUND
21293	BACKGROUND
21294	BACKGROUND
21295	BACKGROUND
21296	CONCLUSIONS
21297	METHODS
21298	METHODS
21299	CONCLUSIONS
21300	CONCLUSIONS
21301	BACKGROUND
21302	OBJECTIVE
21303	METHODS
21304	METHODS
21305	METHODS
21306	METHODS
21307	METHODS
21308	METHODS
21309	RESULTS
21310	RESULTS
21311	CONCLUSIONS
21312	OBJECTIVE
21313	METHODS
21314	METHODS
21315	RESULTS
21316	RESULTS
21317	CONCLUSIONS
21318	BACKGROUND
21319	OBJECTIVE
21320	METHODS
21321	METHODS
21322	METHODS
21323	METHODS
21324	METHODS
21325	METHODS
21326	RESULTS
21327	RESULTS
21328	RESULTS
21329	CONCLUSIONS
21330	CONCLUSIONS
21331	BACKGROUND
21332	OBJECTIVE
21333	METHODS
21334	METHODS
21335	METHODS
21336	RESULTS
21337	RESULTS
21338	CONCLUSIONS
21339	RESULTS
21340	RESULTS
21341	CONCLUSIONS
21342	BACKGROUND
21343	BACKGROUND
21344	BACKGROUND
21345	METHODS
21346	METHODS
21347	METHODS
21348	METHODS
21349	METHODS
21350	METHODS
21351	RESULTS
21352	RESULTS
21353	RESULTS
21354	RESULTS
21355	RESULTS
21356	CONCLUSIONS
21357	CONCLUSIONS
21358	BACKGROUND
21359	OBJECTIVE
21360	METHODS
21361	METHODS
21362	METHODS
21363	RESULTS
21364	RESULTS
21365	RESULTS
21366	RESULTS
21367	CONCLUSIONS
21368	OBJECTIVE
21369	METHODS
21370	METHODS
21371	METHODS
21372	METHODS
21373	METHODS
21374	METHODS
21375	METHODS
21376	METHODS
21377	METHODS
21378	RESULTS
21379	RESULTS
21380	RESULTS
21381	RESULTS
21382	RESULTS
21383	RESULTS
21384	CONCLUSIONS
21385	RESULTS
21386	BACKGROUND
21387	OBJECTIVE
21388	METHODS
21389	METHODS
21390	METHODS
21391	RESULTS
21392	BACKGROUND
21393	RESULTS
21394	CONCLUSIONS
21395	CONCLUSIONS
21396	CONCLUSIONS
21397	OBJECTIVE
21398	BACKGROUND
21399	METHODS
21400	RESULTS
21401	RESULTS
21402	RESULTS
21403	RESULTS
21404	RESULTS
21405	RESULTS
21406	RESULTS
21407	RESULTS
21408	RESULTS
21409	RESULTS
21410	CONCLUSIONS
21411	RESULTS
21412	CONCLUSIONS
21413	BACKGROUND
21414	BACKGROUND
21415	METHODS
21416	METHODS
21417	METHODS
21418	METHODS
21419	METHODS
21420	RESULTS
21421	RESULTS
21422	RESULTS
21423	RESULTS
21424	RESULTS
21425	CONCLUSIONS
21426	CONCLUSIONS
21427	OBJECTIVE
21428	METHODS
21429	METHODS
21430	METHODS
21431	METHODS
21432	RESULTS
21433	RESULTS
21434	CONCLUSIONS
21435	CONCLUSIONS
21436	BACKGROUND
21437	BACKGROUND
21438	METHODS
21439	METHODS
21440	METHODS
21441	RESULTS
21442	RESULTS
21443	RESULTS
21444	RESULTS
21445	RESULTS
21446	CONCLUSIONS
21447	CONCLUSIONS
21448	OBJECTIVE
21449	METHODS
21450	METHODS
21451	METHODS
21452	METHODS
21453	RESULTS
21454	RESULTS
21455	RESULTS
21456	RESULTS
21457	RESULTS
21458	CONCLUSIONS
21459	BACKGROUND
21460	OBJECTIVE
21461	METHODS
21462	METHODS
21463	RESULTS
21464	RESULTS
21465	RESULTS
21466	RESULTS
21467	CONCLUSIONS
21468	BACKGROUND
21469	BACKGROUND
21470	OBJECTIVE
21471	METHODS
21472	RESULTS
21473	RESULTS
21474	RESULTS
21475	RESULTS
21476	RESULTS
21477	RESULTS
21478	CONCLUSIONS
21479	CONCLUSIONS
21480	BACKGROUND
21481	BACKGROUND
21482	BACKGROUND
21483	OBJECTIVE
21484	METHODS
21485	METHODS
21486	RESULTS
21487	RESULTS
21488	CONCLUSIONS
21489	CONCLUSIONS
21490	CONCLUSIONS
21491	BACKGROUND
21492	CONCLUSIONS
21493	BACKGROUND
21494	RESULTS
21495	METHODS
21496	METHODS
21497	RESULTS
21498	RESULTS
21499	RESULTS
21500	RESULTS
21501	CONCLUSIONS
21502	CONCLUSIONS
21503	CONCLUSIONS
21504	OBJECTIVE
21505	METHODS
21506	METHODS
21507	METHODS
21508	RESULTS
21509	RESULTS
21510	RESULTS
21511	RESULTS
21512	RESULTS
21513	CONCLUSIONS
21514	CONCLUSIONS
21515	BACKGROUND
21516	BACKGROUND
21517	METHODS
21518	RESULTS
21519	RESULTS
21520	RESULTS
21521	RESULTS
21522	CONCLUSIONS
21523	CONCLUSIONS
21524	BACKGROUND
21525	METHODS
21526	METHODS
21527	RESULTS
21528	RESULTS
21529	RESULTS
21530	CONCLUSIONS
21531	OBJECTIVE
21532	METHODS
21533	METHODS
21534	METHODS
21535	METHODS
21536	METHODS
21537	METHODS
21538	RESULTS
21539	RESULTS
21540	RESULTS
21541	CONCLUSIONS
21542	CONCLUSIONS
21543	BACKGROUND
21544	BACKGROUND
21545	METHODS
21546	METHODS
21547	RESULTS
21548	RESULTS
21549	RESULTS
21550	RESULTS
21551	RESULTS
21552	RESULTS
21553	RESULTS
21554	CONCLUSIONS
21555	CONCLUSIONS
21556	BACKGROUND
21557	BACKGROUND
21558	METHODS
21559	METHODS
21560	METHODS
21561	METHODS
21562	RESULTS
21563	RESULTS
21564	RESULTS
21565	RESULTS
21566	CONCLUSIONS
21567	BACKGROUND
21568	OBJECTIVE
21569	METHODS
21570	METHODS
21571	RESULTS
21572	RESULTS
21573	RESULTS
21574	RESULTS
21575	RESULTS
21576	RESULTS
21577	RESULTS
21578	RESULTS
21579	CONCLUSIONS
21580	CONCLUSIONS
21581	BACKGROUND
21582	BACKGROUND
21583	BACKGROUND
21584	OBJECTIVE
21585	METHODS
21586	BACKGROUND
21587	METHODS
21588	METHODS
21589	RESULTS
21590	RESULTS
21591	CONCLUSIONS
21592	CONCLUSIONS
21593	OBJECTIVE
21594	METHODS
21595	RESULTS
21596	RESULTS
21597	RESULTS
21598	RESULTS
21599	CONCLUSIONS
21600	BACKGROUND
21601	BACKGROUND
21602	OBJECTIVE
21603	METHODS
21604	METHODS
21605	CONCLUSIONS
21606	RESULTS
21607	RESULTS
21608	RESULTS
21609	RESULTS
21610	RESULTS
21611	CONCLUSIONS
21612	BACKGROUND
21613	OBJECTIVE
21614	METHODS
21615	METHODS
21616	METHODS
21617	RESULTS
21618	RESULTS
21619	CONCLUSIONS
21620	CONCLUSIONS
21621	CONCLUSIONS
21622	OBJECTIVE
21623	BACKGROUND
21624	BACKGROUND
21625	OBJECTIVE
21626	METHODS
21627	METHODS
21628	METHODS
21629	METHODS
21630	METHODS
21631	METHODS
21632	RESULTS
21633	RESULTS
21634	RESULTS
21635	RESULTS
21636	RESULTS
21637	RESULTS
21638	RESULTS
21639	CONCLUSIONS
21640	RESULTS
21641	OBJECTIVE
21642	METHODS
21643	METHODS
21644	METHODS
21645	METHODS
21646	RESULTS
21647	METHODS
21648	RESULTS
21649	RESULTS
21650	RESULTS
21651	RESULTS
21652	RESULTS
21653	CONCLUSIONS
21654	BACKGROUND
21655	METHODS
21656	METHODS
21657	METHODS
21658	METHODS
21659	RESULTS
21660	RESULTS
21661	RESULTS
21662	CONCLUSIONS
21663	RESULTS
21664	CONCLUSIONS
21665	OBJECTIVE
21666	METHODS
21667	METHODS
21668	METHODS
21669	METHODS
21670	RESULTS
21671	RESULTS
21672	RESULTS
21673	METHODS
21674	RESULTS
21675	BACKGROUND
21676	OBJECTIVE
21677	METHODS
21678	RESULTS
21679	RESULTS
21680	CONCLUSIONS
21681	OBJECTIVE
21682	METHODS
21683	METHODS
21684	METHODS
21685	METHODS
21686	METHODS
21687	RESULTS
21688	RESULTS
21689	RESULTS
21690	CONCLUSIONS
21691	OBJECTIVE
21692	METHODS
21693	METHODS
21694	METHODS
21695	RESULTS
21696	RESULTS
21697	RESULTS
21698	RESULTS
21699	RESULTS
21700	RESULTS
21701	RESULTS
21702	RESULTS
21703	RESULTS
21704	CONCLUSIONS
21705	CONCLUSIONS
21706	OBJECTIVE
21707	METHODS
21708	METHODS
21709	METHODS
21710	METHODS
21711	METHODS
21712	METHODS
21713	METHODS
21714	METHODS
21715	RESULTS
21716	RESULTS
21717	RESULTS
21718	RESULTS
21719	CONCLUSIONS
21720	CONCLUSIONS
21721	CONCLUSIONS
21722	BACKGROUND
21723	BACKGROUND
21724	METHODS
21725	METHODS
21726	RESULTS
21727	RESULTS
21728	RESULTS
21729	RESULTS
21730	RESULTS
21731	RESULTS
21732	CONCLUSIONS
21733	BACKGROUND
21734	BACKGROUND
21735	BACKGROUND
21736	METHODS
21737	METHODS
21738	METHODS
21739	METHODS
21740	METHODS
21741	METHODS
21742	RESULTS
21743	RESULTS
21744	RESULTS
21745	RESULTS
21746	RESULTS
21747	RESULTS
21748	CONCLUSIONS
21749	BACKGROUND
21750	BACKGROUND
21751	OBJECTIVE
21752	METHODS
21753	METHODS
21754	METHODS
21755	RESULTS
21756	RESULTS
21757	RESULTS
21758	CONCLUSIONS
21759	RESULTS
21760	BACKGROUND
21761	BACKGROUND
21762	BACKGROUND
21763	BACKGROUND
21764	BACKGROUND
21765	METHODS
21766	METHODS
21767	METHODS
21768	METHODS
21769	METHODS
21770	METHODS
21771	METHODS
21772	RESULTS
21773	RESULTS
21774	RESULTS
21775	RESULTS
21776	RESULTS
21777	RESULTS
21778	CONCLUSIONS
21779	CONCLUSIONS
21780	BACKGROUND
21781	OBJECTIVE
21782	METHODS
21783	METHODS
21784	RESULTS
21785	RESULTS
21786	RESULTS
21787	CONCLUSIONS
21788	RESULTS
21789	CONCLUSIONS
21790	CONCLUSIONS
21791	CONCLUSIONS
21792	BACKGROUND
21793	BACKGROUND
21794	METHODS
21795	METHODS
21796	RESULTS
21797	RESULTS
21798	RESULTS
21799	RESULTS
21800	CONCLUSIONS
21801	CONCLUSIONS
21802	BACKGROUND
21803	BACKGROUND
21804	METHODS
21805	METHODS
21806	METHODS
21807	RESULTS
21808	RESULTS
21809	RESULTS
21810	RESULTS
21811	RESULTS
21812	RESULTS
21813	BACKGROUND
21814	CONCLUSIONS
21815	BACKGROUND
21816	CONCLUSIONS
21817	OBJECTIVE
21818	METHODS
21819	METHODS
21820	METHODS
21821	RESULTS
21822	RESULTS
21823	RESULTS
21824	RESULTS
21825	CONCLUSIONS
21826	CONCLUSIONS
21827	CONCLUSIONS
21828	BACKGROUND
21829	BACKGROUND
21830	OBJECTIVE
21831	METHODS
21832	METHODS
21833	METHODS
21834	METHODS
21835	RESULTS
21836	RESULTS
21837	RESULTS
21838	RESULTS
21839	RESULTS
21840	CONCLUSIONS
21841	RESULTS
21842	RESULTS
21843	BACKGROUND
21844	METHODS
21845	METHODS
21846	RESULTS
21847	RESULTS
21848	RESULTS
21849	RESULTS
21850	CONCLUSIONS
21851	BACKGROUND
21852	OBJECTIVE
21853	METHODS
21854	METHODS
21855	RESULTS
21856	RESULTS
21857	RESULTS
21858	RESULTS
21859	CONCLUSIONS
21860	CONCLUSIONS
21861	RESULTS
21862	CONCLUSIONS
21863	BACKGROUND
21864	BACKGROUND
21865	METHODS
21866	METHODS
21867	METHODS
21868	RESULTS
21869	RESULTS
21870	RESULTS
21871	RESULTS
21872	CONCLUSIONS
21873	CONCLUSIONS
21874	CONCLUSIONS
21875	BACKGROUND
21876	BACKGROUND
21877	BACKGROUND
21878	METHODS
21879	METHODS
21880	METHODS
21881	METHODS
21882	RESULTS
21883	RESULTS
21884	CONCLUSIONS
21885	CONCLUSIONS
21886	OBJECTIVE
21887	METHODS
21888	METHODS
21889	METHODS
21890	RESULTS
21891	RESULTS
21892	RESULTS
21893	CONCLUSIONS
21894	OBJECTIVE
21895	METHODS
21896	METHODS
21897	METHODS
21898	METHODS
21899	METHODS
21900	METHODS
21901	RESULTS
21902	RESULTS
21903	RESULTS
21904	RESULTS
21905	RESULTS
21906	RESULTS
21907	BACKGROUND
21908	OBJECTIVE
21909	METHODS
21910	METHODS
21911	METHODS
21912	METHODS
21913	RESULTS
21914	RESULTS
21915	RESULTS
21916	RESULTS
21917	RESULTS
21918	CONCLUSIONS
21919	RESULTS
21920	RESULTS
21921	RESULTS
21922	CONCLUSIONS
21923	CONCLUSIONS
21924	RESULTS
21925	BACKGROUND
21926	BACKGROUND
21927	METHODS
21928	METHODS
21929	METHODS
21930	METHODS
21931	METHODS
21932	METHODS
21933	METHODS
21934	RESULTS
21935	RESULTS
21936	RESULTS
21937	RESULTS
21938	CONCLUSIONS
21939	OBJECTIVE
21940	METHODS
21941	METHODS
21942	METHODS
21943	METHODS
21944	RESULTS
21945	RESULTS
21946	RESULTS
21947	CONCLUSIONS
21948	OBJECTIVE
21949	OBJECTIVE
21950	METHODS
21951	METHODS
21952	METHODS
21953	METHODS
21954	RESULTS
21955	RESULTS
21956	RESULTS
21957	RESULTS
21958	CONCLUSIONS
21959	CONCLUSIONS
21960	CONCLUSIONS
21961	OBJECTIVE
21962	METHODS
21963	METHODS
21964	METHODS
21965	METHODS
21966	RESULTS
21967	RESULTS
21968	RESULTS
21969	CONCLUSIONS
21970	CONCLUSIONS
21971	BACKGROUND
21972	BACKGROUND
21973	METHODS
21974	METHODS
21975	RESULTS
21976	RESULTS
21977	RESULTS
21978	RESULTS
21979	CONCLUSIONS
21980	BACKGROUND
21981	OBJECTIVE
21982	METHODS
21983	METHODS
21984	METHODS
21985	METHODS
21986	METHODS
21987	METHODS
21988	METHODS
21989	RESULTS
21990	RESULTS
21991	RESULTS
21992	RESULTS
21993	CONCLUSIONS
21994	CONCLUSIONS
21995	OBJECTIVE
21996	METHODS
21997	METHODS
21998	RESULTS
21999	RESULTS
22000	RESULTS
22001	RESULTS
22002	RESULTS
22003	CONCLUSIONS
22004	CONCLUSIONS
22005	BACKGROUND
22006	OBJECTIVE
22007	METHODS
22008	METHODS
22009	RESULTS
22010	RESULTS
22011	RESULTS
22012	RESULTS
22013	RESULTS
22014	CONCLUSIONS
22015	CONCLUSIONS
22016	CONCLUSIONS
22017	BACKGROUND
22018	BACKGROUND
22019	METHODS
22020	METHODS
22021	METHODS
22022	METHODS
22023	RESULTS
22024	RESULTS
22025	RESULTS
22026	RESULTS
22027	RESULTS
22028	RESULTS
22029	RESULTS
22030	CONCLUSIONS
22031	RESULTS
22032	OBJECTIVE
22033	METHODS
22034	METHODS
22035	METHODS
22036	METHODS
22037	RESULTS
22038	RESULTS
22039	RESULTS
22040	RESULTS
22041	RESULTS
22042	RESULTS
22043	RESULTS
22044	CONCLUSIONS
22045	RESULTS
22046	RESULTS
22047	RESULTS
22048	CONCLUSIONS
22049	BACKGROUND
22050	BACKGROUND
22051	RESULTS
22052	RESULTS
22053	RESULTS
22054	RESULTS
22055	RESULTS
22056	RESULTS
22057	RESULTS
22058	CONCLUSIONS
22059	RESULTS
22060	BACKGROUND
22061	BACKGROUND
22062	OBJECTIVE
22063	METHODS
22064	METHODS
22065	RESULTS
22066	RESULTS
22067	CONCLUSIONS
22068	CONCLUSIONS
22069	BACKGROUND
22070	BACKGROUND
22071	OBJECTIVE
22072	METHODS
22073	METHODS
22074	METHODS
22075	METHODS
22076	RESULTS
22077	RESULTS
22078	RESULTS
22079	RESULTS
22080	CONCLUSIONS
22081	RESULTS
22082	BACKGROUND
22083	BACKGROUND
22084	METHODS
22085	METHODS
22086	METHODS
22087	RESULTS
22088	RESULTS
22089	RESULTS
22090	CONCLUSIONS
22091	CONCLUSIONS
22092	OBJECTIVE
22093	METHODS
22094	METHODS
22095	METHODS
22096	METHODS
22097	RESULTS
22098	RESULTS
22099	RESULTS
22100	CONCLUSIONS
22101	OBJECTIVE
22102	METHODS
22103	RESULTS
22104	METHODS
22105	METHODS
22106	RESULTS
22107	RESULTS
22108	RESULTS
22109	RESULTS
22110	RESULTS
22111	CONCLUSIONS
22112	BACKGROUND
22113	OBJECTIVE
22114	METHODS
22115	RESULTS
22116	RESULTS
22117	RESULTS
22118	CONCLUSIONS
22119	CONCLUSIONS
22120	BACKGROUND
22121	BACKGROUND
22122	BACKGROUND
22123	METHODS
22124	RESULTS
22125	RESULTS
22126	RESULTS
22127	CONCLUSIONS
22128	CONCLUSIONS
22129	BACKGROUND
22130	OBJECTIVE
22131	METHODS
22132	METHODS
22133	RESULTS
22134	RESULTS
22135	RESULTS
22136	RESULTS
22137	RESULTS
22138	CONCLUSIONS
22139	CONCLUSIONS
22140	CONCLUSIONS
22141	OBJECTIVE
22142	METHODS
22143	METHODS
22144	METHODS
22145	METHODS
22146	METHODS
22147	METHODS
22148	RESULTS
22149	RESULTS
22150	RESULTS
22151	RESULTS
22152	CONCLUSIONS
22153	CONCLUSIONS
22154	OBJECTIVE
22155	METHODS
22156	METHODS
22157	METHODS
22158	METHODS
22159	RESULTS
22160	RESULTS
22161	RESULTS
22162	RESULTS
22163	CONCLUSIONS
22164	BACKGROUND
22165	BACKGROUND
22166	OBJECTIVE
22167	METHODS
22168	METHODS
22169	METHODS
22170	METHODS
22171	METHODS
22172	RESULTS
22173	RESULTS
22174	RESULTS
22175	RESULTS
22176	RESULTS
22177	RESULTS
22178	CONCLUSIONS
22179	RESULTS
22180	RESULTS
22181	CONCLUSIONS
22182	BACKGROUND
22183	BACKGROUND
22184	BACKGROUND
22185	METHODS
22186	RESULTS
22187	RESULTS
22188	RESULTS
22189	CONCLUSIONS
22190	BACKGROUND
22191	BACKGROUND
22192	RESULTS
22193	RESULTS
22194	RESULTS
22195	RESULTS
22196	RESULTS
22197	RESULTS
22198	RESULTS
22199	CONCLUSIONS
22200	BACKGROUND
22201	BACKGROUND
22202	OBJECTIVE
22203	OBJECTIVE
22204	METHODS
22205	METHODS
22206	METHODS
22207	METHODS
22208	METHODS
22209	RESULTS
22210	RESULTS
22211	RESULTS
22212	RESULTS
22213	RESULTS
22214	CONCLUSIONS
22215	OBJECTIVE
22216	CONCLUSIONS
22217	METHODS
22218	METHODS
22219	METHODS
22220	METHODS
22221	METHODS
22222	METHODS
22223	METHODS
22224	RESULTS
22225	RESULTS
22226	CONCLUSIONS
22227	CONCLUSIONS
22228	CONCLUSIONS
22229	BACKGROUND
22230	BACKGROUND
22231	METHODS
22232	METHODS
22233	METHODS
22234	METHODS
22235	METHODS
22236	RESULTS
22237	RESULTS
22238	RESULTS
22239	CONCLUSIONS
22240	OBJECTIVE
22241	METHODS
22242	METHODS
22243	METHODS
22244	METHODS
22245	METHODS
22246	METHODS
22247	METHODS
22248	METHODS
22249	METHODS
22250	RESULTS
22251	RESULTS
22252	CONCLUSIONS
22253	CONCLUSIONS
22254	OBJECTIVE
22255	OBJECTIVE
22256	METHODS
22257	METHODS
22258	RESULTS
22259	RESULTS
22260	RESULTS
22261	CONCLUSIONS
22262	BACKGROUND
22263	BACKGROUND
22264	BACKGROUND
22265	OBJECTIVE
22266	OBJECTIVE
22267	METHODS
22268	METHODS
22269	METHODS
22270	METHODS
22271	RESULTS
22272	METHODS
22273	METHODS
22274	RESULTS
22275	RESULTS
22276	CONCLUSIONS
22277	OBJECTIVE
22278	METHODS
22279	METHODS
22280	RESULTS
22281	RESULTS
22282	RESULTS
22283	RESULTS
22284	RESULTS
22285	RESULTS
22286	RESULTS
22287	CONCLUSIONS
22288	OBJECTIVE
22289	METHODS
22290	METHODS
22291	METHODS
22292	RESULTS
22293	RESULTS
22294	RESULTS
22295	RESULTS
22296	RESULTS
22297	CONCLUSIONS
22298	RESULTS
22299	BACKGROUND
22300	CONCLUSIONS
22301	METHODS
22302	METHODS
22303	OBJECTIVE
22304	RESULTS
22305	RESULTS
22306	RESULTS
22307	RESULTS
22308	CONCLUSIONS
22309	BACKGROUND
22310	BACKGROUND
22311	OBJECTIVE
22312	METHODS
22313	METHODS
22314	METHODS
22315	METHODS
22316	METHODS
22317	METHODS
22318	RESULTS
22319	RESULTS
22320	RESULTS
22321	RESULTS
22322	RESULTS
22323	RESULTS
22324	CONCLUSIONS
22325	CONCLUSIONS
22326	CONCLUSIONS
22327	OBJECTIVE
22328	BACKGROUND
22329	METHODS
22330	METHODS
22331	METHODS
22332	RESULTS
22333	RESULTS
22334	RESULTS
22335	RESULTS
22336	CONCLUSIONS
22337	CONCLUSIONS
22338	OBJECTIVE
22339	METHODS
22340	METHODS
22341	METHODS
22342	METHODS
22343	METHODS
22344	RESULTS
22345	RESULTS
22346	RESULTS
22347	CONCLUSIONS
22348	CONCLUSIONS
22349	BACKGROUND
22350	BACKGROUND
22351	BACKGROUND
22352	METHODS
22353	METHODS
22354	RESULTS
22355	RESULTS
22356	RESULTS
22357	RESULTS
22358	RESULTS
22359	CONCLUSIONS
22360	CONCLUSIONS
22361	OBJECTIVE
22362	METHODS
22363	METHODS
22364	METHODS
22365	METHODS
22366	METHODS
22367	RESULTS
22368	RESULTS
22369	RESULTS
22370	RESULTS
22371	CONCLUSIONS
22372	CONCLUSIONS
22373	BACKGROUND
22374	BACKGROUND
22375	BACKGROUND
22376	METHODS
22377	METHODS
22378	RESULTS
22379	RESULTS
22380	RESULTS
22381	RESULTS
22382	RESULTS
22383	RESULTS
22384	RESULTS
22385	CONCLUSIONS
22386	OBJECTIVE
22387	METHODS
22388	METHODS
22389	METHODS
22390	RESULTS
22391	RESULTS
22392	RESULTS
22393	CONCLUSIONS
22394	OBJECTIVE
22395	OBJECTIVE
22396	METHODS
22397	METHODS
22398	METHODS
22399	METHODS
22400	RESULTS
22401	CONCLUSIONS
22402	OBJECTIVE
22403	METHODS
22404	METHODS
22405	METHODS
22406	METHODS
22407	METHODS
22408	RESULTS
22409	RESULTS
22410	RESULTS
22411	RESULTS
22412	RESULTS
22413	CONCLUSIONS
22414	OBJECTIVE
22415	METHODS
22416	RESULTS
22417	RESULTS
22418	RESULTS
22419	CONCLUSIONS
22420	RESULTS
22421	CONCLUSIONS
22422	CONCLUSIONS
22423	CONCLUSIONS
22424	RESULTS
22425	RESULTS
22426	BACKGROUND
22427	OBJECTIVE
22428	BACKGROUND
22429	METHODS
22430	METHODS
22431	METHODS
22432	RESULTS
22433	RESULTS
22434	RESULTS
22435	CONCLUSIONS
22436	CONCLUSIONS
22437	BACKGROUND
22438	METHODS
22439	METHODS
22440	METHODS
22441	RESULTS
22442	RESULTS
22443	CONCLUSIONS
22444	BACKGROUND
22445	BACKGROUND
22446	BACKGROUND
22447	BACKGROUND
22448	BACKGROUND
22449	BACKGROUND
22450	METHODS
22451	METHODS
22452	METHODS
22453	METHODS
22454	RESULTS
22455	RESULTS
22456	RESULTS
22457	RESULTS
22458	CONCLUSIONS
22459	CONCLUSIONS
22460	BACKGROUND
22461	BACKGROUND
22462	BACKGROUND
22463	BACKGROUND
22464	BACKGROUND
22465	METHODS
22466	METHODS
22467	METHODS
22468	METHODS
22469	METHODS
22470	CONCLUSIONS
22471	CONCLUSIONS
22472	METHODS
22473	BACKGROUND
22474	BACKGROUND
22475	METHODS
22476	RESULTS
22477	RESULTS
22478	RESULTS
22479	RESULTS
22480	CONCLUSIONS
22481	CONCLUSIONS
22482	OBJECTIVE
22483	METHODS
22484	METHODS
22485	METHODS
22486	METHODS
22487	METHODS
22488	RESULTS
22489	RESULTS
22490	RESULTS
22491	CONCLUSIONS
22492	CONCLUSIONS
22493	OBJECTIVE
22494	METHODS
22495	METHODS
22496	METHODS
22497	RESULTS
22498	RESULTS
22499	RESULTS
22500	RESULTS
22501	RESULTS
22502	RESULTS
22503	CONCLUSIONS
22504	CONCLUSIONS
22505	OBJECTIVE
22506	METHODS
22507	METHODS
22508	METHODS
22509	METHODS
22510	METHODS
22511	METHODS
22512	RESULTS
22513	RESULTS
22514	RESULTS
22515	RESULTS
22516	CONCLUSIONS
22517	OBJECTIVE
22518	METHODS
22519	METHODS
22520	METHODS
22521	METHODS
22522	METHODS
22523	METHODS
22524	RESULTS
22525	RESULTS
22526	RESULTS
22527	RESULTS
22528	RESULTS
22529	RESULTS
22530	RESULTS
22531	CONCLUSIONS
22532	BACKGROUND
22533	OBJECTIVE
22534	METHODS
22535	METHODS
22536	RESULTS
22537	RESULTS
22538	CONCLUSIONS
22539	CONCLUSIONS
22540	CONCLUSIONS
22541	OBJECTIVE
22542	METHODS
22543	METHODS
22544	METHODS
22545	METHODS
22546	RESULTS
22547	RESULTS
22548	RESULTS
22549	RESULTS
22550	CONCLUSIONS
22551	CONCLUSIONS
22552	BACKGROUND
22553	OBJECTIVE
22554	METHODS
22555	METHODS
22556	METHODS
22557	RESULTS
22558	RESULTS
22559	RESULTS
22560	RESULTS
22561	RESULTS
22562	RESULTS
22563	RESULTS
22564	RESULTS
22565	CONCLUSIONS
22566	CONCLUSIONS
22567	CONCLUSIONS
22568	BACKGROUND
22569	BACKGROUND
22570	METHODS
22571	METHODS
22572	METHODS
22573	METHODS
22574	RESULTS
22575	RESULTS
22576	RESULTS
22577	CONCLUSIONS
22578	OBJECTIVE
22579	METHODS
22580	METHODS
22581	METHODS
22582	RESULTS
22583	RESULTS
22584	CONCLUSIONS
22585	OBJECTIVE
22586	METHODS
22587	METHODS
22588	METHODS
22589	METHODS
22590	METHODS
22591	METHODS
22592	RESULTS
22593	RESULTS
22594	RESULTS
22595	RESULTS
22596	CONCLUSIONS
22597	BACKGROUND
22598	METHODS
22599	METHODS
22600	METHODS
22601	METHODS
22602	RESULTS
22603	RESULTS
22604	CONCLUSIONS
22605	RESULTS
22606	CONCLUSIONS
22607	CONCLUSIONS
22608	BACKGROUND
22609	BACKGROUND
22610	CONCLUSIONS
22611	BACKGROUND
22612	METHODS
22613	METHODS
22614	RESULTS
22615	RESULTS
22616	RESULTS
22617	RESULTS
22618	RESULTS
22619	CONCLUSIONS
22620	RESULTS
22621	RESULTS
22622	CONCLUSIONS
22623	CONCLUSIONS
22624	OBJECTIVE
22625	OBJECTIVE
22626	METHODS
22627	RESULTS
22628	RESULTS
22629	METHODS
22630	RESULTS
22631	RESULTS
22632	RESULTS
22633	RESULTS
22634	RESULTS
22635	CONCLUSIONS
22636	CONCLUSIONS
22637	CONCLUSIONS
22638	OBJECTIVE
22639	METHODS
22640	METHODS
22641	RESULTS
22642	RESULTS
22643	RESULTS
22644	RESULTS
22645	CONCLUSIONS
22646	CONCLUSIONS
22647	CONCLUSIONS
22648	OBJECTIVE
22649	METHODS
22650	METHODS
22651	METHODS
22652	RESULTS
22653	RESULTS
22654	RESULTS
22655	RESULTS
22656	RESULTS
22657	RESULTS
22658	CONCLUSIONS
22659	BACKGROUND
22660	BACKGROUND
22661	BACKGROUND
22662	OBJECTIVE
22663	METHODS
22664	METHODS
22665	METHODS
22666	METHODS
22667	METHODS
22668	RESULTS
22669	RESULTS
22670	RESULTS
22671	RESULTS
22672	RESULTS
22673	CONCLUSIONS
22674	OBJECTIVE
22675	METHODS
22676	METHODS
22677	METHODS
22678	METHODS
22679	METHODS
22680	RESULTS
22681	RESULTS
22682	RESULTS
22683	RESULTS
22684	CONCLUSIONS
22685	OBJECTIVE
22686	METHODS
22687	METHODS
22688	METHODS
22689	RESULTS
22690	METHODS
22691	METHODS
22692	METHODS
22693	METHODS
22694	RESULTS
22695	RESULTS
22696	CONCLUSIONS
22697	METHODS
22698	METHODS
22699	METHODS
22700	METHODS
22701	METHODS
22702	RESULTS
22703	RESULTS
22704	CONCLUSIONS
22705	RESULTS
22706	RESULTS
22707	RESULTS
22708	RESULTS
22709	CONCLUSIONS
22710	CONCLUSIONS
22711	BACKGROUND
22712	BACKGROUND
22713	BACKGROUND
22714	CONCLUSIONS
22715	OBJECTIVE
22716	METHODS
22717	METHODS
22718	RESULTS
22719	RESULTS
22720	RESULTS
22721	CONCLUSIONS
22722	BACKGROUND
22723	BACKGROUND
22724	OBJECTIVE
22725	METHODS
22726	METHODS
22727	METHODS
22728	METHODS
22729	METHODS
22730	METHODS
22731	RESULTS
22732	RESULTS
22733	RESULTS
22734	RESULTS
22735	CONCLUSIONS
22736	CONCLUSIONS
22737	BACKGROUND
22738	OBJECTIVE
22739	METHODS
22740	METHODS
22741	METHODS
22742	METHODS
22743	RESULTS
22744	RESULTS
22745	CONCLUSIONS
22746	BACKGROUND
22747	BACKGROUND
22748	OBJECTIVE
22749	OBJECTIVE
22750	METHODS
22751	METHODS
22752	RESULTS
22753	RESULTS
22754	CONCLUSIONS
22755	CONCLUSIONS
22756	BACKGROUND
22757	BACKGROUND
22758	OBJECTIVE
22759	METHODS
22760	METHODS
22761	METHODS
22762	METHODS
22763	METHODS
22764	RESULTS
22765	RESULTS
22766	RESULTS
22767	RESULTS
22768	CONCLUSIONS
22769	BACKGROUND
22770	OBJECTIVE
22771	METHODS
22772	METHODS
22773	METHODS
22774	METHODS
22775	METHODS
22776	RESULTS
22777	RESULTS
22778	RESULTS
22779	CONCLUSIONS
22780	OBJECTIVE
22781	METHODS
22782	METHODS
22783	METHODS
22784	METHODS
22785	METHODS
22786	RESULTS
22787	RESULTS
22788	RESULTS
22789	CONCLUSIONS
22790	CONCLUSIONS
22791	CONCLUSIONS
22792	BACKGROUND
22793	BACKGROUND
22794	METHODS
22795	METHODS
22796	RESULTS
22797	RESULTS
22798	RESULTS
22799	RESULTS
22800	RESULTS
22801	RESULTS
22802	CONCLUSIONS
22803	BACKGROUND
22804	OBJECTIVE
22805	METHODS
22806	METHODS
22807	METHODS
22808	RESULTS
22809	RESULTS
22810	CONCLUSIONS
22811	OBJECTIVE
22812	METHODS
22813	METHODS
22814	RESULTS
22815	RESULTS
22816	RESULTS
22817	RESULTS
22818	RESULTS
22819	RESULTS
22820	BACKGROUND
22821	OBJECTIVE
22822	METHODS
22823	METHODS
22824	METHODS
22825	METHODS
22826	RESULTS
22827	RESULTS
22828	RESULTS
22829	RESULTS
22830	RESULTS
22831	RESULTS
22832	RESULTS
22833	RESULTS
22834	RESULTS
22835	BACKGROUND
22836	METHODS
22837	METHODS
22838	METHODS
22839	METHODS
22840	RESULTS
22841	RESULTS
22842	RESULTS
22843	RESULTS
22844	RESULTS
22845	RESULTS
22846	RESULTS
22847	BACKGROUND
22848	BACKGROUND
22849	BACKGROUND
22850	OBJECTIVE
22851	METHODS
22852	METHODS
22853	RESULTS
22854	METHODS
22855	METHODS
22856	RESULTS
22857	RESULTS
22858	RESULTS
22859	CONCLUSIONS
22860	RESULTS
22861	BACKGROUND
22862	BACKGROUND
22863	BACKGROUND
22864	METHODS
22865	METHODS
22866	METHODS
22867	RESULTS
22868	RESULTS
22869	RESULTS
22870	RESULTS
22871	RESULTS
22872	CONCLUSIONS
22873	CONCLUSIONS
22874	CONCLUSIONS
22875	CONCLUSIONS
22876	OBJECTIVE
22877	METHODS
22878	METHODS
22879	RESULTS
22880	RESULTS
22881	RESULTS
22882	RESULTS
22883	RESULTS
22884	CONCLUSIONS
22885	CONCLUSIONS
22886	BACKGROUND
22887	BACKGROUND
22888	RESULTS
22889	METHODS
22890	RESULTS
22891	RESULTS
22892	RESULTS
22893	CONCLUSIONS
22894	CONCLUSIONS
22895	CONCLUSIONS
22896	BACKGROUND
22897	BACKGROUND
22898	OBJECTIVE
22899	METHODS
22900	METHODS
22901	RESULTS
22902	RESULTS
22903	RESULTS
22904	METHODS
22905	CONCLUSIONS
22906	OBJECTIVE
22907	METHODS
22908	METHODS
22909	RESULTS
22910	CONCLUSIONS
22911	CONCLUSIONS
22912	OBJECTIVE
22913	METHODS
22914	METHODS
22915	METHODS
22916	METHODS
22917	RESULTS
22918	RESULTS
22919	RESULTS
22920	RESULTS
22921	RESULTS
22922	RESULTS
22923	CONCLUSIONS
22924	CONCLUSIONS
22925	BACKGROUND
22926	OBJECTIVE
22927	OBJECTIVE
22928	OBJECTIVE
22929	OBJECTIVE
22930	METHODS
22931	METHODS
22932	METHODS
22933	RESULTS
22934	RESULTS
22935	RESULTS
22936	METHODS
22937	RESULTS
22938	RESULTS
22939	RESULTS
22940	RESULTS
22941	RESULTS
22942	CONCLUSIONS
22943	METHODS
22944	METHODS
22945	METHODS
22946	METHODS
22947	METHODS
22948	RESULTS
22949	RESULTS
22950	RESULTS
22951	CONCLUSIONS
22952	OBJECTIVE
22953	METHODS
22954	METHODS
22955	METHODS
22956	METHODS
22957	METHODS
22958	RESULTS
22959	RESULTS
22960	RESULTS
22961	RESULTS
22962	RESULTS
22963	CONCLUSIONS
22964	OBJECTIVE
22965	METHODS
22966	METHODS
22967	RESULTS
22968	CONCLUSIONS
22969	OBJECTIVE
22970	METHODS
22971	METHODS
22972	METHODS
22973	METHODS
22974	RESULTS
22975	RESULTS
22976	RESULTS
22977	CONCLUSIONS
22978	CONCLUSIONS
22979	BACKGROUND
22980	BACKGROUND
22981	METHODS
22982	METHODS
22983	RESULTS
22984	RESULTS
22985	RESULTS
22986	RESULTS
22987	RESULTS
22988	RESULTS
22989	RESULTS
22990	CONCLUSIONS
22991	CONCLUSIONS
22992	CONCLUSIONS
22993	BACKGROUND
22994	METHODS
22995	RESULTS
22996	METHODS
22997	METHODS
22998	RESULTS
22999	RESULTS
23000	RESULTS
23001	RESULTS
23002	RESULTS
23003	CONCLUSIONS
23004	OBJECTIVE
23005	METHODS
23006	METHODS
23007	METHODS
23008	METHODS
23009	RESULTS
23010	RESULTS
23011	RESULTS
23012	CONCLUSIONS
23013	CONCLUSIONS
23014	CONCLUSIONS
23015	OBJECTIVE
23016	METHODS
23017	METHODS
23018	METHODS
23019	RESULTS
23020	RESULTS
23021	RESULTS
23022	RESULTS
23023	RESULTS
23024	RESULTS
23025	CONCLUSIONS
23026	CONCLUSIONS
23027	CONCLUSIONS
23028	BACKGROUND
23029	BACKGROUND
23030	BACKGROUND
23031	METHODS
23032	METHODS
23033	METHODS
23034	RESULTS
23035	RESULTS
23036	RESULTS
23037	CONCLUSIONS
23038	RESULTS
23039	OBJECTIVE
23040	METHODS
23041	METHODS
23042	METHODS
23043	METHODS
23044	METHODS
23045	RESULTS
23046	RESULTS
23047	RESULTS
23048	RESULTS
23049	RESULTS
23050	RESULTS
23051	RESULTS
23052	RESULTS
23053	CONCLUSIONS
23054	CONCLUSIONS
23055	CONCLUSIONS
23056	CONCLUSIONS
23057	OBJECTIVE
23058	METHODS
23059	METHODS
23060	METHODS
23061	METHODS
23062	RESULTS
23063	RESULTS
23064	RESULTS
23065	RESULTS
23066	CONCLUSIONS
23067	OBJECTIVE
23068	METHODS
23069	METHODS
23070	METHODS
23071	RESULTS
23072	RESULTS
23073	CONCLUSIONS
23074	BACKGROUND
23075	BACKGROUND
23076	OBJECTIVE
23077	METHODS
23078	METHODS
23079	RESULTS
23080	RESULTS
23081	RESULTS
23082	CONCLUSIONS
23083	OBJECTIVE
23084	METHODS
23085	METHODS
23086	METHODS
23087	METHODS
23088	METHODS
23089	METHODS
23090	RESULTS
23091	METHODS
23092	METHODS
23093	METHODS
23094	RESULTS
23095	RESULTS
23096	RESULTS
23097	RESULTS
23098	RESULTS
23099	RESULTS
23100	RESULTS
23101	BACKGROUND
23102	CONCLUSIONS
23103	CONCLUSIONS
23104	OBJECTIVE
23105	METHODS
23106	METHODS
23107	METHODS
23108	METHODS
23109	METHODS
23110	METHODS
23111	RESULTS
23112	RESULTS
23113	RESULTS
23114	RESULTS
23115	RESULTS
23116	RESULTS
23117	RESULTS
23118	RESULTS
23119	RESULTS
23120	RESULTS
23121	RESULTS
23122	RESULTS
23123	CONCLUSIONS
23124	CONCLUSIONS
23125	CONCLUSIONS
23126	CONCLUSIONS
23127	CONCLUSIONS
23128	CONCLUSIONS
23129	CONCLUSIONS
23130	BACKGROUND
23131	BACKGROUND
23132	METHODS
23133	METHODS
23134	METHODS
23135	METHODS
23136	METHODS
23137	METHODS
23138	METHODS
23139	RESULTS
23140	METHODS
23141	RESULTS
23142	RESULTS
23143	RESULTS
23144	RESULTS
23145	RESULTS
23146	CONCLUSIONS
23147	BACKGROUND
23148	BACKGROUND
23149	METHODS
23150	RESULTS
23151	RESULTS
23152	RESULTS
23153	RESULTS
23154	CONCLUSIONS
23155	OBJECTIVE
23156	METHODS
23157	METHODS
23158	METHODS
23159	METHODS
23160	RESULTS
23161	RESULTS
23162	RESULTS
23163	RESULTS
23164	RESULTS
23165	CONCLUSIONS
23166	BACKGROUND
23167	OBJECTIVE
23168	OBJECTIVE
23169	METHODS
23170	METHODS
23171	METHODS
23172	RESULTS
23173	RESULTS
23174	RESULTS
23175	RESULTS
23176	CONCLUSIONS
23177	BACKGROUND
23178	BACKGROUND
23179	OBJECTIVE
23180	METHODS
23181	METHODS
23182	METHODS
23183	RESULTS
23184	RESULTS
23185	CONCLUSIONS
23186	RESULTS
23187	OBJECTIVE
23188	METHODS
23189	METHODS
23190	METHODS
23191	CONCLUSIONS
23192	RESULTS
23193	CONCLUSIONS
23194	BACKGROUND
23195	BACKGROUND
23196	METHODS
23197	METHODS
23198	METHODS
23199	METHODS
23200	METHODS
23201	METHODS
23202	RESULTS
23203	RESULTS
23204	RESULTS
23205	RESULTS
23206	RESULTS
23207	RESULTS
23208	RESULTS
23209	METHODS
23210	RESULTS
23211	BACKGROUND
23212	RESULTS
23213	CONCLUSIONS
23214	OBJECTIVE
23215	METHODS
23216	METHODS
23217	METHODS
23218	METHODS
23219	METHODS
23220	METHODS
23221	METHODS
23222	RESULTS
23223	RESULTS
23224	RESULTS
23225	OBJECTIVE
23226	METHODS
23227	METHODS
23228	METHODS
23229	RESULTS
23230	RESULTS
23231	RESULTS
23232	RESULTS
23233	RESULTS
23234	RESULTS
23235	CONCLUSIONS
23236	CONCLUSIONS
23237	BACKGROUND
23238	CONCLUSIONS
23239	METHODS
23240	METHODS
23241	METHODS
23242	METHODS
23243	METHODS
23244	CONCLUSIONS
23245	RESULTS
23246	RESULTS
23247	CONCLUSIONS
23248	CONCLUSIONS
23249	OBJECTIVE
23250	METHODS
23251	METHODS
23252	RESULTS
23253	RESULTS
23254	RESULTS
23255	CONCLUSIONS
23256	OBJECTIVE
23257	METHODS
23258	METHODS
23259	RESULTS
23260	RESULTS
23261	METHODS
23262	RESULTS
23263	RESULTS
23264	RESULTS
23265	CONCLUSIONS
23266	OBJECTIVE
23267	METHODS
23268	METHODS
23269	METHODS
23270	METHODS
23271	RESULTS
23272	RESULTS
23273	RESULTS
23274	CONCLUSIONS
23275	OBJECTIVE
23276	METHODS
23277	METHODS
23278	METHODS
23279	BACKGROUND
23280	METHODS
23281	RESULTS
23282	RESULTS
23283	RESULTS
23284	RESULTS
23285	RESULTS
23286	CONCLUSIONS
23287	BACKGROUND
23288	METHODS
23289	OBJECTIVE
23290	METHODS
23291	METHODS
23292	METHODS
23293	RESULTS
23294	RESULTS
23295	RESULTS
23296	RESULTS
23297	RESULTS
23298	RESULTS
23299	RESULTS
23300	RESULTS
23301	RESULTS
23302	CONCLUSIONS
23303	CONCLUSIONS
23304	CONCLUSIONS
23305	BACKGROUND
23306	BACKGROUND
23307	METHODS
23308	RESULTS
23309	RESULTS
23310	RESULTS
23311	RESULTS
23312	CONCLUSIONS
23313	CONCLUSIONS
23314	OBJECTIVE
23315	METHODS
23316	METHODS
23317	METHODS
23318	RESULTS
23319	RESULTS
23320	RESULTS
23321	CONCLUSIONS
23322	OBJECTIVE
23323	METHODS
23324	METHODS
23325	METHODS
23326	METHODS
23327	METHODS
23328	METHODS
23329	RESULTS
23330	RESULTS
23331	RESULTS
23332	CONCLUSIONS
23333	CONCLUSIONS
23334	OBJECTIVE
23335	OBJECTIVE
23336	RESULTS
23337	METHODS
23338	METHODS
23339	METHODS
23340	CONCLUSIONS
23341	RESULTS
23342	CONCLUSIONS
23343	CONCLUSIONS
23344	CONCLUSIONS
23345	CONCLUSIONS
23346	OBJECTIVE
23347	CONCLUSIONS
23348	METHODS
23349	OBJECTIVE
23350	RESULTS
23351	RESULTS
23352	RESULTS
23353	RESULTS
23354	CONCLUSIONS
23355	CONCLUSIONS
23356	BACKGROUND
23357	BACKGROUND
23358	METHODS
23359	METHODS
23360	METHODS
23361	RESULTS
23362	RESULTS
23363	RESULTS
23364	RESULTS
23365	CONCLUSIONS
23366	CONCLUSIONS
23367	BACKGROUND
23368	OBJECTIVE
23369	METHODS
23370	METHODS
23371	METHODS
23372	RESULTS
23373	RESULTS
23374	RESULTS
23375	RESULTS
23376	RESULTS
23377	CONCLUSIONS
23378	BACKGROUND
23379	BACKGROUND
23380	METHODS
23381	RESULTS
23382	RESULTS
23383	RESULTS
23384	CONCLUSIONS
23385	OBJECTIVE
23386	OBJECTIVE
23387	METHODS
23388	METHODS
23389	METHODS
23390	RESULTS
23391	RESULTS
23392	RESULTS
23393	CONCLUSIONS
23394	CONCLUSIONS
23395	OBJECTIVE
23396	METHODS
23397	METHODS
23398	RESULTS
23399	METHODS
23400	RESULTS
23401	RESULTS
23402	CONCLUSIONS
23403	CONCLUSIONS
23404	BACKGROUND
23405	BACKGROUND
23406	BACKGROUND
23407	BACKGROUND
23408	METHODS
23409	METHODS
23410	METHODS
23411	RESULTS
23412	RESULTS
23413	RESULTS
23414	METHODS
23415	RESULTS
23416	RESULTS
23417	RESULTS
23418	CONCLUSIONS
23419	BACKGROUND
23420	OBJECTIVE
23421	METHODS
23422	BACKGROUND
23423	BACKGROUND
23424	OBJECTIVE
23425	BACKGROUND
23426	OBJECTIVE
23427	CONCLUSIONS
23428	OBJECTIVE
23429	CONCLUSIONS
23430	OBJECTIVE
23431	METHODS
23432	METHODS
23433	METHODS
23434	METHODS
23435	METHODS
23436	RESULTS
23437	RESULTS
23438	RESULTS
23439	RESULTS
23440	RESULTS
23441	RESULTS
23442	CONCLUSIONS
23443	CONCLUSIONS
23444	OBJECTIVE
23445	METHODS
23446	METHODS
23447	RESULTS
23448	RESULTS
23449	CONCLUSIONS
23450	CONCLUSIONS
23451	CONCLUSIONS
23452	OBJECTIVE
23453	METHODS
23454	METHODS
23455	METHODS
23456	RESULTS
23457	RESULTS
23458	BACKGROUND
23459	METHODS
23460	METHODS
23461	METHODS
23462	METHODS
23463	METHODS
23464	CONCLUSIONS
23465	METHODS
23466	RESULTS
23467	RESULTS
23468	RESULTS
23469	RESULTS
23470	RESULTS
23471	RESULTS
23472	CONCLUSIONS
23473	CONCLUSIONS
23474	OBJECTIVE
23475	METHODS
23476	METHODS
23477	RESULTS
23478	RESULTS
23479	RESULTS
23480	RESULTS
23481	RESULTS
23482	RESULTS
23483	RESULTS
23484	RESULTS
23485	RESULTS
23486	BACKGROUND
23487	OBJECTIVE
23488	BACKGROUND
23489	METHODS
23490	METHODS
23491	METHODS
23492	RESULTS
23493	RESULTS
23494	RESULTS
23495	RESULTS
23496	RESULTS
23497	BACKGROUND
23498	BACKGROUND
23499	BACKGROUND
23500	BACKGROUND
23501	BACKGROUND
23502	OBJECTIVE
23503	METHODS
23504	RESULTS
23505	RESULTS
23506	RESULTS
23507	RESULTS
23508	CONCLUSIONS
23509	RESULTS
23510	CONCLUSIONS
23511	OBJECTIVE
23512	METHODS
23513	METHODS
23514	METHODS
23515	RESULTS
23516	RESULTS
23517	RESULTS
23518	CONCLUSIONS
23519	RESULTS
23520	METHODS
23521	BACKGROUND
23522	OBJECTIVE
23523	METHODS
23524	METHODS
23525	METHODS
23526	METHODS
23527	RESULTS
23528	RESULTS
23529	RESULTS
23530	RESULTS
23531	RESULTS
23532	RESULTS
23533	RESULTS
23534	CONCLUSIONS
23535	BACKGROUND
23536	OBJECTIVE
23537	METHODS
23538	METHODS
23539	METHODS
23540	RESULTS
23541	RESULTS
23542	RESULTS
23543	RESULTS
23544	RESULTS
23545	RESULTS
23546	BACKGROUND
23547	OBJECTIVE
23548	METHODS
23549	RESULTS
23550	RESULTS
23551	CONCLUSIONS
23552	CONCLUSIONS
23553	BACKGROUND
23554	OBJECTIVE
23555	METHODS
23556	METHODS
23557	METHODS
23558	RESULTS
23559	RESULTS
23560	RESULTS
23561	RESULTS
23562	RESULTS
23563	CONCLUSIONS
23564	CONCLUSIONS
23565	BACKGROUND
23566	OBJECTIVE
23567	METHODS
23568	RESULTS
23569	RESULTS
23570	RESULTS
23571	RESULTS
23572	RESULTS
23573	CONCLUSIONS
23574	BACKGROUND
23575	BACKGROUND
23576	METHODS
23577	METHODS
23578	METHODS
23579	METHODS
23580	RESULTS
23581	RESULTS
23582	RESULTS
23583	RESULTS
23584	CONCLUSIONS
23585	OBJECTIVE
23586	METHODS
23587	METHODS
23588	METHODS
23589	METHODS
23590	METHODS
23591	RESULTS
23592	RESULTS
23593	CONCLUSIONS
23594	CONCLUSIONS
23595	BACKGROUND
23596	BACKGROUND
23597	OBJECTIVE
23598	METHODS
23599	METHODS
23600	METHODS
23601	METHODS
23602	METHODS
23603	RESULTS
23604	RESULTS
23605	RESULTS
23606	CONCLUSIONS
23607	BACKGROUND
23608	BACKGROUND
23609	BACKGROUND
23610	METHODS
23611	METHODS
23612	METHODS
23613	RESULTS
23614	RESULTS
23615	RESULTS
23616	RESULTS
23617	RESULTS
23618	RESULTS
23619	RESULTS
23620	CONCLUSIONS
23621	CONCLUSIONS
23622	CONCLUSIONS
23623	BACKGROUND
23624	BACKGROUND
23625	METHODS
23626	METHODS
23627	METHODS
23628	METHODS
23629	RESULTS
23630	RESULTS
23631	RESULTS
23632	RESULTS
23633	CONCLUSIONS
23634	CONCLUSIONS
23635	BACKGROUND
23636	BACKGROUND
23637	BACKGROUND
23638	METHODS
23639	METHODS
23640	METHODS
23641	METHODS
23642	METHODS
23643	RESULTS
23644	RESULTS
23645	RESULTS
23646	RESULTS
23647	CONCLUSIONS
23648	CONCLUSIONS
23649	BACKGROUND
23650	OBJECTIVE
23651	METHODS
23652	RESULTS
23653	RESULTS
23654	CONCLUSIONS
23655	BACKGROUND
23656	BACKGROUND
23657	BACKGROUND
23658	METHODS
23659	METHODS
23660	METHODS
23661	RESULTS
23662	RESULTS
23663	RESULTS
23664	CONCLUSIONS
23665	CONCLUSIONS
23666	BACKGROUND
23667	BACKGROUND
23668	METHODS
23669	METHODS
23670	METHODS
23671	METHODS
23672	METHODS
23673	METHODS
23674	METHODS
23675	RESULTS
23676	RESULTS
23677	RESULTS
23678	RESULTS
23679	RESULTS
23680	RESULTS
23681	CONCLUSIONS
23682	BACKGROUND
23683	BACKGROUND
23684	METHODS
23685	METHODS
23686	METHODS
23687	RESULTS
23688	RESULTS
23689	RESULTS
23690	CONCLUSIONS
23691	CONCLUSIONS
23692	OBJECTIVE
23693	METHODS
23694	METHODS
23695	METHODS
23696	METHODS
23697	METHODS
23698	RESULTS
23699	RESULTS
23700	RESULTS
23701	CONCLUSIONS
23702	OBJECTIVE
23703	METHODS
23704	METHODS
23705	RESULTS
23706	RESULTS
23707	RESULTS
23708	CONCLUSIONS
23709	CONCLUSIONS
23710	OBJECTIVE
23711	METHODS
23712	METHODS
23713	METHODS
23714	METHODS
23715	RESULTS
23716	CONCLUSIONS
23717	RESULTS
23718	CONCLUSIONS
23719	BACKGROUND
23720	CONCLUSIONS
23721	OBJECTIVE
23722	METHODS
23723	METHODS
23724	METHODS
23725	METHODS
23726	METHODS
23727	METHODS
23728	METHODS
23729	RESULTS
23730	RESULTS
23731	CONCLUSIONS
23732	BACKGROUND
23733	OBJECTIVE
23734	CONCLUSIONS
23735	METHODS
23736	RESULTS
23737	CONCLUSIONS
23738	METHODS
23739	METHODS
23740	RESULTS
23741	RESULTS
23742	RESULTS
23743	CONCLUSIONS
23744	CONCLUSIONS
23745	BACKGROUND
23746	METHODS
23747	METHODS
23748	METHODS
23749	METHODS
23750	METHODS
23751	METHODS
23752	RESULTS
23753	RESULTS
23754	RESULTS
23755	CONCLUSIONS
23756	OBJECTIVE
23757	METHODS
23758	METHODS
23759	RESULTS
23760	RESULTS
23761	RESULTS
23762	RESULTS
23763	OBJECTIVE
23764	BACKGROUND
23765	METHODS
23766	METHODS
23767	RESULTS
23768	RESULTS
23769	RESULTS
23770	CONCLUSIONS
23771	CONCLUSIONS
23772	CONCLUSIONS
23773	OBJECTIVE
23774	METHODS
23775	METHODS
23776	METHODS
23777	METHODS
23778	METHODS
23779	METHODS
23780	RESULTS
23781	RESULTS
23782	RESULTS
23783	CONCLUSIONS
23784	RESULTS
23785	CONCLUSIONS
23786	OBJECTIVE
23787	METHODS
23788	METHODS
23789	METHODS
23790	METHODS
23791	METHODS
23792	METHODS
23793	RESULTS
23794	RESULTS
23795	RESULTS
23796	RESULTS
23797	CONCLUSIONS
23798	BACKGROUND
23799	OBJECTIVE
23800	METHODS
23801	METHODS
23802	METHODS
23803	RESULTS
23804	RESULTS
23805	CONCLUSIONS
23806	CONCLUSIONS
23807	BACKGROUND
23808	OBJECTIVE
23809	METHODS
23810	METHODS
23811	RESULTS
23812	METHODS
23813	METHODS
23814	METHODS
23815	METHODS
23816	METHODS
23817	METHODS
23818	METHODS
23819	METHODS
23820	METHODS
23821	RESULTS
23822	RESULTS
23823	RESULTS
23824	RESULTS
23825	CONCLUSIONS
23826	BACKGROUND
23827	BACKGROUND
23828	BACKGROUND
23829	BACKGROUND
23830	BACKGROUND
23831	OBJECTIVE
23832	METHODS
23833	METHODS
23834	RESULTS
23835	RESULTS
23836	CONCLUSIONS
23837	CONCLUSIONS
23838	OBJECTIVE
23839	METHODS
23840	METHODS
23841	METHODS
23842	METHODS
23843	METHODS
23844	RESULTS
23845	RESULTS
23846	CONCLUSIONS
23847	CONCLUSIONS
23848	OBJECTIVE
23849	OBJECTIVE
23850	METHODS
23851	METHODS
23852	METHODS
23853	METHODS
23854	METHODS
23855	METHODS
23856	RESULTS
23857	RESULTS
23858	RESULTS
23859	CONCLUSIONS
23860	CONCLUSIONS
23861	OBJECTIVE
23862	METHODS
23863	METHODS
23864	METHODS
23865	METHODS
23866	METHODS
23867	RESULTS
23868	RESULTS
23869	RESULTS
23870	RESULTS
23871	RESULTS
23872	RESULTS
23873	CONCLUSIONS
23874	BACKGROUND
23875	BACKGROUND
23876	BACKGROUND
23877	METHODS
23878	METHODS
23879	METHODS
23880	METHODS
23881	RESULTS
23882	RESULTS
23883	RESULTS
23884	RESULTS
23885	RESULTS
23886	RESULTS
23887	CONCLUSIONS
23888	CONCLUSIONS
23889	OBJECTIVE
23890	METHODS
23891	RESULTS
23892	RESULTS
23893	RESULTS
23894	RESULTS
23895	RESULTS
23896	CONCLUSIONS
23897	OBJECTIVE
23898	BACKGROUND
23899	BACKGROUND
23900	METHODS
23901	METHODS
23902	METHODS
23903	METHODS
23904	METHODS
23905	RESULTS
23906	RESULTS
23907	RESULTS
23908	CONCLUSIONS
23909	BACKGROUND
23910	OBJECTIVE
23911	METHODS
23912	METHODS
23913	RESULTS
23914	RESULTS
23915	RESULTS
23916	RESULTS
23917	CONCLUSIONS
23918	CONCLUSIONS
23919	CONCLUSIONS
23920	OBJECTIVE
23921	METHODS
23922	METHODS
23923	METHODS
23924	RESULTS
23925	RESULTS
23926	RESULTS
23927	CONCLUSIONS
23928	CONCLUSIONS
23929	OBJECTIVE
23930	METHODS
23931	METHODS
23932	RESULTS
23933	RESULTS
23934	METHODS
23935	METHODS
23936	METHODS
23937	RESULTS
23938	RESULTS
23939	RESULTS
23940	CONCLUSIONS
23941	OBJECTIVE
23942	METHODS
23943	METHODS
23944	METHODS
23945	METHODS
23946	METHODS
23947	RESULTS
23948	RESULTS
23949	RESULTS
23950	CONCLUSIONS
23951	CONCLUSIONS
23952	CONCLUSIONS
23953	BACKGROUND
23954	BACKGROUND
23955	BACKGROUND
23956	METHODS
23957	METHODS
23958	METHODS
23959	METHODS
23960	METHODS
23961	METHODS
23962	METHODS
23963	METHODS
23964	CONCLUSIONS
23965	CONCLUSIONS
23966	BACKGROUND
23967	OBJECTIVE
23968	METHODS
23969	METHODS
23970	RESULTS
23971	RESULTS
23972	RESULTS
23973	CONCLUSIONS
23974	CONCLUSIONS
23975	CONCLUSIONS
23976	CONCLUSIONS
23977	BACKGROUND
23978	BACKGROUND
23979	OBJECTIVE
23980	METHODS
23981	METHODS
23982	METHODS
23983	METHODS
23984	METHODS
23985	METHODS
23986	METHODS
23987	RESULTS
23988	RESULTS
23989	RESULTS
23990	RESULTS
23991	RESULTS
23992	RESULTS
23993	RESULTS
23994	CONCLUSIONS
23995	OBJECTIVE
23996	METHODS
23997	METHODS
23998	METHODS
23999	METHODS
24000	RESULTS
24001	RESULTS
24002	CONCLUSIONS
24003	BACKGROUND
24004	OBJECTIVE
24005	METHODS
24006	METHODS
24007	METHODS
24008	RESULTS
24009	RESULTS
24010	RESULTS
24011	RESULTS
24012	RESULTS
24013	RESULTS
24014	CONCLUSIONS
24015	OBJECTIVE
24016	METHODS
24017	METHODS
24018	METHODS
24019	METHODS
24020	RESULTS
24021	RESULTS
24022	RESULTS
24023	CONCLUSIONS
24024	RESULTS
24025	OBJECTIVE
24026	METHODS
24027	METHODS
24028	METHODS
24029	METHODS
24030	RESULTS
24031	CONCLUSIONS
24032	OBJECTIVE
24033	METHODS
24034	METHODS
24035	METHODS
24036	METHODS
24037	METHODS
24038	METHODS
24039	METHODS
24040	RESULTS
24041	RESULTS
24042	RESULTS
24043	RESULTS
24044	RESULTS
24045	RESULTS
24046	RESULTS
24047	RESULTS
24048	RESULTS
24049	CONCLUSIONS
24050	CONCLUSIONS
24051	CONCLUSIONS
24052	BACKGROUND
24053	OBJECTIVE
24054	METHODS
24055	METHODS
24056	METHODS
24057	METHODS
24058	METHODS
24059	METHODS
24060	RESULTS
24061	RESULTS
24062	RESULTS
24063	CONCLUSIONS
24064	BACKGROUND
24065	OBJECTIVE
24066	METHODS
24067	METHODS
24068	METHODS
24069	RESULTS
24070	RESULTS
24071	METHODS
24072	RESULTS
24073	RESULTS
24074	CONCLUSIONS
24075	BACKGROUND
24076	BACKGROUND
24077	METHODS
24078	METHODS
24079	METHODS
24080	METHODS
24081	METHODS
24082	RESULTS
24083	RESULTS
24084	RESULTS
24085	RESULTS
24086	RESULTS
24087	CONCLUSIONS
24088	BACKGROUND
24089	OBJECTIVE
24090	METHODS
24091	METHODS
24092	METHODS
24093	RESULTS
24094	RESULTS
24095	RESULTS
24096	RESULTS
24097	RESULTS
24098	RESULTS
24099	CONCLUSIONS
24100	OBJECTIVE
24101	METHODS
24102	METHODS
24103	METHODS
24104	METHODS
24105	METHODS
24106	RESULTS
24107	RESULTS
24108	RESULTS
24109	CONCLUSIONS
24110	OBJECTIVE
24111	METHODS
24112	METHODS
24113	METHODS
24114	RESULTS
24115	RESULTS
24116	RESULTS
24117	CONCLUSIONS
24118	RESULTS
24119	RESULTS
24120	CONCLUSIONS
24121	CONCLUSIONS
24122	CONCLUSIONS
24123	BACKGROUND
24124	OBJECTIVE
24125	METHODS
24126	METHODS
24127	METHODS
24128	METHODS
24129	RESULTS
24130	RESULTS
24131	RESULTS
24132	RESULTS
24133	CONCLUSIONS
24134	CONCLUSIONS
24135	BACKGROUND
24136	BACKGROUND
24137	BACKGROUND
24138	METHODS
24139	METHODS
24140	METHODS
24141	METHODS
24142	METHODS
24143	METHODS
24144	METHODS
24145	RESULTS
24146	RESULTS
24147	RESULTS
24148	RESULTS
24149	CONCLUSIONS
24150	CONCLUSIONS
24151	CONCLUSIONS
24152	BACKGROUND
24153	BACKGROUND
24154	OBJECTIVE
24155	RESULTS
24156	BACKGROUND
24157	BACKGROUND
24158	OBJECTIVE
24159	METHODS
24160	METHODS
24161	METHODS
24162	METHODS
24163	METHODS
24164	METHODS
24165	RESULTS
24166	RESULTS
24167	CONCLUSIONS
24168	RESULTS
24169	RESULTS
24170	RESULTS
24171	CONCLUSIONS
24172	BACKGROUND
24173	OBJECTIVE
24174	METHODS
24175	METHODS
24176	METHODS
24177	METHODS
24178	RESULTS
24179	RESULTS
24180	RESULTS
24181	RESULTS
24182	RESULTS
24183	CONCLUSIONS
24184	BACKGROUND
24185	METHODS
24186	METHODS
24187	METHODS
24188	RESULTS
24189	RESULTS
24190	RESULTS
24191	CONCLUSIONS
24192	OBJECTIVE
24193	METHODS
24194	METHODS
24195	RESULTS
24196	RESULTS
24197	RESULTS
24198	RESULTS
24199	RESULTS
24200	RESULTS
24201	RESULTS
24202	RESULTS
24203	RESULTS
24204	OBJECTIVE
24205	OBJECTIVE
24206	METHODS
24207	METHODS
24208	RESULTS
24209	RESULTS
24210	RESULTS
24211	RESULTS
24212	RESULTS
24213	CONCLUSIONS
24214	OBJECTIVE
24215	BACKGROUND
24216	BACKGROUND
24217	METHODS
24218	RESULTS
24219	METHODS
24220	RESULTS
24221	RESULTS
24222	RESULTS
24223	RESULTS
24224	RESULTS
24225	CONCLUSIONS
24226	CONCLUSIONS
24227	OBJECTIVE
24228	METHODS
24229	METHODS
24230	METHODS
24231	RESULTS
24232	RESULTS
24233	RESULTS
24234	RESULTS
24235	CONCLUSIONS
24236	CONCLUSIONS
24237	BACKGROUND
24238	OBJECTIVE
24239	METHODS
24240	METHODS
24241	METHODS
24242	METHODS
24243	RESULTS
24244	RESULTS
24245	RESULTS
24246	RESULTS
24247	CONCLUSIONS
24248	BACKGROUND
24249	OBJECTIVE
24250	METHODS
24251	METHODS
24252	METHODS
24253	RESULTS
24254	RESULTS
24255	RESULTS
24256	CONCLUSIONS
24257	BACKGROUND
24258	CONCLUSIONS
24259	METHODS
24260	METHODS
24261	METHODS
24262	METHODS
24263	RESULTS
24264	RESULTS
24265	RESULTS
24266	RESULTS
24267	RESULTS
24268	CONCLUSIONS
24269	BACKGROUND
24270	BACKGROUND
24271	METHODS
24272	RESULTS
24273	RESULTS
24274	RESULTS
24275	RESULTS
24276	RESULTS
24277	CONCLUSIONS
24278	BACKGROUND
24279	BACKGROUND
24280	BACKGROUND
24281	BACKGROUND
24282	METHODS
24283	RESULTS
24284	RESULTS
24285	CONCLUSIONS
24286	BACKGROUND
24287	BACKGROUND
24288	METHODS
24289	METHODS
24290	METHODS
24291	METHODS
24292	METHODS
24293	METHODS
24294	CONCLUSIONS
24295	BACKGROUND
24296	BACKGROUND
24297	METHODS
24298	METHODS
24299	METHODS
24300	RESULTS
24301	RESULTS
24302	RESULTS
24303	RESULTS
24304	CONCLUSIONS
24305	OBJECTIVE
24306	METHODS
24307	METHODS
24308	RESULTS
24309	METHODS
24310	RESULTS
24311	RESULTS
24312	RESULTS
24313	RESULTS
24314	RESULTS
24315	RESULTS
24316	RESULTS
24317	RESULTS
24318	CONCLUSIONS
24319	CONCLUSIONS
24320	BACKGROUND
24321	METHODS
24322	RESULTS
24323	METHODS
24324	METHODS
24325	METHODS
24326	METHODS
24327	RESULTS
24328	RESULTS
24329	RESULTS
24330	RESULTS
24331	RESULTS
24332	RESULTS
24333	RESULTS
24334	RESULTS
24335	BACKGROUND
24336	BACKGROUND
24337	METHODS
24338	METHODS
24339	METHODS
24340	RESULTS
24341	RESULTS
24342	RESULTS
24343	RESULTS
24344	RESULTS
24345	RESULTS
24346	RESULTS
24347	CONCLUSIONS
24348	CONCLUSIONS
24349	CONCLUSIONS
24350	OBJECTIVE
24351	METHODS
24352	METHODS
24353	CONCLUSIONS
24354	RESULTS
24355	RESULTS
24356	RESULTS
24357	RESULTS
24358	CONCLUSIONS
24359	CONCLUSIONS
24360	OBJECTIVE
24361	OBJECTIVE
24362	METHODS
24363	RESULTS
24364	RESULTS
24365	RESULTS
24366	RESULTS
24367	RESULTS
24368	CONCLUSIONS
24369	BACKGROUND
24370	BACKGROUND
24371	BACKGROUND
24372	METHODS
24373	METHODS
24374	METHODS
24375	METHODS
24376	RESULTS
24377	RESULTS
24378	RESULTS
24379	RESULTS
24380	CONCLUSIONS
24381	CONCLUSIONS
24382	OBJECTIVE
24383	METHODS
24384	METHODS
24385	METHODS
24386	RESULTS
24387	RESULTS
24388	RESULTS
24389	CONCLUSIONS
24390	BACKGROUND
24391	BACKGROUND
24392	BACKGROUND
24393	CONCLUSIONS
24394	METHODS
24395	METHODS
24396	METHODS
24397	METHODS
24398	METHODS
24399	CONCLUSIONS
24400	CONCLUSIONS
24401	BACKGROUND
24402	METHODS
24403	METHODS
24404	RESULTS
24405	RESULTS
24406	RESULTS
24407	RESULTS
24408	RESULTS
24409	RESULTS
24410	CONCLUSIONS
24411	BACKGROUND
24412	OBJECTIVE
24413	METHODS
24414	RESULTS
24415	METHODS
24416	METHODS
24417	RESULTS
24418	RESULTS
24419	CONCLUSIONS
24420	CONCLUSIONS
24421	BACKGROUND
24422	CONCLUSIONS
24423	METHODS
24424	METHODS
24425	METHODS
24426	METHODS
24427	RESULTS
24428	METHODS
24429	RESULTS
24430	RESULTS
24431	RESULTS
24432	CONCLUSIONS
24433	OBJECTIVE
24434	METHODS
24435	METHODS
24436	METHODS
24437	METHODS
24438	RESULTS
24439	RESULTS
24440	RESULTS
24441	RESULTS
24442	CONCLUSIONS
24443	CONCLUSIONS
24444	BACKGROUND
24445	BACKGROUND
24446	METHODS
24447	METHODS
24448	METHODS
24449	RESULTS
24450	RESULTS
24451	CONCLUSIONS
24452	BACKGROUND
24453	BACKGROUND
24454	OBJECTIVE
24455	METHODS
24456	METHODS
24457	RESULTS
24458	RESULTS
24459	CONCLUSIONS
24460	RESULTS
24461	CONCLUSIONS
24462	OBJECTIVE
24463	METHODS
24464	METHODS
24465	METHODS
24466	METHODS
24467	METHODS
24468	METHODS
24469	RESULTS
24470	RESULTS
24471	RESULTS
24472	RESULTS
24473	CONCLUSIONS
24474	RESULTS
24475	RESULTS
24476	RESULTS
24477	CONCLUSIONS
24478	CONCLUSIONS
24479	CONCLUSIONS
24480	BACKGROUND
24481	METHODS
24482	METHODS
24483	METHODS
24484	METHODS
24485	RESULTS
24486	RESULTS
24487	RESULTS
24488	RESULTS
24489	CONCLUSIONS
24490	BACKGROUND
24491	BACKGROUND
24492	OBJECTIVE
24493	METHODS
24494	METHODS
24495	METHODS
24496	RESULTS
24497	CONCLUSIONS
24498	CONCLUSIONS
24499	OBJECTIVE
24500	METHODS
24501	METHODS
24502	RESULTS
24503	METHODS
24504	METHODS
24505	METHODS
24506	RESULTS
24507	RESULTS
24508	RESULTS
24509	METHODS
24510	METHODS
24511	RESULTS
24512	CONCLUSIONS
24513	BACKGROUND
24514	BACKGROUND
24515	BACKGROUND
24516	METHODS
24517	METHODS
24518	METHODS
24519	RESULTS
24520	RESULTS
24521	RESULTS
24522	METHODS
24523	BACKGROUND
24524	CONCLUSIONS
24525	BACKGROUND
24526	METHODS
24527	METHODS
24528	METHODS
24529	METHODS
24530	RESULTS
24531	RESULTS
24532	RESULTS
24533	RESULTS
24534	RESULTS
24535	RESULTS
24536	CONCLUSIONS
24537	CONCLUSIONS
24538	OBJECTIVE
24539	METHODS
24540	RESULTS
24541	RESULTS
24542	RESULTS
24543	CONCLUSIONS
24544	CONCLUSIONS
24545	CONCLUSIONS
24546	BACKGROUND
24547	BACKGROUND
24548	OBJECTIVE
24549	METHODS
24550	METHODS
24551	RESULTS
24552	RESULTS
24553	RESULTS
24554	RESULTS
24555	CONCLUSIONS
24556	CONCLUSIONS
24557	CONCLUSIONS
24558	CONCLUSIONS
24559	CONCLUSIONS
24560	BACKGROUND
24561	BACKGROUND
24562	BACKGROUND
24563	METHODS
24564	METHODS
24565	METHODS
24566	METHODS
24567	RESULTS
24568	RESULTS
24569	CONCLUSIONS
24570	BACKGROUND
24571	OBJECTIVE
24572	METHODS
24573	METHODS
24574	METHODS
24575	METHODS
24576	RESULTS
24577	RESULTS
24578	CONCLUSIONS
24579	CONCLUSIONS
24580	OBJECTIVE
24581	METHODS
24582	METHODS
24583	METHODS
24584	METHODS
24585	METHODS
24586	METHODS
24587	RESULTS
24588	RESULTS
24589	RESULTS
24590	RESULTS
24591	RESULTS
24592	RESULTS
24593	CONCLUSIONS
24594	RESULTS
24595	OBJECTIVE
24596	RESULTS
24597	METHODS
24598	METHODS
24599	METHODS
24600	METHODS
24601	METHODS
24602	METHODS
24603	RESULTS
24604	RESULTS
24605	RESULTS
24606	RESULTS
24607	RESULTS
24608	RESULTS
24609	CONCLUSIONS
24610	CONCLUSIONS
24611	OBJECTIVE
24612	METHODS
24613	RESULTS
24614	RESULTS
24615	RESULTS
24616	RESULTS
24617	CONCLUSIONS
24618	OBJECTIVE
24619	METHODS
24620	METHODS
24621	METHODS
24622	METHODS
24623	METHODS
24624	RESULTS
24625	METHODS
24626	RESULTS
24627	RESULTS
24628	RESULTS
24629	RESULTS
24630	RESULTS
24631	RESULTS
24632	RESULTS
24633	CONCLUSIONS
24634	RESULTS
24635	RESULTS
24636	CONCLUSIONS
24637	BACKGROUND
24638	OBJECTIVE
24639	METHODS
24640	RESULTS
24641	RESULTS
24642	RESULTS
24643	RESULTS
24644	RESULTS
24645	RESULTS
24646	RESULTS
24647	RESULTS
24648	RESULTS
24649	CONCLUSIONS
24650	CONCLUSIONS
24651	BACKGROUND
24652	OBJECTIVE
24653	METHODS
24654	METHODS
24655	METHODS
24656	METHODS
24657	METHODS
24658	RESULTS
24659	RESULTS
24660	CONCLUSIONS
24661	BACKGROUND
24662	OBJECTIVE
24663	METHODS
24664	METHODS
24665	METHODS
24666	RESULTS
24667	RESULTS
24668	RESULTS
24669	RESULTS
24670	RESULTS
24671	RESULTS
24672	CONCLUSIONS
24673	BACKGROUND
24674	BACKGROUND
24675	METHODS
24676	METHODS
24677	METHODS
24678	RESULTS
24679	RESULTS
24680	RESULTS
24681	RESULTS
24682	RESULTS
24683	METHODS
24684	CONCLUSIONS
24685	CONCLUSIONS
24686	RESULTS
24687	BACKGROUND
24688	BACKGROUND
24689	OBJECTIVE
24690	METHODS
24691	METHODS
24692	METHODS
24693	RESULTS
24694	METHODS
24695	METHODS
24696	METHODS
24697	METHODS
24698	METHODS
24699	RESULTS
24700	RESULTS
24701	RESULTS
24702	RESULTS
24703	CONCLUSIONS
24704	RESULTS
24705	CONCLUSIONS
24706	OBJECTIVE
24707	METHODS
24708	METHODS
24709	METHODS
24710	METHODS
24711	METHODS
24712	METHODS
24713	RESULTS
24714	CONCLUSIONS
24715	CONCLUSIONS
24716	OBJECTIVE
24717	METHODS
24718	METHODS
24719	METHODS
24720	METHODS
24721	RESULTS
24722	RESULTS
24723	RESULTS
24724	RESULTS
24725	CONCLUSIONS
24726	RESULTS
24727	BACKGROUND
24728	BACKGROUND
24729	METHODS
24730	METHODS
24731	METHODS
24732	METHODS
24733	RESULTS
24734	RESULTS
24735	RESULTS
24736	RESULTS
24737	RESULTS
24738	CONCLUSIONS
24739	CONCLUSIONS
24740	BACKGROUND
24741	BACKGROUND
24742	BACKGROUND
24743	OBJECTIVE
24744	METHODS
24745	RESULTS
24746	RESULTS
24747	RESULTS
24748	RESULTS
24749	RESULTS
24750	RESULTS
24751	CONCLUSIONS
24752	BACKGROUND
24753	CONCLUSIONS
24754	OBJECTIVE
24755	METHODS
24756	METHODS
24757	METHODS
24758	METHODS
24759	RESULTS
24760	RESULTS
24761	RESULTS
24762	RESULTS
24763	RESULTS
24764	RESULTS
24765	CONCLUSIONS
24766	OBJECTIVE
24767	METHODS
24768	METHODS
24769	METHODS
24770	METHODS
24771	RESULTS
24772	RESULTS
24773	RESULTS
24774	RESULTS
24775	RESULTS
24776	CONCLUSIONS
24777	CONCLUSIONS
24778	BACKGROUND
24779	OBJECTIVE
24780	METHODS
24781	METHODS
24782	METHODS
24783	METHODS
24784	RESULTS
24785	RESULTS
24786	CONCLUSIONS
24787	CONCLUSIONS
24788	BACKGROUND
24789	BACKGROUND
24790	BACKGROUND
24791	OBJECTIVE
24792	CONCLUSIONS
24793	METHODS
24794	METHODS
24795	METHODS
24796	METHODS
24797	METHODS
24798	METHODS
24799	METHODS
24800	METHODS
24801	CONCLUSIONS
24802	CONCLUSIONS
24803	CONCLUSIONS
24804	BACKGROUND
24805	OBJECTIVE
24806	METHODS
24807	METHODS
24808	METHODS
24809	METHODS
24810	METHODS
24811	METHODS
24812	METHODS
24813	RESULTS
24814	RESULTS
24815	RESULTS
24816	RESULTS
24817	CONCLUSIONS
24818	CONCLUSIONS
24819	BACKGROUND
24820	OBJECTIVE
24821	METHODS
24822	METHODS
24823	METHODS
24824	BACKGROUND
24825	RESULTS
24826	RESULTS
24827	RESULTS
24828	CONCLUSIONS
24829	RESULTS
24830	RESULTS
24831	CONCLUSIONS
24832	OBJECTIVE
24833	METHODS
24834	METHODS
24835	METHODS
24836	METHODS
24837	METHODS
24838	RESULTS
24839	RESULTS
24840	RESULTS
24841	RESULTS
24842	CONCLUSIONS
24843	CONCLUSIONS
24844	CONCLUSIONS
24845	OBJECTIVE
24846	METHODS
24847	METHODS
24848	METHODS
24849	RESULTS
24850	RESULTS
24851	RESULTS
24852	RESULTS
24853	CONCLUSIONS
24854	RESULTS
24855	CONCLUSIONS
24856	BACKGROUND
24857	BACKGROUND
24858	CONCLUSIONS
24859	METHODS
24860	METHODS
24861	RESULTS
24862	RESULTS
24863	RESULTS
24864	RESULTS
24865	CONCLUSIONS
24866	CONCLUSIONS
24867	CONCLUSIONS
24868	OBJECTIVE
24869	METHODS
24870	METHODS
24871	METHODS
24872	METHODS
24873	METHODS
24874	METHODS
24875	METHODS
24876	METHODS
24877	METHODS
24878	RESULTS
24879	RESULTS
24880	RESULTS
24881	RESULTS
24882	RESULTS
24883	CONCLUSIONS
24884	CONCLUSIONS
24885	BACKGROUND
24886	BACKGROUND
24887	OBJECTIVE
24888	METHODS
24889	METHODS
24890	RESULTS
24891	CONCLUSIONS
24892	RESULTS
24893	RESULTS
24894	RESULTS
24895	RESULTS
24896	CONCLUSIONS
24897	BACKGROUND
24898	BACKGROUND
24899	OBJECTIVE
24900	METHODS
24901	RESULTS
24902	METHODS
24903	RESULTS
24904	RESULTS
24905	RESULTS
24906	CONCLUSIONS
24907	OBJECTIVE
24908	METHODS
24909	RESULTS
24910	RESULTS
24911	RESULTS
24912	RESULTS
24913	RESULTS
24914	RESULTS
24915	RESULTS
24916	RESULTS
24917	BACKGROUND
24918	OBJECTIVE
24919	METHODS
24920	METHODS
24921	RESULTS
24922	RESULTS
24923	RESULTS
24924	RESULTS
24925	CONCLUSIONS
24926	CONCLUSIONS
24927	BACKGROUND
24928	OBJECTIVE
24929	METHODS
24930	METHODS
24931	METHODS
24932	RESULTS
24933	RESULTS
24934	RESULTS
24935	RESULTS
24936	RESULTS
24937	CONCLUSIONS
24938	CONCLUSIONS
24939	CONCLUSIONS
24940	OBJECTIVE
24941	METHODS
24942	METHODS
24943	METHODS
24944	METHODS
24945	RESULTS
24946	RESULTS
24947	RESULTS
24948	RESULTS
24949	OBJECTIVE
24950	METHODS
24951	METHODS
24952	RESULTS
24953	RESULTS
24954	RESULTS
24955	CONCLUSIONS
24956	BACKGROUND
24957	BACKGROUND
24958	OBJECTIVE
24959	METHODS
24960	METHODS
24961	METHODS
24962	METHODS
24963	METHODS
24964	METHODS
24965	RESULTS
24966	RESULTS
24967	RESULTS
24968	RESULTS
24969	RESULTS
24970	CONCLUSIONS
24971	BACKGROUND
24972	OBJECTIVE
24973	METHODS
24974	METHODS
24975	METHODS
24976	CONCLUSIONS
24977	RESULTS
24978	RESULTS
24979	RESULTS
24980	RESULTS
24981	RESULTS
24982	CONCLUSIONS
24983	CONCLUSIONS
24984	BACKGROUND
24985	BACKGROUND
24986	METHODS
24987	METHODS
24988	METHODS
24989	METHODS
24990	METHODS
24991	METHODS
24992	METHODS
24993	RESULTS
24994	RESULTS
24995	RESULTS
24996	RESULTS
24997	RESULTS
24998	CONCLUSIONS
24999	BACKGROUND
25000	BACKGROUND
25001	METHODS
25002	METHODS
25003	METHODS
25004	METHODS
25005	METHODS
25006	METHODS
25007	METHODS
25008	METHODS
25009	RESULTS
25010	RESULTS
25011	RESULTS
25012	RESULTS
25013	RESULTS
25014	CONCLUSIONS
25015	CONCLUSIONS
25016	OBJECTIVE
25017	BACKGROUND
25018	CONCLUSIONS
25019	METHODS
25020	METHODS
25021	RESULTS
25022	RESULTS
25023	RESULTS
25024	CONCLUSIONS
25025	OBJECTIVE
25026	BACKGROUND
25027	BACKGROUND
25028	METHODS
25029	METHODS
25030	RESULTS
25031	RESULTS
25032	RESULTS
25033	RESULTS
25034	CONCLUSIONS
25035	BACKGROUND
25036	BACKGROUND
25037	OBJECTIVE
25038	METHODS
25039	METHODS
25040	METHODS
25041	RESULTS
25042	RESULTS
25043	BACKGROUND
25044	CONCLUSIONS
25045	BACKGROUND
25046	BACKGROUND
25047	METHODS
25048	OBJECTIVE
25049	METHODS
25050	RESULTS
25051	RESULTS
25052	RESULTS
25053	RESULTS
25054	RESULTS
25055	BACKGROUND
25056	CONCLUSIONS
25057	BACKGROUND
25058	METHODS
25059	METHODS
25060	METHODS
25061	METHODS
25062	RESULTS
25063	RESULTS
25064	CONCLUSIONS
25065	RESULTS
25066	BACKGROUND
25067	CONCLUSIONS
25068	BACKGROUND
25069	OBJECTIVE
25070	BACKGROUND
25071	METHODS
25072	METHODS
25073	METHODS
25074	RESULTS
25075	RESULTS
25076	CONCLUSIONS
25077	CONCLUSIONS
25078	CONCLUSIONS
25079	OBJECTIVE
25080	METHODS
25081	METHODS
25082	METHODS
25083	METHODS
25084	RESULTS
25085	RESULTS
25086	RESULTS
25087	RESULTS
25088	CONCLUSIONS
25089	BACKGROUND
25090	BACKGROUND
25091	BACKGROUND
25092	BACKGROUND
25093	OBJECTIVE
25094	METHODS
25095	METHODS
25096	METHODS
25097	METHODS
25098	METHODS
25099	METHODS
25100	METHODS
25101	BACKGROUND
25102	BACKGROUND
25103	BACKGROUND
25104	BACKGROUND
25105	OBJECTIVE
25106	METHODS
25107	METHODS
25108	METHODS
25109	RESULTS
25110	RESULTS
25111	RESULTS
25112	METHODS
25113	CONCLUSIONS
25114	BACKGROUND
25115	OBJECTIVE
25116	METHODS
25117	METHODS
25118	RESULTS
25119	RESULTS
25120	RESULTS
25121	RESULTS
25122	RESULTS
25123	CONCLUSIONS
25124	OBJECTIVE
25125	METHODS
25126	METHODS
25127	METHODS
25128	METHODS
25129	METHODS
25130	METHODS
25131	METHODS
25132	METHODS
25133	RESULTS
25134	RESULTS
25135	CONCLUSIONS
25136	BACKGROUND
25137	OBJECTIVE
25138	METHODS
25139	METHODS
25140	METHODS
25141	METHODS
25142	METHODS
25143	METHODS
25144	RESULTS
25145	RESULTS
25146	RESULTS
25147	CONCLUSIONS
25148	RESULTS
25149	OBJECTIVE
25150	BACKGROUND
25151	METHODS
25152	METHODS
25153	METHODS
25154	METHODS
25155	METHODS
25156	METHODS
25157	METHODS
25158	RESULTS
25159	CONCLUSIONS
25160	RESULTS
25161	RESULTS
25162	RESULTS
25163	RESULTS
25164	RESULTS
25165	CONCLUSIONS
25166	CONCLUSIONS
25167	OBJECTIVE
25168	OBJECTIVE
25169	METHODS
25170	METHODS
25171	METHODS
25172	METHODS
25173	RESULTS
25174	RESULTS
25175	RESULTS
25176	RESULTS
25177	RESULTS
25178	RESULTS
25179	RESULTS
25180	RESULTS
25181	CONCLUSIONS
25182	RESULTS
25183	RESULTS
25184	OBJECTIVE
25185	METHODS
25186	METHODS
25187	METHODS
25188	RESULTS
25189	RESULTS
25190	RESULTS
25191	CONCLUSIONS
25192	RESULTS
25193	BACKGROUND
25194	METHODS
25195	METHODS
25196	METHODS
25197	METHODS
25198	RESULTS
25199	RESULTS
25200	RESULTS
25201	CONCLUSIONS
25202	OBJECTIVE
25203	METHODS
25204	METHODS
25205	METHODS
25206	METHODS
25207	METHODS
25208	METHODS
25209	METHODS
25210	RESULTS
25211	RESULTS
25212	CONCLUSIONS
25213	BACKGROUND
25214	CONCLUSIONS
25215	CONCLUSIONS
25216	OBJECTIVE
25217	OBJECTIVE
25218	OBJECTIVE
25219	METHODS
25220	METHODS
25221	METHODS
25222	RESULTS
25223	RESULTS
25224	RESULTS
25225	RESULTS
25226	RESULTS
25227	CONCLUSIONS
25228	BACKGROUND
25229	BACKGROUND
25230	BACKGROUND
25231	METHODS
25232	METHODS
25233	METHODS
25234	METHODS
25235	METHODS
25236	METHODS
25237	RESULTS
25238	RESULTS
25239	RESULTS
25240	RESULTS
25241	RESULTS
25242	CONCLUSIONS
25243	CONCLUSIONS
25244	OBJECTIVE
25245	METHODS
25246	METHODS
25247	METHODS
25248	METHODS
25249	METHODS
25250	METHODS
25251	METHODS
25252	METHODS
25253	RESULTS
25254	RESULTS
25255	RESULTS
25256	CONCLUSIONS
25257	BACKGROUND
25258	BACKGROUND
25259	METHODS
25260	METHODS
25261	METHODS
25262	RESULTS
25263	RESULTS
25264	RESULTS
25265	CONCLUSIONS
25266	BACKGROUND
25267	CONCLUSIONS
25268	METHODS
25269	METHODS
25270	RESULTS
25271	RESULTS
25272	RESULTS
25273	CONCLUSIONS
25274	CONCLUSIONS
25275	BACKGROUND
25276	BACKGROUND
25277	BACKGROUND
25278	METHODS
25279	METHODS
25280	METHODS
25281	METHODS
25282	METHODS
25283	RESULTS
25284	RESULTS
25285	RESULTS
25286	CONCLUSIONS
25287	CONCLUSIONS
25288	BACKGROUND
25289	BACKGROUND
25290	METHODS
25291	METHODS
25292	RESULTS
25293	RESULTS
25294	RESULTS
25295	CONCLUSIONS
25296	CONCLUSIONS
25297	OBJECTIVE
25298	OBJECTIVE
25299	METHODS
25300	METHODS
25301	METHODS
25302	METHODS
25303	RESULTS
25304	RESULTS
25305	RESULTS
25306	RESULTS
25307	CONCLUSIONS
25308	CONCLUSIONS
25309	BACKGROUND
25310	BACKGROUND
25311	METHODS
25312	RESULTS
25313	RESULTS
25314	RESULTS
25315	RESULTS
25316	CONCLUSIONS
25317	CONCLUSIONS
25318	CONCLUSIONS
25319	BACKGROUND
25320	BACKGROUND
25321	BACKGROUND
25322	BACKGROUND
25323	BACKGROUND
25324	BACKGROUND
25325	METHODS
25326	METHODS
25327	METHODS
25328	METHODS
25329	METHODS
25330	METHODS
25331	CONCLUSIONS
25332	CONCLUSIONS
25333	CONCLUSIONS
25334	BACKGROUND
25335	BACKGROUND
25336	BACKGROUND
25337	BACKGROUND
25338	METHODS
25339	METHODS
25340	METHODS
25341	METHODS
25342	RESULTS
25343	RESULTS
25344	RESULTS
25345	RESULTS
25346	RESULTS
25347	CONCLUSIONS
25348	BACKGROUND
25349	OBJECTIVE
25350	METHODS
25351	METHODS
25352	METHODS
25353	METHODS
25354	RESULTS
25355	RESULTS
25356	RESULTS
25357	CONCLUSIONS
25358	CONCLUSIONS
25359	BACKGROUND
25360	BACKGROUND
25361	METHODS
25362	METHODS
25363	METHODS
25364	METHODS
25365	METHODS
25366	METHODS
25367	METHODS
25368	RESULTS
25369	RESULTS
25370	RESULTS
25371	RESULTS
25372	RESULTS
25373	CONCLUSIONS
25374	BACKGROUND
25375	METHODS
25376	OBJECTIVE
25377	BACKGROUND
25378	OBJECTIVE
25379	METHODS
25380	METHODS
25381	METHODS
25382	METHODS
25383	METHODS
25384	METHODS
25385	RESULTS
25386	RESULTS
25387	RESULTS
25388	RESULTS
25389	RESULTS
25390	RESULTS
25391	CONCLUSIONS
25392	OBJECTIVE
25393	BACKGROUND
25394	BACKGROUND
25395	BACKGROUND
25396	OBJECTIVE
25397	METHODS
25398	METHODS
25399	METHODS
25400	RESULTS
25401	RESULTS
25402	RESULTS
25403	RESULTS
25404	RESULTS
25405	RESULTS
25406	CONCLUSIONS
25407	CONCLUSIONS
25408	OBJECTIVE
25409	METHODS
25410	METHODS
25411	METHODS
25412	RESULTS
25413	RESULTS
25414	RESULTS
25415	RESULTS
25416	RESULTS
25417	CONCLUSIONS
25418	BACKGROUND
25419	OBJECTIVE
25420	METHODS
25421	METHODS
25422	METHODS
25423	METHODS
25424	RESULTS
25425	RESULTS
25426	CONCLUSIONS
25427	RESULTS
25428	CONCLUSIONS
25429	OBJECTIVE
25430	METHODS
25431	METHODS
25432	RESULTS
25433	RESULTS
25434	CONCLUSIONS
25435	RESULTS
25436	CONCLUSIONS
25437	OBJECTIVE
25438	METHODS
25439	METHODS
25440	METHODS
25441	RESULTS
25442	RESULTS
25443	RESULTS
25444	RESULTS
25445	RESULTS
25446	RESULTS
25447	RESULTS
25448	RESULTS
25449	RESULTS
25450	CONCLUSIONS
25451	CONCLUSIONS
25452	OBJECTIVE
25453	METHODS
25454	METHODS
25455	METHODS
25456	METHODS
25457	METHODS
25458	METHODS
25459	RESULTS
25460	RESULTS
25461	RESULTS
25462	RESULTS
25463	CONCLUSIONS
25464	CONCLUSIONS
25465	OBJECTIVE
25466	METHODS
25467	METHODS
25468	METHODS
25469	METHODS
25470	RESULTS
25471	METHODS
25472	METHODS
25473	RESULTS
25474	RESULTS
25475	RESULTS
25476	RESULTS
25477	RESULTS
25478	RESULTS
25479	METHODS
25480	RESULTS
25481	RESULTS
25482	RESULTS
25483	CONCLUSIONS
25484	CONCLUSIONS
25485	CONCLUSIONS
25486	METHODS
25487	OBJECTIVE
25488	BACKGROUND
25489	METHODS
25490	METHODS
25491	METHODS
25492	RESULTS
25493	RESULTS
25494	RESULTS
25495	RESULTS
25496	RESULTS
25497	CONCLUSIONS
25498	CONCLUSIONS
25499	BACKGROUND
25500	BACKGROUND
25501	METHODS
25502	METHODS
25503	METHODS
25504	METHODS
25505	METHODS
25506	METHODS
25507	METHODS
25508	RESULTS
25509	RESULTS
25510	RESULTS
25511	CONCLUSIONS
25512	BACKGROUND
25513	OBJECTIVE
25514	METHODS
25515	METHODS
25516	RESULTS
25517	RESULTS
25518	RESULTS
25519	RESULTS
25520	RESULTS
25521	CONCLUSIONS
25522	OBJECTIVE
25523	METHODS
25524	METHODS
25525	METHODS
25526	METHODS
25527	METHODS
25528	METHODS
25529	METHODS
25530	RESULTS
25531	RESULTS
25532	OBJECTIVE
25533	METHODS
25534	METHODS
25535	METHODS
25536	METHODS
25537	METHODS
25538	METHODS
25539	RESULTS
25540	RESULTS
25541	CONCLUSIONS
25542	METHODS
25543	OBJECTIVE
25544	METHODS
25545	METHODS
25546	METHODS
25547	METHODS
25548	METHODS
25549	RESULTS
25550	RESULTS
25551	RESULTS
25552	RESULTS
25553	RESULTS
25554	RESULTS
25555	BACKGROUND
25556	CONCLUSIONS
25557	CONCLUSIONS
25558	BACKGROUND
25559	OBJECTIVE
25560	METHODS
25561	METHODS
25562	METHODS
25563	RESULTS
25564	RESULTS
25565	RESULTS
25566	RESULTS
25567	CONCLUSIONS
25568	CONCLUSIONS
25569	BACKGROUND
25570	BACKGROUND
25571	BACKGROUND
25572	METHODS
25573	METHODS
25574	RESULTS
25575	RESULTS
25576	RESULTS
25577	RESULTS
25578	RESULTS
25579	RESULTS
25580	RESULTS
25581	CONCLUSIONS
25582	CONCLUSIONS
25583	OBJECTIVE
25584	METHODS
25585	METHODS
25586	METHODS
25587	METHODS
25588	RESULTS
25589	RESULTS
25590	RESULTS
25591	CONCLUSIONS
25592	BACKGROUND
25593	BACKGROUND
25594	OBJECTIVE
25595	METHODS
25596	METHODS
25597	METHODS
25598	METHODS
25599	RESULTS
25600	RESULTS
25601	RESULTS
25602	CONCLUSIONS
25603	BACKGROUND
25604	OBJECTIVE
25605	OBJECTIVE
25606	METHODS
25607	METHODS
25608	METHODS
25609	METHODS
25610	METHODS
25611	RESULTS
25612	RESULTS
25613	CONCLUSIONS
25614	OBJECTIVE
25615	METHODS
25616	RESULTS
25617	RESULTS
25618	CONCLUSIONS
25619	OBJECTIVE
25620	METHODS
25621	METHODS
25622	METHODS
25623	METHODS
25624	METHODS
25625	METHODS
25626	RESULTS
25627	RESULTS
25628	RESULTS
25629	RESULTS
25630	CONCLUSIONS
25631	CONCLUSIONS
25632	BACKGROUND
25633	BACKGROUND
25634	BACKGROUND
25635	METHODS
25636	METHODS
25637	METHODS
25638	METHODS
25639	METHODS
25640	RESULTS
25641	RESULTS
25642	RESULTS
25643	RESULTS
25644	RESULTS
25645	RESULTS
25646	RESULTS
25647	RESULTS
25648	CONCLUSIONS
25649	RESULTS
25650	CONCLUSIONS
25651	BACKGROUND
25652	BACKGROUND
25653	METHODS
25654	METHODS
25655	METHODS
25656	RESULTS
25657	RESULTS
25658	RESULTS
25659	RESULTS
25660	CONCLUSIONS
25661	CONCLUSIONS
25662	CONCLUSIONS
25663	OBJECTIVE
25664	OBJECTIVE
25665	METHODS
25666	METHODS
25667	METHODS
25668	METHODS
25669	RESULTS
25670	RESULTS
25671	RESULTS
25672	RESULTS
25673	RESULTS
25674	CONCLUSIONS
25675	CONCLUSIONS
25676	BACKGROUND
25677	BACKGROUND
25678	BACKGROUND
25679	METHODS
25680	METHODS
25681	METHODS
25682	METHODS
25683	METHODS
25684	METHODS
25685	METHODS
25686	CONCLUSIONS
25687	CONCLUSIONS
25688	BACKGROUND
25689	OBJECTIVE
25690	METHODS
25691	METHODS
25692	METHODS
25693	OBJECTIVE
25694	RESULTS
25695	RESULTS
25696	RESULTS
25697	RESULTS
25698	RESULTS
25699	RESULTS
25700	RESULTS
25701	CONCLUSIONS
25702	BACKGROUND
25703	OBJECTIVE
25704	METHODS
25705	METHODS
25706	METHODS
25707	METHODS
25708	METHODS
25709	RESULTS
25710	RESULTS
25711	RESULTS
25712	RESULTS
25713	RESULTS
25714	RESULTS
25715	RESULTS
25716	RESULTS
25717	RESULTS
25718	CONCLUSIONS
25719	BACKGROUND
25720	BACKGROUND
25721	OBJECTIVE
25722	METHODS
25723	METHODS
25724	METHODS
25725	RESULTS
25726	RESULTS
25727	CONCLUSIONS
25728	CONCLUSIONS
25729	OBJECTIVE
25730	METHODS
25731	METHODS
25732	METHODS
25733	METHODS
25734	RESULTS
25735	RESULTS
25736	RESULTS
25737	RESULTS
25738	RESULTS
25739	RESULTS
25740	RESULTS
25741	CONCLUSIONS
25742	RESULTS
25743	CONCLUSIONS
25744	BACKGROUND
25745	BACKGROUND
25746	BACKGROUND
25747	BACKGROUND
25748	BACKGROUND
25749	METHODS
25750	METHODS
25751	RESULTS
25752	RESULTS
25753	RESULTS
25754	CONCLUSIONS
25755	OBJECTIVE
25756	METHODS
25757	METHODS
25758	RESULTS
25759	CONCLUSIONS
25760	CONCLUSIONS
25761	OBJECTIVE
25762	BACKGROUND
25763	OBJECTIVE
25764	METHODS
25765	METHODS
25766	RESULTS
25767	METHODS
25768	METHODS
25769	RESULTS
25770	RESULTS
25771	RESULTS
25772	CONCLUSIONS
25773	RESULTS
25774	RESULTS
25775	RESULTS
25776	RESULTS
25777	RESULTS
25778	CONCLUSIONS
25779	BACKGROUND
25780	OBJECTIVE
25781	METHODS
25782	METHODS
25783	METHODS
25784	METHODS
25785	METHODS
25786	METHODS
25787	METHODS
25788	METHODS
25789	RESULTS
25790	RESULTS
25791	RESULTS
25792	RESULTS
25793	RESULTS
25794	CONCLUSIONS
25795	BACKGROUND
25796	BACKGROUND
25797	OBJECTIVE
25798	METHODS
25799	METHODS
25800	METHODS
25801	RESULTS
25802	RESULTS
25803	RESULTS
25804	METHODS
25805	RESULTS
25806	CONCLUSIONS
25807	OBJECTIVE
25808	METHODS
25809	METHODS
25810	RESULTS
25811	CONCLUSIONS
25812	METHODS
25813	CONCLUSIONS
25814	RESULTS
25815	OBJECTIVE
25816	METHODS
25817	METHODS
25818	METHODS
25819	METHODS
25820	RESULTS
25821	RESULTS
25822	RESULTS
25823	CONCLUSIONS
25824	CONCLUSIONS
25825	BACKGROUND
25826	OBJECTIVE
25827	METHODS
25828	METHODS
25829	METHODS
25830	RESULTS
25831	RESULTS
25832	RESULTS
25833	RESULTS
25834	CONCLUSIONS
25835	OBJECTIVE
25836	METHODS
25837	METHODS
25838	METHODS
25839	METHODS
25840	METHODS
25841	METHODS
25842	METHODS
25843	RESULTS
25844	RESULTS
25845	RESULTS
25846	CONCLUSIONS
25847	CONCLUSIONS
25848	OBJECTIVE
25849	METHODS
25850	METHODS
25851	RESULTS
25852	RESULTS
25853	RESULTS
25854	RESULTS
25855	RESULTS
25856	RESULTS
25857	RESULTS
25858	RESULTS
25859	CONCLUSIONS
25860	RESULTS
25861	OBJECTIVE
25862	METHODS
25863	METHODS
25864	METHODS
25865	METHODS
25866	METHODS
25867	METHODS
25868	RESULTS
25869	RESULTS
25870	CONCLUSIONS
25871	OBJECTIVE
25872	METHODS
25873	METHODS
25874	METHODS
25875	RESULTS
25876	RESULTS
25877	RESULTS
25878	RESULTS
25879	RESULTS
25880	RESULTS
25881	RESULTS
25882	CONCLUSIONS
25883	BACKGROUND
25884	BACKGROUND
25885	BACKGROUND
25886	METHODS
25887	METHODS
25888	METHODS
25889	METHODS
25890	METHODS
25891	METHODS
25892	METHODS
25893	METHODS
25894	BACKGROUND
25895	CONCLUSIONS
25896	BACKGROUND
25897	OBJECTIVE
25898	METHODS
25899	METHODS
25900	METHODS
25901	METHODS
25902	METHODS
25903	RESULTS
25904	RESULTS
25905	RESULTS
25906	RESULTS
25907	RESULTS
25908	CONCLUSIONS
25909	BACKGROUND
25910	BACKGROUND
25911	METHODS
25912	METHODS
25913	METHODS
25914	METHODS
25915	RESULTS
25916	RESULTS
25917	RESULTS
25918	RESULTS
25919	CONCLUSIONS
25920	OBJECTIVE
25921	METHODS
25922	METHODS
25923	METHODS
25924	RESULTS
25925	RESULTS
25926	RESULTS
25927	METHODS
25928	RESULTS
25929	METHODS
25930	RESULTS
25931	RESULTS
25932	CONCLUSIONS
25933	RESULTS
25934	CONCLUSIONS
25935	OBJECTIVE
25936	METHODS
25937	METHODS
25938	METHODS
25939	METHODS
25940	METHODS
25941	RESULTS
25942	RESULTS
25943	RESULTS
25944	CONCLUSIONS
25945	CONCLUSIONS
25946	CONCLUSIONS
25947	OBJECTIVE
25948	METHODS
25949	METHODS
25950	METHODS
25951	RESULTS
25952	RESULTS
25953	RESULTS
25954	RESULTS
25955	RESULTS
25956	RESULTS
25957	RESULTS
25958	RESULTS
25959	CONCLUSIONS
25960	OBJECTIVE
25961	METHODS
25962	METHODS
25963	METHODS
25964	METHODS
25965	RESULTS
25966	RESULTS
25967	RESULTS
25968	RESULTS
25969	RESULTS
25970	CONCLUSIONS
25971	CONCLUSIONS
25972	OBJECTIVE
25973	METHODS
25974	RESULTS
25975	RESULTS
25976	RESULTS
25977	RESULTS
25978	CONCLUSIONS
25979	CONCLUSIONS
25980	OBJECTIVE
25981	METHODS
25982	METHODS
25983	METHODS
25984	METHODS
25985	METHODS
25986	RESULTS
25987	RESULTS
25988	CONCLUSIONS
25989	OBJECTIVE
25990	METHODS
25991	METHODS
25992	METHODS
25993	METHODS
25994	RESULTS
25995	RESULTS
25996	RESULTS
25997	RESULTS
25998	CONCLUSIONS
25999	BACKGROUND
26000	BACKGROUND
26001	BACKGROUND
26002	METHODS
26003	METHODS
26004	RESULTS
26005	RESULTS
26006	RESULTS
26007	RESULTS
26008	RESULTS
26009	CONCLUSIONS
26010	RESULTS
26011	OBJECTIVE
26012	CONCLUSIONS
26013	CONCLUSIONS
26014	CONCLUSIONS
26015	METHODS
26016	METHODS
26017	RESULTS
26018	METHODS
26019	METHODS
26020	METHODS
26021	METHODS
26022	RESULTS
26023	RESULTS
26024	RESULTS
26025	RESULTS
26026	RESULTS
26027	RESULTS
26028	RESULTS
26029	RESULTS
26030	RESULTS
26031	RESULTS
26032	RESULTS
26033	CONCLUSIONS
26034	RESULTS
26035	CONCLUSIONS
26036	CONCLUSIONS
26037	RESULTS
26038	CONCLUSIONS
26039	CONCLUSIONS
26040	BACKGROUND
26041	BACKGROUND
26042	METHODS
26043	OBJECTIVE
26044	METHODS
26045	METHODS
26046	METHODS
26047	CONCLUSIONS
26048	METHODS
26049	METHODS
26050	METHODS
26051	CONCLUSIONS
26052	BACKGROUND
26053	BACKGROUND
26054	OBJECTIVE
26055	BACKGROUND
26056	METHODS
26057	METHODS
26058	METHODS
26059	RESULTS
26060	RESULTS
26061	RESULTS
26062	CONCLUSIONS
26063	OBJECTIVE
26064	METHODS
26065	METHODS
26066	METHODS
26067	RESULTS
26068	RESULTS
26069	RESULTS
26070	CONCLUSIONS
26071	CONCLUSIONS
26072	CONCLUSIONS
26073	OBJECTIVE
26074	METHODS
26075	METHODS
26076	METHODS
26077	METHODS
26078	METHODS
26079	RESULTS
26080	RESULTS
26081	CONCLUSIONS
26082	BACKGROUND
26083	OBJECTIVE
26084	METHODS
26085	METHODS
26086	METHODS
26087	METHODS
26088	METHODS
26089	RESULTS
26090	RESULTS
26091	RESULTS
26092	RESULTS
26093	CONCLUSIONS
26094	BACKGROUND
26095	BACKGROUND
26096	METHODS
26097	METHODS
26098	RESULTS
26099	RESULTS
26100	RESULTS
26101	RESULTS
26102	CONCLUSIONS
26103	BACKGROUND
26104	BACKGROUND
26105	OBJECTIVE
26106	METHODS
26107	METHODS
26108	METHODS
26109	RESULTS
26110	RESULTS
26111	RESULTS
26112	RESULTS
26113	CONCLUSIONS
26114	OBJECTIVE
26115	METHODS
26116	METHODS
26117	METHODS
26118	METHODS
26119	RESULTS
26120	RESULTS
26121	RESULTS
26122	RESULTS
26123	RESULTS
26124	CONCLUSIONS
26125	BACKGROUND
26126	BACKGROUND
26127	BACKGROUND
26128	METHODS
26129	METHODS
26130	METHODS
26131	RESULTS
26132	METHODS
26133	RESULTS
26134	RESULTS
26135	RESULTS
26136	BACKGROUND
26137	CONCLUSIONS
26138	CONCLUSIONS
26139	BACKGROUND
26140	BACKGROUND
26141	BACKGROUND
26142	OBJECTIVE
26143	METHODS
26144	METHODS
26145	METHODS
26146	METHODS
26147	METHODS
26148	RESULTS
26149	RESULTS
26150	RESULTS
26151	CONCLUSIONS
26152	CONCLUSIONS
26153	CONCLUSIONS
26154	BACKGROUND
26155	METHODS
26156	METHODS
26157	RESULTS
26158	RESULTS
26159	RESULTS
26160	RESULTS
26161	RESULTS
26162	RESULTS
26163	RESULTS
26164	CONCLUSIONS
26165	OBJECTIVE
26166	METHODS
26167	METHODS
26168	METHODS
26169	METHODS
26170	RESULTS
26171	RESULTS
26172	RESULTS
26173	RESULTS
26174	CONCLUSIONS
26175	RESULTS
26176	BACKGROUND
26177	CONCLUSIONS
26178	BACKGROUND
26179	OBJECTIVE
26180	METHODS
26181	METHODS
26182	METHODS
26183	METHODS
26184	METHODS
26185	METHODS
26186	METHODS
26187	RESULTS
26188	RESULTS
26189	RESULTS
26190	RESULTS
26191	RESULTS
26192	CONCLUSIONS
26193	OBJECTIVE
26194	METHODS
26195	METHODS
26196	METHODS
26197	METHODS
26198	METHODS
26199	RESULTS
26200	RESULTS
26201	RESULTS
26202	RESULTS
26203	CONCLUSIONS
26204	CONCLUSIONS
26205	OBJECTIVE
26206	OBJECTIVE
26207	METHODS
26208	METHODS
26209	METHODS
26210	METHODS
26211	RESULTS
26212	RESULTS
26213	RESULTS
26214	RESULTS
26215	RESULTS
26216	RESULTS
26217	CONCLUSIONS
26218	BACKGROUND
26219	BACKGROUND
26220	OBJECTIVE
26221	METHODS
26222	METHODS
26223	RESULTS
26224	RESULTS
26225	CONCLUSIONS
26226	OBJECTIVE
26227	METHODS
26228	METHODS
26229	METHODS
26230	RESULTS
26231	RESULTS
26232	RESULTS
26233	RESULTS
26234	RESULTS
26235	RESULTS
26236	OBJECTIVE
26237	BACKGROUND
26238	METHODS
26239	METHODS
26240	OBJECTIVE
26241	METHODS
26242	METHODS
26243	METHODS
26244	RESULTS
26245	RESULTS
26246	RESULTS
26247	CONCLUSIONS
26248	BACKGROUND
26249	OBJECTIVE
26250	METHODS
26251	METHODS
26252	METHODS
26253	METHODS
26254	RESULTS
26255	RESULTS
26256	RESULTS
26257	CONCLUSIONS
26258	BACKGROUND
26259	BACKGROUND
26260	METHODS
26261	RESULTS
26262	RESULTS
26263	METHODS
26264	RESULTS
26265	CONCLUSIONS
26266	CONCLUSIONS
26267	OBJECTIVE
26268	METHODS
26269	METHODS
26270	METHODS
26271	METHODS
26272	METHODS
26273	RESULTS
26274	RESULTS
26275	RESULTS
26276	RESULTS
26277	RESULTS
26278	RESULTS
26279	CONCLUSIONS
26280	CONCLUSIONS
26281	OBJECTIVE
26282	METHODS
26283	METHODS
26284	RESULTS
26285	RESULTS
26286	RESULTS
26287	CONCLUSIONS
26288	OBJECTIVE
26289	METHODS
26290	METHODS
26291	METHODS
26292	METHODS
26293	RESULTS
26294	RESULTS
26295	RESULTS
26296	RESULTS
26297	RESULTS
26298	CONCLUSIONS
26299	CONCLUSIONS
26300	CONCLUSIONS
26301	CONCLUSIONS
26302	OBJECTIVE
26303	METHODS
26304	METHODS
26305	METHODS
26306	RESULTS
26307	RESULTS
26308	RESULTS
26309	RESULTS
26310	CONCLUSIONS
26311	OBJECTIVE
26312	BACKGROUND
26313	METHODS
26314	METHODS
26315	METHODS
26316	RESULTS
26317	RESULTS
26318	RESULTS
26319	RESULTS
26320	CONCLUSIONS
26321	BACKGROUND
26322	BACKGROUND
26323	METHODS
26324	METHODS
26325	RESULTS
26326	RESULTS
26327	RESULTS
26328	RESULTS
26329	CONCLUSIONS
26330	CONCLUSIONS
26331	OBJECTIVE
26332	METHODS
26333	METHODS
26334	METHODS
26335	METHODS
26336	METHODS
26337	RESULTS
26338	RESULTS
26339	RESULTS
26340	RESULTS
26341	CONCLUSIONS
26342	OBJECTIVE
26343	METHODS
26344	METHODS
26345	METHODS
26346	METHODS
26347	METHODS
26348	METHODS
26349	RESULTS
26350	RESULTS
26351	RESULTS
26352	RESULTS
26353	RESULTS
26354	CONCLUSIONS
26355	RESULTS
26356	CONCLUSIONS
26357	BACKGROUND
26358	METHODS
26359	BACKGROUND
26360	OBJECTIVE
26361	METHODS
26362	METHODS
26363	METHODS
26364	RESULTS
26365	METHODS
26366	METHODS
26367	RESULTS
26368	RESULTS
26369	RESULTS
26370	RESULTS
26371	RESULTS
26372	RESULTS
26373	RESULTS
26374	RESULTS
26375	CONCLUSIONS
26376	OBJECTIVE
26377	METHODS
26378	METHODS
26379	METHODS
26380	METHODS
26381	RESULTS
26382	METHODS
26383	METHODS
26384	METHODS
26385	RESULTS
26386	RESULTS
26387	RESULTS
26388	RESULTS
26389	RESULTS
26390	RESULTS
26391	RESULTS
26392	CONCLUSIONS
26393	BACKGROUND
26394	OBJECTIVE
26395	METHODS
26396	METHODS
26397	METHODS
26398	RESULTS
26399	RESULTS
26400	RESULTS
26401	RESULTS
26402	RESULTS
26403	RESULTS
26404	BACKGROUND
26405	OBJECTIVE
26406	METHODS
26407	METHODS
26408	RESULTS
26409	RESULTS
26410	RESULTS
26411	RESULTS
26412	RESULTS
26413	RESULTS
26414	CONCLUSIONS
26415	BACKGROUND
26416	OBJECTIVE
26417	BACKGROUND
26418	METHODS
26419	METHODS
26420	METHODS
26421	RESULTS
26422	RESULTS
26423	RESULTS
26424	RESULTS
26425	CONCLUSIONS
26426	RESULTS
26427	RESULTS
26428	OBJECTIVE
26429	BACKGROUND
26430	METHODS
26431	METHODS
26432	RESULTS
26433	RESULTS
26434	RESULTS
26435	RESULTS
26436	CONCLUSIONS
26437	CONCLUSIONS
26438	BACKGROUND
26439	BACKGROUND
26440	OBJECTIVE
26441	METHODS
26442	METHODS
26443	METHODS
26444	METHODS
26445	RESULTS
26446	METHODS
26447	METHODS
26448	METHODS
26449	METHODS
26450	METHODS
26451	RESULTS
26452	RESULTS
26453	METHODS
26454	RESULTS
26455	RESULTS
26456	METHODS
26457	RESULTS
26458	CONCLUSIONS
26459	RESULTS
26460	OBJECTIVE
26461	METHODS
26462	METHODS
26463	METHODS
26464	RESULTS
26465	RESULTS
26466	RESULTS
26467	CONCLUSIONS
26468	CONCLUSIONS
26469	CONCLUSIONS
26470	BACKGROUND
26471	BACKGROUND
26472	OBJECTIVE
26473	METHODS
26474	METHODS
26475	RESULTS
26476	RESULTS
26477	RESULTS
26478	CONCLUSIONS
26479	CONCLUSIONS
26480	OBJECTIVE
26481	METHODS
26482	METHODS
26483	METHODS
26484	METHODS
26485	METHODS
26486	RESULTS
26487	RESULTS
26488	CONCLUSIONS
26489	BACKGROUND
26490	BACKGROUND
26491	OBJECTIVE
26492	METHODS
26493	METHODS
26494	METHODS
26495	METHODS
26496	METHODS
26497	METHODS
26498	METHODS
26499	METHODS
26500	RESULTS
26501	RESULTS
26502	RESULTS
26503	RESULTS
26504	RESULTS
26505	CONCLUSIONS
26506	CONCLUSIONS
26507	CONCLUSIONS
26508	CONCLUSIONS
26509	CONCLUSIONS
26510	RESULTS
26511	CONCLUSIONS
26512	BACKGROUND
26513	OBJECTIVE
26514	METHODS
26515	METHODS
26516	METHODS
26517	RESULTS
26518	RESULTS
26519	RESULTS
26520	RESULTS
26521	CONCLUSIONS
26522	BACKGROUND
26523	BACKGROUND
26524	BACKGROUND
26525	METHODS
26526	METHODS
26527	METHODS
26528	RESULTS
26529	RESULTS
26530	RESULTS
26531	RESULTS
26532	RESULTS
26533	RESULTS
26534	RESULTS
26535	RESULTS
26536	CONCLUSIONS
26537	CONCLUSIONS
26538	CONCLUSIONS
26539	BACKGROUND
26540	BACKGROUND
26541	BACKGROUND
26542	OBJECTIVE
26543	METHODS
26544	RESULTS
26545	METHODS
26546	METHODS
26547	RESULTS
26548	RESULTS
26549	RESULTS
26550	RESULTS
26551	CONCLUSIONS
26552	BACKGROUND
26553	BACKGROUND
26554	METHODS
26555	METHODS
26556	METHODS
26557	METHODS
26558	RESULTS
26559	RESULTS
26560	RESULTS
26561	CONCLUSIONS
26562	CONCLUSIONS
26563	CONCLUSIONS
26564	OBJECTIVE
26565	METHODS
26566	METHODS
26567	METHODS
26568	METHODS
26569	RESULTS
26570	RESULTS
26571	RESULTS
26572	RESULTS
26573	CONCLUSIONS
26574	BACKGROUND
26575	CONCLUSIONS
26576	OBJECTIVE
26577	METHODS
26578	METHODS
26579	METHODS
26580	METHODS
26581	METHODS
26582	METHODS
26583	RESULTS
26584	RESULTS
26585	RESULTS
26586	RESULTS
26587	RESULTS
26588	CONCLUSIONS
26589	BACKGROUND
26590	BACKGROUND
26591	METHODS
26592	METHODS
26593	RESULTS
26594	RESULTS
26595	RESULTS
26596	RESULTS
26597	RESULTS
26598	RESULTS
26599	CONCLUSIONS
26600	CONCLUSIONS
26601	BACKGROUND
26602	BACKGROUND
26603	RESULTS
26604	BACKGROUND
26605	METHODS
26606	RESULTS
26607	RESULTS
26608	RESULTS
26609	RESULTS
26610	RESULTS
26611	RESULTS
26612	RESULTS
26613	BACKGROUND
26614	OBJECTIVE
26615	METHODS
26616	METHODS
26617	METHODS
26618	RESULTS
26619	RESULTS
26620	RESULTS
26621	RESULTS
26622	RESULTS
26623	CONCLUSIONS
26624	CONCLUSIONS
26625	BACKGROUND
26626	OBJECTIVE
26627	METHODS
26628	METHODS
26629	METHODS
26630	RESULTS
26631	RESULTS
26632	RESULTS
26633	RESULTS
26634	RESULTS
26635	RESULTS
26636	CONCLUSIONS
26637	CONCLUSIONS
26638	CONCLUSIONS
26639	BACKGROUND
26640	METHODS
26641	METHODS
26642	RESULTS
26643	RESULTS
26644	RESULTS
26645	CONCLUSIONS
26646	CONCLUSIONS
26647	OBJECTIVE
26648	METHODS
26649	METHODS
26650	METHODS
26651	METHODS
26652	METHODS
26653	RESULTS
26654	RESULTS
26655	RESULTS
26656	RESULTS
26657	RESULTS
26658	RESULTS
26659	RESULTS
26660	CONCLUSIONS
26661	CONCLUSIONS
26662	OBJECTIVE
26663	METHODS
26664	METHODS
26665	METHODS
26666	RESULTS
26667	RESULTS
26668	CONCLUSIONS
26669	BACKGROUND
26670	BACKGROUND
26671	OBJECTIVE
26672	METHODS
26673	METHODS
26674	METHODS
26675	METHODS
26676	METHODS
26677	RESULTS
26678	RESULTS
26679	RESULTS
26680	RESULTS
26681	RESULTS
26682	CONCLUSIONS
26683	OBJECTIVE
26684	METHODS
26685	METHODS
26686	METHODS
26687	RESULTS
26688	RESULTS
26689	RESULTS
26690	RESULTS
26691	CONCLUSIONS
26692	OBJECTIVE
26693	METHODS
26694	METHODS
26695	METHODS
26696	RESULTS
26697	METHODS
26698	METHODS
26699	METHODS
26700	METHODS
26701	RESULTS
26702	RESULTS
26703	RESULTS
26704	CONCLUSIONS
26705	BACKGROUND
26706	BACKGROUND
26707	BACKGROUND
26708	BACKGROUND
26709	BACKGROUND
26710	OBJECTIVE
26711	METHODS
26712	METHODS
26713	RESULTS
26714	RESULTS
26715	RESULTS
26716	RESULTS
26717	CONCLUSIONS
26718	CONCLUSIONS
26719	BACKGROUND
26720	BACKGROUND
26721	METHODS
26722	METHODS
26723	RESULTS
26724	RESULTS
26725	RESULTS
26726	BACKGROUND
26727	RESULTS
26728	CONCLUSIONS
26729	CONCLUSIONS
26730	OBJECTIVE
26731	METHODS
26732	METHODS
26733	METHODS
26734	METHODS
26735	METHODS
26736	METHODS
26737	RESULTS
26738	RESULTS
26739	RESULTS
26740	RESULTS
26741	CONCLUSIONS
26742	CONCLUSIONS
26743	BACKGROUND
26744	OBJECTIVE
26745	METHODS
26746	METHODS
26747	METHODS
26748	METHODS
26749	RESULTS
26750	RESULTS
26751	RESULTS
26752	CONCLUSIONS
26753	CONCLUSIONS
26754	CONCLUSIONS
26755	OBJECTIVE
26756	METHODS
26757	METHODS
26758	METHODS
26759	METHODS
26760	METHODS
26761	RESULTS
26762	CONCLUSIONS
26763	BACKGROUND
26764	BACKGROUND
26765	OBJECTIVE
26766	METHODS
26767	METHODS
26768	METHODS
26769	METHODS
26770	RESULTS
26771	RESULTS
26772	RESULTS
26773	CONCLUSIONS
26774	BACKGROUND
26775	BACKGROUND
26776	BACKGROUND
26777	METHODS
26778	METHODS
26779	METHODS
26780	RESULTS
26781	RESULTS
26782	RESULTS
26783	CONCLUSIONS
26784	BACKGROUND
26785	BACKGROUND
26786	OBJECTIVE
26787	METHODS
26788	METHODS
26789	METHODS
26790	RESULTS
26791	METHODS
26792	METHODS
26793	RESULTS
26794	CONCLUSIONS
26795	OBJECTIVE
26796	METHODS
26797	METHODS
26798	RESULTS
26799	RESULTS
26800	RESULTS
26801	RESULTS
26802	RESULTS
26803	CONCLUSIONS
26804	CONCLUSIONS
26805	RESULTS
26806	OBJECTIVE
26807	METHODS
26808	METHODS
26809	RESULTS
26810	RESULTS
26811	RESULTS
26812	RESULTS
26813	RESULTS
26814	RESULTS
26815	RESULTS
26816	CONCLUSIONS
26817	CONCLUSIONS
26818	BACKGROUND
26819	OBJECTIVE
26820	METHODS
26821	METHODS
26822	METHODS
26823	RESULTS
26824	RESULTS
26825	CONCLUSIONS
26826	METHODS
26827	OBJECTIVE
26828	METHODS
26829	METHODS
26830	METHODS
26831	METHODS
26832	METHODS
26833	METHODS
26834	METHODS
26835	RESULTS
26836	RESULTS
26837	RESULTS
26838	CONCLUSIONS
26839	BACKGROUND
26840	CONCLUSIONS
26841	BACKGROUND
26842	BACKGROUND
26843	OBJECTIVE
26844	METHODS
26845	METHODS
26846	METHODS
26847	RESULTS
26848	RESULTS
26849	CONCLUSIONS
26850	CONCLUSIONS
26851	OBJECTIVE
26852	METHODS
26853	METHODS
26854	METHODS
26855	RESULTS
26856	METHODS
26857	METHODS
26858	METHODS
26859	RESULTS
26860	RESULTS
26861	CONCLUSIONS
26862	CONCLUSIONS
26863	OBJECTIVE
26864	BACKGROUND
26865	METHODS
26866	RESULTS
26867	RESULTS
26868	RESULTS
26869	CONCLUSIONS
26870	OBJECTIVE
26871	METHODS
26872	METHODS
26873	RESULTS
26874	RESULTS
26875	RESULTS
26876	RESULTS
26877	RESULTS
26878	CONCLUSIONS
26879	RESULTS
26880	BACKGROUND
26881	OBJECTIVE
26882	METHODS
26883	METHODS
26884	RESULTS
26885	RESULTS
26886	CONCLUSIONS
26887	OBJECTIVE
26888	BACKGROUND
26889	CONCLUSIONS
26890	OBJECTIVE
26891	RESULTS
26892	METHODS
26893	RESULTS
26894	RESULTS
26895	RESULTS
26896	RESULTS
26897	RESULTS
26898	CONCLUSIONS
26899	BACKGROUND
26900	BACKGROUND
26901	BACKGROUND
26902	METHODS
26903	METHODS
26904	METHODS
26905	OBJECTIVE
26906	METHODS
26907	METHODS
26908	METHODS
26909	RESULTS
26910	RESULTS
26911	RESULTS
26912	RESULTS
26913	RESULTS
26914	RESULTS
26915	CONCLUSIONS
26916	CONCLUSIONS
26917	BACKGROUND
26918	BACKGROUND
26919	BACKGROUND
26920	BACKGROUND
26921	BACKGROUND
26922	OBJECTIVE
26923	METHODS
26924	METHODS
26925	METHODS
26926	METHODS
26927	METHODS
26928	RESULTS
26929	RESULTS
26930	RESULTS
26931	RESULTS
26932	RESULTS
26933	RESULTS
26934	CONCLUSIONS
26935	OBJECTIVE
26936	METHODS
26937	METHODS
26938	METHODS
26939	METHODS
26940	METHODS
26941	METHODS
26942	RESULTS
26943	RESULTS
26944	RESULTS
26945	CONCLUSIONS
26946	CONCLUSIONS
26947	CONCLUSIONS
26948	BACKGROUND
26949	BACKGROUND
26950	OBJECTIVE
26951	METHODS
26952	METHODS
26953	METHODS
26954	METHODS
26955	RESULTS
26956	RESULTS
26957	RESULTS
26958	RESULTS
26959	RESULTS
26960	CONCLUSIONS
26961	BACKGROUND
26962	CONCLUSIONS
26963	BACKGROUND
26964	METHODS
26965	METHODS
26966	METHODS
26967	RESULTS
26968	RESULTS
26969	RESULTS
26970	RESULTS
26971	RESULTS
26972	CONCLUSIONS
26973	CONCLUSIONS
26974	OBJECTIVE
26975	METHODS
26976	METHODS
26977	RESULTS
26978	RESULTS
26979	CONCLUSIONS
26980	BACKGROUND
26981	BACKGROUND
26982	METHODS
26983	METHODS
26984	METHODS
26985	METHODS
26986	METHODS
26987	RESULTS
26988	RESULTS
26989	RESULTS
26990	RESULTS
26991	RESULTS
26992	RESULTS
26993	RESULTS
26994	CONCLUSIONS
26995	BACKGROUND
26996	BACKGROUND
26997	BACKGROUND
26998	BACKGROUND
26999	BACKGROUND
27000	METHODS
27001	METHODS
27002	METHODS
27003	METHODS
27004	METHODS
27005	METHODS
27006	RESULTS
27007	RESULTS
27008	RESULTS
27009	CONCLUSIONS
27010	RESULTS
27011	RESULTS
27012	BACKGROUND
27013	METHODS
27014	METHODS
27015	METHODS
27016	METHODS
27017	METHODS
27018	METHODS
27019	RESULTS
27020	RESULTS
27021	RESULTS
27022	RESULTS
27023	RESULTS
27024	CONCLUSIONS
27025	CONCLUSIONS
27026	OBJECTIVE
27027	METHODS
27028	METHODS
27029	METHODS
27030	RESULTS
27031	RESULTS
27032	RESULTS
27033	RESULTS
27034	CONCLUSIONS
27035	BACKGROUND
27036	METHODS
27037	BACKGROUND
27038	METHODS
27039	METHODS
27040	RESULTS
27041	RESULTS
27042	RESULTS
27043	CONCLUSIONS
27044	CONCLUSIONS
27045	OBJECTIVE
27046	METHODS
27047	METHODS
27048	METHODS
27049	RESULTS
27050	RESULTS
27051	RESULTS
27052	RESULTS
27053	RESULTS
27054	RESULTS
27055	CONCLUSIONS
27056	CONCLUSIONS
27057	CONCLUSIONS
27058	CONCLUSIONS
27059	BACKGROUND
27060	METHODS
27061	RESULTS
27062	METHODS
27063	METHODS
27064	RESULTS
27065	RESULTS
27066	RESULTS
27067	RESULTS
27068	CONCLUSIONS
27069	CONCLUSIONS
27070	CONCLUSIONS
27071	BACKGROUND
27072	BACKGROUND
27073	METHODS
27074	METHODS
27075	METHODS
27076	METHODS
27077	METHODS
27078	METHODS
27079	RESULTS
27080	RESULTS
27081	RESULTS
27082	RESULTS
27083	CONCLUSIONS
27084	OBJECTIVE
27085	METHODS
27086	METHODS
27087	METHODS
27088	METHODS
27089	RESULTS
27090	RESULTS
27091	RESULTS
27092	CONCLUSIONS
27093	CONCLUSIONS
27094	OBJECTIVE
27095	METHODS
27096	METHODS
27097	RESULTS
27098	RESULTS
27099	RESULTS
27100	RESULTS
27101	CONCLUSIONS
27102	METHODS
27103	CONCLUSIONS
27104	BACKGROUND
27105	OBJECTIVE
27106	METHODS
27107	METHODS
27108	METHODS
27109	METHODS
27110	RESULTS
27111	RESULTS
27112	CONCLUSIONS
27113	CONCLUSIONS
27114	OBJECTIVE
27115	METHODS
27116	METHODS
27117	METHODS
27118	METHODS
27119	METHODS
27120	RESULTS
27121	RESULTS
27122	CONCLUSIONS
27123	CONCLUSIONS
27124	BACKGROUND
27125	CONCLUSIONS
27126	OBJECTIVE
27127	METHODS
27128	METHODS
27129	RESULTS
27130	METHODS
27131	METHODS
27132	RESULTS
27133	RESULTS
27134	RESULTS
27135	RESULTS
27136	RESULTS
27137	CONCLUSIONS
27138	OBJECTIVE
27139	OBJECTIVE
27140	BACKGROUND
27141	BACKGROUND
27142	CONCLUSIONS
27143	OBJECTIVE
27144	METHODS
27145	METHODS
27146	METHODS
27147	METHODS
27148	METHODS
27149	METHODS
27150	RESULTS
27151	RESULTS
27152	RESULTS
27153	RESULTS
27154	RESULTS
27155	CONCLUSIONS
27156	CONCLUSIONS
27157	CONCLUSIONS
27158	BACKGROUND
27159	BACKGROUND
27160	OBJECTIVE
27161	METHODS
27162	METHODS
27163	METHODS
27164	METHODS
27165	METHODS
27166	METHODS
27167	METHODS
27168	RESULTS
27169	RESULTS
27170	RESULTS
27171	RESULTS
27172	CONCLUSIONS
27173	OBJECTIVE
27174	METHODS
27175	METHODS
27176	RESULTS
27177	RESULTS
27178	RESULTS
27179	RESULTS
27180	RESULTS
27181	RESULTS
27182	RESULTS
27183	RESULTS
27184	OBJECTIVE
27185	METHODS
27186	METHODS
27187	RESULTS
27188	RESULTS
27189	RESULTS
27190	RESULTS
27191	CONCLUSIONS
27192	OBJECTIVE
27193	BACKGROUND
27194	METHODS
27195	METHODS
27196	METHODS
27197	METHODS
27198	METHODS
27199	METHODS
27200	METHODS
27201	RESULTS
27202	RESULTS
27203	RESULTS
27204	RESULTS
27205	RESULTS
27206	CONCLUSIONS
27207	CONCLUSIONS
27208	CONCLUSIONS
27209	BACKGROUND
27210	METHODS
27211	METHODS
27212	METHODS
27213	RESULTS
27214	RESULTS
27215	RESULTS
27216	RESULTS
27217	RESULTS
27218	CONCLUSIONS
27219	BACKGROUND
27220	BACKGROUND
27221	RESULTS
27222	RESULTS
27223	RESULTS
27224	RESULTS
27225	RESULTS
27226	RESULTS
27227	RESULTS
27228	RESULTS
27229	CONCLUSIONS
27230	CONCLUSIONS
27231	CONCLUSIONS
27232	BACKGROUND
27233	BACKGROUND
27234	METHODS
27235	METHODS
27236	METHODS
27237	METHODS
27238	METHODS
27239	METHODS
27240	RESULTS
27241	RESULTS
27242	RESULTS
27243	CONCLUSIONS
27244	CONCLUSIONS
27245	BACKGROUND
27246	BACKGROUND
27247	METHODS
27248	RESULTS
27249	RESULTS
27250	RESULTS
27251	RESULTS
27252	RESULTS
27253	CONCLUSIONS
27254	OBJECTIVE
27255	METHODS
27256	METHODS
27257	METHODS
27258	RESULTS
27259	RESULTS
27260	RESULTS
27261	CONCLUSIONS
27262	CONCLUSIONS
27263	CONCLUSIONS
27264	BACKGROUND
27265	METHODS
27266	METHODS
27267	METHODS
27268	RESULTS
27269	RESULTS
27270	RESULTS
27271	RESULTS
27272	RESULTS
27273	RESULTS
27274	RESULTS
27275	BACKGROUND
27276	CONCLUSIONS
27277	BACKGROUND
27278	BACKGROUND
27279	METHODS
27280	METHODS
27281	METHODS
27282	METHODS
27283	METHODS
27284	RESULTS
27285	RESULTS
27286	RESULTS
27287	RESULTS
27288	RESULTS
27289	CONCLUSIONS
27290	METHODS
27291	OBJECTIVE
27292	METHODS
27293	METHODS
27294	METHODS
27295	RESULTS
27296	RESULTS
27297	RESULTS
27298	RESULTS
27299	RESULTS
27300	CONCLUSIONS
27301	OBJECTIVE
27302	METHODS
27303	METHODS
27304	METHODS
27305	METHODS
27306	RESULTS
27307	RESULTS
27308	RESULTS
27309	RESULTS
27310	RESULTS
27311	CONCLUSIONS
27312	CONCLUSIONS
27313	OBJECTIVE
27314	METHODS
27315	METHODS
27316	METHODS
27317	RESULTS
27318	RESULTS
27319	RESULTS
27320	RESULTS
27321	CONCLUSIONS
27322	CONCLUSIONS
27323	OBJECTIVE
27324	METHODS
27325	METHODS
27326	METHODS
27327	RESULTS
27328	METHODS
27329	METHODS
27330	METHODS
27331	METHODS
27332	RESULTS
27333	RESULTS
27334	RESULTS
27335	RESULTS
27336	CONCLUSIONS
27337	CONCLUSIONS
27338	OBJECTIVE
27339	OBJECTIVE
27340	METHODS
27341	RESULTS
27342	METHODS
27343	RESULTS
27344	RESULTS
27345	RESULTS
27346	RESULTS
27347	CONCLUSIONS
27348	CONCLUSIONS
27349	CONCLUSIONS
27350	BACKGROUND
27351	BACKGROUND
27352	METHODS
27353	METHODS
27354	METHODS
27355	RESULTS
27356	CONCLUSIONS
27357	BACKGROUND
27358	BACKGROUND
27359	METHODS
27360	METHODS
27361	METHODS
27362	METHODS
27363	METHODS
27364	METHODS
27365	RESULTS
27366	RESULTS
27367	RESULTS
27368	RESULTS
27369	CONCLUSIONS
27370	BACKGROUND
27371	OBJECTIVE
27372	METHODS
27373	METHODS
27374	METHODS
27375	RESULTS
27376	RESULTS
27377	RESULTS
27378	RESULTS
27379	RESULTS
27380	CONCLUSIONS
27381	OBJECTIVE
27382	METHODS
27383	METHODS
27384	METHODS
27385	METHODS
27386	METHODS
27387	METHODS
27388	RESULTS
27389	METHODS
27390	RESULTS
27391	RESULTS
27392	CONCLUSIONS
27393	CONCLUSIONS
27394	BACKGROUND
27395	OBJECTIVE
27396	METHODS
27397	METHODS
27398	METHODS
27399	METHODS
27400	METHODS
27401	RESULTS
27402	RESULTS
27403	RESULTS
27404	RESULTS
27405	BACKGROUND
27406	CONCLUSIONS
27407	BACKGROUND
27408	OBJECTIVE
27409	METHODS
27410	METHODS
27411	METHODS
27412	RESULTS
27413	RESULTS
27414	CONCLUSIONS
27415	OBJECTIVE
27416	METHODS
27417	METHODS
27418	METHODS
27419	METHODS
27420	METHODS
27421	RESULTS
27422	RESULTS
27423	RESULTS
27424	RESULTS
27425	RESULTS
27426	CONCLUSIONS
27427	BACKGROUND
27428	CONCLUSIONS
27429	BACKGROUND
27430	BACKGROUND
27431	BACKGROUND
27432	BACKGROUND
27433	BACKGROUND
27434	BACKGROUND
27435	METHODS
27436	METHODS
27437	OBJECTIVE
27438	METHODS
27439	METHODS
27440	METHODS
27441	METHODS
27442	RESULTS
27443	CONCLUSIONS
27444	METHODS
27445	CONCLUSIONS
27446	CONCLUSIONS
27447	CONCLUSIONS
27448	BACKGROUND
27449	BACKGROUND
27450	BACKGROUND
27451	METHODS
27452	RESULTS
27453	RESULTS
27454	CONCLUSIONS
27455	BACKGROUND
27456	BACKGROUND
27457	BACKGROUND
27458	BACKGROUND
27459	METHODS
27460	CONCLUSIONS
27461	METHODS
27462	METHODS
27463	METHODS
27464	METHODS
27465	BACKGROUND
27466	BACKGROUND
27467	BACKGROUND
27468	OBJECTIVE
27469	METHODS
27470	METHODS
27471	METHODS
27472	METHODS
27473	METHODS
27474	RESULTS
27475	RESULTS
27476	RESULTS
27477	RESULTS
27478	RESULTS
27479	RESULTS
27480	CONCLUSIONS
27481	CONCLUSIONS
27482	CONCLUSIONS
27483	BACKGROUND
27484	BACKGROUND
27485	BACKGROUND
27486	METHODS
27487	METHODS
27488	METHODS
27489	METHODS
27490	RESULTS
27491	RESULTS
27492	RESULTS
27493	RESULTS
27494	CONCLUSIONS
27495	CONCLUSIONS
27496	CONCLUSIONS
27497	OBJECTIVE
27498	METHODS
27499	METHODS
27500	METHODS
27501	RESULTS
27502	RESULTS
27503	RESULTS
27504	CONCLUSIONS
27505	CONCLUSIONS
27506	RESULTS
27507	OBJECTIVE
27508	METHODS
27509	METHODS
27510	METHODS
27511	METHODS
27512	METHODS
27513	METHODS
27514	METHODS
27515	METHODS
27516	RESULTS
27517	CONCLUSIONS
27518	CONCLUSIONS
27519	CONCLUSIONS
27520	OBJECTIVE
27521	METHODS
27522	METHODS
27523	METHODS
27524	METHODS
27525	RESULTS
27526	RESULTS
27527	RESULTS
27528	RESULTS
27529	CONCLUSIONS
27530	BACKGROUND
27531	OBJECTIVE
27532	METHODS
27533	METHODS
27534	METHODS
27535	RESULTS
27536	RESULTS
27537	RESULTS
27538	CONCLUSIONS
27539	BACKGROUND
27540	BACKGROUND
27541	BACKGROUND
27542	OBJECTIVE
27543	METHODS
27544	METHODS
27545	RESULTS
27546	RESULTS
27547	CONCLUSIONS
27548	CONCLUSIONS
27549	OBJECTIVE
27550	METHODS
27551	METHODS
27552	METHODS
27553	METHODS
27554	METHODS
27555	RESULTS
27556	RESULTS
27557	RESULTS
27558	RESULTS
27559	CONCLUSIONS
27560	CONCLUSIONS
27561	BACKGROUND
27562	BACKGROUND
27563	OBJECTIVE
27564	METHODS
27565	METHODS
27566	METHODS
27567	RESULTS
27568	RESULTS
27569	RESULTS
27570	CONCLUSIONS
27571	BACKGROUND
27572	OBJECTIVE
27573	METHODS
27574	METHODS
27575	METHODS
27576	METHODS
27577	METHODS
27578	METHODS
27579	METHODS
27580	RESULTS
27581	RESULTS
27582	CONCLUSIONS
27583	CONCLUSIONS
27584	OBJECTIVE
27585	OBJECTIVE
27586	OBJECTIVE
27587	BACKGROUND
27588	METHODS
27589	METHODS
27590	RESULTS
27591	RESULTS
27592	RESULTS
27593	RESULTS
27594	CONCLUSIONS
27595	CONCLUSIONS
27596	CONCLUSIONS
27597	BACKGROUND
27598	METHODS
27599	METHODS
27600	RESULTS
27601	RESULTS
27602	RESULTS
27603	RESULTS
27604	RESULTS
27605	RESULTS
27606	CONCLUSIONS
27607	CONCLUSIONS
27608	OBJECTIVE
27609	BACKGROUND
27610	BACKGROUND
27611	METHODS
27612	METHODS
27613	METHODS
27614	RESULTS
27615	RESULTS
27616	RESULTS
27617	CONCLUSIONS
27618	BACKGROUND
27619	BACKGROUND
27620	BACKGROUND
27621	OBJECTIVE
27622	METHODS
27623	METHODS
27624	CONCLUSIONS
27625	RESULTS
27626	CONCLUSIONS
27627	CONCLUSIONS
27628	OBJECTIVE
27629	METHODS
27630	METHODS
27631	METHODS
27632	METHODS
27633	METHODS
27634	METHODS
27635	METHODS
27636	METHODS
27637	RESULTS
27638	RESULTS
27639	RESULTS
27640	CONCLUSIONS
27641	OBJECTIVE
27642	METHODS
27643	METHODS
27644	METHODS
27645	METHODS
27646	RESULTS
27647	RESULTS
27648	RESULTS
27649	RESULTS
27650	BACKGROUND
27651	OBJECTIVE
27652	METHODS
27653	METHODS
27654	METHODS
27655	METHODS
27656	RESULTS
27657	RESULTS
27658	RESULTS
27659	RESULTS
27660	RESULTS
27661	RESULTS
27662	BACKGROUND
27663	METHODS
27664	METHODS
27665	METHODS
27666	RESULTS
27667	RESULTS
27668	RESULTS
27669	CONCLUSIONS
27670	CONCLUSIONS
27671	OBJECTIVE
27672	METHODS
27673	METHODS
27674	METHODS
27675	METHODS
27676	METHODS
27677	METHODS
27678	RESULTS
27679	RESULTS
27680	RESULTS
27681	RESULTS
27682	CONCLUSIONS
27683	OBJECTIVE
27684	METHODS
27685	METHODS
27686	METHODS
27687	METHODS
27688	METHODS
27689	RESULTS
27690	RESULTS
27691	RESULTS
27692	RESULTS
27693	RESULTS
27694	RESULTS
27695	BACKGROUND
27696	BACKGROUND
27697	OBJECTIVE
27698	METHODS
27699	METHODS
27700	METHODS
27701	METHODS
27702	METHODS
27703	METHODS
27704	METHODS
27705	METHODS
27706	METHODS
27707	METHODS
27708	RESULTS
27709	CONCLUSIONS
27710	RESULTS
27711	RESULTS
27712	CONCLUSIONS
27713	CONCLUSIONS
27714	BACKGROUND
27715	BACKGROUND
27716	BACKGROUND
27717	METHODS
27718	METHODS
27719	RESULTS
27720	RESULTS
27721	CONCLUSIONS
27722	CONCLUSIONS
27723	OBJECTIVE
27724	METHODS
27725	METHODS
27726	METHODS
27727	METHODS
27728	METHODS
27729	METHODS
27730	METHODS
27731	RESULTS
27732	RESULTS
27733	RESULTS
27734	RESULTS
27735	RESULTS
27736	CONCLUSIONS
27737	CONCLUSIONS
27738	CONCLUSIONS
27739	BACKGROUND
27740	OBJECTIVE
27741	METHODS
27742	METHODS
27743	METHODS
27744	METHODS
27745	RESULTS
27746	RESULTS
27747	RESULTS
27748	CONCLUSIONS
27749	CONCLUSIONS
27750	BACKGROUND
27751	OBJECTIVE
27752	METHODS
27753	METHODS
27754	METHODS
27755	METHODS
27756	METHODS
27757	METHODS
27758	RESULTS
27759	CONCLUSIONS
27760	BACKGROUND
27761	BACKGROUND
27762	BACKGROUND
27763	OBJECTIVE
27764	METHODS
27765	RESULTS
27766	RESULTS
27767	CONCLUSIONS
27768	OBJECTIVE
27769	METHODS
27770	METHODS
27771	METHODS
27772	METHODS
27773	METHODS
27774	METHODS
27775	METHODS
27776	RESULTS
27777	RESULTS
27778	RESULTS
27779	CONCLUSIONS
27780	BACKGROUND
27781	BACKGROUND
27782	BACKGROUND
27783	BACKGROUND
27784	METHODS
27785	METHODS
27786	METHODS
27787	METHODS
27788	CONCLUSIONS
27789	RESULTS
27790	RESULTS
27791	RESULTS
27792	RESULTS
27793	RESULTS
27794	BACKGROUND
27795	BACKGROUND
27796	OBJECTIVE
27797	OBJECTIVE
27798	METHODS
27799	METHODS
27800	METHODS
27801	METHODS
27802	METHODS
27803	RESULTS
27804	RESULTS
27805	CONCLUSIONS
27806	RESULTS
27807	CONCLUSIONS
27808	OBJECTIVE
27809	METHODS
27810	METHODS
27811	METHODS
27812	METHODS
27813	METHODS
27814	CONCLUSIONS
27815	RESULTS
27816	RESULTS
27817	RESULTS
27818	CONCLUSIONS
27819	OBJECTIVE
27820	METHODS
27821	METHODS
27822	METHODS
27823	RESULTS
27824	RESULTS
27825	RESULTS
27826	RESULTS
27827	RESULTS
27828	RESULTS
27829	CONCLUSIONS
27830	METHODS
27831	OBJECTIVE
27832	METHODS
27833	METHODS
27834	RESULTS
27835	RESULTS
27836	RESULTS
27837	OBJECTIVE
27838	CONCLUSIONS
27839	BACKGROUND
27840	BACKGROUND
27841	OBJECTIVE
27842	METHODS
27843	METHODS
27844	METHODS
27845	RESULTS
27846	RESULTS
27847	RESULTS
27848	RESULTS
27849	RESULTS
27850	CONCLUSIONS
27851	METHODS
27852	OBJECTIVE
27853	METHODS
27854	METHODS
27855	METHODS
27856	METHODS
27857	RESULTS
27858	RESULTS
27859	RESULTS
27860	RESULTS
27861	CONCLUSIONS
27862	OBJECTIVE
27863	METHODS
27864	METHODS
27865	RESULTS
27866	RESULTS
27867	RESULTS
27868	RESULTS
27869	RESULTS
27870	RESULTS
27871	CONCLUSIONS
27872	OBJECTIVE
27873	METHODS
27874	METHODS
27875	METHODS
27876	METHODS
27877	METHODS
27878	RESULTS
27879	RESULTS
27880	RESULTS
27881	RESULTS
27882	RESULTS
27883	CONCLUSIONS
27884	OBJECTIVE
27885	METHODS
27886	METHODS
27887	METHODS
27888	METHODS
27889	METHODS
27890	METHODS
27891	RESULTS
27892	CONCLUSIONS
27893	RESULTS
27894	RESULTS
27895	CONCLUSIONS
27896	CONCLUSIONS
27897	OBJECTIVE
27898	METHODS
27899	METHODS
27900	RESULTS
27901	RESULTS
27902	RESULTS
27903	RESULTS
27904	CONCLUSIONS
27905	BACKGROUND
27906	METHODS
27907	METHODS
27908	METHODS
27909	METHODS
27910	METHODS
27911	METHODS
27912	METHODS
27913	METHODS
27914	METHODS
27915	RESULTS
27916	RESULTS
27917	RESULTS
27918	CONCLUSIONS
27919	CONCLUSIONS
27920	BACKGROUND
27921	BACKGROUND
27922	OBJECTIVE
27923	METHODS
27924	METHODS
27925	RESULTS
27926	RESULTS
27927	RESULTS
27928	CONCLUSIONS
27929	BACKGROUND
27930	BACKGROUND
27931	OBJECTIVE
27932	METHODS
27933	RESULTS
27934	RESULTS
27935	RESULTS
27936	METHODS
27937	RESULTS
27938	CONCLUSIONS
27939	CONCLUSIONS
27940	OBJECTIVE
27941	METHODS
27942	METHODS
27943	METHODS
27944	METHODS
27945	RESULTS
27946	RESULTS
27947	RESULTS
27948	RESULTS
27949	RESULTS
27950	CONCLUSIONS
27951	CONCLUSIONS
27952	CONCLUSIONS
27953	BACKGROUND
27954	OBJECTIVE
27955	METHODS
27956	METHODS
27957	METHODS
27958	METHODS
27959	METHODS
27960	METHODS
27961	RESULTS
27962	RESULTS
27963	RESULTS
27964	CONCLUSIONS
27965	CONCLUSIONS
27966	BACKGROUND
27967	METHODS
27968	RESULTS
27969	RESULTS
27970	RESULTS
27971	RESULTS
27972	CONCLUSIONS
27973	CONCLUSIONS
27974	BACKGROUND
27975	OBJECTIVE
27976	METHODS
27977	METHODS
27978	METHODS
27979	METHODS
27980	RESULTS
27981	RESULTS
27982	CONCLUSIONS
27983	OBJECTIVE
27984	METHODS
27985	METHODS
27986	METHODS
27987	METHODS
27988	METHODS
27989	METHODS
27990	METHODS
27991	METHODS
27992	RESULTS
27993	RESULTS
27994	RESULTS
27995	RESULTS
27996	RESULTS
27997	RESULTS
27998	RESULTS
27999	RESULTS
28000	RESULTS
28001	RESULTS
28002	CONCLUSIONS
28003	OBJECTIVE
28004	METHODS
28005	METHODS
28006	METHODS
28007	METHODS
28008	RESULTS
28009	RESULTS
28010	RESULTS
28011	RESULTS
28012	RESULTS
28013	RESULTS
28014	CONCLUSIONS
28015	BACKGROUND
28016	BACKGROUND
28017	OBJECTIVE
28018	METHODS
28019	METHODS
28020	RESULTS
28021	RESULTS
28022	BACKGROUND
28023	BACKGROUND
28024	BACKGROUND
28025	BACKGROUND
28026	OBJECTIVE
28027	OBJECTIVE
28028	METHODS
28029	METHODS
28030	METHODS
28031	METHODS
28032	METHODS
28033	RESULTS
28034	RESULTS
28035	RESULTS
28036	RESULTS
28037	RESULTS
28038	RESULTS
28039	CONCLUSIONS
28040	RESULTS
28041	BACKGROUND
28042	BACKGROUND
28043	OBJECTIVE
28044	METHODS
28045	METHODS
28046	METHODS
28047	METHODS
28048	RESULTS
28049	CONCLUSIONS
28050	BACKGROUND
28051	BACKGROUND
28052	METHODS
28053	METHODS
28054	RESULTS
28055	RESULTS
28056	RESULTS
28057	RESULTS
28058	CONCLUSIONS
28059	CONCLUSIONS
28060	CONCLUSIONS
28061	OBJECTIVE
28062	METHODS
28063	METHODS
28064	METHODS
28065	METHODS
28066	METHODS
28067	RESULTS
28068	RESULTS
28069	RESULTS
28070	RESULTS
28071	RESULTS
28072	RESULTS
28073	RESULTS
28074	CONCLUSIONS
28075	OBJECTIVE
28076	METHODS
28077	METHODS
28078	METHODS
28079	METHODS
28080	METHODS
28081	RESULTS
28082	RESULTS
28083	RESULTS
28084	RESULTS
28085	CONCLUSIONS
28086	OBJECTIVE
28087	OBJECTIVE
28088	OBJECTIVE
28089	RESULTS
28090	METHODS
28091	RESULTS
28092	RESULTS
28093	RESULTS
28094	RESULTS
28095	CONCLUSIONS
28096	RESULTS
28097	CONCLUSIONS
28098	BACKGROUND
28099	OBJECTIVE
28100	OBJECTIVE
28101	METHODS
28102	METHODS
28103	METHODS
28104	RESULTS
28105	RESULTS
28106	RESULTS
28107	RESULTS
28108	CONCLUSIONS
28109	OBJECTIVE
28110	METHODS
28111	METHODS
28112	METHODS
28113	METHODS
28114	RESULTS
28115	RESULTS
28116	RESULTS
28117	RESULTS
28118	RESULTS
28119	CONCLUSIONS
28120	CONCLUSIONS
28121	OBJECTIVE
28122	METHODS
28123	METHODS
28124	METHODS
28125	RESULTS
28126	RESULTS
28127	CONCLUSIONS
28128	BACKGROUND
28129	BACKGROUND
28130	OBJECTIVE
28131	METHODS
28132	METHODS
28133	METHODS
28134	METHODS
28135	RESULTS
28136	RESULTS
28137	RESULTS
28138	CONCLUSIONS
28139	BACKGROUND
28140	OBJECTIVE
28141	METHODS
28142	METHODS
28143	METHODS
28144	RESULTS
28145	RESULTS
28146	RESULTS
28147	RESULTS
28148	RESULTS
28149	CONCLUSIONS
28150	OBJECTIVE
28151	OBJECTIVE
28152	METHODS
28153	METHODS
28154	METHODS
28155	RESULTS
28156	RESULTS
28157	RESULTS
28158	CONCLUSIONS
28159	RESULTS
28160	RESULTS
28161	RESULTS
28162	CONCLUSIONS
28163	RESULTS
28164	OBJECTIVE
28165	METHODS
28166	METHODS
28167	RESULTS
28168	RESULTS
28169	RESULTS
28170	CONCLUSIONS
28171	OBJECTIVE
28172	OBJECTIVE
28173	METHODS
28174	METHODS
28175	METHODS
28176	METHODS
28177	RESULTS
28178	RESULTS
28179	RESULTS
28180	RESULTS
28181	RESULTS
28182	RESULTS
28183	RESULTS
28184	CONCLUSIONS
28185	CONCLUSIONS
28186	BACKGROUND
28187	BACKGROUND
28188	BACKGROUND
28189	METHODS
28190	BACKGROUND
28191	OBJECTIVE
28192	METHODS
28193	METHODS
28194	METHODS
28195	RESULTS
28196	RESULTS
28197	RESULTS
28198	RESULTS
28199	CONCLUSIONS
28200	OBJECTIVE
28201	METHODS
28202	METHODS
28203	METHODS
28204	CONCLUSIONS
28205	CONCLUSIONS
28206	BACKGROUND
28207	BACKGROUND
28208	BACKGROUND
28209	METHODS
28210	METHODS
28211	METHODS
28212	METHODS
28213	RESULTS
28214	RESULTS
28215	RESULTS
28216	RESULTS
28217	CONCLUSIONS
28218	BACKGROUND
28219	CONCLUSIONS
28220	OBJECTIVE
28221	METHODS
28222	METHODS
28223	METHODS
28224	CONCLUSIONS
28225	RESULTS
28226	RESULTS
28227	RESULTS
28228	CONCLUSIONS
28229	CONCLUSIONS
28230	BACKGROUND
28231	BACKGROUND
28232	OBJECTIVE
28233	OBJECTIVE
28234	METHODS
28235	METHODS
28236	METHODS
28237	METHODS
28238	RESULTS
28239	RESULTS
28240	CONCLUSIONS
28241	RESULTS
28242	BACKGROUND
28243	BACKGROUND
28244	METHODS
28245	RESULTS
28246	RESULTS
28247	RESULTS
28248	RESULTS
28249	RESULTS
28250	CONCLUSIONS
28251	CONCLUSIONS
28252	BACKGROUND
28253	CONCLUSIONS
28254	METHODS
28255	METHODS
28256	RESULTS
28257	RESULTS
28258	RESULTS
28259	RESULTS
28260	RESULTS
28261	RESULTS
28262	RESULTS
28263	CONCLUSIONS
28264	CONCLUSIONS
28265	CONCLUSIONS
28266	OBJECTIVE
28267	CONCLUSIONS
28268	OBJECTIVE
28269	OBJECTIVE
28270	METHODS
28271	METHODS
28272	METHODS
28273	METHODS
28274	RESULTS
28275	RESULTS
28276	RESULTS
28277	CONCLUSIONS
28278	RESULTS
28279	CONCLUSIONS
28280	CONCLUSIONS
28281	OBJECTIVE
28282	METHODS
28283	METHODS
28284	METHODS
28285	RESULTS
28286	RESULTS
28287	CONCLUSIONS
28288	CONCLUSIONS
28289	BACKGROUND
28290	OBJECTIVE
28291	METHODS
28292	METHODS
28293	METHODS
28294	METHODS
28295	RESULTS
28296	RESULTS
28297	METHODS
28298	CONCLUSIONS
28299	OBJECTIVE
28300	OBJECTIVE
28301	METHODS
28302	METHODS
28303	METHODS
28304	METHODS
28305	BACKGROUND
28306	METHODS
28307	RESULTS
28308	RESULTS
28309	RESULTS
28310	CONCLUSIONS
28311	BACKGROUND
28312	BACKGROUND
28313	CONCLUSIONS
28314	OBJECTIVE
28315	METHODS
28316	METHODS
28317	METHODS
28318	METHODS
28319	RESULTS
28320	RESULTS
28321	RESULTS
28322	CONCLUSIONS
28323	OBJECTIVE
28324	METHODS
28325	METHODS
28326	METHODS
28327	METHODS
28328	RESULTS
28329	RESULTS
28330	RESULTS
28331	RESULTS
28332	CONCLUSIONS
28333	CONCLUSIONS
28334	BACKGROUND
28335	OBJECTIVE
28336	METHODS
28337	METHODS
28338	METHODS
28339	METHODS
28340	METHODS
28341	METHODS
28342	RESULTS
28343	RESULTS
28344	RESULTS
28345	RESULTS
28346	RESULTS
28347	CONCLUSIONS
28348	BACKGROUND
28349	BACKGROUND
28350	METHODS
28351	RESULTS
28352	RESULTS
28353	RESULTS
28354	RESULTS
28355	RESULTS
28356	CONCLUSIONS
28357	RESULTS
28358	CONCLUSIONS
28359	BACKGROUND
28360	BACKGROUND
28361	BACKGROUND
28362	OBJECTIVE
28363	METHODS
28364	METHODS
28365	METHODS
28366	RESULTS
28367	RESULTS
28368	RESULTS
28369	RESULTS
28370	CONCLUSIONS
28371	CONCLUSIONS
28372	RESULTS
28373	CONCLUSIONS
28374	OBJECTIVE
28375	METHODS
28376	METHODS
28377	METHODS
28378	METHODS
28379	METHODS
28380	METHODS
28381	METHODS
28382	RESULTS
28383	RESULTS
28384	RESULTS
28385	RESULTS
28386	RESULTS
28387	RESULTS
28388	RESULTS
28389	RESULTS
28390	RESULTS
28391	RESULTS
28392	RESULTS
28393	RESULTS
28394	RESULTS
28395	RESULTS
28396	CONCLUSIONS
28397	CONCLUSIONS
28398	BACKGROUND
28399	CONCLUSIONS
28400	BACKGROUND
28401	OBJECTIVE
28402	METHODS
28403	RESULTS
28404	RESULTS
28405	RESULTS
28406	RESULTS
28407	CONCLUSIONS
28408	BACKGROUND
28409	OBJECTIVE
28410	BACKGROUND
28411	METHODS
28412	METHODS
28413	RESULTS
28414	RESULTS
28415	RESULTS
28416	RESULTS
28417	CONCLUSIONS
28418	CONCLUSIONS
28419	BACKGROUND
28420	OBJECTIVE
28421	METHODS
28422	METHODS
28423	METHODS
28424	CONCLUSIONS
28425	CONCLUSIONS
28426	BACKGROUND
28427	BACKGROUND
28428	METHODS
28429	METHODS
28430	RESULTS
28431	RESULTS
28432	RESULTS
28433	RESULTS
28434	CONCLUSIONS
28435	CONCLUSIONS
28436	OBJECTIVE
28437	METHODS
28438	METHODS
28439	METHODS
28440	RESULTS
28441	RESULTS
28442	RESULTS
28443	RESULTS
28444	RESULTS
28445	RESULTS
28446	RESULTS
28447	OBJECTIVE
28448	METHODS
28449	METHODS
28450	RESULTS
28451	RESULTS
28452	RESULTS
28453	RESULTS
28454	CONCLUSIONS
28455	BACKGROUND
28456	METHODS
28457	METHODS
28458	RESULTS
28459	RESULTS
28460	RESULTS
28461	RESULTS
28462	CONCLUSIONS
28463	BACKGROUND
28464	OBJECTIVE
28465	METHODS
28466	METHODS
28467	METHODS
28468	METHODS
28469	METHODS
28470	METHODS
28471	METHODS
28472	CONCLUSIONS
28473	RESULTS
28474	RESULTS
28475	RESULTS
28476	CONCLUSIONS
28477	OBJECTIVE
28478	METHODS
28479	METHODS
28480	METHODS
28481	METHODS
28482	METHODS
28483	RESULTS
28484	RESULTS
28485	RESULTS
28486	RESULTS
28487	RESULTS
28488	RESULTS
28489	RESULTS
28490	RESULTS
28491	CONCLUSIONS
28492	RESULTS
28493	BACKGROUND
28494	BACKGROUND
28495	METHODS
28496	METHODS
28497	METHODS
28498	METHODS
28499	RESULTS
28500	RESULTS
28501	RESULTS
28502	RESULTS
28503	RESULTS
28504	RESULTS
28505	CONCLUSIONS
28506	CONCLUSIONS
28507	BACKGROUND
28508	BACKGROUND
28509	BACKGROUND
28510	BACKGROUND
28511	CONCLUSIONS
28512	METHODS
28513	METHODS
28514	METHODS
28515	RESULTS
28516	RESULTS
28517	RESULTS
28518	RESULTS
28519	RESULTS
28520	CONCLUSIONS
28521	METHODS
28522	METHODS
28523	METHODS
28524	RESULTS
28525	RESULTS
28526	RESULTS
28527	RESULTS
28528	RESULTS
28529	CONCLUSIONS
28530	CONCLUSIONS
28531	OBJECTIVE
28532	METHODS
28533	METHODS
28534	METHODS
28535	METHODS
28536	METHODS
28537	METHODS
28538	METHODS
28539	METHODS
28540	METHODS
28541	RESULTS
28542	RESULTS
28543	RESULTS
28544	RESULTS
28545	RESULTS
28546	RESULTS
28547	CONCLUSIONS
28548	CONCLUSIONS
28549	OBJECTIVE
28550	METHODS
28551	METHODS
28552	RESULTS
28553	RESULTS
28554	METHODS
28555	RESULTS
28556	RESULTS
28557	RESULTS
28558	RESULTS
28559	CONCLUSIONS
28560	BACKGROUND
28561	BACKGROUND
28562	BACKGROUND
28563	OBJECTIVE
28564	METHODS
28565	METHODS
28566	METHODS
28567	RESULTS
28568	CONCLUSIONS
28569	CONCLUSIONS
28570	OBJECTIVE
28571	METHODS
28572	METHODS
28573	METHODS
28574	METHODS
28575	METHODS
28576	RESULTS
28577	CONCLUSIONS
28578	BACKGROUND
28579	OBJECTIVE
28580	METHODS
28581	METHODS
28582	CONCLUSIONS
28583	RESULTS
28584	CONCLUSIONS
28585	RESULTS
28586	CONCLUSIONS
28587	CONCLUSIONS
28588	BACKGROUND
28589	BACKGROUND
28590	OBJECTIVE
28591	METHODS
28592	METHODS
28593	METHODS
28594	RESULTS
28595	RESULTS
28596	CONCLUSIONS
28597	CONCLUSIONS
28598	CONCLUSIONS
28599	BACKGROUND
28600	BACKGROUND
28601	METHODS
28602	METHODS
28603	METHODS
28604	METHODS
28605	RESULTS
28606	RESULTS
28607	RESULTS
28608	RESULTS
28609	RESULTS
28610	RESULTS
28611	RESULTS
28612	CONCLUSIONS
28613	CONCLUSIONS
28614	BACKGROUND
28615	METHODS
28616	METHODS
28617	METHODS
28618	METHODS
28619	METHODS
28620	RESULTS
28621	RESULTS
28622	RESULTS
28623	RESULTS
28624	RESULTS
28625	CONCLUSIONS
28626	BACKGROUND
28627	OBJECTIVE
28628	METHODS
28629	METHODS
28630	METHODS
28631	METHODS
28632	METHODS
28633	METHODS
28634	RESULTS
28635	RESULTS
28636	CONCLUSIONS
28637	CONCLUSIONS
28638	BACKGROUND
28639	BACKGROUND
28640	BACKGROUND
28641	METHODS
28642	METHODS
28643	METHODS
28644	METHODS
28645	METHODS
28646	RESULTS
28647	RESULTS
28648	RESULTS
28649	RESULTS
28650	RESULTS
28651	RESULTS
28652	RESULTS
28653	CONCLUSIONS
28654	BACKGROUND
28655	OBJECTIVE
28656	BACKGROUND
28657	BACKGROUND
28658	METHODS
28659	METHODS
28660	METHODS
28661	METHODS
28662	METHODS
28663	METHODS
28664	METHODS
28665	CONCLUSIONS
28666	RESULTS
28667	CONCLUSIONS
28668	CONCLUSIONS
28669	CONCLUSIONS
28670	OBJECTIVE
28671	METHODS
28672	METHODS
28673	RESULTS
28674	RESULTS
28675	CONCLUSIONS
28676	BACKGROUND
28677	BACKGROUND
28678	BACKGROUND
28679	METHODS
28680	METHODS
28681	METHODS
28682	METHODS
28683	METHODS
28684	METHODS
28685	METHODS
28686	METHODS
28687	RESULTS
28688	RESULTS
28689	RESULTS
28690	RESULTS
28691	RESULTS
28692	RESULTS
28693	RESULTS
28694	RESULTS
28695	CONCLUSIONS
28696	BACKGROUND
28697	METHODS
28698	OBJECTIVE
28699	BACKGROUND
28700	METHODS
28701	METHODS
28702	METHODS
28703	METHODS
28704	METHODS
28705	RESULTS
28706	RESULTS
28707	RESULTS
28708	RESULTS
28709	RESULTS
28710	RESULTS
28711	RESULTS
28712	CONCLUSIONS
28713	CONCLUSIONS
28714	METHODS
28715	OBJECTIVE
28716	METHODS
28717	METHODS
28718	METHODS
28719	METHODS
28720	METHODS
28721	METHODS
28722	RESULTS
28723	CONCLUSIONS
28724	RESULTS
28725	OBJECTIVE
28726	BACKGROUND
28727	METHODS
28728	METHODS
28729	RESULTS
28730	RESULTS
28731	RESULTS
28732	RESULTS
28733	RESULTS
28734	RESULTS
28735	RESULTS
28736	CONCLUSIONS
28737	CONCLUSIONS
28738	CONCLUSIONS
28739	BACKGROUND
28740	METHODS
28741	METHODS
28742	METHODS
28743	METHODS
28744	METHODS
28745	RESULTS
28746	RESULTS
28747	RESULTS
28748	RESULTS
28749	CONCLUSIONS
28750	CONCLUSIONS
28751	BACKGROUND
28752	BACKGROUND
28753	OBJECTIVE
28754	METHODS
28755	METHODS
28756	METHODS
28757	METHODS
28758	METHODS
28759	METHODS
28760	RESULTS
28761	RESULTS
28762	RESULTS
28763	RESULTS
28764	RESULTS
28765	CONCLUSIONS
28766	OBJECTIVE
28767	METHODS
28768	METHODS
28769	METHODS
28770	METHODS
28771	RESULTS
28772	RESULTS
28773	RESULTS
28774	RESULTS
28775	RESULTS
28776	RESULTS
28777	CONCLUSIONS
28778	BACKGROUND
28779	OBJECTIVE
28780	METHODS
28781	METHODS
28782	METHODS
28783	METHODS
28784	METHODS
28785	RESULTS
28786	RESULTS
28787	RESULTS
28788	CONCLUSIONS
28789	CONCLUSIONS
28790	OBJECTIVE
28791	METHODS
28792	METHODS
28793	METHODS
28794	RESULTS
28795	RESULTS
28796	RESULTS
28797	RESULTS
28798	RESULTS
28799	CONCLUSIONS
28800	METHODS
28801	METHODS
28802	RESULTS
28803	RESULTS
28804	RESULTS
28805	RESULTS
28806	RESULTS
28807	RESULTS
28808	CONCLUSIONS
28809	OBJECTIVE
28810	METHODS
28811	METHODS
28812	METHODS
28813	METHODS
28814	RESULTS
28815	RESULTS
28816	RESULTS
28817	RESULTS
28818	RESULTS
28819	CONCLUSIONS
28820	CONCLUSIONS
28821	BACKGROUND
28822	BACKGROUND
28823	METHODS
28824	METHODS
28825	METHODS
28826	METHODS
28827	METHODS
28828	RESULTS
28829	RESULTS
28830	RESULTS
28831	RESULTS
28832	RESULTS
28833	RESULTS
28834	CONCLUSIONS
28835	BACKGROUND
28836	BACKGROUND
28837	BACKGROUND
28838	RESULTS
28839	METHODS
28840	METHODS
28841	METHODS
28842	METHODS
28843	METHODS
28844	METHODS
28845	RESULTS
28846	RESULTS
28847	RESULTS
28848	RESULTS
28849	CONCLUSIONS
28850	CONCLUSIONS
28851	OBJECTIVE
28852	METHODS
28853	METHODS
28854	METHODS
28855	METHODS
28856	RESULTS
28857	RESULTS
28858	RESULTS
28859	RESULTS
28860	CONCLUSIONS
28861	OBJECTIVE
28862	METHODS
28863	METHODS
28864	METHODS
28865	METHODS
28866	METHODS
28867	METHODS
28868	RESULTS
28869	RESULTS
28870	RESULTS
28871	RESULTS
28872	CONCLUSIONS
28873	CONCLUSIONS
28874	BACKGROUND
28875	BACKGROUND
28876	METHODS
28877	METHODS
28878	RESULTS
28879	RESULTS
28880	RESULTS
28881	RESULTS
28882	RESULTS
28883	CONCLUSIONS
28884	RESULTS
28885	CONCLUSIONS
28886	OBJECTIVE
28887	BACKGROUND
28888	METHODS
28889	METHODS
28890	RESULTS
28891	RESULTS
28892	RESULTS
28893	RESULTS
28894	RESULTS
28895	CONCLUSIONS
28896	CONCLUSIONS
28897	BACKGROUND
28898	BACKGROUND
28899	OBJECTIVE
28900	METHODS
28901	METHODS
28902	METHODS
28903	METHODS
28904	METHODS
28905	METHODS
28906	METHODS
28907	RESULTS
28908	RESULTS
28909	CONCLUSIONS
28910	RESULTS
28911	RESULTS
28912	CONCLUSIONS
28913	CONCLUSIONS
28914	BACKGROUND
28915	BACKGROUND
28916	METHODS
28917	RESULTS
28918	METHODS
28919	METHODS
28920	METHODS
28921	RESULTS
28922	RESULTS
28923	RESULTS
28924	RESULTS
28925	RESULTS
28926	RESULTS
28927	CONCLUSIONS
28928	METHODS
28929	RESULTS
28930	RESULTS
28931	OBJECTIVE
28932	RESULTS
28933	METHODS
28934	RESULTS
28935	RESULTS
28936	RESULTS
28937	RESULTS
28938	CONCLUSIONS
28939	CONCLUSIONS
28940	BACKGROUND
28941	CONCLUSIONS
28942	BACKGROUND
28943	RESULTS
28944	RESULTS
28945	CONCLUSIONS
28946	BACKGROUND
28947	METHODS
28948	METHODS
28949	METHODS
28950	METHODS
28951	METHODS
28952	METHODS
28953	BACKGROUND
28954	OBJECTIVE
28955	METHODS
28956	METHODS
28957	RESULTS
28958	RESULTS
28959	RESULTS
28960	CONCLUSIONS
28961	CONCLUSIONS
28962	CONCLUSIONS
28963	OBJECTIVE
28964	METHODS
28965	METHODS
28966	METHODS
28967	METHODS
28968	METHODS
28969	RESULTS
28970	RESULTS
28971	RESULTS
28972	CONCLUSIONS
28973	BACKGROUND
28974	BACKGROUND
28975	METHODS
28976	METHODS
28977	METHODS
28978	RESULTS
28979	METHODS
28980	METHODS
28981	RESULTS
28982	RESULTS
28983	RESULTS
28984	RESULTS
28985	RESULTS
28986	RESULTS
28987	CONCLUSIONS
28988	OBJECTIVE
28989	METHODS
28990	METHODS
28991	METHODS
28992	METHODS
28993	RESULTS
28994	RESULTS
28995	RESULTS
28996	RESULTS
28997	CONCLUSIONS
28998	CONCLUSIONS
28999	BACKGROUND
29000	BACKGROUND
29001	OBJECTIVE
29002	METHODS
29003	METHODS
29004	METHODS
29005	METHODS
29006	RESULTS
29007	RESULTS
29008	RESULTS
29009	RESULTS
29010	CONCLUSIONS
29011	CONCLUSIONS
29012	CONCLUSIONS
29013	OBJECTIVE
29014	METHODS
29015	METHODS
29016	METHODS
29017	METHODS
29018	RESULTS
29019	RESULTS
29020	RESULTS
29021	CONCLUSIONS
29022	OBJECTIVE
29023	BACKGROUND
29024	OBJECTIVE
29025	METHODS
29026	METHODS
29027	METHODS
29028	RESULTS
29029	CONCLUSIONS
29030	CONCLUSIONS
29031	OBJECTIVE
29032	METHODS
29033	METHODS
29034	RESULTS
29035	RESULTS
29036	METHODS
29037	RESULTS
29038	RESULTS
29039	RESULTS
29040	CONCLUSIONS
29041	RESULTS
29042	RESULTS
29043	OBJECTIVE
29044	METHODS
29045	METHODS
29046	METHODS
29047	METHODS
29048	METHODS
29049	METHODS
29050	METHODS
29051	METHODS
29052	RESULTS
29053	RESULTS
29054	CONCLUSIONS
29055	OBJECTIVE
29056	METHODS
29057	METHODS
29058	METHODS
29059	METHODS
29060	METHODS
29061	METHODS
29062	METHODS
29063	METHODS
29064	METHODS
29065	RESULTS
29066	METHODS
29067	RESULTS
29068	RESULTS
29069	CONCLUSIONS
29070	CONCLUSIONS
29071	OBJECTIVE
29072	METHODS
29073	METHODS
29074	RESULTS
29075	RESULTS
29076	RESULTS
29077	RESULTS
29078	RESULTS
29079	CONCLUSIONS
29080	CONCLUSIONS
29081	CONCLUSIONS
29082	BACKGROUND
29083	BACKGROUND
29084	OBJECTIVE
29085	BACKGROUND
29086	OBJECTIVE
29087	METHODS
29088	METHODS
29089	METHODS
29090	RESULTS
29091	RESULTS
29092	RESULTS
29093	RESULTS
29094	CONCLUSIONS
29095	CONCLUSIONS
29096	BACKGROUND
29097	BACKGROUND
29098	METHODS
29099	RESULTS
29100	RESULTS
29101	RESULTS
29102	RESULTS
29103	RESULTS
29104	RESULTS
29105	CONCLUSIONS
29106	CONCLUSIONS
29107	BACKGROUND
29108	BACKGROUND
29109	METHODS
29110	METHODS
29111	METHODS
29112	METHODS
29113	METHODS
29114	METHODS
29115	METHODS
29116	RESULTS
29117	RESULTS
29118	RESULTS
29119	RESULTS
29120	CONCLUSIONS
29121	BACKGROUND
29122	BACKGROUND
29123	OBJECTIVE
29124	METHODS
29125	METHODS
29126	RESULTS
29127	RESULTS
29128	RESULTS
29129	RESULTS
29130	RESULTS
29131	CONCLUSIONS
29132	OBJECTIVE
29133	METHODS
29134	METHODS
29135	METHODS
29136	METHODS
29137	METHODS
29138	METHODS
29139	METHODS
29140	METHODS
29141	RESULTS
29142	RESULTS
29143	CONCLUSIONS
29144	CONCLUSIONS
29145	OBJECTIVE
29146	METHODS
29147	METHODS
29148	METHODS
29149	METHODS
29150	RESULTS
29151	RESULTS
29152	RESULTS
29153	RESULTS
29154	RESULTS
29155	RESULTS
29156	CONCLUSIONS
29157	BACKGROUND
29158	BACKGROUND
29159	METHODS
29160	METHODS
29161	METHODS
29162	METHODS
29163	METHODS
29164	RESULTS
29165	RESULTS
29166	RESULTS
29167	CONCLUSIONS
29168	CONCLUSIONS
29169	OBJECTIVE
29170	METHODS
29171	METHODS
29172	METHODS
29173	METHODS
29174	METHODS
29175	METHODS
29176	RESULTS
29177	RESULTS
29178	RESULTS
29179	RESULTS
29180	CONCLUSIONS
29181	CONCLUSIONS
29182	OBJECTIVE
29183	METHODS
29184	METHODS
29185	METHODS
29186	METHODS
29187	RESULTS
29188	RESULTS
29189	CONCLUSIONS
29190	OBJECTIVE
29191	METHODS
29192	METHODS
29193	METHODS
29194	METHODS
29195	METHODS
29196	RESULTS
29197	RESULTS
29198	RESULTS
29199	RESULTS
29200	RESULTS
29201	CONCLUSIONS
29202	CONCLUSIONS
29203	OBJECTIVE
29204	OBJECTIVE
29205	METHODS
29206	METHODS
29207	METHODS
29208	METHODS
29209	METHODS
29210	RESULTS
29211	RESULTS
29212	CONCLUSIONS
29213	BACKGROUND
29214	BACKGROUND
29215	BACKGROUND
29216	OBJECTIVE
29217	METHODS
29218	RESULTS
29219	RESULTS
29220	CONCLUSIONS
29221	OBJECTIVE
29222	METHODS
29223	METHODS
29224	METHODS
29225	METHODS
29226	METHODS
29227	METHODS
29228	OBJECTIVE
29229	RESULTS
29230	RESULTS
29231	RESULTS
29232	RESULTS
29233	RESULTS
29234	RESULTS
29235	RESULTS
29236	CONCLUSIONS
29237	CONCLUSIONS
29238	OBJECTIVE
29239	METHODS
29240	METHODS
29241	METHODS
29242	METHODS
29243	METHODS
29244	METHODS
29245	METHODS
29246	RESULTS
29247	RESULTS
29248	CONCLUSIONS
29249	OBJECTIVE
29250	OBJECTIVE
29251	OBJECTIVE
29252	METHODS
29253	METHODS
29254	METHODS
29255	RESULTS
29256	RESULTS
29257	RESULTS
29258	RESULTS
29259	CONCLUSIONS
29260	BACKGROUND
29261	METHODS
29262	METHODS
29263	RESULTS
29264	RESULTS
29265	RESULTS
29266	RESULTS
29267	RESULTS
29268	RESULTS
29269	RESULTS
29270	CONCLUSIONS
29271	BACKGROUND
29272	BACKGROUND
29273	OBJECTIVE
29274	METHODS
29275	METHODS
29276	METHODS
29277	RESULTS
29278	BACKGROUND
29279	BACKGROUND
29280	CONCLUSIONS
29281	BACKGROUND
29282	OBJECTIVE
29283	METHODS
29284	RESULTS
29285	RESULTS
29286	CONCLUSIONS
29287	BACKGROUND
29288	BACKGROUND
29289	BACKGROUND
29290	METHODS
29291	RESULTS
29292	RESULTS
29293	CONCLUSIONS
29294	CONCLUSIONS
29295	OBJECTIVE
29296	METHODS
29297	METHODS
29298	METHODS
29299	METHODS
29300	METHODS
29301	RESULTS
29302	CONCLUSIONS
29303	RESULTS
29304	RESULTS
29305	RESULTS
29306	CONCLUSIONS
29307	RESULTS
29308	BACKGROUND
29309	BACKGROUND
29310	OBJECTIVE
29311	METHODS
29312	METHODS
29313	RESULTS
29314	RESULTS
29315	RESULTS
29316	RESULTS
29317	RESULTS
29318	OBJECTIVE
29319	METHODS
29320	METHODS
29321	METHODS
29322	RESULTS
29323	METHODS
29324	RESULTS
29325	RESULTS
29326	RESULTS
29327	RESULTS
29328	RESULTS
29329	CONCLUSIONS
29330	BACKGROUND
29331	BACKGROUND
29332	CONCLUSIONS
29333	BACKGROUND
29334	BACKGROUND
29335	METHODS
29336	METHODS
29337	METHODS
29338	METHODS
29339	METHODS
29340	METHODS
29341	METHODS
29342	RESULTS
29343	RESULTS
29344	RESULTS
29345	CONCLUSIONS
29346	CONCLUSIONS
29347	BACKGROUND
29348	BACKGROUND
29349	BACKGROUND
29350	BACKGROUND
29351	BACKGROUND
29352	METHODS
29353	METHODS
29354	METHODS
29355	METHODS
29356	METHODS
29357	METHODS
29358	CONCLUSIONS
29359	BACKGROUND
29360	CONCLUSIONS
29361	BACKGROUND
29362	OBJECTIVE
29363	METHODS
29364	METHODS
29365	METHODS
29366	METHODS
29367	METHODS
29368	METHODS
29369	RESULTS
29370	RESULTS
29371	RESULTS
29372	CONCLUSIONS
29373	RESULTS
29374	OBJECTIVE
29375	METHODS
29376	METHODS
29377	METHODS
29378	RESULTS
29379	RESULTS
29380	CONCLUSIONS
29381	BACKGROUND
29382	BACKGROUND
29383	METHODS
29384	METHODS
29385	RESULTS
29386	RESULTS
29387	CONCLUSIONS
29388	CONCLUSIONS
29389	CONCLUSIONS
29390	BACKGROUND
29391	BACKGROUND
29392	BACKGROUND
29393	METHODS
29394	RESULTS
29395	RESULTS
29396	RESULTS
29397	RESULTS
29398	RESULTS
29399	BACKGROUND
29400	OBJECTIVE
29401	METHODS
29402	METHODS
29403	RESULTS
29404	RESULTS
29405	RESULTS
29406	RESULTS
29407	CONCLUSIONS
29408	BACKGROUND
29409	BACKGROUND
29410	OBJECTIVE
29411	METHODS
29412	METHODS
29413	METHODS
29414	RESULTS
29415	RESULTS
29416	CONCLUSIONS
29417	OBJECTIVE
29418	METHODS
29419	METHODS
29420	METHODS
29421	METHODS
29422	METHODS
29423	METHODS
29424	RESULTS
29425	RESULTS
29426	CONCLUSIONS
29427	BACKGROUND
29428	BACKGROUND
29429	METHODS
29430	METHODS
29431	RESULTS
29432	RESULTS
29433	CONCLUSIONS
29434	CONCLUSIONS
29435	BACKGROUND
29436	BACKGROUND
29437	OBJECTIVE
29438	METHODS
29439	METHODS
29440	METHODS
29441	METHODS
29442	METHODS
29443	RESULTS
29444	CONCLUSIONS
29445	OBJECTIVE
29446	METHODS
29447	METHODS
29448	RESULTS
29449	RESULTS
29450	RESULTS
29451	RESULTS
29452	CONCLUSIONS
29453	OBJECTIVE
29454	METHODS
29455	METHODS
29456	METHODS
29457	METHODS
29458	METHODS
29459	RESULTS
29460	RESULTS
29461	RESULTS
29462	CONCLUSIONS
29463	CONCLUSIONS
29464	CONCLUSIONS
29465	OBJECTIVE
29466	METHODS
29467	METHODS
29468	METHODS
29469	RESULTS
29470	RESULTS
29471	RESULTS
29472	RESULTS
29473	CONCLUSIONS
29474	BACKGROUND
29475	OBJECTIVE
29476	METHODS
29477	METHODS
29478	RESULTS
29479	RESULTS
29480	CONCLUSIONS
29481	BACKGROUND
29482	OBJECTIVE
29483	METHODS
29484	METHODS
29485	METHODS
29486	RESULTS
29487	RESULTS
29488	RESULTS
29489	RESULTS
29490	RESULTS
29491	CONCLUSIONS
29492	CONCLUSIONS