#version: 0.2 - Trained by `huggingface/tokenizers` i n Ġ a Ġ t r e o n t i h e e n Ġ o e r Ġ s a l Ġ c e d Ġ p Ġt he Ġ in Ġa n a t Ġo f e s Ġ w o r r o a n ti on i s i t Ġan d Ġ m i c Ġ d a s Ġ f a r Ġ b in g en t Ġ re l e a tion Ġ e v e Ġt o e c o m u l Ġ ( u s a c l y o s Ġ T e t Ġ h o l i d Ġ n u r Ġt h it h i m Ġ l Ġw ith e l e re u n Ġ g t er a ti t r i g c e Ġp ro Ġf or i l Ġc on re s o t Ġ C u c Ġ A i f ĠT he r a u t Ġs t at ed o d Ġ v o c u m ti c o p Ġa s o w t s Ġw as it y m ent Ġe x Ġ is s i a m Ġw ere at e Ġ I o g Ġ 1 Ġ on e m u d i r Ġre s Ġc om a b a g y s Ġ P Ġa c Ġ S ic al ent s v er el l Ġth at ro m Ġb e Ġb y Ġ r t h u p Ġ M an t in e q u p h f f as e Ġa l Ġc h u re ti ve t ed d i a in Ġd e s e Ġp ati Ġ 2 he r Ġcom p Ġ im Ġd is Ġo r i b es s Ġ H p ec p l a d Ġ R t e Ġ us Ġpati ents er s un d Ġst ud Ġin c d uc Ġa t Ġf rom i z Ġ D Ġa d i al Ġa re ig n ve l re d i es p er si on Ġc ell ig h ation s u g u b Ġ he r an if ic Ġ B a y Ġs e i p Ġn e Ġ en p or ĠI n or m o re o us Ġw h en ce ti v ff ec Ġ le ) . c h i on Ġp er t or Ġas s Ġ E Ġs h es t Ġ W ar y g e i a Ġ N Ġ F Ġ O le c ol og s t t ro ul ar Ġd i Ġg en ) , re at Ġp re Ġg ro Ġin f ati ve re n 0 0 Ġs ign if f i v Ġ 0 re as Ġ 3 an d an c Ġc l y p p res en ti Ġm et a p Ġb et ere n Ġd iff an ce Ġstud y e ar Ġa p Ġth is os t ag e Ġc o y l p ro Ġw e Ġe ffec is t tion s Ġin ter Ġe v Ġ L Ġp h w e O N Ġt ran on g Ġp res Ġn ot Ġh a t her ic h Ġp l Ġp ar Ġan al e p v i Ġ G Ġm od os e Ġs ur on s id e Ġre c Ġ k oc i Ġsign ific un c d ing Ġdiff eren i ed at h Ġo b Ġs tr Ġa b Ġgro up Ġs ub Ġcell s ĠT h Ġre g Ġtran s al ly we en reat ment ab le i ti Ġsignific ant al l Ġbet ween Ġd et y n v ed ra p Ġres ul por t en c l ow as t Ġm e on e f ter ys t ar i Ġac tiv Ġ it en d Ġs pec Ġ 4 te in al u Ġwh ich Ġha ve Ġ y Ġsh ow Ġm ic Ġs c m in Ġ 5 f orm Ġt reatment at es o und ti m ĠW e ec h Ġin v Ġ = Ġcon s Ġin t Ġre l Ġc or Ġc a he n o x t al Ġin d Ġf ac at or il ity os is igh t om e N A ro s il l Ġc ar Ġa fter Ġh igh ul ation Ġ und Ġth an duc ed o ur ec tion k e en s y m Ġass oci m un Ġan ti p on ot h Ġle vel c l pres sion r i vel op Ġ un tro l o od ac t Ġ ro ys is Ġdis e as s u al Ġa r e w t ain re e Ġus ing Ġpro tein ac ter ur ing Ġc an u e reas ed ug h ac h at ing ĠTh is Ġa g as es w o p le ce p E S unc tion Ġb i ent r Ġa m in ical o b yst em Ġp o at er Ġh as Ġde velop an g l u Ġ qu Ġthe se h ib y t m s ag n Ġ 6 Ġn o olog ical Ġbe en o ut ati c Ġmet h al th Ġl ow v en t ing Ġp os Ġb ut a red Ġm ed Ġcon trol d er Ġresul ts u res p os Ġb l at a og en g en s o Ġthe ir Ġp r Ġd ec Ġ U he m iz ed c ess Ġus ed Ġm ay Ġs ystem c r Ġo ut Ġm on Ġh y v id Ġinc l Ġc ol Ġfac tor t en as ed Ġt wo Ġs up Ġs p Ġal l I ON Ġm an Ġt r Ġmod el Ġv ari Ġd uring Ġal so Ġs er ac e ul d Ġdise ase Ġh ad Ġcl inical iz ation s er Ġd es Ġ 9 anc er Ġanal ysis T S Ġt im re l pec tive is k Ġf ol Ġ id il d Ġincl ud enti f C L Ġm ore 0 1 Ġund er am in Ġ ra Ġassoci ated ul t Ġb oth Ġhe alth Ġm o d e E T Ġme as e ver uc t Ġpres ent or s Ġd ata ic i Ġs yn hib it Ġf unction Ġy ear i tion Ġcon c m on Ġmeth od og ra j ec Ġus e in ding Ġn on a k Ġac c i um ar d U S Ġex pression an ts an s Ġs uc it e Ġgen e Ġactiv ity Ġe m in al Ġs ug n e Ġ 7 Ġthe rap a ys ator y di tion Ġ V i le Ġs am Ġsignificant ly Ġper form O D o id yp e Ġcomp le Ġev alu Ġid entif r ic Ġo ver Ġr isk Ġres pon Ġfol low Ġc ancer Ġp ot Ġo ther ti g Ġh um Ġp ath Ġinc reased u tion Ġsug g ac tion a il re c Ġlevel s t om Ġcomp ared Ġs im enti al ter n b le Ġstud ies Ġen d duc tion on d or k Ġdet er Ġg l Ġeffec ts Ġh ig Ġob ser Ġ + olog y Ġim mun ĠC ON ic ation Ġf ound ere d Ġit s t in U L ] . Ġex per i ver C T Ġch ar si ve Ġo p Ġdifferen t ab ility enc y Ġt um Ġd em m a Ġ 8 US ION CL USION ĠCON CLUSION Ġeffec t Ġpro g ĠR ES Ġdi agn tic al Ġtim e Ġshow ed us ion ogra ph r on Ġass ess ment s ow ever ĠRES UL om a es tig Ġap pro Ġfor m ar g ly m Ġd r ĠRESUL TS er y ' s iti es ech an ur ren em b l es is m Ġmic ro ons tr Ġw he Ġyear s c es it al er g vi ew Ġinv estig id ence he d Ġ1 0 i tive ut e he s op h ra in Ġin s p ar i ve v al Ġm ul is s Ġpar tic at ure Ġind ic i qu Ġhum an ĠM ET Ġ up re ase al e Ġre m Ġp red Ġim pro H OD Ġint o Ġac id Ġon e Ġmeas ure Ġm a ĠMET HOD Ġo c N D tr ib ĠA l c op res s Ġwh o ur al Ġchar acter Ġhig her Ġm echan ar k ti l c in or d % ) u ro Ġr at Ġa ge ac k Ġ < Ġconc entr orm al Ġm ost Ġ K Ġin hibit Ġw ell b in Ġde f e x l ic l ed Ġin tr Ġch ild Ġne w Ġsur g d ro un g ĠMETHOD S um b I V ti t Ġstr uct ro ugh A C n al a v Ġs ec pective ly Ġpati ent m ed Ġm or cep tor Ġe lec ĠThe se Ġ es Ġp ost an ge Ġgen er Ġim port or t Ġe p end ent Ġgroup s et h p a i x us e ech n ation al tic s ow n ph a ir st Ġca re Ġc ases Ġs m o k Ġm in Ġpro cess Ġr ate Ġdevelop ment ur ther Ġdem onstr Ġe ff Ġobser ved Ġch ang Ġfactor s s y Ġsuc h Ġl oc in es f er r y am m Ġon ly Ġro le Ġgro w Ġbl ood Ġt iss en e as c Ġrespon se Ġpot ential os ph Ġt est uc le Ġv alu ol d ul ated al s en si Ġt echn ot he is e a re os p ĠH owever om en Ġthe re Ġth ree Ġoc c om es Ġo x tiv ity ar ly tain ed Ġpred ic f ul o v Ġf irst Ġdr ug o res pres s ion s Ġcon f ĠT o h y ra m Ġres pectively Ġth rough Ġp op er ative Ġout c Ġre view re ated ent al an e Ġre ceptor por ted Ġtherap y Ġw hen c o A T f ore h a iv ed Ġmul ti Ġam ong urren t Ġto tal Ġ [ i ke ec ted Ġmo lec Ġpr im Ġf e i e i od ym p Ġsugg est g an o ugh ep endent Ġc al Ġap pl Ġinv ol Ġth ose 1 0 z ed Ġp a Ġk n it s Ġn umb Ġchang es or y Ġcor rel iz e o uld Ġv ir ven tion Ġ1 9 R O Ġh yp Ġl ong Ġ1 2 f t Ġc yt ĠS t re qu Ġs ol Ġperform ed arg et ab ol Ġm ut od y Ġex amin qu i Ġinc rease Ġco uld th s Ġspec ific / - al ity Ġchild ren oc k i an Ġad dition Ġm us Ġdeter min Ġa ut Ġc r osp ital e k x im ti es ĠA n cr ib Ġimport ant Ġb as Ġin j l as ĠThe re Ġra di Ġtum or ent ly ag es iv al Ġex tr ar ge u es Ġlow er ar t Ġf inding Ġhy per Ġm ain ĠC h Ġgrow th ymp tom Ġinclud ing asc ular Ġin di n ess R NA Ġse qu Ġexper im Ġcar di Ġw ork at al Ġc ase Ġcomple x ain s Ġanti b Ġre ve ac y ic e Ġn ormal it er Ġcom bin Ġpl as Ġm y re g Ġwith in Ġnumb er it ro ar di n ing Ġdis c Ġne uro Ġse lec cr ip ros s Ġm emb in d I I Ġcon t Ġf ib i ly il ar ha vi Ġpro m ĠCONCLUSION S Ġw omen Ġ J Ġidentif ied i el et y ir on Ġt arget Ġne ed Ġo ur in t it ed Ġ j c le Ġc hem o ver vid ual Ġa ffec Ġb ased Ġd el Ġ - Ġmic e Ġpro t is tr Ġt ype Ġmet abol ĠD NA er v in s Ġg ra ing le Ġf requ Ġsub jec iti s si ble er c Ġl im Ġper iod Ġc ap ear ch z ym op erative h ip ograph y Ġwith out t y en g i or Ġ2 0 l amm vi ous b ased Ġp at Ġres p Ġre ported Ġmon ths Ġpro vid Ġcom mon is h iel d Ġm al e tic Ġsur v is ms Ġf lu pl es 0 5 Ġcons id Ġreve al ate g Ġre qui 1 9 Ġca us Ġex pl es ted Ġd o ati s Ġs tim og n j or Ġme an res sion ical ly Ġap p T he Ġ2 01 Ġex pos ag ing o tic Ġanal y Ġfinding s am et rec t Ġbe havi ti s Ġl ess Ġinf lu in duced b r 1 2 hes is Ġhe m Ġa im a f % , Ġtiss ue Ġt ra ĠI t Ġdiagn osis Ġs ymptom Ġcal c if ied am ic f ace Ġindi vidual R I ul ts Ġe ach er ation ĠC I Ġcon tr Ġre f oc yt Ġdes crib Ġis ol Ġs o Ġgen es Ġim p Ġs ingle Ġsim ilar Ġd id Ġg reat pl ant ro p c on ar m Ġtechn iqu Ġm g Ġt er Ġma jor K G Ġd ays o f in k Ġre le Ġde p Ġpos itive Ġv is ĠB AC Ġimpro ve U ND am ine lym ph Ġinf ection Ġwh ile Ġt em Ġcomp ar Ġse ver Ġf r om et c ed Ġprim ary Ġinc reas 5 0 Ġc y Ġde g RO UND ve re KG ROUND ĠBAC KGROUND Ġe l it es Ġsurg ery Ġpop ulation Ġocc ur Ġor gan Ġn ucle sy ch Ġph osph Ġev idence Ġspec ies v ing Ġhy dro di tions Ġdifferen ces s tr Ġre port Ġprotein s Ġp ers oc h Ġd ue Ġrel ated Ġre duced et a Ġm ark ron ic Ġs ome Ġe arly Ġcl ass Ġdiagn os Ġinf orm Ġl arge Ġpro v G F Ġs ensi E CT Ġb rain Ġsyn t is sion Ġres earch A R Ġcon ditions yp es 00 1 Ġrat s Ġar ter Ġ " Ġre ce C R u ce Ġv ol on al ec t Ġsec ond if e Ġsm all Ġpath w Ġh ospital Ġo l Ġr ati v es om ic Ġwe ek e u Ġeffec tive Ġpres ence en ing Ġt reated Ġen h c ent A S Ġ lymph ac tions Ġle ad ĠR es Ġ+ /- ver se Ġm at tr ic ) - he l Ġst ress Ġl ip Ġb ec Ġpo ly rom e Ġinclud ed t a age ment ĠA s Ġf em Ġa v ane ous Ġdec reased Ġab out Ġin iti Ġph ys Ġpro per Ġc urrent Ġpartic ip Ġob tained ial s is hed Ġ9 5 Ġsh ould g ative Ġen zym k in ĠC D Ġsurv ival an ti Ġcharacter is M P ations hip Ġpre vious ic k Ġpat tern ate ly Ġreveal ed Ġpr ac Ġc ult v iron ers t ul in Ġpro f A L th ough Ġl iver anc ed es ts med i Ġac ute Ġappro ach B J ran e rap y Ġsam ples Ġbet a ĠC on Ġdifferen ti Ġag ain O R ific ation ĠO ur Ġe le Ġres ist Ġco un Ġdevelop ed Ġab s Ġser um ep ti Ġfollow ing om y rel ated Ġmeasure d Ġv s el f ĠC om Ġstruct ure ĠR e Ġ1 5 Ġ2 00 o un es is Ġad v Ġpro l os s Ġinvestig ated Ġsign al Ġp e Ġconcentr ation BJ ECT enc es ens ity O S Ġad min Ġinj ur ro ph Ġp ain Ġthe y Ġf urther Ġdemonstr ated BJECT IV Ġf am Ġd er Ġp hen Ġpres s Ġ+ - Ġfunction al Ġch ronic Ġmolec ular and om ĠO BJECTIV ol es Ġrel ationship it her a x Ġconcentr ations yn amic Ġn an Ġevalu ated Ġmethod s Ġd ose Ġv al Ġagain st p e Ġqu ality Ġdes ign Ġin duced ici ent Ġoutc omes ly c ter m Ġs et Ġal pha Ġsur face 2 0 Ġst and Ġ ul Ġb inding Ġstud ied Ġdi ab Ġund erst tor y Ġsyn d m e s pec Ġm ater Ġv itro Ġg as ad e M S ic ity C s se qu m ine an n 1 1 Ġ est Ġvir us Ġ3 0 Ġes tim Ġcon duc Ġb one Ġf l Ġr ates Ġpo lym Ġpro duc Ġw ill Ġno vel A P Ġprov ide b eta tal ity Ġl es Ġb acter ell ular Ġf our Ġinform ation Ġn ec Ġhe p Ġcon trib p tion on ic Ġloc al Ġactiv ation a use Ġpro ced at us Ġinf lamm Ġplas ma ic ations Ġs us Ġch rom viron ment ul ations press ed Ġsubjec ts ĠP ro Ġp ur Ġp ul Ġne ur op ath Ġ1 4 Ġstr ateg Ġr andom ab l Ġ ur Ġsymptom s Ġan im I D Ġdeter mine ol ic othe rapy Ġelec tro Ġex t o le cop y ĠC O Ġreg ion Ġmulti ple Ġexper i ir c ĠU n l ine v ent Ġ > I C Ġvalu es in f is ion Ġmodel s Ġw ater Ġpar amet Ġanal ys ar c Ġproper ties Ġl ine Ġd om s ing Ġman agement Ġl ab Ġmor tality Ġrati o Ġl ife oc y Ġf ail Ġo s Ġcom mun Ġtrans crip ol ar t o Ġp sych Ġ2 4 ater al Ġ1 8 Ġvari ous Ġcar cin ol ution Ġ u R P Ġpro duction Ġsup port Ġexamin ed Ġdisc us 9 5 Ġl ung tain ing Ġreg ul Ġpress ure Ġrel ative Ġbe fore y ear cl usion Ġb ody Ġc le ul es Ġs u Ġd ys Ġ Q i at Ġmechan isms ocyt es ĠE x eth yl Ġdetermin ed Ġwhe ther ut ed Ġan g ĠA d a e 1 3 ici ency Ġform ation ĠA c eu tic Ġ1 3 is ts Ġsynd rome g r ĠA m Ġ ed ĠF urther Ġdis trib g ro Ġidentif y Ġo per at ures Ġg u Ġperform ance ons es Ġe qu Ġl oss Ġexpos ure Ġmed ical Ġre d al pha tic ally Ġassoci ation 1 5 d ependent Ġcol lec oc hem reas t tro s Ġse vere Ġsc re tom y u tr Ġp ub as is 1 4 ple ment Ġ1 6 Ġrec om Ġassess ed I S ur ation Ġr ange ograph ic em ia Ġelec tr g l w ent Ġex c Ġsam e I N Ġim aging I n w ard Ġm ass Ġne gative ac tive A D Ġe ither Ġmechan ism ĠI L Ġresp onses ĠH ere Ġwe ight Ġch ange Ġsever al Ġse x oc ial Ġcomp ound at in y r iv o Ġinvol ved in c Ġgreat er Ġmus cle Ġgl uc Ġshow n iv ing Ġconf ir en sion Ġh is Ġdise ases o ly Ġdi rect Ġresist ance y si Ġh ist olog ic im in Ġdifferen ce l ing 1 8 Ġintr a Ġav ail Ġ ve Ġkn own Ġmemb rane Ġre pres Ġde ath C C us t pa ir Ġdet ected Ġpro b Ġanaly zed N T Ġcomp lic g n Ġstr ong Ġcomp on Ġph ase Ġre duction erg y Ġl ike anc y ĠP ati Ġcar b l or Ġcharacteris tics or ph id es Ġf low ent er Ġto x ud e d s Ġs ize Ġevalu ate is on Ġen vironment Ġunderst and ogen esis Ġv ivo Ġv ia p ose Ġ X anc es Ġbehavi or ĠI I spec ific is ed et es Ġinjur y E R Ġweek s or ding Ġpar t Ġmic ros Ġpos sible Ġgener al Ġres id a z te gr hib ition Ġpre val istr ation s c Ġac h Ġs elf Ġhe art Ġdet ection Ġpro ble Ġan y ous e Ġv ac Ġ . 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hibit Ġextr ac Ġh ow ib le Ġn et Ġmor ph el ine Ġhigh ly or der ĠO n ĠAl though Ġ1 1 entr ic Ġbet ter iat ric Ġm ac Ġc ere ul f Ġisol ated Ġd ay Ġimpro ved Ġat ten l er Ġevalu ation is tic Ġ2 5 Ġimmun e ĠE n y gen Ġcons ist Ġcontr ast n er Ġmet ast Ġinc idence er ic Ġconsid ered % ), ĠC a ot ype Ġp epti ĠPati ents f ac Ġin hibition Ġf at ĠN o Ġfam ily is ing ter ior el s Ġ1 7 am p Ġst ate a ke Ġass ay Ġ unc Ġim pl ab il g ra Ġbe ing Ġavail able Ġapp ear ord ers u k Ġl iter Ġrequi red C I Ġt rain ro w Ġsensi tivity Ġcaus ed Ġexperim ental Ġresul t ver s Ġcomple te Ġpathw ay Ġval id Ġm ale u ally Ġch all v ant . , Ġar tic e y Ġdiab etes ol s Ġdis t Ġprol if Ġcomplic ations Ġdec rease ĠH IV Ġassess ment ut ure Ġindividual s Ġfollow ed Ġph arm k g er m a i ator s Ġin tegr Ġh owever Ġind ex Ġad d Ġenzym e Ġles ions Ġt ub Ġsur ve Ġparticip ants ve ment an tit Ġem b Ġfe atures Ġcorrel ation Ġcardi ac Ġk in Ġinflu ence ro b c hem Ġv ery ow led Ġpreval ence ial ly y ro Ġinter vention Ġt ypes res pon Ġor der Ġrap id Ġle ft c t h ort ab ly Ġfrequ ency Ġs ite ar b c ence g o Ġpro st Ġsup er Ġtum ors it u C D Ġre pl Ġul tr Ġindic ate Ġbl ock Ġt ested Ġfoc us Ġphys ical o red Ġf il Ġ Z Ġh om Ġm RNA en z Ġv ers o ung Ġover all r ation ĠA fter i ent Ġcombin ation Ġrece ived l ast Ġrepres ent Ġprog n Ġdrug s Ġdistrib ution Ġrec ord owled ge Ġeff icacy iz ing ub le n ormal Ġhe ter Ġanalys es Ġbi om Ġep it % ). m ore our s Ġprevious ly Ġca use Ġat t eng th Ġcarcin oma Ġab ility Ġre duc Ġsam ple Ġthe m le x S A 00 0 Ġdis orders on es Ġliter ature ĠM ore Ġinter action Ġ er Ġsynt hesis i o us tr Ġfail ure Ġos te Ġbec ause Ġwhe re plant ation Ġpre c Ġs ites Ġsc ore ot ox Ġen ergy Ġsh ort and s Ġu til Ġcont ent Ġs kin Ġem erg ten sion Ġinter val ĠR ec Ġc ri Ġd os Ġd ynamic Ġsignal ing T P ur n om p Ġgluc ose Ġc ur Ġadmin istration Ġs ocial in ary Ġl ight ĠS c Ġdescrib ed 3 0 ar tic ĠM ed Ġa min Ġpl ace uc tion Ġd am Ġnet work Ġtran si urren ce Ġstim ul Ġsub st ra g Ġprog ram he st 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Ġf oster Ġhall mark ĠH ome ER D Ġser ous it real Ġspl itting st yrene ĠReg ression Ġun met S pecific ensi ti Ġimplant able ore tical ĠG h Ġpass ed ĠV E Ġmy x Ġbronch i ifferenti ation di phenyl ap le ip olar ĠHT LV ĠPort ug Ġs ister amin ated ĠK RAS Ġdest abil on v ĠE E Ġtub ule AM L ĠWe ight Ġc ogn ĠNL RP ĠB SA Ġsup ramolecular opid ogrel ib li gen ome Ġb ag Ġpar ity per t Ġsub c Ġch ip Ġeosin ophil Ġun in C AT Ġeukary otes ad ec r ater duc tase Ġalcoh ols a ec Ġre imb T EM ĠRN ase amin idase RET ATION ke phal ĠB F Ġhelp ing ĠRh od Ġan te ĠM CA Ġpoly acrylamide Ġh s Ġl umin Ġdep olar S N Ġtrans parent Ġlack ed ĠGl ut ĠVi etnam tetra hydro ĠG G Ġdi ethyl ĠH emat ĠLip id un ch ES I Ġfacil itation T MS Ġc anc ĠB CL Ġves icular Ġbi ophysical ick ed Ġrich ness respon ders Ġsingle t Ġelectroph ysi Ġsound s ĠG astric ah aran Ġk Hz Ġread ers Ġsp anning ide ment Ġsoph istic Ġnucle ation operative ly ogene ity k b ole ic ĠB PD Ġpi per ĠSt atus Ġk ill ĠR heum L N Ġcomp ressive Ġamelior ated Ġco 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