SEC Filing Document

Company: Synergy CHC Corp.
Ticker: SNYR
CIK: 1562733
Filing Type: S-1MEF
Document Type: EX-5.1
Date Filed: 2024-10-22
Accession Number: 0001213900-24-089733
Exchange: Nasdaq
SIC Code: 2833
SIC Description: Medicinal Chemicals & Botanical Products
URL: https://www.sec.gov/Archives/edgar/data/1562733/000121390024089733/ea021815801ex5-1_synergy.htm

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Exhibit 5.1

NELSON MULLINS
RILEY & SCARBOROUGH LLP
ATTORNEYS AND COUNSELORS AT LAW

301 Hillsborough Street, Suite 1400
Raleigh,
nelsonmullins.com

October 22, 2024

Synergy CHC Corp.

865 Spring Street

Westbrook, Maine 04092

Re: Registration Statement on Form S-1MEF

Ladies and Gentlemen:

We have examined the Registration Statement on
Form S-1 (the “Registration Statement”) of Synergy CHC Corp., a Nevada corporation (the “Company”),
filed with the Securities and Exchange Commission pursuant to Rule 462(b) under the Securities Act of 1933, as amended (the “Securities
Act”), in connection with the offering by the Company of: (a) an aggregate of up to 172,500 shares (the “Shares”)
of the Company’s common stock, par value $0.00001 per share (the “Common Stock”); (b) the representative’s
warrants that will be issued by the Company to the representative of the underwriters of the offering (the “Representative’s
Warrants”); and (c) a number of shares of Common Stock equal to 9% of the Shares sold in the offering, issuable upon exercise
of the Representative’s Warrants (the “Representative’s Warrant Shares”). The Registration Statement incorporates
by reference the Registration Statement on Form S-1, as amended (File No. 333-280556) (the “Prior Registration Statement”),
including the prospectus which forms a part of the Prior Registration Statement.

In arriving at the opinions expressed below, we
have examined the Prior Registration Statement, originals, or copies certified or otherwise identified to our satisfaction as being true
and complete copies of the originals, of specimen common stock certificates, and such other documents, corporate records, certificates
of officers of the Company and of public officials and other instruments as we have deemed necessary or advisable to enable us to render
the opinions set forth below. In our examination, we have assumed without independent investigation the genuineness of all signatures,
the legal capacity and competency of all natural persons, the authenticity of all documents submitted to us as originals and the conformity
to original documents of all documents submitted to us as copies.

Based upon the foregoing, and subject to the assumptions,
exceptions, qualifications and limitations set forth herein, we are of the opinion that: (i) the Shares, when issued against payment therefor
as set forth in the Registration Statement, will be validly issued, fully paid and non-assessable; (ii) the Representative’s Warrant
Shares, when issued upon exercise of the Representative’s Warrants, will be validly issued, fully paid and non-assessable; and (iii)
the Representative’s Warrants, when issued as set forth in the Registration Statement, will be legal, valid and binding obligations
of the Company, enforceable against the Company in accordance with their terms.

California | Colorado | District
of Columbia | Florida | Georgia | Illinois | Maryland | Massachusetts | Minnesota

New York | North Carolina | Ohio
| Pennsylvania | South Carolina | Tennessee | Texas | Virginia | West Virginia

Synergy CHC Corp.

October 22, 2024

Page 2

The opinions expressed above are subject to the
following additional exceptions, qualifications, limitations and assumptions:

A. Our opinion expressed herein is limited to the federal laws of the United States, the laws of the State of New York and Chapter
78 of the Nevada Revised Statutes. The opinions expressed herein are based upon the federal laws of the United States, the laws of the
State of New York and Chapter 78 of the Nevada Revised Statutes in effect on the date hereof and as of the effective date of the Registration
Statement. We assume no obligation to revise or supplement this opinion in the event of future changes in such laws or the interpretations
thereof or such facts.

B. The opinion in clause (iii) above is
subject to (a) the effect of any bankruptcy, insolvency, reorganization, moratorium, arrangement or similar laws affecting the
rights and remedies of creditors’ generally, including without limitation the effect of statutory or other laws regarding
fraudulent transfers or preferential transfers, and (b) general principles of equity, including without limitation concepts of
materiality, reasonableness, good faith and fair dealing and the possible unavailability of specific performance, liquidated
damages, injunctive relief or other equitable remedies regardless of whether enforceability is considered in a proceeding in equity
or at law.

We consent to the filing of this opinion as an
exhibit to the Registration Statement, and we further consent to the use of our name under the caption “Legal Matters” in
the Registration Statement and the prospectus that forms a part thereof. In giving these consents, we do not thereby admit that we are
within the category of persons whose consent is required under Section 7 of the Securities Act or the Rules and Regulations of the Commission.

Very truly yours,

/s/ Nelson Mullins Riley & Scarborough LLP