SEC Filing Document

Company: Synergy CHC Corp.
Ticker: SNYR
CIK: 1562733
Filing Type: S-1
Document Type: EX-5.1
Date Filed: 2025-08-15
Accession Number: 0001213900-25-077458
Exchange: Nasdaq
SIC Code: 2833
SIC Description: Medicinal Chemicals & Botanical Products
URL: https://www.sec.gov/Archives/edgar/data/1562733/000121390025077458/ea024071103ex5-1_synergy.htm

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Exhibit 5.1

NELSON MULLINS RILEY & SCARBOROUGH LLP
ATTORNEYS AND COUNSELORS AT LAW

301 Hillsborough Street, Suite 1400
Raleigh, NC 27603
nelsonmullins.com

August 15, 2025

Synergy CHC Corp.

865 Spring Street

Westbrook, Maine 04092

Re: Registration Statement
on Form S-1

Ladies and Gentlemen:

We have examined the Registration
Statement on Form S-1, as amended (the “Registration Statement”), of Synergy CHC Corp., a Nevada corporation (the “Company”),
filed pursuant to the Securities Act of 1933, as amended (the “Securities Act”), in connection with the offering by
the Company of: (a) up to an aggregate of 1,466,836 shares (the “Shares”) of the Company’s common stock, par
value $0.00001 per share (the “Common Stock”), including up to 191,326 shares that may be sold pursuant to the underwriters’
over-allotment option; (b) the representative’s warrants that will be issued by the Company to the representative of the underwriters
of the offering (the “Underwriter Warrants”); and (c) up to 38,265 shares of Common Stock issuable upon exercise of
the Underwriter Warrants (the “Underwriter Warrant Shares”).

In arriving at the opinions
expressed below, we have examined originals, or copies certified or otherwise identified to our satisfaction as being true and complete
copies of the originals, of specimen common stock certificates, and such other documents, corporate records, certificates of officers
of the Company and of public officials and other instruments as we have deemed necessary or advisable to enable us to render the opinions
set forth below. In our examination, we have assumed without independent investigation the genuineness of all signatures, the legal capacity
and competency of all natural persons, the authenticity of all documents submitted to us as originals and the conformity to original documents
of all documents submitted to us as copies.

Based upon the foregoing,
and subject to the assumptions, exceptions, qualifications and limitations set forth herein, we are of the opinion that: (i) the Shares,
when issued against payment therefor as set forth in the Registration Statement, will be validly issued, fully paid and non-assessable;
(ii) the Underwriter Warrant Shares, when issued upon exercise of the Underwriter Warrants, will be validly issued, fully paid and non-assessable;
and (iii) the Underwriter Warrants, when issued as set forth in the Registration Statement, will be legal, valid and binding obligations
of the Company, enforceable against the Company in accordance with their terms.

California
| Colorado | District of Columbia | Florida | Georgia | Illinois | Maryland | Massachusetts | Minnesota

New York
| North Carolina | Ohio | Pennsylvania | South Carolina | Tennessee | Texas | Virginia | West Virginia

Synergy CHC Corp.

August 15, 2025

Page 2

The opinions expressed above
are subject to the following additional exceptions, qualifications, limitations and assumptions:

A. Our opinion expressed herein
is limited to the federal laws of the United States, the laws of the State of New York and Chapter 78 of the Nevada Revised Statutes.
The opinions expressed herein are based upon the federal laws of the United States, the laws of the State of New York and Chapter 78 of
the Nevada Revised Statutes in effect on the date hereof and as of the effective date of the Registration Statement. We assume no obligation
to revise or supplement this opinion in the event of future changes in such laws or the interpretations thereof or such facts.

B. The opinion in clause (iii)
above is subject to (a) the effect of any bankruptcy, insolvency, reorganization, moratorium, arrangement or similar laws affecting the
rights and remedies of creditors’ generally, including without limitation the effect of statutory or other laws regarding fraudulent
transfers or preferential transfers, and (b) general principles of equity, including without limitation concepts of materiality, reasonableness,
good faith and fair dealing and the possible unavailability of specific performance, liquidated damages, injunctive relief or other equitable
remedies regardless of whether enforceability is considered in a proceeding in equity or at law.

We consent to the filing of
this opinion as an exhibit to the Registration Statement, and we further consent to the use of our name under the caption “Legal
Matters” in the Registration Statement and the prospectus that forms a part thereof. In giving these consents, we do not thereby
admit that we are within the category of persons whose consent is required under Section 7 of the Securities Act or the Rules and Regulations
of the Commission.

Very truly yours,

/s/ Nelson Mullins Riley & Scarborough LLP