8) An obstetrical patient has had previous pregnancies. Her first baby was healthy, the second was jaundiced at birth and required an exchange transfusion, while the third was stillborn. Which of the following is the most likely cause? A) ABO incompatibility B) Immune Deficiency Disease C) Congenital Spherocytic Anemia D) Rh Incompatibility D 9) With regard to the inheritance, most blood groups systems are: A) Sex-linked dominant B) Sex-linked recessive C) Autosomal recessive D) Autosomal codominant D 10) The optimum storage temperature of Cryoprecipitated AHF is: A) 22°C B) 4°C C) -12°C D) -20°C D 11) The optimum storage temperature for Platelets is: A) 22°C B) 4°C C) -12°C D) -20°C A 12) Fever and chills are symptoms of which of the following transfusion reactions? A) Citrate toxicity B) Circulatory overload C) Allergic D) Febrile D 13) Hyptotension, nausea, flushing, and chill are symptoms of which of the following transfusion reactions? A) Allergic B) Circulatory overload C) Hemolytic D) Anaphylactic C 14) Quality control tests must be performed daily on: A) Reagent red blood cells B) Oral thermometers C) Banked whole blood D) Centrifuge timers A 15) Criteria determining Rh immune globulin eligibility include: A) mother is Rh-positive B)infant is Rh-negative C)mother has not been previously immunized to the d antigen D) infant has a positive direct antiglobulin test C 16) Which of the following constitute permanent rejection status of a donor: D
12) A urinalysis performed on a 27-year old woman yields the following results. Sp. Gravity 1.008 microscopic PH 5.0 WBC/HPF 20-30 Protein 2+ RBC/HPF 30-55 Glucose negative Ketones negative Hyaline 5-7 Bilirubin negative Red Cell 2-3 Blood 3+ Coarse granular 2-3 Nitrite negative Waxy 1-3 Leukocytes positive Uric acid crystals- Moderate Urobilinogen 0.1Eu/dl The above data are consistent with Nephritic syndrome Gout Biliary obstruction Chronic renal disease D. 13) A 52 year old man has urine glucose measurements performed as part of a three (3) hour glucose tolerance test. The test results are as follows: Time Serum Glucose Urine Glucose Fasting 82 mg/dl negative ½ hour negative 1 hour 190mg/dl negative 2 hour 115mg/dl 1+ 3 hour 95mg/dl trace The best explanation for these findings is that the: level must exceed the threshold level before glucose is filtered by the renal glomeruli Serum level must exceed the threshold level before reabsorption of glucose is exceeded Tested patient probably has renal glucosuria Tested patient probably has diabetes mellitus. B. 14) How many grams of sulfasalicylic acid (MW=254) are required to prepare 1L of a 3% (WV) solution 3 B.
Ketones will increase due to bacterial and cellular metabolism 13) The following results were obtained on a 25 year old female Color – Amber Appearance – cloudy Specific Gravity – 1.015 pH – 5.0 Protein – 1+ Glucose – negative – small Bacteria – many WBC Casts – few WBC/HPF – 30-40 Results are most compatible with? Glomerulonephritis Calculus Vaginitis Pyelonephritis D 14) The middle of a data set is statistically known as the: Mean Median Mode Standard Deviation B 15) In automated methods utilizing a biochromatic analyzer, dual wavelengths are employed to: A) minimize the effects of interference B) improve precision C) increase throughput D) monitor temperature changes A 16) A urine screening test for porphobilinogen is positive. The MOST likely disease state is: A) lead poisoning B)porphyria cutanea tarda C.)acute porphyria attack C
D) erythrocytic protophyria 17) Magnesium carbonate is added in an iron binding capacity determination in order to: A) allow color to develop B) precipitate protein C) bind with hemoglobin iron D) remove excess unbound iron D 18) A condition in which erythrocyte protoporphyrin is increased is: A) acute intermittent porphyria B) iron deficiency anemia C) porphyria cutanea tarda D) acute porphyric attack B 19) This pattern is consistent with: Patient values Ref. Values Total protein 6.1 g/dL 6.0-8.0 g/dL Albumin 2.3 g/dL 3.6-5.2 g/dL Alpha-1 0.2 g/dL 0.1-0.4 g/dL Alpha-2 0.5 g/dL 0.4-1.0 g/dL Beta 1.2 g/dL 0.5-1.2 g/dL Gamma 1.9 g/dL 0.6-1.6 g/dL A) cirrhosis B) acute inflammation C) polyclonal gammopathy (e.g. chronic inflammation) D) alpha-1 antitrypsin deficient, severe emphysema A 20) A patient with glomerulonephritis would present the following serum results: A) creatinine decreased B) calcium increased C) phosphorous decreased D) BUN increased D 21) Absorption of vitamin B12 requires the presence of: A) intrinsic factor B) gastrin C) secretin D) acid A 22) A 68 year old man arrives in the emergency room with a glucose level of 722 mg/dL and serum acetone of a 4+ undiluted. An arterial blood gas from this patient is likely to indicate which of the following? Low pH High pH Low pO2 High pO2 A 23) What battery of tests is most useful in evaluating an anion gap of 22mEq/L? Ca++, Mg++, PO4- and pH BUN, creatinine, salicylate, and methanol AST, ALT, LD and amylase Glucose, CK, myoglobin, and cryoglobulin B
Pelger-Huet anomaly Chediak-Higashi syndrome Gaucher’s disease 7) The most appropriate screening test for detecting cells with predominant hemoglobin F is: Osmotic fragility Dithionite solubility Kleihauer-Betke test Heat instability test C 8) Coagulation factors affected by coumarin drugs are: VIII, IX and X I, II, V and VII II, VII, IX and X II, V and VII C 9) is associated with Alder-Reilly inclusions? membrane defect of lysosomes Döhle bodies and giant platelets two-lobed neutrophils mucopolysaccharidosis D 10) The most appropriate screening test for hereditary spherocytosis is: osmotic fragility sucrose hemolysis heat instability test Kleihauer-Betke test A 11) The most appropriate screening test for paroxysmal nocturnal hemoglobinuria is: heat stability test sucrose hemolysis osmotic fragility dithionite solubility B 12) The characteristic morphologic feature in multiple myeloma is: cytotoxic T cells rouleaux formation spherocytosis macrocytosis B 13) A morphologic feature common in hemoglobin C disease is: macrocytosis spherocytosis rouleaux formation target cells D 14) Hematology standards include: stabilized red blood cell suspension latex particles stabilized avian red blood cells certified cyanmethemoglobin solution D