Table 1. Overview of the substances demonstrating physicochemical properties related to high migration and bioavailability potential and included in both the FACET tool and the Community Rolling Action Plan (CoRAP) list (consulted on June 15, 2016). CMR: Carcinogenic, Mutagenic or Reprotoxic substances; PBT: Persistent, Bioaccumulative and Toxic substances; RCR: Risk Characterisation Ratio; vPvB: very Persistent and very Bioaccumulative substances. Chemical name CAS number Reason of concern Evaluation status 3,5-Dimethylpyrazole 67-51-6 High RCR Reprotoxic Not started Chloromethane 74-87-3 CMR Potential endocrine disruptor High RCR Information requested Dichloro(dimethyl)silane 75-78-5 High (aggregated) tonnage Suspected PBT/vPvB Concluded 3,5,5-Trimethylcyclohex-2-enone 78-59-1 CMR Exposure of workers High (aggregated) tonnage Wide dispersive use Information requested Bis(α,α-dimethylbenzyl) peroxide 80-43-3 Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage High RCR Suspected PBT/vPvB Wide dispersive use Ongoing p-(1,1-Dimethylpropyl)phenol 80-46-6 Consumer use Potential endocrine disruptor Wide dispersive use Information requested 2-(4-Tert-butylbenzyl)propionaldehyde 80-54-6 CMR Wide dispersive use Consumer use Information requested 85-60-9 Suspected Reprotoxic Potential endocrine disruptor Suspected PBT/vPvB Wide dispersive use Exposure of environment Consumer use Exposure of workers Not started Naphthalene 91-20-3 Exposure of workers High (aggregated) tonnage High RCR exposure/risk based concern Ongoing Benzotriazole 95-14-7 Potential endocrine disruptor Exposure of environment Ongoing o-Xylene 95-47-6 Consumer use Cumulative exposure High (aggregated) tonnage Ongoing
High RCR Suspected CMR Suspected Sensitiser Wide dispersive use Butanone oxime 96-29-7 Consumer use Cumulative exposure CMR High RCR Sensitiser Wide dispersive use Concluded 2,4-Di-tert-butylphenol 96-76-4 Consumer use Potential endocrine disruptor Suspected CMR Wide dispersive use Not started Furfuryl alcohol 98-00-0 Consumer use CMR Exposure of environment Exposure of workers High (aggregated) tonnage Wide dispersive use Information requested 4-Tert-butylpyrocatechol 98-29-3 Suspected Mutagenic Sensitiser Potential endocrine disruptor Suspected PBT/vPvB Exposure of environment Exposure of workers Not started Triphenyl phosphite 101-02-0 Consumer use High (aggregated) tonnage Potential endocrine disruptor Sensitiser Suspected CMR Wide dispersive use Information requested 2-Ethylhexyl acetate 103-09-3 Consumer use Suspected CMR Wide dispersive use Conclusion under preparation 4-Methylanisole 104-93-8 Consumer use CMR High RCR Wide dispersive use Concluded 2,2'-Methyliminodiethanol 105-59-9 High (aggregated) tonnage High RCR Suspected CMR Wide dispersive use Ongoing p-Xylene 106-42-3 Consumer use Cumulative exposure High (aggregated) tonnage High RCR Suspected CMR Suspected Sensitiser Wide dispersive use Ongoing m-Xylene 108-38-3 Consumer use Cumulative exposure High (aggregated) tonnage High RCR Ongoing
3-Methylbutan-1-ol 123-51-3 Consumer use Exposure of workers Suspected Carcinogenic Suspected Reprotoxic Suspected Sensitiser Not started Acetone 127-06-0 Exposure of environment Exposure of workers High RCR Suspected Carcinogenic Suspected Mutagenic Suspected Sensitiser Wide dispersive use Ongoing Imidazole 288-32-4 CMR Wide dispersive use High (aggregated) tonnage Information requested 1,2,4-Triazole 288-88-0 Exposure of environment High (aggregated) tonnage Other exposure/risk based concern Other hazard based concern Suspected CMR Wide dispersive use Ongoing Diuron 330-54-1 Potential endocrine disruptor Wide dispersive use Other exposure/risk based concern Ongoing Tert-butyl perbenzoate 614-45-9 Consumer use Sensitiser Wide dispersive use Information requested Dimethoxydimethylsilane 1112-39-6 Reprotoxic Other hazard based concern Exposure of workers Not started Dimethyl glutarate 1119-40-0 Consumer use High (aggregated) tonnage Potential endocrine disruptor Wide dispersive use Concluded Trimethoxy(methyl)silane 1185-55-3 Sensitiser Wide dispersive use Consumer use High (aggregated) tonnage Ongoing Tert-butyl methyl ether 1634-04-4 Potential endocrine disruptor Wide dispersive use High (aggregated) tonnage Ongoing 2,3-Epoxypropyl o-tolyl ether 2210-79-9 Mutagenic Ongoing 7-Oxabicyclo[4.1.0]hept-3-ylmethyl [4.1.0]heptane-3-carboxylate 2386-87-0 Suspected CMR Sensitiser Exposure of workers High RCR Information requested (TGIC) 2451-62-9 Consumer use CMR Exposure of environment Conclusion under preparation
Exposure of workers Suspected PBT/vPvB Wide dispersive use 3,5,5-Trimethylhexanoic acid 3302-10-1 Suspected Reprotoxic Exposure of workers Not started N-Butylbenzenesulphonamide 3622-84-2 Suspected PBT/vPvB Exposure of workers High (aggregated) tonnage Not started 4719-04-4 Exposure of workers High (aggregated) tonnage High RCR hazard based concern Not started 5026-74-4 Consumer use Exposure of workers Suspected Mutagenic Suspected Sensitiser Not started Citral 5392-40-5 Consumer use Exposure of workers High (aggregated) tonnage Sensitiser Wide dispersive use Conclusion under preparation Di-tert-butyl diperoxide 6731-36-8 Suspected PBT/vPvB Information requested 13393-93-6 Suspected PBT/vPvB Wide dispersive use Exposure of environment High RCR Not started acrylate 17527-29-6 Exposure of environment Other hazard based concern Potential endocrine disruptor Suspected PBT/vPvB Wide dispersive use Ongoing Tetrapropylenebenzene 25265-78-5 High (aggregated) tonnage Suspected CMR Suspected PBT/vPvB Ongoing Acrylic acid, monoester with 25584-83-2 Suspected Carcinogenic Suspected Mutagenic Suspected Sensitiser Wide dispersive use Exposure of workers High RCR High (aggregated) tonnage exposure/risk based concern Not started Oxydipropyl dibenzoate 27138-31-4 Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage High RCR Suspected Reprotoxic Wide dispersive use Not started Methacrylic acid, monoester with propane-1,2-diol 27813-02-1 Suspected CMR Sensitiser Wide dispersive use Consumer use Ongoing