Ornamentals 0.1 L/100 L water 1# Airblast 12 12 Low/high pressure handwand 1 1 Backpack sprayer 0.1** 0.1 Potato 1 0.5 Ground boom 30 15 2–3 applications in sufficient water to ensure thorough coverage Stone fruit 75 mL/100 L water 0.75 Airblast 30 22.5 Four applications using dilute or concentrate spray at 2–week interval Turfgrass 0.1 L/100 m2 5 Ground boom 20 100 Applied in 5–10 L water/100 m2. Applied at first sign of disease. Repeated at 2–4 week intervals Low/High pressure handwand 1 5 Backpack sprayer 0.5** 2.5 Garlic 0.01 L/kg - Clove treatment - 5 (treatment plant) Pre-plant clove treatment 3 (on farm) *OCS default unless otherwise stated; #Based on 2000 L/ha spray volume; ‡Dilute one part of product with equal volume of water (as per label); §Application method considered similar to ground boom; ^Assumed 100 tonnes of seeds treated per day for treatment plant and 60 tonnes of seeds treated per day for on-farm system. **Information provided by the APVMA
Exposure tables represent the total exposure to the active constituent. Estimates are for workers wearing long pants and long sleeved shirt (single layer of clothing). Exposure values are based on worker bodyweight of 70 kg bw, 3% dermal absorption factor, and a 100% default inhalational absorption factor. Table —Estimates of systemic exposure to procymidone in the 500 g/L products (mg/kg bw/d) Estimates Gloves Mixer/loader dermal Applicator dermal Mixer/ loader Inhalation Applicator Inhalation Total exposure Aerial application – Mixing/loading only Estimate 1: All liquids, open mixing and loading (S3) 900 kg ac/d Y 0.0195 0.0340 0.0536 Y# 0.0195 0.0034 0.0229 Aerial application – Application only Estimate 2: Aerial-fixed wing/enclosed cockpit/liquid application (S7) 900 kg ac/d No specific PPE - 0.0043 - 0.0019 0.0062 Ground boom application Estimate 3: All liquids, open mixing and loading & ground boom application, open cab (S3, S13) 100 kg ac/d N 0.2699 0.0013 0.0038 0.0023 0.2773 Y 0.0022 0.0013 0.0038 0.0023 0.0096 Airblast application Estimate 4: All liquids, open mixing and loading & airblast application, open cab (S3, S11) 22.5 kg ac/d N 0.0607 0.0077 0.0009 0.0032 0.0725 Y 0.0005 0.0051 0.0009 0.0032 0.0097 Low pressure handwand application Estimate 5: All liquids open mixing and loading & low pressure handwand application (S3, S18) 5 kg ac/d Y 0.0001 0.0334 0.0002 0.1480 0.1817 Y^ 0.0001 0.0080 0.0002 0.0148 0.0231
1400 High Full Harvesting (hand) 580 Low or high Full or min Pruning (hand), scouting, training 230 Low Min Transplanting 100 High Full Bird control, orchard maintenance, propping, weeding (hand) Turfgrass 5 6700 Low Full Maintenance, harvesting (slab), transplanting/planting 3700 Low Full Maintenance 2500 Low Full Maintenance (greens only) Table —Post-application exposure estimates after use of 500 g/L procymidone products Situation Maximum overall application rate (kg ac/ha) Transfer Co-efficient (cm2/h) Activity Days after treatment Exposure (mg/kg bw/d) Canola 0.5 1100 Scouting 0 0.005 Navy beans, Faba beans, Lentils 0.75 1900 Irrigation (hand) 0 0.012 1100 Scouting 0 0.007 Grapes (incl. wine grapes) 0.75 10100 Tying/training, harvesting (hand), leaf pulling 0 0.065 5 0.038 6 0.035 1900 Irrigation (hand) 0 0.012 640 Pruning (hand), weeding (hand), scouting, propagating, bird control, trellis repair 0 0.004 230 Transplanting 0 0.001
Onions 2 4200 Weeding (hand) 0 0.072 6 0.038 7 0.034 1900 Irrigation (hand) 0 0.033 1400 Scouting 0 0.024 Ornamentals 1 1900 Irrigation (hand) 0 0.016 230 Container moving, grafting, harvesting (hand), pinching, propagating, pruning (hand), scouting, transplanting, tying/training, weeding (hand) 0 0.002 Potato 0.5 1900 Irrigation (hand) 0 0.008 210 Scouting 0 0.001 70 Weeding (hand) 0 0.000 Stone fruit 0.75 3600 Thinning fruit 0 0.023 1400 Harvesting (hand) 0 0.009 580 Pruning (hand), scouting, training 0 0.004 230 Transplanting 0 0.001 100 Bird control, orchard maintenance, propping, weeding (hand) 0 0.001 Turfgrass 5 6700 Maintenance, harvesting (slab), transplanting/planting 0 0.011 3700 Maintenance 0 0.006 2500 Maintenance (greens only) 0 0.004
Y^ 23029 311 13230 169 108 Users conducting open mixing/loading and low pressure handwand application with PPE comprising of a second layer of clothing, gloves and a half facepiece respirator for applicators High pressure handwand application Estimate 6: All liquids open mixing and loading & high pressure handwand application (S3, S19) 5 kg ac/d N 185 295 13230 201 72 Users conducting mixing/loading and high pressure hand wand application with PPE comprising of elbow-length chemical resistant gloves Y 23029 827 13230 201 159 Users conducting mixing/loading and high pressure hand wand application with PPE comprising of elbow-length chemical resistant gloves Equipment carried on the back of the user Estimate 7: All liquids open mixing and loading & backpack application (S3,S20) 2.5 kg ac/d Y‡ 31738 6 66150 241 22 Users conducting open mixing/loading and backpack application with maximum PPE available Estimate 8: All liquids open mixing and loading & backpack application (S3,S20) 0.1 kg ac/d Y 287857 28 165374 602 108 Users conducting open mixing/loading and backpack application with PPE comprising of of elbow-length chemical resistant gloves for applicators
Ornamentals 1 1900 Irrigation (hand) 0 210 230 Container moving, grafting, harvesting (hand), pinching, propagating, pruning (hand), scouting, transplanting, tying/training, weeding (hand) 0 1800 Potato 0.5 1900 Irrigation (hand) 0 430 210 Scouting 0 3900 70 Weeding (hand) 0 12000 Stone fruit 0.75 3600 Thinning fruit 0 150 1400 Harvesting (hand) 0 390 580 Pruning (hand), scouting, training 0 940 230 Transplanting 0 2400 100 Bird control, orchard maintenance, propping, weeding (hand) 0 5400 Turfgrass 5 6700 Maintenance, harvesting (slab), transplanting/planting 0 300 3700 Maintenance 0 550 2500 Maintenance (greens only) 0 820 Acceptable MOEs (MOE ≥ 100) were achieved for situation/crops and respective post-application activities on the following days after treatment (Table 21).
Table —Summary of days after treatment for post-application activities (500 g/L procymidone products) Situation Activity Days after treatment Canola Scouting 0 Navy beans, Faba beans, Lentils Irrigation (hand) Scouting Grapes (incl. wine grapes) Tying/training, harvesting (hand), leaf pulling 6 Irrigation (hand) 0 Pruning (hand), weeding (hand), scouting, propagating, bird control, trellis repair Transplanting Onions Weeding (hand) 7 Irrigation (hand) 0 Scouting Ornamentals Irrigation (hand) 0 Container moving, grafting, harvesting (hand), pinching, propagating, pruning (hand), scouting, transplanting, tying/training, weeding (hand) Potato Irrigation (hand) 0 Scouting Weeding (hand) Stone fruit Thinning fruit 0 Harvesting (hand) Pruning (hand), scouting, training Transplanting Bird control, orchard maintenance, propping, weeding (hand)
Time d Day h Hour min Minute wk Week yr Year yo Year old Weight bw Bodyweight g Gram kg Kilogram μg Microgram mg Milligram ng Nanogram pg Picogram Length cm Centimetre m Metre μm Micrometre mm Millimetre nm Nanometre Dosing i.p. Intraperitoneal mg/kg bw/d Milligram/kilogram bodyweight/day s.c. Subcutaneous Frequency
APPENDIX III: ORGANS FOR WEIGHT DETERMINATION AND HISTOPATHOLOGICAL EXAMINATION Organs weighed Tissues examined Adrenals Brain Gonads Heart Kidneys Liver Spleen Thyroid (w/parathyroid) Adrenals Aorta Blood smear Bone Bone marrow Brain (3 levels) Cecum Colon Duodenum Epididymides Eyes Eyes (optic nerve) Gall bladder Harderian glands Head - 3 sections (nasal cavity, para-nasal sinus, tongue, oral cavity, inner-ear) Heart Ileum Jejunum Kidneys Lacrimal gland Liver Lungs Lymph nodes Mammary gland Muscle (smooth) Muscle (skeletal) Nerve (peripheral) Oesophagus Ovaries Pancreas Pituitary Prostate Rectum Salivary gland Seminal vesicle Skin Spinal cord (cervical thoracic, lumbar) Spleen Sternum Stomach Testes Thymus Thyroid (w/parathyroid) Trachea Urinary bladder Uterus Vagina Zymbal's gland Gross lesions