and control – the nervous system – delivery guide systems reflexes/reaction times B3.2 Coordination and control – the endocrine system 8.0/5.0 Organism level systems – delivery guide PAG B6: Physiology, responses respiration - Investigation of the effects of phototropism using seedlings B3.3 Maintaining internal environments 9.0/4.0 Organism level systems – delivery guide PAG B8: Transport in and out of cells - Demonstration of the different water potentials on different cells Total for topic 3 = 24.0 / 12.0 hours Topic B4: Community level systems B4.1 Ecosystems 9.0/5.0 Community level systems – delivery guide PAG B1: - Examination of the roots of a leguminous plant PAG B3: Sampling techniques - Investigation of the holly leaf miner or the horse-chestnut leaf miner (Cameraria ohridella) PAG B3: Sampling techniques - Identification of the biotic factors in an ecosystem using sampling techniques PAG B4: Rates of enzyme controlled reactions - Investigation of the most favourable conditions for composting PAG B7: Microbiological techniques - Investigation of the most favourable conditions for composting Total for topic 4 = 9.0 / 5.0 hours Topic B5: Genes, inheritance and selection B5.1 Inheritance 12.0/9.0 Genes, inheritance and selection – delivery guide B5.2 Natural selection and evolution 6.0/4.0 Genes, inheritance and selection – delivery guide Total for topic 5 = 18.0 / 13.0 hours Topic 6 Global challenges B6.1 Monitoring and maintaining the environment 4.0/3.0 Monitoring and maintaining the environment – topic exploration pack PAG B3: Sampling techniques - Investigation into the effects of lichen distribution against pollution PAG B3: Sampling techniques - Investigation into the effectiveness of germination in different strengths of acid rain PAG B3: Sampling techniques - Investigation of ecological sampling methods B6.2 Feeding the human race 7.0/4.0 Feeding the human race – topic exploration pack B6.3 Monitoring and maintaining health 22.0/16.0 Monitoring and maintaining health – topic PAG B7: Microbiological techniques - Investigation into growth bacterial cultures using aseptic techniques
3/4 B5.1e describe how genetic variants may influence phenotype: in coding DNA by altering the activity of a protein to include: DNA related to mutations affecting protein structure, including active sites of enzymes in non-coding DNA by altering how genes are expressed to include: DNA related to stopping transcription of mRNA (use of terms promoter, transcription factor not required) Starter Use the lighting in the class as an example. The light is analogous to a gene. The switch is analogous to the genes regulatory region. What would happen if the light bulb was broken? What would happen if the switch was broken? Main Introduce what happens to a gene when it is ‘switched on’. DNA – mRNA to protein. If the gene is not switched on then the mRNA is not produced. Therefore the protein is not produced. Use the British Library analogy In coding DNA introduce students to the genetic code. Although this is not included in the specification it may be easier to teach from this aspect. Introduce the triplet and for more able learners introduce the reason why it’s a triplet of bases.