Cochrane Methodology Register Health Technology Assessment Database NHS Economic Evaluation Database Cochrane Central Register of Controlled Trials (CENTRAL) In the Cochrane Library at ($) In the OVID EBMR collection ($) International collection of controlled trials from a variety of sources. Includes reports published in other sources not currently listed in MEDLINE or related databases. Use the Cochrane Trials register when preparing a new systematic review or searching for clinical trials from the international literature. Cochrane Database of Systematic Reviews In the Cochrane Library at ($) Abstracts only at Abstracts in PubMed In the OVID EBMR collection ($) Systematic reviews, most using meta-analysis, from the 50 Collaborative Review Groups. Focused topic summaries. Gold standard for systematic reviews. Use the Cochrane Database of Systematic Reviews to locate high quality, systematic reviews. Database of Abstracts of Reviews of Effects (DARE) Centre for Reviews and Dissemination, Univ. of York, UK Online (free) in the CRD database In the Cochrane Library at ($) OVID EBMR collection ($) Structured abstracts of critically appraised systematic reviews. Evaluations of non-Cochrane systematic reviews from a variety of sources. Use DARE when searching for additional sources of systematic reviews. DynaMed EBSCO Online ($) App available ($) Over 3,200 topics. Focuses on diagnosis and treatment options. Systematic literature surveillance process monitors over 500 journals and integrates new evidence as it is published. Extensive; updated daily. Bulleted format provides highlights from primary literature; users are encouraged to access original studies. Adheres to EBM principles – doesn’t answer questions for you. Use for finding the evidence at the point of care. Useful for tracking back to the original studies. Essential Evidence InterScience/InfoPOEMs Online ($) Filtered, synopsized, information, allowing you to search across multiple databases, including: EBM Guidelines, Daily POEMs, Integrated system for quick searching of key resources; primarily of interest to family medicine practitioners. Use Essential Evidence for “just-in-time” evidence-based answers to primary care clinical questions.
Cochrane Abstracts, Practice Guidelines, Calculators, Diagnostic Tests, and Calculators Med Ref Serv Q. 2009 Spring; 28(1):105-6. DOI: 10.1080/02763860802616144 Medicine Reviews (OVID EBMR) OVID Online ($) Single search engine for Cochrane Library files plus the ACP Journal Club. Integrated searching of core EBM databases using the OVID interface. Use OVID EBMR for a single portal to the main Cochrane Library files and ACP Journal Club Google Scholar Online (free) Searches broadly across a variety of web-based resources Easy to use; familiar tool; does not disclose exactly what sites and resources it searches. Lacks good EBM filters. When you can’t find information in other databases Guideline Clearinghouse Online (free) Evidence-based clinical practice guidelines from national and international organizations and governments. Structured abstracts (summaries) the guideline. Links to full-text guidelines, where available. Easy to use comparison table. Use guidelines.gov to find high quality practice guidelines from a variety of respected sources. J Am Acad Nurse Pract. 2003 Mar;15(3):98-101. Medscape Reference Medscape Online through Medscape Reference (free, but registration required) Medscape app available (free) Clinical knowledge base in 63 specialty areas covering thousands of diseases and disorders. Peer-reviewed disease summaries; multimedia files, clinical tools and differential diagnosis information. Academic medical center partners. Advertisements accepted. Use Medscape Reference / eMedicine for textbook style information to multiple specialties Med Ref Serv Q. 2002; Summer 21(2):47-54. DOI: 10.1300/J115v21n02_05 PubMed Clinical Queries National Library of Medicine Online (free) via PubMed – www.pubmed.gov Filters for retrieving methodologically sound studies in four categories (therapy, diagnosis, etiology, and prognosis) plus systematic reviews. Quick access for retrieving evidence-based original studies and systematic reviews from MEDLINE (based on the work of RB Haynes from McMaster). Use PubMed’s clinical queries to select evidence-based studies from the MEDLINE database.
SUMSearch 2 University of Kansas Online (free ) Meta-search engine for selected EBM resources on the Internet. Single gateway for MEDLINE, DARE, and practice guidelines; pulls feeds from First Watch and ACP Journal Club to promote current awareness. Aggregates evidence from multiple sources, but has a rudimentary interface that may be hard to use. TRIP Database Centre for Research Support (Wales) Online (free) Meta-search engine for sources of high quality internet information, including PubMed’s clinical queries, government guidelines, and e-textbooks. EBM-specific features such as a PICO search, evidence filters, and rapid review make this a relevant and interesting way to search for the best evidence. Use TRIP when seeking evidence, reviews, and guidelines. Strong UK/Canada/Australia focus. UpToDate Online ($) Concise, peer-reviewed topical summaries, chiefly in internal medicine and its subspecialties, focusing on diagnosis and treatment. An easy-to-use database that provides quick answers to clinical questions. Summaries are a combination of synthesized literature reviews and expert knowledge. Use UpToDate for answers to specific clinical questions