 TGF β-1 Causes problems in lungs, autoimmune, Neuro (tremor, learning disability, MS, TM) (need chilled tubes) Losartan, exp3179 (experimental) or VIP If  AGA, gluten free and check Tissue Trans-glutaminase 1st manifestation of autoimmunity, grain intolerance Gluten free X 3 months, then recheck  MMP9/ADH-Osm/ Androgens can all be lumped together As noted above/below Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7) ADH/Osm Thirst, skin shocks DDAVP nasal/monitor  Na Leptin Obesity, DM Improves with CIRS Tx , can  VIP, MSH MSH Sleep disturbances, chronic pain, enthesopathy, GI/malabsorption, leaky gut, prolonged illness, resistant Staph, Pituitary/Adrenal axis disruption, Reduced sex hormones, reduced ADH Due to low Leptin activity on Hypothalamus (Leptin levels may be ) VEGF Poor perfusion/cell starvation, Exercise intolerance C4a Hypoperfusion, lactosis, low glutamate/glutamine on MR Spectroscopy Brain fog, HA, myalgias, thermoregulation, Exercise intolerance Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), VIP C3a Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), VIP Androgens Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), DHEA 2) Medication Effects; Cholestyramine, Welchol Absorbs Gut Toxins BEG/Rifampin Kills MARCONS Actos/Low Amylose if Leptin >7 (otherwise Omega-3’s) Lowers MMP9, TNF, PIE-1, Leptin Losartan Lowers TGF β-1
and Cortisol Leptin SST-freeze 253.2 M; F; Amylose Leptin <2 greatly reduces MSH, on Post-Exposure day 2 ADH Lav-freeze 252x 253.2 Parallels Osm; usually both are low if edema co-exists, suspect C4a elevations In CIRS, Osm decreases before ADH decreases Serum SST-freeze 677x 253.2 DDAVP Corrects ACTH LabCorp or lav-freeze 255.41 8-37 Cortisol SST-freeze 367x 255.41 AM µg/dl PM with ACTH corrects with therapy DHEAS SST-freeze 402.x F 256.39 by red temp F 256.39 By Check Ratio SST-freeze F 256.39 by No Inhibitors
if MSH <35 Estradiol Red-freeze 82671 F 256.39 Estriol Red-freeze 82671 F 256.39 Estrone Red-freeze 82671 F 256.39 Red-freeze F 256.39 CRP LabCorp or SST-room temp 378.54 mg/L ESR Here Lav 86140 790.1 0-30 TGF β-1 LabCorp 905036 Lav Freeze (chilled poor plasma) 286.5, 279.8, 210.0 780.79 Losartan, exp3179 Consider VIP therapy to reduce TGF β-1 also work well High is bad; Indicates TIGF lowered, autoimmunity resolves, down regulates VEGF, elevations cause ANCA rise reflects cellular immunity, affects lung, brain, immune systems MMP-9 LabCorp 500124 SST-freeze 340, 780.79 PAI-1 LabCorp or Blue Freeze 437.6, 286.5, 279.8 2-14 Amylose due to cytokine release, reflects inflammation in many tissues, rises in <2-3d of exposure to toxin Lipid Pheno (RS) LabCorp SST-room temp 272.0 Amylose With MMP9 increases clotting WBC Quest Lav-room temp 285.0 5-10
C4a (not Futhan) Lav-freeze 42658 279.8, 286.5, 710.0, 780.79 in lowered by VIP therapy & Rx for CIRS, increases within 12 hours Recheck C3a and C4a monthly in treatment of PSL, consider high-dose statins with CoQa in PSL IgE SST-freeze 542x 493.01 33 U/ml Consider VIP therapy; 8,000 units for 5 doses Good indicator of mycotoxins, fog, Capillary Hypoperfusion Lyme WB (RS) LabCorp or SST-freeze 780.79 CD4+ 505008 CD25+ LabCorp 505008 lav-room temp 286.5, 279.8 Lipase SST-freeze 606x 577.8, 780.79 Low with high TGF β-1 Summarized Treatment Overview; Remove from exposure Cholestyramine for 30 days Actos run-up if Lyme) Eradicate biofilm formers/MARCoNS No gluten if AGA (+) Do Tissue Trans Glutaminase IgA, IgG, IgM if Gluten (+) Expect to find more of the IgG than IgM but measure all 3 Actos/low Amylose diet for MMP9, PAI-1, Leptin Correct ADH/Osmolality; Use if abnormal Androgens; Look at Testosterone/Estrogen to determine if up-regulated Consider DHEA Sulfate to correct from “upstream” Avoid Aromatase Inhibitors Fix C3a, C4a, TGF β-1