example of a nonbenzodiazepine sedative-hypnotic that is used in drug-facilitated sexual assault that interacts with a subtype of the GABAA receptor complex is: zolpidem. related to the anticholinergic toxidrome include all of the following except: organophosphates. symphathomimetic drug that can be a drug of but has legitimate pharmacologic use as a treatment for narcolepsy is: amphetamine. of its rapid turnaround time, the laboratory method of choice used to screen urine samples for their opiate content is: immunoassay. is subject to recreational abuse because it: blocks dopamine reuptake at synapses and prolongs the action of dopamine in the CNS, leading to feelings of euphoria. is a difficult substance to analyze in a clinical laboratory for drug assessment because: it is a difficult material to work with, and drug testing is far less standardized than for a specimen. positive urine immunoassay screening test for a drug of abuse must be confirmed by: GC-MS. best antidote for overdose with heroin is: naloxone. analysis of what enzyme activities is performed to assess neurotoxicity from organophosphate or carbamate poisoning? Acetylcholinesterase individual is brought to the hospital emergency department with nausea, vomiting, and an altered mental status. An bottle of nonprescription enteric-coated acetylsalicylic acid (aspirin) was found at her bedside by her husband 30 minutes earlier. Although all signs and symptoms point to salicylate overdose, laboratory analysis indicated no acid-base disorder and low salicylate concentration using a photometric procedure. What is the explanation of this discrepancy? The enteric-coated pills delayed aspirin absorption and blood work was collected before the salicylate could reach maximum concentration. laboratory method of analysis that is accurate and precise for very low concentrations of carbon monoxide is: gas chromatography. occurrence of cell membrane damage causing normal cells to be replaced with fibroblasts occurs in the heart because of a deficiency of what metals? Selenium blood collection for chromium or other trace metal analysis, what aspect of specimen collection is critical? Using specially manufactured collection tubes with unique stoppers blood analyte does a toxic overdose of aluminum affect? Parathyroid hormone
elements are located in which group(s) and row(s) of the periodic table? Match the disorder with the diagnostic analyte measured in the laboratory. metanephrines Urinary VMA Melatonin Urinary 5-HIAA Tumor of adrenal medullary chromaffin cells Neuroblastoma Pineal gland tumor Gastroenteropancreatic endocrine tumor Match the correct vitamin to the disorder that the vitamin deficiency would cause: Thiamine Retinol Quinone Cobalamin Beriberi Night blindness Impaired coagulation Megaloblastic anemia Match the trace or ultratrace elements with the clinical disorders associated with either deficiency or toxicity: Chromium Manganese Copper Selenium Lung cancer Parkinson disease-like symptoms Menkes disease Loss of immunocompetence Match each drug with its major therapeutic use: Imipramine Methotrexate Quinidine Lamotrigine Antidepressant Antimetabolic Antiarrhythmic Antiepileptic 204. Match each drug with its major mode of action: Amitriptyline Procainamide Phenobarbital Sirolimus Tricyclic antidepressant Antiarrhythmic Antiepileptic Immunosuppressant 205. Match the compound with the antidote for overdose: N-acetylcysteine Activated charcoal Atropine Hydroxycobalamin Acetaminophen Salicylic acid Organophosphates Cyanide 206. the compound with its metabolite: Glycolic acid Morphine Carboxylic acid Acetaldehyde Ethylene glycol Heroin Barbiturate Ethanol 207. Match the drug with its correct elimination half-life. Diazepam Heroin Cocaine . Carboxyhemoglobin 21 to 37 hours 2 to 6 minutes 30 mins to 1.5 hours 5 to 6 hours 208. Match the substance with the suggested antidote for its overdose. 232. Physostigmine 233. Ethanol
Anticholinergic agents Ethylene glycol Methemoglobinemia Benzodiazepine 234. Methylene blue 235. Flumazenil 209. Match the toxicant with its specific effect. Pesticides (carbamates) Carbon monoxide Methamphetamine Ethanol 236. Interferes with enzyme action 237. Blocks oxygen binding to hemoglobin 238. Central nervous system stimulant 239. Central nervous system depressant 210. Name the metal that might alter the results of the below analytical issue. Lead Beryllium Arsenic Chromium or False: Whole blood specimens stored at 37° C will demonstrate a falsely increased potassium value because of red blood cell hemolysis. False True or False: Dopamine in the central nervous system functions as a neurotransmitter important for regulating an overall state of attention and vigilance. False True or In the analysis of plasma porphyrins, porphyrins at neutral pH fluoresce between 610 to 640 nm. True True or The long elimination half-life of marijuana that affects the duration of detection is due to the reentry of THC from tissue fat stores into the circulation True