ASSESSMENT DETAILS APPLICANT AND NOTIFICATION DETAILS The Chemours Company (Australia) Pty Ltd (ABN: 90 169 142 750) 7 Eden Park Drive MACQUARIE PARK NSW 2113 Standard: Chemical other than polymer (more than 1 tonne per year). 75 Data items and details claimed exempt from publication: analytical data, degree of purity, impurities, use details, and import volume. 24 Variation to the schedule of data requirements is claimed as follows: melting point/freezing point, boiling point, density, vapour pressure, water solubility, hydrolysis as a function of pH, absorption/desorption, dissociation constant, acute oral toxicity, acute dermal toxicity, skin irritation, eye irritation, skin sensitisation and bioaccumulation. No USA and Europe IDENTITY OF CHEMICAL Opteon® YF CAS 754-12-1 1-Propene, 2,3,3,3-tetrafluoro- 1,1,1,2-Tetrafluoro-2-propene 1,1,1,2-Tetrafluoropropene 1234yf 2,3,3,3-Tetrafluoro-1-propene 2,3,3,3-Tetrafluoropropene 2,3,3,3-Tetrafluoropropylene HFC 1234yf HFO 1234yf R 1234yf C3H2F4 CHEMICAL
5 10 15 20 28 < 5 < 5 < 5 < 5 < 5 5 10 15 20 28 67 75 78 79 83 Remarks - Results All validity criteria for the test were satisfied. The results obtained from the toxicity control showed that the test substance did not inhibit the biodegradation of sodium benzoate, as the total oxygen consumption in the toxicity control bottles was similar to the total of oxygen consumptions by the test substance. The test substance indicated negligible biodegradation (< 5%), and therefore it is classified as not readily biodegradable. The notified chemical is not readily biodegradable. AstraZeneca (2008) Ecotoxicological Investigations toxicity to fish Notified chemical OECD TG 203 Fish, Acute Toxicity Test - Static Species Carp (Cyprinus carpio) Exposure Period 96 hours Auxiliary Solvent None Hardness Not given Analytical Monitoring Gas chromatography Concentration mg/L Number of Fish Mortality Mean measured 24 h 48 h 72 h 96 h Control 197 7 7 0 0 0 0 0 0 0 0 LC50 > 197 mg/L NOEC 197 mg/L at 96 hours. Remarks – Results All validity criteria for the test were satisfied. The results were calculated and reported based on the mean measured concentrations. Under the test conditions, the notified chemical had no lethal effect on carp at the average measured concentration of 197 mg/L. The notified chemical is not harmful to fish. B.V (2006a) Acute toxicity to aquatic invertebrates Notified chemical OECD TG 202 Daphnia sp. Acute Immobilisation Test - Static. Species Daphnia magna Exposure Period 48 hours Auxiliary Solvent None Water Hardness 250 mg CaCO3/L Analytical Monitoring Gas chromatography
Remarks - Method A stock solution was prepared by bubbling the test substance (gas) through dilution water for 3 hours at the rate of 20 mL/minute. Concentration mg/L Number of D. magna Number Immobilised Geometric mean 24 h 48 h Control 83 20 20 0 0 0 0 EC50 > 83 mg/L at 48 hours NOEC 83 mg/L at 48 hours Remarks - Results All validity criteria for the test were satisfied. Chemical analysis showed an initial concentration of 102 mg/L. At the end of the test period the concentration was 68 mg/L. Hence the geometrical mean value was calculated to be 83 mg/L. the test condition, the EC50 for Daphnia exposed to test substance was > 83 mg/L. Since no effect was recorded at this level, it can be concluded that 48 h EC50 for Daphnia is > 100 mg/L. The notified chemical is not harmful to aquatic invertebrates. NOTOX B.V (2006b) Algal growth inhibition test Notified chemical OECD TG 201 Alga, Growth Inhibition Test. Species Selenastrum capricornutum Exposure Period 72 hours Concentration Range Nominal: … mg/L Actual: … mg/L Auxiliary Solvent None Water Hardness 24 mg CaCO3/L Analytical Monitoring Gas chromatography Biomass Growth EbC50 NOEbC ErC50 NOErC mg/L at 72 h mg/L at 72 h mg/L at 72h mg/L at 72 h > 75 75 > 75 75 Remarks - Results on growth rate over the test period, the lowest observed effect concentration (LOEC) was determined to be 75 mg/L. The ErC50 is, therefore, concluded to be > 75 mg/L. Since no effect was recorded at > 75 mg/L and at a maximum average exposure of 114 mg/L in one of the treated solutions, it can be concluded that that the EC50 for algal growth is > 100 mg/L. The results were calculated and reported based on the mean measured concentrations. All validity criteria for the test were satisfied. The notified chemical is not harmful to algae.