zilongwang/ReadingBank huggingface dataset:
TABLE OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 6 4. PHYSICAL AND CHEMICAL PROPERTIES 6 5. INTRODUCTION AND USE INFORMATION 7 6. HUMAN HEALTH IMPLICATIONS 8 6.1. Exposure Assessment 8 6.1.1. Occupational Exposure 8 6.1.2. Public Exposure 8 6.2. Human Health Effects Assessment 9 6.3. Human Health Risk Characterisation 10 6.3.1. Occupational Health and Safety 10 6.3.2. Public Health 11 7. ENVIRONMENTAL IMPLICATIONS 11 7.1. Environmental Exposure & Fate Assessment 11 7.1.1. Environmental Exposure 11 7.1.2. Environmental Fate 11 7.1.3. Predicted Environmental Concentration (PEC) 12 7.2. Environmental Effects Assessment 12 7.2.1. Predicted No-Effect Concentration 13 7.3. Environmental Risk Assessment 13 Appendix A: Physical and Chemical Properties 14 Appendix B: Toxicological Investigations 16 B.1. Acute toxicity – oral 16 B.2. Irritation – skin 16 B.3. Irritation – eye 17 B.4. Skin sensitisation – mouse local lymph node assay (LLNA) 17 B.5. Repeat dose toxicity 18 B.6. Genotoxicity – bacteria 20 B.7. Genotoxicity – in vitro 21 B.8. Genotoxicity – in vitro 22 B.9. Genotoxicity – in vivo 23 B.10. Developmental toxicity 23 B.11. Metabolism 25 Appendix C: Environmental Fate and Ecotoxicological Investigations 26 C.1. Environmental Fate 26 C.1.1. Ready biodegradability 26 C.2. Ecotoxicological Investigations 26 C.2.1. Acute toxicity to fish 26 C.2.2. Acute toxicity to aquatic invertebrates 27 C.2.3. Algal growth inhibition test 28 C.2.4. Inhibition of microbial activity 29 BIBLIOGRAPHY 30
TNO (1994) Dissociation Constant pKa = 8.2 at 20 °C OECD TG 112 Dissociation Constants in Water. Remarks Titration Method CiToxLAB (2013) Flash Point 210 °C EC Council Regulation No 440/2008 A.9 Flash Point. Remarks A Cleveland open tester was used. Fukuoka (1987) Flammability Not flammable EC Council Regulation No 440/2008 A.10 Flammability (Solids). Remarks In the preliminary screening test the test substance ignited very briefly with a yellow flame and black smoke. The flame extinguished on removal of the ignition source. Therefore no further testing was required. Based on the study, the authors did not classify the substance as a readily combustible under UN Class 4, Division 4.1. Chilworth (2011)
SUMMARY The following details will be published in the NICNAS Chemical Gazette: ASSESSMENT REFERENCE APPLICANT(S) CHEMICAL OR TRADE NAME HAZARDOUS INTRODUCTION VOLUME USE STD/1599 Firmenich Limited 1-Butanone, Yes ≤ 10 tonnes per annum A fragrance ingredient CONCLUSIONS AND REGULATORY OBLIGATIONS Hazard classification on the available information, the notified chemical is recommended for hazard classification according to the Globally Harmonised System of Classification and Labelling of Chemicals (GHS), as adopted for industrial chemicals in Australia. The recommended hazard classification is presented in the following table. Hazard classification Hazard statement Sensitisation, Skin (Category 1) H317 – May an allergic skin reaction on the available information, the notified chemical is recommended for hazard classification according to the Approved Criteria for Classifying Hazardous Substances (NOHSC, 2004), with the following risk phrases: R43: May cause skin sensitisation by skin contact Human health risk assessment Provided that the recommended controls are being adhered to, under the conditions of the occupational settings described, the notified chemical is not considered to pose an unreasonable risk to the health of workers. Based on the available information, when used in the assessed pattern, the notified chemical is not considered to pose an unreasonable risk to public health. Environmental risk assessment On the basis of the reported use pattern and low expected aquatic exposure, the notified chemical is not considered to pose an unreasonable risk to the environment. Recommendations Hazard Classification and Labelling The notified chemical should be classified as follows: Sensitisation, Skin (Category 1): H317 – May cause an allergic skin reaction The above should be used for products/mixtures containing the notified chemical, if applicable, based on the concentration of the notified chemical present and the intended use/exposure scenario. The Delegate (and/or the Advisory Committee on Chemicals Scheduling) should consider the notified chemical for listing on the SUSMP.
OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 6 1. APPLICANT AND NOTIFICATION DETAILS 6 2. IDENTITY OF CHEMICAL 6 3. COMPOSITION 6 4. PHYSICAL AND CHEMICAL PROPERTIES 7 5. INTRODUCTION AND USE INFORMATION 7 6. HUMAN HEALTH IMPLICATIONS 8 6.1. Exposure Assessment 8 6.1.1. Occupational Exposure 8 6.1.2. Public Exposure 9 6.2. Health Effects Assessment 9 6.3. Human Health Risk Characterisation 10 6.3.1. Occupational Health and Safety 10 6.3.2. Public Health 10 7. ENVIRONMENTAL IMPLICATIONS 10 7.1. Environmental Exposure & Fate Assessment 10 7.1.1. Environmental Exposure 10 7.1.2. Environmental Fate 11 7.1.3. Predicted Environmental Concentration (PEC) 11 7.2. Environmental Effects Assessment 12 7.2.1. Predicted No-Effect Concentration 12 7.3. Environmental Risk Assessment 12 Appendix A: Physical and Chemical Properties 13 Appendix B: Toxicological Investigations 15 B.1. Acute toxicity – oral 15 B.2. toxicity – dermal 15 B.3. Irritation – skin 16 B.4. Irritation – eye 17 B.5. Skin sensitisation – mouse local lymph node assay (LLNA) 17 B.6. Repeat dose toxicity 18 B.7. Genotoxicity – bacteria 20 B.8. Genotoxicity – in vitro 21 B.9. Genotoxicity – in vitro 21 B.10. Genotoxicity – in vitro 23 Appendix C: Environmental Fate and Ecotoxicological Investigations 25 C.1. Ecotoxicological Investigations 25 C.1.1. Acute toxicity to fish 25 C.1.2. Acute toxicity to aquatic invertebrates 25 C.1.3. Algal growth inhibition test 26 C.1.4. Inhibition of microbial activity 27 BIBLIOGRAPHY 28
File No: STD/1609 September 2017 NATIONAL INDUSTRIAL CHEMICALS NOTIFICATION AND ASSESSMENT SCHEME (NICNAS) PUBLIC REPORT Polymer in 031556 This Assessment has been compiled in accordance with the provisions of the Industrial Chemicals (Notification and Assessment) Act 1989 (the Act) and Regulations. This legislation is an Act of the Commonwealth of Australia. The National Industrial Chemicals Notification and Assessment Scheme (NICNAS) is administered by the Department of Health, and conducts the risk assessment for public health and occupational health and safety. The assessment of environmental risk is conducted by the Department of the Environment and Energy. This Public Report is available for viewing and downloading from the NICNAS website or available on request, free of charge, by contacting NICNAS. For requests and enquiries please contact the NICNAS Administration Coordinator at: Street Address: 7, 260 Elizabeth Street, SURRY HILLS NSW 2010, AUSTRALIA. Postal Address: GPO Box 58, SYDNEY NSW 2001, AUSTRALIA. TEL: + 61 2 8577 8800 FAX: + 61 2 8577 8888 Website: www.nicnas.gov.au Director NICNAS
Appendix B: Toxicological Investigations toxicity – oral Notified chemical OECD TG 423 Acute Oral Toxicity – Acute Toxic Class Method. Species/Strain Rat/Wistar Crl: WI(Han) Vehicle Cotton seed oil Remarks - Method No significant protocol deviations Group Number and Sex of Animals Dose mg/kg bw Mortality 1 3F 2,000 0/3 2 3F 2,000 0/3 LD50 > 2,000 mg/kg bw Signs of Toxicity There were no test substance-related signs of toxicity. Effects in Organs No macroscopic findings were noted at necropsy. Remarks - Results The body weight gain of the animals was within the range commonly recorded for this strain and age. The notified chemical is of low toxicity via the oral BSL (2014a) Acute toxicity – dermal Analogue 1 (morpholine, 4-[(triethoxysilyl)methyl]-, CAS No. OECD TG 402 Acute Dermal Toxicity – Limit Test. Species/Strain Rat/HsdRccHan: WIST Vehicle None Type of dressing Occlusive Remarks - Method No significant protocol deviations Group Number and Sex of Animals Dose mg/kg bw Mortality 1 5 per sex 2,000 0/10 LD50 > 2000 mg/kg bw Signs of Toxicity - Local There were no clinical signs of local toxicity. Signs of Toxicity - Systemic There were no clinical signs of local toxicity. Effects in Organs No abnormalities were noted at necropsy. Remarks - Results The body weight gain of the animals was within the range commonly recorded for this strain and age. The analogue chemical is of low toxicity via the dermal BSL (2007) Irritation – skin (in
Harlan (2015a) Algal growth inhibition test Notified chemical OECD TG 201 Alga, Growth Inhibition Test. Species Exposure Period 72 Concentration Nominal: Control, solvent control, 0.13, 0.25, 0.5, 1.0, 2.0 and 4.0 mg/L Actual: Not determined Auxiliary Solvent Tetrahydrofuran Water Hardness 15 mg Analytical Monitoring No Remarks - Method The test substance hydrolysed rapidly in the test solutions. A measurement of total organic carbon was not reasonable due to the low test item concentrations and the use of the solvent tetrahydrofuran. Therefore, the analysis of the test concentration in the test solutions was not conducted. Growth EC50 NOEC mg/L at 72 h mg/L at 72 h > 4.0 > 4.0 Remarks - Results The validity criteria for the test are satisfied. Based on visual inspection of the test media, the solubility limit to achieve stable solutions of the test substance or its hydrolysis product was considered to be below 4.0 mg/L. No acute toxic effects was observed up to this maximum technically feasible concentration, 4.0 mg/L, of the test substance or its hydrolysis products in test water under the test conditions. Hydrolysis products of the notified chemical are not expected to be toxic to aquatic invertebrates up to the maximum technically feasible concentration Harlan
OF CONTENTS Full Public Report 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 3 4. PHYSICAL AND CHEMICAL PROPERTIES 4 5. INTRODUCTION AND USE INFORMATION 4 6. HUMAN HEALTH IMPLICATIONS 5 6.1 Exposure assessment 5 6.1.1 Occupational exposure 5 6.1.2. Public exposure 6 6.2. Human health effects assessment 6 6.3. health risk characterisation 7 6.3.1. Occupational health and safety 7 6.3.2. Public health 7 7. ENVIRONMENTAL IMPLICATIONS 7 7.1. Environmental Exposure & Fate Assessment 7 7.1.1 Environmental Exposure 7 7.1.2 Environmental fate 8 7.1.3 Predicted Environmental Concentration (PEC) 8 7.2. Environmental effects assessment 9 7.2.1 Predicted No-Effect Concentration 9 7.3. Environmental risk assessment 9 8. CONCLUSIONS AND REGULATORY OBLIGATIONS 9 Hazard classification 9 Human health risk assessment 10 Environmental risk assessment 10 Recommendations 10 Regulatory Obligations 10 Appendix A: Physical and Chemical Properties 12 Appendix B: Toxicological Investigations 15 B.1. Acute toxicity – oral 15 B.2. toxicity – dermal 15 B.3. Irritation – skin 16 B.4. Irritation – eye 16 B.5. Repeat dose toxicity 17 B.6. Genotoxicity – bacteria 19 B.7. Genotoxicity – bacteria (Prival and Mitchell modification for Azo dyes) 20 B.8. Genotoxicity – in vitro 20 B.9. Skin sensitisation – mouse local lymph node assay (LLNA) 21 Appendix C: Environmental Fate and Ecotoxicological Investigations 23 C.1. Environmental Fate 23 C.1.1. Ready biodegradability 23 C.2. Ecotoxicological Investigations 23 C.2.1. toxicity to fish 23 C.2.2. Acute toxicity to aquatic invertebrates 24 C.2.3. Algal growth inhibition test 25 Experiment A 26 Experiment B 26 C.2.4. Lemna growth inhibition test 27 C.2.5. Inhibition of microbial activity 27 Bibliography 29
TABLE OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 5 4. PHYSICAL AND CHEMICAL PROPERTIES 6 5. INTRODUCTION AND USE INFORMATION 6 6. HUMAN HEALTH IMPLICATIONS 7 6.1. Exposure Assessment 7 6.1.1. Occupational Exposure 7 6.1.2. Public Exposure 7 6.2. Human Health Effects 8 6.3. Human Health Risk Characterisation 9 6.3.1. Occupational Health and Safety 9 6.3.2. Public Health 9 7. ENVIRONMENTAL IMPLICATIONS 9 7.1. Environmental Exposure & Fate Assessment 9 7.1.1. Environmental Exposure 9 7.1.2. Environmental Fate 10 7.1.3. Predicted Environmental Concentration (PEC) 10 7.2. Environmental Effects Assessment 10 7.2.1. Predicted No-Effect Concentration 11 7.3. Environmental Risk Assessment 11 Appendix B: Toxicological Investigations 12 B.1. toxicity – dermal 12 B.2. Genotoxicity – bacteria 12 Appendix C: Environmental Fate and Ecotoxicological Investigations 14 C.1.1. Ready biodegradability test 1 14 C.1.2. Ready biodegradability test 2 14 C.2 Ecotoxicological Investigations 15 C.2.1. Acute toxicity in earthworm 15 BIBLIOGRAPHY 17
US EPA (2000) and Canada (2000) IDENTITY OF CHEMICAL AlphaPlus® C30+ HA CAS 260255-62-7 Ethene, homopolymer, distn. residues (This is defined as the complex residuum from the polymerization of ethylene in the presence of an aluminium catalyst. It consists predominately of C26 to > C80 α-olefins and boils in the range of 236 °C to 557 °C (457 °F to 1035 °F). C30+ NAO Unspecified (MW) Number average molecular weight (NAMW) is < 1000 g/mol COMPOSITION 100 % (UVCB) PHYSICAL AND CHEMICAL PROPERTIES Appearance at 20 ºC and 101.3 kPa: waxy solid Property Value Data Source/Justification Melting Point/Freezing Point > 100 °C Estimated Boiling Point > 380 °C at 101.3 kPa Estimated Density 840 kg/m3 at 15.6 °C Measured/ASTM D1298 Vapour Pressure < 1 × 10-10 psi at 100 °C Measured/ASTM D2878-95 Water Solubility 1.75 × 10-8 mg/L at 25 °C Measured by Safepharm Laboratories for analogue 3. Hydrolysis as a Function of pH Not determined Does not contain readily hydrolysable functionality. Partition Coefficient (n-octanol/water) log Pow > 8 Estimated from HEDSET database for analogue 3. Adsorption/Desorption log Koc = 8-12 Estimated by KOCWIN v2.00 for analogue 1-octacosene. Dissociation Constant Not determined Does not contain dissociable functionality. Particle Size Not determined The notified polymer is a waxy solid which is not expected to form respirable particles. Flash Point 250 °C at 101.3 kPa Measured/ Pensky-Martens closed cup Flammability Will burn in the presence of enough heat and air Estimated Autoignition Temperature 391 °C SDS Explosive properties Not determined Contains no functional groups that would imply explosive properties.
Appendix B: Toxicological Investigations Acute toxicity – oral Analogue 1 (identity in Exempt Information) OECD TG 401 Acute Oral Toxicity – Limit Test. Species/Strain Rat/Sprague-Dawley Vehicle None Remarks - Method No significant protocol deviations Number and Sex of Animals Dose mg/kg bw Mortality 1 5F 5004 0/5 2 5M 5004 0/5 LD50 > 5004 mg/kg bw Signs of Toxicity No abnormal clinical signs were noted. Effects in Organs No treatment-related macroscopic findings were noted at necropsy. Remarks - Results All animals showed expected body weight changes. The test substance is of low toxicity via the oral route. Pharmakon Acute toxicity – dermal Analogue 1 (identity in Exempt Information) OECD TG 402 Acute Dermal Toxicity – Limit Test. Species/Strain Rat/ Sprague-Dawley Vehicle None Type of dressing Semi-occlusive Remarks - Method No significant protocol deviations Number and Sex of Animals Dose mg/kg bw Mortality 1 5F 2006 0/5 2 5M 2006 0/5 LD50 > 2006 mg/kg bw Signs of Toxicity - Local No erythema or oedema was Signs of Toxicity - Systemic No abnormal clinical signs were noted. Effects in Organs No treatment-related macroscopic findings were noted at necropsy. Remarks - Results There were no treatment-related effects on body weight. The test substance is of low toxicity via the dermal route. Pharmakon (1997b) Irritation – skin Analogue 1 (identity in Exempt Information) OECD TG 404 Acute Dermal Irritation/Corrosion. Species/Strain Rabbit/New Zealand
Appendix A: Physical and Chemical Properties Melting Point/Freezing Point 1 °C ASTM D5950 Remarks The sample was heated then inserted into the automatic pour point apparatus. The sample was cooled according to the cooling profile listed in Table 1 of ASTM D5950 and examined at 1°C intervals. The lowest temperature at which movement of the sample was detected by the automatic equipment was displayed as the pour point. (EI report) Boiling Point > 271 °C at 101.3 kPa In House Testing Method - A vacuum thermogravimetric analysis was used to determine rate of sample weight change as a function of temperature. Remarks Weight loss due to evaporation begins at 271°C. (EI report) Density 818.7 kg/m3 at 20 °C ASTM using an oscillating densitometer. Remarks The sample of the test substance was introduced into a U-shaped cell which is housed in a thermostatically-controlled chamber and electromagnetically excited to oscillate at its natural frequency. When the sample was introduced into the cell, the mass of the sample changed the frequency of the cell’s oscillation and the density was calculated from this change. (EI report) Vapour Pressure 3 × 10-8 kPa at 20 °C In Method – Developed Maxwell-Bonnell Method. Remarks Using the Maxwell-Bonnell calculation in conjunction with a correlation from distillation data (software by Simulation Sciences ProVision, v.10) represents an approach to compute vapour pressures for broad boiling mixtures expected to have very low vapour pressures. (EI report) Water Solubility 0.62 µg/L at 20 °C OECD TG 105 Water Solubility Remarks Column Elution Method (EI report) Partition Coefficient (n-octanol/water) log Pow = 6.1 at 20 °C OECD TG 117 Partition Coefficient Remarks HPLC Method (EI report) Flash Point 164 °C at 101.4 kPa ASTM D93 Remarks Pensky-Martens Closed Cup Tester, was used to determine the flash point (EI report) Autoignition Temperature 341°C In house Testing Method - ASTM E-659 Auto-ignition/Hot Flame Autoignition Remarks The sample of the test substance did not produce a hot flame autoignition.
*Wicclair. Mark R 1987. Feminism, Pornography, and Censorship,” in Social Ethics Thomas A. Mappes and Jane S. Zembaty, (eds.) New York: McGraw-Hill Zerilli, 2012. “Truth and Politics” in Truth and Democracy Jeremy Elkins and Andrew (eds.) Philadelphia: University of Pennsylvania Press.
92/69/EEC A.14 Explosive Properties. SafePharm Laboratories Reactivity Remarks The chemical is not expected to have oxidising properties based on its structure and experience in use. None known any incompatibility with other substances or conditions contributing to instability. The chemical is considered to be stable. are no known hazardous decomposition products. However, the chemical is combustible and will burn if involved in a fire, evolving fumes. 7. TOXICOLOGICAL INVESTIGATIONS Endpoint and Result Assessment Conclusion Rat, acute oral LD50>2 000 mg/kg, low toxicity Rat, acute dermal LD50>2 000 mg/kg, low toxicity Rat, acute inhalation No toxicity data were submitted Rabbit, skin irritation Moderately irritating Rabbit, eye irritation Slightly irritating Guinea pig, skin sensitisation – adjuvant test Limited evidence of sensitisation. Rat, repeat dose oral toxicity – 28 days. NOAEL = 15 mg/kg/day based on the effects in blood chemistry, liver and kidney at higher dose levels. Genotoxicity – bacterial reverse mutation Non mutagenic Genotoxicity – in vitro Chromosome Aberration Non genotoxic Genotoxicity – in vivo micronucleus test Non genotoxic Human volunteers, skin irritation Non-irritating in human patch test Guinea pigs, phototoxicity Non-phototoxicity to the skin 7.1. toxicity – oral Notified chemical OECD TG 401 Oral Toxicity – Limit Test. EC Directive 84/449/EEC B.1 Acute Toxicity (Oral) – Limit Test. Species/Strain Rat/ Sprague-Dawley Vehicle None. Remarks - Method A range-finding study was performed to establish a dosing regime. No deaths were observed and systemic toxicity noted were hunched posture and lethargy with an additional sign of ataxia. Based on these observations, a dose level of 2000 mg/kg bw was selected for the main study. Group Number and Sex of Animals Dose mg/kg bw Mortality 1 5/sex 2000 None. LD50 >2000 mg/kg bw Signs of Toxicity Ataxia, hunched posture and lethargy with additional of decreased respiratory rate were seen after dosing. All animals recovered after 24 hours. Effects in Organs None. Remarks - Results None. SUBSTANCE RESULTS
Course Schedule (subject to change) Class #1 September 4 Title Introduction Topics covered Course orientation, expectations, getting to know class members Reading due None Assignment due None Class #2 September 11 Title Service: A BYU Tradition Topics covered Definitions of Service, how to write a reflection paper Reading due BYU Statement and Aims of A BYU Education Assignment due None Class #3 September 18 Motivation: Why do we serve? Topics covered Different motivations for giving service Reading due “Why Do We “The Dedication of a Lifetime”by Elder Dallin H. Oaks Assignment due Reflection Paper #1 Class #4 September 25 Title Think before you serve Topics covered Thought processes about service Reading due “The Starfish and “Starfish Hurling and Community Service” Assignment due None Class #5 October 2 Helping Change Occur Topics covered Leading Service Reading due “Helping Change by Elder Neal A. Maxwell, “Service” by Elder Steven E. Snow Assignment due Reflection Paper #2 Class #6 October 9 Title The Ethic of Care vs. Service Topics covered your Assets (Asset Based Community Development simulation) Reading due “Regenerating Community” by John L. McKnight Assignment due Reflection Paper #3
B.8. Implementation Gantt Chart Planned implementation time plan should be indicated in the Gantt Chart available in Annex 3. Table B.6.a. List of available major relevant equipment No. Equipment Date of purchase Current condition of the equipment Current uses V. Good Good Table B.6.b. List of requested major relevant equipment (price more than EGP 20,000/item) No. Instrument/spare part *Approximate cost (EGP) Proposed uses & Justification
Annex 1: Research Team Information Table (Please fill out in English): Name of Res. Team Member in English Name of Res. Team Member in Arabic University / Institute In English Position / Title % of time spent on project No. of months Incentive per month (LE) National ID No. (الرقم القومى) Number of other projects and their IDs Total % of time spent on other projects Signature
Annex 3 – Gantt chart* of the project: Project ID: PI: Affiliation: Actual start date of the project: Task No. Title of Task/Sub-task Start Date End Date Duration (Months) 1st Year 2nd Year Expected measurable outcomes of successful implementation of the task M 1 M 2 M 3 M 4 M 5 M 6 M 7 M 8 M 9 M 10 M 11 M 12 M 13 M 14 M 15 M 16 M 17 M 18 M 19 M 20 M 21 M 22 M 23 M 24 1 ………………..………….. 1.1 ……………………..…….. 1.2 ……………………………. 2 ……………………………. 2.1 ……………………………. 2.2 ……………………………. 2.3 ……………………………. 3 ……………………………. 3.1 ……………………………. 3.2 ……………………………. 4 ……………………………. 4.1 ……………………………. 4.2 ……………………………. * The above chart is given as an example. In this example, cells highlighted in yellow indicate main tasks, and cells highlighted in green indicate sub-tasks. Cells highlighted in red indicate the last months of the reporting periods. A progress/final report should be submitted shortly after the end of each period. Please add more columns (for projects longer than 24 months) and/or rows (for and sub-task) if needed.
4: (US $) Activities STDF IPPC United States Department of Agriculture Canadian Food Inspection Agency Component 1: Establishment a contract for the ePhyto Solution 0 5000 0 0 1.1 Establish project agreement Drafting, legal review, meetings, staff time 1500 1.2 Establish service agreement with lead technical unit to establish and host the system Drafting, legal review, meetings, staff time 3500 Component 2: Establishment of a GeNS for the production, sending and receipt of electronic phytosanitary certificates 231000 20000 62000 0 2.1 Finalization of the specification ESG for 5 days to develop standard 20000 UNICC to develop detailed specifications (5 days @ $600/day) 3000 2.2 Review of ASYCER for use as a GeNS UNICC to review and provide recommendation (20 days at $600/day) 12000 2.3 Evaluation of other options for use as a GeNS, if required
UNICC to review and provide recommendation, if required (30 days at $600/day) 18000 2.4 Reconfiguration of an existing system UNICC to reconfigure the system 200000 50000 testing 10000 Component 3: Establishment of an internationally accessible hub for ePhyto exchange 209000 6000 26000 0 3.1 Finalization of the specification ESG develops standard (completed prior to project approval) 6000 UNICC to develop detailed specifications (5 days @ $600/day) 3000 3.2 Establishment of the hub UNICC to obtain hardware and required software for operation of the hub 200000 Dummy testing 26000 3.3 Development of a policy framework Contractor to develop framework (10 days @ $600/day) 6000
Particle Size 0.9 - 26.31 m Determination of the particle size distribution by diffraction according to the Fraunhofer model. 1 g of the test item was mixed with 1ml of Trion-X solution and filled up to 100 ml with filtered water. The mixture was stirred then the suspension was stirred in the wet disperser for 5 minutes and measured by laser diffraction method. Range (m) Cumulative Mass (%) < 26 100 < 16 90 < 8 50 < 3 10 Remarks None BASF (2005a) Flammability Not considered to be highly flammable. EC Directive 92/69/EEC A.10 Flammability (Solids). Remarks Brief burning and rapid extinction was observed. BASF (2005b) Autoignition Temperature No self-heating detected up to 400°C EC Directive 92/69/EEC A.16 Relative Self-Ignition Temperature for Solids. Remarks None BASF (2005b)
Appendix C: Environmental Fate and Ecotoxicological Investigations Environmental Fate biodegradability Notified chemicals OECD TG 301 F Biodegradability: Manometric Respirometry Test. Inoculum Activated sludge Exposure Period 28 days Auxiliary Solvent None Analytical Monitoring The biochemical oxygen demand (BOD) was measured; The dissolved organic carbon (DOC) was measured at the beginning and the end of the test. Remarks - Method Test was conducted in triplicates at 22 ± 1˚C for up to 28 days. Aniline was used as the reference substance for reference control test. Test substance Aniline Day % Degradation Day % Degradation 7 0 7 58 28 0 28 80 Remarks - Results All criteria for test validity were met. The reference control test for aniline reached a biodegradation degree of 69% after 14 days. The notified chemicals are not considered readily biodegradable. BASF (2006c) Bioaccumulation Remarks Although the theoretical log KOW value of 7.52 for the notified chemicals indicates high potential for bioaccumulation, this is more a reflection of its very low water solubility but relatively higher (but still low) solubility in n-octanol. The low n-octanol solubility indicates low potential for the notified chemical to dissolve and accumulate significantly in fish tissue. The notifier supports this argument with reference to the Critical Body Burden concept, which establishes that the octanol solubility is well below a critical concentration (0.002×Molecular weight (g/mol)) below which a reduced uptake of the substance can be expected and toxicity is not likely. As a further supporting argument, a low bioconcentration factor (BCF) of 1.6 is calculated from the BCF model Oasis CATABOL model. Ecotoxicological Investigations Acute toxicity to fish Notified chemicals OECD TG 203 Fish, Acute Toxicity Test – Static. EC Directive 92/69/EEC C.1 Toxicity for Fish – Static. Species Danio rerio Exposure Period 96 hours
≥ 508 Da. * Assumes R = C12H25 and n = 1 Infra-red Spectrometry Remarks Major peaks at: ~ 3400, 1600, 1000 and 700 cm-1 COMPOSITION > 94% Chemical Name D-Glucopyranose, oligomeric, glycosides CAS No. 110615-47-9 Weight % 1.72% Hazardous Properties ≥ 20% Xi; R36/38 Irritating to eyes/skin. Chemical Name Alcohols, C10-16 CAS No. Weight % < 0.5% Hazardous Properties ≥ 20% Xi; R36/38 Irritating to eyes/skin. (>1% Chemical Name Sodium chloride CAS No. 7647-14-5 Weight % 3.3% Chemical Name CAS No. Weight % starting Weight % residual D-Glucopyranose, oligomeric, C10-16-alkyl glycosides 110615-47-9 70.0 5 1-Propanesulfonic acid, 3-chloro-2-hydroxy-, monosodium salt 126-83-0 30.0 0 The life of the product as sold is in excess of 2 years, with a 12 month guarantee of stability being offered to customers from the date of delivery. PHYSICAL AND CHEMICAL PROPERTIES Appearance of the notified chemical: Soft, yellowish, waxy solid. Appearance of the product Suga*Nate 160 containing the notified chemical at ≤ 40% at 20ºC and 101.3 kPa: Clear yellow viscous liquid. The following values are for the product Suga*Nate 160 containing the notified chemical at ≤ 40% unless otherwise stated. Property Value Data Source/Justification Melting Point Estimated for notified chemical Boiling Point 105oC Estimated Density 1130 kg/m3 Measured Vapour Pressure Not determined The notified chemical will not be isolated from solution which has a vapour pressure similar to water. Water Solubility 816 g/L at 20oC Measured Hydrolysis as a Function of pH Stable MSDS METHOD
Number and Number Sense 8.1 The student will compare and order real numbers. 8.2 The student will describe the relationships between the subsets of the real number system. 8.3 The student will estimate and determine the two consecutive integers between which a square root lies; and determine both the positive and negative square of a given perfect square. Computation and Estimation 8. 4 The student will solve practical problems involving consumer applications. Measurement and Geometry 8.5 The student will use the relationships among pairs of angles that are vertical angles, adjacent angles, supplementary angles, and complementary angles to determine the measure of unknown angles. 8.6 The student will a) solve problems, including practical problems, involving volume and surface area of cones and square-based pyramids; and b) describe how changing one measured attribute of a rectangular prism affects the volume and surface area. 8.7 The student will a) given a polygon, apply transformations, to include translations, reflections, and dilations, in the coordinate plane; and b) identify practical applications of transformations. 8.8 The student will construct a three-dimensional model, given the top or bottom, side, and front views. 8.9 The student will a) verify the Pythagorean Theorem; and b) apply the Pythagorean Theorem. 8.10 The student will solve area and perimeter problems, including practical problems, involving composite plane figures. Probability and Statistics 8.11 The student will compare and contrast the probability of independent and dependent events; and determine probabilities for independent and dependent events. 8.12 The student will represent numerical data in boxplots; make observations and inferences about data represented in boxplots; and compare and analyze two data sets boxplots. 8.13 The student will a) represent data in scatterplots; b) make observations about data represented in scatterplots; and
SSRM Section 18 A ERODROME MAINTENANCE SSRM Clause 18.15 OTHER REQUIREMENTS SSRM Section 19 ROAD & MARINE AMENITY MAINTENANCE SSRM Clause 19.2 OUTLINE DESCRIPTION SSRM Clause 19.5 REFERENCE STANDARD DRAWING SSRM Clause 19.7 EXTENT OF WORK SSRM Clause 19.13 MAINTENANCE OF ROAD AND MARINE AMENITY AREA TOILETS SSRM Clause 19.13.1 Toilet systems SSRM Clause 19.15 CUTTING SSRM Clause 19.15.1 Service levels for grass cutting Table 19.1 - Grass height specification SSRM Clause 19.31 OTHER REQUIREMENTS SSRM Section 20 PROTECTIVE COATINGS SSRM Clause 20.15 PROTECTIVE COATING SPECIFICATIONS - SYSTEMS AND APPROVED PRODUCTS SSRM Clause 20.16 OTHER REQUIREMENTS
SSRW Clause 21.4 OTHER REQUIREMENTS SSRW Section 22 PROTECTIVE COATINGS SSRW Clause 22.2 Protective coatings Required or not required: [enter data]. Inorganic zinc silicates coatings Required or not required: [enter data]. SSRW Clause 22.3 Protective coatings specifications - Systems and approved products ERRATA Delete “15.8”. The tables appear in Clause 22.37. SSRW Clause 22.37 Tables - Protective coatings specifications - systems and approved products Requirements are; [enter data]. SSRW Section 23 MEASUREMENT AND PAYMENT SSRW Clause 23.1 MISCELLANEOUS PROVISIONS ADDENDUM Add a new item: “23.1.9 and pedestrian shared paths. Not measured separately. Include in miscellaneous concrete SSRW Clause 23.11 MISCELLANEOUS CONCRETE 23.11.1 Footpaths ADDENDUM Add new first sentence: “Includes and pedestrian shared paths.” Add new last sentence: “Allow for reinforcement.” SSRW Clause 23.22 REQUIREMENTS
Size: Acoustic rating: Finish: SSSBW Clause 11.14 TRIM Cornice: Architraves: Skirting: SSSBW Clause 11.15 OTHER REQUIREMENTS SSSBW Section 12 SUSPENDED CEILINGS SSSBW Clause 12.4 MATERIALS AND COMPONENTS Table – Ceiling(s) Schedule Ceiling Code Type A Rondo - Balanced tee roll formed exposed system. Type B screw up ceiling suspended system Location(s) [edit] On drawings or specify here On drawings or specify here Support system(s) Exposed grid up concealed Basic grid 600 x 600 - Material [edit] Galvanized steel or aluminium Galvanized steel or aluminium Exposed members finish Factory paint finish - Exposed members colour White - Wall Trim [edit] Rondo Shadow Line or plain angle - Ceiling Lining Schedule Material:
e) examining how liberties and civil rights are protected under the law. student will apply social science skills to understand the role of the United States in a changing world by a) describing the responsibilities of the national government for foreign policy and national security; b) assessing the role of national interest in shaping foreign policy and promoting peace; and c) examining the relationship of Virginia and the United States to the global economy, including trends in international trade. student will apply social science skills to understand how world governments and economies compare and contrast with the government and the economy in the United States by a) describing the distribution of governmental power; b) explaining the relationship between the legislative and executive branches; c) comparing and contrasting the extent of participation in the political process; and d) comparing and contrasting economic systems. student will apply social science skills to understand economic systems by a) identifying the basic economic questions encountered by all economic systems; b) comparing the characteristics of traditional, free market, command, and mixed economies, as described by Adam Smith and Karl Marx; and c) evaluating the impact of the government’s role in the economy on individual economic freedoms. student will apply social science skills to understand the role of government in the Virginia and United States economies by a) describing the provision of government goods and services that are not readily produced by the market; b) describing government’s establishment and maintenance of the rules and institutions in which markets operate, including the establishment and enforcement of property rights, contracts, consumer rights, labor-management relations, environmental protection, and competition in the marketplace; c) investigating and describing the types and purposes of taxation that are used by local, state, and federal governments to pay for services provided by the government; d) analyzing how Congress can use fiscal policy to stabilize the economy; e) describing the effects of the Federal Reserve’s monetary policy on price stability, employment, and the economy; and f) evaluating the trade-offs in government decisions. student will apply social science skills to understand that in a democratic republic, thoughtful and effective participation in civic life is characterized by a) exercising personal character traits such as trustworthiness, responsibility, and honesty; b) obeying the law and paying taxes; c) serving as a juror; d) participating in the political process and voting in local, state, and national elections; e) performing public service; f) keeping informed about current issues;
OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 7 1. APPLICANT AND NOTIFICATION DETAILS 7 2. IDENTITY OF CHEMICAL 7 3. COMPOSITION 7 4. PHYSICAL AND CHEMICAL PROPERTIES 8 5. INTRODUCTION AND USE INFORMATION 8 6. HUMAN HEALTH IMPLICATIONS 9 6.1. Exposure Assessment 9 6.1.1. Occupational Exposure 10 6.1.2. Public Exposure 10 6.2. Human Health Effects Assessment 10 6.3. Human Health Risk Characterisation 13 6.3.1. Occupational Health and Safety 13 6.3.2. Public Health 14 7. ENVIRONMENTAL IMPLICATIONS 14 7.1. Environmental Exposure & Fate Assessment 14 7.1.1. Environmental Exposure 14 7.1.2. Environmental Fate 16 7.1.3. Predicted Environmental Concentration (PEC) 17 7.2. Environmental Effects Assessment 20 7.2.1. Predicted No-Effect Concentration 20 7.3. Environmental Risk Assessment 21 Appendix A: Physical and Chemical Properties 23 Appendix B: Toxicological Investigations 24 B.1. Acute toxicity – oral 24 B.2. Acute toxicity – oral 24 B.3. Acute toxicity – oral 25 B.4. Acute toxicity – dermal 25 B.5. Acute toxicity – dermal 26 B.6. Acute toxicity – inhalation 26 B.7. Irritation – skin 27 B.8. Irritation – skin 27 B.9. Irritation – skin 28 B.10. Irritation – eye 28 B.11. Irritation – eye 29 B.12. Skin sensitisation – mouse local lymph node assay (LLNA) 29 B.13. Skin sensitisation – mouse local lymph node assay (LLNA) 30 B.14. Genotoxicity – bacteria 31 B.15. Toxicity to reproduction – 90-day gavage study with one generation study 32 B.16. Toxicity to reproduction – one generation study 35 Appendix C: Environmental Fate and Ecotoxicological Investigations 37 C.1. Environmental Fate 37 C.1.1. Ready biodegradability 37 C.2. Ecotoxicological Investigations 37 C.2.1. Acute toxicity to fish (Test 1) 37 C.2.2. Acute toxicity to fish (Test 2) 38 C.2.3. Acute toxicity to aquatic invertebrates 39 C.2.4. Algal growth inhibition test 39 Appendix D: Toxicology of Perfluorohexanoic Acid (PFHxA) 41 BIBLIOGRAPHY 43
water, mountain ranges, and cities. 4. Identify some important historical and legendary figures, events, and historical timelines, such as Romulus, the founding of Rome, and the three periods of Roman history. 5. Participate in simulated cultural activities, such as family celebrations, banquets, and festivals. LI.4 The student will recognize that perspectives, practices, and products of Roman culture are interrelated. 1. Recognize that products of the Roman world reflect practices and perspectives of Roman culture, such as justice, the toga as the symbol of Roman citizenship and aqueducts as a symbol of Roman innovation. 2. Examine ways geography and history influenced practices and perspectives of the Romans, such as the founding of Rome near the Tiber River and conquest of the Mediterranean. Making Connections through Language LI.5 The student will connect information about the Latin language and Roman culture with concepts studied in other subject areas. 1. Give examples of the use of Latin derivatives, numerals, mottoes, phrases, and symbols in other subject areas. 2. Relate content from other subject areas to topics discussed in Latin class, such as mythology, current events, geography, history, art, and architecture. Linguistic and Cultural Comparisons LI.6 The student will compare basic elements of the Latin language to those of the English language. 1. Recognize that the basic language patterns of Latin differ significantly from those of English. 2. Recognize and interpret the Latin roots, prefixes, and suffixes that appear in English words. 3. Compare and contrast the systems of Latin and English. LI.7 The student will demonstrate understanding of the significance of culture through comparisons of the cultures of Rome and the United States. 1. Compare and contrast elements of the cultures of Rome and the United States, such as eating habits, clothing styles, educational practices, architectural styles, and family and social structures. 2. Demonstrate an awareness of unique elements of the student’s own culture. Interacting in School and Global Communities LI.8 The student will to apply knowledge of the Latin language and Roman culture beyond the classroom setting to explore recreational, educational, and occupational opportunities. 1. Present examples of the Latin language and classical Roman culture evident in media, entertainment, and occupations.
Cultural Perspectives, Practices, and Products NWII.7 The student will demonstrate understanding of the perspectives, practices, and products of the culture(s) studied. 1. Participate in authentic or simulated cultural activities, such as family gatherings, holiday celebrations, and community events. 2. Identify and discuss patterns of behavior typically associated with the target culture(s), such as business practices, customs, traditions, and family dynamics. 3. Explore the influence of the geography and history of the countries studied on cultural elements, such as food, clothing, dwellings, transportation, language, music, and art. Making Connections through Language NWII.8 The student will use information acquired in the study of the target language and information acquired in other subject areas to reinforce one another. 1. Give examples of the influence of the target language and culture(s) on other subject areas. 2. Compare information acquired in other subject areas to topics discussed in the target language class. Linguistic and Cultural Comparisons NWII.9 The student will compare and contrast elements of the target language with those of English and other languages. 1. Recognize critical sound distinctions and intonation patterns in the target language and in English and their effects on the communication of meaning. 2. Compare the diverse and unique aspects of language-specific vocabulary and structural patterns of the target language and of English. NWII. 10 The student will demonstrate understanding of similarities and differences between the culture(s) studied and those of the United States. 1. Identify similarities and differences of traditions of the target-language culture(s) and those of the United States, such as, holidays, food, family, and celebrations. 2. Identify similarities and differences of geography and the impact on aspects of culture, such as food, clothing, dwellings, transportation, recreation, and art. Interacting in School and Global Communities NWII.11 The student will improve target-language skills and cultural knowledge in opportunities beyond the classroom setting for recreational, educational, and occupational purposes. 1. Explain aspects of the target culture(s) discovered through interaction with target-language speakers, and authentic media or technology. 2. Use target-language resources, such as individuals and organizations in the community or technology, to reinforce cultural knowledge.
Experience the richness and excitement of scientific discovery of the natural world through the collaborative quest for knowledge and understanding. Make informed decisions regarding contemporary issues, taking into account the following: public policy and legislation; economic costs/benefits; validation from scientific data and the use of scientific reasoning and logic; respect for living things; personal responsibility; and history of scientific discovery. Develop scientific dispositions and habits of mind including: curiosity; demand for verification; respect for logic and rational thinking; consideration of premises and consequences; respect for historical contributions; attention to accuracy and precision; and patience and persistence. Develop an understanding of the interrelationship of science with technology, engineering and mathematics. Explore science-related careers and interests. K-12 Safety In implementing the Science Standards of Learning, teachers must be certain that students know how to follow safety guidelines, demonstrate appropriate laboratory safety techniques, and use equipment safely while working individually and in groups. Safety must be given the highest priority in implementing the K-12 instructional program for science. Correct and safe techniques, as well as wise selection of experiments, resources, materials, and field experiences appropriate to age levels, must be carefully considered with regard to the safety precautions for every instructional activity. Safe science classrooms require thorough planning, careful management, and constant monitoring of student activities. Class enrollment should not exceed the designed capacity of the room. Teachers must be knowledgeable of the properties, use, and proper disposal of all chemicals that may be judged as hazardous prior to their use in an instructional activity.
SCHEDULED JOBS Scheduled Jobs are maintained by the OTIS DBA section; the primary mechanism for scheduling database jobs is by UNIX crontab. The developer is responsible for creating the SQL to be run by the crontab, creating the UNIX scripts for executing the SQL, and consulting with the DBA section to ensure the UNIX code will function in the DEP environment. All code must be reviewed and approved by the OTIS DBA section. The following rules apply to Scheduled Jobs: Scheduled Job are mandatory. Scheduled Job names must begin with the schema name for which the job is being run. It cannot exceed 30 characters. It should be made up of real words. It must contain a section at the top with comments on when the script was written, who wrote it, and a description of the function that the script performs. If the script is one of several used for a purpose then all script names should be declared in the top comment section along with the order in which the current script is run in relation to the other scripts. examples are PA_LOAD_PERMIT_DATA, CRA_CALCULATE_FEES. The Scheduled Job includes underscores in of spaces. When the Scheduled Job name is only one word, it must not be an . The executed SQL code must be stored in a database procedure or database package. The Scheduled Job must execute under the schema account which owns the database procedure or package. The Scheduled Job may contain UNIX commands to create files, ftp files, and/or remove files only from the directory location where the scripts are stored. Exceptions may be made if a business case is presented and approved by the OTIS DBA section. Developers are responsible for testing the UNIX shell scripts from their own UNIX account on the DEP development database server before submitting them to be added to the crontab. SQL CODING STANDARDS and GUIDELINES Database object SQL and PL SQL code is maintained by the developer and is expected to adhere to general best-practice coding standards. There are multiple references online for those consulted for the standards/guidelines found below are: Burleson Consulting:
Unit Code Title of Unit of Competency (UOC) NB Give details of any matters agreed under clause 5 against relevant UOC Nominal Hours Delivery Site RTO School TTC Scored Assessment (Yes or No ) Number of Enrolments For delivery other than the School Council’s premises: Unit Code Site of Delivery Venue Address Contact Person Contact Number