OF CONTENTS FULL PUBLIC REPORT 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 4 4. INTRODUCTION AND USE INFORMATION 4 5. PROCESS AND RELEASE INFORMATION 4 5.1. Distribution, transport and storage 4 5.2. Operation description 4 5.3. Occupational exposure 4 5.4. Release 5 5.5. Disposal 5 5.6. Public exposure 5 6. PHYSICAL AND CHEMICAL PROPERTIES 6 6.1 Comments on physico-chemical properties 9 7. TOXICOLOGICAL INVESTIGATIONS 9 7.1. toxicity – oral 9 7.2. toxicity – dermal 10 7.3. Acute toxicity – inhalation 10 7.4. Irritation – skin 10 7.5. Irritation – eye 11 7.6. Skin sensitisation 12 7.7. 28-day repeat dose oral toxicity 13 7.8. Genotoxicity – bacteria 15 7.9. Genotoxicity – in vitro 15 7.10. Genotoxicity – in vivo 16 8. ENVIRONMENT 18 8.1. Environmental fate 18 8.1.1. Ready biodegradability 18 8.1.2. Bioaccumulation 18 8.2. Ecotoxicological investigations 18 8.2.1. Acute toxicity to fish 18 8.2.2. Acute toxicity to aquatic invertebrates 19 8.2.3. Algal growth inhibition test 20 8.2.4. Inhibition of microbial activity 20 9. RISK ASSESSMENT 22 9.1. Environment 22 9.1.1. Environment – exposure assessment 22 9.1.2. Environment – effects assessment 22 9.1.3. Environment – risk characterisation 22 9.2. health 23 9.2.1. Occupational health and safety – exposure assessment 23 9.2.2. Public health – exposure assessment 23 9.2.3. Human health – effects assessment 23 9.2.4. Occupational health and safety – risk characterisation 24 9.2.5. Public health – risk characterisation 24 10. CONCLUSIONS – ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND HUMANS 25 10.1. Hazard classification 25 10.2. Environmental risk assessment 25 10.3. Human health risk assessment 25 10.3.1. Occupational health and safety 25 10.3.2. Public health 25 11. MATERIAL SAFETY DATA SHEET 25 11.1. Material Safety Data Sheet 25 11.2. Label 25 12. RECOMMENDATIONS 26 12.1. Secondary notification 27 13. BIBLIOGRAPHY 27
Flammability Not highly flammable EC Directive 92/69/EEC A.10 Flammability (Solids). Remarks The notified chemical could not be ignited with a flame. The test material coloured black and emitted sparks and black smoke upon contact with the ignition source. Notox (1998e) Not likely to react or produce flammable gas on contact with water Statement based on structure of chemical. Remarks The notified chemical does not contain groups that may lead to evolution of highly flammable gases in dangerous quantities. Experience in handling demonstrated that the notified chemical does not react with water. (1998f) Not pyrophoric Statement on structure of chemical. Remarks The notified chemical does not contain any chemical that may lead to spontaneous ignition a short time after coming into contact with air at room temperature. Experience in handling demonstrated that the notified chemical does not ignite upon contact with air. (1998g) Autoignition Temperature > 400oC 92/69/EEC A.16 Relative Self-Ignition Temperature for Solids. Remarks The test substance was heated from room temperature to 400oC. No endothermic or exothermic reaction was noted during the test. Notox (1998h) Explosive Properties Not explosive Statement based on structure of chemical. Remarks The notified chemical does not contain any chemically unstable or highly energetic groups that might lead to an explosion. Notox (1998i) Oxidizing Properties Not oxidising Statement based on structure of chemical. Remarks The notified chemical does not contain any that might act as an oxidising agent. (1998j) Reactivity Not highly reactive Remarks The notifier states that the notified chemical is considered to be stable. It is combustible, and will produce noxious fumes in a fire. However, there is no experimental evidence to demonstrate anticipated combustion products. Surface Tension 72.9 mN/m at 20oC OECD TG 115 Surface Tension of Aqueous Solutions. EC Directive 92/69/EEC A.5 Surface Tension. Remarks Concentration: 1.108 g/L