Appendix A: Physical and Chemical Properties Melting Point/Freezing Point >1100 °C OECD TG 102 Melting Point. Remarks The capillary / metal block method was used up to 400oC, followed by heating in a muffle oven up to 1100°C. No melting was observed. LAUS GmbH (2012e) Density 3716.5 kg/m3 at 20 °C OECD TG 109 Density of Liquids and Solids. Remarks The study was carried using the pycnometer method, with a fitted thermometer. At all weighings, the corresponding temperature was recorded. LAUS GmbH (2012c) Water Solubility 0.023 – 0.27 g/L at 20 °C OECD TG 105 Solubility. EC Council Regulation No 440/2008 A.6 Solubility. Remarks Flask Method. The solubility of test substance in water was determined from the measured concentrations of aluminium (Al) and molybdenum (Mo) in the filtered test solutions. The concentration of the test substance in water based on Al and Mo were 23–269 mg/L and 24–263 mg/L respectively. The nominal concentration of the test substance in water was 50–700 mg/L. The solubility of the notified chemical was dependent on nominal loading. LAUS GmbH (2012f) Particle Size Median 12 m OECD TG 110 Particle Size Length and Diameter Distributions. Particle size(m) Volume (%) < 3.25 10 < 11.92 50 < 44.91 90 Remarks The notified chemical particle size was determined by dispersion and laser diffraction measurement using the Malvern Mastersizer 2000. The median particle size L50 = 12 m (11.92 m). However, The notified chemical will be imported into Australia in matrix particles >100 µm. Möller, M. (2012) Solid Flammability Not highly flammable EC Council Regulation No 440/2008 A.10 Flammability (Solids). (EU-Method A. 10 and UN N.1, 2009). Remarks No ignition occurred within two minutes after heating the notified chemical with the Teclu burner flame. Only glowing and a small carbonisation were observed during heating. LAUS GmbH (2012d) Autoignition Temperature Not auto-flammable EC Council Regulation No 440/2008 A.16 Relative Self-Ignition Temperature for Solids. (EU-Method A.16).
Appendix B: Toxicological Investigations toxicity – oral Notified Chemical OECD TG 423 Acute Oral Toxicity – Acute Toxic Class Method. Species/Strain Rat/Sprague Dawley Vehicle oil Remarks - Method No protocol deviation occurred during the study. Group Number and Sex of Animals Dose mg/kg bw Mortality 1 3 F 2000 0 2 3 F 2000 0 LD50 >2000 mg/kg bw Signs of Toxicity No clinical signs were observed Effects in Organs None Remarks - Results No treatment related changes were observed The notified chemical is of low toxicity via the oral route. Colas, S. (2011b) toxicity – dermal Notified Chemical OECD TG 402 Dermal Toxicity. Species/Strain Rat/ Sprague Dawley Vehicle Type of dressing Occlusive/Semi-occlusive. Remarks - Method No protocol deviation occurred during the study. Group Number and Sex of Animals Dose mg/kg bw Mortality 1 5 M, 5 F 2000 0 LD50 >2000 mg/kg bw of Toxicity - Local No cutaneous reactions were observed of Toxicity - Systemic No systemic clinical signs were observed Effects in Organs None Remarks - Results No treatment related changes were observed The notified chemical is of low toxicity via the dermal route. Colas, S. (2011a) Irritation – skin Notified Chemical OECD TG 404 Acute Dermal Irritation/Corrosion. Species/Strain Albino Rabbit/New Zealand White