strategies for the labeling of research samples is discussed in Section 5.9 of the CHP. These same strategies can be used when labeling secondary chemical containers as well. Chemical Segregation All chemicals must be stored according to chemical compatibility. Once segregated by chemical compatibility, they can then be stored alphabetically. Information regarding chemical compatibility can be in the SDS, primarily in Section 7, “Handling and Storage” and Section 10, “Stability and Reactivity”. If unsure of proper segregation procedures, contact the Laboratory Supervisor for assistance. Chemical segregation can be achieved by either isolation (e.g., organic solvents stored in a flammable cabinet), physical distance (e.g., acids and bases are stored on opposite sides of a chemical storage room), or secondary containment (e.g., placing oxidizing acids such as nitric acid into a secondary containment to segregate from organic acids such as formic acid as shown in Figure 5.7). In the most general terms, proper segregation can be achieved by: Storing acids away from bases and toxics; Storing oxidizers away from organic chemicals; and Storing reactive and acutely toxic materials away from all other chemicals. Table 5.1 illustrates a more detailed chemical compatibility logic that can be used for chemical storage. Hazard classes marked by an X need to be segregated from each other (e.g., Acid, inorganic must be segregated from Base, inorganic). Contact REM at (765) 49-40121 with questions regarding chemical segregation. Table 5.1 – Chemical Compatibility Chart Acid, inorganic Acid, organic Acid, oxidizer Base, inorganic Base, organic Oxidizer Toxic, inorganic Toxic, organic Reactive Organic solvent Acid, inorganic X X X X X Acid, organic X X X X X X X Acid, oxidizer X X X X X X X Base, inorganic X X X X Base, organic X X X X X Oxidizer X X X X X
Sharps Waste Sharps are items capable of puncturing, cutting, or abrading the skin such as glass or plastic pipettes, broken glass, test tubes, petri dishes, razor blades, needles, and syringes with needles. Sharps waste contaminated with hazardous chemicals must be placed into puncture resistant containers (e.g., sharps container, plastic or metal container with lid) and properly labeled as detailed in Chapter 4 of the Purdue University Hazardous Waste Guidelines. All chemically contaminated waste should be inventoried on a Hazardous Materials Pickup Request Form and sent to REM for proper disposal. Clean uncontaminated broken glassware and plastic sharps should be placed in a corrugated cardboard box or other strong disposable container. Do not exceed 20 pounds. When ready for disposal, the box should be taped shut and prominently labeled as “Sharp Objects/Glass – Discard” or similar wording. The “Safe for Disposal” label (Figure 7.5) should also be affixed to the outside of the container. Contact your Physical Facilities Building Services department for specific non-hazardous waste disposal instructions. More detail regarding sharps, including biologically contaminated sharps, can be found at the found in the REM Sharps and Infectious Waste Handling and Disposal Guidelines. () Liquid Chromatography Waste Liquid chromatography (LC) is an analytical technique used to separate, identify, quantify, and purify individual components of a mixture. This technique is very common in biological and chemical research. The most common type of LC at Purdue is High Performance Liquid Chromatography (HPLC). Purdue has numerous LC instruments located in laboratories all over campus. Because organic solvents (e.g., methanol, acetonitrile) are commonly used in the process, most LC waste is regulated by the EPA as hazardous waste. Consequently, all containers collecting LC waste must remain closed while the LC unit is in operation. It is neither acceptable to place a waste line running from the LC unit into an open waste container nor is it acceptable to use foil or Parafilm® as a means of closure as shown in Figure 7.8. Open Waste Foil Parafilm® Figure 7.8 – Improper LC Collection Practices One of the following practices must be employed in to comply with hazardous waste regulations for LC waste collection systems:
Diacetylene Methylcyclopentane ether Group C chemicals consist of monomers which form peroxides that can initiate explosive polymerization. Inhibited monomers should be tested before use and discarded after 12 months. Uninhibited monomers should be discarded 24 hours after opening. Table C.3 – Group C Chemicals Acrylic acid Styrene Acrylonitrile Tetrafluoroethylene Butadiene Vinyl acetate Chloroprene Vinyl acetylene Chlorotrifluoroethylene Vinyl chloride Methyl methacrylate Vinyl pyridine General Guidelines Solvents containing inhibitors should be used whenever possible. All peroxide forming solvents should be tested prior to distillation. Peroxide forming solvents should be purchased in limited quantities. Peroxide forming solvents should be marked with the purchase date and the date opened. Peroxide forming solvents should be sealed tightly and stored away from light and heat. Periodic testing should be done on opened containers and the results marked on the containers. Testing Obtain test strips for the of 0-100 ppm peroxide. Record the test results on the bottle. If the test results are 100 ppm or greater, contact REM (765-49-40121) for proper disposal.
acetylides aluminum ophorite explosive amatol ammonal ammonium nitrate ammonium perchlorate ammonium picrate ammonium salt lattice butyl tetryl calcium nitrate copper acetylide cyanuric triazide cyclotrimethylenetrinitramine dinitroethyleneurea dinitroglycerine dinitrophenol dinitrophenolates dinitrophenyl hydrazine dinitrotoluene dipicryl sulfone dipicrylamine erythritol tetranitrate fulminate of mercury fulminate of silver fulminating gold fulminating mercury fulminating platinum gelatinized nitrocellulose guanyl nitrosamino guanyltetrazene guanyl nitrosamino guanylidene hydrazine guanylidene heavy metal azides hexanite hexanitrodiphenylamine hexanitrostilbene hexogen hydrazine mixtures hydrazinium nitrate hydrazoic acid lead azide lead mannite lead mononitroresorcinate lead picrate lead salts lead styphnate magnesium ophorite mannitol hexanitrate mercury oxalate mercury tartrate nitrated carbohydrate nitrated glucoside nitrated polyhydric alcohol nitrogen trichloride nitrogen tri-iodide nitroglycerin nitroglycide nitroglycol nitroguanidine nitroparaffins nitronium perchlorate nitrotoluene nitrourea organic amine nitrates organic nitramines organic peroxides (t-butyl peroxide) picramic acid picramide picric acid picryl chloride picryl fluoride polynitro aliphatic compounds potassium nitroaminotetrazole silver acetylide silver azide silver styphnate silver tetrazene sodatol sodium amatol sodium dinitro-ortho-cresolate sodium/potassium nitrate explosive mixtures sodium picramate syphnic acid tetrazene tetranitrocarbazole tetrytol trimonite trinitroanisole trinitrobenzene trinitrobenzoic acid trinitrocresol trinitronaphthalene trinitrophenetol trinitrotoluene tritonal urea nitrate
Supervisor: Supervisor classification, department: Name/type of training: Date: ______________________ Duration: Person administering training: Elements of the training (list topics covered, give details if appropriate) Quiz/test performance ________ or mark here [ ] to indicate no testing. Signed: __________________________________________________ (Person Administering Training) Signed: __________________________________________________ (Supervisor) The School and the Department are responsible for ensuring that supervisors -- usually, but not always faculty -- are accountable for the safety training of staff, and are able to produce adequate and complete safety training records for all staff upon request. The training need not be administered by the supervisor, but the supervisor is ultimately responsible for making it happen.