Performance in Delivering Clinical Research MREC Number IRAS Number Trial Name Target Number Of Patients Agreed? Minimum Number Of Patients Agreed Maximum Number Of Patients Agreed Target Date To Recruit Patients Agreed? Date Agreed to recruit target number of patients Total Number Of Patients Recruited At Agreed Target Date Date That The Trial Closed To Recruitment Total Number Of Study Participants Recruited Reason For Closure Of Trial 16/SC/0018 191267 Study of CTX 4430 in Cystic Fibrosis Patients Target Agreed 2 2 Date Agreed 2 01/07/2017 09/05/2017 2 Withdrawn By Host 16/YH/0154 202759 CHIL 4975 A Multicenter, Randomized, Parallel-group, Prospective Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Subjects Due to Acute Gastroenteritis Target Agreed 10 10 Date Agreed 0 18/10/2018 26/07/2017 0 Withdrawn By Host 16/EM/0386 211113 AMG334 Target Agreed 4 4 Date Agreed 1 08/03/2019 04/05/2017 1 Withdrawn By Sponsor 16/LO/1578 212991 BMX Alpha Registry Target Agreed 50 50 Date Agreed 50 30/09/2017 08/05/2017 50 Recruitment Finished 14/LO/2101 165015 NEUR 3835 Target Agreed 7 7 Date Agreed 0 30/05/2017 26/04/2017 0 Recruitment Finished 16/EE/0195 200168 CANC - 5156 Target Agreed 4 4 Date Agreed 1 30/06/2018 19/06/2017 1 Withdrawn By Host 15/WM/0457 195511 CANC 5294 Target Agreed 5 5 Date Agreed 6 01/12/2017 19/05/2017 6 Recruitment Finished 16/LO/0886 204525 101SK202 Acute Stroke Target Agreed 3 3 Date Agreed 12 08/09/2017 08/09/2017 12 Recruitment Finished 17/EM/0006 216496 ALD403 for Chronic Migraine Prevention Target Agreed 7 7 Date Agreed 3 14/05/2018 05/07/2017 3 Recruitment Finished 16/LO/1215 204366 CRIT 4527 (Super-Refratory Status Epilepticus) Target Agreed 2 2 Date Agreed 1 31/10/2017 11/07/2017 1 Recruitment Finished
16/EE/0243 207331 A 6 Month Multicentre Phase 3, Open-Label extension Safety Study of OTO-104 Target Agreed 3 3 Date Agreed 5 01/11/2017 06/09/2017 5 Recruitment Finished 16/EE/0009 189564 CANC - 4940 Target Agreed 2 2 Date Agreed 0 11/08/2017 26/07/2017 0 Recruitment Finished 14/WS/1146 166537 STRO 3595 NAVIGATE ESUS Target Agreed 15 15 Date Agreed 26 20/09/2017 20/09/2017 26 Recruitment Finished 15/EE/0047 168114 STRO 4441 PHADER Target Agreed 20 20 Date Agreed 15 30/06/2018 30/09/2017 15 Recruitment Finished 16/EE/0011 194393 PHASE III OTONOMY STUDY Target Agreed 3 3 Date Agreed 2 30/07/2017 21/07/2017 2 Recruitment Finished 16/SC/0390 190073 NEUR 5596 NEUR 5551 Target Agreed 3 3 Date Agreed 0 31/12/2017 12/12/2017 0 Recruitment Finished 16/LO/0285 199031 GAST 5487 Target Agreed 6 6 Date Agreed 9 31/08/2017 01/08/2017 9 Recruitment Finished 15/LO/0894 180555 NEUR 4110 Target Agreed 4 4 Date Agreed 2 28/11/2017 28/11/2017 2 Recruitment Finished 16/EE/0357 206501 OPTIPARK Target Agreed 10 10 Date Agreed 10 22/12/2017 22/12/2017 10 Recruitment Finished 15/YH/0535 190077 TRANSITION_LCZ696 PRE/POST DISCHARGE IN ACUTE HEART FAILURE Target Agreed 5 5 Date Agreed 0 31/10/2017 31/10/2017 0 Recruitment Finished 16/SS/0134 199690 STRO 4724 Target Agreed 1 1 Date Agreed 0 01/12/2017 17/11/2017 0 Recruitment Finished 14/NW/1258 161891 NCRN - 3041: ODM-201 IN MEN WITH HIGH RISK OF NON METASTATIC CASTRATION RESISTANT PROSTATE CANCER Target Agreed 4 4 Date Agreed 1 31/12/2017 09/02/2018 1 Recruitment Finished 16/SC/0494 211989 Triple vs dual therapy in inadequately controlled asthma Target Agreed 8 8 Date Agreed 0 31/01/2018 31/01/2018 0 Recruitment Finished
16/YH/0506 212039 COPD Exacerbation study Target Agreed 1 1 Date Agreed 0 31/01/2018 22/12/2017 0 Recruitment Finished 17/EM/0044 217658 MUSC 5107 Target Agreed 5 5 Date Agreed 2 18/05/2018 21/02/2018 2 Recruitment Finished 17/LO/0380 218003 CREAD 2 Target Agreed 3 3 Date Agreed 0 31/07/2018 31/01/2018 0 Recruitment Finished 16/EE/0463 214371 CompLEEment-1 Target Agreed 3 3 Date Agreed 4 05/12/2018 16/10/2017 4 Recruitment Finished 17/SC/0237 220963 Investigation of BI 1467335 Target Agreed 2 2 Date Agreed 0 26/09/2018 08/03/2018 0 withdrawn by sponsor