TABLE OF CONTENTS STUDY CLINICAL TRIAL (N=160) BASIC SCIENCE/VIROLOGY (N=91) Clinical Trials Community AIDS Resource, Inc. (Care Resource) MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY ViiV HealthCare/Pfizer - A4001095: A multicenter, randomized, double-blind, comparative trial of Maraviroc+Darunavir /Ritonavir PI: Steven Santiago, M.D Contacts for further information: Recruitment Begins 9/15/2011 MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY ELIGIBILITY :
UNIVERSITY OF CENTRAL Presenter: Alexander M. Cole, Ph.D. clinical Trial Contract with HIV Vaccine Trials Network (HVTN) and to process specimens for study# HVTN505 Alexander M. Cole, Ph.D. (PI of lab contract); , M.D. (PI of clinical contract) Microbiology and Molecular Biology cGLP laboratory processing for clinical trial NOVA SOUTHEASTERN UNIVERSITY –6 Studies Presenter: , Ph.D. clinical Trial Young Hispanic Men – Entre Culturas: Navigating Culture, Identity and HIV Risk Maria Isabel Fernandez, Ph.D. G. Stephen Bowen, M.D. College of Osteopathic Medicine HIV prevention among young Hispanic/Latino MSM clinical Trial Project POWER: A Health Promotion and HIV Risk Reduction Intervention for Black Men. Maria Isabel Fernandez, Ph.D College of Osteopathic Medicine HIV prevention among black men who have sex with men and women clinical Trial Adolescent Trials Network for HIV interventions Maria Isabel Fernandez, Ph.D. G. College of Osteopathic Medicine HIV and adolescents (both infected and at risk for HIV) clinical Trial Risk Reduction for Urban Substance Using MSM Steven P. Kurtz, Ron Stall, Hilary L. Surratt Division of Applied Interdisciplinary Studies HIV, MSM, drug use National Institute on Drug Abuse Grant # DA024579 clinical Trial A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV Steven P. Kurtz, Hilary L. Surratt Division of Applied Interdisciplinary Studies HIV, young adults, drug use National Institute on Drug Abuse Grant # DA019048 clinical Trial Case Management Alternatives for African American Women at High Risk for HIV Hilary L. Surratt, Gladys Ibanez Division of Applied Interdisciplinary Studies HIV, women, drug use National Institute on Drug Abuse Grant # DA013131 University of Miami Department of Medicine, Division of Infectious Diseases
Clinical , 7th Floor MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY Tibotec. A single arm open label study to assess the pharmacokinetics of Rilpivirine in HIV-1 pregnant women. P.I.: Salih Yasin, M.D. Contact for further information: Yvette Rivero 305/243-2169 Enrollment open MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY Eligibility: Women ≥ 18 years of age who have never taken antiretroviral drugs and are between 18-24 weeks pregnant. MEDICATION TRIALS: Treatment experienced (history of Current or Past Use of Antiretroviral Therapy) Tibotec. A single arm open label study to assess the pharmacokinetics of Darunavir/Ritonavir and/or Etravirine in HIV-1 pregnant women P.I.: Salih Yasin, M.D. Contact for further information: Yvette Rivero 305/243-2169 Enrollment open MEDICATION TRIALS: Treatment experienced (history of Current or Past Use of Antiretroviral Therapy) Eligibility: Women ≥ 18 years of age, with a history of taking antiretroviral drugs, who are between 18-24 weeks pregnant. Wohlfeiler, Piperato & Associates, LLC MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY Sangamo Biosciences (selected as site – details pending) P.I.: Michael Wohlfeiler, M.D. Contact for further information: Daniel Guzman, CRC 305/538-1400 ext: 222 Selected as a site – waiting for contract approval MEDICATION TRIALS: Treatment Naïve – No PAST USE OF ANTIRETROVIRAL THERAPY Eligibility: Men and women > 18 years of age never taken antiretroviral drugs and have a viral load > 2,500
Antiretroviral Therapy) efficacy and safety of simplifying therapy from a regimen of atazanavir (ATV) + ritonavir (RTV) + tenofovir/emtricitabine (TDF/FTC) to a regimen of ATV + abacavir sulfate/lamivudine (ABC/3TC) without RTV in virologically suppressed, HIV-1 infected subjects. Contact for further information: Daniel Guzman, CRC 305/538-1400 ext: 222 Eligibility: Men and women > 18 years of age. 1) TDF/3TC + ATV/r (300/100 mg) must be patient’s initial antiretroviral regimen or the first or second switch regimen, 2) virologically suppressed on TDF/FTC + ATV/r, 3) must be HLA-B*5701 negative. Trials for HIV-Associated Conditions Salix Pharmaceuticals – CFHD3092: This study is being conducted to evaluate the safety and tolerability of crofelemer 125 mg twice a day, taken orally, over 48 weeks of therapy in human immunodeficiency virus-positive (HIV+) subjects with diarrhea. P.I.: Michael Wohlfeiler, M.D. Contact for further information: Daniel Guzman, CRC 305/538-1400 ext: 222 Enrollment open Trials for HIV-Associated Conditions Eligibility: HIV-infected adults who have been on antiretroviral therapy for at least 4 weeks prior to screening with self-reported presence of diarrhea Miami Beach Community Health Center, Inc. Trials for HIV-Associated Conditions KOWA Research Institute – NK-104-4.05US: A study comparing Pitavastatin (4 mg.) vs. Pravastatin (40 mg.) in subjects with dyslipidemia. P.I.: Mark Keller, M.D. Contact for further information: Alice Lopez 305/866-8915 Enrollment open Trials for HIV-Associated Conditions E ligibility: HIV-infected men and women, ages 18-70, who have taken antiretroviral drugs for at least 6 months. LDL > 130 mg. and < 220 mg. and triglyceride levels < 400. , AIDS Clinical Research Unit , Room 2016
copies/ml and CD4 cell count ≥ 200 UNIVERSITY OF – 28 Studies Presenter: , M.D. clinical Trial Adolescent Medicine Trials Network for HIV/AIDS Interventions, aka ATN (longstanding collaborative NIH research consortium continually funded here since 2001 following previous 1994-2001 award for REACH Protocol) B Friedman, MD (PI) Pediatrics/Division of Adolescent Medicine Youth 13-24 y/o with HIV infection or attributes (numerous therapeutic, behavioral, and community studies that continuously are introduced, implemented and completed). No drug or treatment protocols are open presently. clinical Trial International Maternal Pediatric Adolescent AIDS Clinical Trials Group Charles Mitchell, Microbiology and Immunology, Pediatrics U01 clinical Trial HIV/AIDS Clinical Therapeutic and Vaccine Trial Unit Medicine NIAID clinical Trial Atherosclerotic Risk and Response to Exercise Intervention in HIV+ Children Tracie L. Miller Pediatrics NHLBI clinical Trial DIETARY INTAKES AND PATTERNS, BIOMARKERS, AND MATERNAL AND INFANT OUTCOMES IN HIV Tracie L. Miller Pediatrics NICHD clinical Trial Pediatric Perinatal HIV/AIDS Clinical Trails Unit Gwendolyn B. Scott Pediatrics NIAID clinical Trial Node of the Drug Abuse Clinic Trials Network Jose Szapocznik Epidemiology & Pub. Health Med. NIDA clinical Trial of Core Site Juan Carlos Ramos Therapeutics Research NCI clinical Trial NIAID IRAC: combination influenza treatment in high risk and low risk patients with acute influenza Hector Bolivar Michelle Morris Therapeutics Research NIAID
ARNP, Kenneth Kavanagh, ARNP (Co-Investigators) Clinical Trial U01 HD040497-06 NIH, Adolescent Trials Network Patricia Emmanuel, MD (PI), Diane Straub, MD, , MD, , MD, Jorge Lujan, MD, Alicia Marion, ARNP, Kenneth Kavanagh, ARNP (Co-Investigators) Pediatric Infectious Diseases ATN is a national, multicenter research network, to conduct research to explore behavioral, microbicidal, prophylactic, therapeutic, and vaccine modalities in and HIV at-risk adolescents, age 12 through 24 Clinical Trial Changes in the B cell repertoire following vaccination with novel H1N1 inactivated influenza vaccine in immune deficient adolescents and young adults chronically infected with HIV , (PI), , MD, , PhD, Maureen Goodenow, PhD Pediatric Infectious Diseases, Allergy and Immunology (USF) and Pathology (UF) Immunologic responses to H1N1 inactivated influenza vaccine in HIV-infected adolescents and young adults Clinical Trial Treatment De-intensification and Residual HIV-1 in Youth. (ATN 081) Allergy and Immunology, USF Effects of early treatment followed by treatment deintensification. Sponsor: NICHD Clinical Trial Preservation & Expansion of Subsets Following HAART De-intensification to Atazanavir/ritonavir (ATN 061) Allergy and Immunology, USF Early treatment of HIV during deintensification to ATV/r. Sponsor: NICHD Clinical Trial Longitudinal changes in cardiovascular risk markers among adolescents newly infected with HIV (ATN 083) Allergy and Immunology, USF Cardiovascular risks in HIV-infected adolescents. Sponsor: NICHD Clinical Trial Assessment of inflammatory Markets Associated with Neurocognitive impairment in HIV-infected Adolescents (ATN 101) Allergy and Immunology, USF Neurocognitive impairment in HIV. Sponsor: NICHD Clinical Trial A randomized placebo trial of probiotics to lower microbial translocation & immune activation in Allergy and Immunology, USF LPS levels and immunity preservation. Sponsor: NICHD
Infant Survival Everywhere) (recruiting) Clinical Trial IMPAACT 1058A: Intensive Pharmacokinetic Studies of New Classes of Antiretroviral Drug combinations in Children, Adolescents and Young Adults (recruiting) , MD CFAP Research Pharmacokinetics of Newer Agents in Children/Youth. Clinical Trial IMPAACT 1066: A Phase I/II, Multicenter, Open-Label, Noncomparative Study of the International Maternal, Pediatric, Adolescent AIDS Clinical Trials (IMPAACT) Group to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiretroviral Activity of Raltegravir (MK-0518) in HIV-1 Infected Children and Adolescents (recruiting) , MD CFAP Research Raltegravir in Children Pharmacokinetics Clinical Trial IMPAACT A5240: A Phase II Study to Evaluate the Immunogenicity and Safety of a Quadrivalent Human Papillomavirus Vaccine in HIV-1 Infected Females (recruiting) , MD CFAP Research HPV in Adult HIV positive females Clinical Trial IMPAACT A5241: The Optimized Treatment that Includes or Omits NRTIs (OPTIONS) Trial: A Randomized Strategy Study for HIV-1 Infected Subjects Using the cPss to Select an Effective Regimen (recruiting) , MD CFAP Research Salvage Antiretroviral Therapy (ART) Treatment-
Behavioral/epidemiological studies Presenter: Alexander M. Cole, Ph.D. Behavioral/Epidemiological HIV Prevention for Criminal Justice-involved Individuals (grant through Nehemiah Educational & Economic Development, Inc.) Roberto Potter, Ph.D. Clinical Justice HIV Prevention NOVA SOUTHEASTERN UNIVERSITY – 4 Studies Presenter: , Ph.D. Behavioral/Epidemiological Cyber Mentors: A Sustainable Model for Developing Minority HIV Researchers Maria Isabel Fernandez, Ph.D. John Anderson, Ph.D. College of Osteopathic Medicine Mentoring and faculty development in HIV prevention Behavioral/Epidemiological Proyecto SOL: A Risk Reduction Intervention for Hispanic MSM Recently Completed Maria Isabel Fernandez, Ph.D.; G. Stephen Bowen, M.D., M.P.H. College of Osteopathic Medicine HIV prevention among Latino/Hispanic MSM Behavioral/Epidemiological Understanding the Scope and Magnitude of Prescription Drug Diversion Steven P. Kurtz, Theodore J. Cicero, Hilary L. Surratt Division of Applied Interdisciplinary Studies HIV, drug use, diversion National Institute on Drug Abuse Grant # DA021330 Behavioral/Epidemiological The Diversion of Antiretroviral Medications to Street Markets Hilary L. Surratt, Gladys Ibanez, Steven P. Kurtz Division of Applied Interdisciplinary Studies HIV, diversion, ARV medications, drug use National Institute on Drug Abuse Grant # DA023157 Presenter: , Ph.D., L.C.S.W. – 11 Studies Behavioral/Epidemiological Promoting Male Involvement to Improve Prevention of Transmission Uptake and Reduce Antenatal Infection Deborah Jones (PI), Karl Peltzer, Stephen Weiss, Olga Villar. Psychiatry Micro and Immunol. HIV and women. Behavioral/Epidemiological Expression and impact of Rutledge, S.E., and Abell, N., College of Social Work HIV/AIDS Provider Stigma; International
Clinical Trial Behavioral/Epidemiological CTN 0049: Project HOPE: Hospital Visit is an for Prevention and Engagement , PI NIDA Clinical Trials Network (CTN) Behavioral/Epidemiological CTN 0047: SMART ED SBIRT* in the Emergency Dept. *screening, brief interventions, referral and treatment NIDA Clinical Trials Network (CTN) DUVAL COUNTY HEALTH DEPARTMENT Presenter: M. Maximillion Wilson, Ph.D. – 2 Studies Behavioral/Epidemiological The Interdiction Project M. Maximillion Wilson, Ph.D. (PI), Samuel Frimpong, M.D., M.P.H. (co-PI) Prevention Unit, Area 4 AIDS Program Office Behavioral Intervention, Behavioral/Epidemiological HIV Mapping: Understanding Service Gaps through use of GIS M. Maximillion Wilson, Ph.D. (PI), David L. Andress Prevention Unit, Area 4 AIDS Program Office. Public Health Program Evaluation – 17 Studies Presenter: John W. Sleasman, M.D. Behavioral/Epidemiological Novel dissemination of a group intervention for HIV+ women via web conferencing Marhefka, Stephanie (PI) Baldwin, Julie Buhi, Eric Community and Family Health Behavioral Science, HIV+ Women, Prevention, MTCT Intervention Dissemination Sponsor: NIMH Behavioral/Epidemiological Florida/Carribean AIDS Education and Jeff Beal Mental Health Law & Policy Provider training, Educational materials Behavioral/Epidemiological Perinatal HIV Transmission Prevention Project Michael Knox (PI) Mental Health Law & Policy Provider training, Educational materials Behavioral/Epidemiological Environmental Factors in HIV Transmission Among Suburban IDUs Wilson Palacios (PI) Criminology Prevention, IVDU Positives
Behavioral/Epidemiological A Randomized Trial of Family-Based HIV Prevention for Latino Youth Celia Lescano (PI) Mental Health Law & Policy prevention intervention, Latinos, disparities Behavioral/Epidemiological Evaluation of Kathleen Moore (PI) Behavioral/Epidemiological Medication Assisted Drug Court Treatment (MADCT) Program Kathleen Moore (PI) Behavioral/Epidemiological New Faculty Recruitment to Enhance Co-Morbidity Research in Justice Settings Roger Peters (PI) Behavioral/Epidemiological Conference: Advances in Translational Research in AIDS/HIV in Shyam Mohapatra (PI) Internal Medicine basic and translational research in HIV; collaborative projects Behavioral/Epidemiological ATN 096: Identifying Undiagnosed Asymptomatic HIV Infection in Hispanic/Latino Adolescents and Young Adults Diane Straub and Patricia Emmanuel Pediatrics HIV testing, linkage to care, Latino Behavioral/Epidemiological Program in Adolescent HIV/AIDS Research Training (PAHRT) – Fogarty AITRP Patricia Emmanuel (PI) Pediatrics prevention, treatment and natural history studies in Gujurat Behavioral/Epidemiological Ryan White Care Act Title IV Adolescent Initiative Patricia Emmanuel (PI) Pediatrics HIV testing, outreach and care for youth Behavioral/Epidemiological Brief Intervention for Drug Use and HIV/STD Risk Prevention Among Truants Richard Dembo (PI) Prevention; Drug Use Behavioral/Epidemiological Statistical Methods for HIV Dynamic Modeling and Design Brian Giunta (PI) Psychiatry and Neurosciences Behavioral/Epidemiological Statistical Methods for Yangxin Huang (PI)
in Men (HIM) Study Cancer Center, Maureen Goodenow (Co-PI), Li, Yin (Co-I) Behavioral/Epidemiological Smoking cessation and the natural history of HIV-Induced Emphysema Thomas Clanton (PI) Exercise and Sports Sciences Pathogenesis Behavioral/Epidemiological A breath-based medication adherence monitoring system for HIV-AIDS therapies (specific AIM2-Food Interference) Timothy Morey (PI), Donn M. Dennis (Co-PI), Susan P. McGorray (PI) Anesthesiology Health Outcomes and Policy Adherence Behavioral/Epidemiological Multiple behavior SBIRT Model of drug abuse among emerging adults in primary Dennis Thombs (PI) Behavioral Science and Comm Health Drug Abuse Behavioral/Epidemiological Florida AIDS Education Training Centers Robert M. Lawrence (PI), Charles E. Stewart (CO-PI) Pediatrics Education Behavioral/Epidemiological HIV risk among racially-diverse, minority youth and partner selection Stephanie Staras (PI) Medicine Behavior Behavioral/Epidemiological Pharmacotherapy for Hazardous Drinking in HIV-infected women (PI), Bridgett Mobeen Rathore, WHAT-IF study investigators Epidemiology, Medicine, Peds, Social & Behavioral Health Sciences Alcohol and HIV Randomized clinical trial Behavioral/Epidemiological Molecular epidemiology of HIV infection in Morocco (PI), , Andy Tatem, Maureen Goodenow, Glenn Morris, Moroccan Epidemiology Pathology Geography Contextual and behavioral factors associated with HIV spread FLORIDA INTERNATIONAL UNIVERSITY – 35 Studies Presenter: , Ph.D. Behavioral/Epidemiological The Impact of HIV/AIDS among Latina/o Suicide Victims (completed) Dr. Ramiro Martinez (PI) HIV/AIDS and Latina/o Suicide Victims Funding Source: NIMHD
socioeconomic status between the time of AIDS diagnosis and death To compare the degree of community racial segregation between the time of AIDS diagnosis and death To characterize patterns and predictors of rural to urban migration between AIDS diagnosis and death Funded by The NCMHHD Trajectories of Drug Abuse and HIV Risk among Latino Father-Son Dyads (Planned) (PI), Frank Dillon, Patria Rojas CRUSADA Substance abuse, HIV/AIDS, health disparities, Latino men Funding Source: NINR Behavioral/Epidemiological Serotonin and Brain Derived Neurotrophic Factor Roles on HIV Risk Behaviors on Latino Dyads (Planned) Investigators: Maria Jose Miguez (PI), , Robert Malow, Patria Rojas, Changwon Yoo CRUSADA Serotonin and Brain Derived Neurotrophic, HIV Risk Behaviors, Latino Dyads Funding Source: NINR Behavioral/Epidemiological Alcohol Use and the in HIV (Planned) Maria Jose Miguez (PI), Deshratan Asthana, Ximena Burbano, , Mehmet Dorak Alcohol Use, Immune-Cardiovascular-Brain , HIV Positives Funding Source: NIAAA Behavioral/Epidemiological Development of an Intervention Package to Reduce Alcohol and Sexual Risks (Planned) Robert Malow (PI), Maria Jose Miguez, Alcohol Use, Immune-Cardiovascular-Brain , HIV Positives Funding Source: NIAAA Behavioral/Epidemiological Multi-level HIV Prevention for Pregnant Drug Abusers Robert Malow (PI), , Michele Jean-Gilles, Brenda Lerner, of Public Health and Social Work This study of Pregnant Drug Abusers in treatment is a randomized trial of Enhanced- Behavioral Skills Training compared to a time- and Health Promotion Comparison (HPC) condition. It responds to the NIH priority on translational research to adapt effective research-based intervention strategies to 'real world' conditions. If successful, this research will offer a realizable HIV intervention strategy, matched
Behavioral/Epidemiological Tanzanian Drug Treatment as AIDS Prevention - Reliability and Validity Study (PI) of Public Health and Social Work To develop culturally appropriate measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment To assess IDUs' understanding and relevancy of the measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment To test the reliability and validity of the Questionnaire Funded by NIDA Behavioral/Epidemiological HIV Risk Behavior and Substance Abuse among Recent Latino Immigrants (PI), Patria Rojas of Public Health and Social Work To study HIV Risk Behaviors and Substance Abuse in recent Latino Immigrants Funded by NCMHD Behavioral/Epidemiological Community Mobilization for HIV Prevention—Racial and Ethnic Approaches to Community Health (REACH) 2010 in . William W. Darrow, PI and Project Leader of Public Health and Social Work (Recently Completed Studies) Eliminate disparities in HIV infection among Black and Hispanic 18-39 year-old residents of 12 high AIDS-prevalence areas of ; Funded by CDC Behavioral/Epidemiological The Impact of HIV/AIDS among Latina/o Suicide Victims Dr. Ramiro Martinez (PI) (Recently Completed Studies) HIV/AIDS and Latina/o Suicide Victims. Funded by NCMHD Behavioral/Epidemiological HIV and Substance Abuse Risk Behaviors Among Hispanic Youth of Dr. WayWay M. Hlaing (PI) of Public Health and Social Work (Recently Completed Studies) HIV, Substance Abuse, Risk Behaviors, and Hispanic Youth of Funded by NCMHD Behavioral/Epidemiological Impact of 2005 Hurricane Season on HIV/ AIDS Health Services in Sukumar Ganapati of Public Health and Social Work (Recently Completed Studies) 2005 Hurricane Season, HIV/ AIDS, and Health Services in Funded by NCMHD Behavioral/Epidemiological : Women Study (PI), Dr. Patria Rojas of Public Health and Social Work (Recently Completed Studies) Intergenerational transmission of drug use, Risky sexual behaviors, Latino women (mother-daughter dyads). Funded by NIDA
Basic Science – 4 Studies Presenter: Alexander M. Cole, Ph.D. Basic Science/Virology Retrocyclins: circular defensins active against HIV-1 (NIH R01 grant AI052017) Alexander M. Cole, Ph.D. (PI) Microbiology and Molecular Biology Topical microbicides to prevent HIV-1 transmission Basic Science/Virology Project 2. Development of as an intravaginal topical microbicide. (NIH U19 grant AI082623) Alexander M. Cole, Ph.D. (PD of Project 2); Phalguni Gupta, Ph.D. (PI; PD of Project 3; U. Pitt); other project and core directors Microbiology and Molecular Biology Topical microbicides to prevent HIV-1 transmission Basic Science/Virology Aminoglycoside microbicides restore natural anti-HIV-1 retrocyclins (NIH R21 grant AI082693) Alexander M. Cole, Ph.D. (PI) Microbiology and Molecular Biology Innate host defense against HIV-1 Basic Science/Virology Reawakening retrocyclins to prevent mucosal STIs (Gates Grand Challenges Explorations Award) Alexander M. Cole, Ph.D. (PI) Microbiology and Molecular Biology Innate host defense against STIs, including HIV – 36 Studies Presenter: , M.D. Basic Science/Virology Targeted siRNA delivery as an anti-HIV microbicide Dr. John T. Macdonald Foundation Department of Human Genetics and the Department of Microbiology and Immunology Microbicide development Behavioral/Epidemiological Basic Science/Virology Longitudinal analysis of a high risk HIV negative cohort (Human Genetics, Microbiology and Immunology, DCFAR), (Epidemiology and Public Human Genetics, Microbiology and Immunology, Epidemiology and Public Genetics and Genomics of HIV infection, Acute HIV infection (AHI)
macrophage reservoirs using agents that promote macrophage apoptosis Basic Science/Virology HIV Exposed Uninfected: Adaptive Immunity , , Microbiology and Immunology, Medicine, VGTI Pathogenesis, Mucosal Immunity Basic Science/Virology UM Developmental Center For AIDS Research Int'l AIDS Malignancy Initiative Program Enrique Mesri Microbiology and Immunology NCI Basic Science/Virology DCFAR- SCCC International Collaborations in AIDS- Malignancies Enrique Mesri, Gail Juan Carlos Ramos Microbiology and Immunology, Medicine, Pediatrics AIDS Malignancies Projects in and NIH Basic Science/Virology International Maternal Pediatric Adolescents AIDS Clinical Trails Group Immunology Laboratory , Microbiology and Immunology NIAID Basic Science/Virology Role of IL21 in HIV infection Microbiology and Immunology NIAID Basic Science/Virology Effect of Raltegravir on immune activation, immune reconstitution and gut microbial translocation in patients with chronic HIV infection Microbiology and Immunology Merck Basic Science/Virology Induction of mucosal SIV immunity in non human primates by secreted Hsp-Gp96 Eckhard Podack, Microbiology and Immunology NIAID Basic Science/Virology HIV Exposed Uninfected: Innate Immunology , Margaret Fischl, Microbiology and Immunology, Medicine, VGTI Pathogenesis, Mucosal Immunity Basic Science/Virology Targeted therapy for Burkitt Lymphoma in Resource Poor Settings Barber Glen Medicine NCI Basic Science/Virology Targeting of EBV Latency in Burkitt's Lymphoma Juan Carlos Ramos Medicine NCI Basic Science/Virology Biochemical Mechanisms of Drug Resistance in HIV RT Walter A. Scott Biochemistry & Molecular Biology NIAID
Antiretroviral Therapy while Monitoring Changes in Markers of Immune Activation among HIV-1 Infected Individuals Without Adequate Immune Restoration. (35835) Basic Science/Virology 140 - Clinical Evaluation of the Xpert® CT/NG Assay New – enrolling soon Medicine Efficacy Basic Science/Virology 73B - Evaluation of the Xpert® CT/NG Assay New Enrolling soon Medicine Efficacy Basic Science/Virology Effect of Raltegravir on immune activation, immune reconstitution and gut microbial translocation in patients with chronic HIV infection Industry Studies Immune reconstitution – 13 Studies Presenter: John W. Sleasman, M.D. Basic Science/Virology R01 AI47723-04A1; NIAID. Impact of HIV-1 Genotype on Therapy Response in Children , MD (PI), , , Soichi Haraguchi, PhD, Patricia Emmanuel, MD Allergy and Immunology Impact of HIV resistance in immunologic and viral responses in HIV-1 infected children and adolescents Basic Science/Virology Defective immunoglobulin somatic hypermutation results in pneumococcal vaccination hyporesponsiveness in HIV infected children. Center for Florida AIDS Research , MD (PI), , MD, , PhD, Maureen Goodenow, PhD. Pediatric Infectious Diseases, Allergy and Immunology (USF) and Pathology (UF) Impact of HIV infection on B cell repertoire and somatic mutation and the role of vaccine response Basic Science/Virology Do children with HIV have disregulated amyloid loads in their blood? Brian Giunta, MD (PI), , , Patricia Emmanuel, MD, , MD, Jaime Fernandez, MD, Frank Fernandez, MD Psychiatry and Pediatric Infectious Diseases Changing levels of amyloid beta in peripheral blood and HIV viral infection. Basic/translational, immune response
Basic Science/Virology Combination of CCR5 32 and SIRNAS targeting HIV Lung-Ji Chang Molecular Genetics & Micro Gene Therapy Basic Science/Virology Analysis of HIV sequence data (PI) Pathology Molecular Epidemiology Basic Science/Virology Foamy virus vector for Immunodeficiency viruses therapy Ayalew Mergia (PI) Pathobiology Gene Therapy Basic Science/Virology Protective CMI mechanisms of a dual subtype FIV Vaccine Janet K. Yamamoto (PI) Pathobiology Vaccine STATE BUREAU OF LABORATORIES – 5 Studies Presenter: Bennett, M.P.H. Basic Science/Virology (Planned) Implementation of a 4th Generation HIV-1/2 Ag/Ab Screening assay and a Confirmatory Process B. Bennett (PI), D. Willis, M. Salfinger, M. Diamante Retrovirology, & Laboratory/Patient Care – HIV-1 acute infection detection and the implementation of a new HIV diagnostic algorithm Basic Science/Virology Correlation on the Use of a Reactive Signal to Cutoff Threshold Value in a 3rd Generation HIV-1/2 Antibody Immunoassay to Expedite Supplemental Testing and Reduce Screening Costs. Poster, 2010 HIV Diagnostic Conference, March 2010, Orlando Bennett B (PI), Fordan S, Diamante M, et.al. Retrovirology, & Laboratory Basic Science/Virology Performance of the Aptima RNA Qualitative Assay with 16- and 32-Member Specimen Pools. Journal of Clinical Microbiology, Vol. 48, No. 9, Sept. 2010, p. 3343-3345 Ethridge S (PI), Bennett, B, Stephens, P, et.al. Retrovirology, & ; CDC and NYDOH LABORATORY Laboratory Basic Science/Virology Cost-Effectiveness of Pooled Nucleic Acid Amplification Testing for Acute HIV Infection after Third-Generation HIV Antibody Screening and Rapid Hutchinson A (PI), Bennett B, et.al. Retrovirology, & ; CDC and NYDOH LABORATORY Laboratory