treatments to expand technological advances within the dynamic field of reproductive endocrinology and infertility. Fertility preservation for cancer patients remains a mainstream option for patients. Elective oocyte freezing for individuals who wish to delay childbearing has relatively recently been removed from the research category by the American Society for Reproductive Medicine (ASRM) and is no longer considered experimental. In our experience, this program has significantly increased over the past year. The IVF Program achieved statistics of clinical pregnancy rates approaching 50% (47.5%) in the less than 35 years/age group. (2016 Society for Assisted Reproductive Technology [SART]). Our program includes a number of patients with decreased ovarian reserve for which many programs will not offer ART/IVF. Provision of such services to this population provides the hope and realistic expectation that they too can achieve pregnancy. The In vitro Fertilization Program remains the largest in the region and serves Western Pennsylvania, Eastern Ohio, West Virginal and Western New York State. CLINICAL PROGRAMS The division continues to expand with respect to depth and breadth of clinical services. The Center for Fertility and Reproductive Endocrinology statistics 2013 2014 2015 2016 New Patients 1677 1467 1386 1905 Return Patients 4155 4191 3653 4420 The division provides clinical application of the most current evidence-based medicine for provision of care in virtually all aspects of Reproductive Endocrinology and Infertility. Acupuncture Our certified acupuncturist, Francine Desmone, has expanded the program to include infertility patients, midlife-menopausal, and most recently a gynecological oncology patient sector. The program continues to assist in pain management, stress relief and relaxation techniques including individuals undergoing assisted reproductive technologies/IVF procedures. Over the academic year 532 patients were treated. Fertility Preservation Program in Pittsburgh The Fertility preservation program at Magee-Womens Hospital provides the most comprehensive menu of fertility preservation options for women, men, girls and boys available anywhere in the United States. With expansion of standard of care as well as research options to preserve gametes, embryos and gonadal tissue as well as commitment to local, national and international outreach, the fertility preservation program has more than tripled the volume of
Orwig Reproductive Development from Gonads to Fetuses Federal 192,928 15,466 Peters Metabolics of Treatment Refractory Depression and Suicidal Behavior Foundation 103,216 0 Peters Central Nervous System Methylation in Treatment-Refractory Depression and Suicidal Behavior Foundation 53,000 0 Peters Non-Invasive Diagnosis of Major Depressive Disorders Foundation 17,684 0 Peters The Placental Epigenome Foundation 90,000 0 Peters A Non-Invasive Diagnostic Test For Necrotizing Enterocolitis UPMC Enterprise 1,278,096 133,125 Rajkovic Magee-Womens Basic and Translational Reproductive Health Training Program Federal 332,783 9,417 Rajkovic Transcriptional Regulation of Early Folliculogenesis Federal 271,012 55,628 Rajkovic Genetic Determinants of Female Differentiation Foundation 45,001 0 Rajkovic MED 12 Mutation and Leiomyoma Pathogenesis Industry 41,340 0 Rajkovic Prenatal Genomic Testing Internal Foundation 167,000 0 Roberts PRE-EMPT (Pre-eclampsia, monitoring, Prevention & Treatment) - Supplement Foundation 56,814 6,313 Roberts Grand Challenges Brazil Prematurity Reduction by Preeclampsia Care (PREPARE) Non Federal 55,151 1,984 Rohan Thermostable Vaginal Probiotic Microbicide Federal 17,847 9,085 Rohan A Biorelevant Dissolution Methods for Particulate Dosage Federal 162,423 12,304 Rohan Preparation of Gels with Increased MK-2048 Concentrations Federal 98,669 58,214 Rohan/Dezzutti Griffithsin-Based Rectal Study Core B Federal 224,106 131,302 Sadovsky Vesicle Based Maternal-Placental-Fetal Communication Foundation 90,000 0 Sadovsky Building Interdisciplinary Research Careers in Women's Health in Pittsburgh - Year 14 Federal 491,595 3,106 Sadovsky Extracellular Vesicles and Their ncRNA Cargo as Markers of Trophoblast Injury - Year 2 Federal 673,499 51,942 Sadovsky The Impact of Maternal Placental Fetal Communication on Pregnancy Health Foundation 125,000 0 Sadovsky The Regulatory Code Governing the Placenta Specific Expression of the Chromosome 19 microRNA Cluster Federal 169,937 40,738 Sadovsky Exosome Based Placental Maternal Communication Federal 302,800 31,946 Sadovsky Zika Research Foundation 10,000 0