Printable Resources Using Nanoparticles to Deliver Targeted Chemotherapy Drugs Appendix A: Day 1 – Pre/Post Test Appendix B: Day 1 – Pre/Post Test Answer Key Appendix C: Day 1 – Exit Slip Appendix D: Day 2 – Ranking of Items Appendix E: Day 2 – Ranking of Items Answer Key Appendix F: Day 2 – Nano-Scale Calculations Activity Appendix G: Day 2 – Nano-Scale Calculations Activity Answer Key Appendix H: Day 2 – Calculations Activity (differentiated) Appendix I: Day 2 – Nano-Scale Calculations Activity (diff) Answer Key Appendix J: Day 3 – Guided Nanotechnology Research Questions Appendix K: Day 3 – Guided Nanotechnology Research Questions Answer Key Appendix L: Day 4 – Disease of Cancer Webquest Activity Appendix M: Day 4 – Disease of Cancer Webquest Activity Answer Key Appendix N: Day 5 – The Engineering Design Challenge Appendix O: Day 5 – The Engineering Design Process Appendix P: Day 5 – The Engineering Design Challenge Rubric Appendix Q: Day 5 – The Presentation Rubric Appendix R: Day 5 – The Daily Performance Rubric Appendix S: Additional Resources
Engineering Design Challenge Rubric 4 3 2 1 Targeting of cancer NDDM* successfully attaches to and bound to at least one cancer cell and zero normal cells NDDM successfully attaches to, but may not stay to, at least one cancer cell and zero normal cells NDDM successfully touches at least one cancer cell and only one normal cells NDDM successfully touches at least one cancer cell and two or more normal cells Elimination of cancer cells NDDM causes 100% destruction of at one cancer cell NDDM causes 50-99% destruction of at least one cancer cell NDDM causes minimal damage to at least one cancer cell NDDM causes damage to both cancer and normal cells Materials At least six different materials are chosen based on structure and function of materials At least five different materials are chosen based on structure and function of materials Only 3 different materials are chosen at random, with little thought as to function Only 2 different materials are chosen with no thought as to function Delivery NDDM is easily delivered through a modeled bloodstream to the target organ. All parts of model are accurately labeled. NDDM is delivered through a modeled bloodstream with some difficulty to the target organ. All parts of model are accurately labeled. NDDM is delivered through a modeled bloodstream with major difficulty to an unspecified location. Missing one accurate label on model. NDDM is delivered through a modeled bloodstream with major difficulty to an unspecified location. Missing two or more accurately labels on model. Scale (note: it would be impossible to make a model exactly to scale!) It is clear that NDDM is at least half of the size of the target cells It is clear that NDDM is smaller than target cells NDDM and target cells are about the same size NDDM is larger than target * - Nano-drug delivery mechanism
Presentation or Video Rubric Category 4 Points 3 Points 2 Points 1 Content (see content requirements below) Thoroughly and clearly states the main points and precise details that are described in the instructions. Adequately states the main points and details that are described in the instructions. States most of the main points and details that are described in the instructions. States few main points and details that are described in the instructions. Design & Organization Clearly organized into a logical sequence with no distracting elements or blocks of text. Organized into a logical sequence with no distractions, but is overly wordy Sequence seems out of order, no distractions, and blocks of text evident No logical organization; some digressions. Unclear, confusing. Many distracting elements and blocks of text Performance Effectively delivers audience by making eye contact with audience and adds to text on slide. Make eye contact, but does not add to information provided on slide. Speaks Makes very little eye contact and read off of slide. Uses incomplete sentences. Little or no attempt is made to stay on the topic. Does not consider audience.
Uses voice variation; interesting and vivid to hear. clearly and confidently. Difficult to understand. Preparation Presentation shows detailed preparation with notecards, but does not read off of notecards Presentation shows satisfactory preparation with some information on notecards Presentation some preparation, but no notecards Presentation is lacking in preparation. Teamwork Presentation shows that each person delivered key information and evidence of rehearsal is evident Presentation shows that 75% of the team delivered key information and evidence of rehearsal is evident Presentation shows that 50% of the team delivered key information and evidence of rehearsal is evident Presentation that 25% of the team delivered key information and evidence of rehearsal is evident Content Requirements: At least three pictures of prototype as your team works through the design process (alternatively, a video could be made to document this process)
Performance Rubric CATEGORY 4 3 2 1 Safety The student follows all safety policies. The student fails to follow a safety policy (This results in a “0” for this category) Preparedness Brought all needed materials to class Failed to bring one item needed for the day’s work. Failed to bring more than one item needed for the day’s work. Failed to anything for class. Attitude Never is publicly critical of the project or the work of others. Always has a positive attitude about the task(s). Observed one time to be publicly critical of the project or the work of others. Often has a positive attitude about the task(s). Observed twice to be publicly critical of the project or the work of other members of the group. Usually has a positive attitude about the task(s). Observed more than twice to be publicly critical of the project or the work of other members of the group. Often has a negative attitude about the task(s). Focus on the task Consistently stays focused on the task and what needs to be done. Very self-directed. Observed to be off task once. group members can count on this person. Observed to be off task twice. Other group members must sometimes nag, prod, and remind to keep this person on-task. Observed to be off task more than twice. Lets others do the work. Working with Others Almost always listens to, shares with, and supports the efforts of others. to keep people working well together. Observe 80% of the time listens to, shares, with, and supports the efforts of others. Does not cause "waves" in the group. Observe less than 80% of the time listens to, shares with, and supports the efforts of others, but sometimes is not a good team member. Does not listen to, share with, and support the efforts of others. Often is not a good team player.