zilongwang/ReadingBank huggingface dataset:
Contents How to Use This Booklet 1 Section 1 — Identifying The Equipment At Your UST Facility 3 Section 2 — Release Detection 5 Section 3 — Suspected Or Confirmed Releases 21 Section 4 — Spill And Overfill Protection 24 Section 5 — Corrosion Protection 34 Section 6 — Frequent Walk-Through Inspections 42 Section 7 — For More Information 44
Correct Filling Checklist What To Do Before Your USTs Are Filled Post signs that alert delivery persons to the overfill devices and alarms in use at your facility. Make and record accurate readings for product and water in the tank before fuel delivery. only the quantity of fuel that will fit into 90% of the tank. Remember, the formula for determining the maximum amount of gasoline to order is: (Tank capacity in gallons X 90% ) — Product currently in tank = Maximum amount of fuel to order Example: (10,000 gal X 0.9 ) — 2,000 gal = 7,000 gal maximum amount to order Ensure fuel delivery personnel know the type of overfill device present at the tank and what actions to perform if it activates. For example, use sample sign on page 27 of this chapter. Review and understand the spill response procedures. Verify that your spill bucket is empty, clean, and will contain spills. What To Do While Your USTs Are Being Filled Keep fill locked until the fuel delivery person requests access. Have an accurate tank capacity chart available for the fuel delivery person. The fuel delivery person makes all hook-ups. The person responsible for monitoring the delivery should remain attentive and observe the entire fuel delivery, be prepared to stop the flow of fuel from the truck to the UST at any time, and respond to any unusual condition, leak, or spill which may occur during delivery. Have response supplies readily available for use in case a spill or overfill occurs (see Section 3). Provide safety barriers around the fueling zone. Make sure there is adequate lighting around the fueling zone. What To Do After Your USTs Are Filled Following complete delivery, the fuel delivery person is responsible for disconnecting all hook-ups. Return response kit and safety barriers to proper storage locations. Make and record accurate readings for product and water in the tank after fuel delivery. Verify the amount of fuel received. Make sure fill ports are properly secured. Ensure the spill bucket is free of product and clean up any small spills. Section 5 — Corrosion Protection To prevent leaks, all parts of your UST system that are underground and routinely contain product need to be protected from corrosion. The UST system includes the tank, piping, and ancillary equipment, such as flexible connectors, fittings, and pumps. Unprotected metal
and sheaves: No excessive wear? Alignment and tension OK? 3 mo Hangers and mounting: All secure, in good condition? 3 mo Terminals: Starter and terminal connections OK? 3 mo Drive: No wear on drive shaft? Drive section is aligned? 3 mo Chains and guards: No missing chain links or teeth? Sprocket and chain guards in place? 3 mo tension: Adjust tension. 3 mo Bolts: Tighten mounting bolts. 3 mo Bearings: Repack and lubricate per manufacturer’s instructions. 12 mo Checklist & Action Items (Action items in italics) Y N Actions taken / Notes Freq (possible) Date AIR DISTRIBUTUON AND TERMINAL SYSTEM Ductwork (supply and return) (id # __________________ ) Condition: No odors, noise or vibration? Clean, no obstructions, debris? No signs of moisture/mold, insects or rodents? No noticeable air 1 mo Connections and seals: Tight, no damage or denting? 3 mo Duct lining: No dirt, dampness, mold? No deterioration? 3 mo Fire and detectors and dampers: Condition ok? 3mo Plenum (id # __________________ ) Condition: No odors, unusual sounds, or vibration? Clean, no obstructions, debris? No signs of moisture/mold, insects or rodents? No leaks from supply or exhaust into return? 1 mo Ceiling tiles: seal of all tiles? No stained/damaged tiles indicating high RH or moisture problem? 1 mo Insulation & fireproofing: Condition OK? 3 mo Fire dampers: Open? 3 mo
(Action items in italics) (possible) HVAC and pipes (id # ___________ ) Condition: No unusual noises, vibration? No corrosion or deterioration? Insulation in place, acceptable condition? No water, or gas leaks? circulates with pump when cooled? 1mo Valves and gaskets: Valves open & close OK ? No corrosion or Hand hold not leaking or deteriorating? Inspect/test safety valves & devices. 1 mo Tanks: Expansion and other tanks and receivers operate properly? No leaks or deterioration? 1mo Drains and traps: Drains clean and unobstructed? charged? 1mo Heat and lubrication: No excessive heat or sparking? Lubrication OK? 3 mo Hangers, connectors, fittings: No loose, missing parts in hangers? Fittings and connectors are not deteriorating? 3 mo Couplings: Shaft security, and safety guards of couplings OK? Alignment OK? (If belt coupled, tension and condition.) No uneven wear? 3 mo Impeller: Impeller moving medium through pipe OK?. 3 mo Housing: Packing, seals, gaskets OK? No leaks?. 3 mo Checklist & Action (Action items in italics) Y N Actions taken / Notes Freq (possible) Date HVAC pumps and pipes (id # ___________ ) continued Wiring: No broken, frayed, and loose wiring? 3 mo Pipes: No leaks, corrosion? No loose connections? 3 mo Inspect and perform preventive maintenance on pumps over 1 H.P. 3 mo
Roof: In good condition? No leaks? 3 mo Foundation: Has proper drainage? No moisture penetration or signs of mold? 3 mo Doors and windows: Caulking and weather stripping in good condition? 3 mo Machine Room (Id#__________) Condition: Clean, no unusual noise or odor? Room is ventilated under negative pressure? 1 mo Elevator Shafts (Id#__________) Condition: Dry, clean? Evacuating odors? 1 mo Stairwells (Id#__________) Condition: Dry, clean, no odors? Doors close and latch? No penetrations allowing uncontrolled air flow? 1 mo
On the Radar 315 20 March 2017 On the Radar is a summary of some of the recent publications in the areas of safety and quality in health care. Inclusion in this document is not an endorsement or recommendation of any publication or provider. Access to particular documents may depend on whether they are Open Access or not, and/or your individual or institutional access to subscription sites/services. Material that may require subscription is included as it is considered relevant. On the is available online, via email or as a PDF or Word document from If you would like to receive On the Radar via email, you can subscribe on our website or by emailing us at H. You can also send feedback and comments to H. For information about the Commission and its programs and publications, please visit You can also follow us on Twitter @ACSQHC. On the Editor: Dr Niall Johnson Contributors: Niall Johnson, Alice Bhasale Reports The Economics of Patient Safety : Strengthening a value-based approach to reducing patient harm at national level Slawomiriski L, Auraaen A, Klazinga N OECD Publishing; 2017. p. 65. URL Notes This OECD-authored report was prepared for a workshop at the Second Global Ministerial Summit on Patient Safety to be held in Germany this month. The report focuses on the economics of patient safety and has two major sections: The cost of failure. Estimating the costs of lapses in patient safety. Reducing harm effectively and efficiently. Exploring a value-based approach to investing in patient safety in a resource-constrained context. The relative costs and impact of various interventions (and combinations thereof) targeting patient harm across healthcare systems are estimated using a snapshot survey of international patient safety experts and policy makers. The key messages from this report include: Patient safety is a critical policy Patient harm is estimated to be the 14th leading cause of the global disease burden. The cost to patients, healthcare systems and societies is considerable. Patient harm imparts a high financial cost. Overall, the available evidence suggests that 15% of hospital expenditure and activity in OECD countries can be attributed to treating safety failures. Patient harm is felt in the broader economy through lost capacity and productivity of patients and carers. It is estimated that the aggregate costs amount to trillions of dollars each year. Most of the burden is associated with a few common adverse events. The most burdensome include healthcare-associated infections (HAI), venous
Online resources Caring for Cognitive Impairment campaign website The updated Caring for Cognitive Impairment campaign website has been released by the Australian Commission on Safety and Quality in Health Care. The Caring for Cognitive Impairment campaign is about providing better outcomes and experiences for patients with cognitive impairment in hospitals, and for their loved ones and staff who care for them. By improving our knowledge and care practices, we can reduce the risk of harm in hospital. The campaign website has a wealth of information, tools, stories and resources aimed at those working in hospitals caring for people with cognitive impairment. The website will also help hospitals prepare for the new cognitive impairment items in the National Safety and Quality Health Service Standards (second edition). See Anyone interested in cognitive impairment are encouraged to commit to caring for cognitive impairment. There is a role for everyone: people living with cognitive impairment, carers, family members and other support people, doctors, nurses, allied health professionals, health service managers, and care and support staff. Medical Devices Safety Update Volume 5, Number 6, November 2017 The Therapeutic Goods Administration (TGA) has released the latest edition of its medical device safety bulletin. Topics covered in this issue include: Button battery safety – TGA has contacted 175 medical device sponsors regarding potential safety issues associated with the use of button batteries Patient education for infusor use – a range of factors can influence the infusion and flow rates encountered when using elastometric infusors Gas cylinder pressure regulators warning – the industry body covering hospital gas suppliers has warned an issue with some gas cylinder pressure regulators Recent safety alerts – TGA safety alerts relating to medical devices published since the last edition of Medical Devices Safety Update. National Stroke Audit The Stroke Foundation has released the 2017 Acute Stroke Audit, which measures the delivery and adherence to evidence-based care outlined in the Stroke Foundation’s Clinical Guidelines for Stroke Management and the Australian Commission on Safety and Quality in Health Care’s Acute Stroke Clinical Care Standard. Clinicians, healthcare administrators and governments can use the data in this report to review services and clinical care in order to improve the quality of stroke management across Australia. For more information on the Commission’s work on clinical care standards, including the Acute Stroke Clinical Care Standard, see
What is your relationship to the victim? 22. Apart from English, is there another language you would like us to use when communicating with you? 23. A person may deem themselves vulnerable if they are unable to take care or protect themselves or others from harm or exploitation. - Would the victim consider themselves as vulnerable? If yes, please provide a brief summary of the vulnerability: 24. Victim Support Services (VSS) provide free and confidential information, support, practical help and advice to victims and witnesses of crime, their families and friends, regardless of when it happened. They also work closely with a wide range of organisations and if a victim/witness needs specialist help that they can’t provide they will contact them to organise the support they need. Victim Support Services offers: Staff and volunteers who are trained to listen, give information and feedback Emotional support similar to counselling, helping people to cope and move forward after a crime Practical help such as completing application forms for criminal injuries compensation and insurance forms. Assistance with getting medical treatment, getting re-housed or dealing with the Criminal Justice System over the course of a trial. If you wish to be referred to victim support, please tick
If you decline at this point, and you wish to refer yourself at a later date, you can contact the Freephone Victim Support Help Line on: 0808 168 9111 Please email this report to We will now review this report and be in contact with you in due course. Thank You.
Show more reactions · · 1 · Show more reactions · · 1 · Write a comment... Bottom of Form 3 YEARS AGO TODAY via · I really miss SCruz... ~BbB~ I grew up in a strange town. One of the most pretentious places in the world, I'd say. 9 out of 10 people under 30 are wearing a sweatshirt or shirt at any given time that says "Santa Cruz" on it s... ANNEKAMIA.WORDPRESS.COM Top of Form Comments Daydreaming 4:20 · Show more reactions In adolescence our world is seemingly definable with ease and simplicity... · Show more reactions
Chapters The Chapter widget allows you to display a “table of contents” during the archive period of your Platform 10 webcasts. To advance the webcast, participants simply click on the chapter of interest. If a new chapter is entered as the webcast plays, the associated chapter title is highlighted. Resource List The Resource List widget enables documents, presentations, URLs, podcasts and other content to be added to your webcast. The following content types are supported (maximum size is 25 MBs per file): Microsoft Word (.doc, .docx) PowerPoint presentations (.ppt, .pptx) Excel spreadsheets (.xls, .xlsx) Acrobat documents (.pdf) Podcasts (.mp3) Videos (.mp4) URLs Contact Us The Contact Us widget provides an easy means for viewers to contact to your company. The widget allows an attendee to send an email to the email addresses that you specify. Email a Friend The Email a Friend widget provides an easy means for viewers to share information about your webcast with their friends and colleagues. Image The Image widget allows an image to be added to your Platform 10 webcasting console. The Image widget can be hyperlinked – that is, if it is clicked, it will take the attendee to the associated website. This widget does not have an icon, because it does not appear in the dock of the console. Text The Text widget allows text to be added to the Platform 10 webcasting console. The Text widget can be hyperlinked – that is, if it is clicked, it will take the attendee to the associated website. This widget does not have an icon, because it does not appear in the dock of the console. Survey The Survey widget allows you to survey your webcast audience during a webcast. You can ask multiple choice, true/false, and open-ended questions, and attendees reply directly from within the webcast. Social Media
promote equality of opportunity, and promote good race relations between people of different racial groups The fire service is committed to fair treatment for everyone in Shropshire whether an employee or service user. Shropshire Fire and Rescue Service Monitoring Information You are required to complete the following detachable form to allow the Fire and Rescue Service to monitor its recruitment/equal opportunities policies. The information you provide will be treated in the strictest confidence and will be used only for monitoring purposes; it will not be used in the selection process. The Fire Service is required to record ethnic origin and the sex of people who apply for appointment. Post Applied For Ref No Full Name Date of Do you consider yourself to be a disabled person? YES / NO* (*please delete) If yes please give details Disabled applicants are invited to contact the Human Resources Office at any point during the recruitment process to discuss steps that could be taken to overcome operational difficulties presented by the job, or if any adjustment or special arrangements are required if selected for interview/test. Please delete or x appropriate box as necessary I describe my ethnic/cultural origin as: White or Asian British British Indian English Pakistani Scottish Bangladeshi Welsh Any other Asian background, please state Any please state _______________________ _______________________ or Black British Caribbean Any other white background, please state African
The importers must pay a to the exporter which is at least the minimum price laid down by Fairtrade Labelling Organizations International , and which is in any case higher than the world market price by a fixed amount, the ‘Fairtrade premium’, The packers in Britain must pay a licensing fee of 3% for the use of the The Law and Ethics It is assumed that activities that are, or have been, unlawful under EU or English consumer protection and trade protection legislation are unethical. The fact that the EU laws are agreed unanimously by 28 countries with different legal systems, with different cultures and different political history suggests that there is a shared perception of what is unethical. Most of the offences discussed here have been crimes for centuries, but constant updating of the legislation and blending the national legislation of the EU countries into one code means that in England they may have appeared, possibly under different names, in the Consumer Protection from ‘Unfair Trading’ Regulations 2008, The Business Protection from Misleading Marketing Regulations 2008, the ‘Fraud’ Act 2006, the Trade Description Act 1968, the Theft Act 1968, the Theft Act 1978, The Fair Trading Act 1973, The Control of Misleading Advertisements Regulations 1988, The Business Advertisements (Disclosure) Order 1977, The Control of Misleading Advertisements Regulations 1988, the Consumer Protection Act 1987, the Consumer Transactions (Restriction on Statements) Order 1976, the Consumer Transactions (Restriction on Statements) Order 1976, and so on. The legislation is constantly being updated. This means that some long established offences like deceit may no longer exist, appearing under another name in the latest legislation, and some may have been abolished in the latest legislation. Accordingly, reference to legislation here does not necessarily imply that the legislation is currently in force, nor give any view on
For fear of causing terror to living beings…Let the Bodhisattva who is disciplining him or herself to attain Compassion, refrain from eating ~ Buddha Going vegetarian may be the most effective way to fight global warming. Buddhist practitioners have practiced vegetarianism over the last 2000 years. We are vegetarian with the intention to nourish our compassion towards the animals. Now we also know that we eat vegetarian in order to protect the earth. ~ Thich Nhat Hanh I do not see any reason why animals should be slaughtered to serve as human diet when there are so many substitutes. After all, man can live without meat… In order to satisfy one human stomach, so many lives are taken away. We must promote vegetarianism. It is extremely important ~ H.H. the 14th Dalai Lama Dear friends, It was almost 50 years ago that I stopped eating meat. At the time, I had friends who were vegetarians for purely health concerns and their ideas about a non-meat diet interested me. Following a bout of amoebic dysentery (I was travelling at the time) and not eating solid food for several weeks, I experimented with not eating meat when I resumed eating solid foods. Many people find the transition to non-meat eating difficult, but for me it was never problematic. Once I made the decision, I never turned back and never missed it. I was happy with my choice, physically and ethically. (Disclosure: My father’s business was wholesale meats, as was my grandfathers, great-grandfathers all the way back to butchers in Germany. I grew up eating choice cuts of meat daily and would spend school holidays among a men’s culture of butchers, sharpened knives, cow carcasses hanging from iron hooks in refrigerated rooms, sawdust on one’s shoes and animal fat and blood on one’s white apron. All this was normal to me.) When I entered the Buddhist path several years later, I was already a practicing vegetarian. My first Zen teacher, Phillip Kapleau, was a committed and passionate vegetarian for both health and ethical reasons. While not an article of faith for our Rochester Zen community, many members, perhaps most, followed a vegetarian diet. Meat, fish, poultry and alcohol were never served at the Rochester Zen Center or any
Be available to greet the employee on the first day. Complete any missing forms from the New Employee Processing section of this document. Introduce employee to everyone on the team Tour the office, area, or campus (make sure to point out restrooms, break areas, and emergency exits) Connect the employee with their orientation partner If possible, eat lunch together Provide employee with keys or access card: Send employee to the Lock Shop (SCB 26A) to get a key, if needed. Hours are 8:00-10:00am on Mon/Wed/Fri and 2:30-4:30pm on Tues/Thurs If building access is needed, email OUPD Access Control Office () to activate Review department procedures and standards such as: Mission and values Office meetings, supplies, and equipment Office safety procedures Evacuation process Fire exits Severe weather Emergency Communication System (ECS); see the for more information Expectations for short breaks and/or lunches Tobacco-free campus policy Travel/mileage reimbursement, if applicable
Separation of Clean and Dirty Instruments SAY: In some Hopkins colon infection meetings, staff members talk about implementing a closing set, or a separate instrument tray used when closing the fascia and the skin. But frontline staff didn’t agree. They wanted to build a separate set for anastomoses. Then during bowel operations, they would have a separate set of instruments to use and then dispose of. It was easier for staff to identify the exact point of the anastomosis than when the closing procedures began. Also included are extra suctioning and change of gloves. These practices were self-audited and spread from general surgery to gynecological and pancreas surgeons, because they operate on the bowel. And now it’s standard practice in the operating room, despite no evidence to support it. Based on input from all operating room providers, it was felt to be the best practice. Slide 20 Bringing Emerging Evidence for SSI Prevention to Your Patients SAY: In this section we will review emerging evidence for SSI prevention. This evidence is not a SCIP requirement, but has reasonable evidence to support adding it to your SSI bundles. Slide 21
SUMMARY CHART FOR RECEPTION CHILDREN – Making accurate judgements; ELG version (Please refer to the guidance overleaf) Cohort year _______ Number of children ________ Start of Reception Attainment on Percentage of children working within each ELG Prime Specific CL PD PSED LIT MATH UW EAD Listening & Attention Understanding Speaking Moving & handling Health & Self-care Self-confidence & SA Managing Feeling & B Making relationships Reading Writing Numbers Shape, Space & Meas People & The world Technology Exploring & u M & M Being Imaginative 22 – 36 months 30 – 50 months 40 – 60 months Children working 40 – 60 months End of Reception Attainment at the end of the EYFS Percentage of children working within each ELG EYFSP emerging EYFSP expected EYFSP exceeding Grey; typical development for age.. PSED: Personal, social and emotional development; PD: physical development; CL; communication and language: LIT; literacy: MATH; mathematics: UW; understanding the world: EAD; expressive arts and design. NB assessments should be made using a "best fit" approach. GUIDANCE NOTES FOR THE SUMMARY CHART FOR RECEPTION CHILDREN Keeping an overall summary chart will enable senior leaders to draw together key records and data and consider at the end of the year whether expected progress has been made for the cohort. The chart is intended as an aid to schools in making an overall judgment about where children are in terms of on-entry attainment - then comparing this with an overall summary at the end of the year. This
The safety program for surgery builds on the lessons learned from previous successful statewide efforts to improve culture and reduce healthcare-associated infections, or HAIs, including the Michigan Keystone ICU program. The Michigan Keystone intensive-care unit, or ICU, program was a multifaceted program that included a checklist to help ensure that providers complied with evidence-based recommendations for the prevention of two other common health care-associated infections, CLABSIs and VAP. The results were quite impressive. They achieved a 66 percent reduction in CLABSIs and a 71 percent reduction in VAP in over 100 Michigan intensive care units. . . . And National-Level Highlights SAY: It also builds on the lessons learned from National On the CUSP: Stop BSI program. That program included more than 1,000 ICUs across 44 States and was with a 43 percent reduction in CLABSI rates. While many organizations had been working on reducing CLABSI for years, the number of participating ICUs that achieved zero CLABSI rates for a quarter more than doubled during the program. 15 Positive Impact of CUSP on Michigan ICU Safety Culture SAY: To address the adaptive work, CUSP was used. CUSP is perhaps the best-validated approach to improve teamwork and safety culture on a large scale. In Michigan, CUSP implementation was associated with a dramatic reduction in the number of units that were in the “needs improvement zone” for both teamwork and safety culture. Slide 16 This Improvement Model Works for Surgery SAY: Evidence shows this approach works. Johns Hopkins, for example, has been using this approach with the support of anesthesia, nursing, and surgical leadership. Hopkins asked staff how the next patient will be harmed and what the hospital can do about it. Combined with emerging evidence and local 17
Missing equipment on a cart: Staff developed a checklist to assign responsibility for stocking supplies on the cart. Inconsistent use of Daily Goals Checklist tool during patient rounds: The staff reached consensus regarding the elements of the tool to be applied during rounds. Residents report receiving inaccurate information during rounds: An electronic progress note system was developed to maintain accurate information exchanges on the unit. How Can Your Team Identify Defects? SAY: Here is a list of some ways through which defects can be identified. We’re used to thinking about event reporting systems, liability claims, sentinel events, and mortality and morbidity conferences when we want to identify defects that occur in our clinical areas. The Perioperative Staff Safety Assessment, which is an effective and proactive tool for identifying defects, adds direct communication with frontline providers. Slide 20 PSSA Taps Wisdom of Frontline Providers SAY: The Perioperative Staff Safety Assessment taps into the wisdom and knowledge of frontline providers in the perioperative area and uses that knowledge to guide efforts to improve safety. In leveraging staff member knowledge, the PSSA allows teams to determine risks that have jeopardized or could jeopardize patient safety on a unit. Frontline staff members are the eyes and ears of patient safety. They can list valid improvement opportunities and focus your safety program activities. Slide 21 What Is the PSSA? SAY: The Perioperative Staff Safety Assessment asks providers to complete four questions about the issue of patient safety in their clinical area. This simple tool asks: How will the next patient be harmed? What can we do to prevent that harm? How will the next patient in the operating room get a surgical site infection? What can we do to prevent the surgical site infection? Slide 22
Supplementary Table 1 – List of the top 500 differently expressed genes between wild type and Moz-/- cultures. Table is provided in an attached Microsoft Excel file. Supplementary 2 – List of the top 500 differently expressed genes between wild type and Moz+/- cultures. Table is provided in an attached Microsoft Excel file. Supplementary Table 3 – List of the top 500 differently expressed genes in a dose dependent manner – i.e. genes that are different between wild type and Moz-/- cultures and show intermediate expression in Moz+/- cultures. Table is provided in an attached Microsoft Excel file. Supplementary Table 4 – List of Broad Institute datasets that significantly correlate with the Moz dataset. The list of genes significantly changed in a ‘dose dependent’ manner (Supplementary Table 3) was compared to differentially expressed genes in the datasets provided by the Broad Institute. Table is provided in an attached Microsoft Excel file. Supplementary Figure 6 – Western blot analysis of passage 3 wild type and Moz-/- MEFs grown at 20% O2. Protein levels of senescence marker and mediator p16INK4A were increased as early as passage 3 in Moz-/- MEFs compared to wild type. In contrast, p15INK4B, p21 and p53 levels were unchanged. Treatment with doxorubicin, which induces DNA damage and cell death, is provided as a positive control for p53. These data are consistent with
mRNA levels of Ink4a, Arf and p21 in passage 3 MEFs (Figure 4), and Ink4a and Arf levels in passage 5 MEFs (Figure 1e). n = 4 independent cultures of each genotype. Actin is provided as a loading control. Supplementary Figure 7 – Expression analysis of wild type and Moz-/- MEFs. (a) Moz mRNA was not detected in Moz-/- MEFs (b) Gene expression levels of major regulators of senescence in wild type and Moz-/- MEFs grown at physiological 3% oxygen. mRNA levels of genes encoding major inhibitors of senescence that were decreased in Moz-/- MEFs at 20% O2 (Fig. 5) were also decreased at 3% O2 (here). This suggests that the reduction in mRNA levels of Cdc6, Skp2, Ezh2, Melk, E2f2 and Nsd2 was independent of DNA damage, which is prevalent in MEFs cultured in 20% O2. (c) Ink4b mRNA levels in Ink4a-Arf-/-;Moz-/- cells were not different to controls (d) Ratio of housekeeping genes Hsp90ab1 mRNA to Gapdh mRNA were not different between wild type and Moz-/- cells at 20% O2. n = 4 independent cultures of each genotype. Gene expression levels were standardised to housekeeping genes Hsp90ab1 and Gapdh. Asterisks mark statistically significant differences between wild type and Moz-/- cultures at *p < 0.05, **p < 0.01 and ***p < 0.001. Supplementary Figure 8 – CDC6 overexpression affords a modest growth advantage to Moz-/- MEFs. MEFs were virally infected with a Cdc6-GFP vector and control negative Empty-GFP vector. Infection with a Cdc6-GFP vector lead to a small but statistically significant increase in Moz-/- cells compared to controls. n = 3 independent cultures of each genotype. Asterisks mark statistically significant differences between wild type and Moz-/- cultures at *p < 0.05.
The gene expression was measured with SYBR green quantitative PCR (Takara RR820A). Data analysis Human lung adenocarcinoma and TCGA breast cancer data were obtained from Oncomine database (https://www.oncomine.org). Figure S1. Inhibition of apoptosis cannot suppress lgl-Ras induced cell invasion. (A-D) GFP-labeled clones of cells with indicated genotypes are created in the developing eye-antennal discs. RasV12/lgl-/- induced tumor invasion into the VNC (A’, n=27) was not affected by expressing YkiS168A (B’, n=10), DIAP1 (C’, n=23), or p35 (D’, n=25). (E) A quantification of tumor invasion phenotype in A’-D’ was shown. (F-G) Caspase 3 activation in lgl-Ras tumors (F’) was not significantly affected by dMyc/dMax expression (G’). Figure S2. Myc expression does not increase ptc>scrib-IR induced apoptosis. Fluorescence micrographs of wing pouch regions are shown. Anterior is to the left and dorsal up in all figures. Loss of scirb induced caspase activation (A’) remained unaffected by the expression of dMax, dMyc, dMyc/dMax, cMyc, or cMyc/dMax Crosses were done at 29 ºC. Figure S3. Inhibition of apoptosis cannot suppress ptc>scirb-IR induced cell invasion. Loss of scirb induced cell invasion (A) could not be suppressed by the expression of DIAP1 (B). Crosses were done at 29 ºC. Figure S4. Myc suppresses ectopic Hep induced cell invasion.
H2 Healthy control NA NA Wild-Type H3 Healthy control NA NA Wild-Type H4 Healthy control NA NA Wild-Type † KRAS c.38G>A mutation is not detectable by CUT-PCR, because it is out of target range. For c.38G>A detection, another design of guide RNA is required. NA: not applicable.
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ONCE FOR SCOTLAND DOCTORS AND DENTIST IN TRAINING (JUNIOR DOCTORS) EMPLOYERS RESPONSIBLITY AGREEMENT (ERA) and STANDARD OPERATING PROCEDURES (SOPs) (Verson 3: 23.08.18) ONCE FOR SCOTLAND ERA LEAD EMPLOYER SOP’S AGREED ONCE FOR SCOTLAND STANDARD OPERATING PROCEDURES PAYROLL FINANCE MEDICAL EDUCATION OCCUPATIONAL HEALTH HEALTH & SAFETY STAFF GOVERNANCE NORTH REGION THIS SECTION HAS BEEN AGREED BY THE NATIONAL DDIT PAYROLL, FINANCE AND SSTS GROUP THIS SECTION HAS BEEN AGREED BY THE NATIONAL DDIT PAYROLL, FINANCE AND SSTS THIS SECTION HAS BEEN AGREED BY THE DME GROUP THIS SECTION IS BEING REWRITTEN BY RHONA WAUGH FOLLOWING A MEETING WITH OCCUPATIONAL HEALTH GROUP REPRESENTATIVES THIS SECTION HAS BEEN AGREED BY THE HEALTH AND SAFETY REPRESENTATIVES EAST REGION WEST REGION NES This agreement has been signed off by Chief Executives in all Boards The Standard Operating Procedures are a work in progress DATA SHARING AGREEMENT TEMPLATE CONTRACTs DDiT PROTECTION
ONCE FOR SCOTLAND DOCTORS AND DENTIST IN TRAINING (JUNIOR DOCTORS) EMPLOYERS RESPONSIBLITY AGREEMENT (ERA) and STANDARD OPERATING PROCEDURES (SOPs) (Verson 4: 01.10.2018 ONCE FOR SCOTLAND ERA LEAD EMPLOYER SOP’S AGREED ONCE FOR SCOTLAND STANDARD OPERATING PROCEDURES PAYROLL FINANCE MEDICAL EDUCATION OCCUPATIONAL HEALTH HEALTH & SAFETY GOVERNANCE NORTH REGION THIS SECTION HAS BEEN AGREED BY THE NATIONAL DDIT PAYROLL, FINANCE AND SSTS GROUP THIS SECTION HAS BEEN AGREED BY THE NATIONAL DDIT PAYROLL, FINANCE AND SSTS GROUP THIS SECTION HAS BEEN AGREED BY THE DME GROUP THIS SECTION HAS BEEN REWRITTEN FOLLOWING A MEETING WITH OCCUPATIONAL HEALTH GROUP REPRESENTATIVES THIS SECTION HAS BEEN AGREED BY THE HEALTH AND SAFETY REPRESENTATIVES THIS SECTION HAS BEEN AGREED AND COVERS ALL GOVERNANCE EAST REGION WEST REGION NES This agreement has been signed off by Chief Executives in all Boards The Standard Operating Procedures are a work in progress DATA SHARING AGREEMENT TEMPLATE CONTRACTs DDiT PROTECTION
Tuberculosis Other infections/ inflammations Normal Tissue Others (specify) 20. Equipments: List of important equipments available and functional status. List of important equipment’s for Oncopathology Laboratory Sr. No. Equipment Specification Availability HISTOPATHOLOGY 1. Tissue Processor – Rotary type -2 Double rotor with each basket of 200 cassettes per run 2. Embedding unit – 1 Unique 3- modular system for ergonomical working 3. Hot air oven – 2 one as back up Temperature range – 0-100 degree 4. Microtome – manual -3 one as back up Integral debris tray, organizer storage tray 5. bath – 3, one as back up Electronic temperature control for exact temperature regulation and indication by digital display 6. Semiautomatic H& E stainer – 1 High throughput robotic stainer for multiple staining application 7. Cryostat – Basic modele 2 one as back up 8. Block filing cabinet- 80 Convenient storage and retrieval of paraffin blocks 9. Multi-headed teaching microscope Immunohistochemistry Lab 10. Automated Immunostainer Automatic – Baking, deparaffinization, cell conditioning and staining including IHC,ISH, SISH, Immunoflurescence, multiparameter IHC and titration Grossing Room 11. Grossing work station – 1 Table for High grade stainless steel with continuous air flow in working area 12. Bone and meat cutting machine for larger hard – 1 Cutting table is made of thick stainless steel sheet with special heavy axles for easy and firm movement 13. Bone Saw – 1 Smooth surfaces easy to clean without dirt traps Cytology Availability 14. Cytocentrifuge -
Revision History Date Description Author May 2007 Initial Publication of OncoTraX: Cancer Registry User Manual Christine Beynon June 2015 Revised to reflect current record layout (NAACCR v15) Kathleen Waller This page intentionally left blank for double-sided printing. Table of Contents
the knockdown efficiencies of Nupr1, Sox2, TEADs, Last1/2, p53, Nestin, and Tert siRNAs. Cells were transfected with negative control siRNA, Nupr1 siRNA#1, #2, Sox2 shRNA#1, #2, TEADs siRNA#1, #2, Last1/2 siRNA#1, #2, p53 siRNA#1, #2, Nestin siRNA or Tert siRNA for 24 hrs. (i) Real time PCRs were performed to quantify the overexpression efficiency. Cells were transfected with Empty vector or Nupr1 cDNA plasmid. Total mRNAs were extracted for quantitative analysis by real time PCR. Mean ± s.e.m.; n=3 independent experiments for all subfigures; *p<0.05; **p<0.01; *** p<0.001. Note that in (c), silencing Sox2 had no effects on p53, Nestin, or Tert expression; ns=not statistically significant. Supplementary Table 1. Sequences of primers for real time qPCR. Supplementary Table 2. Sequences of siRNAs or shRNAs.
Rev Binding sites 5 Fwd AGTTCCCCCAGCTGCTAAAT Binding sites 5 Rev ACCCTGGGGAGGACTACACT Binding sites 6 Fwd CAGCAGCGACGACAAGTAAA Binding sites 6 Rev TGCATTACAAAGGTGCTGGA Binding sites 7 Fwd ACAGTGTAGTCCTCCCCAGG Binding sites 7 Rev TTGTCGTCGCTGCTGGATAG ChIP primers for CDH1 promoters CDH1 promoter Fwd GCTAGAGGGTCACCGCGTCTA CDH1 promoter Rev GCTTTGCAGTTCCGACGCCAC PCR primers Sequence ERα Fwd TGCTTCAGGCTACCATTATGGA ERα Rev TGGCTGGACACATATAGTCGTT Slug Fwd AAGCATTTCAACGCCTCCAAA Slug Rev GGATCTCTGGTTGTGGTATGACA LSD1 Fwd GTGCAGTACCTCAGCCCAAAG LSD1 Rev CCGAGCCCAGGGATCAG β-actin Rev AGCGAGCATCCCCCAAAGTT β-actin Fwd GGGCACGAAGGCTCATCATT Note: Fwd, forward; Rev, reverse
Larger Items: Alma Kits – K-12 (El Alma de la Raza Units) **call for packet of info Aquarium, plastic, Lg. Aquarium, plastic, Sm. CPR equipment -- Choking Manikin Resusci Junior Resusci Baby Actar Squadron Cadet Pac Critter Crates -- Mammal Hides Mammal Skulls Animal Signs/Tracks Aging Mule Deer Herptiles Birds/Waterfowl Raptors Aquatic Eco Cycle Kit --Waste Reduction Kit Event-Based Science Kits (8th grade) *First Flight! *Fraud! *Gold Medal! *Oil Spill! *Toxic Leak! Forensic Lab Kit - (8th grade) Models -- Human Torso Skin Cross Section Tooth Cross Section Eye Solar System Pedometers, PE Pak Rock Collection Set -- The Rock Cycle Sedimentary Igneous Metamorphic Star Lab Skeleton, human Telescope, LX200 (Training Required for telescope usage, contact Ray Tshillard) History Kit - (8th
Ratings Definitions Performed without Challenges (P) The targets and critical tasks associated with the core capability were completed in a manner that achieved the objective(s) and did not negatively impact the performance of other activities. Performance of this activity did not contribute to additional health and/or safety risks for the public or for emergency workers, and it was conducted in accordance with applicable plans, policies, procedures, regulations, and laws. Performed with Some Challenges (S) The targets and critical tasks associated with the core capability were completed in a manner that achieved the objective(s) and did not negatively impact the performance of other activities. Performance of this activity did not contribute to additional health and/or safety risks for the public or for emergency workers, and it was conducted in accordance with applicable plans, policies, procedures, regulations, and laws. However, opportunities to enhance effectiveness and/or efficiency were identified. Performed with Challenges (M) The targets and critical tasks associated with the core capability were completed in a manner that achieved the objective(s), but some or all of the following were observed: demonstrated performance had a negative impact on the performance of other activities; contributed to additional health and/or safety risks for the public or for emergency workers; and/or was not conducted in accordance with applicable plans, policies, procedures, regulations, and laws. Unable to be Performed (U) The targets and critical associated with the core capability were not performed in a manner that achieved the objective(s).
REPUBLIC OF NAMIBIA NOT-REPORTABLE HIGH COURT OF NAMIBIA MAIN DIVISION, WINDHOEK JUDGMENT Case no: A 44/2013 In the matter between: ONDONGA TRADITIONAL AUTHORITY APPLICANT and OUKWANYAMA TRADITIONAL AUTHORITY RESPONDENT Neutral citation: Ondonga Traditional Authority v Oukwanyama Traditional Authority (A 44-2013) [2015] NAHCMD 170 (27 July 2015) Coram: MILLER AJ Heard: 18 November 2013 Delivered: 27 July 2015 Flynote: Practice – Parties – Joinder – Necessary parties – Application by a Traditional Authority established by the Traditional Authorities Act 25 of 2000 – Applicant not citing all parties who are necessary parties to the proceeding – Court held that the non-joinder of those statutory bodies is fatal – Court struck the application with costs.
DISINFECTION Treatment Unit No. of Units Manufacturer or Material Dimensions (ft) Volume (gallons) Plan Sheet Reference Specification Reference If chlorination is the proposed method of disinfection, specify detention time provided: minutes (NOTE – 30 minutes minimum required), and indicate what treatment unit chlorine contact occurs: If ultraviolet (UV) light is the proposed method of disinfection, specify the number of banks: , number of lamps per bank: and maximum disinfection capacity: GPM. RESIDUAL TREATMENT Treatment Unit No. of Units Manufacturer or Material Dimensions (ft) Volume (gallons) Plan Sheet Reference Specification Reference WASTEWATER TREATMENT FACILITY DESIGN CRITERIA – (continued): PUMPS Location No. of Pumps Purpose Manufacturer / Type Capacity Plan Sheet Reference Specification Reference GPM TDH BLOWERS Location No. of Blowers Units Served Manufacturer / Type Capacity (CFM) Plan Reference Specification Reference
Please choose the correct operating system to download Citrix. Windows Users : Please click on download. MAC Users: Please click on download now. Please right click to allow the add-on. Click Install and click save to your computer. Now select “Launch” to install the software and confirm “yes” or “Allow” to install successfully After successful installation of Citrix Select the link Enter your supplied user name in the first box and the supplied password in the second box as labeled and hit “Log On”.
Tentative Schedule MONDAY TUESDAY WEDNESDAY THURSDAY FRIDAY 29 Introduce Playwriting Assignment (read example, look at format) Brainstorm scenarios Choose partners Choose scenario 30 Journal Outline basic plot Turn in plot diagram Write brief description of setting 1 Work on character webs and questionnaires DUE TOMORROW 2 Share character webs with partner Discuss who will write which part of the scene 3 DRAFTING Your half of the scene is due Monday, May 13th. Does not have to be typed. 6 TESTING NO CW 7 TESTING No 1st pd CW We will have 6th pd CW 8 TESTING We will have 1st pd CW We will have 6th pd CW (8th grade only) 9 9th Grade TESTING- You will report to the gym instead of my class. Bring something to do!! 10 9th Grade TESTING- You will report to the gym instead of my class. Bring something to do!! 13 Revision with partner Typing/Formatting 14 Typing/Formatting 15 HONORS DAY 9th Grade TESTING- 6th CW will report to gym 16 Share! 17 Share! 20 Share! Celebration of Writing Day! 21 EXAMS 22 23 24 Category Possible Points Points Earned Character: Accurately portrays characters through dialogue 10 points Content: Creative, yet accessible (and plausible) plot line, characters, and setting 10 points Content: Logical flow of events 8 points Content: Substantial length (enough to understand events, characters, and conflict) 5 points Assignment: Included all of the script as outlined on assignment sheet 10 points Format: directions included and are clear (bracketed and italicized throughout script) 8 points Format: Names capitalized (every time!) with colon after 3 points Format: Spacing is correct 3 points Revision: Errors in mechanics do not disrupt the flow of events 5 points Sharing: Each partner puts forth effort when it is your group’s turn to share; each partner has shared the load throughout the project! 8 points Total: ____/70 points
Leestown Middle School 2015 – 2016 Class Period Grade 6 Grade 7 Grade 8 Exploratory 1 10:05 – 10:52 10:05 – 10:52 10:05 – 10:52 10:05 – 10:52 (PLANNING) 2 10:54 – 12:04 [LUNCH] 10:54 – 11:41 10:56 – 11:35 (PLANNING) 8th grade 10:56 – 11:35 3 12:06 – 12:52 11:43 – 12:52 [LUNCH] 11:39 – 12:18 (PLANNING) 8th grade 11:39 – 12:18 4 12:56 – 1:35 (PLANNING) 12:54 – 1:40 12:21 – 1:28 6th 12:56 – 1:35 5 1:39 – 2:18 (PLANNING) 1:42 – 2:28 1:30 – 2:17 6th grade 1:39 – 2:18 6 2:22 – 3:07 2:32 – 3:11 (PLANNING) 2:19 – 3:06 7th grade 2:32 – 3:11 7 3:09 – 3:55 3:15 – 3:55 (PLANNING) 3:08 – 3:55 7th 3:15 – 3:55 Leestown Middle School One Hour 2015-2016 CLASS Line # TIME-IN TIME-OUT Table # SAFE 1 11:00 11:20 In Room
Period 6 Grade 7 Grade 8 Exploratory 1 11:05 – 12:01 [LUNCH] 11:05 – 11:43 11:05 – 11:43 11:05 – 11:43 (PLANNING) 2 12:03 12:40 11:45 – 12:46 11:47 – 12:19 (PLANNING) 8th 11:47 – 12:19 3 12:42 – 1:20 12:48 – 1:24 12:23 – 1:18 (PLANNING) [LUNCH] 8th grade 12:23 – 1:18 [LUNCH] 4 1:24 – 1:56 (PLANNING) 1:26 – 2:04 1:20 – 1:57 6th grade 1:24 – 1:56 5 2:00 – 2:32 (PLANNING) 2:06 – 2:43 1:59 – 2:36 6th grade 2:00 – 2:32 6 2:36 – 3:14 2:47 – 3:19 (PLANNING) 2:38 – 3:15 7th 2:47 – 3:19 7 3:16 – 3:55 3:23 – 3:55 (PLANNING) 3:17 – 3:55 7th grade 3:23 – 3:55 Leestown Middle School Two Hour Delay 2015-2016 CLASS Line # TIME-IN TIME-OUT Table # SAFE 1 11:10 11:30 In Room 6th Herald -Stallions 1 11:10 11:30 1 6th Ross 2 11:10 11:30 8 6th 1 11:14 11:34 10 6th King 2 11:14 11:34 12
11 OCO 2017 Overview: Ombudsman Services (Jan. 1, 2017 to Dec. 2017) # of Individuals # of Contacts Total Number of Inquiries 137 174 Total Number of Complaints 117 164 Total 254 338 Slide 12 OCO 2017 Overview (Feb. 2 to Dec. 31, 2017) Geographic Location of OCO Contacts This is a pie chart depicting the contacts in Eastern, Central, and Western Mass and unknown. Eastern Mass – 207 Central Mass – 68 Western Mass – 53 Unknown – 10 Note: on zip code, which the OCO began collecting in February 2017. Slide 13 2017 Trends (vary by time period) Transportation Months Trend Number of Calls Resolved Jan – Feb Difficulty scheduling transportation 5 Mar – May Rude/late drivers 2 Jul – Dec Members’ reminder calls 3 Dental Months Trend Number of Calls Resolved
One Minute Fluency Probe Record Sheet Name: __________________________________ Age: ____________ Date: ________________ Name of text: _____________________________________ A: Number of read: B: Number of uncorrected errors: A-B= word correct per minute (WCPM) WCPM Guide to words correct per minute: level Words correct per minute 1 80 2 90 3 110 4 140 5 150 6 180 Reference: Rasinski, 1989
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Differentiation Offered All Lessons Monday are Whole Group for Introduction Story Elements: Main Idea below: draw and label the main idea of “One More Friend” On level: Complete Main Idea Level 1 Above: Complete Main Idea Level 2 Focus: Main Idea of “A Perfect Lunch” low: draw and label the main idea on construction paper, read leveled readers, put sight words in correct sentence on level: Main Idea level 1, put sight words in correct sentence above: Main Idea level 2, put sight words in correct sentence Summarizing Closure Activity (20-30 min) Journaling: Who is a good friend to you and why? Exit Slip: Comprehension of story elements (Use for differentiation groups) Journaling: Design your own snowflake and describe it. Thursday 1/08/15 Friday 1/09/15 Additional Notes Focused Standard/Element (s) ELACC1RL3 ELACC1RL5 S1E1a,b,c SS1H1 a, b ELACC1RL3 ELACC1RL5 S1E1a,b,c SS1H1 a, b WIDA Standard ELP Standard 2; 2; Reading, Science, Social Studies ELP Standard 2; Level 2; Reading, Science, Social Studies