Goldberg 2015 RCT (2-arm) No Patients with SMI, MDD, Anxiety Psycho-education focused on nutritional counseling caloric expenditure and portion control and behavioral and motivational self-management strategies including weekly goal setting and regular weigh-ins. Delivered by psychosocial and behavioral interventions with seriously mentally ill adults. Individual sessions 1x/week for 1st month followed by weekly group sessions of ~60 minutes during months 2–4. Months 5 & 6 had 4 biweekly sessions and 2 individual sessions Met once per month w/ research staff to be weighed and receive information about diet and exercise. 53 56 Hoerster 2014 Retrospective Obs without comparison group Yes General, but stratified by PTSD, other MH or no PTSD/MH ‘Intense and Sustained’ MOVE! participation N/A 4589 in PTSD subgroup; 7683 in MH subgroup; 8547 in no MH sub group N/A Jackson 2015 Retrospective Obs with control Yes General ‘Intense and Sustained’ MOVE! participation (at 8 sessions within 6 months with a span of at least 129 days between 1st and last session); ‘Low Intensity’ participation (at least one session without meeting the criteria for intense and sustained participation) No MOVE! participation 19367 sustained participants; 219,173 1,606,257 Janney 2015 Retrospective Obs without control group Yes Pts with sleep disordered breathing Participation in MOVE! of whatever modality and format provided in each VISN 20 facility N/A 84,770 N/A Kahwati, 2011 Retrospective Obs with control group Yes General At 2 treatment visits of MOVE! No MOVE! participation 31,854 71,725 Littman, 2012 Retrospective Obs with control group No General At least 1 MOVE! related encounter (y/n); MOVE! participation intensity (non- participation vs. 1 2 5 and =>6 MOVE! Encounters) No encounter 3,192 73,407 Littman, 2015 Retrospective Obs without control Yes General, but stratified by SMI, major depressive disorder (MDD) or neither SMI or MDD MOVE! of whatever modality and format provided in each VISN 20 facility N/A CHECK Screen SMI group=37889; Keep SMI=27,285; Screen MDD =168,826; Keep Engage SMI=18,192; Weight related
SMI=4,303; Engage DD=100,428 ; Weight DD=30,563; Screen or MDD Keep No SMI or Engage No SMI or DD=146,245 Weight No SMI or DD=22,868 Maciejewski, 2013 Retrospective Obs with control group Yes (126 VAMCs) General Copay waived for MOVE! visits Copay still required Before Copay After Copay 64,398 McVay 2014 Retrospective Obs with control group Yes General Participation in MOVE! No participation in MOVE 12631 32,641 Romanova 2013 Retrospective Obs without control group No General 2-hour nutrition class led by dietitian then up to 8 1-hr weekly multidisciplinary education group sessions led by physicians dietitians physical and recreational therapists and psychologists N/A 377 N/A Rosenberger 2011 Prospective Obs without control No General Each visit series of 30-minute visits with each discipline: Medical Health Psychology Nutrition and Physical Therapy N/A 155 N/A Skoyen 2015 Retrospective Obs without control No General 1 or 2 three months cycles of TELE-MOVE!; TeleMOVE participants received a telehealth monitor a standardized digital scale a pedometer to track steps and a MOVE! handout booklet. Daily for 90 days the monitor delivers 5-min educational modules on the screen that are read aloud. After each module telehealth monitor asks a series of questions and offers multiple-choice answers to select from on the screen N/A 2 cycle group=106; 1 cycle group=65 N/A Spring 2014 Retrospective Obs without controls Yes General MOVE! program however provided at sites N/A 18865 N/A Taft 2011 Prospective Obs without control group No General Multidisciplinary cognitive-behavioral weight-management MOVE!: format of 2 months in which each group session was directed by a registered dietician, a doctoral-level clinical health psychologist, an advanced nurse practitioner and a pre-doctoral psychology intern N/A African American (AA)=154; Non-AA= 82
4. Weight Change Results from Sixteen Studies Author Observation Period Study Population Weight Outcomes Mean Weight Change % with >5% Loss Ahrendt, 2014 12 months General MOVE! = −3.3kg; No MOVE! = +2.0kg - Dahn, 2011 12 months General MOVE! = −1.6kg; ∆ Self Management Support=~0? (p 979& Fig 1) CHECK - Damschroder, 2014 12 months General MOVE!=−1.4kg ASPIRE Group=−2.8kg ASPIRE Phone=−1.4kg - Desouza, 2012 6 months Pts with apathy score > 40 (AES) MOVE!=−1.84kg MOVE!+Methylphenidate=−4.61 ∆ Nutr Couns=−0.6kg - Garvin, 2015 6 months General - All MOVE!= 15.7% High Intensity MOVE! (14+ sessions) = ~25% Garvin & Marion, 2015 Undefined General MOVE! = -2.8lb convert to kg All MOVE!=13% Goldberg, 2013 6 months General (by SMI, MDD, anxiety) ns (∆ of Tx completers not reported) 6% in MOVE! and Control combined Hoerster, 2014 6 and 12 months General (by PTSD, MH or neither) 6 months: PTSD = −2.58kg Other MH =−2.86kg Neither =−3.58kg 12 months: PTSD = −2.4kg Other MH = −2.81kg Neither =−3.58kg 6 months: PTSD = 23.7% Other MH = 25.6% Neither = 28.7% 12 months: PTSD = 27.7% Other MH = 28.0% None = 29.6% Janney, 2015 6 and 12 months General (by SDB) 6 months: SDB = −1.13kg No SDB = −1.5kg; 12 months: SDB = −1.40kg -
No SDB= −1.18kg Kahwati, 2011 6 months General 6 months: MOVE! = -1.63kg Control = -0.45kg If 8+ visits: -3.72kg 18.6% of patients who participated in 2+ visits vs. 12.5% matched control that did not receive any MOVE! Littman, 2012 6 and 12 months General 12 months: MOVE! = -0.59kg Control = 0.13kg If 6+ visits: -1.68kg -- Littman, 2015 6 and 12 months General (by SMI, MDD or Neither) 6 months: SMI = −1.22kg MDD = −1.32kg Neither = −1.68kg 12 months: SMI = −1.59kg MDD = −1.22 Neither = −1.50kg 6 months: SMI = 18.3% MDD = 17% Neither = 18.1% 12 months: SMI = 25.2% MDD = 20.5% Neither = 19.5% Romanova, 2013 12, 24 and 36 months General 12 months: −2.19kg 24 months: −0.95kg >24 months: −0.54kg Rosenberger, 2011 12 months General 12 months: -3.2lbs convert to kg 22% Skoyen, 2015 3 months or 6 months TeleMOVE! 3 months (1 Cycle): = −5.55kg 6 months (2 Cycles): = −11.68kg - Taft, 2011 12 months General (by race) 12 months: AA = −0.59kg Non-AA = −1.36kg - Note: SMI=serious mental illness, PTSD=post-traumatic stress disorder, BPD=bipolar disorder, MDD=major or other depressive disorder, SDB=sleep disordered breathing, AA=African-American, MH=mental health