Membership Committee, 1999 – 2001 Finance Committee, 1999 – 2001 Board of Directors, 1999 – 2001 Publication Committee, 2000 – 2003 Critical Issues Committee, 2002 – 2004 ABC Traveling Fellowship Committee, 2003 – 2006 Emerging Leaders Program Guide, 2004 – 2006 Critical Issues Committee, 2009 – 2012; Committee Chair 2012-present American of Orthopaedic Surgery Director, 2008 – present Written Examination Committee, 2009 – present Orthopaedic Research Education Foundation Board of Trustees, 2003 – 2011 Chair, Grant Writing Workshop, 2006 – 2010 Executive Committee, 2007 – 2011 Secretary, 2007 – 2011 Awards AOA Resident Traveling Research Award, “Differential expression of transforming growth factor-ß receptors and biological effects in maturationally distinct subpopulations of growth plate chondrocytes.” 1988 Kappa Delta Award, Orthopaedic Research and Education Foundation, 1995 The Dane and Mary Louise Miller Endowed Research Grant, Orthopaedic Research and Educational Foundation, 1997
Cristin Ferguson, MD, “The regulation of chondrocyte maturation through SMAD signaling.” 04/99 – 07/00 Alexander Soloviev, PhD, “Mechanisms of activation of NFkB by debris particles and regulation of TNF-alpha in macrophages.” 08/99 – 06/01 Jill-Marie Gelinas, MD, “The role of IL-6 in periprosthetic osteolysis.” 08/01 – 09/02 Michael Darowish, MD, “The role of IL-6 in wear debris mediates osteolysis.” 06/04 – 06/05 Tian-fang Li, MD, “Smad3 regulation of chondrocyte maturation.” 06/02 – 6/06 Yufeng Dong, MD, “Wnt expression and signaling in endochondral bone formation.” 09/02 – 09/07 Jennifer Jonason, PhD, “Mechanisms involved in VEGF regulation by beta-cateinin.” 9/07 – present Calvin Hu, MD, Post doctoral fellow, “The development of a non-union model in murine fracture healing.” 07/08 – 6/09 Sarah Offley, MD, Post doctoral fellow, “The development of a non-union model in murine fracture healing.” 07/09 – 06/10 Kiminori Yukata, PhD, “Intracellular signals regulating stem cell population recruitment and expansion in fracture young and aged bone repair.” 06/09 – 05/11 Zaneb Yaseen, MD, “The development of a non-union model in murine fracture healing.” 07/10 – 06/11 Medical Student Trainee James Hsu, B.A., “Effect of IL-10 on macrophage responses to wear particles” 06/97 – 06/98 Dhruv Pateder, B.S., “Regulation of PTHrP expression by chondrocytes, role of and Smad-mediated signaling.” 6/99 – 6/00 Carmody, B.S., “IL-10 gene therapy prevents wear debris induced bone resorption. 6/00 – 6/01 Ra’Kerry Rahman, B.S., “IL-6 regulation by debris particles and a role in periprosthetic osteolysis.” 6/02 – 6/03 TGF-
Journal of Histochemistry and Cytochemistry Journal of Orthopaedic Research Journal of Orthopaedic Trauma Molecular and Cellular Biology Molecular Therapy Nature Medicine Osteoarthritis and Cartilage Plos One Pediatric Research Spine Tissue Engineering Toxicology and Applied Pharmacology Editorial Boards Journal of Bone and Joint Surgery, Basic Science, 2001 – 2006 Journal of Bone and Mineral Research, 2002 – present Associate Editor - Journal of Bone and Mineral Research, 2008 – 2012 Associate Editor – Bone, 2013 – present Books/Journals Edited Current Opinions in Orthopaedics, Metabolic Bone Disease and Basic Science Edition Editor, 2000 Orthopaedic Knowledge Update 7, Basic Science Section Editor, 2001
“The potential of pharmacologic agents for the inhibition of periprosthetic bone loss and loosening.” Visiting Lecturer, Novartis Pharmaceuticals, Summit, NJ, April 24, 1997 “Bone morphogenetic proteins commit growth plate chondrocytes to maturation.” Invited Participant/Presenter NIH/AAOS Workshop on “Skeletal Morphogenesis in Growth.” Howey-in- the-Hills, FL, May 3-6, 1997 “Bone loss in cancer and in association with joint prostheses.” Grand Rounds, Department of Orthopaedics, University of Rochester, Rochester, NY April 10, 1998 “Periprosthetic loosening: Molecular mechanisms and therapeutic intervention.” University of Bristol, U.K., April 19, 1999 “Molecular mechanisms of bone metastasis: A search for therapeutic intervention.” University of Manchester, U.K., 21, 1999 “Bone morphogenetic proteins are modulators of chondrocyte maturation.” University of Nottingham, U.K., April 26, 1999 “BMP’s stimulate chondrocyte maturation.” Southampton University, U.K. May 5, 1999 “Reconstruction of severe periacetabular metastases restores ambulation and independence.” Perth, Australia, May 9, 1999 “Periprosthetic loosening: Molecular mechanisms and therapeutic intervention.” University of Adelaide, Australia, May 12, 1999 “Reconstruction of severe periacetabular metastases restores ambulation and independence.” Adelaide, Australia, May 13, 1999 “Periprosthetic loosening: Molecular mechanisms and therapeutic intervention.” University of Melbourne, Australia, May 15, 1999 “Mechanisms of periprosthetic loosening.” Christchurch, NZ, May 17, 1999 “Mechanisms of bone metastasis.” Auckland, NZ, May 22, 1999 “Biological mechanisms of prosthetic loosening and potential therapeutic strategies.” Visiting Professor, Johns Hopkins Medical School, Department of Orthopaedics Baltimore, MD, September 30, 1999 “Periprosthetic osteolysis: Signaling pathways and pharmacologic approaches.” 93rd Annual Interurban Orthopaedics Society Meeting, In Symposium, Molecular Biological Approaches to the Prediction and Prevention of Arthroplasty Loosening, Rochester, NY, October 8, 1999
“Chondrocyte Phenotype and Gene Expression and The Pathogenesis of Osteoarthritis”, University of North Carolina, Thurston Arthritis Research Center, Chapel Hill, NC, March 30, 2012 “The Role of Stem Cells and Their Regulation in Bone Repair” West Virginia University, Morgantown, WV, May 11, 2012 “Challenges of Health Reform: Need for Innovation in Musculoskeletal Care” West Virginia University, Morgantown, WV, May 11, 2012 “Use of Complementary Murine Models to Define the Cells, Molecular signals, and Therapeutic Targets to Improve Fracture Healing” AMGEN, Thousand Oaks, CA, May 31, 2012 “Improving Orthopaedic Care Through Translational and Clinical Research: Opportunities and Challenges” Annual Mallory-Coleman Research Day, Ohio State University, OH, June 8, 2012 “The Role of Stem Cells and Their Regulation in Bone Repair” University of Connecticut Health Center, New England Musculoskeletal Institute, Farmington, CT, June 22, 2012 “Healthcare Reform: Changes in the Care Delivery University of Rochester, Rochester, NY, February 7, 2013 “The Integration of TGF-beta and BMP Signaling in Cartilage Through MAP Kinase Signaling”, Orthopaedic Hospital Research Center, University California Los Angeles, CA, March 14, 2013 “Improving Orthopaedic Care Through Translational and Clinical Research: Opportunities and Challenges” University of Carolina, Chapel Hill, NC, May 17, 2013 “U.S. Healthcare and the World: How Do We Compare and Do We Need Change?” University of North Carolina, Chapel Hill, NC, May 17, 2013 “Stem Cell Populations and Signals That Regulate Bone Regeneration” Kobe Convention Center, Kobe, Japan, June 1, 2013 “Stem Cell Populations and Signals That Regulate Bone Regeneration” Rush University, Chicago, Illinois, June 20, 2013 “Bone Tumor – Clinical Progress” Southwest Hospital, Chongqing, China, August 12, 2013 “Bone Tumor – Clinical Progress” Zhejiang University, Hangzhou, China, August 15, 2013
“Symposium 1: Successful Clinician Scientist Business Models.” American Orthopaedic Association 117th Annual Meeting, Boston, MA, June 24, 2004 “Translation: Basic Science to Clinical Application.” Gordon Research Conference, Musculoskeletal Biology and Bioengineering, Andover, NH, July 28, 2004 “Panel reactor (American Academy of Orthopaedic Surgeons).” ACR Annual Meeting, San Antonio, TX, October 18, 2004 “Fracture healing.” ORS/AAOS Annual Meeting, Washington, DC, February 19-25, 2005 “Chondrocyte, Joint and Growth Plate Development land Pathology.” 2006 Research Symposium on Developmental Biology in Orthopaedics, Toronto, Canada, October 26, 2006 “Fracture Healing”, Moderator, Orthopaedic Research Society Annual Meeting, San Diego, CA, February 13, 2007 “Biological Questions in Implant Wear”, Moderator, AAOS/NIH Osteolysis and Implant Wear: Biological, Biomedical Engineering and Surgical Principles, Austin, TX, November 9-11, 2007 “Gene Therapy and Tissue Engineering in Orthopaedic Surgery”, Moderator with Steve Goldstein, PhD and Johnny Huard, MD, AAOS Annual Meeting, San Francisco, CA, March 6, 2008 “Running a Lab.” AAOS / ORS / OREF Clinician Scientist Development Program (CSDP) Quebec City, Canada, June 1-3, 2008 “Paper session: Tumor.” Moderator, AOA/COA Combined Annual Meeting, Quebec City, Canada, June 4-7, 2008 “Genomic Screening Techniques for Disease Susceptibility and New Treatments.” Moderator, 2008 AAOS/ORS Molecular Biology and Therapeutics in Musculoskeletal Oncology Research Symposium Therapeutics in Musculoskeletal Oncology, Research Symposium, Hilton Salt Lake City Center, Salt Lake City, UT, September 25-27, 2008 “Gene Therapy and Tissue Engineering in Orthopaedic Surgery.” Moderator with Steve Goldstein, PhD and Johnny Huard, MD, AAOS Annual Meeting, Las Vegas, NV, February 23, 2009 “Bone Tissue Engineering and Regeneration: From Discovery to the Clinic” with Dr. Jeremy Mao - 2010 TERMIS-NA Pre-Conference Workshop, Lake Buena Vista, Florida, December 4, 2010