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A single center randomized prospective study on the peristaltic direction of gastrointestinal anastomosis **in Roux-en-Y reconstruction**
after distal curative gastrectomy for gastric cancer
(**DJY002 Trail**)
Edition Number: 1.0 Edition Generation Date: Qct 30, 2020 Principal Investigator: Jingyu Deng and Han Liang Research Institute: Cancer Hospital & Institute of Tianjin Medical University
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protocol

- Distal gastric adenocarcinoma (antrum, pylorus, angle, and/or lower part of body) identified by histopathologic examination without non-curative resection factors
- Undergo potentially curative gastrectomy plus lymphadenectomy (cTanyNanyM0)
- Age between 18 and 70 years
- KPS score >60
- No neoadjuvant therapy
- No seriously chronic diseases of important organs - No other malignancies Randomized included in the study Group A(Isoperistaltic anastomosis)  
  
(n=74)
Group B(Antiperistaltic anastomosis)
(n=74)
Undergo curative gastrectomy plus lymphadenectomy Isoperistaltic direction of gastrointestinal  
  
anastomosis in Roux-en-Y reconstruction Antiperistaltic direction of gastrointestinal anastomosis in Roux-en-Y reconstruction  
   
Differences of effects of early recovery  
 postoperatively (exhaust, defecation, eating, residual stomach peristalsis, length of hospital stay, etc.)
Evaluation the a reliable peristaltic direction method of gastrointestinal anastomosis in Roux-en-Y reconstruction for patients in favor of making an important contribution to reduce medical costs and potential improvements of the prognosis after distal curative gastrectomy for gastric cancer.