Clinical trial: NCT04949646
Section: Possible Risks, Discomforts, and Inconveniences
Subsections: 3. Hazards And Adverse Effects

Possible adverse effects include surgery-specific complications such as, recurrence of the disease, oedema, hematoma, infection, urogenital dysfunction, sepsis, ICU admission and death. Nevertheless, providence for the treatment of complications has been included.  
4. **Expected Benefits**
The resulting data will help to determine the improvement of the anorectal and urogenital urinary function, alongside the postoperative quality of life after the application of pIONM in patients submitted to TME for rectal cancer.
Clinical trial: NCT04949646
Section: Purpose of Research
Subsections: 1. Purpose Of The Trial

The purpose of this study is to evaluate the improvement of the anorectal and urogenital urinary function, alongside the postoperative quality of life after the application of pIONM in patients submitted to TME for rectal cancer.  
2. **Procedure**
Participants will be admitted in the Department of Surgery of the University Hospital of Larissa to be operated for rectal cancer. Randomly, each patient will be allocated to one intervention group. In the first group pelvic neuromonitoring will be performed intraoperatively, while in the second group, no neurostimulation will be used. Postoperatively, the patient will be hospitalized in the surgery clinic. The patient will be discharged from the hospital when it will be medically safe to be released. Preoperatively and postoperatively, urogenital and anorectal functional assessment will be performed. The patient will be summoned to answer to specific questions at predefined time intervals, regarding the occurrence of adverse effects or complications, the quality of life and recurrence. Maximum follow up will be 1 year.