单倍型类群_O3_(Y-DNA)

**單倍群 O-M122**（英語：Haplogroup O-M122）是人類 Y 染色體 DNA 單倍群之一，現稱 O2（舊稱 O3）， 是單倍群 O-M175 的下游單倍群之一。

## 起源與分布

單倍群 O-M122 於 2 萬 5 千年至 3 萬年前首次出現於東亞南部。該單倍群目前主要分佈於東亞、玻里尼西亞、東南亞、中亞、南亞等。O-M122 的主要下游單倍群包括（以下均採用 ISOGG 2017 版命名）:O2a2a-M188、O2a1b-IMS-JST002611、O2a2b1a1-M117、O2a2b1a2-F114、O2a2b2-AM01822、O2b-F742 等。其中 O2a2a-M188 主要分佈在中國南方等地，其下游的 O2a2a1a2-M7 主要分佈在苗瑤語族各族。漢族主要由 O2a1b-IMS-JST002611、O2a2b1a1-M117、O2a2b1a2-F114 三個支系組成，三者比例相仿，也常見於蒙古族科爾沁部、滿族、朝鮮族等中，M117 也常見於藏緬語族各族中，F114 還在哈薩克族乃蠻部中高頻分布。O2a2b2-AM01822 主要分佈在中國華北偏東部地區等地，其下游的 O2a2b2a2b-AM01847 是玻里尼西亞人的主要單倍群。O2b-F742 主要分佈於中國東部沿海省份等地。

## 注釋

## 參考文獻

* Black, M. L.; Dufall, K.; Wise, C.; Sullivan, S.; Bittles, A. H. Genetic ancestries in northwest Cambodia. Annals of Human Biology. 2006, **33** (5–6): 620–7. PMID 17381059. doi:10.1080/03014460600882561.
* Cai, Xiaoyun; Qin, Zhendong; Wen, Bo; Xu, Shuhua; Wang, Yi; Lu, Yan; Wei, Lanhai; Wang, Chuanchao; et al. O'Rourke, Dennis , 編. Human Migration through Bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum Revealed by Y Chromosomes. PLoS ONE. 2011, **6** (8): e24282. Bibcode:2011PLoSO...624282C. PMC 3164178 . PMID 21904623. doi:10.1371/journal.pone.0024282.
* Cordaux, R.; Weiss, G; Saha, N; Stoneking, M. The Northeast Indian Passageway: A Barrier or Corridor for Human Migrations?. Molecular Biology and Evolution. 2004, **21** (8): 1525–33. PMID 15128876. doi:10.1093/molbev/msh151.
* Gan, Rui-Jing; Pan, Shang-Ling; Mustavich, Laura F.; Qin, Zhen-Dong; Cai, Xiao-Yun; Qian, Ji; Liu, Cheng-Wu; Peng, Jun-Hua; et al. Pinghua population as an exception of Han Chinese's coherent genetic structure. Journal of Human Genetics. 2008, **53** (4): 303–13. PMID 18270655. doi:10.1007/s10038-008-0250-x.
* Gayden, Tenzin; Cadenas, Alicia M.; Regueiro, Maria; Singh, Nanda B.; Zhivotovsky, Lev A.; Underhill, Peter A.; Cavalli-Sforza, Luigi L.; Herrera, Rene J. The Himalayas as a Directional Barrier to Gene Flow. The American Journal of Human Genetics. 2007, **80** (5): 884–94. PMC 1852741 . PMID 17436243. doi:10.1086/516757.
* Hammer, Michael F.; Karafet, Tatiana M.; Park, Hwayong; Omoto, Keiichi; Harihara, Shinji; Stoneking, Mark; Horai, Satoshi. Dual origins of the Japanese: Common ground for hunter-gatherer and farmer Y chromosomes. Journal of Human Genetics. 2005, **51** (1): 47–58. PMID 16328082. doi:10.1007/s10038-005-0322-0.
* He, Jun-Dong; Peng, Min-Sheng; Quang, Huy Ho; Dang, Khoa Pham; Trieu, An Vu; Wu, Shi-Fang; Jin, Jie-Qiong; Murphy, Robert W.; et al. Kayser, Manfred , 編. Patrilineal Perspective on the Austronesian Diffusion in Mainland Southeast Asia. PLoS ONE. 2012, **7** (5): e36437. Bibcode:2012PLoSO...736437H. PMC 3346718 . PMID 22586471. doi:10.1371/journal.pone.0036437.
* Hurles, M; Sykes, B; Jobling, M; Forster, P. The Dual Origin of the Malagasy in Island Southeast Asia and East Africa: Evidence from Maternal and Paternal Lineages. The American Journal of Human Genetics. 2005, **76** (5): 894–901. PMC 1199379 . PMID 15793703. doi:10.1086/430051.
* Jin, Han-Jun; Tyler-Smith, Chris; Kim, Wook. Batzer, Mark A , 編. The Peopling of Korea Revealed by Analyses of Mitochondrial DNA and Y-Chromosomal Markers. PLoS ONE. 2009, **4** (1): e4210. Bibcode:2009PLoSO...4.4210J. PMC 2615218 . PMID 19148289. doi:10.1371/journal.pone.0004210.
* Jing, Chen; Hui, LI; Zhen-Dong, QIN; Wen-Hong, LIU; Wei-Xiong, LIN; Rui-Xing, YIN; Li, JIN; Shang-Ling, PAN. Y-chromosome Genotyping and Genetic Structure of Zhuang Populations. Acta Genetica Sinica. 2006, **33** (12): 1060–72. PMID 17185165. doi:10.1016/S0379-4172(06)60143-1.
* Karafet, Tatiana; Xu, Liping; Du, Ruofu; Wang, William; Feng, Shi; Wells, R.S.; Redd, Alan J.; Zegura, Stephen L.; Hammer, Michael F. Paternal Population History of East Asia: Sources, Patterns, and Microevolutionary Processes. The American Journal of Human Genetics. 2001, **69** (3): 615–28. PMC 1235490 . PMID 11481588. doi:10.1086/323299.
* Karafet, Tatiana M.; Lansing, J. S.; Redd, Alan J.; Watkins, Joseph C.; Surata, S. P. K.; Arthawiguna, W. A.; Mayer, Laura; Bamshad, Michael; et al. Balinese Y-Chromosome Perspective on the Peopling of Indonesia: Genetic Contributions from Pre-Neolithic Hunter-Gatherers, Austronesian Farmers, and Indian Traders. Human Biology. 2005, **77** (1): 93–114. PMID 16114819. doi:10.1353/hub.2005.0030.
* Katoh, Toru; Munkhbat, Batmunkh; Tounai, Kenichi; Mano, Shuhei; Ando, Harue; Oyungerel, Ganjuur; Chae, Gue-Tae; Han, Huun; Jia, Guan-Jun; Tokunaga, Katsushi; Munkhtuvshin, Namid; Tamiya, Gen; Inoko, Hidetoshi. Genetic features of Mongolian ethnic groups revealed by Y-chromosomal analysis. Gene. 2005, **346**: 63–70. PMID 15716011. doi:10.1016/j.gene.2004.10.023.
* Kayser, M.; Brauer, S; Cordaux, R; Casto, A; Lao, O; Zhivotovsky, LA; Moyse-Faurie, C; Rutledge, RB; et al. Melanesian and Asian Origins of Polynesians: MtDNA and Y Chromosome Gradients Across the Pacific. Molecular Biology and Evolution. 2006, **23** (11): 2234–44. PMID 16923821. doi:10.1093/molbev/msl093.
* Kharkov, V. N.; Stepanov, V. A.; Medvedeva, O. F.; Spiridonova, M. G.; Voevoda, M. I.; Tadinova, V. N.; Puzyrev, V. P. Gene pool differences between Northern and Southern Altaians inferred from the data on Y-chromosomal haplogroups. Russian Journal of Genetics. 2007, **43** (5): 551–562. doi:10.1134/S1022795407050110.
* Kim, Wook; Yoo, Tag-Keun; Kim, Sung-Joo; Shin, Dong-Jik; Tyler-Smith, Chris; Jin, Han-Jun; Kwak, Kyoung-Don; Kim, Eun-Tak; Bae, Yoon-Sun. Blagosklonny, Mikhail , 編. Lack of Association between Y-Chromosomal Haplogroups and Prostate Cancer in the Korean Population. PLoS ONE. 2007, **2** (1): e172. Bibcode:2007PLoSO...2..172K. PMC 1766463 . PMID 17245448. doi:10.1371/journal.pone.0000172.
* Kumar, Vikrant; Reddy, Arimanda NS; Babu, Jagedeesh P; Rao, Tipirisetti N; Langstieh, Banrida T; Thangaraj, Kumarasamy; Reddy, Alla G; Singh, Lalji; Reddy, Battini M. Y-chromosome evidence suggests a common paternal heritage of Austro-Asiatic populations. BMC Evolutionary Biology. 2007, **7** (1): 47. PMC 1851701 . PMID 17389048. doi:10.1186/1471-2148-7-47.
* Li, Hui; Wen, Bo; Chen, Shu-Juo; Su, Bing; Pramoonjago, Patcharin; Liu, Yangfan; Pan, Shangling; Qin, Zhendong; Liu, Wenhong; Cheng, Xu; Yang, Ningning; Li, Xin; Tran, Dinhbinh; Lu, Daru; Hsu, Mu-Tsu; Deka, Ranjan; Marzuki, Sangkot; Tan, Chia-Chen; Jin, Li. Paternal genetic affinity between western Austronesians and Daic populations. BMC Evolutionary Biology. 2008, **8** (1): 146. PMC 2408594 . PMID 18482451. doi:10.1186/1471-2148-8-146.
* Nonaka, I.; Minaguchi, K.; Takezaki, N. Y-chromosomal Binary Haplogroups in the Japanese Population and their Relationship to 16 Y-STR Polymorphisms. Annals of Human Genetics. 2007, **71** (4): 480–95. PMID 17274803. doi:10.1111/j.1469-1809.2006.00343.x.
* Reddy, B. Mohan; Langstieh, B. T.; Kumar, Vikrant; Nagaraja, T.; Reddy, A. N. S.; Meka, Aruna; Reddy, A. G.; Thangaraj, K.; Singh, Lalji. Awadalla, Philip , 編. Austro-Asiatic Tribes of Northeast India Provide Hitherto Missing Genetic Link between South and Southeast Asia. PLoS ONE. 2007, **2** (11): e1141. Bibcode:2007PLoSO...2.1141R. PMC 2065843 . PMID 17989774. doi:10.1371/journal.pone.0001141.
* Shi, Simona; Pala, Maria; Battaglia, Vincenza; Maranta, Ramona; Achilli, Alessandro; Modiano, Guido; Torroni, Antonio; Semino, Ornella; Santachiara-Benerecetti, Silvana A. Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): A reservoir of genetic variation. BMC Evolutionary Biology. 2009, **9** (1): 154. PMC 2720951 . PMID 19573232. doi:10.1186/1471-2148-9-154.
* Su, B.; Jin, L.; Underhill, P.; Martinson, J.; Saha, N.; McGarvey, S. T.; Shriver, M. D.; Chu, J.; et al. Polynesian origins: Insights from the Y chromosome. Proceedings of the National Academy of Sciences. 2000, **97** (15): 8225–8228. Bibcode:2000PNAS...97.8225S. doi:10.1073/pnas.97.15.8225. \*H6 (=O-M122(xO-M7, O-M134)) in 18/73=24.7% \*H8 (=O-M134) in 2/73=2.7% for a total of 20/73=27.4% O-M122 in a pool of seven samples from Micronesia. \*13/40=32.5% O-M122(xM7,M134) in a pool of three samples from Polynesia. \*9/27=33.3% H6 (=O-M122(xM7,M134)) \*6/27=22.2% H8 (=O-M134) for a total of 15/27=55.6% O-M122 in "Malay" sample \*2/19=10.5% H6 (=O-M122(xM7,M134)) in "Kota Kinabalu" sample.
* Su, Bing; Xiao, Junhua; Underhill, Peter; Deka, Ranjan; Zhang, Weiling; Akey, Joshua; Huang, Wei; Shen, Di; et al. Y-Chromosome Evidence for a Northward Migration of Modern Humans into Eastern Asia during the Last Ice Age. The American Journal of Human Genetics. 1999, **65** (6): 1718–24. PMC 1288383 . PMID 10577926. doi:10.1086/302680.
* Tajima, Atsushi; Hayami, Masanori; Tokunaga, Katsushi; Juji, Takeo; Matsuo, Masafumi; Marzuki, Sangkot; Omoto, Keiichi; Horai, Satoshi. Genetic origins of the Ainu inferred from combined DNA analyses of maternal and paternal lineages. Journal of Human Genetics. 2004, **49** (4): 187–93. PMID 14997363. doi:10.1007/s10038-004-0131-x.
* Wang, Wei; Wise, Cheryl; Baric, Tom; Black, Michael L.; Bittles, Alan H. The origins and genetic structure of three co-resident Chinese Muslim populations: the Salar, Bo'an and Dongxiang. Human Genetics (Springer-Verlag). August 1, 2003, **113** (3): 244–52. ISSN 0340-6717. PMID 12759817. doi:10.1007/s00439-003-0948-y.
* Wells, R. S.; Yuldasheva, N.; Ruzibakiev, R.; Underhill, P. A.; Evseeva, I.; Blue-Smith, J.; Jin, L.; Su, B.; et al. The Eurasian Heartland: A continental perspective on Y-chromosome diversity. Proceedings of the National Academy of Sciences. 2001, **98** (18): 10244–9. Bibcode:2001PNAS...9810244W. PMC 56946 . PMID 11526236. doi:10.1073/pnas.171305098.
* Wen, Bo; Li, Hui; Lu, Daru; Song, Xiufeng; Zhang, Feng; He, Yungang; Li, Feng; Gao, Yang; et al. Genetic evidence supports demic diffusion of Han culture. Nature. 2004, **431** (7006): 302–5. Bibcode:2004Natur.431..302W. PMID 15372031. doi:10.1038/nature02878.
* Wen, Bo; Xie, Xuanhua; Gao, Song; Li, Hui; Shi, Hong; Song, Xiufeng; Qian, Tingzhi; Xiao, Chunjie; et al. Analyses of Genetic Structure of Tibeto-Burman Populations Reveals Sex-Biased Admixture in Southern Tibeto-Burmans. The American Journal of Human Genetics. 2004, **74** (5): 856–865. PMC 1181980 . PMID 15042512. doi:10.1086/386292.
* Wen, Bo; Hong, S; Ling, R; Huifeng, X; Kaiyuan, L; Wenyi, Z; Bing, S; Shiheng, S; et al. The origin of Mosuo people as revealed by mtDNA and Y chromosome variation. Science China Life Sciences. 2004, **47** (1): 1–10. PMID 15382670. doi:10.1360/02yc0207.
* Xie, Xuan-Hua. Genetic Structure of Tujia as Revealed by Y Chromosomes. [2017-04-07]. （原始內容存檔於 2019-07-19）.
* Xue, Y.; Zerjal, T; Bao, W; Zhu, S; Shu, Q; Xu, J; Du, R; Fu, S; et al. Male Demography in East Asia: A North-South Contrast in Human Population Expansion Times. Genetics. 2005, **172** (4): 2431–9. PMC 1456369 . PMID 16489223. doi:10.1534/genetics.105.054270.
* Yang, Zhili; Dong, Yongli; Gao, Lu; Cheng, Baowen; Yang, Jie; Zeng, Weimin; Lu, Jing; Su, Yanhua; Xiao, Chunjie. The distribution of Y chromosome haplogroups in the nationalities from Yunnan Province of China. Annals of Human Biology. 2005, **32** (1): 80–7. PMID 15788357. doi:10.1080/03014460400027557.
* Zhou, Ruixia; Yang, Daqun; Zhang, Hua; Yu, Weiping; An, Lizhe; Wang, Xilong; Li, Hong; Xu, Jiujin; Xie, Xiaodong. Origin and evolution of two Yugur sub-clans in Northwest China: A case study in paternal genetic landscape. Annals of Human Biology. 2008, **35** (2): 198–211. PMID 18428013. doi:10.1080/03014460801922927.
* Genographic Project, R. Spencer; Wells. The Genographic Project - Atlas of the Human Journey. [2017-04-07]. （原始內容存檔於 2011-02-05）.
* Krahn; FTDNA. Genomic Research Center Draft Tree (AKA Y-TRee). 2003 [2017-04-07]. （原始內容存檔於 2015-08-15）.