IARC第2B类致癌物

**2B 類致癌物**（英語：Group 2B carcinogens），為國際癌症研究機構（International Agency for Research on Cancer，IARC）對致癌物質的分類，此類物質（或其混合物）可能對人類致癌。現有 236 類物質（如黃樟素、四氯化碳、電磁波、抗甲狀腺藥物丙硫氧嘧啶（propylthiouracil）、二異氰酸甲苯、抗愛滋病藥物齊多夫定（zidovudine）、汽油引擎廢氣、乾洗業等），對人類為有可能致癌物，對動物為很可能也是致癌物。更多詳細信息，可以搜尋國際癌症研究機構（IARC）專著。

## 物質和物質組合

* 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
* Chloroform
* 1-Chloro-2-methylpropene
* Chlorophenoxy herbicides
* 4-Chloro-ortho-phenylenediamine
* Chloroprene
* Chlorothalonil
* Chrysene
* CI Acid Red 114
* CI Basic Red 9
* CI Direct Blue 15
* Citrus Red No. 2
* Cobalt and cobalt compounds 1
* Cobalt sulfate and other soluble cobalt(II) salts
* Coconut oil diethanolamine condensate
* para-Cresidine
* Cycasin
* Dacarbazine
* Dantron (Chrysazin, 1,8-Dihydroxyanthraquinone)
* Daunomycin
* DDT (_p_,_p'_-DDT)
* N,N'-Diacetylbenzidine
* 2,4-Diaminoanisole
* 4,4'-Diaminodiphenyl ether
* 2,4-Diaminotoluene
* Dibenz[_a,h_]acridine
* Dibenz[_a,j_]acridine
* 7_H_-Dibenzo[_c,g_]carbazole
* Dibenzo[_a,e_]pyrene
* Dibenzo[_a,h_]pyrene
* Dibenzo[_a,i_]pyrene
* 1,2-Dibromo-3-chloropropane
* 2,3-Dibromopropan-1-ol
* Dichloroacetic acid
* para-Dichlorobenzene
* 3,3'-Dichlorobenzidine
* 3,3'-Dichloro-4,4'-diaminodiphenyl ether
* 1,2-Dichloroethane
* Dichloromethane (methylene chloride)
* 1,3-Dichloropropene (technical grade)
* Dichlorvos
* 1,2-Diethylhydrazine
* Diglycidyl resorcinol ether
* Dihydrosafrole
* Diisopropyl sulfate
* 3,3'-Dimethoxybenzidine (_o_-Dianisidine)
* para-Dimethylaminoazobenzene
* _trans_-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
* 2,6-Xylidine (2,6-Dimethylaniline)
* 3,3'-Dimethylbenzidine (_o_-Tolidine)
* 1,1-Dimethylhydrazine
* 3,7-Dinitrofluoranthene
* 3,9-Dinitrofluoranthene
* 1,6-Dinitropyrene
* 1,8-Dinitropyrene
* 2,4-Dinitrotoluene
* 2,6-Dinitrotoluene
* 1,4-Dioxane
* Disperse Blue 1
* 1,2-Epoxybutane
* Ethyl acrylate
* Ethylbenzene
* Ethylene dichloride
* Ethyl methanesulfonate
* Foreign bodies, implanted in tissues

　
: : Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))

　
: Metallic, prepared as thin smooth films

　
: Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron

* 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
* Fumonisin B1
* Furan
* Glu-P-1 (2-Amino-6-methyldipyrido[1,2-_a_:3',2'-_d_]imidazole)
* Glu-P-2 (2-Aminodipyrido[1,2-_a_:3',2'-_d_]imidazole)
* Glycidaldehyde
* Griseofulvin
* HC Blue No. 1
* Heptachlor
* Hexachlorobenzene
* Hexachloroethane
* Hexachlorocyclohexanes
* Hexamethylphosphoramide (HMPA)
* Human immunodeficiency virus type 2 (infection with)
* Human papillomaviruses: some types other than 16, 18, 31 and 33
* Hydrazine
* 1-Hydroxyanthraquinone
* Indeno[1,2,3-_cd_]pyrene
* Iron-dextran complex
* Isoprene
* Lasiocarpine
* Lead
* Magnetic fields (extremely low frequency)
* MeA-a-C (2-Amino-3-methyl-9_H_-pyrido[2,3-_b_]indole)
* Medroxyprogesterone acetate
* MeIQ (2-Amino-3,4-dimethylimidazo[4,5-_f_]quinoline)
* MeIQx (2-Amino-3,8-dimethylimidazo[4,5-_f_]quinoxaline)
* Merphalan
* 2-Methylaziridine (Propyleneimine)
* Methylazoxymethanol acetate
* 5-Methylchrysene
* 4,4'-Methylene bis(2-methylaniline)
* 4,4'-Methylenedianiline
* Methylmercury compounds 1
* 2-Methyl-1-nitroanthraquinone (uncertain purity)
* N-Methyl-N-nitrosourethane
* Methylthiouracil
* Metronidazole
* Michler's base (4,4'-methylene-bis(_N_,_N_-dimethyl)benzenamine)
* Michler's ketone (4,4'-bis(dimethylamino)benzophenone)
* Microcystin-LR
* Mirex
* Mitomycin C
* Mitoxantrone
* Monocrotaline
* 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
* Nafenopin
* Naphthalene
* Nickel, metallic and alloys
* Niridazole
* Nitrilotriacetic acid and its salts 1
* 5-Nitroacenaphthene
* 2-Nitroanisole
* Nitrobenzene
* 6-Nitrochrysene
* Nitrofen (technical-grade)
* 2-Nitrofluorene
* 1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
* _N_-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
* Nitrogen mustard _N_-oxide
* Nitromethane
* 2-Nitropropane
* 1-Nitropyrene
* 4-Nitropyrene
* N-Nitrosodi-n-butylamine
* N-Nitrosodiethanolamine
* N-Nitrosodi-n-propylamine
* 3-(N-Nitrosomethylamino)propionitrile
* N-Nitrosomethylethylamine
* N-Nitrosomethylvinylamine
* N-Nitrosomorpholine
* N-Nitrosopiperidine
* N-Nitrosopyrrolidine
* N-Nitrososarcosine
* Ochratoxin A
* Oestrogen-progestogen therapy, postmenopausal
* Oil Orange SS
* Oxazepam
* Palygorskite (attapulgite) (long fibres, >5µm)
* Panfuran S (containing dihydroxymethylfuratrizine)
* Phenazopyridine hydrochloride
* Phenobarbital
* Phenolphthalein
* Phenoxybenzamine hydrochloride
* Phenyl glycidyl ether
* Phenytoin
* PhIP (2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine)
* Polychlorophenols and their sodium salts (mixed exposures)
* Ponceau MX
* Ponceau 3R
* Potassium bromate
* Progestins
* Progestogen-only contraceptives
* 1,3-Propane sultone
* β-Propiolactone
* Propylene oxide
* 硫月尿酮（Propylthiouracil、PTU），抗甲狀腺藥物
* Radiofrequency electromagnetic fields, such as, but not limited to, those associated with wireless phones
* Refractory ceramic fibres
* Riddelliine
* 黃樟素 Safrole
* _Schistosoma japonicum_ (infection with)
* Sodium _ortho_-phenylphenate
* Special-purpose fibres such as E-glass and '475' glass fibres
* Sterigmatocystin
* Streptozotocin
* Styrene
* Sulfallate
* Tetrafluoroethylene
* Tetranitromethane
* Thioacetamide
* 4,4'-Thiodianiline
* Thiouracil
* Titanium dioxide
* 二異氰酸甲苯（2,4-Toluene diiso-cyanate, 2,4-TDI）
* Trichlormethine (Trimustine hydrochloride)
* Trp-P-1 (3-Amino-1,4-dimethyl-5_H_-pyrido[4,3-_b_]indole)
* Trp-P-2 (3-Amino-1-methyl-5_H_-pyrido[4,3-_b_]indole)
* Trypan blue
* Uracil mustard
* Vanadium pentoxide
* Vinyl acetate
* 4-Vinylcyclohexene
* 4-Vinylcyclohexene diepoxide
* Zalcitabine
* 齊多夫定（Zidovudine，AZT）

## 混合物

* 瀝青
* 角叉菜膠
* 氯化石蠟
* 柴油
* 汽油發動機尾氣
* 重油
* 汽油
* 品紅染料
* 醃、泡製的蔬菜（一些亞洲傳統食品）
* 多溴化聯苯（多溴聯苯標準品）
* 毒殺芬（多氯莰烯）
* 串珠鐮刀菌分泌的毒素
* 焊接煙塵

## 接觸場合

* 房屋建材與木工裝潢
* 鈷（未存放於碳化鎢盒內）
* 乾洗
* 消防
* 印刷過程
* 滑石粉（粉塵）
* 紡織工業（生產過程）

## 注釋

**腳註**

* **^1** Evaluated as a group.
* **^2** There is limited evidence in humans that coffee drinking is carcinogenic in the urinary bladder.
* **^3** There is some evidence of an inverse relationship between coffee drinking and cancer of the large bowel.

## 引用

## 外部連結

* 致癌物分類表描述，國際癌症研究機構
  * 致癌物分類表（最新版本）
  * （頁面存檔備份，存於網際網路檔案館）（2015 年 11 月 5 日更新）