Bayer Trademarks Aspirin Bayer Trademarks Aspirin by christopher-mahoney Bayer AG was founded in Germany by Friederich Bayer in 1863. The pharmaceuticals company’s first major product was acetylsalicylic acid, which is derived from a remedy found in willow plant bark. It was discovered that acetylsalicylic acid could be used as an anti-inflammatory medication, as well as for minor pain/ache relief and fever reduction. Today acetylsalicylic acid is known as aspirin. On this day, March 6th, in 1899, Bayer registers aspirin as a trademark. Bayer’s trademark was registered worldwide, but the company’s U.S. assets and trademarks were confiscated by the the United States during World War I. As a result, aspirin became the generic term to describe the drug for all brands in the U.S., France and the United Kingdom. Aspirin remains a trademark for Bayer in over seventy other countries. Aspirin is currently one of the most used over-the-counter drugs in the world.

Several other benefits of aspirin have been discovered, such as its effective treatment of headaches and its long term benefits of heart attack and stroke prevention. Although Bayer may have lost its trademark of the Aspirin name, the company’s contribution to the pharmaceutical industry is not tarnished. Today’s History Aspirin (Acetylsalicylic Acid) - Home Aspirin (Acetylsalicylic Acid) Functional Groups: Carboxylic Acid, Ester, Aromatic Group 3D Rendering of Aspirin Boiling Point: 136 °C (277 °F) Melting Point: 140 °C (284 °F) IUPAC Name 3) 109.5 Hybridization All the carbons except CH3 are sp2 .CH 3 is sp3. All the O atoms have lone pairs of electrons. History Aspirin was first isolated by Felix Hoffmann, a chemist with the German company Bayer in 1897. Plant extracts, including willow bark and spiraea, of which salicylic acid was the active ingredient, had been known to help alleviate headaches, pains, and fevers since antiquity.

The father of modern medicine, Hippocrates, who lived sometime between 460 BC and 377 BC, left historical records describing the use of powder made from the bark and leaves of the willow tree to help these symptoms.Today, aspirin is one of the most widely used medications in the world, with an estimated 40,000 tonnes of it being consumed each year. In countries where Aspirin is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid. Common Uses Aspirin is used to relieve pain, fever, and inflammation in various conditions such as lower back and neck pain, the flu, common cold, burns, menstrual pain, headache, migraines, osteoarthritis, rheumatoid arthritis, sprains and strains, nerve pain, toothache, muscle pain, bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and following surgical and dental procedures. Aspirin is also used for rheumatic fever in combination with other medications.

Effects on Human Body Aspirin should not be taken by people who are allergic to ibuprofen or naproxen,or who have salicylate intolerance or a more generalized drug intolerance to NSAIDs, and caution should be exercised in those with asthma. To its effect on the stomach lining, manufacturers recommend people with peptic ulcers, mild diabetes, or gastritis seek medical advice before using aspirin. Even if none of these conditions is present, the risk of stomach bleeding is still increased when aspirin is taken with alcohol. Children and teens are not supposed to be given Aspirin to control cold or influenza symptoms, because it has been linked with Reye's syndrome. Reye's syndrome, a rare and severe illness characterized by acute encephalopathy and fatty liver, it can occur when children and teens are given aspirin for a fever or other illnesses or infections. People who have a salicylate intolerance may get hives or headaches when taking Aspirin. Interesting Facts about Aspirin In 1950, aspirin was entered into the Guinness Book of Records as the highest-selling drug product. Approximately 3,500 scientific articles about aspirin are published per year.

The number of 50mg aspirin tablets manufactured each year is around 100 billion Adding aspirin to water in a vase will make cut flowers last longer. The effect is attributable to salicylic acid, which as a messenger substance plays an important role in plants’ defense systems. Before 1904, Bayer sold aspirin to pharmacies as a fine, white powder in bottles. The pharmacists in turn filled 500-milligram portions of the product into paper bags which they then sold to the customers. After becoming world famous for developing aspirin, Felix Hoffmann disappeared completely from the public eye on retiring in 1928, emigrating to Switzerland where he lived in seclusion and devoted himself to art history until his death in 1946. After aspirin was developed in 1897, it was around 70 years before British scientist Professor Sir John R. Vane made the Nobel Prize winning discovery that it worked by inhibiting prostaglandins (pain messenger substances).

Aspirin went into space, as part of the on-board medicine kit on all of the Apollo rockets that NASA sent to the moon – both the orbital lunar flights in 1968/69 and the seven moon landings from 1969 to 1972 (Apollo 11 to Apollo 17). Aspirin was used as currency during times of hyperinflation in South America last century, when money became next to worthless. According to reports, it was standard practice at that time to hand out a few tablets of the analgesic as change as it held its value considerably better than the actual currency. Create a free website Aspirin - FAQ FAQ How does Aspirin work to alleviate pain, fever and inflammation? The active ingredient in Aspirin is acetylsalicylic acid. The mechanism of action of acetylsalicylic acid has been widely documented and described in the available literature. Acetylsalicylic acid inhibits the production of certain substances in the human body — known as prostaglandins — which mediate pain, fever and inflammation that may accompany injuries. Consequently: pain is relieved, fever is lowered and inflammation is reduced.

How does Aspirin work to help prevent heart attacks and strokes? Aspirin interferes with your blood's clotting action. When you bleed, your blood's clotting cells, called platelets, build up at the site of your wound. The platelets help form a plug that seals the opening in your blood vessel to stop bleeding. But this clotting can also happen within the vessels that supply your heart with blood. If your blood vessels are already narrowed from atherosclerosis — the buildup of fatty deposits in your arteries — a fatty deposit in your vessel lining can burst. Then, a blood clot can quickly form and block the artery. This prevents blood flow to parts of the heart or brain which can cause a heart attack or clot-related stroke. Aspirin therapy reduces the clumping action of platelets and keeps the blood flowing freely, potentially preventing further damage from a heart attack or clot-related stroke. Is Aspirin well tolerated? When used as directed, acetylsalicylic acid has shown to be safe and well tolerated – based upon the evidence of use by millions of people over one hundred years – an outstanding track record of safety and efficacy. In spite of this – as with all medications – Aspirin may have unwanted side effects.

Can Aspirin interact with other drugs? In spite of the fact that acetylsalicylic acid is compatible with most prescription drugs on the market, we nevertheless recommend that you talk to your doctor before taking Aspirin if you are already being treated with any other medication. If you are taking a prescription drug for anticoagulation (blood thinning), diabetes, gout or arthritis, you should be sure to consult your doctor before taking Aspirin. Can I take Aspirin if I have diabetes? If you have diabetes, it is advisable to talk to your doctor, who will be well acquainted with your history and medications, in order to answer this question. Aspirin may interact with certain older diabetes medications. In view of the increased risk of cardiovascular events in patients with diabetes, the administration of Aspirin may be beneficial, taking into account the individual circumstances on a case-to-case basis. Can Aspirin be taken during pregnancy? Pregnant women should not take acetylsalicylic acid during the last three months of their pregnancy.

Furthermore, as a rule it is not advisable for pregnant women to take acetylsalicylic acid during the first six months of their pregnancy, unless definitely directed to do so and closely monitored by their doctor. What is the difference between Aspirin® and so-called generic acetylsalicylic acid products? The active ingredient in Aspirin, acetylsalicylic acid, was synthesized in a pure and stable form by Bayer over 100 years ago and the products have been further refined since then. Bayer has even created the “International Aspirin Award” on behalf of scientists from all over the world for outstanding scientific work in the field of research on Aspirin. You will only be assured that you are taking the original Aspirin products manufactured by Bayer when you see the word Aspirin® or Bayer® Aspirin on the packaging. A product’s formulation can have a substantial impact on its effectiveness or efficacy. Bayer, as originator of Aspirin, invests substantial efforts in its formulations, which can have a substantial impact on efficacy. How long has Aspirin existed?

Acetylsalicylic acid, the active ingredient in Aspirin was synthesized in a chemically pure and stable form for the first time in 1897 by a young Bayer chemist, Dr. Felix Hoffmann and his team. Two years later, acetylsalicylic acid was launched in Germany under the brand name Aspirin. What is the origin of the trade name “Aspirin”? The letter “A” stands for Acetyl, which is the remaining portion of acetic acid in the molecule of the product’s active ingredient, acetylsalicylic acid. The next syllable,“spir”, is derived from the plant known as Spirea ulmaria, which yields salicin, a sugar combination of salicylic acid. Salicylic acid is the base product from which acetylsalicylic acid is synthesized. The ending, “in”, was a common suffix used for drugs at the time of the very first stable synthesis of acetylsalicylic acid by Felix Hoffmann in 1897. Does Aspirin interact with other medicines?

Aspirin is compatible with most prescription drugs; however, please refer to the label (leaflet) or consult your pharmacist or doctor before taking Aspirin in combination with any other drugs. Unlike ibuprofen, which can sometimes interfere with the antiplatelet benefit of aspirin, taking Aspirin for pain relief won’t interfere with the antiplatelet benefit of a prescribed cardiovascular-protective aspirin regimen. What is New Aspirin? New Aspirin is the reinvention of Aspirin by Bayer Consumer Health, and an exciting innovation in pain relief. The next generation of Aspirin, New Aspirin employs patent-pending micro-active technology that results in faster pain relief; it is clinically proven to deliver pain relief twice as fast as previous Aspirin tablets. 1 Is New Aspirin safe? Yes, acetylsalicylic acid, the active ingredient in New Aspirin, has a well-established safety profile and is safe when used as directed. 2,3 In addition, New Aspirin’s rapid dissolution in the body and quick absorption into the bloodstream can contribute to a favourable safety and tolerability profile. 2,3 How does Bayer Consumer Health’s micro-active technology work?

The technology is a proprietary formulation that utilizes patent-pending micro-active technology to boost the rate of absorption and time-to-relief of acetylsalicylic acid, the active ingredient in New Aspirin tablets. The technology combines a smaller particle size of ASA with sodium carbonate, which acts as a disintegrant, resulting in the active ingredient being quickly available in the body and readily absorbed. 2 Can you take New Aspirin for pain relief if you are already on a doctor-recommended cardiovascular-protective regimen? Yes. Be sure to follow label directions and do not take more than total recommended dose in one day. Unlike ibuprofen, which can sometimes interfere with the antiplatelet benefit of aspirin, taking New Aspirin for pain relief won’t interfere with the antiplatelet benefit of a prescribed cardiovascular-protective aspirin regimen. Why are you reformulating Aspirin after more than a century? With the introduction of Aspirin in 1899, Bayer Consumer Health offered one of the first widely accessible analgesics, or pain relievers, to consumers and helped to create the self-medication pain relief category.

Now, through a combination of technological innovation and rich analgesic heritage, Bayer Consumer Health is introducing a new standard in acetylsalicylic acid for mild to moderate pain relief with New Aspirin. In what other countries will the new product be available? Bayer’s New Aspirin is being introduced to European and Latin American consumers in approximately 25 countries through 2016. 1 Cooper SA, Voelker M. Evaluation of onset of pain relief from micronized aspirin in a dental pain model. Inflammopharmacology 2012; 20:233-242 2 Lanas A, et al. Short-Term Aspirin Use for Pain and Cold: Gastrointestinal Adverse Effects. Drugs in R&D. 2011; 11: 277-288 3 Baron JA, et al. Gastrointestinal Adverse Effects of Short term Aspirin use: A Meta-analysis of Published Randomized Controlled Trials. Drugs in R&D 2013;13:9-16 Why do I need to take daily medication?

There can be two reasons, why your doctor has recommended you to take Aspirin Protect: 1. You have already experienced a first heart attack or ischemic (clot related) stroke – then, a daily dose of Aspirin Protect will help prevent a second event 2. You may have several risk factors for cardiovascular disease, such as high cholesterol levels or high blood pressure; you may have diabetes or a family history of cardiovascular disease – then, Aspirin Protect can help prevent the development of a heart attack. Some people can be at risk of cardiovascular disease without being aware of it, so it is essential for you to follow your doctor’s recommendation even if you feel healthy. What is cardiovascular disease? Cardiovascular disease affects the heart and blood vessels. Cardiovascular events, such as heart attack and stroke, can develop as a result of the effects of a range of cardiovascular risk factors. Risk factors such as high cholesterol levels, high blood pressure, diabetes, and cigarette smoking all cause damage to the blood vessels and lead to the development of cardiovascular disease. How does Aspirin Protect work for my heart? Aspirin Protect helps to prevent the formation of blood clots in your blood vessels that can lead to heart attack or ischemic stroke.

It works by preventing blood platelets (thrombocytes) from clumping together, thus helping to keep the blood flowing freely. When too many platelets, along with other substances in the blood, build up in the inner layer of an artery, a clot can form and cause a heart attack or ischemic stroke. Why should I take Aspirin Protect from Bayer? As the inventor of Aspirin, Bayer has developed and improved this drug for more than a century and is continuing to do so every day. Aspirin Protect from Bayer is a high-quality brand, trusted by doctors and helping millions of patients worldwide to live a long and happy life. How does Aspirin work to alleviate pain, fever and inflammation? The active ingredient in Aspirin is acetylsalicylic acid. The mechanism of action of acetylsalicylic acid has been widely documented and described in the available literature. Acetylsalicylic acid inhibits the production of certain substances in the human body — known as prostaglandins — which mediate pain, fever and inflammation that may accompany injuries. Consequently: pain is relieved, fever is lowered and inflammation is reduced. How does Aspirin work to help prevent heart attacks and strokes?

Aspirin interferes with your blood's clotting action. When you bleed, your blood's clotting cells, called platelets, build up at the site of your wound. The platelets help form a plug that seals the opening in your blood vessel to stop bleeding. But this clotting can also happen within the vessels that supply your heart with blood. If your blood vessels are already narrowed from atherosclerosis — the buildup of fatty deposits in your arteries — a fatty deposit in your vessel lining can burst. Then, a blood clot can quickly form and block the artery. This prevents blood flow to parts of the heart or brain which can cause a heart attack or clot-related stroke. Aspirin therapy reduces the clumping action of platelets and keeps the blood flowing freely, potentially preventing further damage from a heart attack or clot-related stroke. Is Aspirin well tolerated? When used as directed, acetylsalicylic acid has shown to be safe and well tolerated – based upon the evidence of use by millions of people over one hundred years – an outstanding track record of safety and efficacy. In spite of this – as with all medications – Aspirin may have unwanted side effects. Can Aspirin interact with other drugs?

In spite of the fact that acetylsalicylic acid is compatible with most prescription drugs on the market, we nevertheless recommend that you talk to your doctor before taking Aspirin if you are already being treated with any other medication. If you are taking a prescription drug for anticoagulation (blood thinning), diabetes, gout or arthritis, you should be sure to consult your doctor before taking Aspirin. Can I take Aspirin if I have diabetes? If you have diabetes, it is advisable to talk to your doctor, who will be well acquainted with your history and medications, in order to answer this question. Aspirin may interact with certain older diabetes medications. In view of the increased risk of cardiovascular events in patients with diabetes, the administration of Aspirin may be beneficial, taking into account the individual circumstances on a case-to-case basis. Can Aspirin be taken during pregnancy? Pregnant women should not take acetylsalicylic acid during the last three months of their pregnancy. Furthermore, as a rule it is not advisable for pregnant women to take acetylsalicylic acid during the first six months of their pregnancy, unless definitely directed to do so and closely monitored by their doctor.

What is the difference between Aspirin® and so-called generic acetylsalicylic acid products? The active ingredient in Aspirin, acetylsalicylic acid, was synthesized in a pure and stable form by Bayer over 100 years ago and the products have been further refined since then. Bayer has even created the “International Aspirin Award” on behalf of scientists from all over the world for outstanding scientific work in the field of research on Aspirin. You will only be assured that you are taking the original Aspirin products manufactured by Bayer when you see the word Aspirin® or Bayer® Aspirin on the packaging. A product’s formulation can have a substantial impact on its effectiveness or efficacy. Bayer, as originator of Aspirin, invests substantial efforts in its formulations, which can have a substantial impact on efficacy. How long has Aspirin existed? Acetylsalicylic acid, the active ingredient in Aspirin was synthesized in a chemically pure and stable form for the first time in 1897 by a young Bayer chemist, Dr. Felix Hoffmann and his team.

Two years later, acetylsalicylic acid was launched in Germany under the brand name Aspirin. What is the origin of the trade name “Aspirin”? The letter “A” stands for Acetyl, which is the remaining portion of acetic acid in the molecule of the product’s active ingredient, acetylsalicylic acid. The next syllable,“spir”, is derived from the plant known as Spirea ulmaria, which yields salicin, a sugar combination of salicylic acid. Salicylic acid is the base product from which acetylsalicylic acid is synthesized. The ending, “in”, was a common suffix used for drugs at the time of the very first stable synthesis of acetylsalicylic acid by Felix Hoffmann in 1897. Does Aspirin interact with other medicines? Aspirin is compatible with most prescription drugs; however, please refer to the label (leaflet) or consult your pharmacist or doctor before taking Aspirin in combination with any other drugs.

Unlike ibuprofen, which can sometimes interfere with the antiplatelet benefit of aspirin, taking Aspirin for pain relief won’t interfere with the antiplatelet benefit of a prescribed cardiovascular-protective aspirin regimen. What is New Aspirin? New Aspirin is the reinvention of Aspirin by Bayer Consumer Health, and an exciting innovation in pain relief. The next generation of Aspirin, New Aspirin employs patent-pending micro-active technology that results in faster pain relief; it is clinically proven to deliver pain relief twice as fast as previous Aspirin tablets. 1 Why do I need to take daily medication? There can be two reasons, why your doctor has recommended you to take Aspirin Protect: 1. You have already experienced a first heart attack or ischemic (clot related) stroke – then, a daily dose of Aspirin Protect will help prevent a second event 2. You may have several risk factors for cardiovascular disease, such as high cholesterol levels or high blood pressure; you may have diabetes or a family history of cardiovascular disease – then, Aspirin Protect can help prevent the development of a heart attack.

Some people can be at risk of cardiovascular disease without being aware of it, so it is essential for you to follow your doctor’s recommendation even if you feel healthy. What is cardiovascular disease? Cardiovascular disease affects the heart and blood vessels. Cardiovascular events, such as heart attack and stroke, can develop as a result of the effects of a range of cardiovascular risk factors. Risk factors such as high cholesterol levels, high blood pressure, diabetes, and cigarette smoking all cause damage to the blood vessels and lead to the development of cardiovascular disease. How does Aspirin Protect work for my heart? Aspirin Protect helps to prevent the formation of blood clots in your blood vessels that can lead to heart attack or ischemic stroke. It works by preventing blood platelets (thrombocytes) from clumping together, thus helping to keep the blood flowing freely. When too many platelets, along with other substances in the blood, build up in the inner layer of an artery, a clot can form and cause a heart attack or ischemic stroke.

Bayer patents aspirin - Mar 06, 1899 - HISTORY.com Bayer patents aspirin Publisher A+E Networks On this day in 1899, the Imperial Patent Office in Berlin registers Aspirin, the brand name for acetylsalicylic acid, on behalf of the German pharmaceutical company Friedrich Bayer & Co. Now the most common drug in household medicine cabinets, acetylsalicylic acid was originally made from a chemical found in the bark of willow trees. In its primitive form, the active ingredient, salicin, was used for centuries in folk medicine, beginning in ancient Greece when Hippocrates used it to relieve pain and fever. Known to doctors since the mid-19thcentury, it was used sparingly due to its unpleasant taste and tendency to damage the stomach. In 1897, Bayer employee Felix Hoffman found a way to create a stable form of the drug that was easier and more pleasant to take.

(Some evidence shows that Hoffman’s work was really done by a Jewish chemist, Arthur Eichengrun, whose contributions were covered up during the Nazi era.) After obtaining the patent rights, Bayer began distributing aspirin in powder form to physicians to give to their patients one gram at a time. The brand name came from “a” for acetyl, “spir” from the spirea plant (a source of salicin) and the suffix “in,” commonly used for medications. It quickly became the number-one drug worldwide. Aspirin was made available in tablet form and without a prescription in 1915. Two years later, when Bayer’s patent expired during the First World War, the company lost the trademark rights to aspirin in various countries. After the United States entered the war against Germany in April 1917, the Alien Property Custodian, a government agency that administers foreign property, seized Bayer’s U.S. assets. Two years later, the Bayer company name and trademarks for the United States and Canada were auctioned off and purchased by Sterling Products Company, later Sterling Winthrop, for $5.3 million.

Bayer became part of IG Farben, the conglomerate of German chemical industries that formed the financial heart of the Nazi regime. After World War II, the Allies split apart IG Farben, and Bayer again emerged as an individual company. Its purchase of Miles Laboratories in 1978 gave it a product line including Alka-Seltzer and Flintstones and One-A-Day Vitamins. In 1994, Bayer bought Sterling Winthrop’s over-the-counter business, gaining back rights to the Bayer name and logo and allowing the company once again to profit from American sales of its most famous product. Related Videos All About Aspirin™ - Bayer Aspirin™ becomes available without a prescription and becomes a best-seller in the USA. 1949 Aspirin™ turns 50, and the following year, is for the first time featured in the Guinness Book of Records as the most frequently sold pain reliever in the world. 1969 A box of Aspirin™ flies to the moon aboard Apollo 11.

1977 A study reports that Aspirin™ can prevent ischemic stroke in appropriate patients.6 In the same year, the World Health Organization (WHO) introduces its “Essential Drug List”. Aspirin™ is included right from the start as an essential analgesic. 1982 British pharmacologist Professor John Vane receives the Noble Prize for Medicine for his discovery that the anti-inflammatory properties of Aspirin™ result from its ability to inhibit the body’s production of certain chemical mediators (prostaglandins) that promote inflammation. 1983 Publication of the Veterans Administration Cooperative Study (VACS) trial, one of the five key trials demonstrating that Aspirin™ reduces the risk of events in patients with angina.7 1993 Bayer introduces, in Germany and other various countries, Aspirin™ Protect, a low-dose Aspirin™ formulation for use by appropriate at-risk patients in the prevention of cardiovascular events. 1997 Acetylsalicylic acid, the active ingredient in Aspirin™, celebrates its centenary. Results of the International Stroke Trial, with nearly 20,000 patients in 36 countries, are published.

They support use of Aspirin™ within 48 hours after ischemic stroke.8 1999 On March 6, exactly 100 years after Aspirin™ was entered into the trademark register of the Imperial Patent Office in Berlin, Bayer set a Guinness world record by transforming its 122 meter tall headquarters building in Leverkusen into the largest Aspirin™ box. The building is wrapped with more than 22,500 square meters of fabric to celebrate the 100th birthday of Aspirin™. Aspirin™ takes its place among such medical advances as the stethoscope and artificial heart when it is inducted into the Smithsonian Institution’s National Museum of American History, USA. 2004 British researcher Professor Derek W. Gilroy elucidates the anti-inflammatory properties of Aspirin™,9 adding to previous research on its mechanism of action by Sir John Vane and others.

2012 Publication in the journal Headache by Lampl et al, which reaffirms the effectiveness of Aspirin™ as a first-line treatment of migraine or episodic tension type headache and finds that pre-treatment headache intensity does not predict potential success or failure of Aspirin™.10 2012 Bayer’s global Aspirin™ business continues to exhibit significant sales performance and remains one of the company’s top ten brands. Today, Aspirin™ is one of the top three branded over the counter analgesics worldwide. 2014 Beginning with the launch in Germany (the birthplace of Aspirin™) New Aspirin™ is being introduced to consumers in countries throughout Europe and Latin America. The active ingredient of New Aspirin™, acetylsalicylic acid, is used in the form of microparticles that are on average 10 percent of the size of particles found in previous Aspirin™ tablets. Microparticles are combined with sodium carbonate, which acts as a disentigrant and local buffer, helping New Aspirin™ dissolve more quickly, enter the bloodstream faster, and relieve pain twice as fast as previous Aspirin™ tablets11,12.

1 Who List of Essential Medications: 17th List, March, 2011. (accessed March 22, 2013). 2 Lanas, et al. Short-term Aspirin™ use for pain and cold: gastrointestinal adverse effects. Drugs in R&D. 2011;11: 277–288. 3 Baron JA, Senn S, Voelker M et al. gastrointestinal adverse effects of short term Aspirin™ use: a meta-analysis of published randomized controlled trials. Drugs in R&D 2013;13(1):9–16. 4 Weisman S, Graham D. Evaluation of the benefits and risks of low-dose Aspirin™ in the secondary prevention of cardiovascular and cerebrovascular events. Arch Intern Med 2002;162(19):2197–2202. 5 Antithrombotic Trialists’ (ATT) Collaboration. Aspirin™ in the primary and secondary prevention of vascular disease: collaborative metaanalysis of individual participant data from randomized clinical trials.

Lancet 2009; 373:1849–1860. 6 Genton E, Barnett HJ, Fields WS et al. XIV. Cerebral ischemia: the role of thrombosis and of antithrombotic therapy. Study group on antithrombotic therapy. Stroke 1977;8(1):150–175. 7 Lewis HD Jr, Davis JW, Archibald DG et al. Protective effects of Aspirin™ against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study. N Engl J Med 1983;309(7):396–403. 8 International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomized trial of Aspirin™, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. Lancet 1997;349(9065):1569–1581.

9 Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N et al. 15-epi-lipoxin A4-mediated induction of nitric oxide explains how Aspirin™ inhibits acute inflammation. J Exp Med 2004;200(1):69–78. 10 Lampl C, Voelker M, Steiner TJ. Aspirin™ is First-Line Treatment for Migraine and Episodic Tension-Type Headache Regardless of Headache Intensity. Headache 2012;52(1):48–56. 11 Voelker M.,Hammer M., Inflammopharmacology 2012;20:225-231 12 Acetylsalicyclic acid - definition of Acetylsalicyclic acid by The Free Dictionary Acetylsalicyclic acid - definition of Acetylsalicyclic acid by The Free Dictionary (ăs′pər-ĭn, -prĭn) n. pl. aspirin or as·pi·rins 1.

A white, crystalline compound, C9H8O4, derived from salicylic acid and commonly used in tablet form to relieve pain and reduce fever and inflammation. It is also used as an antiplatelet agent. Also called acetylsalicylic acid. 2. A tablet of aspirin. [Originally a trademark.] (ˈæsprɪn) n, pl -rin or -rins 1. (Pharmacology) a white crystalline compound widely used in the form of tablets to relieve pain and fever, to reduce inflammation, and to prevent strokes. Formula: CH3COOC6H4COOH. Chemical name: acetylsalicylic acid 2. (Pharmacology) a tablet of aspirin [C19: from German, from A(cetyl) + Spir(säure) spiraeic acid (modern salicylic acid) + -in; see also spiraea] as•pi•rin (ˈæs pər ɪn, -prɪn) n., pl. -rin, -rins. 1.

a white, crystalline substance, C9H8O4, derivative of salicylic acid, used as an anti-inflammatory agent and to relieve pain and fever; acetylsalicylic acid. 2. a tablet of this. [1899; < German, orig. a trademark, =A(cetyl) acetyl + Spir(säure) salicylic acid (see spirea ) + -in -in 1] as·pi·rin (ăs′pər-ĭn, ăs′prĭn) A white crystalline compound derived from salicylic acid and used as a drug to relieve fever and pain. Also called acetylsalicylic acid. Did You Know? The forest may not look like a drugstore. Nevertheless, plants have always provided humans with powerful medicine. For example, we no longer eat the bark of willow trees when we have headaches, but for thousands of years, people in pain did just that. About 100 years ago, scientists studying willow bark figured out how it could be used to make acetylsalicylic acid, better known as aspirin.

Aspirin and willow bark get broken down in the stomach to supply us with the same powerful painkiller. Quinine, which people use to control the fevers of the disease malaria, originally came from the cinchona tree. Just recently, researchers developed a new cancer drug, taxol, from the needles of yew trees. In fact, about 45 percent of all cancer drugs are either natural products or slightly altered natural chemicals that scientists tinkered with to make more potent. Researchers still study traditional plant remedies in the hopes of finding even more medicines from nature. ThesaurusAntonymsRelated WordsSynonymsLegend: March 06, 1899 : Bayer patents aspirin Introduction On this day in 1899, the Imperial Patent Office in Berlin registers Aspirin, the brand name for acetylsalicylic acid, on behalf of the German pharmaceutical company Friedrich Bayer & Co. Now the most common drug in household medicine cabinets, acetylsalicylic acid was originally made from a chemical found in the bark of willow trees.

In its primitive form, the active ingredient, salicin, was used for centuries in folk medicine, beginning in ancient Greece when Hippocrates used it to relieve pain and fever. Known to doctors since the mid-19thcentury, it was used sparingly due to its unpleasant taste and tendency to damage the stomach. In 1897, Bayer employee Felix Hoffman found a way to create a stable form of the drug that was easier and more pleasant to take. (Some evidence shows that Hoffman’s work was really done by a Jewish chemist, Arthur Eichengrun, whose contributions were covered up during the Nazi era.) After obtaining the patent rights, Bayer began distributing aspirin in powder form to physicians to give to their patients one gram at a time. The brand name came from “a” for acetyl, “spir” from the spirea plant (a source of salicin) and the suffix “in,” commonly used for medications. It quickly became the number-one drug worldwide. Aspirin was made available in tablet form and without a prescription in 1915. Two years later, when Bayer’s patent expired during the First World War, the company lost the trademark rights to aspirin in various countries.

After the United States entered the war against Germany in April 1917, the Alien Property Custodian, a government agency that administers foreign property, seized Bayer’s U.S. assets. Two years later, the Bayer company name and trademarks for the United States and Canada were auctioned off and purchased by Sterling Products Company, later Sterling Winthrop, for $5.3 million. Bayer became part of IG Farben, the conglomerate of German chemical industries that formed the financial heart of the Nazi regime. After World War II, the Allies split apart IG Farben, and Bayer again emerged as an individual company. Its purchase of Miles Laboratories in 1978 gave it a product line including Alka-Seltzer and Flintstones and One-A-Day Vitamins. In 1994, Bayer bought Sterling Winthrop’s over-the-counter business, gaining back rights to the Bayer name and logo and allowing the company once again to profit from American sales of its most famous product. Article Details: March 06, 1899 : Bayer patents aspirin Author March 06, 1899 : Bayer patents aspirin URL Bayer Corp.

Once Infected Millions Of People with HIV - The Ring of Fire Network Bayer Corp. Once Infected Millions Of People with HIV Bayer Corp. Once Infected Millions Of People with HIV April 15, 2015 Tweet on Twitter In the 1980s, German-based pharmaceutical corporation Bayer, sold blood plasma treatments to patients with hemophilia, knowing the treatments were contaminated with HIV. Millions of patients around the world later died of this dreaded infection. Almost thirty years later, the company admitted to having to pay $600 million in settlements to families of the victims (while denying any wrongdoing, naturally). This story has been reappearing on websites all over the Internet in recent weeks. What is odd however, is that for three decades, this story has been flying under the radar, virtually unknown to the general public. Most of the contaminated product was sold to patients in developing countries of Asia and Latin America, putting a racist slant on the story. It wouldn’t have been the first time.

A Checkered Past Founded in Bavaria in 1863, Bayer built its brand on a medication called acetylsalicylic acid, a willow-bark derivative better known by its then-trademark name, “aspirin.” Bayer lost that trademark as part of reparations in the wake of Germany’s defeat in the First World War. In the 1920s, Bayer was acquired by IG Farben, a large chemical firm. During the Second World War, this conglomerate operated factories near the infamous concentration camps – primarily Auschwitz and Mauthausen-Gusen. In addition to the company’s use of slave labor, IG Farben also engaged in human “medical experiments” on internees. After Germany’s defeat, Bayer was again separated from IG Farben. One of the latter’s board members, Fritz ter Meer, had been instrumental in the planning and construction of death facilities. Convicted for war crimes and sentenced to seven years imprisonment, he served only three years of that sentence – after which he became supervisory board chairman of Bayer.

Forty Years Afterward Bayer’s decision to market a product it knew to be contaminated to third-world countries had less to do with any racial-based “Final Solution” than it did preserving its profit margin. Although Bayer’s Cutter Biomedical division had started producing a new safer, heat-treated medication in 1984, it continued making and selling the old medication. The reason: there were still a number of fixed-price contracts, and production of the newer medication would cut into company profits. FDA Complicity? Even after the FDA discovered in May 1985 that Bayer was deliberately “steering the riskier [products] overseas” (according to the New York Times), it took no action. Instead, an official decided the problem should be “…quietly solved without alerting the Congress, the medical community and the public” (according to a company document). It is no secret that the FDA – a government agency charged with protecting the public interests – has been severely compromised by corporate money over the past generation, as has the media. Corporate money, power and greed has done more than affect the democratic process – it has become a cancer that threatens our very lives.

SHARE Acetylsalicylic - definition of Acetylsalicylic by The Free Dictionary Acetylsalicylic - definition of Acetylsalicylic by The Free Dictionary Related to Acetylsalicylic: acetylsalicylic acid as·pi·rin (ăs′pər-ĭn, -prĭn) n. pl. aspirin or as·pi·rins 1. A white, crystalline compound, C9H8O4, derived from salicylic acid and commonly used in tablet form to relieve pain and reduce fever and inflammation. It is also used as an antiplatelet agent. Also called acetylsalicylic acid. 2. A tablet of aspirin. [Originally a trademark.] (ˈæsprɪn) n, pl -rin or -rins 1. (Pharmacology) a white crystalline compound widely used in the form of tablets to relieve pain and fever, to reduce inflammation, and to prevent strokes. Formula: CH3COOC6H4COOH. Chemical name: acetylsalicylic acid 2.

(Pharmacology) a tablet of aspirin [C19: from German, from A(cetyl) + Spir(säure) spiraeic acid (modern salicylic acid) + -in; see also spiraea] as•pi•rin (ˈæs pər ɪn, -prɪn) n., pl. -rin, -rins. 1. a white, crystalline substance, C9H8O4, derivative of salicylic acid, used as an anti-inflammatory agent and to relieve pain and fever; acetylsalicylic acid. 2. a tablet of this. [1899; < German, orig. a trademark, =A(cetyl) acetyl + Spir(säure) salicylic acid (see spirea ) + -in -in 1] as·pi·rin (ăs′pər-ĭn, ăs′prĭn) A white crystalline compound derived from salicylic acid and used as a drug to relieve fever and pain. Also called acetylsalicylic acid. Did You Know? The forest may not look like a drugstore.

Nevertheless, plants have always provided humans with powerful medicine. For example, we no longer eat the bark of willow trees when we have headaches, but for thousands of years, people in pain did just that. About 100 years ago, scientists studying willow bark figured out how it could be used to make acetylsalicylic acid, better known as aspirin. Aspirin and willow bark get broken down in the stomach to supply us with the same powerful painkiller. Quinine, which people use to control the fevers of the disease malaria, originally came from the cinchona tree. Just recently, researchers developed a new cancer drug, taxol, from the needles of yew trees. In fact, about 45 percent of all cancer drugs are either natural products or slightly altered natural chemicals that scientists tinkered with to make more potent. Researchers still study traditional plant remedies in the hopes of finding even more medicines from nature. ThesaurusAntonymsRelated WordsSynonymsLegend:

Question: Acetylsalicylic Acid is better known by what Bayer trademark?
Answer: Aspirin