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Fitoterapia 81 (6): 627–31. (2010). doi:10.1016/j.fitote.2010.03.008. PMID 20227468. https://www.researchgate.net/publication/41942987 2016年5月15日閲覧. "the result of the acute toxicity test showed that the LD(50) of theacrine was 810.6 mg/kg (769.5-858.0mg/kg)."
↑ “Comparative toxicity of caffeine and aminophylline (theophylline ethylenediamine) in young and adult rats”. Biology of the Neonate 34 (1–2): 68–71. (1978). doi:10.1159/000241107. PMID 698326. "In adult rats, the LD50 of caffeine and aminophylline was the same after 24 h and after 1 week of observation: caffeine 265 mg/kg"
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