非相同末端結合
↑ Chen, X., & Tomkinson, A. E. (2011). Yeast nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining. The Journal of biological chemistry, 286 (6), 4931-4940. URL https://doi.org/10.1074/jbc.m110.195024
↑ van der Burg, M., Ijspeert, H., Verkaik, N. S., Turul, T., Wiegant, W. W., Morotomi-Yano, K., Mari, P.-O. O., Tezcan, I., Chen, D. J., Zdzienicka, M. Z., van Dongen, J. J., & van Gent, D. C. (2009). A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits artemis activation and nonhomologous end-joining. The Journal of clinical investigation, 119 (1), 91-98. URL https://doi.org/10.1172/jci37141
↑ Chistiakov, D. A., Voronova, N.
これまでにDNA-PKcs、LigIV、Artemis、XLF、XRCC4の遺伝子異常によって引き起こされる難病が知られている。
Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4. Mutation Research/DNA Repair, 433 (1), 53-58. URL https://doi.org/10.1016/s0921-8777(98)00063-9
↑ Tsai, C. J., Kim, S. A., & Chu, G. (2007). Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proceedings of the National Academy of Sciences of the United States of America, 104 (19), 7851-7856. URL https://doi.org/10.1073/pnas.0702620104
↑ Riballo, E., Woodbine, L., Stiff, T., Walker, S. A., Goodarzi, A. A., & Jeggo, P. A. (2009). XLF-cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation. Nucleic acids research, 37 (2), 482-492. URL https://doi.org/10.1093/nar/gkn957