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白血病阻止因子(はっけつびょうそしいんし、Leukemia inhibitory factor、略称: LIF)は、細胞の分化を阻害することによって細胞の成長に影響を与えるIL-6ファミリーのサイトカインの一種である。LIF量が低下した時に、細胞は分化する。