インスリノーマ
正常であれば、血糖が低下すると膵β細胞からのインスリン分泌が抑制され、グルカゴンを初めとする血糖値を上昇させるホルモンが分泌され、糖新生が刺激される。血糖値は常に80~100mg/dLに維持されるが、この腫瘍がある限り、分泌抑制に異常があり、低下してもインスリンの分泌が続き、それに伴って低血糖症状を惹き起こす。
↑ Diagnostic Difficulties in a Pediatric InsulinomaIngrith Miron, MD, PhD, Smaranda Diaconescu, MD, PhD, Gabriel Aprodu, MD, PhD, Ileana Ioniuc, MD, PhD, Mihai Radu Diaconescu, MD, PhD, and Lucian Miron, MD, PhD. doi:10.1097/MD.0000000000003045
1 2 3 Insulinoma: A Comprehensive Summary of Two CasesPankaj Sharma, Sonia Sharma, Shivani Kalhan, corresponding author Bhanu Pratap Singh, and Sonam Sharma. doi:10.7860/JCDR/2014/8694.4782
1 2 3 Diagnosis and Localization of Insulinoma after Negative Laparotomy by Hyperinsulinemic, Hypoglycemic Clamp and Intra-Aterial Calcium StimulationRobert A. Ritzel, Berend Isermann, Tobias Schilling, Hanns-Peter Knaebel, Markus W. Büchler, and Peter P. Nawroth. doi:10.1900/RDS.2004.1.42
1 2 3 4 Recurrent insulinoma in a 10-year-old boy with Down's syndromeNoman Ahmad,corresponding author Abdulmonem Mohammed Almutawa, Mohamed Ziyad Abubacker, Hossam Ahmed Elzeftawy, and Osama Abdullah Bawazir. doi:10.1530/EDM-16-0155
1 2 3 4 Paroxysmal dystonic choreoathetosis with symptomatic seizures secondary to hypoglycemia caused by insulinomaMeena Gupta, Amit Batra, Makarand Hirve, Debashish Chowdhury, Geeta A. Khwaja, and P. K. Mishra. doi:10.4103/0972-2327.91965
1 2 3 Insulinoma After Bariatric Surgery: Diagnostic Dilemma and Therapeutic ApproachesChristopher M. Mulla, MD, Alessandra Storino, MD, Eric U. Yee, MD, David Lautz, MD, Mandeep S. Sawnhey, MD, A.