須貝章弘
Sugai, A.; Kato, T.; Koyama, A.; Koike, Y.; Kasahara, S.; Konno, T.; Ishihara, T.; Onodera, O. (2018). “Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data”. Frontiers in Neuroscience 12 (28). doi:10.3389/fnins.2018.00028. PMID 29449800. https://www.frontiersin.org/articles/10.3389/fnins.2018.00028/full.
細胞内のTDP-43の動態をコンピュータ上でモデル化し、TDP-43の自己調節機構に関する仮説を提唱した。
Sugai, A.; Kato, T.; Koyama, A.; Koike, Y.; Konno, T.; Ishihara, T.; Onodera, O. (2019). “Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation”.