脳由来神経栄養因子
ncbi.nlm.nih.gov/pmc/articles/PMC4064707/. "Moreover, recent evidence suggests that myokines released by exercising muscles affect the expression of brain-derived neurotrophic factor synthesis in the dentate gyrus of the hippocampus, a finding that could lead to the identification of new and therapeutically important mediating factors. ... Studies have demonstrated the intensity of exercise training is positively correlated with BDNF plasma levels in young, healthy individuals (Ferris et al., 2007). Resistance exercise has also been shown to elevate serum BDNF levels in young individuals (Yarrow et al., 2010). Moreover, it has been shown that moderate levels of physical activity in people with AD significantly increased plasma levels of BDNF (Coelho et al., 2014).
J. Neurosci. 21 (17): 6706–17. PMID 11517260. http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=11517260.
↑ Ernfors P, Kucera J, Lee KF, Loring J, Jaenisch R (October 1995). “Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice”. Int. J. Dev. Biol. 39 (5): 799–807. PMID 8645564. http://www.intjdevbiol.com/paper.php?doi=8645564.
↑ MGI database: phenotypes for BDNF homozygous null mice. http://www.informatics.jax.org/searches/allele_report.cgi?_Marker_key=537&int:_Set_key=847156
↑ Szuhany KL, Bugatti M, Otto MW (October 2014). “A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor”.