ヒトヘルペスウイルス6
HHV-6のウイルス粒子がヒトの細胞に侵入する際には、補体系の制御に関わるCD46を受容体として利用している。CD46分子にはオルタナティブスプライシングによって少なくとも14種のアイソフォームが生じるが、その全てがHHV-6Aに結合しうる。CD46に結合するウイルス側のリガンドは、gH/gL/gQ1/gQ2から成る糖タンパク質複合体である。
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↑ Kofman, Alexander; Marcinkiewicz, Lucasz; Dupart, Evan; Lyshchev, Anton; Martynov, Boris; Ryndin, Anatolii; Kotelevskaya, Elena; Brown, Jay et al.