アザチオプリン
↑ Hiemstra TF et al. Mycophenolate Mofetil vs Azathioprine for Remission Maintenance in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Randomized Controlled Trial. JAMA. 2010;304(21):2381-2388
↑ 厚生労働省薬食審医薬品第一部会で2018年7月27日自己免疫性肝炎の適応追加について公知申請を了承した。
↑ NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease.J Gastroenterol. 2016 Jan;51(1):22-9.
↑ NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD.Pharmacogenomics J.