コンデンシン
↑ Green LC, Kalitsis P, Chang TM, Cipetic M, Kim JH, Marshall O, Turnbull L, Whitchurch CB, Vagnarelli P, Samejima K, Earnshaw WC, Choo KH, Hudson DF (2012). “Contrasting roles of condensin I and condensin II in mitotic chromosome formation”. J. Cell Sci. 125 (Pt6): 1591-1604. PMID 22344259.
↑ Saka Y, Sutani T, Yamashita Y, Saitoh S, Takeuchi M, Nakaseko Y, Yanagida M (1994). “Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis”. EMBO J. 13 (20): 4938-4952. PMID 7957061.
↑ Hudson DF, Vagnarelli P, Gassmann R, Earnshaw WC (2003). “Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes”. Dev. Cell 5 (2): 323-336. PMID 12919682.
最近では、コンデンシンの分子活性をもとに、分裂期染色体構築の数理モデリングとコンピュータ・シミュレーションが盛んに行われつつある。代表的なものとして、ループ押出し(loop extrusion)モデルをもとにした試み、コンデンシン結合部位の確率的な相互作用を仮定した試み、ループ形成とコンデンシン間相互作用を併せた試みが発表されている。
Cell 98 (2): 239-248. PMID 10428035.
↑ Hagstrom KA1, Holmes VF, Cozzarelli NR, Meyer BJ (2002). “C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis”. Genes Dev 16 (6): 729-742. PMID 11914278.
1 2 3 St-Pierre J, Douziech M, Bazile F, Pascariu M, Bonneil E, Sauvé V, Ratsima H, D'Amours D (2009). “Polo kinase regulates mitotic chromosome condensation by hyperactivation of condensin DNA supercoiling activity”. Mol Cell 120 (Pt 7): 1245-1255. PMID 19481522.
1 2 Kimura K, Hirano M, Kobayashi R, Hirano T (1998). “Phosphorylation and activation of 13S condensin by Cdc2 in vitro”. Science 282 (5388): 487-490.