プレグナンX受容体
PMID 9489701.
“The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions”. The Journal of Clinical Investigation 102 (5): 1016–23. (September 1998). doi:10.1172/JCI3703. PMC 508967. PMID 9727070. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC508967/.
“Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction”. Proceedings of the National Academy of Sciences of the United States of America 95 (21): 12208–13. (October 1998). Bibcode: 1998PNAS...9512208B. doi:10.1073/pnas.95.21.12208. PMC 22810. PMID 9770465. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC22810/.
“SXR, a novel steroid and xenobiotic-sensing nuclear receptor”.
プレグナンX受容体(プレグナンXじゅようたい、英: pregnane X receptor、略称: PXR)は、ヒトではNR1I2遺伝子によってコードされるタンパク質である。SXR(steroid and xenobiotic sensing nuclear receptor)、NR1I2(nuclear receptor subfamily 1, group I, member 2)の名称でも知られる。