エストラムスチン
(1988). PMID 3287598.
“Intracellular effects of estramustine (Estracyt/Emcyt)”. Prog. Clin. Biol. Res. 303: 169–75. (1989). PMID 2674983.
“Estramustine--a nitrogen mustard/steroid with antimicrotubule activity”. Pharmacol. Ther. 43 (3): 299–319. (1989). doi:10.1016/0163-7258(89)90012-0. PMID 2682681.
“Estramustine phosphate (Estracyt) in the treatment of prostatic carcinoma”. Int Urol Nephrol 21 (4): 393–7. (1989). doi:10.1007/BF02559635. PMID 2693392.
“Mechanisms of action and clinical uses of estramustine”. Cancer Invest. 8 (3–4): 375–80. (1990). doi:10.3109/07357909009012056. PMID 2207764.
“The present role of estramustine phosphate in advanced prostate cancer”. Prog. Clin. Biol. Res. 370: 323–41. (1991). PMID 1924466.
次の患者には禁忌である。
製剤成分、エストラジオールまたはナイトロジェンマスタードに過敏症の既往歴のある患者
血栓性静脈炎、脳血栓、肺塞栓などの血栓塞栓性障害、虚血などの重篤な冠血管疾患、またはその既往歴のある患者
重篤な肝障害のある患者
重篤な血液障害のある患者
消化性潰瘍のある患者
海外では体液貯留にも禁忌とされる。
pp. 249–256. doi:10.1007/978-981-10-7013-6_26. ISBN 978-981-10-7012-9
1 2 3 4 5 6 7 8 9 10 11 12 “Estramustine phosphate sodium. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer”. Drugs Aging 7 (1): 49–74. (July 1995). doi:10.2165/00002512-199507010-00006. PMID 7579781.
1 2 3 4 https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/018045s023lbl.pdf
1 2 “Chemotherapy with or without estramustine for treatment of castration-resistant prostate cancer: A systematic review and meta-analysis”. Medicine (Baltimore) 95 (39): e4801. (September 2016). doi:10.1097/MD.0000000000004801. PMC 5265899. PMID 27684806. https://www.ncbi.nlm.nih.
J. Urol. 12 (2): 166–72. (February 2005). doi:10.1111/j.1442-2042.2005.01004.x. PMID 15733111.
↑ Gate, Laurent; Tew, Kenneth D. (2011). “Alkylating Agents”. Cancer Management in Man: Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures. pp. 61–85. doi:10.1007/978-90-481-9704-0_4. ISBN 978-90-481-9703-3
↑ http://www.ilexmedical.com/files/PDF/Estradiol_ARC.pdf
↑ Muller (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 245, 454. ISBN 978-3-7692-2114-5. https://books.google.com/books?id=2HBPHmclMWIC&pg=PA245
↑ Thorsteinn Loftsson (25 January 2014). Drug Stability for Pharmaceutical Scientists. Academic Press. pp. 77–. ISBN 978-0-12-411562-0.
↑ “Estrogens in the treatment of prostate cancer”. J. Urol. 154 (6): 1991–8. (December 1995). doi:10.1016/S0022-5347(01)66670-9. PMID 7500443.
↑ “Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data”. Lancet Oncol. 8 (11): 994–1000. (2007). doi:10.1016/S1470-2045(07)70284-X. PMID 17942366.
↑ “Low-Dose Estramustine Phosphate and Concomitant Low-Dose Acetylsalicylic Acid in Heavily Pretreated Patients With Advanced Castration-Resistant Prostate Cancer”. Clin Genitourin Cancer 13 (5): 441–6. (October 2015). doi:10.1016/j.clgc.2015.03.004. PMID 25920994.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 “Clinical pharmacokinetics of estramustine phosphate”.
(2003). doi:10.1016/j.coph.2003.07.004. PMID 14644018.
1 2 “Parenteral estrogen versus total androgen ablation in the treatment of advanced prostate carcinoma: effects on overall survival and cardiovascular mortality. The Scandinavian Prostatic Cancer Group (SPCG)-5 Trial Study”. Urology 55 (3): 328–33. (2000). doi:10.1016/s0090-4295(99)00580-4. PMID 10699602.
↑ “Estramustine phosphate for preventing flare-up in luteinizing hormone-releasing hormone analogue depot therapy”. Eur. Urol. 27 (3): 192–5. (1995). doi:10.1159/000475159. PMID 7541359.
↑ “Endocrine treatment of prostate cancer”. J. Steroid Biochem. Mol. Biol. 92 (4): 287–95. (November 2004). doi:10.1016/j.jsbmb.2004.10.005. PMID 15663992.