yz2022/T2P-DownstreamNLP huggingface dataset:
Infection

Other microscopic procedures may also aid in identifying infectious agents. Almost all cells readily stain with a number of basic dyes due to the electrostatic attraction between negatively charged cellular molecules and the positive charge on the dye. A cell is normally transparent under a microscope, and using a stain increases the contrast of a cell with its background. Staining a cell with a dye such as Giemsa stain or crystal violet allows a microscopist to describe its size, shape, internal and external components and its associations with other cells. The response of bacteria to different staining procedures is used in the taxonomic classification of microbes as well. Two methods, the Gram stain and the acid-fast stain, are the standard approaches used to classify bacteria and to diagnosis of disease. The Gram stain identifies the bacterial groups Firmicutes and Actinobacteria, both of which contain many significant human pathogens. The acid-fast staining procedure identifies the Actinobacterial genera Mycobacterium and Nocardia.

Question: What do almost all cells readily stain with?
Answer: a number of basic dyes

Question: Why do cells easily stain with dyes?
Answer: electrostatic attraction

Question: What electronic charge do cellular molecules have?
Answer: negatively charged

Question: How many methods comprise standard approaches used to classify bacteria and diagnose disease?
Answer: Two

Question: What is Geimsa stain?
Answer: a dye
Punjab,_Pakistan

The fairs held at the shrines of Sufi saints are called urs. They generally mark the death anniversary of the saint. On these occasions devotees assemble in large numbers and pay homage to the memory of the saint. Soul inspiring music is played and devotees dance in ecstasy. The music on these occasions is essentially folk and appealing. It forms a part of the folk music through mystic messages. The most important urs are: urs of Data Ganj Buksh at Lahore, urs of Hazrat Sultan Bahu at Jhang, urs of Hazrat Shah Jewna at Jhang, urs of Hazrat Mian Mir at Lahore, urs of Baba Farid Ganj Shakar at Pakpattan, urs of Hazrat Bahaudin Zakria at Multan, urs of Sakhi Sarwar Sultan at Dera Ghazi Khan, urs of Shah Hussain at Lahore, urs of Hazrat Bulleh Shah at Kasur, urs of Hazrat Imam Bari (Bari Shah Latif) at Rawalpindi-Islamabad and urs of Shah Inayar Qadri (the murrshad of Bulleh Shah) in Lahore.

Question: Where is Zakria's shrine?
Answer: Multan

Question: What are urs?
Answer: fairs held at the shrines of Sufi saints
Infection

There is usually an indication for a specific identification of an infectious agent only when such identification can aid in the treatment or prevention of the disease, or to advance knowledge of the course of an illness prior to the development of effective therapeutic or preventative measures. For example, in the early 1980s, prior to the appearance of AZT for the treatment of AIDS, the course of the disease was closely followed by monitoring the composition of patient blood samples, even though the outcome would not offer the patient any further treatment options. In part, these studies on the appearance of HIV in specific communities permitted the advancement of hypotheses as to the route of transmission of the virus. By understanding how the disease was transmitted, resources could be targeted to the communities at greatest risk in campaigns aimed at reducing the number of new infections. The specific serological diagnostic identification, and later genotypic or molecular identification, of HIV also enabled the development of hypotheses as to the temporal and geographical origins of the virus, as well as a myriad of other hypothesis. The development of molecular diagnostic tools have enabled physicians and researchers to monitor the efficacy of treatment with anti-retroviral drugs. Molecular diagnostics are now commonly used to identify HIV in healthy people long before the onset of illness and have been used to demonstrate the existence of people who are genetically resistant to HIV infection. Thus, while there still is no cure for AIDS, there is great therapeutic and predictive benefit to identifying the virus and monitoring the virus levels within the blood of infected individuals, both for the patient and for the community at large.

Question: What is used in the treatment of AIDS?
Answer: AZT
Punjab,_Pakistan

The fairs held at the shrines of Sufi saints are called urs. They generally mark the death anniversary of the saint. On these occasions devotees assemble in large numbers and pay homage to the memory of the saint. Soul inspiring music is played and devotees dance in ecstasy. The music on these occasions is essentially folk and appealing. It forms a part of the folk music through mystic messages. The most important urs are: urs of Data Ganj Buksh at Lahore, urs of Hazrat Sultan Bahu at Jhang, urs of Hazrat Shah Jewna at Jhang, urs of Hazrat Mian Mir at Lahore, urs of Baba Farid Ganj Shakar at Pakpattan, urs of Hazrat Bahaudin Zakria at Multan, urs of Sakhi Sarwar Sultan at Dera Ghazi Khan, urs of Shah Hussain at Lahore, urs of Hazrat Bulleh Shah at Kasur, urs of Hazrat Imam Bari (Bari Shah Latif) at Rawalpindi-Islamabad and urs of Shah Inayar Qadri (the murrshad of Bulleh Shah) in Lahore.

Question: What genre of music is played at urs?
Answer: folk

Question: Where is Buksh's shrine?
Answer: Lahore
Infection

There is usually an indication for a specific identification of an infectious agent only when such identification can aid in the treatment or prevention of the disease, or to advance knowledge of the course of an illness prior to the development of effective therapeutic or preventative measures. For example, in the early 1980s, prior to the appearance of AZT for the treatment of AIDS, the course of the disease was closely followed by monitoring the composition of patient blood samples, even though the outcome would not offer the patient any further treatment options. In part, these studies on the appearance of HIV in specific communities permitted the advancement of hypotheses as to the route of transmission of the virus. By understanding how the disease was transmitted, resources could be targeted to the communities at greatest risk in campaigns aimed at reducing the number of new infections. The specific serological diagnostic identification, and later genotypic or molecular identification, of HIV also enabled the development of hypotheses as to the temporal and geographical origins of the virus, as well as a myriad of other hypothesis. The development of molecular diagnostic tools have enabled physicians and researchers to monitor the efficacy of treatment with anti-retroviral drugs. Molecular diagnostics are now commonly used to identify HIV in healthy people long before the onset of illness and have been used to demonstrate the existence of people who are genetically resistant to HIV infection. Thus, while there still is no cure for AIDS, there is great therapeutic and predictive benefit to identifying the virus and monitoring the virus levels within the blood of infected individuals, both for the patient and for the community at large.

Question: What could be done by understanding how the disease was transmitted?
Answer: resources could be targeted to the communities at greatest risk

Question: What is now commonly used to identify HIV in healthy people before the onset of the illnes?
Answer: Molecular diagnostics
Infection

Evidence of infection in fossil remains is a subject of interest for paleopathologists, scientists who study occurrences of injuries and illness in extinct life forms. Signs of infection have been discovered in the bones of carnivorous dinosaurs. When present, however, these infections seem to tend to be confined to only small regions of the body. A skull attributed to the early carnivorous dinosaur Herrerasaurus ischigualastensis exhibits pit-like wounds surrounded by swollen and porous bone. The unusual texture of the bone around the wounds suggests they were afflicted by a short-lived, non-lethal infection. Scientists who studied the skull speculated that the bite marks were received in a fight with another Herrerasaurus. Other carnivorous dinosaurs with documented evidence of infection include Acrocanthosaurus, Allosaurus, Tyrannosaurus and a tyrannosaur from the Kirtland Formation. The infections from both tyrannosaurs were received by being bitten during a fight, like the Herrerasaurus specimen.

Question: What profession finds evidence of infection in fossil remains to be interesting?
Answer: paleopathologists
Hunting

Archaeologist Louis Binford criticised the idea that early hominids and early humans were hunters. On the basis of the analysis of the skeletal remains of the consumed animals, he concluded that hominids and early humans were mostly scavengers, not hunters, and this idea is popular among some archaeologists and paleoanthropologists. Robert Blumenschine proposed the idea of confrontational scavenging, which involves challenging and scaring off other predators after they have made a kill, which he suggests could have been the leading method of obtaining protein-rich meat by early humans.

Question: What is Louis Binford's profession?
Answer: Archaeologist
Infection

Evidence of infection in fossil remains is a subject of interest for paleopathologists, scientists who study occurrences of injuries and illness in extinct life forms. Signs of infection have been discovered in the bones of carnivorous dinosaurs. When present, however, these infections seem to tend to be confined to only small regions of the body. A skull attributed to the early carnivorous dinosaur Herrerasaurus ischigualastensis exhibits pit-like wounds surrounded by swollen and porous bone. The unusual texture of the bone around the wounds suggests they were afflicted by a short-lived, non-lethal infection. Scientists who studied the skull speculated that the bite marks were received in a fight with another Herrerasaurus. Other carnivorous dinosaurs with documented evidence of infection include Acrocanthosaurus, Allosaurus, Tyrannosaurus and a tyrannosaur from the Kirtland Formation. The infections from both tyrannosaurs were received by being bitten during a fight, like the Herrerasaurus specimen.

Question: What do paleopathologists study?
Answer: occurrences of injuries and illness in extinct life forms

Question: What has been discovered in the bones of carnivorous dinosaurs?
Answer: Signs of infection

Question: What dinosaur's skull had pit-like wounds surrounded by swollen and porous bone?
Answer: Herrerasaurus ischigualastensis

Question: How did tyrannosaurs become infected?
Answer: being bitten during a fight
Hunting

Archaeologist Louis Binford criticised the idea that early hominids and early humans were hunters. On the basis of the analysis of the skeletal remains of the consumed animals, he concluded that hominids and early humans were mostly scavengers, not hunters, and this idea is popular among some archaeologists and paleoanthropologists. Robert Blumenschine proposed the idea of confrontational scavenging, which involves challenging and scaring off other predators after they have made a kill, which he suggests could have been the leading method of obtaining protein-rich meat by early humans.

Question: What idea did Binford take issue with?
Answer: that early hominids and early humans were hunters

Question: What idea did Blumenschine propose?
Answer: idea of confrontational scavenging

Question: What does confrontational scavenging involve doing to other predators after they've made a kill?
Answer: challenging and scaring off
Infection

The medical treatment of infectious diseases falls into the medical field of Infectious Disease and in some cases the study of propagation pertains to the field of Epidemiology. Generally, infections are initially diagnosed by primary care physicians or internal medicine specialists. For example, an "uncomplicated" pneumonia will generally be treated by the internist or the pulmonologist (lung physician). The work of the infectious diseases specialist therefore entails working with both patients and general practitioners, as well as laboratory scientists, immunologists, bacteriologists and other specialists.

Question: What medical field does the treatment of infectious diseases fall into?
Answer: field of Infectious Disease

Question: Disease propagation can fall under the purview of what field of study?
Answer: Epidemiology
Hunting

Archaeologist Louis Binford criticised the idea that early hominids and early humans were hunters. On the basis of the analysis of the skeletal remains of the consumed animals, he concluded that hominids and early humans were mostly scavengers, not hunters, and this idea is popular among some archaeologists and paleoanthropologists. Robert Blumenschine proposed the idea of confrontational scavenging, which involves challenging and scaring off other predators after they have made a kill, which he suggests could have been the leading method of obtaining protein-rich meat by early humans.

Question: Who is the archaeologist that does not believe early humans were hunters?
Answer: Louis Binford
Infection

The medical treatment of infectious diseases falls into the medical field of Infectious Disease and in some cases the study of propagation pertains to the field of Epidemiology. Generally, infections are initially diagnosed by primary care physicians or internal medicine specialists. For example, an "uncomplicated" pneumonia will generally be treated by the internist or the pulmonologist (lung physician). The work of the infectious diseases specialist therefore entails working with both patients and general practitioners, as well as laboratory scientists, immunologists, bacteriologists and other specialists.

Question: Who tends to initially diagnose an infection?
Answer: primary care physicians or internal medicine specialists

Question: Who works with both patients and general practitioners to identify a disease?
Answer: infectious diseases specialist

Question: What is the non-medical mumbo jumbo term for pulmonologist?
Answer: lung physician
Hunting

Archaeologist Louis Binford criticised the idea that early hominids and early humans were hunters. On the basis of the analysis of the skeletal remains of the consumed animals, he concluded that hominids and early humans were mostly scavengers, not hunters, and this idea is popular among some archaeologists and paleoanthropologists. Robert Blumenschine proposed the idea of confrontational scavenging, which involves challenging and scaring off other predators after they have made a kill, which he suggests could have been the leading method of obtaining protein-rich meat by early humans.

Question: Louis Binford concluded what based on skeletal remains of consumed animals?
Answer: hominids and early humans were mostly scavengers

Question: What did Robert Blumenschine propose?
Answer: confrontational scavenging

Question: Louis Binford's idea is popular among whom?
Answer: archaeologists and paleoanthropologists
Hunting

Furthermore, evidence exists that hunting may have been one of the multiple environmental factors leading to extinctions of the holocene megafauna and their replacement by smaller herbivores. North American megafauna extinction was coincidental with the Younger Dryas impact event, possibly making hunting a less critical factor in prehistoric species loss than had been previously thought. However, in other locations such as Australia, humans are thought to have played a very significant role in the extinction of the Australian megafauna that was widespread prior to human occupation.

Question: What was the North American megafauna extinction coincidental with?
Answer: Younger Dryas impact event

Question: What does evidence suggest hunting may have been a factor in the extinction of?
Answer: holocene megafauna

Question: What are humans thought to have played a significant role in, in Australia?
Answer: extinction of the Australian megafauna

Question: When was Australian's megafauna widespread?
Answer: prior to human occupation

Question: What is thought to have played a significant role in the extinction of the Australian megafauna?
Answer: humans

Question: What replaced the holocene megafauna?
Answer: smaller herbivores

Question: What event was coincidental with the North American megafauna extinction? 
Answer: Younger Dryas impact event

Question: What along with multiple environmental factors led to the extinction of the holocene megafauna?
Answer: hunting
Hunting

Archaeologist Louis Binford criticised the idea that early hominids and early humans were hunters. On the basis of the analysis of the skeletal remains of the consumed animals, he concluded that hominids and early humans were mostly scavengers, not hunters, and this idea is popular among some archaeologists and paleoanthropologists. Robert Blumenschine proposed the idea of confrontational scavenging, which involves challenging and scaring off other predators after they have made a kill, which he suggests could have been the leading method of obtaining protein-rich meat by early humans.

Question: Confrontational scavenging involves doing what to other predators?
Answer: challenging and scaring off
Hunting

Even as animal domestication became relatively widespread and after the development of agriculture, hunting was usually a significant contributor to the human food supply. The supplementary meat and materials from hunting included protein, bone for implements, sinew for cordage, fur, feathers, rawhide and leather used in clothing. Man's earliest hunting weapons would have included rocks, spears, the atlatl, and bows and arrows. Hunting is still vital in marginal climates, especially those unsuited for pastoral uses or agriculture.[citation needed] For example, Inuit people in the Arctic trap and hunt animals for clothing and use the skins of sea mammals to make kayaks, clothing, and footwear.

Question: What was a significant contributor to the human food supply?
Answer: hunting

Question: What did the supplementary meat from hunting include?
Answer: protein, bone for implements, sinew for cordage, fur, feathers, rawhide and leather

Question: What was the leather from hunting used for?
Answer: clothing

Question: Where is hunting still vital?
Answer: marginal climates

Question: Rocks and spears are examples of some of man's earliest what?
Answer: hunting weapons
Hunting

In most parts of medieval Europe, the upper class obtained the sole rights to hunt in certain areas of a feudal territory. Game in these areas was used as a source of food and furs, often provided via professional huntsmen, but it was also expected to provide a form of recreation for the aristocracy. The importance of this proprietary view of game can be seen in the Robin Hood legends, in which one of the primary charges against the outlaws is that they "hunt the King's deer". In contrast, settlers in Anglophone colonies gloried democratically in hunting for all.

Question: What did Anglophone settles take gloried pride in?
Answer: democratically in hunting for all
Hunting

Even as animal domestication became relatively widespread and after the development of agriculture, hunting was usually a significant contributor to the human food supply. The supplementary meat and materials from hunting included protein, bone for implements, sinew for cordage, fur, feathers, rawhide and leather used in clothing. Man's earliest hunting weapons would have included rocks, spears, the atlatl, and bows and arrows. Hunting is still vital in marginal climates, especially those unsuited for pastoral uses or agriculture.[citation needed] For example, Inuit people in the Arctic trap and hunt animals for clothing and use the skins of sea mammals to make kayaks, clothing, and footwear.

Question: Hunt was a significant contributor to what?
Answer: human food supply

Question: Why is hunting still vital in marginal climates?
Answer: unsuited for pastoral uses or agriculture

Question: Where is hunting still vital?
Answer: marginal climates

Question: How are the skins of sea mammals useful for people in the Arctic trap?
Answer: make kayaks, clothing, and footwear
Infection

The clearance of the pathogens, either treatment-induced or spontaneous, it can be influenced by the genetic variants carried by the individual patients. For instance, for genotype 1 hepatitis C treated with Pegylated interferon-alpha-2a or Pegylated interferon-alpha-2b (brand names Pegasys or PEG-Intron) combined with ribavirin, it has been shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in the treatment-induced clearance of the virus. This finding, originally reported in Nature, showed that genotype 1 hepatitis C patients carrying certain genetic variant alleles near the IL28B gene are more possibly to achieve sustained virological response after the treatment than others. Later report from Nature demonstrated that the same genetic variants are also associated with the natural clearance of the genotype 1 hepatitis C virus.

Question: What can the clearance of pathogens be influenced by in an individual?
Answer: genetic variants
Hunting

In most parts of medieval Europe, the upper class obtained the sole rights to hunt in certain areas of a feudal territory. Game in these areas was used as a source of food and furs, often provided via professional huntsmen, but it was also expected to provide a form of recreation for the aristocracy. The importance of this proprietary view of game can be seen in the Robin Hood legends, in which one of the primary charges against the outlaws is that they "hunt the King's deer". In contrast, settlers in Anglophone colonies gloried democratically in hunting for all.

Question: Who provided the game obtained in feudal territory?
Answer: professional huntsmen
Infection

The top three single agent/disease killers are HIV/AIDS, TB and malaria. While the number of deaths due to nearly every disease have decreased, deaths due to HIV/AIDS have increased fourfold. Childhood diseases include pertussis, poliomyelitis, diphtheria, measles and tetanus. Children also make up a large percentage of lower respiratory and diarrheal deaths. In 2012, approximately 3.1 million people have died due to lower respiratory infections, making it the number 4 leading cause of death in the world.

Question: Who makes up a large percentage of diarrheal deaths?
Answer: Children
Infection

The clearance of the pathogens, either treatment-induced or spontaneous, it can be influenced by the genetic variants carried by the individual patients. For instance, for genotype 1 hepatitis C treated with Pegylated interferon-alpha-2a or Pegylated interferon-alpha-2b (brand names Pegasys or PEG-Intron) combined with ribavirin, it has been shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in the treatment-induced clearance of the virus. This finding, originally reported in Nature, showed that genotype 1 hepatitis C patients carrying certain genetic variant alleles near the IL28B gene are more possibly to achieve sustained virological response after the treatment than others. Later report from Nature demonstrated that the same genetic variants are also associated with the natural clearance of the genotype 1 hepatitis C virus.

Question: What is the brand name Pegasys for?
Answer: Pegylated interferon-alpha-2b