ABSTRACT Histopathological image retrieval is a key technology for computer-aided diagnosis. However, patients are reluctant to reveal their privacy in histopathological image retrieval. In order to further improve the effectiveness and safety of histopathological image retrieval, this paper proposes a new histopathological retrieval scheme based on asymmetric residual hash (ARH) and DNA coding techniques. In this paper, we first present a novel ARH for histopathological image retrieval to improve the effectiveness of histopathological search scheme, and then we use the 5-D hyperchaotic system to protect patient privacy. Specifically, the contribution consists of four aspects: 1) A histopathology ciphertext domain search scheme was proposed to improve the performance of computer-aided diagnosis. 2) An asymmetric approach was implemented to process histopathological query points and database points, and a novel asymmetric residual hash algorithm was first proposed to improve the accuracy and speed of histopathological image retrieval. 3) The 5-D hyperchaotic system and DNA coding technique are applied to histopathological image retrieval to protect patient privacy. 4) The loss function is constructed and optimized to learn network parameters and hash codes. The simulation experiment was performed on three datasets (Kimia Path24, Kimia Path960, and Malaria), and the results proved the effectiveness of the ARH algorithm. In addition, our proposed search method can resist common types of attacks during histopathological data transmission. Specifically, the MAP of the ARH is 0.9678 on the KIMIA Path24 with the value of hyperparameter is 125 and the length of hash code is 32. The MAP of the ARH is 0.966 on the KIMIA Path960 with the value of hyperparameter is 225 and the length of hash code is 32. The MAP of the ARH is 0.9482 on the Malaria with the value of hyperparameter is 10 and the length of hash code is 24. INDEX TERMS Histopathological image retrieval, asymmetric residual hash, computer-aided diagnosis, patient privacy, DNA coding.
Cheng et al. REF proposed a deep hashing algorithm based on ResNet 50 to perform image retrieval and classification tasks.
Histopathological Image Retrieval Based on Asymmetric Residual Hash and DNA Coding
IEEE Access
IEEE Access
Computer Science