The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the similarity between Disease Ontology (DO) terms and provide the significance of the similarity score. Disease similarity has drawn more and more attention in exploring the molecular mechanisms underlying human complex diseases [1] [2] [3] [4] [5]
In REF , an online system called DisSim was introduced for exploring similar diseases.
DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs
Scientific Reports
Scientific Reports
Computer Science Medicine