芬太尼类物质

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芬太尼类物质（fentanyl analogs，fentalogs）是指芬太尼的类似物，满足以下条件之一：

（1）丙酰基（用红色标注）被其他酰基替代。

（2）与氮原子直接相连的苯基（用蓝色标注）被任何取代或未取代的单环芳香基团替代。

（3）哌啶环（用橙色标注）上存在烷基、烯基、烷氧基、酯基、醚基、羟基、卤素、卤代烷基、氨基及硝基等取代基。

（4）苯乙基（用绿色标注）被使用除氢原子外的任意基团替代。

## 列表

### 满足一个条件

化学结构｜常用名｜化学名｜化学式｜CAS号｜满足条件

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｜Thiophenylfentanyl(Thiofuranylfentanyl)｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-ylthiophene-2-carboxamide｜C24H26N2OS｜2306823-38-9｜（1）

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｜3-呋喃基芬太尼(3FUF)｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-ylfuran-3-carboxamide｜C24H26N2O2｜101343-82-2｜（1）

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｜2-呋喃基芬太尼(Fu-F, FUF)｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-ylfuran-2-carboxamide｜C24H26N2O2｜101345-66-8｜（1）

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｜2-四氢呋喃芬太尼｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-yloxolane-2-carboxamide｜C24H30N2O2｜2142571-01-3｜（1）

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｜环戊基芬太尼｜N-phenyl-N-1-(2-phenylethyl)piperidin-4-ylcyclopentanecarboxamide｜C25H32N2O｜2088918-01-6｜（1）

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｜环丁基芬太尼｜N-1-(2-Phenylethyl)piperidin-4-yl-N-phenylcyclobutanecarboxamide｜C24H30N2O｜2306827-55-2｜（1）

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｜环丙基芬太尼｜N-1-(2-Phenylethyl)piperidin-4-yl-N-phenylcyclopropanecarboxamide｜C23H28N2O｜1169-68-2｜（1）

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｜四甲基环丙基芬太尼｜2,2,3,3-Tetramethyl-N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopropane-1-carboxamide｜C27H36N2O｜2309383-11-5｜（1）

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｜巴豆酰芬太尼｜N-Phenyl-N-1-(2-phenylethyl)-4-piperidinyl-2-butenamide｜C23H28N2O｜760930-59-4｜（1）

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｜二甲烯丙酰芬太尼｜N-phenyl-N-1-(2-phenylethyl)-4-piperidinyl-3-methylbut-2-enamide｜C24H30N2O｜2630378-28-6｜（1）

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｜丙烯酰芬太尼｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-ylprop-2-enamide｜C22H26N2O｜82003-75-6｜（1）

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｜甲氧乙酰基芬太尼(MAF)｜2-Methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide｜C22H28N2O2｜101345-67-9｜（1）

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｜乙氧乙酰基芬太尼｜2-ethoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide｜C23H30N2O2｜778534-59-1｜（1）

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｜乙酰芬太尼｜N-(1-Phenethylpiperidin-4-yl)-N-phenylacetamide｜C21H26N2O｜3258-84-2｜（1）

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｜异丁酰芬太尼｜2-methyl-N-phenyl-N-1-(1-phenylpropan-2-yl)piperidin-4-ylpropanamide｜C23H30N2O｜119618-70-1｜（1）

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｜丁酰芬太尼(Bu-F, BUF)｜N-(1-(2-Phenylethyl)-4-piperidinyl)-N-phenylbutyramide｜C23H30N2O｜1169-70-6｜（1）

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｜戊酰芬太尼(VF)｜N-(1-(2-Phenylethyl)-4-piperidinyl)-N-phenylpentylamide｜C24H32N2O｜122882-90-0｜（1）

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｜Fentanyl carbamate｜ethyl N-phenyl-N-1-(2-phenylethyl)piperidin-4-ylcarbamate｜C22H28N2O2｜1465-20-9｜（1）

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｜脲芬太尼Ureafentanyl｜N,N-dimethyl-N'-phenyl-N'-1-(2-phenylethyl)-4-piperidinyl-urea｜C22H29N3O｜1443-50-1｜（1）

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｜Benzoylfentanyl｜N-(1-Phenethylpiperidin-4-yl)-N-phenylbenzamide｜C26H28N2O｜2309383-15-9｜（1）

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｜3-Phenylpropanoylfentanyl｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-yl-3-phenylpropanamide｜C28H32N2O｜79279-02-0｜（1）

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｜Benzodioxolefentanyl｜N-Phenyl-N-1-(2-phenylethyl)piperidin-4-yl-2H-1,3-benzodioxole-5-carboxamide｜C27H28N2O3｜2306823-01-6｜（1）

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｜Paramethylfentanyl (p-MF)｜N-(4-methylphenyl)-N-1-(2-phenylethyl)piperidin-4-ylpropanamide｜C23H30N2O｜1838-67-1｜（2）

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｜4-Fluorofentanyl｜N-(4-fluorophenyl)-N-1-(2-phenylethyl)piperidin-4-ylpropanamide｜C22H27FN2O｜90736-23-5｜（2）

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｜meta-fluorofentanyl｜N-(3-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-propanamide｜C22H27FN2O｜90736-22-4｜（2）

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｜3-Methylfentanyl (3-MF)｜N-(3-methyl-1-phenethyl-4-piperidyl)-N-phenyl-propanamide｜C23H30N2O｜42045-86-3｜（3）

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｜2,5-Dimethylfentanyl｜N-2,5-Dimethyl-1-(2-phenylethyl)piperidin-4-yl-N-phenylpropanamide｜C24H32N2O｜42045-97-6｜（3）

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｜3-烯丙基芬太尼｜N-(3S,4R)-1-Phenethyl-3-prop-2-enylpiperidin-4-yl-N-phenylpropanamide｜C25H32N2O｜82208-84-2｜（3）

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｜3-Fluorofentanyl(NFEPP)｜N-(3-Fluoro-1-phenethylpiperidin-4-yl)-N-phenylpropionamide｜C22H27FN2O｜1422952-84-8｜（3）

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｜Tetramethylfentanyl｜N-(2,2,6,6-tetramethyl-1-phenethyl-4-piperidyl)-N-phenyl-propanamide｜C26H36N2O｜（3）

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｜4-Phenylfentanyl｜N-Phenyl-N-4-phenyl-1-(2-phenylethyl)piperidin-4-ylpropanamide｜C28H32N2O｜120448-97-7｜（3）

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｜卡芬太尼｜Methyl 1-(2-phenylethyl)-4-phenyl(propanoyl)aminopiperidine-4-carboxylate｜C24H30N2O3｜59708-52-0｜（3）

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｜乙基卡芬太尼｜Ethyl 1-(2-phenylethyl)-4-phenyl(propanoyl)aminopiperidine-4-carboxylate｜C25H32N2O3｜（3）

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｜Q125760580｜N-cycloheptyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxamide｜C30H41N3O2｜PubChem CID：77461241｜（3）

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｜MP135｜N-42-(3-fluorophenyl)ethylcarboxamido1-(2-phenylethyl)piperidin-4-yl-N-benzylpropanamide｜C32H38FN3O2｜2677687-49-7｜（3）

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｜噻吩甲基芬太尼｜N-phenyl-N-{1-(thiophen-2-ylmethyl)piperidin-4-ylmethyl}propanamide｜C19H24N2OS｜122861-39-6盐酸盐：117332-93-1｜（4）

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｜苄基芬太尼｜N-(1-Benzylpiperidin-4-yl)-N-phenylpropanamide｜C21H26N2O｜1474-02-8｜（4）

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｜高芬太尼(N-phenylpropylnorfentanyl) ｜N-phenyl-N-1-(3-phenylpropyl)piperidin-4-ylpropanamide｜C23H30N2O｜59708-54-2｜（4）

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｜4"-Fluorofentanyl｜N-1-2-(4-Fluorophenyl)ethyl-4-piperidinyl-N-phenylpropanamide｜C22H27FN2O｜2748343-99-7｜（4）

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｜阿法甲基芬太尼 (AMF)｜N-phenyl-N-1-(1-phenylpropan-2-yl)-4-piperidylpropanamide｜C23H30N2O｜79704-88-4｜（4）

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｜阿法甲基硫代芬太尼｜N-Phenyl-N-1-(1-thiophen-2-ylpropan-2-yl)-4-piperidylpropanamide｜C21H28N2OS｜103963-66-2｜（4）

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｜α-Methyl-β-hydroxyfentanyl｜N-1-(1-hydroxy-1-phenylpropan-2-yl)piperidin-4-yl-N-phenylpropanamide｜C23H30N2O2｜PubChem CID：24843770｜（4）

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｜β-Methylfentanyl｜N-Phenyl-N-1-(2-phenylpropyl)piperidin-4-ylpropanamide｜C23H30N2O｜79146-56-8｜（4）

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｜倍他羟基芬太尼β-Hydroxyfentanyl｜N-1-(2-Hydroxy-2-phenylethyl)piperidin-4-yl-N-phenylpropanamide｜C22H28N2O2｜78995-10-5｜（4）

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｜β-Hydroxythiofentanyl｜N1-2-Hydroxy-2-(thiophen-2-yl)ethylpiperidin-4-ylN-phenylpropanamide｜C20H26N2O2S｜1474-34-6｜（4）

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｜2-Benzofuranylethyl-alpha-methylfentanyl｜N-(1-1-(1-Benzofuran-2-yl)-2-propanyl-4-piperidinyl)-N-phenylpropanamide｜（4）

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｜trans-phenylcyclopropyl-norfentanyl｜1-(trans-2-Phenylcyclopropyl)-4-(N-propionylanilino)piperidine｜C23H28N2O｜102504-49-4｜（4）

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｜Furanylethylfentanyl (FUEF)｜N-1-2-(2-furanyl)ethyl-4-piperidinyl-N-phenyl-propanamide｜C20H26N2O2｜802544-02-1｜（4）

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｜Pyridylfentany｜N-phenyl-N-1-(2-pyridin-4-ylethyl)piperidin-4-ylpropanamide｜C21H27N3O｜1443-41-0｜（4）

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｜N-(MDA)-fentanyl｜N-(1-(1-(benzod1,3dioxol-5-yl)propan-2-yl)piperidin-4-yl)-N-phenylpropionamide｜C24H30N2O3｜2843634-52-4｜（4）

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｜Q116482976｜N-(1-(2-(2,5-dimethoxy-4-bromophenyl)ethyl)piperidin-4-yl)-N-phenylpropionamide｜C24H31BrN2O3｜PubChem CID：165361468｜（4）

### 满足多个条件

化学结构｜常用名｜化学名｜化学式｜CAS号｜满足条件

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｜2-Methylmethoxyacetylfentanyl｜N-(2-Methylphenyl)-N-1-(2-phenylethyl)-4-piperidinyl-2-methoxyacetamide｜C23H30N2O2｜2748485-22-3｜（1）（2）

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｜2-Fluoroacrylfentanyl｜N-(2-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-propen-2-amide｜C22H25FN2O｜2309383-09-1｜（1）（2）

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｜2-Fluorobutyrfentanyl (o-FBF)｜N-(2-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-butanamide｜C23H29FN2O｜2163847-76-3｜（1）（2）

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｜2-Fluoroisobutyrfentanyl (o-FIBF)｜N-(2-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-2-methylpropanamide｜C23H29FN2O｜2351142-33-9｜（1）（2）

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｜2-Methylacetylfentanyl (o-MAF)｜N-(2-Methylphenyl)-N-1-(2-phenylethyl)-4-piperidinyl-acetamide｜C22H28N2O｜90736-11-1｜（1）（2）

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｜2,2'-Difluorofentanyl｜N-(2-Fluorophenyl)-N-1-(2-2-fluorophenylethyl)-4-piperidinyl-propanamide｜C22H26F2N2O｜2748343-87-3｜（2）（4）

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｜3-甲基丁酰芬太尼3-Methylbutyrfentanyl｜N-3-Methyl-1-(2-phenylethyl)piperidin-4-yl-N-phenylbutanamide｜C24H32N2O｜97605-09-9｜（1）（3）

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｜3-Methylcrotonylfentanyl｜N-Phenyl-N-1-(2-phenylethyl)-4-(3-methylpiperidin-1-yl)-2-butenamide｜C24H30N2O｜144480-29-5｜（1）（3）

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｜p-Methylcrotonylfentanyl｜N-(4-methylphenyl)-N-1-(2-phenylethyl)-4-(piperidin-1-yl)-2-butenamide｜C24H30N2O｜2734344-10-4｜（1）（2）

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｜3-Methylfuranylfentanyl (3MFUF, TMFUF)｜N-Phenyl-N-3-methyl-1-(2-phenylethyl)piperidin-4-ylfuran-2-carboxamide｜C25H28N2O2｜（1）（3）

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｜3-甲基硫代芬太尼3-Methylthiofentanyl｜N3-Methyl-1-2-(2-thienyl)ethylpiperidin-4-ylN-phenylpropanamide｜C21H28N2OS｜86052-04-2｜（3）（4）

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｜对氟丁酰芬太尼4-Fluorobutyrfentanyl（4-FBF）｜N-(4-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-butanamide｜C23H29FN2O｜244195-31-1｜（1）（2）

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｜4-Chloroisobutyrylfentanyl (4-CIBF) ｜2-Methyl-N-(4-chlorophenyl)-N-1-(1-phenylpropan-2-yl)piperidin-4-ylpropanamide｜244195-34-4｜（1）（2）

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｜4-Fluoroisobutyrfentanyl (4-FIBF)｜N-(4-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-isobutanamide｜244195-32-2｜（1）（2）

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｜para-fluorofuranylfentanyl (p-F-Fu-F)｜N-(1-phenethylpiperidin-4-yl)-N-(4-fluorophenyl)furan-2-carboxamide｜1802489-71-9｜（1）（2）

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｜para-chlorofuranylfentanyl (p-Cl-Fu-F)｜N-(1-phenethylpiperidin-4-yl)-N-(4-chlorophenyl)furan-2-carboxamide｜（1）（2）

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｜ortho-methylfuranylfentanyl (o-Me-Fu-F)｜N-(1-phenethylpiperidin-4-yl)-N-(o-tolyl)furan-2-carboxamide｜2309383-07-9｜（1）（2）

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｜ortho-methoxyfuranylfentanyl (o-MeO-Fu-F)｜N-(1-phenethylpiperidin-4-yl)-N-(2-methoxyphenyl)furan-2-carboxamide｜101343-50-4｜（1）（2）

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｜ortho-isopropylfuranylfentanyl (o-iPr-Fu-F)｜N-(1-phenethylpiperidin-4-yl)-N-(2-isopropylphenyl)furan-2-carboxamide｜（1）（2）

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｜4-Methoxybutyrfentanyl｜N-(4-Methoxyphenyl)-N-1-(2-phenylethyl)-4-piperidinyl-butanamide｜2088842-68-4｜（1）（2）

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｜para-Hydroxy‐butyrylfentanyl ｜N-(4-hydroxyphenyl)-N-1-(2-phenylethyl)-4-piperidinyl-butanamide｜（1）（2）

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｜4"-Fluoro-o-fluoro-3-methylfentanyl｜N-(2-fluorophenyl)-N-1-2-(4-fluorophenyl)ethyl-3-methylpiperidin-4-ylpropanamide｜（2）（3）（4）

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｜4-Methyl-methoxyacetylfentanyl (4-Me-MAF)｜N-(4-Methylphenyl)-N-1-(2-phenylethyl)-4-piperidinyl-2-methoxyacetamide｜（1）（2）

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｜4-甲苯乙基乙酰芬太尼4-Methylphenethylacetylfentanyl｜N-1-2-(4-Methylphenyl)ethyl-4-piperidinyl-N-phenylacetamide｜C22H28N2O｜90736-15-5盐酸盐：1071703-95-1｜（1）（4）

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｜α-甲基乙酰芬太尼Alphamethylacetylfentanyl｜N-Phenyl-N-1-(1-phenylpropan-2-yl)-4-piperidylacetamide｜C22H28N2O｜101860-00-8｜（1）（4）

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｜α-Methylbutyrfentanyl｜N-phenyl-N-1-(1-phenylpropan-2-yl)-4-piperidylbutanamide｜C24H32N2O｜244195-36-6｜（1）（4）

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｜阿芬太尼alfentanil｜N1-2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl-4-(methoxymethyl)piperidin-4-ylN-phenylpropanamide｜C21H32N6O3｜71195-58-9｜（3）（4）

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｜BDBM50223545 (Berger Fentanyl) ｜1-2-(2-phenylethyl)-3,4,4a,9b-tetrahydro-1H-pyrido4,3-bindol-5-ylpropan-1-one｜（2）（3）

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｜β-Hydroxy-4-methylfentanyl｜N-1-(2-hydroxy-2-phenylethyl)-4-methylpiperidin-4-yl-N-phenylpropanamide｜（3）（4）

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｜Brorphine｜11-1-(4-bromophenyl)ethylpiperidin-4-yl1,3-dihydro-2H-benzimidazol-2-one｜C20H22BrN3O｜2244737-98-0｜（1）（2）（4）

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｜Brifentanyl｜N-(3R,4S)-1-2-(4-Ethyl-5-oxotetrazol-1-yl)ethyl -3-methylpiperidin-4-yl-N-(2-fluorophenyl)-2-methoxyacetamide｜C20H29FN6O3｜101345-71-5｜（1）（2）（3）（4）

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｜Q83084477｜Methyl 1-benzyl-4-phenyl(propanoyl)aminopiperidine-4-carboxylate｜C23H28N2O3｜61085-72-1｜（3）（4）

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｜EAZ-91-05, Psicofentanil｜(quinuclidin-3-yl) 4-phenyl(propanoyl)amino-1-2-(indol-3-yl)ethylpiperidine-4-carboxylate｜C32H40N4O3

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｜异芬太尼｜N-(1-Benzyl-3-methylpiperidin-4-yl)-N-phenylpropanamide｜C22H28N2O｜79278-40-3

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｜Fentanyl azepane｜N-phenyl-N-1-(2-phenylethyl)azepan-4-ylpropanamide

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｜Furanylbenzylfentanyl｜N-Phenyl-N-(1-benzylpiperidin-4-yl)furan-2-carboxamide｜497240-21-8

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｜Indolylethylfentanyl｜N-(1-2-(1H-indol-3-yl)ethyl-4-piperidinyl)-N-phenyl-propanamide｜58399-46-5

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｜IQMF-4｜N-1-(2-Phenylethyl)piperidin-4-yl-N-(1-phenylpyrazol-3-yl)prop-2-enamide｜497100-48-8

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｜洛芬太尼｜methyl (3S,4R)-3-methyl-1-(2-phenylethyl)-4-phenyl(propionyl)aminopiperidine-4-carboxylate｜C25H32N2O3｜61380-40-3

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｜N-甲基降卡芬太尼（R-32395）｜methyl 1-methyl-4-(N-phenylpropanamido)piperidine-4-carboxylate｜C17H24N2O3｜59708-50-8｜（3）（4）

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｜Meta-fluoro-methoxyacetylfentanyl｜2-Methoxy-N-(1-phenethylpiperidin-4-yl)-N-(3-fluorophenyl)acetamide｜2306825-32-9

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｜4-(Methylthiazolyl)-pyrazolylethylfentanyl｜1-2-(1H-pyrazol-1-yl)ethyl-4-(4-methylthiazol-2-yl)-4-(N-phenylpropionamido)piperidine｜120070-51-1

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｜Mirfentanyl｜N-1-(2-Phenylethyl)piperidin-4-yl-N-pyrazin-2-yl-2-furamide｜117523-47-4

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｜奥芬太尼｜N-(2-Fluorophenyl)-2-methoxy-N-1-(2-phenylethyl)piperidin-4-ylacetamide｜C22H27FN2O2｜101343-69-5

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｜羟甲芬太尼｜N-1-(2-hydroxy-2-phenylethyl)-3-methylpiperidin-4-yl-N-phenylpropanamide｜C23H30N2O2｜78995-14-9

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｜羟甲卡芬太尼｜methyl 1-(2-hydroxy-2-phenylethyl)-3-methyl-4-(N-propanoylanilino)piperidine-4-carboxylate

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｜4"-Fluoroohmefentanyl｜methyl 1-2-hydroxy-2-(4-fluorophenyl)ethyl-3-methyl-4-(N-propanoylanilino)piperidine-4-carboxylate

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｜4"-Fluoro-ohlofentanyl｜methyl 1‐2‐(4‐fluorophenyl)‐2‐hydroxyethyl‐3‐methyl‐4‐(N‐phenylpropanamido)piperidine‐4‐carboxylate

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｜Orthofluorofentanyl｜N-(2-Fluorophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-propanamide｜910616-29-4

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｜p-Bromofentanyl｜N-(4-bromophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-propanamide｜117994-23-7

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｜p-Nitrofentanyl ｜N-(4-Nitrophenyl)-N-1-(2-phenylethyl)-4-piperidinyl-propanamide

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｜Parafluoroisobutyrylbenzylfentanyl｜N-(1-benzylpiperidin-4-yl)methyl-N-(4-fluorophenyl)-2-methylpropanamide

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｜4-Fluorocyclopropylbenzylfentanyl｜N-(1-benzylpiperidin-4-yl)-N-(4-fluorophenyl)cyclopropanecarboxamide｜2344231-47-4

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｜Pivaloylfentanyl｜2,2-dimethyl-N-phenyl-N-1-(2-phenylethyl)piperidin-4-ylpropanamide

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｜Pyrrole-fentanyl ｜N-1-(2-Phenylethyl)piperidin-4-yl-N-pyrrol-1-ylpropanamide

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｜R-30490｜N-4-(Methoxymethyl)-1-(2-phenylethyl)piperidin-4-yl-N-phenylpropanamide｜60618-49-7

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｜瑞芬太尼｜methyl 1-(3-methoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate｜C20H28N2O5｜132875-61-7

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｜Remifentanil bis ethyl ester｜ethyl 1-(3-ethoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate

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｜RR49 ｜N1-2-Fluoro-2-(2-fluorophenyl)ethylpiperidin-4-ylN-phenylpropanamide｜2376328-79-7

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｜SR-16412 ｜1-(1-benzylpiperidin-4-yl)-3H-indol-2-one｜16223-24-8

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｜开环芬太尼｜N-phenyl-N-{4-methyl(2-phenylethyl)aminobutan-2-yl}propanamide｜C22H30N2O｜253342-66-4

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｜舒芬太尼｜N-4-(Methoxymethyl)-1-(2-thiofuran-2-ylethyl)-4-piperidyl-N-phenylpropanamide｜C22H30N2O2S｜56030-54-7

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｜Thiafentanil｜methyl 4-(N-(2-methoxyacetyl)anilino)-1-(2-thiophen-2-ylethyl)piperidine-4-carboxylate｜101345-60-2

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｜Trefentanyl｜N1-2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl-4-phenylpiperidin-4-ylN-(2-fluorophenyl)propanamide｜120656-93-1

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｜Trifluorofentanyl ｜N-(3,4-difluorophenyl)-N-1-(2-4-fluorophenylethyl)-4-piperidinyl-propanamide

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｜Tropafentanyl (Fentanyl tropane)｜N-phenyl-N-8-(2-phenylethyl)-8-azabicyclo3.2.1octan-3-ylpropanamide

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｜`3,4-dichloro-4''-methoxyfentanyl`｜N-(3,4-dichlorophenyl)-N-1-(2-4-methoxyphenylethyl)-4-piperidinyl-propanamide｜1161705-29-8