Simplify the following text for a Grade 6 native English-speaking person.
Original: `` Historic Route 66 '' runs for a significant distance in and near Flagstaff , Arizona . Farther west , a long segment of Route 66 in Arizona runs significantly north of Interstate 40 , and it is designated as State Route 66 .
Simplified: One of the original U.S. highways , Route 66 , US Highway 66 , was established on November 11 , 1926 .