[EVO 4G Q&A, Help & Troubleshooting] omegasun18:
yes you can remove HTC sense. it is a little more involved them just removing one file but not a lot.

you will want to remove the following .apks at the very least but can remove additional ones that wont be doing anything (ie htc sense widgets and apps)

HtcLocationService.apk

HtcLocationPicker.apk

Rosie.apk

HtcAddProgramWidget.apk (also known as rosie utility if removing via titanium back up)

I have a script i use to remove most of the bloatware I just added the sense apks if you want to give it a try.

I have attached it it is not signed but is flash able with clockwork it removes the majority of the htc widgets, sprint bloat ware and sense. It also removes the peer networking programs (i dont use the default ones so no biggie for me)

below is the code you could always edit it and replace the script in the zip if you want additional or less taken out

show_progress 0.1 0
delete SYSTEM:app/com.htc.StockWidget.apk
delete SYSTEM:app/Stock.apk
delete SYSTEM:app/Sprint_TV.apk
delete SYSTEM:app/Sprint_NFL.apk
delete SYSTEM:app/Sprint_NASCAR.apk
delete SYSTEM:app/HtcFootprintsWidget.apk
delete SYSTEM:app/HtcFootprints.apk
delete SYSTEM:app/HtcCarPanel.apk
delete SYSTEM:app/HtcClockWidget.apk
delete SYSTEM:app/HtcFacebook.apk
delete SYSTEM:app/com.htc.HtcFriendStream.apk
delete SYSTEM:app/com.htc.HtcFriendStreamWidget.apk
delete SYSTEM:app/LatinIME.apk
delete SYSTEM:app/GSD.apk
delete SYSTEM:app/FieldTest.apk
delete SYSTEM:app/amazonmp3.apk
delete SYSTEM:app/se.laetus.lwp.beziers.apk
delete SYSTEM:app/htcmsgwidgets.apk
delete SYSTEM:app/htcbookmarkwidget.apk
delete SYSTEM:app/htcmailwidgets.apk
delete SYSTEM:app/com.geekyouup.android.wallpaper.apk
delete SYSTEM:app/com.discoverdroid.mystify.apk
delete SYSTEM:app/Sprint_TVWidget.apk
delete SYSTEM:app/SDSA.apk
delete SYSTEM:app/HtcPhotoWidget.apk
delete SYSTEM:app/Morelocale.apk
delete SYSTEM:app/DCSStock.apk
delete SYSTEM:app/IM.apk
delete SYSTEM:app/VoiceDialer.apk
delete SYSTEM:app/HtcTwitter.apk
delete SYSTEM:app/HtcPhotoWidget.apk
delete SYSTEM:app/HTCMobileGuide.apk
delete SYSTEM:app/FieldTest.apk
delete SYSTEM:app/com.htc.TwitterWidget.apk
delete SYSTEM:app/NewsReader.apk
delete SYSTEM:app/com.htc.NewsReaderWidget.apk
delete SYSTEM:app/Flickr.apk
delete SYSTEM:app/HtcRingtoneTrimmer.apk
delete SYSTEM:app/BugReporter.apk
delete SYSTEM:app/logcollector.apk
delete SYSTEM:app/HtcFMRadio.apk
delete SYSTEM:app/htcsettingwidgets.apk
delete SYSTEM:app/WifiRouter.apk
delete SYSTEM:app/FieldTrial.apk
delete SYSTEM:app/RSS.apk
delete SYSTEM:app/HtcLocationService.apk
delete SYSTEM:app/HtcLocationPicker.apk
delete SYSTEM:app/Rosie.apk
delete SYSTEM:app/Mode10Wallpapers.apk
delete SYSTEM:app/HtcAddProgramWidget.apk
show_progress 0.1 10

show_progress 0.2 0
delete DATA:data/com.htc.FriendStreamWidget
delete DATA:data/com.htc.NewsReaderWidget
delete DATA:data/com.htc.TwitterWidget
delete DATA:data/com.htc.htcbookmarkwidget
delete DATA:data/com.htc.htcmailwidgets
delete DATA:data/com.htc.htcmsgwidgets
delete DATA:data/com.htc.htctwitter
delete DATA:data/com.htc.android.teeter
delete DATA:data/com.xtralogic.android.logcollector.usage
delete DATA:data/com.SIE.HTCMobileGuide
delete DATA:data/com.mobitv.client.sprinttv
delete DATA:data/com.htc.android.htcsetupwizard
delete DATA:data/com.htc.friendstream
delete DATA:data/com.htc.katana
delete DATA:data/com.sprint.ce.updater
delete DATA:data/com.htc.fm
delete DATA:data/com.mobitv.client.sprinttv
delete DATA:data/com.htc.newsreader
delete DATA:data/org.adw.launcher
show_progress 0.2 10