[Google Pixel Questions & Answers] mnguyen127:
I have both the HTC 10 and the Pixel.

Aesthetically, I prefer the HTC 10. I've had more people ask me about what phone I was using when I was using the 10 as my daily driver than any other phone I've ever owned. The chamfered edges have a way of catching light that just draws people's eyes to it. That's not to say that I don't like the Pixel, but the HTC 10 just seems like it's in a world of its own in terms of build design. The only person who commented on my Pixel said to me, "That's the weirdest looking phone I've ever seen. It looks like a weird iPhone."

I also preferred the sound coming out of the headphone jack and dual (top and bottom) firing speakers on the HTC 10 over the Pixel's setup. Blocking the sound coming out of the Pixel's single bottom firing speaker is just insanely easy, and I find myself contorting my hands awkwardly in order not to block it when I'm watching media or playing games.

I also liked the HTC 10's fingerprint scanner location and the off screen buttons better than the Pixel's setup. That's just a personal preference though.

If you're worried about receiving timely updates on either phone, it's a non-issue. The amount of OTA updates on the HTC 10 has also been seriously fantastic. I've never had any phone that has consistently gotten as many updates as the HTC 10. It honestly makes most brands look like a joke, and I'm still waiting for my first update for my 10 while my HTC 10 just received Nougat.

With that said, there are a few things that are far superior on the Pixel.

I prefer the AMOLED screen on the Pixel for outdoor viewing. The higher contrast ratio seems to make viewing and reading a lot easier, and it also feels a bit brighter than HTC's LCD screen, which could be extremely difficult to read in direct bright California sunlight. The Pixel is not the brightest screen I've ever used, but it's certainly a lot brighter than the HTC 10. This always bothered me about the HTC 10 since I spend a few hours a day walking to work or in direct sunlight.

The camera on the Pixel is just amazingly consistent for the most part. The HTC 10 has this weird lense flare issue where if the camera lens is even slightly smudged, it creates the most insane lens flares I've seen, and whatever material is used on lens of the HTC 10 is just absurdly prone to fingerprint smudges. It's also really difficult to wipe it off entirely. I'm not sure if this issue has been remedied with the Nougat update, but there are some posts floating around on the HTC 10 forum indicating that the lens flare has been significantly improved. The Pixel, even without taking into consideration of the HTC 10's lens flare issue, just seems to be an overall better camera.

It's also significantly faster at snapping shots than the HTC 10.

I also generally find my wireless connection better on the Pixel. Battery life on the Pixel also seems slightly better to me.

I bought the 128GB Pixel so storage has been a non issue with me, but thinking back at it, the only time storage might've become an issue on my 32GB HTC 10 would've been when I went to Europe and loaded my phone with media for that 11 hour flight. Otherwise, 32GB with non-expandable storage would still probably be fine for me. I only bought the 128GB since 64GB wasn't available for the Pixel.