[Galaxy Note 10.1 (2014 Edition) Q&A, Help & Troubl] {Diemex}:
Screen Protectors

I don't use them, but have a fellow student that uses one and it seems to work well. Bare in mind it adds some friction if you get a mate screenprotector.

S-Note

Nope never used never tried and just got LectureNotes from the start. I also write in portrait mode. Most fellow students like to write in landscape. I have found that I can write extremely small and read it and don't like to scroll down all the time.

Speed and Precision

Yes it's fast enough. I write in my maths lecture. For me it's faster than paper. I use the plastic tip and there is hardly any friction so the pen moves very fast. Only thing that takes time is when you have to fiddle with menus or stuff like that.

Samsungs Software (and how i can get rid of their butt-ugly touchwiz crap?)

Lags and Stuff

I have had no problems with my device. Even at the beginning I didn't really notice much lag. But there are lots of people that have complained. Once you disable a bunch of touchwiz apps it flies.

Touchwizz

If you disable some touchwiz stuff it will perform a bit faster. I disabled everything but S-Note, Alarms, Action Note and the S-Pen SDK.

Other Apps

Due to the high pixel density some apps that aren't optimized (are badly coded) and perform lots of drawing might not perform as well. But other than that no real issues.

Custom Rom Stuff

General Support

The rom support has been bad. But this is the first device I bought in the launch week so it might pick up.

Rooting and Knox

If you root the know counter will be tripped and you allegedly lose warranty. It seems to be some corporate app allowing you to separate work and company data.

This is my Wishlist for a Custom Rom. Will that ever happen?

S-Pen Support for Notetaking (with anything other than S-Note)

There are native API for styluses as long as the drivers work the native API's should work too

Multiwindow Support (i suppose that is bound to touchwizz but have there been ROMs that integrated it into Stock-ish Android before?)

The multiwindow support on touchwiz is the best I have seen so far.

Hardware

Battery life

My battery lasts about 7 hours with screen on. If you need more battery life get an external battery. They are really cheap, in germany i can get one for 40 bucks with double the capacity as the internal battery.

Bigger Stylus

There seems to be one wacom stylus that works, there is a thread about it. I like the small pen, it's light and I don't get tired when writing with it.

Smart Wake

yes supports the smart wake

Cover

I have an ivso cover i got from amazon.de I'm happy with it

I got the Note about a month ago or so for university. I didn't really plan on replacing paper with that, but no I don't use paper at all anymore. I have found that I can keep stuff organized a lot better in a digital form. If I ever get a sheet of paper I will either run to the scanners scattered around our university and scan it or take a picture and annotate that instead of the actual paper :D. It really depends on the way of learning if you can "think digitally". A fellow student got the old model and returned it after a week because he found it too distracting. But for me the Note really fits into my way of thinking and doing stuff, but I'm a real techy person, who programs and sees a higher value in having information in a digital form.