[Verizon HTC Droid Incredible 4G LTE] IceDragon59:
There are some interesting tips and tricks for this phone, and some observations I've made. This is definitely not a complete list, I just wanted to put some things that keep popping up in various threads into one central place.

TIPS:

Buy a screen protector and case! You will significantly increase the longevity of your phone.

When you're not using it, turn off Wi-Fi, 4G, and GPS. It will improve your battery life significantly.

If using the stock messaging app, you can improve load time and performance by limiting the number of messages saved in Messages -> Settings -> General -> Delete old messages.

Under Settings -> Developer options, there are several options which can improve performance on your phone, such as reducing transition time, enabling GPU rendering, and destroying background activities.

For those of you who came from Sense 1.0, you can now backup and restore your dictionary and messages to the SD card.

Messages: Messages -> 3 Dot -> Back up SMS

Dictionary: Settings -> Language and keyboard -> HTC Sense Input -> Personal dictionary -> Sync personal dictionary

TRICKS:

Disable bloatware while on stock: To disable any apps which you are forced to have on your phone but you don't use, go to Settings -> Apps, and go to each app you don't want, uninstall updates if it has any, then click Disable.

Safe mode: Restart your phone, hold volume down starting from when the screen first goes dark until the OS is loaded. If done successfully, you will see the words 'Safe mode' in the bottom of your screen.

EPST: Dial ##778 on your phone and edit developer options and programming codes. You can seriously screw up your phone if you don't know what you're doing, so proceed with caution.

Change number of home screens: Touch your home button twice. A display of all your home screens at the same time will appear.

To remove screens, long-press any screens you no longer want (you have to leave your primary screen with the small picture of the house on it), and drag it to the top to 'Remove'.

To add more panels when you have less than 7, which is the maximum, touch 'Add Panel' at the top. You can rearrange these to any order you wish.

HBOOT: To access HBOOT, turn off Fast boot in Settings -> Power, hold your power button, hit 'Restart', and when the capacitive buttons at the bottom turn off, hold the Volume Down button until it loads HBOOT.

Quickly change all sounds: You can quickly change all ringtones, notifications, and alarms by going to Settings -> Personalize -> Sound tab at the bottom.

Global phone: To enable Global phone mode, go to Settings -> Call, and change Preferred Network to Global.

OBSERVATIONS

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As with every phone model, every individual unit is not created equal. You will encounter a problem with your phone, most likely one easily rectified once we get root. You might have slow Wi-Fi, an imperfectly-fitting case, or any number of things. If it's a hardware issue, you will likely discover it before your 14 day exchange period is up. Don't be afraid to exchange it! If it's software-related, wait for root and we'll see what can be done.

Some things that were handled by the OS in previous iterations has to be done manually now, such as automatically deleting blank pictures from the Gallery app that were deleted with a file explorer or on the computer. It can be a nuisance, but without root, we can't change anything right now.

Suggestions to this list are welcome. Some things some of us take for granted are great additions to this list for the uninitiated.