Table:
0
A
B
C
D
E
F
G
1
Enzyme
Location
Substrate
Product
Chromosome
OMIM
Porphyria
2
ALA synthase
Mitochondrion
Glycine , succinyl CoA
δ-Aminolevulinic acid
3p21.1
125290
none
3
ALA dehydratase
Cytosol
δ-Aminolevulinic acid
Porphobilinogen
9q34
125270
ALA-Dehydratase deficiency
4
PBG deaminase
Cytosol
Porphobilinogen
Hydroxymethyl bilane
11q23.3
176000
acute intermittent porphyria
5
Uroporphyrinogen III synthase
Cytosol
Hydroxymethyl bilane
Uroporphyrinogen III
10q25.2-q26.3
606938
congenital erythropoietic porphyria
6
Uroporphyrinogen III decarboxylase
Cytosol
Uroporphyrinogen III
Coproporphyrinogen III
1p34
176100
porphyria cutanea tarda
7
Coproporphyrinogen III oxidase
Mitochondrion
Coproporphyrinogen III
Protoporphyrinogen IX
3q12
121300
coproporphyria
8
Protoporphyrinogen oxidase
Mitochondrion
Protoporphyrinogen IX
Protoporphyrin IX
1q22
600923
variegate porphyria
9
Ferrochelatase
Mitochondrion
Protoporphyrin IX
Heme
18q21.3
177000
erythropoietic protoporphyria

Questions and formulas:
Question: What is the location of the enzyme Uroporphyrinogen iii Synthase?
Formula: FILTER(B1,A1="uroporphyrinogen iii synthase")
Formula2: FILTER(B2:B9,A2:A9="uroporphyrinogen iii synthase")
Level: easy
Question: What is protoporphyrin ix's substrate?
Formula: FILTER(C1,D1="protoporphyrin ix")
Formula2: FILTER(C2:C9,D2:D9="protoporphyrin ix")
Level: easy
Question: Which substrate has an OMIM of 176000?
Formula: FILTER(C1,F1=176000)
Formula2: FILTER(C2:C9,F2:F9=176000)
Level: easy