Question: When was the Great Plague in the city where the director of What a Crazy World died?

<P0-S0> the first european epidemic of the bubonic plague dates back to the mid 6th century and is called the plague of justinian. <P0-S1> the largest plague epidemic was the black death in europe in the 14th century. <P0-S2> in medieval times, the large loss of people (due to the bubonic plague) in a town created an economic disaster. <P0-S3> community plague doctors were quite valuable and were given special privileges; for example, plague doctors were freely allowed to perform autopsies, which were otherwise generally forbidden in medieval europe, to research a cure for the plague.in some cases, plague doctors were so valuable that when barcelona dispatched two to tortosa in 1650, outlaws captured them en route and demanded a ransom. <P0-S4> the city of barcelona paid for their release. <P0-S5> the city of orvieto hired matteo fu angelo in 1348 for four times the normal rate of a doctor of 50-florin per year. <P0-S6> pope clement vi hired several extra plague doctors during the black death plague. <P0-S7> they were to attend to the sick people of avignon. <P0-S8> of 18 doctors in venice, only one was left by 1348: five had died of the plague, and 12 were missing and may have fled. <SEP> <P1-S0> What a Crazy World is a 1963 film directed by Michael Carreras from a script by Carreras and Alan Klein, from the latter's stage play. <P1-S1> It is a pop musical featuring a number of late 1950s and early 1960s pop acts, including an appearance by Freddie and the Dreamers. <SEP> <P2-S0> Michael Carreras (21 December 1927, in London – 19 April 1994, in London) was a British film producer and director. <P2-S1> He was known for his association with Hammer Studios, being the son of founder James Carreras, and taking an executive role in the company during its most successful years. <SEP> <P3-S0> the black death is thought to have originated in the arid plains of central asia, where it then travelled along the silk road, reaching crimea by 1343. from there, it was most likely carried by oriental rat fleas living on the black rats that were regular passengers on merchant ships. <P3-S1> spreading throughout the mediterranean and europe, the black death is estimated to have killed 30–60% of europe's total population. <P3-S2> in total, the plague reduced the world population from an estimated 450 million down to 350–375 million in the 14th century. <P3-S3> the world population as a whole did not recover to pre-plague levels until the 17th century. <P3-S4> the plague recurred occasionally in europe until the 19th century. <SEP> <P4-S0> In England, in the absence of census figures, historians propose a range of preincident population figures from as high as 7 million to as low as 4 million in 1300, and a postincident population figure as low as 2 million. <P4-S1> By the end of 1350, the Black Death subsided, but it never really died out in England. <P4-S2> Over the next few hundred years, further outbreaks occurred in 1361–62, 1369, 1379–83, 1389–93, and throughout the first half of the 15th century. <P4-S3> An outbreak in 1471 took as much as 10–15% of the population, while the death rate of the plague of 1479–80 could have been as high as 20%. <P4-S4> The most general outbreaks in Tudor and Stuart England seem to have begun in 1498, 1535, 1543, 1563, 1589, 1603, 1625, and 1636, and ended with the Great Plague of London in 1665.