Question: When was the Great Plague in the city where the person who gave her blessing to further privateering raids against Spanish ports born?

In England, in the absence of census figures, historians propose a range of preincident population figures from as high as 7 million to as low as 4 million in 1300, and a postincident population figure as low as 2 million. By the end of 1350, the Black Death subsided, but it never really died out in England. Over the next few hundred years, further outbreaks occurred in 1361–62, 1369, 1379–83, 1389–93, and throughout the first half of the 15th century. The most general outbreaks in Tudor and Stuart England seem to have begun in 1498, 1535, 1543, 1563, 1589, 1603, 1625, and 1636, and ended with the Great Plague of London in 1665. An outbreak in 1471 took as much as 10–15% of the population, while the death rate of the plague of 1479–80 could have been as high as 20%. <SEP> In the meantime the Protestant Reformation had turned England and Catholic Spain into implacable enemies . No further attempts to establish English colonies in the Americas were made until well into the reign of Queen Elizabeth I, during the last decades of the 16th century. In 1562, the English Crown encouraged the privateers John Hawkins and Francis Drake to engage in slave-raiding attacks against Spanish and Portuguese ships off the coast of West Africa with the aim of breaking into the Atlantic trade system. This effort was rebuffed and later, as the Anglo-Spanish Wars intensified, Elizabeth I gave her blessing to further privateering raids against Spanish ports in the Americas and shipping that was returning across the Atlantic, laden with treasure from the New World. At the same time, influential writers such as Richard Hakluyt and John Dee (who was the first to use the term "British Empire") were beginning to press for the establishment of England's own empire. By this time, Spain had become the dominant power in the Americas and was exploring the Pacific ocean, Portugal had established trading posts and forts from the coasts of Africa and Brazil to China, and France had begun to settle the Saint Lawrence River area, later to become New France. <SEP> She was educated privately at home. Elizabeth was born in London to the Duke and Duchess of York, later King George VI and Queen Elizabeth, and was the elder of their two daughters. Her father acceded to the throne on the abdication of his brother Edward VIII in 1936, from which time she was the heir presumptive. She began to undertake public duties during World War II, serving in the Auxiliary Territorial Service. In 1947, she married Philip, Duke of Edinburgh, with whom she has four children: Charles, Anne, Andrew, and Edward. <SEP> the present city of heraklion was founded in 824 by the arabs under abu hafs umar who had been expelled from al-andalus by emir al-hakam i and had taken over the island from the eastern roman empire. they built a moat around the city for protection, and named the city ربض الخندق, "rabḍ al-ḫandaq" ("castle of the moat"). it became the capital of the emirate of crete (ca. 827–961). the saracens allowed the port to be used as a safe haven for pirates who operated against imperial (byzantine) shipping and raided imperial territory around the aegean. <SEP> the spanish armada (spanish: grande y felicísima armada, literally ``great and most fortunate navy '') was a spanish fleet of 130 ships that sailed from a coruña in late may 1588, under the command of the duke of medina sidonia, with the purpose of escorting an army from flanders to invade england. the strategic aim was to overthrow queen elizabeth i and her establishment of protestantism in england, with the expectation that this would put a stop to english interference in the spanish netherlands and to the harm caused to spanish interests by english and dutch privateering.