Question: China Bio-Immnunity has developed a vaccine for which viral disease that causes brain inflammation?

 Early symptoms can include fever and tingling at the site of exposure. Rabies is a viral disease that causes inflammation of the brain in humans and other mammals.  These symptoms are followed by one or more of the following symptoms: violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness.  Once symptoms appear, the result is nearly always death.  The time period between contracting the disease and the start of symptoms is usually one to three months; however, this time period can vary from less than one week to more than one year.  The time is dependent on the distance the virus must travel to reach the central nervous system. <SEP> West Nile fever is a mosquito-borne infection by the West Nile virus.  Approximately 80% of West Nile virus infections in humans have few or no symptoms.  In the cases where symptoms do occur—termed West Nile fever in cases without neurological disease—the time from infection to the appearance of symptoms is typically between 2 and 15 days.  Symptoms may include fever, headaches, feeling tired, muscle pain or aches, nausea, loss of appetite, vomiting, and rash.  Less than 1% of the cases are severe and result in neurological disease when the central nervous system is affected.  People of advanced age, the very young, or those with immunosuppression, either medically induced, such as those taking immunosuppressive drugs, or due to a pre-existing medical condition such as HIV infection, are most susceptible.  The specific neurological diseases that may occur are West Nile encephalitis, which causes inflammation of the brain, West Nile meningitis, which causes inflammation of the meninges, which are the protective membranes that cover the brain and spinal cord, West Nile meningoencephalitis, which causes inflammation of the brain and also the meninges surrounding it, and West Nile poliomyelitis—spinal cord inflammation, which results in a syndrome similar to polio, which may cause acute flaccid paralysis. <SEP> BCG disease is an adverse effect of the Bacillus Calmette-Guérin vaccine.  The vaccine contains living "Mycobacterium bovis" BCG, and in BCG disease, the bacterium causes a disease in persons vaccinated.  Between 2000 and 2006, several hundred children in Finland had serious adverse events from the vaccine, including osteitis and osteomyelitis, disseminated (usually fatal) BCG infection, arthritis, and lymph node abscesses.  Four deaths were registered in the official adverse event register, and while in only two cases a clear causal link was considered to be in place, two other cases were diagnosed with a disease which in scientific peer-reviewed articles (case descriptions) have been mistakenly first made, and afterward have been noticed to be disseminated BCG infections.  One death with a causal link considered established by the adverse event monitoring agency was vaccinated with pre-August 2002 vaccine (Evans), while the three other registered deaths were with the new post-August 2002 vaccine (BCG Vaccine SSI). <SEP>  The Company has sales and marketing efforts in the 24 main provinces and major cities in the People's Republic of China (PRC).  Its principal products, its Rabies Vaccine and Mumps Vaccine, are sold and distributed by a network of wholesale distributors, as well as through retail customers. China Bio-Immunity, based in Dalian, China, is largest developer, producer, manufacturer of vaccine-based prophylactics and therapeutics.  In addition to the current distribution structure, the Company plans to further market its products through distribution agreements with local agents in several developing countries, including, but not limited to South Asia, South Africa, and countries throughout Southeast Asia.