Question:  Darwin's Black Box: The Biochemical Challenge to Evolution is a book by an American biochemist best known for his argument for his stance on what?

<P0-S0> The Edge of Evolution: The Search for the Limits of Darwinism is an intelligent design book by Discovery Institute fellow Michael Behe, published by the Free Press in 2007. <P0-S1>  Behe argues that while evolution can produce changes within species, there is a limit to the ability of evolution to generate diversity, and this limit (the "edge of evolution") is somewhere between species and orders. <P0-S2>  On this basis, he says that known evolutionary mechanisms cannot be responsible for all the observed diversification from the last universal ancestor and the intervention of an intelligent designer can adequately account for much of the diversity of life. <P0-S3>  It is Behe's second intelligent design book, his first being "Darwin's Black Box". <SEP> <P1-S0> Michael J. Behe ( ; born January 18, 1952) is an American biochemist, author, and intelligent design (ID) advocate. <P1-S1>  He serves as professor of biochemistry at Lehigh University in Pennsylvania and as a senior fellow of the Discovery Institute's Center for Science and Culture. <P1-S2>  Behe is best known for his argument for his stance on irreducible complexity (IC), which argues that some biochemical structures are too complex to be explained by known evolutionary mechanisms and are therefore probably the result of intelligent design. <P1-S3>  Behe has testified in several court cases related to intelligent design, including the court case "Kitzmiller v. Dover Area School District" that resulted in a ruling that intelligent design was not science and was religious in nature. <SEP> <P2-S0> Xiaodong Wang (, born 1963) is a Chinese-born American biochemist best known for his work with cytochrome c. <P2-S1>  His laboratory developed an in-vitro assay for the activation of the apoptosis related proteinase Caspase-3. <P2-S2>  This allowed the biochemical purification of a complex of Cytochrome c, Caspase-9 and the Apoptotic Protease Activating factor-1 (APAF1). <P2-S3>  These components are essential for forming a ternary complex called the apoptosome that activates Caspase-3 downstream of the intracellular or mitochondrial pathway of apoptosis. <SEP> <P3-S0> Darwin's Black Box: The Biochemical Challenge to Evolution (1996; second edition 2006) is a book by Michael J. Behe, a professor of biochemistry at Lehigh University in Pennsylvania and a senior fellow of the Discovery Institute's Center for Science and Culture. <P3-S1>  In the book Behe presents his notion of irreducible complexity and argues that its presence in many biochemical systems therefore indicates that they must be the result of intelligent design rather than evolutionary processes. <P3-S2>  In 1993, Behe had written a chapter on blood clotting in "Of Pandas and People", presenting essentially the same arguments but without the name "irreducible complexity", which he later presented in very similar terms in a chapter in "Darwin's Black Box". <P3-S3>  Behe later agreed that he had written both and agreed to the similarities when he defended intelligent design at the "Kitzmiller v. Dover Area School District" trial.