Question: When did the Greek Orthodox Church split from the city where the developer of Annunciation of Cortona died?

<P0-S0> In 476, when the last emperor of the western part of the Roman Empire was deposed and the western imperial insignia were sent to Constantinople, there was once again a single Roman Emperor. <P0-S1> However, he had little power in the West, which was ruled almost entirely by various Germanic tribes. <P0-S2> In the opinion of Randall R. Cloud, the permanent separation of the Greek East from the Latin West was ``the fundamental reason for the estrangement that soon followed between the Greek and the Latin Christians ''. <SEP> <P1-S0> vladimir's choice of eastern christianity may also have reflected his close personal ties with constantinople, which dominated the black sea and hence trade on kiev's most vital commercial route, the dnieper river. <P1-S1> adherence to the eastern church had long-range political, cultural, and religious consequences. <P1-S2> the church had a liturgy written in cyrillic and a corpus of translations from greek that had been produced for the slavic peoples. <P1-S3> this literature facilitated the conversion to christianity of the eastern slavs and introduced them to rudimentary greek philosophy, science, and historiography without the necessity of learning greek (there were some merchants who did business with greeks and likely had an understanding of contemporary business greek). <P1-S4> in contrast, educated people in medieval western and central europe learned latin. <P1-S5> enjoying independence from the roman authority and free from tenets of latin learning, the east slavs developed their own literature and fine arts, quite distinct from those of other eastern orthodox countries. <P1-S6> [citation needed] (see old east slavic language and architecture of kievan rus for details ). <P1-S7> following the great schism of 1054, the rus' church maintained communion with both rome and constantinople for some time, but along with most of the eastern churches it eventually split to follow the eastern orthodox. <P1-S8> that being said, unlike other parts of the greek world, kievan rus' did not have a strong hostility to the western world. <SEP> <P2-S0> Vasari claims that at this time Fra Angelico was offered the Archbishopric of Florence by Pope Nicholas V, and that he refused it, recommending another friar for the position. <P2-S1> The story seems possible and even likely. <P2-S2> However, if Vasari's date is correct, then the pope must have been Eugene IV and not Nicholas, who was elected Pope only on 6 March 1447. <P2-S3> Moreover, the archbishop in 1446–1459 was the Dominican Antoninus of Florence (Antonio Pierozzi), canonized by Pope Adrian VI in 1523. <P2-S4> In 1447 Fra Angelico was in Orvieto with his pupil, Benozzo Gozzoli, executing works for the Cathedral. <P2-S5> In 1445 Pope Eugene IV summoned him to Rome to paint the frescoes of the Chapel of the Holy Sacrament at St Peter's, later demolished by Pope Paul III. <P2-S6> Among his other pupils were Zanobi Strozzi. <SEP> <P3-S0> treia cathedral, otherwise the church of the annunciation (, ) is a roman catholic cathedral in the city of treia, macerata, italy, dedicated to the annunciation. <P3-S1> it was formerly the seat of the bishop of treia from the creation of the diocese of treia in 1817 to its merging into the diocese of san severino in 1920, and following several other mergers is now a co-cathedral of the diocese of macerata-tolentino-recanati-cingoli-treia. <SEP> <P4-S0> The Annunciation of Cortona is a panel-painting altarpiece or retable by Fra Angelico: once housed in the Church of Gesù of Cortona, it is now held at the Museo Diocesano in Cortona.